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Dissertations / Theses on the topic 'Glycyrrhizae'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Sappe, Françoise. "Etude de génines stéréoi͏̈diques et de flavonoi͏̈des issu de Glycyrrhiza S." Aix-Marseille 3, 1995. http://www.theses.fr/1996AIX30026.

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Les racines et les rhizomes de glycyrrhiza sp. Contiennent des saponosides triterpeniques parmi lesquels l'acide glycyrrhizique est le principal representant. L'hydrolyse de cet acide conduit a de l'acide 18 beta-glycyrrhetinique (acide 18 beta) qui possede des proprietes anti-inflammatoire et anti-ulcereuse. Cependant, lors de l'hydrolyse, l'acide 18 beta peut s'isomeriser partiellement en acide 18 alpha-glycyrrhetinique (acide 18 alpha). L'utilisation de l'acide 18 beta en therapie humaine necessite de disposer d'une methode de dosage de l'acide 18 alpha dans l'acide 18 beta. Deux methodes d

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2

Feltrin, Andrieli Cassel. "ESTUDO COMPARATIVO DE Glycyrrhiza glabra (ALCAÇUZ) E Periandra dulcis (ALCAÇUZ-DA-TERRA)." Universidade Federal de Santa Maria, 2010. http://repositorio.ufsm.br/handle/1/5939.

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The Fabaceae family is comprised of approximately 18 000 species in 650 genera, with wide geographic distribution. The species Glycyrrhiza glabra (licorice) and Periandra dulcis (licorice-of-the-earth) belong to the family Fabaceae. Licorice displays a variety of pharmacological activities, such as antiulcer, antiinflammatory, antioxidant, antimicrobial, among others. In ethnomedicine Brazilian, P. dulcis is used as a substitute/adulterant G. glabra. This study aimed to differentiate plants for antioxidant activity, the HPLC chromatographic profile and the antimicrobial activity. Plants roots

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3

Carvalho, Paulo Henrique Dias de. "Isolamento e identificação da licochalcona A a partir da Glycyrrhiza inflata e avaliação de suas atividades citotóxica in vitro e hepatoprotetora em modelo de lesão hepática em ratos." Universidade Federal de Juiz de Fora, 2013. https://repositorio.ufjf.br/jspui/handle/ufjf/1840.

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Submitted by Renata Lopes (renatasil82@gmail.com) on 2016-06-16T19:51:10Z No. of bitstreams: 1 paulohenriquediasdecarvalho.pdf: 3125617 bytes, checksum: 3e951b5c5e73d3862e1ed9b6e9e28451 (MD5)<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2016-07-13T14:26:36Z (GMT) No. of bitstreams: 1 paulohenriquediasdecarvalho.pdf: 3125617 bytes, checksum: 3e951b5c5e73d3862e1ed9b6e9e28451 (MD5)<br>Made available in DSpace on 2016-07-13T14:26:36Z (GMT). No. of bitstreams: 1 paulohenriquediasdecarvalho.pdf: 3125617 bytes, checksum: 3e951b5c5e73d3862e1ed9b6e9e28451

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4

Gumiero, Viviane Cristina. "Desenvolvimento e avaliação de nanoemulsões à base de óleo de babaçu (Orbignya oleifera) e extratos vegetais (Areca catechu, Glycyrrhiza glabra e Portulaca oleracea) para uso pós-sol." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/60/60137/tde-30112011-084007/.

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A nanotecnologia é aplicada em praticamente todos os setores da ciência, incluindo a área cosmética. Nanoemulsões apresentam-se mais estáveis do que macroemulsões, possuem boa espalhabilidade e facilitam a penetração de ativos na pele. O óleo de babaçu (Orbignya oleifera) é utilizado no tratamento de várias afecções da pele, devido às propriedades anti-inflamatória, cicatrizante e antiséptica. O extrato de sementes de Areca catechu inibe a produção de elastase e colagenase, enzimas responsáveis pela flacidez e perda de elasticidade da pele no envelhecimento. Além disso, possui ação antioxidant

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5

Ho, Wing-tak, and 何永德. "Glycyrrhizic acid potentiates dsRNA-induced nitric oxide generation inalveolar macrophages." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31971799.

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6

Ho, Wing-tak. "Glycyrrhizic acid potentiates dsRNA-induced nitric oxide generation in alveolar macrophages." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B31971799.

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7

Schmid, Christian [Verfasser]. "Geschmacksaktive Saponine in Süßholz (Glycyrrhiza glabra L.): Strukturaufklärung, Psychophysik und Aktivierung von Süß- und Bittergeschmacksrezeptoren / Christian Schmid." München : Verlag Dr. Hut, 2019. http://d-nb.info/1198542969/34.

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8

Wang, Di, and 王迪. "Molecular and biochemical characterization of therapeutic properties of paeoniae-glycyrrhiza decoction, a Chinese herbal preparation, against antipsychotic-associated hyperprolactinemia." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193412.

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Hyperprolactinemia (hyperPRL) is a highly prevalent adverse side effect in antipsychotic therapy as most antipsychotic drugs are dopamine D2 receptor antagonists. Peony-Glycyrrhiza Decoction (PGD, 芍藥甘草湯) is a classic Chinese herbal formula initially used to treat muscle pain and spasm. Our pilot clinical studies have confirmed the effectiveness of PGD in alleviating antipsychotic-induced hyperPRL in patients with schizophrenia. In the present study, we further examined the effects of PGD, its individual herbal preparations and major compounds in suppressing prolactin (PRL) hyperactivity in in

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9

Barghi, Nasrine. "Les différents niveaux de la variabilité caryotypique et morphologique (développement hétéroblastique) dans les genres Glycyrrhiza L. Et Astragalus L." Paris 11, 1985. http://www.theses.fr/1985PA112356.

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Ce travail relatif à trois espèces de Glycyrrhiza (G. Echinata, G. Glabra – la Vraie Réglisse, G. Lepidota) et l’Astragalus glycyphyllos (Fausse Réglisse) a permis à différents niveaux (espèce, population, individu, organe) de mettre en évidence et d(étudier des variations d’ordre caryotypique (par exemple existence possible de mosaïques chromosomiques chez certains individus d’A. Glycyphyllos) ou morphologique (vitesse et intensité du développement hétéroblastique, phénomène de rajeunissement accompagnant la ramification). L’intégration de tous les résultats obtenus autorise à ranger de l’esp

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10

Campisi, Mirko Antonello Rosario. "Chimica, valutazione delle proprietà antiossidanti e delle attività anti-genotossica ed antiinfiammatoria dei fitocomplessi dalla liquirizia (Glycyrrhiza glabra L.)." Doctoral thesis, Università di Catania, 2013. http://hdl.handle.net/10761/1395.

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Da millenni la liquirizia è utilizzata dall uomo come rimedio terapeutico, in particolare in diverse medicine tradizionali. In questo studio da noi effettuato abbiamo che GA (l acido 18-beta glicirretinico) è un potente inibitore della epatotossicità da accumulo di acidi biliari negli epatociti di ratto; è stata inoltre dimostrata la capacità della glicirrizina di inibire la produzione di radicali liberi, che sono una classe di potenti agenti flogogeni, da parte dei granulociti neutrofili. Dai dati esaminati quindi, possiamo concludere affermando che la liquirizia (Glycyrrhiza glabra L.). ed

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11

Astafyeva, Oxana <1987&gt. "L'uso di Glycyrrhiza glabra L., Achillea micrantha Wild. ed Helicrysum arenarium L. per la preparazione di prodotti con proprietà antibatteriche." Doctoral thesis, Università Ca' Foscari Venezia, 2013. http://hdl.handle.net/10579/3073.

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Lo scopo della tesi è stato quello di studiare la possibilità di uso di alcune piante – liquirizia Glycyrrhiza glabra, achillea Achillea micrantha, elicriso Helichrysum arenarium per estrarre principi attivi aventi attività antibatterica. È stata valutata la composizione chimica e confrontato le proprietà antibatteriche degli estratti di tre specie di piante - Glycyrrhiza glabra (radice), Achillea micrantha (infiorescenze), Helichrysum arenarium (infiorescenze) - che crescono nella regione di Astrakhan. Sono state inoltre confrontate la composizione chimica e le proprietà antibatteriche dell'e

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12

Crance, Jean-Marc. "Le virus de l'hépatite A : inactivation par des désinfectants et des antiseptiques : inhibition de la multiplication en cultures cellulaires par des substances antivirales." Lyon 1, 1993. http://www.theses.fr/1993LYO1T203.

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13

Oliveira, Jonatas Rafael de [UNESP]. "Ensaio de citotoxicidade de extratos naturais após determinação da concentração microbicida mínima para Staphylococcus spp., Streptococcus mutans e Candida spp." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/95044.

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Made available in DSpace on 2014-06-11T19:27:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-07-14Bitstream added on 2014-06-13T19:56:08Z : No. of bitstreams: 1 oliveira_jr_me_sjc.pdf: 1011850 bytes, checksum: 0914206b09a47699d72d4dc7cfb6450f (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>A proposta deste estudo foi avaliar a atividade antimicrobiana e citotoxicidade dos extratos vegetais de Equisetum arvense L. (cavalinha), Glycyrrhiza glabra L. (alcaçuz), Punica granatum L. (romã) e

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Soares, Aline KÃrcia Alves. "AvaliaÃÃo de seguranÃa e eficÃcia terapÃutica da associaÃÃo de Cassia fistula L, Cassia angustifÃlia Vahl, Tamarindus indica L, Coriandrum sativum L e Glycyrrhiza glabra L em pacientes com constipaÃÃo intestinal." Universidade Federal do CearÃ, 2008. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=3277.

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nÃo hÃ<br>ConstipaÃÃo Ã um problema clÃnico comum que compreende uma constelaÃÃo de sintomas como excessivo esforÃo, fezes duras, sensaÃÃo de evacuaÃÃo incompleta, uso de manobras digitais, ou defecaÃÃo infreqÃente. Seu tratamento emprega medicamentos que aumentem a freqÃÃncia e facilitem as evacuaÃÃes, bem como mudanÃas nos hÃbitos de vida. O objetivo desse estudo foi avaliar seguranÃa, eficÃcia terapÃutica e validar um mÃtodo analÃtico para a gelÃia TamarineÂ, um fitoterÃpico largamente utilizado como laxante, em pacientes com constipaÃÃo intestinal funcional. Foi realizado o perfil cromatog

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15

Soares, Aline Kércia Alves. "Avaliação de segurança e eficácia terapêutica da associação de Cassia fistula L, Cassia angustifólia Vahl, Tamarindus indica L, Coriandrum sativum L e Glycyrrhiza glabra L em pacientes com constipação intestinal." reponame:Repositório Institucional da UFC, 2008. http://www.repositorio.ufc.br/handle/riufc/2686.

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SOARES, Aline Kércia Alves. Avaliação de segurança e eficácia terapêutica da associação de Cassia fistula L, Cassia angustifólia Vahl, Tamarindus indica L, Coriandrum sativum L e Glycyrrhiza glabra L em pacientes com constipação intestinal. 2008. 184 f. Tese (Doutorado em Farmacologia) - Universidade Federal do Ceará. Faculdade de Medicina, Fortaleza, 2008.<br>Submitted by denise santos (denise.santos@ufc.br) on 2012-05-24T12:26:53Z No. of bitstreams: 1 2008_tese_akasoares.pdf: 1080364 bytes, checksum: d56278224795b476210ac767c85583cb (MD5)<br>Approved for entry into archive by Eliene Nascimen

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16

Su, Mai Jane, та 蘇美錚. "Effects of Glycyrrhizae and Glycyrrhizic Acid on Thymus, Testis and Bone Marrow in γ-ray irradiatied Mice". Thesis, 1993. http://ndltd.ncl.edu.tw/handle/20830588164953525951.

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碩士<br>國立清華大學<br>輻射生物研究所<br>81<br>Glycyrrhizae (GL), commonly called licorice, has been used against gastric ulcers and other diseases in Europe and Asia ,and it still occupies an important place in traditional Oriental medicine. Glycyrrhizic acid (GA), the main component of GL have been extensively studied in relation to varied biological activity such as anti-inflammatory activity, direct and indirect antivival activity and interferon inducibility. The effects of GL and GA on the survival

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17

SHENG, TSENG LING, and 曾令生. "The adsorption of copper ion using extracted residue of glycyrrhizae radix." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/70663124254850669846.

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碩士<br>長庚大學<br>化工與材料工程研究所<br>93<br>There is alarge amount of wastewater produced by electroplating and chemical plants every year in Taiwan. Precipitation is a conventional technique to remove heavy metal ions from wastewater. The method will generate another pollutant of sludge, so it is necessary to develop a new technique for separating metal ions. The biosorption was studied by using two types residue of Glycyrrhizae radix, including the residue of supercritical carbon dioxide extraction and non-extracted Glycyrrhizae. Several factors has been investigated, including the relatio

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18

Chang, Tsai-Luan, and 張采鸞. "Glycyrrhizae Radix and Dragon’s blood analysis method development and identification of botanical origin." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/28258455167599269349.

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碩士<br>弘光科技大學<br>化妝品科技研究所<br>99<br>The Chinese medicine of Glycyrrhiza Radix (Leguminosae) root are traditionally use as anti-inflammatory, antioxidant, antiageing properties of mate extracts. Dragon’s blood(Palmae) is an important Chinese tranditional medicine. Dragon's blood were the pharmacological effects of anti-inflammatory, antibacterial, anti-oxidation effect. This study aims to use to establish a simple high performance liquid chromatography analysis of Chinese herbal medicines can shorten the time of the analysis system, combined with liquid chromatography tandem mass spectrometry ana

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Chen, Hui-chun, and 陳彙淳. "The formula design of Ramulus mori, Glycyrrhizae radix, Galla chinensis on skin whitening cosmetics." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/25699293803408922191.

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碩士<br>嘉南藥理科技大學<br>化妝品科技研究所<br>98<br>The aspiration for a whitening, lifted, and toned skin has always been at the Asian’s minds. In Taiwan, many companies have found a substantial and growing market in the skin care products, and therefore, attempted to explore extensively for new product launches. In recent years, the interests in herbal medicinal products, especially in the field of cosmetics and dermatology, have risen enormously. Accordingly, in this study, we aimed to investigate the feasibility of Chinese herbs as cosmetic additives and their manufacturing capacity for advanced/demanding

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20

Chu, Chu-Hsun, and 朱竹薰. "Studies on Identification of Botanical Origin and Component Analysis from Different Source of Glycyrrhizae Radix." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/p6np44.

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碩士<br>國立屏東科技大學<br>農園生產系所<br>105<br>Glycyrrhizae Radix is herbaceous perennial, and its dried root is for medication. There are many active ingredients of triterpenoids and flavonoids in it. This research developed a HPLC method to analyse the flavonoids and triterpenoids in Glycyrrhizae Radix from different species, source and rhizome, that is capable of simultaneous quantitation those compounds. In this study, the HPLC system equipped with a gradient mobile phase composing of 12.5 mM NaH2PO4 (pH2.5) and acetonitrile and an ultraviolet (UV) detectorand operated in the oven controlled at 40°C.

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"Anti-leukemic activities of glycyrrhizin and 18b-glycyrrhetinic acid." 2001. http://library.cuhk.edu.hk/record=b5895877.

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Tsang Yuen-Man.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2001.<br>Includes bibliographical references (leaves 200-218).<br>Abstracts in English and Chinese.<br>ACKNOWLEDGEMENTS --- p.i<br>ABBREVIATIONS --- p.iii<br>ABSTRACT --- p.vii<br>CHINESE ABSTRACT --- p.xi<br>TABLE OF CONTENTS --- p.xiii<br>Chapter CHAPTER 1: --- GENERAL INTRODUCTION<br>Chapter 1.1 --- Hematopoiesis --- p.1<br>Chapter 1.1.1 --- An Overview on Hematopoiesis --- p.1<br>Chapter 1.1.2 --- Role of Cytokines in the Control of Hematopoiesis --- p.4<br>Chapter 1.2 --- Leukemia --- p.5<br>Chapter 1.2.1 --- A

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22

Lin, I.-Hsin, та 林宜信. "Study on Effects of Some Chinese Herbs Including Glycyrrhizae Radix and Polyporus on Cellular Immunocompetence of γ-Ray Irradiated Mice". Thesis, 1996. http://ndltd.ncl.edu.tw/handle/04216310314352911116.

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博士<br>國立清華大學<br>輻射生物研究所<br>84<br>The study was divided into four parts described as in the following: Part Ⅰ. The effects of 137Csγ-ray irradiation (RT) on cellular immunocompentence (CI) of mice were investigated in this part. The dosage of RT, including 5, 50, 100, 200, 300 and 400 cGy. The results revealed that all dosage of 100, 200, 300 and 400 cGy of RT played an evident inhibitory effects on counts of leukocyte (Leu) and its differential counts (DC), the spleen weight (SW) and the

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23

Gau, Yi-Ying, and 高一瑛. "Studies of Chinese Medicines on Asthma I Cervi Parvum Cornu, Panacis Quinquefolii Radix, Scutellariae Radix, Glycyrrhizae Radix and Ma-Xin-Gan-Shi Tang." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/71140892317696454388.

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碩士<br>台北醫學大學<br>生藥學研究所<br>83<br>Allergen-induced asthmatic response is induced by the influx ot inflammatory mediators (e.g. histamine, LTC4) into peribronchial tissues. Recently, asthma, T cell activation in asthma has been proposed, is associated with effect of cytokines (e.g. IL-4 、 IFN-γ). Increased airway epithelial permeability is observed in the pathology of asthma. Therefore, studies of Chinese medicines on asthma were separated into two parts to discuss: first. Pilose Deerhorn (Cervus nippon Temminck) and American Ginseng (Panax quinquefolium Linne) were investigated in an open cli

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Chang, Hung-Chi, and 張宏祺. "Studies on Tissue Culture of Glycyrrhiza uralensis Fischer：Callus Culture of Glycyrrhiza uralensis Fischer and Determination of its Constituents." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/32274112887855504938.

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碩士<br>中國醫藥學院<br>中國藥學研究所<br>91<br>Glycyrrhiza uralensis FISCHER is an important Chinese medicinal plant of the family Leguminosae. The root (Glycyrrhizae Radix or Gan-cao) is one of the oldest and most frequently used medicinal herbs in the history of Chinese herbs. It was first described in the Shen-Nong-Pen-Ts’ao-Chin under the upper category. It is used for reducing body heat and removal of toxic materials, eliminating phlegm and relieving cough and moderating the potency of drugs. Recent studies showed that it demonstrated the properties of anti-ulcer, anti-cancer and anti-AIDS. The most im

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Chen, Chih-Chiang, and 陳志強. "Phytochemical Studies on the Chinese medicine of Glycyrrhiza Radix." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/t94gt5.

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碩士<br>中原大學<br>化學研究所<br>89<br>Abstract The Chinese medicine of Glycyrrhiza Radix. (Glycyrrhiza glabra L.) (Leguminosae) are traditionally use as anti-inflammatory and antidiarrhea. The Chinese medicine of Glycyrrhiza Radix. were extracted with 95 % EtOH . After evaporation of the solvent, the concentrated EtOH extract was partitioned between H2O and EtOAc. By means of various column chromatographic separation , ten compounds were isolated from the EtOAc fraction. By spectral methods , nine Flavonoids including of liquiritigenin (1) , 4’,5 - dihydroxy - 3, 7 - dimethoxy flavone (2) , licoflav

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Holečková, Dana. "Mikroskopie kořenů z různých druhů rodu Glycyrrhiza (Fabaceae). II." Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-306719.

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In the Czech Pharmacopoeia the drug Liquiritiae radix is defined as dried, unpeeled or peeled, whole or cut root and stolons of Glycyrrhiza glabra L. and/or Glycyrrhiza inflata BAT. and/or Glycyrrhiza uralensis FISH. The subject of this thesis was microscopic evaluation of roots and stolons G. glabra, G. pallidiflora, G.echinata and G. uralensis grown in the Czech Republic. Size of calcium oxalate crystals, vessels-wall, diameter width of vessels and number of medulary rays and amount of vessels were detected. By the comparision of the anatomical structure we can differentiate mainly G. pallid

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CAI, DONG-HU, and 蔡東湖. "Pharmacokinetic studies of glycyrrhiza radix and its active principles." Thesis, 1989. http://ndltd.ncl.edu.tw/handle/60024246871938843616.

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Cheel, Horna Jose Carlos. "Profily fenolického obsahu a antivolonoradikálová aktivita kořenů druhů Glycyrrhiza." Doctoral thesis, 2011. http://www.nusl.cz/ntk/nusl-299163.

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7. ABSTRACT 7.1. Phenolic content profiles and free radical-scavenging activity of roots of Glycyrrhiza species In this study, the free radical-scavenging activity of 80% methanolic extracts from G. glabra, G. uralensis, G. echinata, and G. pallidiflora roots was assessed using DPPH free radical and superoxide anion radical scavenging assays. The total contents of phenolics (TP), flavonoids (TF), and tannins (TT) were also measured. From the results, G. glabra showed the highest DPPH radical scavenging activity (DRSA), whereas G. echinata exhibited the lowest values of DRSA. Extracts from G. u

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"Anti-proliferative and differentiation-inducing effects of glycyrrhizin and 18[beta]-glycyrrhetinic acid on neuroblastoma cells in vitro." 2003. http://library.cuhk.edu.hk/record=b5896083.

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Lee Kin-wah.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2003.<br>Includes bibliographical references (leaves 187-203).<br>Abstracts in English and Chinese.<br>ACKNOWLEDGEMENTS --- p.i<br>ABBREVIATIONS --- p.ii<br>ABSTRACT --- p.vi<br>CHINESE ABSTRACT --- p.ix<br>TABLE OF CONTENTS --- p.xii<br>Chapter CHAPTER 1: --- GENERAL INTRODUCTION --- p.1<br>Chapter 1.1 --- Neuroblastoma-An Overview --- p.1<br>Chapter 1.1.1 --- Epidemiology of Neuroblastoma --- p.1<br>Chapter 1.1.2 --- Clinical Presentations of Neuroblastoma --- p.2<br>Chapter 1.1.3 --- Diagnosis of Neuroblastoma ---

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Lan, Wen-Shiaw, and 藍文孝. "Studies on the Antimicrobial Activity of Components from Glycyrrhiza Radix." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/46018856023911725969.

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碩士<br>國立中興大學<br>食品科學系<br>88<br>In this study, antimicrobial spectrum of various solvent extracts, antimicrobial properties of methanol extracts, isolation and purification of antimicrobial components of methanol extracts, structure identification of antimicrobial components and antimicrobial properties of purified or partial purified antimicrobial components from Glycyrrhiza radix cultivated on Mongolia of China were studied. Among the four extracts of licorice, methanol extracts showed the best antimicrobial spectrum which inhibited the growth of ten strains of G(+) and two strains

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Raubenheimer, Carike. "An investigation of compounds isolated from Glycyrrhiza Glabra (Liquorice root)." Diss., 2019. http://hdl.handle.net/10500/26832.

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Introduction: Dark spots appearing on the skin caused by hyperpigmentation results from the action of tyrosinase, an enzyme whose activity leads to the production of the skin pigment melanin. Extracts of the plant Glycyrrhiza glabra, also known as liquorice, are commonly used to treat a range of conditions including skin hyperpigmentation. This study aimed at isolating and identifying compounds in extracts from South African liquorice root and assaying these compounds as to their antioxidant activity, their ability to inhibit the tyrosinase enzyme and their level of cytotoxicity. Methods: The

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CHENG, CHAO-CHUI, and 鄭朝峻. "Glycyrrhiza uralensis Effects on Protein Degradation in HepG-2 Cell." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/ey7c9g.

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碩士<br>國立臺南大學<br>生物科技學系碩士班<br>105<br>Liver is the biggest and important organ for drug metabolism in humans. In previous studies, Ub is increased in liver cancer. Glycyrrhiza uralensis as a Chinese herbal medicine is good for liver. Ubiquitin proteasome pathway and Autophagic lysosomal pathway are two major protein degradation in cells. The mechanism of protein degradation by Glycyrrhiza uralensis is not clear. In this study, the Glycyrrhiza uralensis and Nelumbo nucifera could block ubiquitin-proteasome pathway. The combination of Isoliquiritigenin from Glycyrrhiza uralensis and Hyperoside fro

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Kang, Shih-Pei, та 康詩珮. "Study of Glycyrrhiza uralensis against NF-κB Activation in HepG2 Cells". Thesis, 2011. http://ndltd.ncl.edu.tw/handle/02907314063135520957.

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碩士<br>國立陽明大學<br>傳統醫藥研究所<br>99<br>Liver fibrosis usually results from liver inflammation. When liver is damaged, hepatocytes live in an inflammatory microenvironment. Proinflammatory cytokine, TNF-α stimulates hepatocytes via NF-κB. This study was aimed to screen potential herbs against NF-κB activation in HepG2 cells. Human hepatoma cell lines were used to imitate human hepatocytes in this study. HepG2 cells were stimulated by TNF-α with or without herbs. NF-κB reporter gene assay was used to screen herbs against NF-κB transcription activity. Cell viability was measured by MTT assay. TNF-α-ind

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"Expression of UDP-glucuronosyltransferases (UGTs) in rat liver cells induced by an aqueous extract of licorice root." 2001. http://library.cuhk.edu.hk/record=b6073336.

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Leung Yuet Kin.<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2001.<br>Includes bibliographical references (p. 147-162).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Mode of access: World Wide Web.<br>Abstracts in English and Chinese.

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"Hepatoprotective activity of Glycyrrhiza Uralensis extracts against carcinogens-induced liver tumors in rats." 2014. http://repository.lib.cuhk.edu.hk/en/item/cuhk-1291332.

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Wu, Jiahui.<br>Thesis M.Phil. Chinese University of Hong Kong 2014.<br>Includes bibliographical references (leaves 103-114).<br>Abstracts also in Chinese.<br>Title from PDF title page (viewed on 20, September, 2016).

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Jian, Chong-Shun, and 簡崇訓. "Study of Glycyrrhizic Acid and Azasugars:Synthesis of Glycyrrhizic Acid Derivatives as the Anti-SARS-CoV AgentsSynthesis of Azasugars and the Reactions of Saccharides in Aqueous Solution." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/75805997766943197618.

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碩士<br>國立臺灣大學<br>化學研究所<br>93<br>This thesis consists of two parts. In the first part, we already synthesize glycyrrhizic acid derivatives as the antiviral angents against severe acute respiratory syndrome corona virus (SARS–CoV) agents. In the second part, we synthesize azasugars and explore some reactions of saccharides in I2/NH3 aqueous solution. Glycyrrhizic acid is known to exhibit wide range of biological activities, for example, anti–inflammatory, anti–allergic, anti–dote, antioxidation and anti–tumor activities. However, the mechanism of glycyrrhizic acid in vivo is still unclear. It is

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"Effects of glycyrrhizic acid (GA) on aflatoxin B₁ (AFB₁) induced cytotoxicity." 1999. http://library.cuhk.edu.hk/record=b5890091.

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by Chan Hoi Tak.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1999.<br>Includes bibliographical references (leaves 129-137).<br>Abstracts in English and Chinese.<br>Acknowledgment --- p.i<br>Abstract --- p.ii<br>Abstract (Chinese Version) --- p.iv<br>Abbreviations --- p.vi<br>Contents --- p.viii<br>Chapter CHAPTER ONE --- INTRODUCTION --- p.1<br>Chapter 1.1 --- Aflatoxins --- p.1<br>Chapter 1.1.1 --- AFB1 Metabolism --- p.5<br>Chapter 1.1.2 --- Bioactivation --- p.5<br>Chapter 1.1.3 --- Detoxification --- p.8<br>Chapter 1.1.4 --- Toxicity of AFB1 --- p.9<br>Chapter 1.2 ---

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YANG, MING-HUA, and 楊明華. "Isolation and purification of glycyrrhizin and extraction of antioxidant from licorice residue." Thesis, 1988. http://ndltd.ncl.edu.tw/handle/84488854670896217971.

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"Active fraction of licorice inhibits proliferation of lung cancer cells A549 via inducing cell cycle arrest and apoptosis." 2012. http://library.cuhk.edu.hk/record=b5549045.

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肺癌是導致男性死亡的最常見原因以及是排在乳腺癌和結腸癌之後的導致女性死亡的第三大原因。雖然肺癌如此嚴重，但是如今治疗肺癌仍然是一个挑战。現今對肺癌的治療主要集中在化學治療和靶點藥物治療，但是由於這些治療有著很大的副作用和低治愈率，尋找其他的醫學替代方法十分迫切。甘草是其中最常用的中藥，它常常用作食品工業中的甜味劑。以往的研究表明，甘草具有多種的生物活性。但是甘草提取物對於肺癌的治療卻是十分匱乏的。<br>本論文主要目的是評價甘草提取物以及其中的有效成份對非小型肺癌細胞株A549 的影響，以及其作用的機理。我們的數據表明，甘草的乙酸乙酯（EAL）成份比甘草的乙醇提取物有著比較強的抑制癌細胞的作用。另外，對甘草的五個單體進行的測試中發現lico-3 是最具有抑制肺癌作用的。利用高效液相色譜法對甘草活性成份分析表明，lico-3 是EAL中的其中一個單體。<br>乳酸脫氫酶滲漏（LDH）的檢測結果以及异硫氰酸荧光素-碘化丙啶（FITC-PI）雙染的結果表明，EAL 能夠引起肺癌細胞的凋亡現象而非壞死現象。實驗結果表明由EAL引起的A549細胞凋亡是跟Bcl-2家族及Caspase家族有關係，同時EAL還能夠抑制Akt途徑從而導致細胞的死亡。<br>致肺癌細胞死亡的原因進行進一步研究表明，EAL還能夠引起抑制細胞週期的運作，停留在G2/M 時期。這可能是由於EAL引發了p53與p21的上調

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Wen, Yu Feng, and 溫玉鳳. "The Action of Glycyrrhizin on the Secretion of Interleukin-2 from Jurkat cells." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/50014607778276337772.

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碩士<br>長庚大學<br>基礎醫學研究所<br>93<br>Glycyrrhizin, extracted from the licorice root, is a Chinese traditional herb medicine for 2500 years. Studies showed glycyrrhizin could regulate the specific and non-specific immunity in mice and human beings. In addition, glycyrrhizin inhibits bacterial infection, virus replication, attenuates skin allergy and inactivates B-hepatitis virus. Also, glycyrrhizin has shown to destroy the HIV virus by inhibiting the replication of this virus. Recent study indicated glycyrrhizin prevents the replication of SARS virus in vitro. However, the effect of glycyrrhizin on t

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Tsai, Jai-Jen, and 蔡佳珍. "Study protective effect of glycyrrhizin against total parenteral nutrition induced hepatitis in rats." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/31833594036323114426.

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博士<br>國立陽明大學<br>傳統醫藥研究所<br>104<br>Total parenteral nutrition (TPN) is often complicated by cholestatic hepatitis. The mechanism is unknown till now and no definite therapeutic method is available clinically. Glycyrrhizin, one major constituent of Licorice (Glycyrrhizae radix), has been known to exhibit of anti-infalmmatory, antihepatotoxic, and antioxisative activity. Glycyrrhizin, a major active component, has also not been investigated for its protective effect of glycyrrhizin on choletsasis hepatitis resulting from total parenteral nutrition in detail. The aim of study was to investigate wh

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TASI, YAN-TING, and 蔡嬿婷. "Antiviral Activity of Glycyrrhizic Acid and Its Derivatives Against Dengue Virus Type 2." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/me7rrd.

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"The anti-tumor effects of the Glycyrrhiza uralensis extract on prostate cancer in vivo and in vitro." 2014. http://repository.lib.cuhk.edu.hk/en/item/cuhk-1292034.

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Cao, Lei.<br>Thesis M.Phil. Chinese University of Hong Kong 2014.<br>Includes bibliographical references (leaves 98-118).<br>Abstracts also in Chinese.<br>Title from PDF title page (viewed on 16, December, 2016).

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Zeng, Lu Ping, and 曾律萍. "Influence of Berberine and Glycyrrhizin on Testosterone Secretion from Mice Testicular Leydig TM3 Cell." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/bw4v97.

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Huo, Shuan-wei, and 霍宣瑋. "Anti-enterovirus 71 activity and mechanism of Ge-Gen-Tang and its related pure ingredients of Glycyrrhiza glabra." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/28771379549057553749.

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碩士<br>高雄醫學大學<br>醫學研究所<br>98<br>In 1998, the endemic enterovirus was widely spread over many regions in Taiwan. After the virus caused the public to panic, the Taiwanese government began to aware of the severity of this intestinal virus. Taiwan is a subtropical country ; therefore the infection of endemic enterovirus is usually recurrent and circulate throughout the year, especially in the summer. The serious complications of enterovirus infections are typically caused by enterovirus 71 ( EV 71 ) infection which so far does not have any effective drug, nor vaccine. Therefore, the purpose of th

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CHEN, HENG-RU, та 陳姮如. "甘草(GLYCYRRHIZA-URALENSIS-FISCHER.)抗血小板凝集活性成分之研究". Thesis, 1990. http://ndltd.ncl.edu.tw/handle/63303024869993125727.

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Li, Yu-Ting, and 李雨亭. "Design and Synthesis of Inhibitors againstSARS Coronavirus:Ⅰ alpha-Hydroxy Amide and alpha-KetoamideⅡ Glycyrrhizin Derivatives." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/14948791934852301955.

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碩士<br>國立臺灣大學<br>化學研究所<br>94<br>The aim of this thesis is to discover the antiviral agents against severe acute respiratory syndrome coronavirus (SARS-CoV). This thesis consists of two parts: (i) synthesis of alpha-hydroxy amide and alpha-keto amide derivatives, and (ii) synthesis of glycyrrhetinic acid derivatives. The derivatives of alpha-hydroxy amide and alpha-keto amide, such as 12 and 13 were synthesized, in order to mimic the tetrahedral transition state in the hydrolysis of the peptide substrate catalyzed by the SARS-CoV main protease. The inhibition assays were carried out using a pept

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Chen, Yi-Ting, and 陳怡婷. "Developing analytical methods for glycyrrhizin and its major metabolite glycyrrhetic acid in the aquatic environments." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/77446000740473806350.

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碩士<br>臺灣大學<br>環境工程學研究所<br>98<br>Licorice is one of common traditional Chinese medicines. Glycyrrhizin (GLY), the principle active ingredient of licorice, is the ingredient of antitussive and mucolytic-expectorant for the treatment of chronic hepatitis or allergies. GLY has also been widely used in food additives industry. After oral administration, GLY and its metabolite glycyrrhetic acid (GA) enter the aquatic environment via septic systems. The aims of this research were to: 1) develop analytical method of GLY and GA based on a solid phase extraction (SPE) procedure followed by liquid chroma

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李孟兒. "Molecular Cloning, Protein Expression and Activity Assay of Triterpenoid Tailoring Cytochrome P450 Hydroxylases from Glycyrrhiza glabra and Arabidopsis thaliana." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/69431851545843879479.

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碩士<br>國立交通大學<br>生物科技學系<br>100<br>Triterpene saponins constitute a family of compounds with a triterpene aglycone and sugars structures. They were widely distributed in various species such as food, echinoderm, fungi and plants. Recent researches have demonstrated that triterpene saponins exhibited different biological activities from antiinflammatory, antifungal, antimicrobial, antiparasitic, and antitumor activity. Biosynthetic studies suggested that the structure diversity of triterpene saponin is generated by (1) the cyclization of oxidosqualene to various triterpene skeletons, (2) the subs

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Yen-Chen and 劉晏成. "The inhibitory capabilities of Silibinin and Glycyrrhizin on hepatitis C virus replication and TGF-b1-induced liver fibrosis." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/08766688356748520259.

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碩士<br>中山醫學大學<br>醫學檢驗暨生物技術學系碩士班<br>98<br>Chronic Hepatitis C virus (HCV) infection may lead to the liver fibrosis, cirrhosis and eventually hepatocellular carcinoma. The current standard-of-care for HCV infection is a long-term administration of pegIFNα and ribavirin with only approximately 50% response rate for genotype 1 infected patients while side effects of various severities and viral resistance may lead to treatment failure. Therefore, development of new or auxiliary remedies to improve response rate or alleviate side effects will be of great value. In this study, silibinin and glycyrrhi

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