Academic literature on the topic 'Glyoxylate cycle'

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Journal articles on the topic "Glyoxylate cycle"

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Bruce, David. "Glyoxylate cycle as drug target?" Genome Biology 2 (2001): spotlight—20010710–01. http://dx.doi.org/10.1186/gb-spotlight-20010710-01.

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Yokota, A., S. Haga, and S. Kitaoka. "Purification and some properties of glyoxylate reductase (NADP+) and its functional location in mitochondria in Euglena gracilis z." Biochemical Journal 227, no. 1 (1985): 211–16. http://dx.doi.org/10.1042/bj2270211.

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Euglena mitochondria contain both glyoxylate reductase (NADP+) and glycollate dehydrogenase to constitute the glycollate-glyoxylate cycle [Yokota & Kitaoka (1979) Biochem. J. 184, 189-192]. Euglena glyoxylate reductase (NADP+) was purified and its submitochondrial location was determined in order to elucidate the cycle. The purified glyoxylate reductase was homogeneous on polyacrylamide-gel electrophoresis. Difference spectra of the purified enzyme revealed that the enzyme was a flavin enzyme. The Mr of the enzyme was 82 000. The enzyme was specific for NADPH, with an apparent Km of 3.9 mi
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Dunn, M. F., J. A. Ramírez-Trujillo, and I. Hernández-Lucas. "Major roles of isocitrate lyase and malate synthase in bacterial and fungal pathogenesis." Microbiology 155, no. 10 (2009): 3166–75. http://dx.doi.org/10.1099/mic.0.030858-0.

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The glyoxylate cycle is an anaplerotic pathway of the tricarboxylic acid (TCA) cycle that allows growth on C2 compounds by bypassing the CO2-generating steps of the TCA cycle. The unique enzymes of this route are isocitrate lyase (ICL) and malate synthase (MS). ICL cleaves isocitrate to glyoxylate and succinate, and MS converts glyoxylate and acetyl-CoA to malate. The end products of the bypass can be used for gluconeogenesis and other biosynthetic processes. The glyoxylate cycle occurs in Eukarya, Bacteria and Archaea. Recent studies of ICL- and MS-deficient strains as well as proteomic and t
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Gonçalves, Itamar Luís, Albanin Aparecida Mielniczki-Pereira, Ana Claudia Piovezan Borges, and Alice Teresa Valduga. "Metabolic modeling and comparative biochemistry in glyoxylate cycle." Acta Scientiarum. Biological Sciences 38, no. 1 (2016): 1. http://dx.doi.org/10.4025/actascibiolsci.v38i1.24597.

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Glyoxylate cycle in fatty acid catabolism enhances net production of oxaloacetate, a substrate for gluconeogenesis, in certain bacteria, invertebrates and oilseed in the growth stage. A theoretical model was developed to calculate ATP amount produced in each step of the catabolic pathway, taking into account the fatty acid’s hydrocarbon chain size. Results showed a decrease in energy efficiency in glyoxylate cycle when compared to animal metabolism. Although the glyoxylate cycle provides evolutionary adaptations, it determines a smaller amount of energy produced per carbon atom when compared t
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Korotkova, Natalia, Mary E. Lidstrom, and Ludmila Chistoserdova. "Identification of Genes Involved in the Glyoxylate Regeneration Cycle in Methylobacterium extorquens AM1, Including Two New Genes, meaC and meaD." Journal of Bacteriology 187, no. 4 (2005): 1523–26. http://dx.doi.org/10.1128/jb.187.4.1523-1526.2005.

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ABSTRACT The glyoxylate regeneration cycle (GRC) operates in serine cycle methylotrophs to effect the net conversion of acetyl coenzyme A to glyoxylate. Mutants have been generated in several genes involved in the GRC, and phenotypic analysis has been carried out to clarify their role in this cycle.
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Lu, Ying, Yong-Rui Wu, and Bin Han. "Anaerobic Induction of Isocitrate Lyase and Malate Synthase in Submerged Rice Seedlings Indicates the Important Metabolic Role of the Glyoxylate Cycle." Acta Biochimica et Biophysica Sinica 37, no. 6 (2005): 406–14. http://dx.doi.org/10.1111/j.1745-7270.2005.00060.x.

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Abstract The glyoxylate cycle is a modified form of the tricarboxylic acid cycle that converts C2 compounds into C4 dicarboxylic acids at plant developmental stages. By studying submerged rice seedlings, we revealed the activation of the glyoxylate cycle by identifying the increased transcripts of mRNAs of the genes of isocitrate lyase (ICL) and malate synthase (MS), two characteristic enzymes of the glyoxylate cycle. Northern blot analysis showed that ICL and MS were activated in the prolonged anaerobic environment. The activity assay of pyruvate decarboxylase and ICL in the submerged seedlin
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Dolan, Stephen K., and Martin Welch. "The Glyoxylate Shunt, 60 Years On." Annual Review of Microbiology 72, no. 1 (2018): 309–30. http://dx.doi.org/10.1146/annurev-micro-090817-062257.

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2017 marks the 60th anniversary of Krebs’ seminal paper on the glyoxylate shunt (and coincidentally, also the 80th anniversary of his discovery of the citric acid cycle). Sixty years on, we have witnessed substantial developments in our understanding of how flux is partitioned between the glyoxylate shunt and the oxidative decarboxylation steps of the citric acid cycle. The last decade has shown us that the beautifully elegant textbook mechanism that regulates carbon flux through the shunt in E. coli is an oversimplification of the situation in many other bacteria. The aim of this review is to
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Zhou, X. "The glyoxylate cycle in Candida albicans infection." Trends in Biotechnology 19, no. 9 (2001): 330. http://dx.doi.org/10.1016/s0167-7799(01)01773-5.

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Alberty, Robert A. "Thermodynamics and Kinetics of the Glyoxylate Cycle†." Biochemistry 45, no. 51 (2006): 15838–43. http://dx.doi.org/10.1021/bi061829e.

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Pistelli, L., P. Perata, and A. Alpi. "Effect of Leaf Senescence on Glyoxylate Cycle Enzyme Activities." Functional Plant Biology 19, no. 6 (1992): 723. http://dx.doi.org/10.1071/pp9920723.

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In order to elucidate the metabolism of the peroxisomes during foliar senescence of leaf beet (Beta vulgaris L., var. cicla), peroxisomal activities have been determined at various stages of senescence. Catalase and hydroxypyruvate reductase activities decreased whereas those of the β-oxidation pathway and glyoxylate cycle enzymes increased at the same time. The increased activities of malate synthase, isocitrate lyase, malate dehydrogenase and citrate synthase indicate that the glyoxylate cycle might be activated during the foliar senescence of leaf beet.
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Dissertations / Theses on the topic "Glyoxylate cycle"

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Chia, Tansy Mee Peing. "Fatty acid breakdown in developing embryos of Brassica napus (L)." Thesis, University of East Anglia, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251645.

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Denby, Katherine J. "Metabolic regulation of glyoxylate cycle gene expression in higher plants." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240527.

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Barrett, Matthieu D. "Antisense approach to understanding glyoxylate cycle function in higher plants." Thesis, University of Edinburgh, 1996. http://hdl.handle.net/1842/10742.

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The glyoxylate cycle is a key step in the conversion of storage lipids to sugars in germinating oilseeds. This conversion is thought to allow seedling growth prior to the development of photosynthetic organs. The glyoxylate cycle is thought not only to operate during this stage of development but also during senescence, starvation, pollen development and embryogenesis. It is not known how important the cycle is for plant physiology and development. Two enzymes isocitrate lyase (ICL, EC 4.1. 3.1 ) and malate synthase (MS, EC 4. 1. 3. 2), are central to the cycle. In order to elucidate the funct
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Kabran-Gnankon, Affoue Philomene. "Métabolisme lipidique et cycle du glyoxylate chez la levure Yarrowia lipolytica." Phd thesis, AgroParisTech, 2010. http://pastel.archives-ouvertes.fr/pastel-00625879.

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La levure Yarrowia lipolytica est une levure oléagineuse capable de croître sur les substrats hydrophobes et les composés en C2 comme seul source de carbonne. La première partie de notre étude a permis de déterminer la localisation des protéines Lro1p et Dga1p impliquées dans la dernière étape de la synthèse des triglycérides. Ces protéines sont localisées dans la membrane cytoplasmique et à la surface des corps lipidique pour Lro1p et à la surface des corps lipidique pour Lro1p et à la surface des corps lipidiques pour dga1p. La deuxième partie de cette étude a permis d'avoir une idée plus pr
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Gabriel, Frédéric. "Etude fonctionnelle de la β-oxydation chez la levure pathogène opportuniste Candida lusitaniae : caractérisation d’une voie mitochondriale et peroxysomale Fox2p-dépendante et mise en évidence d’une voie peroxysomale alternative Fox2p-indépendante de catabolisme des acides gras". Thesis, Bordeaux 2, 2011. http://www.theses.fr/2011BOR21896/document.

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Les levures Candida sont des pathogènes opportunistes émergents. Après phagocytose macrophagique, C. albicans reprogramme son métabolisme pour faire face à une carence carbonée et induit 2 voies métaboliques, le cycle du glyoxylate et la β-oxydation. Notre objectif est d’étudier le lien entre β-oxydation, capacité de résistance à la phagocytose et virulence dans notre modèle biologique C. lusitaniae. Chez les levures Ascomycètes la β-oxydation, essentielle pour dégrader les acides gras (AG), est présumée être exclusivement peroxysomale.Nous avons construit 3 mutants nuls chez C. lusitaniae : i
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Villela, Helena Dias Müller. "Utilização das técnicas de engenharia genética e bioquímica em Chlamydomonas reinhardtii visando o aumento da produção de lipídeos para obtenção de biocombustível." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-01102014-080611/.

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Os impactos ambientais causados pela queima dos combustíveis fósseis e pela sua manipulação, aliados ao crescente preço dos combustíveis, têm fomentado a procura de novos recursos renováveis e o desenvolvimento de novas tecnologias que suportem as necessidades desse mercado. Os biocombustíveis são recursos biodegradáveis e renováveis, que vêm se revelando uma alternativa economicamente viável. No entanto, a atual geração de biocombustíveis possui alguns pontos negativos, tais como: utilização de solos férteis e competição com a indústria de alimentos, uma vez que utiliza culturas como soja, mi
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SILVA, NETO Benedito Rodrigues da. "Malato sintase de Paracoccidioides brasiliensis é uma proteína ligada à superfície que se comporta como uma anchorless adesina." Universidade Federal de Goiás, 2009. http://repositorio.bc.ufg.br/tede/handle/tde/1295.

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Made available in DSpace on 2014-07-29T15:16:38Z (GMT). No. of bitstreams: 1 Dissert part 1 Benedito.pdf: 5001631 bytes, checksum: 7d51091e361c98586e384be80ebe9178 (MD5) Previous issue date: 2009-05-11<br>The pathogenic fungus Paracoccidioides brasiliensis causative of Paracoccidioidomycosis (PCM), a pulmonary mycose acquired by inhalation of fungal airborne propagules, which may disseminate to several organs and tissues leading to a severe form of the disease. Adhesion and invasion to host cells are essential steps involved in the internalization and dissemination of pathogens. Inside host,
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Yoon, Jeong-Jun. "Enzymatic Studies on the Glyoxylate and TCA Cycles during Fruit Body Formation of Wood-Decay Fungi." Kyoto University, 2002. http://hdl.handle.net/2433/149521.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第9840号<br>農博第1300号<br>新制||農||855(附属図書館)<br>学位論文||H14||N3727(農学部図書室)<br>UT51-2003-B380<br>京都大学大学院農学研究科応用生命科学専攻<br>(主査)教授 島田 幹夫, 教授 加藤 暢夫, 教授 江﨑 信芳<br>学位規則第4条第1項該当
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Alencar, Nara LÃdia Mendes. "MobilizaÃÃo de reservas endospÃrmicas de pinhÃo-manso durante a germinaÃÃo e desenvolvimento da plÃntula sob condiÃÃes de estresse salino." Universidade Federal do CearÃ, 2014. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11759.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>O pinhÃo-manso (Jatropha curcas L.) à uma planta oleaginosa, pertencente à famÃlia Euphorbiaceae, cujas sementes sÃo reconhecidas como matÃria-prima com potencial para a produÃÃo de Ãleo. Essa planta tambÃm à considerada tolerante a condiÃÃes adversas, tais como dÃficit hÃdrico e deficiÃncia nutricional do solo, o que favorece o seu cultivo em regiÃes Ãridas e semiÃridas. Objetivou-se avaliar os efeitos do estresse salino sobre a germinaÃÃo e a mobilizaÃÃo das reservas de sementes e plÃntulas de pinhÃo-manso, por meio de anÃlises
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Wan-LinWu and 吳宛霖. "Study of glyoxylate cycle regulation by sucrose during protocorm growth in Phalaenopsis aphrodite." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/t489pe.

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碩士<br>國立成功大學<br>熱帶植物科學研究所<br>102<br>The glyoxylate cycle plays a central role in converting storage oil to soluble carbohydrate in oilseeds to support growth during germination. Enzyme activity or transcript accumulation of key enzymes of the glyoxylate cycle, isocitrate lyase (ICL)/ malate synthase (MLS), are downregulated by carbon catabolite repression during seed germination. Without endosperm and cotyledon, orchid seeds was found large amount of lipid reserved in the immature embryo, and carbohydrates play a vital role to support protocorm development during tissue culture. To investigate
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Books on the topic "Glyoxylate cycle"

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Bédard, Sylvain. Le cycle du glyoxylate dans la détoxicaton de l'aluminium par Pseudomonas fluorescens. Université Laurentienne, 1999.

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Agy, Michael Bruce. Studies of Coccidioides immitis: The glyoxylate cycle and the organization of the ribosomal genes. 1986.

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Book chapters on the topic "Glyoxylate cycle"

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Cornah, Johanna E., and Steven M. Smith. "Synthesis and Function of Glyoxylate Cycle Enzymes." In Plant Peroxisomes. Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-015-9858-3_3.

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Cohen, G. N. "The Tricarboxylic Acid Cycle and the Glyoxylate Bypass." In Microbial Biochemistry. Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-8908-0_8.

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Cohen, Georges N. "The tricarboxylic acid cycle and the glyoxylate bypass." In Microbial Biochemistry. Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2237-1_8.

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Bott, Michael, and Bernhard J. Eikmanns. "TCA Cycle and Glyoxylate Shunt of Corynebacterium glutamicum." In Corynebacterium glutamicum. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-29857-8_10.

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Cohen, Georges N. "The Tricarboxylic Acid Cycle and the Glyoxylate Bypass." In Microbial Biochemistry. Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-017-7579-3_8.

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Cohen, G. N. "The Tricarboxylic Acid Cycle and the Glyoxylate Bypass." In Microbial Biochemistry. Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-9437-7_8.

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Beeckmans, S., and J. P. Xie. "Glyoxylate Cycle☆." In Reference Module in Biomedical Sciences. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-801238-3.02440-5.

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Beeckmans, S. "Glyoxylate Cycle." In Encyclopedia of Microbiology. Elsevier, 2009. http://dx.doi.org/10.1016/b978-012373944-5.00075-4.

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"Glyoxylate Cycle." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_7018.

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Conference papers on the topic "Glyoxylate cycle"

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Li, Ya-Qing, and Yu-Xiang Liu. "Relationship between Glyoxylate Cycle and Nitrification Efficiency based on Heterotrophic Nitrification Bacterium Acinetobacter sp.Y1." In 2nd 2016 International Conference on Sustainable Development (ICSD 2016). Atlantis Press, 2017. http://dx.doi.org/10.2991/icsd-16.2017.34.

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Reports on the topic "Glyoxylate cycle"

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McFadden, B. A. [Isocitrate lyase and glyoxylate cycle]. Progress report, May 1, 1990--May 1, 1993. Office of Scientific and Technical Information (OSTI), 1993. http://dx.doi.org/10.2172/10142137.

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McFadden, B. A. Isocitrate lyase and the glyoxylate cycle. Progress report, February 15, 1989--February 15, 1990. Office of Scientific and Technical Information (OSTI), 1990. http://dx.doi.org/10.2172/10142147.

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McFadden, B. A. Isocitrate lyase and the glyoxylate cycle. Progress report, July 1, 1988--February 15, 1989. Office of Scientific and Technical Information (OSTI), 1989. http://dx.doi.org/10.2172/10142149.

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McFadden, B. A. Isocitrate lyase and the glyoxylate cycle. Progress report, February 16, 1992--February 15, 1993. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/10142140.

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