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Journal articles on the topic 'Glycyrrhizae'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Truong, Minh-Nhut, Quang-Tu Tran, Le Thi Qua, and Lan-Phuong Thi Le. "Investigating the effect of processing conditions on the content of glycyrrhizic acid in licorice (Radix et Rhizoma Glycyrrhizae)." MedPharmRes 8, no. 1 (2024): 52–63. http://dx.doi.org/10.32895/ump.mpr.8.1.6.

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Licorice is the root of Glycyrrhiza uralensis Fisch or Glycyrrhizae inflata L. or Glycyrrhiziae glabra L. It was a familiar medicinal herb in traditional medicine, which was commonly used in two different forms raw licorice (Sinh Cam thao) and honey-fried licorice (Chich Cam thao), with completely different effects. The processing enhanced the impact on the Spleen and Stomach organs and tonified Qi but reduced the bioactivities of clearing heat, antitussive, and detoxifying. The purpose of this study was to propose a processing method that minimizes the degradation of the main bioactive compou

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2

Truong, Minh-Nhut, Quang-Tu Tran, Le Thi Qua, and Lan-Phuong Thi Le. "Investigating the effect of processing conditions on the content of glycyrrhizic acid in licorice (Radix et Rhizoma Glycyrrhizae)." MedPharmRes 8, no. 1 (2024): 52–63. http://dx.doi.org/10.32895/ump.mpr.8.1.52.

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Licorice is the root of Glycyrrhiza uralensis Fisch or Glycyrrhizae inflata L. or Glycyrrhiziae glabra L. It was a familiar medicinal herb in traditional medicine, which was commonly used in two different forms raw licorice (Sinh Cam thao) and honey-fried licorice (Chich Cam thao), with completely different effects. The processing enhanced the impact on the Spleen and Stomach organs and tonified Qi but reduced the bioactivities of clearing heat, antitussive, and detoxifying. The purpose of this study was to propose a processing method that minimizes the degradation of the main bioactive compou

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3

Li, Feifei, Bin Liu, Tong Li, et al. "Review of Constituents and Biological Activities of Triterpene Saponins from Glycyrrhizae Radix et Rhizoma and Its Solubilization Characteristics." Molecules 25, no. 17 (2020): 3904. http://dx.doi.org/10.3390/molecules25173904.

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Glycyrrhizae Radix et Rhizoma is regarded as one of the most popular and commonly used herbal medicines and has been used in traditional Chinese medicine (TCM) prescriptions for over 2000 years. Pentacyclic triterpene saponins are common secondary metabolites in these plants, which are synthesized via the isoprenoid pathway to produce a hydrophobic triterpenoid aglycone containing a hydrophilic sugar chain. This paper systematically summarizes the chemical structures of triterpene saponins in Glycyrrhizae Radix et Rhizoma and reviews and updates their main biological activities studies. Furthe

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4

He, Ming-Feng, Jian-Hui Liang, Yan-Ni Shen, et al. "Glycyrrhizin Inhibits SARS-CoV-2 Entry into Cells by Targeting ACE2." Life 12, no. 11 (2022): 1706. http://dx.doi.org/10.3390/life12111706.

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Coronavirus Disease 2019 (COVID-19) is a highly infectious and pathogenic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Early in this epidemic, the herbal formulas used in traditional Chinese medicine (TCM) were widely used for the treatment of COVID-19 in China. According to Venn diagram analysis, we found that Glycyrrhizae Radix et Rhizoma is a frequent herb in TCM formulas against COVID-19. The extract of Glycyrrhizae Radix et Rhizoma exhibits an anti-SARS-CoV-2 replication activity in vitro, but its pharmacological mechanism remains unclear. We here de

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Ni, Lulu, Ping Miao, Jian Jiang, et al. "Glycyrrhiza uralensis promote the metabolism of toxic components of Aconitum carmichaeli by CYP3A and alleviate the development of chronic heart failure." PLOS ONE 17, no. 6 (2022): e0270069. http://dx.doi.org/10.1371/journal.pone.0270069.

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Aconitum, as "the first drug of choice for invigorating Yang and saving lives", has been widely used for the treatment of heart failure. However, toxic components of Aconitum can easily lead to serious arrhythmia, even death (Y. CT., 2009; Zhang XM., 2018). In this study, a High Performance Liquid Chromatography (HPLC) method for the determination of aconitine (AC), mesaconitine (MA) and hypaconitine (HA) was established; The effect of Glycyrrhiza on CYP3A1 / 2 mRNA expression was detected by RT-PCR; SD rats were given Aconitum and compatibility of Glycyrrhizae and Aconitum by gavage respectiv

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6

Langer, Dominik, Beata Czarczynska-Goslinska, and Tomasz Goslinski. "Glycyrrhetinic acid and its derivatives in infectious diseases." Current Issues in Pharmacy and Medical Sciences 29, no. 3 (2016): 118–23. http://dx.doi.org/10.1515/cipms-2016-0024.

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AbstractIntroduction. Licorice or liquorice (Glycyrrhiza glabra, Leguminosae) is a perennial plant naturally occurring or cultivated in Europe and Asia. It was appreciated by many ancient cultures, and was employed within Arabic medicine and (beginning in the Middle Ages) in Europe folk medicine as a remedy for many diseases. Currently, the sweet flavoured root of this plant – Radix Glycyrrhizae (Liquirtiae), is widely taken for the treating of various upper respiratory tract diseases, as well as for gastric ulcer disease. It is also utilized as a sweetening and flavouring agent in the food, t

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7

Han, You Jin, Bitna Kang, Eun-Ju Yang, Min-Koo Choi, and Im-Sook Song. "Simultaneous Determination and Pharmacokinetic Characterization of Glycyrrhizin, Isoliquiritigenin, Liquiritigenin, and Liquiritin in Rat Plasma Following Oral Administration of Glycyrrhizae Radix Extract." Molecules 24, no. 9 (2019): 1816. http://dx.doi.org/10.3390/molecules24091816.

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Glycyrrhizae Radix is widely used as herbal medicine and is effective against inflammation, various cancers, and digestive disorders. We aimed to develop a sensitive and simultaneous analytical method for detecting glycyrrhizin, isoliquiritigenin, liquiritigenin, and liquiritin, the four marker components of Glycyrrhizae Radix extract (GRE), in rat plasma using liquid chromatography-tandem mass spectrometry and to apply this analytical method to pharmacokinetic studies. Retention times for glycyrrhizin, isoliquiritigenin, liquiritigenin, and liquiritin were 7.8 min, 4.1 min, 3.1 min, and 2.0 m

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8

Cao, Chengliang, Yong Sun, Bo Wu, et al. "Actinophytocola glycyrrhizae sp. nov. isolated from the rhizosphere of Glycyrrhiza inflata." International Journal of Systematic and Evolutionary Microbiology 68, no. 8 (2018): 2504–8. http://dx.doi.org/10.1099/ijsem.0.002864.

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9

Guo, Dongqi, Xiuxiu Yin, Huan Cheng, Xingqian Ye, and Jianle Chen. "Evaluating Physicochemical and Sensory Properties of Functional Yogurt Supplemented with Glycyrrhiza Polysaccharide as Potential Replacement for Gelatin." Agriculture 12, no. 9 (2022): 1289. http://dx.doi.org/10.3390/agriculture12091289.

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Glycyrrhiza is a well-known plant resource used for the production of extractum-glycyrrhizae; however, large amounts of Glycyrrhiza residues containing polysaccharides are produced, and these have not been well utilized until now. The aim of this study was to evaluate the Glycyrrhiza polysaccharides obtained from Glycyrrhiza residues as a potential gelatin replacer in yogurt. The incorporation of Glycyrrhiza polysaccharide (GP) at different concentrations accelerated the growth of lactic acid bacteria. Similar to the effect of adding gelatin (GE), GP could suitably improve the water-holding ca

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10

Lin, I.-Hsin, Dou-Mong Hau, Mei-Jane Su, and Wang-Chi Chena. "Effects of Glycyrrhizae and Glycyrrhizic Acid on Radiation Injury in Mice." American Journal of Chinese Medicine 24, no. 03n04 (1996): 279–88. http://dx.doi.org/10.1142/s0192415x96000347.

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The effects of Glycyrrhizae (GL) and Glycyrrhizic acid (GA) on promoting the recovery of mice from radiation injury were investigated. Two hundred ICR strain male mice, 6-8 weeks old, were randomly divided into four groups. Group A was the normal control. Group B, the experimental control, was treated with 4 Gy γ-ray irradiation. Groups C and D, the experimental groups, were treated with 500 m/g of GL (oral administration) and 5 m/g body weight of GA (i.p.), respectively, for ten days after γ-ray irradiation. Eight mice in each group were sacrificed on days 5, 12, 26 and 33 post irradiation to

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11

Duan, Lei, Li-Na Han, Yotsawate Sirichamorn, et al. "Proposal to recognise the tribes Adinobotryeae and Glycyrrhizeae (Leguminosae subfamily Papilionoideae) based on chloroplast phylogenomic evidence." PhytoKeys 181 (September 2, 2021): 65–77. http://dx.doi.org/10.3897/phytokeys.181.71259.

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Within the legume family, the taxonomic status of subtribe Glycyrrhizinae of tribe Galegeae and of the genus Adinobotrys has been re-assessed. Based on genome skimming data, we conducted phylogenomic analyses of the inverted repeat-lacking clade within subfamily Papilionoideae. The results support the sister relationship between Glycyrrhizeae and Adinobotrys. Glycyrrhizeae is resurrected based on Glycyrrhiza and Glycyrrhizopsis, and a new tribe, Adinobotryeae, is proposed to accommodate Adinobotrys.

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Duan, Lei, Li-Na Han, Yotsawate Sirichamorn, et al. "Proposal to recognise the tribes Adinobotryeae and Glycyrrhizeae (Leguminosae subfamily Papilionoideae) based on chloroplast phylogenomic evidence." PhytoKeys 181 (September 2, 2021): 65–77. https://doi.org/10.3897/phytokeys.181.71259.

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Within the legume family, the taxonomic status of subtribe Glycyrrhizinae of tribe Galegeae and of the genus Adinobotrys has been re-assessed. Based on genome skimming data, we conducted phylogenomic analyses of the inverted repeat-lacking clade within subfamily Papilionoideae. The results support the sister relationship between Glycyrrhizeae and Adinobotrys. Glycyrrhizeae is resurrected based on Glycyrrhiza and Glycyrrhizopsis, and a new tribe, Adinobotryeae, is proposed to accommodate Adinobotrys.

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13

Sharifi-Rad, Javad, Cristina Quispe, Jesús Herrera-Bravo, et al. "Glycyrrhiza Genus: Enlightening Phytochemical Components for Pharmacological and Health-Promoting Abilities." Oxidative Medicine and Cellular Longevity 2021 (July 24, 2021): 1–20. http://dx.doi.org/10.1155/2021/7571132.

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The Glycyrrhiza genus, generally well-known as licorice, is broadly used for food and medicinal purposes around the globe. The genus encompasses a rich pool of bioactive molecules including triterpene saponins (e.g., glycyrrhizin) and flavonoids (e.g., liquiritigenin, liquiritin). This genus is being increasingly exploited for its biological effects such as antioxidant, antibacterial, antifungal, anti-inflammatory, antiproliferative, and cytotoxic activities. The species Glycyrrhiza glabra L. and the compound glycyrrhizin (glycyrrhizic acid) have been studied immensely for their effect on huma

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14

Wu, Huifei, Wenxia Zhang, Hui Lin, Qiuming Ye, Jiayin Guo, and Shijian Quan. "The Pseudotargeted Metabolomics Study on the Toxicity of Fuzi Using Ultraperformance Liquid Chromatography Tandem Mass Spectrometry." Evidence-Based Complementary and Alternative Medicine 2022 (September 13, 2022): 1–9. http://dx.doi.org/10.1155/2022/6539675.

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Fuzi is commonly used in traditional Chinese medicine. Clinical Fuzi poisoning cases have frequently been reported. Glycyrrhizae Radix is often used to alleviate Fuzi’s toxicity. However, the poisoning mechanism of Fuzi and the detoxication mechanism of Glycyrrhizae Radix are still not clear. We identified the chemical components of Fuzi at different decoction times (0.5, 1, 2, 4, and 6 h) using ultrahigh performance liquid chromatography quadrupole time-of-flight mass spectrometry. A total of 35 compounds were detected in the Fuzi decoction, including diester alkaloids, monoester alkaloids, a

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15

Zhang, Guo-qing, Song-gang Ji, Yi-feng Chai, Yu-tian Wu, and Xue-ping Yin. "Determination of glycyrrhizin inRadix glycyrrhizae and its preparations by capillary zone electrophoresis." Biomedical Chromatography 13, no. 6 (1999): 407–9. http://dx.doi.org/10.1002/(sici)1099-0801(199910)13:6<407::aid-bmc901>3.0.co;2-o.

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16

Nakagawa, Takako, Takako Yokozawa, Young Ae Kim, Ki Sung Kang, and Takashi Tanaka. "Activity of Wen-Pi-Tang, and Purified Constituents of Rhei Rhizoma and Glycyrrhizae Radix against Glucose-Mediated Protein Damage." American Journal of Chinese Medicine 33, no. 05 (2005): 817–29. http://dx.doi.org/10.1142/s0192415x05003375.

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Wen-Pi-Tang, an Oriental medical prescription composed of Rhei Rhizoma, Ginseng Radix, Aconiti Tuber, Zingiberis Rhizoma and Glycyrrhizae Radix, is used clinically as a medicine to treat renal failure. This study was conducted to examine the inhibitory activity of the five crude drug components of Wen-Pi-Tang and several pure compounds isolated from Rhei Rhizoma and Glycyrrhizae Radix against the protein glycation reaction. Rhei Rhizoma exerted the most potent activity, Zingiberis Rhizoma and Glycyrrhizae Radix showed relatively moderate activity, whereas Aconiti Tuber and Ginseng Radix showed

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17

Zhu, Shu, Reiko Sugiyama, Javzan Batkhuu, Chinbat Sanchir, Kun Zou, and Katsuko Komatsu. "Survey of Glycyrrhizae Radix resources in Mongolia: chemical assessment of the underground part of Glycyrrhiza uralensis and comparison with Chinese Glycyrrhizea Radix." Journal of Natural Medicines 63, no. 2 (2008): 137–46. http://dx.doi.org/10.1007/s11418-008-0303-7.

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18

Shi, Ling-Zhu, Xi Chen, Hui-Hui Cao, et al. "N-butanol Extract of Glycyrrhizae Radix et Rhizoma Inhibits Dengue Virus through Targeting Envelope Protein." Pharmaceuticals 16, no. 2 (2023): 263. http://dx.doi.org/10.3390/ph16020263.

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Background: At present, about half of the world’s population is at risk of being infected with dengue virus (DENV). However, there are no specific drugs to prevent or treat DENV infection. Glycyrrhizae Radix et Rhizome, a well-known traditional Chinese medicine, performs multiple pharmacological activities, including exerting antiviral effects. The aim of this study was to investigate the anti-DENV effects of n-butanol extract from Glycyrrhizae Radix et Rhizome (GRE). Methods: Compounds analysis of GRE was conducted via ultra-performance liquid chromatography/tandem mass spectrometry (UHPLC-MS

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Honda, Hiroe, Yoshinori Nagai, Kensuke Miyake, and Kiyoshi Takatsu. "Molecular basis of regulatory effect of medicinal plant components on the innate immune response through TLR4 signaling (89.1)." Journal of Immunology 184, no. 1_Supplement (2010): 89.1. http://dx.doi.org/10.4049/jimmunol.184.supp.89.1.

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Abstract The mammalian immune system consists of two branches: innate and acquired immunity. The innate immune system recognizes microorganisms via germline-encoded pathogen-associated pattern recognition receptors (PARRs) and plays a role in the first line of host defense against pathogens. Toll-like receptors (TLRs) belong to PARRs play indispensable roles for both innate and acquired immunity. One-third of the current top 20 drugs on the market are plant derived. Interestingly, anticancer drug Paclitaxel from Pacific yew tree interacts with human MD-2 and activates dendritic cells through T

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20

Zou, Yu Hong, Qiu Xia Han, and Lin Guo. "Study on Extraction of Total Flavonoids from Licorice with Ultrasonic Assistance and Antioxidant Activity." Advanced Materials Research 550-553 (July 2012): 1629–32. http://dx.doi.org/10.4028/www.scientific.net/amr.550-553.1629.

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To optimize the extraction process of total flavonoids from RADIX RHIZOMA GLYCYRRHIZAE and Study on the Antioxidant Activity. Total flavonoids were extracted from RADIX RHIZOMA GLYCYRRHIZAE with ethanol by ultrasonic-assisted method, whose extraction process was optimized by orthogonal test design.The scavenging effect of pumpkin polysaccharide on OH and O2-were studied by salicylic acid and pyrogallic acid method. The optimum extraction process was as follows: ethanol concentration of 75%, solid-liquid ratio of 1:25,ultrasonic power of 350 W and ultrasonic duration of 25 min.Under the above c

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Miyazawa, Mitsuo, and Hiromu Kameoka. "Volatile flavour components of glycyrrhizae radix (Glycyrrhiza glabra L. var.glandulifera Regel et Herder) from China." Flavour and Fragrance Journal 5, no. 3 (1990): 157–60. http://dx.doi.org/10.1002/ffj.2730050305.

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Ma, Li, Yangyang Zhao, Xiaoxue Zhang, Tianfeng Liu, Fei Han, and Ran Yin. "Characterization of the global metabolic profile of liquiritin in rat plasma, urine, bile and feces based on UHPLC-FT-ICR MS." RSC Advances 8, no. 11 (2018): 5945–52. http://dx.doi.org/10.1039/c7ra12529a.

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Yan, Tianying, Long Duan, Xiaopan Chen, Pan Gao, and Wei Xu. "Application and interpretation of deep learning methods for the geographical origin identification of Radix Glycyrrhizae using hyperspectral imaging." RSC Advances 10, no. 68 (2020): 41936–45. http://dx.doi.org/10.1039/d0ra06925f.

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24

Jin, Rui, Ling Ling Wan, Toshimi Mitsuishi, et al. "Effect of Shi-Ka-Ron and Chinese Herbs on Cytokine Production of Macrophage in Immunocompromised Mice." American Journal of Chinese Medicine 22, no. 03n04 (1994): 255–66. http://dx.doi.org/10.1142/s0192415x94000310.

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Shi-Ka-Ron is a prescription composed of 8 crude extracts of Chinese herbs. It reduces suppression of cytokine production by peritoneal macrophages in mice Immunocompromised by the anti-tumor agent, cyclophosphamide (CY), in vivo. Although it dose not increase IL-1 production in vitro, it enhances TNF production. We found that Ginseng radix, Lithospermi radix, Astragli radix and Glycyrrhizae radix somewhat reduced suppression of cytokine production in CY treated macrophages. Especially, Glycyrrhizae radix shows an active immune response both in vivo and in vitro. Our results suggested that the

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Tykhonenko, Yu Ya, and L. P. Vakarenko. "First records of Uromyces glycyrrhizae (Pucciniales) in Ukraine." Ukrainian Botanical Journal 75, no. 2 (2018): 187–90. http://dx.doi.org/10.15407/ukrbotj75.02.187.

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Lee, Young-Sook, and Jeong-Dae Jang. "The Extract of the Glycyrrhizin from Glycyrrhizae Radix and Antibacterial Activity of the Treated Fabrics." Fashion & Textile Research Journal 15, no. 2 (2013): 286–93. http://dx.doi.org/10.5805/sfti.2013.15.2.286.

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27

Lim, HK, ME Baek, Y. Jo, and JH Kwon. "Microwave-assisted simultaneous extraction of liquiritigenin and glycyrrhizic acid from Licorice (Glycyrrhizae radix et Rhizoma)." Planta Medica 81, S 01 (2016): S1—S381. http://dx.doi.org/10.1055/s-0036-1596442.

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Maria Pia, Gatta Daniela, Franceschelli Sara, Felaco Mario, and Speranza Lorenza. "Biological Effects of Licochalcones." Mini-Reviews in Medicinal Chemistry 19, no. 8 (2019): 647–56. http://dx.doi.org/10.2174/1389557518666180601095420.

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Medicinal plants and their natural bioactive molecules, are evaluated as the foundation for health preservation and care of humanity. The licorice root, known as “Radix Glycyrrhizae”, is a perennial plant that comes from Mediterranean countries, central to southern Russia, Asia, Turkey, Iraq and Iran. The licorice root has been used in traditional Chinese medicines for centuries and has been defined as &quot;the progenitor of herbs&quot;. The name &#039;Licorice&#039; is derived from the ancient Greek word Glukurrhiza, meaning &#039;sweet root&#039;. It consists of appr

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Nomura, Toshihito, Masaya Fukushi, Kosuke Oda, Akifumi Higashiura, Takashi Irie, and Takemasa Sakaguchi. "Effects of Traditional Kampo Drugs and Their Constituent Crude Drugs on Influenza Virus Replication In Vitro: Suppression of Viral Protein Synthesis by Glycyrrhizae Radix." Evidence-Based Complementary and Alternative Medicine 2019 (December 3, 2019): 1–12. http://dx.doi.org/10.1155/2019/3230906.

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An influenza virus epidemic is an important issue in public hygiene, and continuous development on an effective drug is required. Kampo medicine is a traditional medicine that is used clinically for treatment of various diseases in Japan and other East Asian countries. We evaluated the effects of the Kampo drugs maoto, kakkonto, senkyuchachosan, jinkokato, and bakumondoto, which are prescribed for treatment of respiratory symptoms including symptoms caused by influenza, on influenza virus replication in cultured cells. Culture media of influenza virus-infected MDCK(+) cells were tested for hem

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Saini, Mohit, and Jitender K. Malik. "In-Silico Validation of Glycyrrhizin against Proinflammatory Mediator COX-2: Anti-Proliferative Potential." South Asian Research Journal of Pharmaceutical Sciences 5, no. 05 (2023): 206–12. http://dx.doi.org/10.36346/sarjps.2023.v05i05.004.

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Background: Licorice's scientific name is Glycyrrhiza glabra. It is a well-known medicinal plant that grows in numerous locations throughout the world. It is one of the most ancient and widely utilised plants and has been used for a very long period in both western and eastern nations. The primary source of the triterpenoid saponin, glycyrrhizic acid (also known as glycyrrhizin), which is a sweeter component and around 50 times sweeter than sugar, was the Glycyrrhiza glabra (Fabaceae) root. Glycyrrhetinic acid has been found as the chemical constituent of glycyrrhizin. Aim: The current work so

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Wang, Ruizhong, Yurong Zhang, Junjun Mao, Shaoli Liang, Yan Wu, and Lin Chen. "Study of Quality Standards of Xiao’er Qingre Enema Preparation in Hospitals." Journal of Clinical and Nursing Research 8, no. 1 (2024): 125–32. http://dx.doi.org/10.26689/jcnr.v8i1.5516.

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Objective: To establish the quality standards for the preparation of Xiao’er Qingre enema in hospitals. Method:Thin-layer chromatography (TLC) was used to identify Radix Isatidis and Glycyrrhizae in the prescription. The content of (R,S)-Goitrin was determined by high-performance liquid chromatography (HPLC). Results: In TLC identification, there was no interference between the negative controls of Radix Isatidis and glycyrrhizae, and the spots were well-separated. The HPLC results of (R,S)-Goitrin showed a good linear relationship between the peak area and concentration within the range of 0.

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Chan, Anthony S. L., Haihong Pang, Eric C. H. Yip, Yun K. Tam та Yung H. Wong. "The Aqueous Extract of Radix Glycyrrhizae Stimulates Mitogen-Activated Protein Kinases and Nuclear Factor-κB in Jurkat T-Cells and THP-1 Monocytic Cells". American Journal of Chinese Medicine 34, № 02 (2006): 263–78. http://dx.doi.org/10.1142/s0192415x06003813.

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Radix Glycyrrhizae (RG) is a medicinal herb extensively utilized in numerous Chinese medical formulae for coordinating the actions of various components in the recipes and strengthening the body functions. In this report, we demonstrate that the aqueous extract of Radix Glycyrrhizae is capable of stimulating the c-Jun N-terminal kinase and p38 subgroups of mitogen-activated protein kinases (MAPKs), and the nuclear factor-κB ( NF κ B ) in Jurkat T-lymphocytes. The activation magnitudes of MAPKs and NF κ B were dose-dependent ( EC 50 ≈ 1 mg/ml ) and time-dependent (maximal around 15–30 minutes).

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Kuo, Chien-hsin, Heung Ko, and Seon-mi Shin. "Comparison of Herbs in Prescription Composition of Consumptive Disease and Internal Injury in Donguibogam Through Network Analysis." Journal of Internal Korean Medicine 44, no. 1 (2023): 35–52. http://dx.doi.org/10.22246/jikm.2023.44.1.35.

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Objective: Internal injuries and consumptive disease have different causes, yet they can affect each other. The relationship and combination of prescription drugs in the clinical practice of internal injuries and consumptive disease were analyzed for various diseases of “Donguibogam” through network analysis.Methods: The prescriptions used in consumptive disease and internal injury were established by conducting a full survey on the papers extracted from Donguibogam. The R version 4.0.3 (2020-10-10) and the igraph and arules package were used to perform network analysis and association rule re

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SAGARA, KAZUHIKO, YUJI ITO, TOSHIYUKI OSHIMA, MASANARI KAWAURA, and TETSUO MISAKI. "Application of ion-pair high-performance liquid chromatography to the analysis of glycyrrhizin in glycyrrhizae radix." CHEMICAL & PHARMACEUTICAL BULLETIN 33, no. 12 (1985): 5364–68. http://dx.doi.org/10.1248/cpb.33.5364.

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35

Tagami, Takaomi, Keiji Kajimura, Katsuhiro Yamasaki, Yoshiyuki Sawabe, Shuzo Taguchi, and Syozo Iwagami. "Determination of Organochlorine Pesticides in Glycyrrhizae Radix." JOURNAL OF HEALTH SCIENCE 54, no. 6 (2008): 665–70. http://dx.doi.org/10.1248/jhs.54.665.

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Zhao, Songsong, Ying Zhao, and Zheng Xiang. "A novel symmetrical cyclooctenone from Radix Glycyrrhizae." Natural Product Research 35, no. 1 (2019): 88–91. http://dx.doi.org/10.1080/14786419.2019.1614580.

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37

&NA;. "Glycyrrhiza/glycyrrhizin." Reactions Weekly &NA;, no. 1309 (2010): 22. http://dx.doi.org/10.2165/00128415-201013090-00070.

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Zhang, Liying, Shihan Qin, Sunv Tang, et al. "Qualitative Analysis of Multiple Phytochemical Compounds in Tojapride Based on UHPLC Q-Exactive Orbitrap Mass Spectrometry." Molecules 27, no. 19 (2022): 6639. http://dx.doi.org/10.3390/molecules27196639.

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Tojapride is composed of Caulis Perillae, Rhizoma Cyperi, Radix Glycyrrhizae, Citrus aurantium L., Coptis chinensis Franch, Pericarpium Citri Reticulatae, Reynoutria japonica Houtt, Tetradium ruticarpum, and Cleistocactus sepium. It has the effects of inhibiting gastric acid and relieving pain. It is clinically used for treating gastroesophageal reflux disease. To further study the pharmacodynamic properties of Tojapride, the systematic characterization of the chemical constituents in Tojapride was investigated using ultra-performance liquid chromatography with Q-Exactive Orbitrap mass spectro

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Nose, Mitsuhiko, Momoka Tada, Asuka Kato, et al. "Effect of Schisandrae Fructus on glycyrrhizin content in Kampo extracts containing Glycyrrhizae Radix used clinically in Japan." Journal of Natural Medicines 73, no. 4 (2019): 834–40. http://dx.doi.org/10.1007/s11418-019-01325-4.

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Rehman, Muneeb U., Adil Farooq, Rayeesa Ali, et al. "Preclinical Evidence for the Pharmacological Actions of Glycyrrhizic Acid: A Comprehensive Review." Current Drug Metabolism 21, no. 6 (2020): 436–65. http://dx.doi.org/10.2174/1389200221666200620204914.

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Glycyrrhiza glabra L. (Family: Fabaceae) is one of the important traditional medicinal plant used extensively in folk medicine. It is known for its ethnopharmacological value in curing a wide variety of ailments. Glycyrrhizin, an active compound of G. glabra, possesses anti-inflammatory activity due to which it is mostly used in traditional herbal medicine for the treatment and management of chronic diseases. The present review is focused extensively on the pharmacology, pharmacokinetics, toxicology, and potential effects of Glycyrrhizic Acid (GA). A thorough literature survey was conducted to

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Lee, Young-Sook, and Jeong-Dae Jang. "Dyeing of Cotton fabrics by Glycyrrhizae Radix Extract." Textile Coloration and Finishing 22, no. 1 (2010): 21–27. http://dx.doi.org/10.5764/tcf.2010.22.1.021.

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Cho, So-Yean, Seung-Ho Lee, Ji-Young Choi, et al. "Antigastritic Effect of Carbenoxolone Disodium from Glycyrrhizae Radix." Toxicological Research 23, no. 2 (2007): 165–72. http://dx.doi.org/10.5487/tr.2007.23.2.165.

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Fu, Naiwu, and Zhaoyang Liu. "Antipromoting, antimutagenic and antioxidant action of glycyrrhizae flavonoids." Chinese Journal of Cancer Research 7, no. 3 (1995): 163–67. http://dx.doi.org/10.1007/bf03023467.

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Li, Bao-Xin, Peng-Yue Li, Li-Xia Hao, et al. "Identification and Determination of the Major Constituents in Xie-Bai-San by Ultra-performance Liquid Chromatography–Mass Spectrometry." World Journal of Traditional Chinese Medicine 10, no. 3 (2024): 334–46. http://dx.doi.org/10.4103/wjtcm.wjtcm_50_23.

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Objective: The ancient classical Chinese formulation, Xie-Bai-San (XBS), was studied qualitatively and quantitatively, and its main components were characterized. Materials and Methods: The chemical compounds in XBS were identified using a combination of ultra-performance liquid chromatography-quadrupole-Orbitrap mass spectrometry and molecular networking (MN) analysis. In addition, a multiple reaction monitoring (MRM) quantification method was established using ultra-high-performance liquid chromatography–triple quadrupole mass spectrometry. Mulberroside A, kukoamine B, liquiritin, and glycyr

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Nose, Mitsuhiko, Momoka Tada, Rika Kojima, et al. "Comparison of glycyrrhizin content in 25 major kinds of Kampo extracts containing Glycyrrhizae Radix used clinically in Japan." Journal of Natural Medicines 71, no. 4 (2017): 711–22. http://dx.doi.org/10.1007/s11418-017-1101-x.

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Putri, Tasya Ellyana. "Potensi Akar Manis sebagai Pengobatan Infeksi Covid-19." Jurnal Penelitian Perawat Profesional 3, no. 3 (2021): 525–30. http://dx.doi.org/10.37287/jppp.v3i3.539.

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Infeksi COVID-19 merupakan penyakit yang disebabkan oleh Virus RNA Single Stranded yaitu Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV2). Tingkat penularan virus yang cepat dari manusia ke manusia menyebabkan pandemi. Tujuan dilakukannya literature review ini adalah untuk mengetahui potensi dari akar manis sebagai pengobatan infeksi COVID-19. Penulisan artikel ini menggunakan metode literature review. Artikel ini terbentuk atas informasi yang didapatkan dari 19 artikel dari jurnal internasional dan nasional yang didapatkan dari hasil literature searching dari database Pubmed, NCBI

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Thu, Vu Thi, Ngo Thi Hai Yen, and Nguyen Thi Ha Ly. "Liquiritin from Radix Glycyrrhizae Protects Cardiac Mitochondria from Hypoxia/Reoxygenation Damage." Journal of Analytical Methods in Chemistry 2021 (August 6, 2021): 1–11. http://dx.doi.org/10.1155/2021/1857464.

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Aims. The purpose of this study was to evaluate the protective effect of liquiritin (LIQ) from Radix Glycyrrhizae on cardiac mitochondria against hypoxia/reoxygenation (HR) injury. Methods. H9C2 cells were subject to the HR model. LIQ purified from Radix Glycyrrhizae (purity > 95%) was administrated to reoxygenation period. Cell viability, mitochondrial mass, mitochondrial membrane potential, reactive oxygen species, and mitochondrial Ca2⁺ level were then assessed by using Cell Counting kit-8 and suitable fluorescence probe kits. Results. LIQ administration remarkably reduced the rate of HR

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Yang, X. "Dose-response patterns of Radix Glycyrrhizae in Shanghan Lun." Journal of Chinese Integrative Medicine 7, no. 3 (2009): 268–72. http://dx.doi.org/10.3736/jcim20090313.

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Yang, Ming, Yi Jin, and LiPing Yang. "A systematic summary of natural compounds in Radix Glycyrrhizae." Traditional Medicine Research 3, no. 2 (2018): 82–94. http://dx.doi.org/10.53388/tmr201810067.

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Aida, Kaoru, Masato Tawata, Hideo Shindo, et al. "Isoliquiritigenin: A New Aldose Reductase Inhibitor from Glycyrrhizae Radix." Planta Medica 56, no. 03 (1990): 254–58. http://dx.doi.org/10.1055/s-2006-960950.

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