Academic literature on the topic 'GMDP'

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Journal articles on the topic "GMDP"

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Antsiferova, Yuliya, Nataliya Sotnikova, and Elena Parfenyuk. "Different Effects of the Immunomodulatory Drug GMDP Immobilized onto Aminopropyl Modified and Unmodified Mesoporous Silica Nanoparticles upon Peritoneal Macrophages of Women with Endometriosis." BioMed Research International 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/924362.

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The aim of the present work was to compare in vitro the possibility of application of unmodified silica nanoparticles (UMNPs) and modified by aminopropyl groups silica nanoparticles (AMNPs) for topical delivery of immunomodulatory drug GMDP to the peritoneal macrophages of women with endometriosis. The absence of cytotoxic effect and high cellular uptake was demonstrated for both types of silica nanoparticles. The immobilization of GMDP on the UMNPs led to the suppression of the stimulatory effect of GMDP on the membrane expression of scavenger receptors SR-AI and SR-B, mRNAs expression of NOD
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Kuznetsova, E. G., O. M. Kuryleva, L. A. Salomatina, S. V. Kursakov, S. V. Guryanova, and V. I. Sevastyanov. "Influence of microemulsion components on transdermal delivery of immunomodulator glucosaminylmuramyl dipeptide." Russian Journal of Transplantology and Artificial Organs 22, no. 3 (2020): 149–55. http://dx.doi.org/10.15825/1995-1191-2020-3-149-155.

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This paper demonstrates a chemical way of enhancing transdermal delivery using immunomodulator glucosaminylmuramyl dipeptide (GMDP) as an example. Objective: to study in vitro the effect of various components of the microemulsion composition on GMDP diffusion through the skin from a transdermal therapeutic system (TTS). Materials and methods. Medicinal substance – glucosaminylmuramyl dipeptide (Peptek, Russia). Excipients and raw materials: sodium chloride, purified water, sodium dodecyl sulfate, docusate sodium, oak bark, apricot kernel oil, alpha-tocopheryl acetate and Decaglyn PR-20 emulsif
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Makatsariya, A. D., V. O. Bitsadze, J. Kh Khizroeva, G. Kh Vikulov, M. A. Gomberg, and A. A. Khryanin. "Efficacy and safety of glucosaminylmuramyl dipeptide in treatment of human papillomavirus-associated diseases: a systematic review." Obstetrics, Gynecology and Reproduction 13, no. 2 (2019): 132–54. http://dx.doi.org/10.17749/2313-7347.2019.13.2.132-154.

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Introduction. Human papillomavirus infection (HPV-infection) remains one of the most important health problems as it significantly reduces the quality of life and stigmatizes the patients. Also, the prevalence of cervical cancer – the most severe outcome of the HPV-infection is 5 % of the global burden of cancer. Although vaccination against human papillomavirus has been proved efficient, its availability in Russia continues to be limited. Therefore, it is important to review other methods of HPV-infection control. A number of studies have confirmed the efficacy of glucosaminylmuramyl dipeptid
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Guryanova, Svetlana V., Olga B. Gigani, Georgii O. Gudima, Anastasiya M. Kataeva, and Natalya V. Kolesnikova. "Dual Effect of Low-Molecular-Weight Bioregulators of Bacterial Origin in Experimental Model of Asthma." Life 12, no. 2 (2022): 192. http://dx.doi.org/10.3390/life12020192.

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Asthma is one of the most common noncommunicable diseases, affecting over 200 million people. A large number of drugs control asthma attacks, but there is no effective therapy. Identification of reasons for asthma and preventing this disease is a relevant task. The influence of bacterial components is necessary for the normal development of the immune system and the formation of an adequate immune response to antigens. In the absence of microorganisms or their insufficient exposure, the prerequisites are formed for excessive reactivity to harmless antigens. In the present study, we analyzed ce
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Prodeus, A. P., G. N. Gildeeva, D. R. Mamilyaeva, and I. G. Kozlov. "GLUCOSAMINYLMURAMYLDIPEPTIDE: REVIEW OF USE AND EFFECTIVENESS EVALUATION IN PEDIATRIC PRACTICE." Pediatria. Journal named after G.N. Speransky 100, no. 2 (2021): 157–66. http://dx.doi.org/10.24110/0031-403x-2021-100-2-157-166.

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A review of the accumulated data on the use of glucosaminylmuramyldipeptide (GMDP, Likopid drug) and the assessment of its effectiveness in children are presented. Objective of the research: to systematize the results of clinical trials of the efficacy and safety of GMDP therapy in neonatology and pediatrics. Materials and methods. Publications were searched for in Pubmed/MEDLINE, ScienceDirect, Cochrane, Elibrary.ru, registers of clinical trials and in open sources on the Internet. The authors assessed the level of evidence for reliability and the methodological quality of the studies. Result
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Laman, Alexander G., Richard Lathe, Anna O. Shepelyakovskaya, et al. "Muramyl peptides activate innate immunity conjointly via YB1 and NOD2." Innate Immunity 22, no. 8 (2016): 666–73. http://dx.doi.org/10.1177/1753425916668982.

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Bacterial cell wall muramyl dipeptide (MDP) and glucosaminyl-MDP (GMDP) are potent activators of innate immunity. Two receptor targets, NOD2 and YB1, have been reported; we investigated potential overlap of NOD2 and YB1 pathways. Separate knockdown of NOD2 and YB1 demonstrates that both contribute to GMDP induction of NF-κB expression, a marker of innate immunity, although excess YB1 led to induction in the absence of NOD2. YB1 and NOD2 co-migrated on sucrose gradient centrifugation, and GMDP addition led to the formation of higher molecular mass complexes containing both YB1 and NOD2. Co-immu
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Gudyrev, Oleg, Tatyana Andronova, and Evgeniya Nesterova. "The results of the study of the carcinogenic properties of glucosaminylmuramyldipeptide GMDP in chronic experiments in mice and rats." Research Results in Pharmacology 4, no. 4 (2018): 97–106. http://dx.doi.org/10.3897/rrpharmacology.4.32191.

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Introduction: The drug Licopid® (GMDP, glucosaminylmuramyldipeptide) is intended for complex therapy of conditions accompanied by secondary immunodeficiencies. This drug belongs to the group of microbial immunomodulators of bacterial origin. The transparent mechanism of action of the active substance GMDP allows putting the drug Licopid® into the category of promising immunotherapy drugs that are in demand in the complex therapy of many diseases resistant to traditional treatment. The objective of this study was to investigate the carcinogenicity of GMDP (Licopid®) in chronic animal experiment
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Gudyrev, Oleg S., Tatyana M. Andronova, and Evgeniya I. Nesterova. "The results of the study of the carcinogenic properties of glucosaminylmuramyldipeptide GMDP in chronic experiments in mice and rats." Research Results in Pharmacology 4, no. (4) (2018): 97–106. https://doi.org/10.3897/rrpharmacology.4.32191.

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Introduction: The drug Licopid® (GMDP, glucosaminylmuramyldipeptide) is intended for complex therapy of conditions accompanied by secondary immunodeficiencies. This drug belongs to the group of microbial immunomodulators of bacterial origin. The transparent mechanism of action of the active substance GMDP allows putting the drug Licopid® into the category of promising immunotherapy drugs that are in demand in the complex therapy of many diseases resistant to traditional treatment. The objective of this study was to investigate the carcinogenicity of GMDP (Licopid®) in chronic animal experiment
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Nemtsova, E. R., O. A. Bezborodova, N. B. Morozova, et al. "Efficacy of combined treatment of experimental tumors with cytostatic agents and GMDP-A." Russian Journal of Biotherapy 16, no. 2 (2017): 13–22. http://dx.doi.org/10.17650/1726-9784-2017-16-2-13-22.

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Objective of the study. To evaluate the pharmacological effects of N-acetylglucosaminyl-N-acetylmuramyl-L-alanyl-D-glutamic acid (GMDP-A) as a modifier of biological reactions, i. e. to study its modifying action in regard to traditional cytostatic chemotherapy. Materials and methods. The used drug agents were GMDP-A, cisplatinum, gemcitabine, cyclophosphamide, 5-fluorouracil. The transplanted murine tumors were Р-388 lymphocytic leukemia and S-37 sarcoma (solid and ascites variants), B-16 melanoma, CC-5 squamous cell carcinoma of the cervix uteri, C-26 adenocarcinoma of the colon, and AKATOL
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Guryanova, Svetlana V., and Anastasiya Kataeva. "Inflammation Regulation by Bacterial Molecular Patterns." Biomedicines 11, no. 1 (2023): 183. http://dx.doi.org/10.3390/biomedicines11010183.

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Stimulation of innate immunity by bacterial molecular patterns can induce an enhanced cellular immune response to pathogens that are associated with innate immune memory shaped by epigenetic changes. Immunological memory can be expressed in the acceleration/ intensification of inflammation, as well as in the exact opposite—to maintain tolerance and non-response to a repeated stimulus. Tolerance is one of the central concepts of immunity and is ensured by the consistency of all parts of the immune response. The severe consequences of inflammation force researchers to study in detail all stages
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Dissertations / Theses on the topic "GMDP"

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Al, Sabban Wesam H. "Autonomous vehicle path planning for persistence monitoring under uncertainty using Gaussian based Markov decision process." Thesis, Queensland University of Technology, 2015. https://eprints.qut.edu.au/82297/1/Wesam%20H_Al%20Sabban_Thesis.pdf.

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One of the main challenges facing online and offline path planners is the uncertainty in the magnitude and direction of the environmental energy because it is dynamic, changeable with time, and hard to forecast. This thesis develops an artificial intelligence for a mobile robot to learn from historical or forecasted data of environmental energy available in the area of interest which will help for a persistence monitoring under uncertainty using the developed algorithm.
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Egerer, Johannes. "The Golgin GMAP-210." Diss., lmu, 2008. http://nbn-resolving.de/urn:nbn:de:bvb:19-88207.

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Beneš, Vratislav. "Ekonomické modely realizované neuronovou sítí typu GMDH." Master's thesis, Vysoká škola ekonomická v Praze, 2007. http://www.nusl.cz/ntk/nusl-7680.

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This diploma thesis is about design and realization of neural network MIA GMDH for ekonomical modelling by inductive method. Models are compared with statistical methods by quallity and usebility degree. An application was developed for verification of functionality on experiments. The same experiments were run in econometrical software. The results were compared. The MIA GMDH is suitable for economic modelling.
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Soares, Wendell Silva. "Aplicabilidade e desempenho do global média transmission protocol (GMTP)." Universidade Federal de Alagoas, 2016. http://www.repositorio.ufal.br/handle/riufal/1612.

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This work presents a study about the implementation of the Global Media Transmission Protocol (GMTP) in the Linux operating system. Currently, Internet live streaming applications require various middlewares incompatible among them, as they have different network services requirements. As a consequence, two end-systems using distinct applications can not cooperate to share a given data flow from a streaming server, increasing network resource consumption. For that reason, the GMTP was proposed as a network protocol that decouples the functions used for rendering the media flow to the user from th
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Mantler, Mathias. "Der GMP-Vertrag aus bauvergaberechtlicher Sicht /." Frankfurt ; New York : Lang, 2004. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=010635104&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Dissertation Koln, Universität, 2003. Zugl.: Köln, Universiẗat, Diss., 2003 u. d. T.: Der GMP-Vertrag als neue Vertrags- und Wettbewerbsform aus bauvergaberechtlicher Sicht.<br>Includes bibliographical references (p. 187-204).
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Lu, Shu. "Power transformer magnetization under GIC/GMD." Diss., This resource online, 1994. http://scholar.lib.vt.edu/theses/available/etd-09232008-144706/.

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Tang, Katherine Mary. "Targets of cyclic GMP in blood platelets, photolabelling, mutagenesis and pharmacological analysis of the cyclic GMP-inhibited phosphodiesterase." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0016/NQ30173.pdf.

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Gao, Jin. "A Dynamic Analysis of Variable Annuities and Guarenteed Minimum Benefits." Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/rmi_diss/26.

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We determine the optimal allocation of funds between the fixed and variable sub-accounts in a variable annuity with a GMDB (Guaranteed Minimum Death Benefit) clause featuring partial withdrawals by using a utility-based approach. In section two, the Merton method is applied by assuming that individuals allocate funds optimally in order to maximize the expected utility of lifetime consumption. It also reflects bequest motives by including the recipient's utility in terms of the policyholder's guaranteed death benefits. We derive the optimal transfer choice by the insured, and furthermore price
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Almakhlafi, Ahmad. "The generator maintenance scheduling problem : benchmarks, local search and metaheuristics." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/the-generator-maintenance-scheduling-problembenchmarks-local-search-and-metaheuristics(b36d7f0f-93f7-4388-8ad9-4e84ae8fc245).html.

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Scheduling problems are common in a wide range of real-world industries and strategies for tackling them can impact on profits significantly. The careful planning and precise timing of industrial events and processes can maximize the utilization of resources, improve efficiency and reduce costs. One important type of scheduling problem from the domain of maintenance planning is the Generator Maintenance Scheduling Problem (GMSP) in the power industry. This thesis makes three broad contributions. First, we introduce a set of 23 real-world instances of the problem of different characteristics an
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Engelhardt, Thomas. "The regulation of cyclic GMP during anaesthesia." Thesis, University of Aberdeen, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409272.

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The glutamate-NO-cyclic GMP pathway has previously been identified as a potential major target for general anaesthetic agents. An animal model of type I NOS gene disrupted mice was employed to investigate <i>in vivo </i>effects of the general anaesthetic agents isoflurane, ketamine, pentobarbital, and propofol on cyclic GMP in the presence or absence of the isoform specific NOS inhibitor, 7-nitroindazole. G protein function was studied <i>ex vivo </i>in whole brains. Primary neuronal cell cultures were employed to investigate the effects of anaesthetic agents on glutamate stimulated cyclic GMP
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Books on the topic "GMDP"

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Parfenyuk, E. V. Silica nanoparticles as drug delivery system for immunomodulator GMDP. ASME, 2012.

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Vogel, Patric U. B. GMP-Risikoanalysen. Springer Fachmedien Wiesbaden, 2021. http://dx.doi.org/10.1007/978-3-658-35208-0.

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Sauer, Karin, ed. c-di-GMP Signaling. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7240-1.

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Vogel, Patric U. B., Jennifer Borrelli, and Claudia Dochow. Funktionsträger im GMP-Umfeld. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-68720-8.

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Muzeum Górnośląskie w Bytomiu. Galeria Malarstwa Polskiego. GMP: Galeria Malarstwa Polskiego. Muzeum Górnośląskie, 2017.

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Commission, Gujarat Ecology, Gujarat Ecological Society, and Gujarat Mineral Development Corporation, eds. Ecological restoration of mining sites of GMDC. Gujarat Ecological Commission, 1997.

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Krieg, Thomas, and Robert Lukowski, eds. Guanylate Cyclase and Cyclic GMP. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-459-3.

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Durivage, Mark Allen. Certified pharmaceutical GMP professional handbook. ASQ Quality Press, 2014.

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Wolfe, Alan J., and Karen L. Visick, eds. The Second Messenger Cyclic Di-GMP. ASM Press, 2010. http://dx.doi.org/10.1128/9781555816667.

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Kim, Myung-Soo, and Kenji Shimada, eds. Geometric Modeling and Processing - GMP 2006. Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/11802914.

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Book chapters on the topic "GMDP"

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Beitzel, Steven M., Eric C. Jensen, and Ophir Frieder. "GMAP." In Encyclopedia of Database Systems. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4899-7993-3_493-2.

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Beitzel, Steven M., Eric C. Jensen, and Ophir Frieder. "GMAP." In Encyclopedia of Database Systems. Springer US, 2009. http://dx.doi.org/10.1007/978-0-387-39940-9_493.

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Beitzel, Steven M., Eric C. Jensen, and Ophir Frieder. "GMAP." In Encyclopedia of Database Systems. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4614-8265-9_493.

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Neels, Oliver. "GMP." In Handbook of Nuclear Medicine and Molecular Imaging for Physicists. CRC Press, 2022. http://dx.doi.org/10.1201/9780429489501-8.

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Bährle-Rapp, Marina. "GMP." In Springer Lexikon Kosmetik und Körperpflege. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_4457.

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Ledvina, M., and J. Jezek. "An alternative synthesis of O-(2-acylamino-2-deoxy-β-D-glucopyranosyl)-(1->4)-N-acetylnormuramoyl-L-α- aminobutanoyl-D-isoglutamines, analogs of GMDP with immunopotentiative activity." In Peptides 1994. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-1468-4_337.

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Oeser, W. "GMP-Richtlinien." In Taschenbuch für Lebensmittelchemiker und -technologen. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-58220-2_1.

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Nikolaevskaya, Elena A., Alexandr N. Khimich, and Tamara V. Chistyakova. "About GMP." In Programming with Multiple Precision. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-25673-8_2.

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Bredenfeld, Ansgar, Thomas Christaller, Horst Guenther, et al. "GMD-Robots." In RoboCup 2000: Robot Soccer World Cup IV. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/3-540-45324-5_91.

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Schomburg, D., M. Salzmann, and D. Stephan. "GMP reductase." In Enzyme Handbook 7. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78521-4_67.

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Conference papers on the topic "GMDP"

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Jiang, Wanchang, and Zhenxiao Sun. "A DAS Signal Events Recognition Method Based on 1DCNNs-gMLP." In 2024 International Joint Conference on Neural Networks (IJCNN). IEEE, 2024. http://dx.doi.org/10.1109/ijcnn60899.2024.10651117.

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Sato, Koki, Ryo Kobayashi, Sho Yamauchi, and Keiji Suzuki. "Time Scale Analysis of Long Sequential Robot Behavior Generated by gMLP." In 2024 16th IIAI International Congress on Advanced Applied Informatics (IIAI-AAI). IEEE, 2024. http://dx.doi.org/10.1109/iiai-aai63651.2024.00079.

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Babin, Artem S., Mikhail I. Baryshnikov, and Yuriy E. Gapanyuk. "Group Method of Data Handling (GMDH) in Forecasting Electric Power Consumption." In 2025 7th International Youth Conference on Radio Electronics, Electrical and Power Engineering (REEPE). IEEE, 2025. https://doi.org/10.1109/reepe63962.2025.10971009.

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Lhazmir, Safae, Omar Ait Oualhaj, Abdellatif Kobbane, El Mehdi Amhoud, and Jalel Ben-Othman. "UAV for Wireless Power Transfer in IoT Networks: A GMDP approach." In ICC 2020 - 2020 IEEE International Conference on Communications (ICC). IEEE, 2020. http://dx.doi.org/10.1109/icc40277.2020.9148956.

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Shengtun Li, Yiwei Chen, and E. L. Leiss. "GMDP: a novel unified neuron model for multilayer feedforward neural networks." In Proceedings of 1994 IEEE International Conference on Neural Networks (ICNN'94). IEEE, 1994. http://dx.doi.org/10.1109/icnn.1994.374147.

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Arteaga, R., F. Tobajas, R. Esper-Chain, V. de Armas, and Roberto Sarmiento. "GMDS." In the conference. ACM Press, 2008. http://dx.doi.org/10.1145/1403375.1403725.

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Robertson, Stephen. "On GMAP." In the 15th ACM international conference. ACM Press, 2006. http://dx.doi.org/10.1145/1183614.1183630.

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Liu, Shuaihu, and Heshan Wang. "SFM-GMDH: Sparse Feature Mapping GMDH Network for Time Series Prediction." In 2024 39th Youth Academic Annual Conference of Chinese Association of Automation (YAC). IEEE, 2024. http://dx.doi.org/10.1109/yac63405.2024.10598553.

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Soares, Wendell, Mário André Costa, Joilnen Leite, Leandro De Sales, and André Freitas. "Aplicabilidade do Global Media Transmission Protocol (GMTP)." In Workshop Pré-IETF. Sociedade Brasileira de Computação - SBC, 2015. http://dx.doi.org/10.5753/wpietf.2015.10468.

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Os sistemas para transmiss˜ao de mídias ao vivo na Internet atuais dependem de vários middlewares, pois eles precisam de servic¸os de rede específicos. Isso favorece o aumento do consumo de recursos de rede e dificulta a implementação de sistemas de streaming ao vivo que possam cooperar entre si. O Global Media Transmission Protocol (GMTP) aborda este problema, propondo um protocolo de distribuição de mídias ao vivo pela Internet. No GMTP, utilizam-se algoritmos P2P a nível de socket, a fim de construir uma rede de favores constituída entre roteadores. A rede de favores é gerenciada pelos serv
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Sezer, Nurettin, Irfan Batur, and Ibrahim Arı. "Green Mobility Application (GMAP)." In Qatar Foundation Annual Research Conference Proceedings. Hamad bin Khalifa University Press (HBKU Press), 2016. http://dx.doi.org/10.5339/qfarc.2016.eesp3063.

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Reports on the topic "GMDP"

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Disa, R., C. Van Wie, K. Arnold, J. Altemueller, and A. Whelan. Geometric Modeling Applications Interface Programs (GMAP). GMAP/PDDI system Component Product Specification (as Built). Volume 1. Defense Technical Information Center, 1990. http://dx.doi.org/10.21236/ada228114.

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Mate, Adam. The Carrington GMD project. Office of Scientific and Technical Information (OSTI), 2019. http://dx.doi.org/10.2172/1571580.

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Disa, R., C. Van Wie, K. Arnold, J. Altemueller, and A. Whelan. Geometric Modeling Applications Interface Programs (GMAP). GMAP/PDDI system Component Product Specification (as Built). Volume 2. Schema Manager Listing. Defense Technical Information Center, 1990. http://dx.doi.org/10.21236/ada228115.

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Shiihi, Solomon, U. G. Okafor, Zita Ekeocha, Stephen Robert Byrn, and Kari L. Clase. Improving the Outcome of GMP Inspections by Improving Proficiency of Inspectors through Consistent GMP Trainings. Purdue University, 2021. http://dx.doi.org/10.5703/1288284317433.

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Approximately 90% of the pharmaceutical inspectors in a pharmacy practice regulatory agency in West Africa have not updated their training on Good Manufacturing Practice (GMP) inspection in at least eight years. However, in the last two years the inspectors relied on learning-on-the job skills. During this time, the agency introduced about 17% of its inspectors to hands-on GMP trainings. GMP is the part of quality assurance that ensures the production or manufacture of medicinal products is consistent in order to control the quality standards appropriate for their intended use as required by t
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Woodroffe, Jesse R., and Lisa Marie Winter. Update on LANL GMD Research Tasks. Office of Scientific and Technical Information (OSTI), 2018. http://dx.doi.org/10.2172/1469512.

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Johnson, Eric E. ARGOS: A Research GMMP Operating System: Overview and Interfaces. Defense Technical Information Center, 1989. http://dx.doi.org/10.21236/ada213871.

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Phillips, L., K. Perlotto, D. K. Emmerson, P. Blasko, and D. Jacobs. Geometric Modeling Applications Interface Program (GMAP). Volume 1. Executive Overview. Defense Technical Information Center, 1989. http://dx.doi.org/10.21236/ada237280.

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Phillips, L., K. Perlotto, D. K. Emmerson, P. Blasko, and D. Jacobs. Geometric Modeling Applications Interface Program (GMAP). Volume 2. Program Description. Defense Technical Information Center, 1989. http://dx.doi.org/10.21236/ada237281.

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Rivera, Michael Kelly, and Russell Whitford Bent. GMD Coupling to Power Systems and Disturbance Mitigation. Office of Scientific and Technical Information (OSTI), 2018. http://dx.doi.org/10.2172/1418747.

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Lubowa, Nasser, Zita Ekeocha, Stephen Robert Byrn, and Kari L. Clase. Pharmaceutical Industry in Uganda: A Review of the Common GMP Non-conformances during Regulatory Inspections. Purdue University, 2021. http://dx.doi.org/10.5703/1288284317442.

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Abstract:
The prevalence of substandard medicines in Africa is high but not well documented. Low and Middle-Income Countries (LMICs) are likely to face considerable challenges with substandard medications. Africa faces inadequate drug regulatory practices, and in general, compliance with Good Manufacturing Practices (GMP) in most of the pharmaceutical industries is lacking. The majority of pharmaceutical manufacturers in developing countries are often overwhelmed by the GMP requirements and therefore are unable to operate in line with internationally acceptable standards. Non-conformances observed durin
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