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1

Jubinsky, PT, DG Nathan, DJ Wilson, and CA Sieff. "A low-affinity human granulocyte-macrophage colony-stimulating factor/murine erythropoietin hybrid receptor functions in murine cell lines." Blood 81, no. 3 (1993): 587–91. http://dx.doi.org/10.1182/blood.v81.3.587.587.

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Abstract To identify domains in hematopoietic growth factor receptors that are important for signal transduction, a hybrid receptor (GMER) was constructed by splicing the DNA of the entire extracellular and transmembrane domains of the human granulocyte-macrophage colony- stimulating factor (GM-CSF) receptor alpha 2 subunit (GMR) to the cytoplasmic domain of the murine erythropoietin receptor (mEpoR). The hybrid receptor was introduced into the interleukin-3 factor-dependent murine hematopoietic cell line Ba/F3. Cells that expressed high receptor numbers were selected by cell sorting using phy
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2

Jubinsky, PT, DG Nathan, DJ Wilson, and CA Sieff. "A low-affinity human granulocyte-macrophage colony-stimulating factor/murine erythropoietin hybrid receptor functions in murine cell lines." Blood 81, no. 3 (1993): 587–91. http://dx.doi.org/10.1182/blood.v81.3.587.bloodjournal813587.

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To identify domains in hematopoietic growth factor receptors that are important for signal transduction, a hybrid receptor (GMER) was constructed by splicing the DNA of the entire extracellular and transmembrane domains of the human granulocyte-macrophage colony- stimulating factor (GM-CSF) receptor alpha 2 subunit (GMR) to the cytoplasmic domain of the murine erythropoietin receptor (mEpoR). The hybrid receptor was introduced into the interleukin-3 factor-dependent murine hematopoietic cell line Ba/F3. Cells that expressed high receptor numbers were selected by cell sorting using phycoerythri
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3

Mutalik, Anirudh V., Rashmi Ramanathan, Seetharaman Narayanan, et al. "Evaluating the effectiveness of curriculum implementation and supplementation program in a private medical college in south India." International Journal Of Community Medicine And Public Health 9, no. 10 (2022): 3753. http://dx.doi.org/10.18203/2394-6040.ijcmph20222567.

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Background: The new competency based medical curriculum was introduced in India from 2019. The curriculum implementation support program (CISP) developed by medical council of India, provides the much-needed intellectual support to colleges for smooth transition from existing to the new curriculum. This study was done to assess the effectiveness of CISP program by comparing the pretest and posttest questionnaire.Methods: This retrospective cross-sectional study was conducted among 30 medical teachers in a medical college after getting Institutional Ethical committee clearance. During the CISP
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Ayukawa, Tomonori, Kenjiroo Matsumoto, Hiroyuki O. Ishikawa, et al. "Rescue of Notch signaling in cells incapable of GDP-l-fucose synthesis by gap junction transfer of GDP-l-fucose in Drosophila." Proceedings of the National Academy of Sciences 109, no. 38 (2012): 15318–23. http://dx.doi.org/10.1073/pnas.1202369109.

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Notch (N) is a transmembrane receptor that mediates cell–cell interactions to determine many cell-fate decisions. N contains EGF-like repeats, many of which have an O-fucose glycan modification that regulates N-ligand binding. This modification requires GDP-l-fucose as a donor of fucose. The GDP-l-fucose biosynthetic pathways are well understood, including the de novo pathway, which depends on GDP-mannose 4,6 dehydratase (Gmd) and GDP-4-keto-6-deoxy-d-mannose 3,5-epimerase/4-reductase (Gmer). However, the potential for intercellularly supplied GDP-l-fucose and the molecular basis of such trans
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Nirmalya, Saha, Kumar Poddar Jayanta, and Tripura Kaushik. "Impact of CISP II training in CBME Curriculum at Tripura Medical College." International Journal of Pharmaceutical and Clinical Research 15, no. 4 (2023): 1384–91. https://doi.org/10.5281/zenodo.12680564.

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<strong>Background:&nbsp;</strong>Medical teachers trained in conventional education system were in need to go through new faculty development programme, Curriculum Implementation Support Programme (CISP), for effective implementation and functioning of Competency Based Medical Education (CBME) curriculum. The medical teachers trained with CISP were shown with much better perceptions of CBME Curriculum Implementation comparing to those of the medical teachers who were yet to be trained. For this a well organised educational process for faculty development programme was mandatory. At the same t
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Schwarz, M. Roy, Andrzej Wojtczak, and David Stern. "The outcomes of global minimum essential requirements (GMER) pilot implementation in China." Medical Teacher 29, no. 7 (2007): 699–705. http://dx.doi.org/10.1080/01421590701749821.

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7

Pless, Miklos, Koenraad Norga, Martin Carroll, Markus H. Heim, Alan D. D'Andrea, and Bernard Mathey-Prevot. "Receptors That Induce Erythroid Differentiation of Ba/F3 Cells: Structural Requirements and Effect on STAT5 Binding." Blood 89, no. 9 (1997): 3175–85. http://dx.doi.org/10.1182/blood.v89.9.3175.

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Abstract Ectopic expression of the erythropoietin receptor (EpoR) in the interleukin-3 (IL-3)–dependent cell line Ba/F3 results in growth and partial erythroid differentiation in Epo. In contrast, introduction and activation of the interleukin-5 receptor (IL-5R) or of the granulocyte-macrophage colony-stimulating factor receptor (GM-CSFR) results in proliferation only. As this effect is specific to the EpoR, the role of its extracellular or cytoplasmic domain in differentiation was tested after construction of two chimeric receptors. One receptor contained the extracellular domain of EpoR fuse
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8

Goyal, Parmod Kumar, and Monika Gupta. "Differences between Graduate Medical Education Regulations 1997 (GMER 1997) and Graduate Medical Education Regulations 2019 (GMER 2019) in respect to teaching and assessment of subject of Forensic Medicine and Toxicology." Journal of Punjab Academy of Forensic Medicine & Toxicology 21, no. 1 (2021): 258–62. http://dx.doi.org/10.5958/0974-083x.2021.00049.2.

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9

Goyal, Parmod Kumar, and Monika Gupta. "Differences between Graduate Medical Education Regulations 1997 (GMER 1997) and Graduate Medical Education Regulations 2019 (GMER 2019) in respect to teaching and assessment of subject of Forensic Medicine and Toxicology." Journal of Punjab Academy of Forensic Medicine & Toxicology 21, no. 1 (2021): 258–62. http://dx.doi.org/10.5958/0974-083x.2021.00049.2.

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10

Shangguan, Wei, YongJiu Dai, Carlos García-Gutiérrez, and Hua Yuan. "Particle-Size Distribution Models for the Conversion of Chinese Data to FAO/USDA System." Scientific World Journal 2014 (2014): 1–11. http://dx.doi.org/10.1155/2014/109310.

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We investigated eleven particle-size distribution (PSD) models to determine the appropriate models for describing the PSDs of 16349 Chinese soil samples. These data are based on three soil texture classification schemes, including one ISSS (International Society of Soil Science) scheme with four data points and two Katschinski’s schemes with five and six data points, respectively. The adjusted coefficient of determinationr2, Akaike’s information criterion (AIC), and geometric mean error ratio (GMER) were used to evaluate the model performance. The soil data were converted to the USDA (United S
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Ghanbarian-Alavijeh, B., and A. M. Liaghat. "Evaluation of soil texture data for estimating soil water retention curve." Canadian Journal of Soil Science 89, no. 4 (2009): 461–71. http://dx.doi.org/10.4141/cjss08066.

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The soil water retention curve (SWRC) is one of the basic characteristics used in determining soil hydraulic properties, including unsaturated hydraulic conductivity. As its measurement is time consuming and difficult, much effort has been expended to develop indirect methods, such as pedotransfer functions and empirical relationships, to estimate SWRC. In this study, three methods were evaluated based on estimation of retention models parameters and, consequently, the soil water retention curve. For this purpose, soil data collected from three data bases, totaling 72 soil samples with 11 diff
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Parviz, Laleh. "Assessing accuracy of barley yield forecasting with integration of climate variables and support vector regression." Annales Universitatis Mariae Curie-Sklodowska, sectio C – Biologia 73, no. 1 (2019): 19. http://dx.doi.org/10.17951/c.2018.73.1.19-30.

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&lt;p&gt;Investigations of the relation between crop yield and climate variables are crucial for agricultural studies and decision making related to crop monitoring. Multiple linear regression (MLR) and support vector regression (SVR) are used to identify and model the impact of climate variables on barley yield. The climate variables of 36 years (1982–2017) are gathered from three provinces of Iran with different climate: Yazd (arid), Zanjan (semi-arid), Gilan (very humid). Air temperature by high correlation coefficient with barley yield was introduced as the dominant climate variable. Accor
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13

Xiao, Haipeng, Liqing Xian, Xueqing Yu, and Jianping Wang. "Medical curriculum reform in Sun Yat-sen University: implications from the results of GMER evaluation in China." Medical Teacher 29, no. 7 (2007): 706–10. http://dx.doi.org/10.1080/01421590701713579.

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14

Järvinen, Nina, Minna Mäki, Jarkko Räbinä, Christophe Roos, Pirkko Mattila, and Risto Renkonen. "Cloning and expression of Helicobacter pylori GDP-l -fucose synthesizing enzymes (GMD and GMER) in Saccharomyces cerevisiae." European Journal of Biochemistry 268, no. 24 (2001): 6458–64. http://dx.doi.org/10.1046/j.0014-2956.2001.02601.x.

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15

Mady, Ahmed Yehia, and Evgeny Shein. "Estimating Soil Thermal Diffusivity Using Pedotransfer Functions with Nonlinear Regression." Open Agriculture Journal 12, no. 1 (2018): 164–73. http://dx.doi.org/10.2174/1874331501812010164.

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Background and Objective:Pedotransfer Functions (PTFs) are widely used for estimating soil thermal diffusivity. Some attempts have been made to indirectly predict soil thermal diffusivity from the easy available fundamental soil physics properties. The aim of the work was to validate usage PTFs with Nonlinear Regression (NLR) for estimating soil thermal diffusivity (KD), moreover was to select the best predictor variables used for determination of PTFs.Materials and Methods:Soil thermal diffusivity was measured at different values of water content using Kondratieff method. The parameters of th
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16

Duara, Dr Bijit Kumar, Dr Banani, and Dr Rupak Baishya. "Early Orientation of Preclinical Mbbs Students in Clinicoradiological Skills." International Journal of Medical Science and Clinical invention 7, no. 10 (2020): 5053–59. http://dx.doi.org/10.18535/ijmsci/v7i10.02.

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As per GMER 2019, the goal of medical education is to creat IMG , who is clinician of first contact ,leader ,communicator,Life long learner and Professional .Basic science (Anatomy ) is the corner stone of Radiodiagnostic principles .Early Clinico Diagnostic (Radiological) Exposure (ECDE ) ensures well integrated knowledge of applied Anatomy. Aims of the study were to assess influence of ECDE on students ,perception of students and faculties about utility of ECDE and to improve self directed learning in students. After obtaining administrative approval ,participating Faculties were selected an
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17

Yadav, Shiv Kumar, Bhola Nath, Masroof H. Khan, and A. R. Piyush. "Perception of Medical Faculties Towards Implementation of New MBBS Curriculum as per Graduate Medical Education Regulations (GMER) 2019: A CISP Workshop Findings." Journal of Research in Medical Education & Ethics 9, no. 3 (2019): 204. http://dx.doi.org/10.5958/2231-6728.2019.00036.2.

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18

Chen, Hongmeng, Zeyu Wang, Wenquan Gao, Hanwei Sun, Yaobing Lu, and Yachao Li. "Knowledge-Aided Ground Moving Target Relocation for Airborne Dual-Channel Wide-Area Radar by Exploiting the Antenna Pattern Information." Remote Sensing 13, no. 22 (2021): 4724. http://dx.doi.org/10.3390/rs13224724.

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This paper addresses the problem of ground moving target relocation (GMTR) for airborne dual-channel wide-area radar systems. The monopulse technique can be utilized to perform GMTR. However, in real conditions, the GMTR performance degrades greatly due to the effect of channel mismatch. To tackle this problem, prior knowledge of the antenna pattern information is fully utilized to improve the GMTR performance, and a knowledge-aided GMTR algorithm (KA-GMTR) for airborne dual-channel wide-area radar is proposed in this paper. First, the GMTR model for the two receiving channels is analyzed. The
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19

Lei, Yuxiao, Weitang Wang, Yibin Yao, and Liang Zhang. "A COSMIC-2-Based Global Mean TEC Model and Its Application to Calibrating IRI-2020 Global Ionospheric Maps." Remote Sensing 17, no. 13 (2025): 2322. https://doi.org/10.3390/rs17132322.

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While space weather indices (e.g., F10.7, Dst index) are commonly employed to characterize ionospheric activity levels, the Global Mean Electron Content (GMEC) provides a more direct and comprehensive indicator of the global ionospheric state. This metric demonstrates greater potential than space weather indices for calibrating empirical ionospheric models such as IRI-2020. The COSMIC-2 constellation enables continuous, all-weather global ionospheric monitoring via radio occultation, unimpeded by land–sea distribution constraints, with over 8000 daily occultation events suitable for GMEC model
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20

Guo, Yu. "When Is a Genuine Multipartite Entanglement Measure Monogamous?" Entropy 24, no. 3 (2022): 355. http://dx.doi.org/10.3390/e24030355.

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A crucial issue in quantum communication tasks is characterizing how quantum resources can be quantified and distributed over many parties. Consequently, entanglement has been explored extensively. However, there are few genuine multipartite entanglement measures and whether it is monogamous is so far unknown. In this work, we explore the complete monogamy of genuine multipartite entanglement measure (GMEM) for which, at first, we investigate a framework for unified/complete GMEM according to the unified/complete multipartite entanglement measure we proposed in 2020. We find a way of inducing
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21

Lee, Ji-hyun, Heon-seock Cynn, Sil-ah Choi, Tae-lim Yoon, and Hyo-jung Jeong. "Effects of Different Hip Rotations on Gluteus Medius and Tensor Fasciae Latae Muscle Activity During Isometric Side-Lying Hip Abduction." Journal of Sport Rehabilitation 22, no. 4 (2013): 301–7. http://dx.doi.org/10.1123/jsr.22.4.301.

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Context:Gluteus medius (Gmed) weakness is associated with some lower-extremity injuries. People with Gmed weakness might compensate by activating the tensor fasciae latae (TFL). Different hip rotations in the transverse plane may affect Gmed and TFL muscle activity during isometric side-lying hip abduction (SHA).Objectives:To compare Gmed and TFL muscle activity and the Gmed:TFL muscle-activity ratio during SHA exercise with 3 different hip rotations.Design:The effects of different hip rotations on Gmed, TFL, and the Gmed:TFL muscle-activity ratio during isometric SHA were analyzed with 1-way,
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O’Sullivan, Kieran, Ellen Herbert, David Sainsbury, Karen McCreesh, and Amanda Clifford. "No Difference in Gluteus Medius Activation in Women With Mild Patellofemoral Pain." Journal of Sport Rehabilitation 21, no. 2 (2012): 110–18. http://dx.doi.org/10.1123/jsr.21.2.110.

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Context:The gluteus medius (Gmed) is proposed to consist of 3 functional subdivisions (anterior, middle, and posterior). Gmed weakness and dysfunction have been implicated in numerous lower extremity disorders, including patellofemoral pain syndrome (PFPS). PFPS is a knee condition that frequently occurs in females and is associated with activities such as squatting and stair climbing. There is a lack of evidence for the role of the subdivisions of the Gmed in females with and without PFPS.Objective:To compare muscle activation in the 3 Gmed subdivisions during 4 weight-bearing exercises in wo
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McBeth, Joseph M., Jennifer E. Earl-Boehm, Stephen C. Cobb, and Wendy E. Huddleston. "Hip Muscle Activity During 3 Side-Lying Hip-Strengthening Exercises in Distance Runners." Journal of Athletic Training 47, no. 1 (2012): 15–23. http://dx.doi.org/10.4085/1062-6050-47.1.15.

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Context: Lower extremity overuse injuries are associated with gluteus medius (GMed) weakness. Understanding the activation of muscles about the hip during strengthening exercises is important for rehabilitation. Objective: To compare the electromyographic activity produced by the gluteus medius (GMed), tensor fascia latae (TFL), anterior hip flexors (AHF), and gluteus maximus (GMax) during 3 hip-strengthening exercises: hip abduction (ABD), hip abduction with external rotation (ABD-ER), and clamshell (CLAM) exercises. Design: Controlled laboratory study. Setting: Laboratory. Patients or Other
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MacNeil, Jennifer L., Michelle Adams, and Tony R. Walker. "Evaluating the Efficacy of Sustainability Initiatives in the Canadian Port Sector." Sustainability 14, no. 1 (2021): 373. http://dx.doi.org/10.3390/su14010373.

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Maritime ports are critical nodes in the Canadian resource-based economy that can have significant environmental impacts near coastal communities and marine ecosystems. To address these impacts, Canadian Port Authorities (CPAs) assess their environmental performance using the Green Marine Environmental Program (GMEP). Reliance on this program necessitates its evaluation as an effective initiative to address sustainability in its broader context. An analysis was performed to identify links between United Nations Sustainable Development Goals (UN SDG) targets relevant to the Canadian Port Sector
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Li, Zhengzheng, Yan Zhang, and Scott E. Giangrande. "Rainfall-Rate Estimation Using Gaussian Mixture Parameter Estimator: Training and Validation." Journal of Atmospheric and Oceanic Technology 29, no. 5 (2012): 731–44. http://dx.doi.org/10.1175/jtech-d-11-00122.1.

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Abstract This study develops a Gaussian mixture rainfall-rate estimator (GMRE) for polarimetric radar-based rainfall-rate estimation, following a general framework based on the Gaussian mixture model and Bayes least squares estimation for weather radar–based parameter estimations. The advantages of GMRE are 1) it is a minimum variance unbiased estimator; 2) it is a general estimator applicable to different rain regimes in different regions; and 3) it is flexible and may incorporate/exclude different polarimetric radar variables as inputs. This paper also discusses training the GMRE and the sen
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Valková, Veronika, Hana Ďúranová, Lucia Galovičová, Jana Štefániková, Nenad Vukovic, and Miroslava Kačániová. "The Citrus reticulata essential oil: evaluation of antifungal activity against penicillium species related to bakery products spoilage." Potravinarstvo Slovak Journal of Food Sciences 15 (October 28, 2021): 1112–19. http://dx.doi.org/10.5219/1695.

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Fungal food spoilage plays a key role in the deterioration of food products, and finding a suitable natural preservative can solve this problem. Therefore, antifungal activity of green mandarin (Citrus reticulata) essential oil (GMEO) in the vapor phase against the growth of Penicillium (P.) expansum and P. chrysogenum inoculated on wheat bread (in situ experiment) was investigated in the current research. The volatile compounds of the GMEO were analyzed by a gas chromatograph coupled to a mass spectrometer (GC–MS), and its antioxidant activity was determined by testing free radical-scavenging
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Kivle, Kjetil, Elisabeth S. Lindland, Knut Erik Mjaaland, Svein Svenningsen, and Lars Nordsletten. "Gluteal atrophy and fatty infiltration in end-stage osteoarthritis of the hip." Bone & Joint Open 2, no. 1 (2021): 40–47. http://dx.doi.org/10.1302/2633-1462.21.bjo-2020-0179.r1.

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Aims The gluteus minimus (GMin) and gluteus medius (GMed) have unique structural and functional segments that may be affected to varying degrees, by end-stage osteoarthritis (OA) and normal ageing. We used data from patients with end-stage OA and matched healthy controls to 1) quantify the atrophy of the GMin and GMed in the two groups and 2) describe the distinct patterns of the fatty infiltration in the different segments of the GMin and GMed in the two groups. Methods A total of 39 patients with end-stage OA and 12 age- and sex frequency-matched healthy controls were prospectively enrolled
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Zaworski, Kamil, Joanna Baj-Korpak, Anna Kręgiel-Rosiak, and Krystyna Gawlik. "Effects of Kinesio Taping and Rigid Taping on Gluteus Medius Muscle Activation in Healthy Individuals: A Randomized Controlled Study." International Journal of Environmental Research and Public Health 19, no. 22 (2022): 14889. http://dx.doi.org/10.3390/ijerph192214889.

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Background: Gluteus medius muscle (GMed) dysfunctions may be associated with pain and functional problems in the lumbar spine and lower limbs. The study sought to assess the effects of applying kinesio taping (KT) and rigid taping (RT) on GMed in the dominant leg of healthy individuals. Furthermore, an attempt was made to indicate which of the applied exercises brought about the greatest activation of GMed. Methods: The study included 90 individuals, with an average age of 21.79. The participants were randomly assigned to one of three groups: kinesio tape (KT), rigid tape (RT) and placebo tape
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29

Gilfeather, Daniel, Grant Norte, Christopher D. Ingersoll, and Neal R. Glaviano. "Central Activation Ratio Is a Reliable Measure for Gluteal Neuromuscular Function." Journal of Sport Rehabilitation 29, no. 7 (2020): 956–62. http://dx.doi.org/10.1123/jsr.2019-0243.

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Context: Central activation ratio (CAR) is a common outcome measure used to quantify gross neuromuscular function of the quadriceps using the superimposed burst technique, yet this outcome measure has not been validated in the gluteal musculature. Objective: To quantify gluteus medius (GMed) and gluteus maximus (GMax) CAR in a healthy population and evaluate its validity and reliability over a 1-week period. Design: Descriptive. Setting: Laboratory. Patients or Other Participants: A total of 20 healthy participants (9 males and 11 females; age 22.2 [1.4] y, height 173.4 [11.1] cm, mass 84.8 [2
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Zhou, Jian, Feng Lan Li, Li Yun Su, and Rui Hua Liu. "Copyright Protector for Digital Library with GMFR." Advanced Materials Research 694-697 (May 2013): 2241–46. http://dx.doi.org/10.4028/www.scientific.net/amr.694-697.2241.

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Copyright information is modulated and embedded into the wavelet domain of original image of digital literature in digital library with generalized matched filter receiver (GMFR), which is an optimum receiver. Because of the good performances of de-noising and whitening to non-stationary noise of wavelet transformation, a GMFR scheme of copyright protection for digital library only can be detected by authorized people. Numerical results show that the proposed copyright protector with GMFR in wavelet domain is effect and is also better than some traditional methods.
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Robinson, Matthew, Grant E. Norte, Amanda Murray, and Neal R. Glaviano. "Feasibility of Superimposed Neuromuscular Electrical Stimulation to the Gluteus Medius During a Resistance Training Program." Journal of Sport Rehabilitation 31, no. 3 (2022): 279–85. http://dx.doi.org/10.1123/jsr.2021-0095.

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Context: Gluteus medius (GMed) weakness is a common impairment seen across multiple lower-extremity pathologies. Greater GMed weakness is moderately associated with greater frontal plane motion, often termed dynamic knee valgus during functional tasks which may increase risk of lower-extremity injury. Neuromuscular electrical stimulation (NMES) superimposed to targeted muscles has emerged in clinical practice; however, NMES superimposed to the GMed in unknown. It is essential to assess the safety, credibility, and expectancy of NMES superimposed to the GMed prior to implementation in clinical
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Kaul, Sunil, John A. Blackford, Jun Chen, Vasily V. Ogryzko, and S. Stoney Simons. "Properties of the Glucocorticoid Modulatory Element Binding Proteins GMEB-1 and -2: Potential New Modifiers of Glucocorticoid Receptor Transactivation and Members of the Family of KDWK Proteins." Molecular Endocrinology 14, no. 7 (2000): 1010–27. http://dx.doi.org/10.1210/mend.14.7.0494.

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Abstract An important component of glucocorticoid steroid induction of tyrosine aminotransferase (TAT) gene expression is the glucocorticoid modulatory element (GME), which is located at −3.6 kb of the rat TAT gene. The GME both mediates a greater sensitivity to hormone, due to a left shift in the dose-response curve of agonists, and increases the partial agonist activity of antiglucocorticoids. These properties of the GME are intimately related to the binding of a heteromeric complex of two proteins (GMEB-1 and -2). We previously cloned the rat GMEB-2 as a 67-kDa protein. We now report the cl
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Meng, Xia, Anxin Wang, Guojun Zhang, et al. "Analytical validation of GMEX rapid point-of-care CYP2C19 genotyping system for the CHANCE-2 trial." Stroke and Vascular Neurology 6, no. 2 (2021): 274–79. http://dx.doi.org/10.1136/svn-2021-000874.

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Background and purposeRapid genotyping is useful for guiding early antiplatelet therapy in patients with high-risk nondisabling ischaemic cerebrovascular events (HR-NICE). Conventional genetic testing methods used in CYP2C19 genotype-guided antiplatelet therapy for patients with HR-NICE did not satisfy the needs of the Clopidogrel in High-Risk Patients with Acute Nondisabling Cerebrovascular Events (CHANCE)-2 trial. Therefore, we developed the rapid-genotyping GMEX (point-of-care) system to meet the needs of the CHANCE-2 trial.MethodsHealthy individuals and patients with history of cardiovascu
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Fatima, Arooj, Humaira Jami, and Khadija Muzzaffer. "TRANSLATION AND VALIDATION OF GENDER MINORITY STRESS & RESILIENCE SCALE." Pakistan Journal of Social Research 04, no. 03 (2022): 530–40. http://dx.doi.org/10.52567/pjsr.v4i03.743.

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The purpose of the present study was to translate Gender Minority Stress &amp; Resilience Scale (GMSR; Testa, 2014) into Urdu language for construct validity of the scale for gender nonconforming individuals living in Pakistani culture. This purpose was accomplished in two phases. In the first phase, the GMSR Scale was translated in to Urdu language by following the steps of back translation method suggested by Brislin (1972).To establish the construct validity of GMSR Scale, data was collected in two phases, first from transgender community to determine convergent validity of the scale, in se
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35

McDermott, R. H., and M. Butler. "Uptake of glutamate, not glutamine synthetase, regulates adaptation of mammalian cells to glutamine-free medium." Journal of Cell Science 104, no. 1 (1993): 51–58. http://dx.doi.org/10.1242/jcs.104.1.51.

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Two cell lines (McCoy and MDCK) were studied in an attempt to understand the metabolic changes associated with adaptation to glutamine-free medium (GMEM + gmate). McCoy cells assumed normal growth rates after 2–3 passages in this medium whereas MDCK cells showed no growth in GMEM + gmate. The glutamine synthetase (GS) activity of both cell lines was elevated (up to × 9) as glutamine was depleted from normal media (GMEM + gmine). The high activity of GS was maintained during McCoy cell growth in GMEM + gmate. However, there was no apparent significant difference between the two cell lines in th
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Williams, Katherine V., Bo Zhai, John F. Alcorn, et al. "99. Immune Responses to Influenza Vaccines in Children and Young Adults." Open Forum Infectious Diseases 8, Supplement_1 (2021): S62—S63. http://dx.doi.org/10.1093/ofid/ofab466.099.

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Abstract Background Immune responses to influenza vaccines (IV) are influenced by pre-existing antibodies to vaccine components. Immune responses to vaccines were evaluated following vaccination with quadrivalent egg-based live-attenuated influenza vaccine (LAIV4) and cell-culture inactivated influenza vaccine (ccIIV4). Methods Racially diverse (48.0% non-white), healthy, community-dwelling children and young adults aged 4-21 years (median, 18.3 years) were randomized 1:1 in blocks of 4 to receive intramuscular ccIIV4 (Flucelvax: n=100) or nasal LAIV4 (FluMist: n=98); baseline demographics wer
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Milinčić, Danijel D., Aleksandar Ž. Kostić, Steva Lević, et al. "Goat’s Milk Powder Enriched with Red (Lycium barbarum L.) and Black (Lycium ruthenicum Murray) Goji Berry Extracts: Chemical Characterization, Antioxidant Properties, and Prebiotic Activity." Foods 14, no. 1 (2024): 62. https://doi.org/10.3390/foods14010062.

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The current trend in food innovations includes developing products containing plant ingredients or extracts rich in bioactive compounds. This study aimed to prepare and characterize skimmed thermally treated goat’s milk powders enriched with lyophilized fruit extracts of Lycium ruthenicum Murray (GMLR) and Lycium barbarum L. (GMLB). Proximate analysis, ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS), Fourier transform infrared spectroscopy using attenuated total reflection (FTIR-ATR), and electrophoretic analysis were assessed. Tota
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Wu, Nannan, Yejun Xu, Lizhong Xu, and Huimin Wang. "The graph model for conflict resolution with consensus fuzzy preferences and its application to environmental sustainable development." Journal of Intelligent & Fuzzy Systems 39, no. 5 (2020): 6721–31. http://dx.doi.org/10.3233/jifs-190990.

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Conflict of environmental sustainable development as a common phenomenon can be seen everywhere in life. To capture consensus problems of decision makers (DMs) in conflict, a consensus and non-consensus fuzzy preference relation (FPR) matrix is proposed to the framework of the Graph Model for Conflict Resolution (GMCR). Concentrating on the case of two DMs within GMCR paradigm, four standard fuzzy solution concepts are developed into eight fuzzy stability definitions which can fully represent DMs’ behavior characteristics of win-win and self-interested. To demonstrate how the novel GMCR method
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Leoutsakos, Jeannie-Marie S., Dingfen Han, Michelle M. Mielke, et al. "Effects of general medical health on Alzheimer's progression: the Cache County Dementia Progression Study." International Psychogeriatrics 24, no. 10 (2012): 1561–70. http://dx.doi.org/10.1017/s104161021200049x.

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ABSTRACTBackground: Several observational studies have suggested a link between health status and rate of decline among individuals with Alzheimer's disease (AD). We sought to quantify the relationship in a population-based study of incident AD, and to compare global comorbidity ratings to counts of comorbid conditions and medications as predictors of AD progression.Methods: This was a case-only cohort study arising from a population-based longitudinal study of memory and aging, in Cache County, Utah. Participants comprised 335 individuals with incident AD followed for up to 11 years. Patient
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An, Zhaohui, Xueyao Zhang, Charles B. Bott, and Zhi-Wu Wang. "Long-Term Stability of Nitrifying Granules in a Membrane Bioreactor without Hydraulic Selection Pressure." Processes 9, no. 6 (2021): 1024. http://dx.doi.org/10.3390/pr9061024.

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To understand the long-term stability of nitrifying granules in a membrane bioreactor (GMBR), a membrane module was submerged in an airlift reactor to eliminate the hydraulic selection pressure that was believed to be the driving force of aerobic granulation. The long-term monitoring results showed that the structure of nitrifying granules could remain stable for 305 days in the GMBR without hydraulic selection pressure; however, the majority of the granule structure was actually inactive due to mass diffusion limitation. As a consequence, active biomass free of mass diffusion limitation only
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van der Weyden, Megan Sax, Joel Martin, Jose Rodriguez, and Ali Boolani. "An Intense Bout of Acute Aerobic Exercise, but Not a Carbohydrate Supplement, Improves Cognitive Task Performance in a Sample of Black, Indigenous, and People of Color (BIPOC) Student Athletes." Sports 11, no. 4 (2023): 88. http://dx.doi.org/10.3390/sports11040088.

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Background: There are contradictory findings in the literature on whether an acute bout of aerobic exercise leads to a post-exercise improvement in cognitive function (CF). Moreover, participants used in the published literature are not representative of the racial make-up of sport or tactical populations. Methods: A randomized crossover design was incorporated, with participants randomly consuming water or a carbohydrate sports drink within the first 3 min of a graded maximal exercise test (GMET) conducted in a laboratory. Twelve self-identified African American participants, (seven males, fi
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RAHMAWATI, FARDILLA, KHAIRIL ANWAR NOTODIPUTRO, and KUSMAN SADIK. "Classification of household poverty in West Java using the generalized mixed-effects trees model." Jurnal Natural 23, no. 3 (2023): 209–19. http://dx.doi.org/10.24815/jn.v23i3.33079.

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Dealing with fixed effects and random effects can be accomplished by combining statistical modeling and machine learning techniques. This paper discusses the modeling of fixed effects and random effects using a statistical machine-learning approach. We used the generalized mixed-effects trees (GMET), a tree-based mixed-effect model for dealing with response variables that belong to the exponential family of distributions. In this study, both simulation and actual/empirical data utilized the GMET method to discover data conditions that were appropriate for employing this approach. The simulatio
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Spiker, Andrea, Megan Baughman, and Donna Blankenbaker. "EP5.28 Creating an MRI Classification System for Hip Abductor Musculature Atrophy." Journal of Hip Preservation Surgery 12, Supplement_1 (2025): i90. https://doi.org/10.1093/jhps/hnaf011.290.

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Abstract Background: No standardized classification system exists for fatty infiltration of hip abductors, though preoperative fatty infiltration correlates with postoperative outcomes in abductor tendon repairs. Objective: We aimed to create a simple, reliable, and reproducible MRI classification system for fatty infiltration specific to hip abductors and examine the correlation between fatty infiltration grades and hip pathology. Methods: We retrospectively identified 100 patients who underwent bony pelvic MRI with no infection, fracture, tumor, or prior history of hip surgery. Using these i
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Zhang, Jing, Xiaoxia Liu, Yichen Liu, et al. "Molecular Characterization of Primary Juvenile Hormone Responders Methoprene-Tolerant (Met) and Krüppel Homolog 1 (Kr-h1) in Grapholita molesta (Lepidoptera: Tortricidae) with Clarification of Their Roles in Metamorphosis and Reproduction." Journal of Economic Entomology 112, no. 5 (2019): 2369–80. http://dx.doi.org/10.1093/jee/toz155.

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AbstractMethoprene-tolerant (Met) is a putative JH intracellular receptor that transduces JH signal by activation of the inducible Krüppel homolog 1 (Kr-h1). We analyzed the gene sequences of Met and Kr-h1 and their patterns of expression in Grapholita molesta (Busck) immature and adult stages in order to better understand the roles of these primary JH responders in regulating the metamorphosis and reproduction of this global pest of fruit crops. The deduced amino acid sequences of both GmMet and GmKr-h1 were highly homologous to those of other Lepidoptera, especially the cotton bollworm, Heli
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Yin, Chongxin, Huichun Xie, Guigong Geng, et al. "Identification of Key Enzymes and Genes Modulating L-Ascorbic Acid Metabolism During Fruit Development of Lycium chinense by Integrating Metabolome, Transcriptome, and Physiological Analysis." International Journal of Molecular Sciences 25, no. 21 (2024): 11394. http://dx.doi.org/10.3390/ijms252111394.

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Lycium chinense is acknowledged for its substantial nutritional benefits, particularly attributed to the high levels of ascorbic acid (AsA) found in its fruits. The “Mengqi No.1” variety of L. chinense, which is cultivated in Qinghai, is known for its high yield and exceptional quality. We utilized the “Mengqi No.1” variety as experimental materials and combined metabolomic, transcriptomic, and physiological analyses to investigate the metabolites, genes, and enzymes related to AsA metabolism in L. chinense fruits. The results revealed nine differential metabolites associated with AsA metaboli
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Sutradhar, Santosh C., William W. B. Wang, Katia Schlienger, et al. "Comparison of the Levels of Immunogenicity and Safety of Zostavax in Adults 50 to 59 Years Old and in Adults 60 Years Old or Older." Clinical and Vaccine Immunology 16, no. 5 (2009): 646–52. http://dx.doi.org/10.1128/cvi.00407-08.

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ABSTRACT Zostavax has been shown to be efficacious in the prevention of herpes zoster and generally well tolerated in clinical trials among subjects 60 years old or older. This prespecified combined analysis from two studies compares the levels of immunogenicity and safety of Zostavax in subjects 50 to 59 years old versus those in subjects ≥60 years old. Varicella-zoster virus (VZV) antibody (Ab) titers were measured by glycoprotein enzyme-linked immunosorbent assay at baseline and 4 weeks postvaccination. Noninferiority was evaluated by estimated geometric mean severalfold rise (GMFR) ratio (
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Marlink, Katie L., Kathy D. Bacon, Brett C. Sheppard, et al. "Effects ofHelicobacter pylorion intracellular Ca2+signaling in normal human gastric mucous epithelial cells." American Journal of Physiology-Gastrointestinal and Liver Physiology 285, no. 1 (2003): G163—G176. http://dx.doi.org/10.1152/ajpgi.00257.2002.

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In stomach, Helicobacter pylori ( Hp) adheres to gastric mucous epithelial cells (GMEC) and initiates several different signal transduction events. Alteration of intracellular Ca2+concentration ([Ca2+]i) is an important signaling mechanism in numerous bacteria-host model systems. Changes in [Ca2+]iinduced by Hp in normal human GMEC have not yet been described; therefore, we examined effects of Hp on [Ca2+]iin normal human GMEC and a nontransformed GMEC line (HFE-145). Cultured cells were grown on glass slides, porous filters, or 96-well plates and loaded with fura 2 or fluo 4. Hp wild-type str
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Zarei, Vahhab, Sharon C. Yson, Joan E. Bechtold, and Jonathan N. Sembrano. "Predicting the Effect of Bilateral Pelvic Osteotomy on Sagittal Alignment Correction and Surrounding Muscles: A Mathematical Model." Advances in Orthopedics 2019 (February 3, 2019): 1–8. http://dx.doi.org/10.1155/2019/3041359.

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Study Design. Mathematical Model. Objectives. To investigate the relationship between pelvic osteotomy opening angle (OA) and its effect on spinopelvic sagittal parameters as well as the resting length of surrounding muscles. Methods. Predictive equations correlating OA with spinopelvic parameters were derived using geometric relationships. A geometric model calculated spinopelvic parameters (SVA, pelvic incidence [PI], PT, and T1 pelvic angle [TPA]) produced by progressively increasing the OA. These values were compared to optimal balance criteria in the literature. Four muscles crossing the
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Rutten, M. J., P. J. Dempsey, C. A. Luttropp, et al. "Identification of an EGF/TGF-alpha receptor in primary cultures of guinea pig gastric mucous epithelial cells." American Journal of Physiology-Gastrointestinal and Liver Physiology 270, no. 4 (1996): G604—G612. http://dx.doi.org/10.1152/ajpgi.1996.270.4.g604.

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Binding and localization of transforming growth factor-alpha (TGF-alpha) and epidermal growth factor (EGF) were assessed using in vitro primary cultures of guinea pig gastric mucous epithelial cells (GMEC). GMEC were isolated and cultured in six-well plates with Dulbecco's modified Eagle's medium + 10% serum and then changed to serum-free medium for 24 h for binding studies. The binding time course of 125I-labeled EGF and 125I-TGF-alpha in GMEC cultures at 4 degrees C was saturable, reaching a plateau within 4-6 h. Competition-binding curves revealed that the amount of unlabeled EGF and TGF-al
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Unnikrishnan, Poornima, Kumaraswamy Ponnambalam, and Keith W. Hipel. "Conflict Resolution of Parambikulam-Aliyar Project (PAP), India Using the Graph Model for Conflict Resolution." Water 17, no. 5 (2025): 690. https://doi.org/10.3390/w17050690.

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This study employs the Graph Model for Conflict Resolution (GMCR) to systematically analyze and evaluate potential solutions to disputes arising from the Parambikulam-Aliyar Project (PAP) agreement in India. By incorporating hydrological analysis in the study, the research assesses the potential impacts of proposed solutions on water demand. The GMCR methodology is applied through a comprehensive decision support system (GMCR II), involving the identification of decision-makers, options, and preferences, followed by the development of a conflict resolution model. The analysis is based on a tho
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