Log in

Relevant bibliographies by topics / GMTS / Journal articles

To see the other types of publications on this topic, follow the link: GMTS.

Journal articles on the topic 'GMTS'

Author: Grafiati

Published: 9 October 2021

Last updated: 30 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'GMTS.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Raniak, Andrej, and Zita Izakovičová. "Global Megatrends Impacts on the Landscape, Analysis Based on Key Drivers of the Megatrends and Landscape Change: Case Study of Danubian Lowland, Slovakia." Ekológia (Bratislava) 43, no. 2 (2024): 183–91. https://doi.org/10.2478/eko-2024-0019.

Full text

Abstract:

Abstract Global megatrends (GMTs) reshape landscapes worldwide, posing challenges for sustainability. This study delves into the complex interplay between GMTs and landscape changes in the Danube Lowland region of Slovakia, a microcosm of broader trends. Leveraging the concept of representative potential geoecosystems (REPGES), we assess historical landscape transformations and correlate them with key GMT drivers. Results reveal significant urban expansion linked to GMT2, primarily impacting the Bratislava area. Simultaneously, GMT5-driven economic growth manifests in agricultural land expansi

APA, Harvard, Vancouver, ISO, and other styles

2

Xie, Zhiqiang, Jiangjiao Li, Xue Wang, et al. "The Safety and Immunogenicity of a 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine (CRM197/TT) in Infants: A Double-Blind, Randomized, Phase III Trial." Vaccines 12, no. 12 (2024): 1417. https://doi.org/10.3390/vaccines12121417.

Full text

Abstract:

Objectives: This study aimed to evaluate the immunogenicity and safety of a 13-valent pneumococcal polysaccharide conjugate vaccine (CRM197/TT) (PCV13i) in infants. Methods: A total of 1200 infants were randomly assigned to either the experimental PCV13i group or the control PCV13 group in a 1:1 ratio. Each group received a three-dose series of the vaccine at 2, 4, and 6 months of age, followed by a booster dose at 12–15 months. Blood samples were collected before and 30 days after both primary and booster vaccinations. The primary immunogenicity endpoints were the seropositive rate and the ge

APA, Harvard, Vancouver, ISO, and other styles

3

Dukes, Christopher W., Marine Potez, Jeffrey Lancet, et al. "Neutralizing Antibody Response following a Third Dose of the mRNA-1273 Vaccine among Cancer Patients." Vaccines 12, no. 1 (2023): 13. http://dx.doi.org/10.3390/vaccines12010013.

Full text

Abstract:

Cancer patients are at an increased risk of morbidity and mortality from SARS-CoV-2 infection and have a decreased immune response to vaccination. We conducted a study measuring both the neutralizing and total antibodies in cancer patients following a third dose of the mRNA-1273 COVID-19 vaccine. Immune responses were measured with an enzyme-linked immunosorbent assay (ELISA) and neutralization assays. Kruskal–Wallis tests were used to evaluate the association between patient characteristics and neutralization geometric mean titers (GMTs), and paired t-tests were used to compare the GMTs betwe

APA, Harvard, Vancouver, ISO, and other styles

4

Kudron, Elizabeth L., Kimberly M. Deininger, and Christina L. Aquilante. "Are Graduate Medical Trainees Prepared for the Personalized Genomic Medicine Revolution? Trainee Perspectives at One Institution." Journal of Personalized Medicine 13, no. 7 (2023): 1025. http://dx.doi.org/10.3390/jpm13071025.

Full text

Abstract:

Although the use of genomics to inform clinical care is increasing, clinicians feel underprepared to integrate personalized medicine (PM) into care decisions. The educational needs of physician residents and fellows, also known as graduate medical trainees (GMTs), have been overlooked. We administered an anonymous, web-based survey to all GMTs participating in training programs affiliated with our institution to evaluate their knowledge, skills, and attitudes toward PM. Of the 1190 GMTs contacted, 319 (26.8%) returned surveys. Most (88.4%) respondents reported receiving PM education in the pas

APA, Harvard, Vancouver, ISO, and other styles

5

Zhao, Chenming, Xiaoyue Yang, Wenqiang Jiang, Guifen Zhang, and Dongfang Ma. "FgGmtB Plays an Important Role in Growth, Reproduction, Virulence and Deoxynivalenol Biosynthesis of Fusarium graminearum." Journal of Fungi 10, no. 3 (2024): 208. http://dx.doi.org/10.3390/jof10030208.

Full text

Abstract:

GDP-mannose transporters (GMTs) have been implicated in the virulence of some important pathogenic fungi, and guanosine diphosphate (GDP) mannose transporters transport GDP-mannose from the cytosol to the Golgi lumen prior to mannosylation, where mannose attaches to the modified protein. GMTs could be potential targets for new antifungal drugs, as disruption of any step in GDP-mannose biosynthesis can affect fungal viability, growth, or virulence. To date, the GDP-mannose transporter has been extensively studied in yeast, but its biological function in fungi, particularly F. graminearum, is st

APA, Harvard, Vancouver, ISO, and other styles

6

Domachowske, Joseph B., Veronique Bianco, Ana Ceballos, et al. "2855. Respiratory Syncytial Virus Neutralizing Antibodies in Cord Blood and Serum from Infants up to 2 Years of Age in a Multinational Prospective Study." Open Forum Infectious Diseases 6, Supplement_2 (2019): S74—S75. http://dx.doi.org/10.1093/ofid/ofz359.160.

Full text

Abstract:

Abstract Background Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infections (LRTI) during infancy worldwide. High cord blood (CB) concentrations of anti-RSV neutralizing antibody (nAb) may attenuate, delay, or prevent infant infection. We report RSV A and B nAb concentrations in CB and serum from a birth cohort at different time points through 2 years of age. Methods Between 2013 and 2017, newborns from 8 countries were studied prospectively from birth to 2 years of age (NCT01995175). CB was collected at birth for the entire cohort. A subcohort of child

APA, Harvard, Vancouver, ISO, and other styles

7

Negru, Radu, Liviu Marşavina, and Hannelore Filipescu. "Evaluation of Generalized MTS Criterion for Mixed-Mode Fracture of Polyurethane Materials." Key Engineering Materials 577-578 (September 2013): 117–20. http://dx.doi.org/10.4028/www.scientific.net/kem.577-578.117.

Full text

Abstract:

Using the asymmetric semi-circular bend specimen (ASCB) a set of mixed-mode fracture tests were carried out in the full range from pure mode I to pure mode II. The tests were conducted on two polyurethane materials characterized by different properties. The fracture parameters were obtained from experiments and are compared with the predictions based on the generalized MTS criterion (GMTS). The agreement between the experimental results and those predicted based on the GMTS criterion is discussed finally.

APA, Harvard, Vancouver, ISO, and other styles

8

Faella, Marco, and Gennaro Parlato. "Reachability Games Modulo Theories with a Bounded Safety Player." Proceedings of the AAAI Conference on Artificial Intelligence 37, no. 5 (2023): 6330–37. http://dx.doi.org/10.1609/aaai.v37i5.25779.

Full text

Abstract:

Solving reachability games is a fundamental problem for the analysis, verification, and synthesis of reactive systems. We consider logical reachability games modulo theories (in short, GMTs), i.e., infinite-state games whose rules are defined by logical formulas over a multi-sorted first-order theory. Our games have an asymmetric constraint: the safety player has at most k possible moves from each game configuration, whereas the reachability player has no such limitation. Even though determining the winner of such a GMT is undecidable, it can be reduced to the well-studied problem of checking

APA, Harvard, Vancouver, ISO, and other styles

9

Miarka, Petr, Robin Janssen, Stanislav Seitl, and Wouter de Corte. "A Comparison of the Fracture Behaviour of Various Concrete Grades under Mixed Mode I/II Loading." Key Engineering Materials 827 (December 2019): 228–33. http://dx.doi.org/10.4028/www.scientific.net/kem.827.228.

Full text

Abstract:

The Brazilian disc test with central notch is widely used to evaluate mixed mode I/II fracture resistance of brittle materials such as rocks and concrete. An analytical evaluation is used based on the maximum tangential stress (MTS) criterion and the generalised maximum tangential stress (GMTS) criterion. In this contribution two concrete types, a C 50/60 and a high strength concrete, were compared using the GMTS criterion. Also, the influence of critical distance rC on the fracture resistance under the mixed mode I/II was studied.

APA, Harvard, Vancouver, ISO, and other styles

10

BORROW, R., A. J. FOX, P. C. RICHMOND, et al. "Induction of immunological memory in UK infants by a meningococcal A/C conjugate vaccine." Epidemiology and Infection 124, no. 3 (2000): 427–32. http://dx.doi.org/10.1017/s0950268899003787.

Full text

Abstract:

The induction of immunological memory to serogroup A and C polysaccharides in UK infants immunized with three doses of a meningococcal A/C oligosaccharide CRM197 conjugate vaccine was investigated. Forty UK infants vaccinated previously with three doses of a meningococcal A/C oligosaccharide-CRM197 conjugate vaccine at 2, 3 and 4 months of age, were revaccinated at a mean age of 145·6 weeks with either a 10 or 50 μg dose of licensed meningococcal A/C polysaccharide vaccine. Serogroup-specific antibody and serum bactericidal antibody (SBA) responses were measured by enzyme-linked immunosorbent

APA, Harvard, Vancouver, ISO, and other styles

11

Kourkounti, S., N. Mavrianou, Va Paparizos, et al. "Immune response to hepatitis a vaccination in HIV-infected men in Greece." International Journal of STD & AIDS 23, no. 7 (2012): 464–67. http://dx.doi.org/10.1258/ijsa.2011.011297.

Full text

Abstract:

HIV-infected patients are at increased risk for acquiring hepatitis A virus (HAV) infection. We evaluated the seroconversion rate (anti-HAV antibodies ≥ 20 mIU/ml) and the geometric mean antibody titres (GMTs) in a group of 351 HIV infected men, who had received two doses of a hepatitis A vaccine. We analysed blood samples collected at one, six, 12 and 18 months following the administration of the second dose of the vaccine. The seroconversion rate one month after the second dose of the vaccine was 74.4% (260/351). At month 18 after the end of vaccination, 56.1 % of the subjects remained serop

APA, Harvard, Vancouver, ISO, and other styles

12

Suntharasamai, Pravan, Pornthep Chanthavanich, M. J. Warrell, et al. "Purified Vero cell rabies vaccine and human diploid cell strain vaccine: comparison of neutralizing antibody responses to post-exposure regimens." Journal of Hygiene 96, no. 3 (1986): 483–89. http://dx.doi.org/10.1017/s0022172400066286.

Full text

Abstract:

SUMMARYNeutralizing antibody responses to conventional rabies post-exposure regimens of human diploid cell strain vaccine (HDCSV) and the new purified Vero cell rabies vaccine (PVRV) were compared in 58 healthy Thai veterinary students. The geometric mean titres (GMTs) of the group given HDCSV were slightly higher than those given PVRV, but on day 28 the peak GMTs of the two groups were statistically similar. The early antibody response to PVRV was unaffected by the addition of passive immunization, whereas the level of HDCSV response was reduced on day 14, so that there was no difference on t

APA, Harvard, Vancouver, ISO, and other styles

13

Li, Juan, Hui Xie, Weixin Chen, et al. "Immune Persistence against SARS-CoV-2 after Primary and Booster Immunization in Humans: A Large-Scale Prospective Cohort Study." Vaccines 10, no. 10 (2022): 1677. http://dx.doi.org/10.3390/vaccines10101677.

Full text

Abstract:

Amid the ongoing global COVID-19 pandemic, limited literature exists on immune persistence after primary immunization and the immunogenic features of booster vaccines administered at different time intervals. Therefore, this study aimed to determine the immune attenuation of neutralizing antibodies against the SARS-CoV-2 wild-type strain, and Delta and Omicron variants 12 months after the primary administration of the COVID-19 inactivated vaccine and evaluate the immune response after a booster administration at different time intervals. A total of 514 individuals were followed up after primar

APA, Harvard, Vancouver, ISO, and other styles

14

Doležalová, Kristina, Jaroslav Řídký, and Daniel Pilař. "Rhyolite grinding-milling tools in focus." Archeologické rozhledy 75, no. 2 (2023): 109–31. http://dx.doi.org/10.35686/ar.2023.9.

Full text

Abstract:

Past societies have used various raw materials for making grinding-milling tools (GMT). These included rhyolite, a hard volcanic rock with a porphyritic texture and pores, which is suitable for grinding. Thus far, no experiments have been carried out involving use-wear analysis on rhyolite grinding stones, and more specifically on Neolithic GMTs made of this raw material. Therefore, in this paper, we present an experimental program designed to investigate the development of wear from the grinding of einkorn wheat (Triticum monococcum) on rhyolite GMT replicas. To test the resulting observation

APA, Harvard, Vancouver, ISO, and other styles

15

Rennels, Margaret B., George F. Reed, Michael D. Decker, et al. "Simultaneous Administration of Haemophilus influenzae Type b Vaccine With Acellular or Whole-Cell Pertussis Vaccine: Effects on Reactogenicity and Immune Responses to Pertussis Vaccines." Pediatrics 96, no. 3 (1995): 576–79. http://dx.doi.org/10.1542/peds.96.3.576.

Full text

Abstract:

Objective. To evaluate the effect of simultaneous Haemophilus influenzae type b conjugate (Hib) vaccination on the safety and immunogenicity of selected acellular (DTaP) and whole-cell (DTP) pertussis vaccines with diphtheria and tetanus toxoids combined. Methods. Enrollment of infants into a large multicenter study of the safety and immunogenicity of 13 DTaP and 2 DTP vaccines was partially completed when the first Hib vaccine, HbOC (Haemophilus b oligosaccharide conjugate vaccine), was licensed for use in infants. Thereafter, at each immunization most infants received HbOC simultaneously wit

APA, Harvard, Vancouver, ISO, and other styles

16

Katz, Dana, Dan Sindhikara, Michael DiMattia, and Abba E. Leffler. "Potency-Enhancing Mutations of Gating Modifier Toxins for the Voltage-Gated Sodium Channel NaV1.7 Can Be Predicted Using Accurate Free-Energy Calculations." Toxins 13, no. 3 (2021): 193. http://dx.doi.org/10.3390/toxins13030193.

Full text

Abstract:

Gating modifier toxins (GMTs) isolated from venomous organisms such as Protoxin-II (ProTx-II) and Huwentoxin-IV (HwTx-IV) that inhibit the voltage-gated sodium channel NaV1.7 by binding to its voltage-sensing domain II (VSDII) have been extensively investigated as non-opioid analgesics. However, reliably predicting how a mutation to a GMT will affect its potency for NaV1.7 has been challenging. Here, we hypothesize that structure-based computational methods can be used to predict such changes. We employ free-energy perturbation (FEP), a physics-based simulation method for predicting the relati

APA, Harvard, Vancouver, ISO, and other styles

17

Rungmaitree, Supattra, Charin Thepthai, Zheng Quan Toh, et al. "Immunogenicity of a Two-Dose Human Papillomavirus Vaccine Schedule in HIV-Infected Adolescents with Immune Reconstitution." Vaccines 10, no. 1 (2022): 118. http://dx.doi.org/10.3390/vaccines10010118.

Full text

Abstract:

HIV-infected patients are at increased risk of human papillomavirus (HPV) acquisition and HPV-associated diseases. This study set out to determine whether a two-dose (2D) HPV vaccination schedule was sufficient in HIV-infected adolescents with immune reconstitution (IR) following antiretroviral treatment. Participants aged 9–15 years who had CD4 cell counts > 500 cells/mm3 and HIV-1 RNA < 40 copies/mL for at least one year were assigned to the 2D schedule, while older participants or those without IR received a three-dose (3D) schedule. Antibodies to HPV-16 and -18 were measured using a

APA, Harvard, Vancouver, ISO, and other styles

18

Omole, Tosin, Enrique Pelayo, Aaron S. Weinberg, et al. "Safety, Tolerability, and Immunogenicity of the Pneumococcal Vaccines PPSV23 or PCV15 Co-Administered with a Booster Dose of mRNA-1273 SARS-CoV-2 Vaccine in Healthy Adults ≥50 Years of Age." Vaccines 13, no. 2 (2025): 192. https://doi.org/10.3390/vaccines13020192.

Full text

Abstract:

Background/Objectives: Streptococcus pneumoniae with, or following, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been associated with increased mortality, particularly in older adults. However, vaccination can be an effective preventative measure. This Phase 3 study (NCT05158140) assessed the immunogenicity and safety of co-administering the SARS-CoV-2 vaccine mRNA-1273 with the 23-valent pneumococcal polysaccharide vaccine (PPSV23) or the 15-valent pneumococcal conjugate vaccine (PCV15). Methods: Participants were healthy adults ≥50 years of age who had previousl

APA, Harvard, Vancouver, ISO, and other styles

19

Gromer, Daniel J., Brian D. Plikaytis, Michele P. McCullough, Sonia Tandon Wimalasena, and Nadine Rouphael. "The Relationship between Immunogenicity and Reactogenicity of Seasonal Influenza Vaccine Using Different Delivery Methods." Vaccines 12, no. 7 (2024): 809. http://dx.doi.org/10.3390/vaccines12070809.

Full text

Abstract:

Vaccine immunogenicity and reactogenicity depend on recipient and vaccine characteristics. We hypothesized that healthy adults reporting higher reactogenicity from seasonal inactivated influenza vaccine (IIV) developed higher antibody titers compared with those reporting lower reactogenicity. We performed a secondary analysis of a randomized phase 1 trial of a trivalent IIV delivered by microneedle patch (MNP) or intramuscular (IM) injection. We created composite reactogenicity scores as exposure variables and used hemagglutination inhibition (HAI) titers as outcome variables. We used mixed-mo

APA, Harvard, Vancouver, ISO, and other styles

20

Dutta, Soumen, Chaiti Ray, Anup Kumar Sasmal, Yuichi Negishi, and Tarasankar Pal. "Fabrication of dog-bone shaped Au NRcore–Pt/Pdshell trimetallic nanoparticle-decorated reduced graphene oxide nanosheets for excellent electrocatalysis." Journal of Materials Chemistry A 4, no. 10 (2016): 3765–76. http://dx.doi.org/10.1039/c6ta00379f.

Full text

Abstract:

Dog-bone shaped Au NR<sub>core</sub>–Pt/Pd<sub>shell</sub> decorated reduced graphene oxide nanocomposites (GMTs) exhibit outstanding electrocatalytic activity and durability towards ethanol oxidation reaction.

APA, Harvard, Vancouver, ISO, and other styles

21

Gao, Shuai, William C. Valinsky, Nguyen Cam On, et al. "Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na+channels in nanodisc." Proceedings of the National Academy of Sciences 117, no. 25 (2020): 14187–93. http://dx.doi.org/10.1073/pnas.1922903117.

Full text

Abstract:

NaChBac, the first bacterial voltage-gated Na+(Nav) channel to be characterized, has been the prokaryotic prototype for studying the structure–function relationship of Navchannels. Discovered nearly two decades ago, the structure of NaChBac has not been determined. Here we present the single particle electron cryomicroscopy (cryo-EM) analysis of NaChBac in both detergent micelles and nanodiscs. Under both conditions, the conformation of NaChBac is nearly identical to that of the potentially inactivated NavAb. Determining the structure of NaChBac in nanodiscs enabled us to examine gating modifi

APA, Harvard, Vancouver, ISO, and other styles

22

Harsono, Sony HA, Zarkasih Anwar, and Nancy Pardede. "Comparison of seroconversion rates between low-dose intradermal and recommended dose intramuscular hepatitis B vaccination in children." Paediatrica Indonesiana 43, no. 4 (2016): 140. http://dx.doi.org/10.14238/pi43.4.2003.140-6.

Full text

Abstract:

Introduction Massive hepatitis B vaccination is expensive. Re-sults of studies showed that reduced dosage given intradermallyto adults and intramuscularly to children were able to induceseroconversion.Objective To compare the anti-HBs seroconversion (seropositiveand seroprotective) rates between intradermal low-dose of 2 mg(ID-2) and intramuscular recommended dose of 10 mg (IM-10)vaccination against hepatitis B.Methods In a randomized clinical trial, using the hepatitis B plasmavaccine, elementary school children in Tanjung Enim subdistrict,80-168 months of age, were randomly assigned to be gi

APA, Harvard, Vancouver, ISO, and other styles

23

Nygård, Mari, Alfred Saah, Christian Munk, et al. "Evaluation of the Long-Term Anti-Human Papillomavirus 6 (HPV6), 11, 16, and 18 Immune Responses Generated by the Quadrivalent HPV Vaccine." Clinical and Vaccine Immunology 22, no. 8 (2015): 943–48. http://dx.doi.org/10.1128/cvi.00133-15.

Full text

Abstract:

ABSTRACTThis quadrivalent human papillomavirus (qHPV) (HPV6, -11, -16, and -18) vaccine long-term follow-up (LTFU) study is an ongoing extension of a pivotal clinical study (FUTURE II) taking place in the Nordic region. The LTFU study was designed to evaluate the effectiveness, immunogenicity, and safety of the qHPV vaccine (Gardasil) for at least 10 years following completion of the base study. The current report presents immunogenicity data from testing samples of the year 5 LTFU visit (approximately 9 years after vaccination). FUTURE II vaccination arm subjects, who consented to being follo

APA, Harvard, Vancouver, ISO, and other styles

24

Shen, Huaizong, Dongliang Liu, Kun Wu, Jianlin Lei, and Nieng Yan. "Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins." Science 363, no. 6433 (2019): 1303–8. http://dx.doi.org/10.1126/science.aaw2493.

Full text

Abstract:

Voltage-gated sodium channel Nav1.7 represents a promising target for pain relief. Here we report the cryo–electron microscopy structures of the human Nav1.7-β1-β2 complex bound to two combinations of pore blockers and gating modifier toxins (GMTs), tetrodotoxin with protoxin-II and saxitoxin with huwentoxin-IV, both determined at overall resolutions of 3.2 angstroms. The two structures are nearly identical except for minor shifts of voltage-sensing domain II (VSDII), whose S3-S4 linker accommodates the two GMTs in a similar manner. One additional protoxin-II sits on top of the S3-S4 linker in

APA, Harvard, Vancouver, ISO, and other styles

25

Jiang, Hudachuan, Pengfei Jin, Xiling Guo, et al. "The 6-Month Antibody Durability of Heterologous Convidecia Plus CoronaVac and Homologous CoronaVac Immunizations in People Aged 18–59 Years and over 60 Years Based on Two Randomized Controlled Trials in China." Vaccines 11, no. 12 (2023): 1815. http://dx.doi.org/10.3390/vaccines11121815.

Full text

Abstract:

Previous reports have shown that heterologous boosting with the AD5-vectored COVID-19 vaccine Convidecia based on a primary series of two doses of inactivated vaccine induces increasing immune responses. However, the immune persistence until 6 months after the heterologous prime-boost immunization was limited. Participants were from two single-center, randomized, controlled, observer-blinded trials, which involved individuals of 18–59 years of age and over 60 years of age. Eligible participants who previously primed with one dose or two doses of CoronaVac were stratified and randomly assigned

APA, Harvard, Vancouver, ISO, and other styles

26

Kai, Chu, Li Yurong, Liu Shen, et al. "Sustained Immune Persistence Five Years Post-Completion of Four-Dose sIPV Vaccination." Vaccines 13, no. 3 (2025): 253. https://doi.org/10.3390/vaccines13030253.

Full text

Abstract:

Background: The previous study assessed the immune durability of the Sabin strain inactivated poliovirus vaccine (sIPV) at four years of age; an update on its long-term persistence is warranted. Methods: This Phase IV, open-label, parallel-controlled observational study, required by China’s National Medical Products Administration (NMPA), involves 6.5-year-old children who received four doses of sIPV or Salk IPV (wIPV) at 2, 3, 4, and 18 months during the Phase III trial. Participants are recruited in a 2:1 ratio and contribute blood samples for polio-neutralizing antibody (nAb) assays to dete

APA, Harvard, Vancouver, ISO, and other styles

27

Ateudjieu, Jérôme, David A. Sack, Sonia Sonkeng Nafack, et al. "An Age-stratified, Randomized Immunogenicity Trial of Killed Oral Cholera Vaccine with Delayed Second Dose in Cameroon." American Journal of Tropical Medicine and Hygiene 107, no. 5 (2022): 974–83. http://dx.doi.org/10.4269/ajtmh.22-0462.

Full text

Abstract:

ABSTRACT. The recommended schedule for killed oral cholera vaccine (OCV) is two doses, 2 weeks apart. However, during vaccine campaigns, the second round is often delayed by several months. Because more information is needed to document antibody responses when the second dose is delayed, we conducted an open-label, phase 2, noninferiority clinical trial of OCV. One hundred eighty-six participants were randomized into three dose-interval groups (DIGs) to receive the second dose 2 weeks, 6 months, or 11.5 months after the first dose. The DIGs were stratified into three age strata: 1 to 4, 5 to 1

APA, Harvard, Vancouver, ISO, and other styles

28

Han, Jiusheng, Yunhe Cao, Wenhua Wu, et al. "Robust GMTI Scheme for Highly Squinted Hypersonic Vehicle-Borne Multichannel SAR in Dive Mode." Remote Sensing 13, no. 21 (2021): 4431. http://dx.doi.org/10.3390/rs13214431.

Full text

Abstract:

While there are recent researches on hypersonic vehicle-borne multichannel synthetic aperture radar in ground moving target indication (HSV-MC-SAR/GMTI), this article, which specifically explores a robust GMTI scheme for the highly squinted HSV-MC-SAR in dive mode, is novel. First, an improved equivalent range model (IERM) for stationary targets and GMTs is explored, which enjoys a concise expression and therefore offers the potential to simplify the GMTI process. Then, based on the proposed model, a robust GMTI scheme is derived in detail, paying particular attention to Doppler ambiguity aris

APA, Harvard, Vancouver, ISO, and other styles

29

Bahadori, Robab, Majid Reza Ayatollahi, Sergio Cicero, and José Alberto Álvarez. "Geometry Effects on Mode I Brittle Fracture in VO-Notched PMMA Specimens." Polymers 13, no. 17 (2021): 3017. http://dx.doi.org/10.3390/polym13173017.

Full text

Abstract:

This paper gathers experimental and theoretical investigations about both the geometry-dependent fracture initiation angle and the fracture strength in VO-notched polymethyl methacrylate (PMMA) specimens under mode I loading conditions. The numerical analyses revealed that despite the application of pure mode I loading on the geometrically symmetric VO-notched samples, the maximum tangential stress occurs at two points symmetrically placed on either side of the notch bisector line. The experimental tests performed on some specimens showed that a crack does not necessarily propagate along the n

APA, Harvard, Vancouver, ISO, and other styles

30

Jotterand, Veronika, Vinita Jagannath, Andrea Accini Diaz, et al. "A Phase 3 Randomized Trial Investigating the Safety, Tolerability, and Immunogenicity of V116, an Adult-Specific Pneumococcal Vaccine, Compared with PPSV23, in Adults ≥50 Years of Age (STRIDE-10)." Vaccines 13, no. 4 (2025): 341. https://doi.org/10.3390/vaccines13040341.

Full text

Abstract:

Background: V116 is a 21-valent pneumococcal conjugate vaccine (PCV) designed for adults. It contains the most prevalent serotypes associated with invasive pneumococcal disease (IPD) in adults in regions with established pediatric vaccination programs. This Phase 3 study compared the safety, tolerability, and immunogenicity of V116 with 23-valent pneumococcal polysaccharide vaccine (PPSV23) in adults ≥50 years of age. Methods: In this randomized, active comparator-controlled, parallel-group, multisite, double-blind study, participants were randomized 1:1 to receive a single dose of V116 or PPS

APA, Harvard, Vancouver, ISO, and other styles

31

Schwarz, T. F. "An AS04-containing human papillomavirus (HPV) 16/18 vaccine for prevention of cervical cancer is immunogenic and well-tolerated in women 15–55 years old." Journal of Clinical Oncology 24, no. 18_suppl (2006): 1008. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.1008.

Full text

Abstract:

1008 Background: Genital HPV infections can be acquired shortly after sexual debut, and the risk remains throughout a sexually active woman’s lifetime. In women 15–25 years of age, the AS04-containing HPV vaccine was highly immunogenic and conferred 100% protection against HPV-16/18 persistent infection and associated cervical lesions up to 27 months. In the long-term follow-up of this study, sustained vaccine efficacy has been observed up to 48 months. The present phase III study (580299/014) assessed immune responses to the AS04-containing HPV-16/18 vaccine in women 26–55 years old compared

APA, Harvard, Vancouver, ISO, and other styles

32

Findlow, Helen, Samba Sow, Ray Borrow, et al. "Meningococcal Group C and W135 Immunological Hyporesponsiveness in African Toddlers." Clinical and Vaccine Immunology 18, no. 9 (2011): 1492–96. http://dx.doi.org/10.1128/cvi.05020-11.

Full text

Abstract:

ABSTRACTA phase II clinical study was conducted in African toddlers (aged 12 to 23 months), with subjects receiving either investigational meningococcal group A conjugate (PsA-TT), meningococcal ACWY polysaccharide (PsACWY), orHaemophilus influenzaetype b (Hib-TT) vaccine. Ten months following vaccination, the 3 study groups were further randomized to receive a dose of PsA-TT, a 1/5 dose of PsACWY, or a dose of Hib-TT vaccine. Group A serum bactericidal antibody (SBA) results have been reported previously, with PsA-TT demonstrating superior immunogenicity versus PsACWY vaccine. Immunogenicity

APA, Harvard, Vancouver, ISO, and other styles

33

An, Xijie, Yangpeng Zhang, Lili Li, and Qinglin Guo. "Investigation on the Feasibility of Different Semicircular Bend Methods for Asphalt Concrete." Advances in Materials Science and Engineering 2022 (September 23, 2022): 1–10. http://dx.doi.org/10.1155/2022/8403637.

Full text

Abstract:

Cracking of asphalt pavement is mostly caused by the mixed fracture of asphalt concrete. Determining a simple, repeatable, and accurate method is necessary for evaluating the fracture resistance of asphalt concrete. To explore the mixed fracture performance of asphalt concrete and determine the feasibility of different semicircular bend methods, the mixed fracture performances of asphalt concrete at medium and low temperatures were measured. The mixed fracture modes were realized through changing the position of the support and notch or changing the notch angle. After that, the crack propagati

APA, Harvard, Vancouver, ISO, and other styles

34

Weissmueller, Nikolas T., Heiko A. Schiffter, Robert C. Carlisle, Christine S. Rollier, and Andrew J. Pollard. "Needle-Free Dermal Delivery of a Diphtheria Toxin CRM197Mutant on Potassium-Doped Hydroxyapatite Microparticles." Clinical and Vaccine Immunology 22, no. 5 (2015): 586–92. http://dx.doi.org/10.1128/cvi.00121-15.

Full text

Abstract:

ABSTRACTInjections with a hypodermic needle and syringe (HNS) are the current standard of care globally, but the use of needles is not without limitation. While a plethora of needle-free injection devices exist, vaccine reformulation is costly and presents a barrier to their widespread clinical application. To provide a simple, needle-free, and broad-spectrum protein antigen delivery platform, we developed novel potassium-doped hydroxyapatite (K-Hap) microparticles with improved protein loading capabilities that can provide sustained local antigen presentation and release. K-Hap showed increas

APA, Harvard, Vancouver, ISO, and other styles

35

Tang, Xiaoyu, Wen Wan, Zhenxing Lu, and Wei Chen. "Study on Composite Fracture Characteristics and Hydraulic Fracturing Behavior of Hard Rock." Applied Sciences 14, no. 6 (2024): 2585. http://dx.doi.org/10.3390/app14062585.

Full text

Abstract:

To investigate the influence of non-singular terms (T stress) in the stress field on the composite fractures of hard rock Type I–II, such as rock splitting failure and hydraulic fracture propagation, this study focused on hard rocks in metallic mines. Through splitting tests and hydraulic fracturing experiments, the impact of T stress on the characteristics of Type I–II composite fractures in hard rocks was analyzed. Utilizing the generalized maximum tangential (GMTS) stress criterion considering T stress, the stress intensity factors of hard rock Type I–II composite fractures with different p

APA, Harvard, Vancouver, ISO, and other styles

36

Rennels, Margaret B., Steven S. Wasserman, Roger I. Glass, and Virginia A. Keane. "Comparison of Immunogenicity and Efficacy of Rhesus Rotavirus Reassortant Vaccines in Breastfed and Nonbreastfed Children." Pediatrics 96, no. 6 (1995): 1132–36. http://dx.doi.org/10.1542/peds.96.6.1132.

Full text

Abstract:

Objective. To evaluate whether breastfeeding affected the immunogenicity and/or efficacy of candidate rhesus-human rotavirus reassortant vaccines. Methods. A total of 989 healthy infants between 4 and 26 weeks of age were enrolled into a 23-center, prospective, randomized, double-masked, controlled study of the safety, immunogenicity, and efficacy of three doses (4 x 104 plaque-forming units) of monovalent rhesushuman viral protein 7, or G, serotype 1 reassortant vaccine, (RRV-S1) or tetravalent vaccine (RRV-TV) consisting of rhesus-human reassortant G serotypes 1, 2, and 4, and the parent RRV

APA, Harvard, Vancouver, ISO, and other styles

37

MAO, Qun-ying, Xue-yan LIAO, Xiang YU, et al. "Dynamic change of mother-source neutralizing antibodies against enterovirus 71 and coxsackievirus A16 in infants." Chinese Medical Journal 123, no. 13 (2010): 1679–84. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.2010.13.012.

Full text

Abstract:

Background Enterovirus 71 (EV71) and coxsackievirus A16 (Cox A16) are major causative agents for hand, foot and mouth disease (HFMD). Studies indicate that the frequent HFMD outbreaks result in a few hundreds children's death in China in recent years. The vaccine and other research for HFMD need to be developed urgently. The aims of our study were: to explore dynamic development of mother-source neutralizing antibodies against EV71 and Cox A16 in infants from Jiangsu Province, China, and to provide the fundamental data for further establishing of corresponding immunization course. Methods Peri

APA, Harvard, Vancouver, ISO, and other styles

38

Ramgi, Patrícia, Mohamadou Siribie, Njariharinjakamampionona Rakotozandrindrainy, et al. "Immunogenicity and Safety of Heterologous Versus Homologous Prime-Boost Regimens With BBIBP-CorV and Ad26.COV2.S COVID-19 Vaccines: A Multicentric, Randomized, Observer-Blinded Non-inferiority Trial in Madagascar and Mozambique." Clinical Infectious Diseases 80, Supplement_1 (2025): S37—S46. https://doi.org/10.1093/cid/ciaf130.

Full text

Abstract:

Abstract Background Data on immunogenicity and safety of heterologous prime-boost (HePB) regimens using the BBIBP-CorV and Ad26.COV2.S have not yet been reported in sub-Saharan Africa. Methods We conducted a randomized, observer-blinded, non-inferiority trial assessing the immunogenicity and safety of HePB regimens using BBIBP-CorV and Ad26.COV2.S, in adults aged 18–65 years. Participants enrolled, were stratified by baseline severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serostatus, and randomized into four arms in a 1:1:1:1 ratio: A1 (BBIBP-CorV, Ad26.COV2.S), A2 (BBIBP-CorV, B

APA, Harvard, Vancouver, ISO, and other styles

39

Biswal, Shibadas, Jorge Fernando Mendez Galvan, Mercedes Macias Parra, et al. "Immunogenicity and safety of a tetravalent dengue vaccine in dengue-naïve adolescents in Mexico City." Revista Panamericana de Salud Pública 45 (June 11, 2021): 1. http://dx.doi.org/10.26633/rpsp.2021.67.

Full text

Abstract:

Objective. To describe the immunogenicity and safety of a tetravalent dengue vaccine (TAK-003) in healthy adolescents living in Mexico City, an area considered non-endemic for dengue (NCT03341637). Methods. Participants aged 12–17 years were randomized 3:1 to receive two doses (Month 0 and Month 3) of TAK-003 or placebo. Immunogenicity was assessed by microneutralization assay of dengue neutralizing antibodies at baseline, Months 4 and 9. Solicited and unsolicited adverse events (AEs) were recorded after each vaccination. Serious (SAEs) and medically-attended AEs (MAAEs) were recorded througho

APA, Harvard, Vancouver, ISO, and other styles

40

Kim, Yunhwa, Ji-Young Hwang, Kyung-Min Lee, Eunsil Lee, and Hosun Park. "Cross-Sectional Study of Varicella Zoster Virus Immunity in Healthy Korean Children Assessed by Glycoprotein Enzyme-Linked Immunosorbent Assay and Fluorescent Antibody to Membrane Antigen Test." Vaccines 9, no. 5 (2021): 492. http://dx.doi.org/10.3390/vaccines9050492.

Full text

Abstract:

The prevalence of varicella is especially high among children in the age group of 4–6 years in South Korea, regardless of vaccination. We investigated the immune status of healthy children enrolled in day-care centers and compared pre- and post-vaccination immunity. Antibody titers were measured using a glycoprotein enzyme-linked immunosorbent assay (gpEIA) kit, and the seroconversion rate was assessed using a fluorescent antibody to membrane antigen (FAMA) test. Among 541 vaccinated children, 109 (20.1%) had breakthrough varicella. However, 13 (72.2%) of the 18 unvaccinated children had a his

APA, Harvard, Vancouver, ISO, and other styles

41

Wakeman, M. D., P. O. Hagstrand, F. Bonjour, P. E. Bourban, and J. A. E. Månson. "Robotic tow placement for local reinforcement of glass mat thermoplastics (GMTs)." Composites Part A: Applied Science and Manufacturing 33, no. 9 (2002): 1199–208. http://dx.doi.org/10.1016/s1359-835x(02)00086-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Sharifi, N., C. Ma, C. Seow, et al. "A195 DURABILITY OF SEROLOGICAL RESPONSES AFTER SECOND, THIRD AND FOURTH DOSE OF SARS-COV-2 VACCINATION IN INFLAMMATORY BOWEL DISEASE: A PROSPECTIVE COHORT STUDY." Journal of the Canadian Association of Gastroenterology 6, Supplement_1 (2023): 39. http://dx.doi.org/10.1093/jcag/gwac036.195.

Full text

Abstract:

Abstract Background Adequate serological responses following two-dose regimens and additional doses of SARS-CoV-2 vaccination have been demonstrated for the vast majority of those with IBD. However, antibody levels following 2nd, 3rd, and 4th dose SARS-CoV-2 vaccination may decrease over time in the IBD population. Purpose We assessed the durability of serological responses to 2nd, 3rd, and 4th dose SARS-CoV-2 vaccination over time in a cohort of IBD patients. Method Adults with IBD who received at least one dose of a SARS-CoV-2 vaccine (n=559) were evaluated for serological response to the sp

APA, Harvard, Vancouver, ISO, and other styles

43

Christy, Cynthia, Michael E. Pichichero, George F. Reed, et al. "Effect of Gender, Race, and Parental Education on Immunogenicity and Reported Reactogenicity of Acellular and Whole-Cell Pertussis Vaccines." Pediatrics 96, no. 3 (1995): 584–87. http://dx.doi.org/10.1542/peds.96.3.584.

Full text

Abstract:

Objective. To determine whether gender, race (black or white), or level of parental education influenced serologic responses or reporting of clinical reactions after immunization with acellular (DTaP) or whole-cell (DTP) pertussis vaccine with diphtheria and tetanus toxoids combined. Methods. Healthy infants were prospectively randomized to receive one of 13 DTaP, Lederle DTP, or another DTP. Parents recorded the occurrence of adverse reactions for 2 weeks after each inoculation. Sera obtained before the first immunization and 1 month after the third immunization were analyzed for antibody to

APA, Harvard, Vancouver, ISO, and other styles

44

Chang, Dong-Shang, and Wei-De Wu. "Impact of the COVID-19 Pandemic on the Tourism Industry: Applying TRIZ and DEMATEL to Construct a Decision-Making Model." Sustainability 13, no. 14 (2021): 7610. http://dx.doi.org/10.3390/su13147610.

Full text

Abstract:

The impact of the COVID-19 pandemic on the tourism industry is still being sustained, and the response of the tourism industry is an indispensable element that is increasingly recognized. This response has led to the emergence of literature about the impact of COVID-19 on the stakeholders of the tourism industry, thereby contributing to the industry. Nonetheless, the criteria factors and investigated practices for the implementation of decision-making by stakeholders in the tourism industry have not been fully explored. This study adopts Teorija Rezhenija Izobre-tatelskikh Zadach (TRIZ) princi

APA, Harvard, Vancouver, ISO, and other styles

45

Quiambao, Beatriz, Paula Peyrani, Chris Webber, et al. "1478. Efficacy and Safety of a Booster Dose of the MenACWY-TT Vaccine Administered 10 Years After Primary Vaccination with MenACWY-TT or MenACWY-PS." Open Forum Infectious Diseases 6, Supplement_2 (2019): S539. http://dx.doi.org/10.1093/ofid/ofz360.1342.

Full text

Abstract:

Abstract Background The quadrivalent meningococcal ACWY polysaccharide tetanus toxoid conjugate vaccine (MenACWY-TT; Nimenrix) is licensed in various countries to prevent disease caused by meningococcal serogroups A, C, W, and Y. In a previous study (NCT00464815), subjects aged 11‒17 years received a primary dose of MenACWY-TT or a quadrivalent polysaccharide vaccine (MenACWY-PS). Here, we report the long-term antibody persistence of the primary dose and the immunogenicity and safety of a booster dose given 10 years after primary vaccination of subjects. Methods Participants were enrolled from

APA, Harvard, Vancouver, ISO, and other styles

46

Hedrick, James, Michael W. Simon, Shane Christensen, et al. "2725. Immunogenicity and Safety of a Booster Dose of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW-TT) in Adolescents and Adults." Open Forum Infectious Diseases 6, Supplement_2 (2019): S959. http://dx.doi.org/10.1093/ofid/ofz360.2402.

Full text

Abstract:

Abstract Background The MenACYW-TT conjugate vaccine is a quadrivalent meningococcal vaccine that contains tetanus toxoid as carrier protein. Vaccine is intended for global use in all age groups (i.e., individuals 6 weeks of age and older). This Phase III study evaluated the safety and immunogenicity of the vaccine when compared with a licensed quadrivalent meningococcal conjugate vaccine in individuals ≥ 15 years of age. Methods A randomized, modified double-blind study (NCT02752906) was conducted in the United States and Puerto Rico. The study evaluated 810 participants primed with a license

APA, Harvard, Vancouver, ISO, and other styles

47

Quiambao, Beatriz, Paula Peyrani, Chris Webber, et al. "2722 B. Efficacy and Safety of a Booster Dose of the MenACWY-TT Vaccine Administered 10 Years After Primary Vaccination with MenACWY-TT or MenACWY-PS." Open Forum Infectious Diseases 6, Supplement_2 (2019): S960—S961. http://dx.doi.org/10.1093/ofid/ofz360.2406.

Full text

Abstract:

Abstract Background The quadrivalent meningococcal ACWY polysaccharide tetanus toxoid conjugate vaccine (MenACWY-TT; Nimenrix) is licensed in various countries to prevent disease caused by meningococcal serogroups A, C, W, and Y. In a previous study (NCT00464815), subjects aged 11‒17 years received a primary dose of MenACWY-TT or a quadrivalent polysaccharide vaccine (MenACWY-PS). Here, we report the long-term antibody persistence of the primary dose and the immunogenicity and safety of a booster dose given 10 years after primary vaccination of subjects. Methods Participants were enrolled from

APA, Harvard, Vancouver, ISO, and other styles

48

Tricou, Vianney, Brandon Essink, John E. Ervin, et al. "Immunogenicity and safety of concomitant and sequential administration of yellow fever YF-17D vaccine and tetravalent dengue vaccine candidate TAK-003: A phase 3 randomized, controlled study." PLOS Neglected Tropical Diseases 17, no. 3 (2023): e0011124. http://dx.doi.org/10.1371/journal.pntd.0011124.

Full text

Abstract:

Background Yellow fever (YF) vaccination is often mandatory for travelers to YF-endemic areas. The areas with risk of YF partially overlap with those of dengue, for which there is currently no recommended vaccine available for dengue-naïve individuals. This phase 3 study assessed the immunogenicity and safety of concomitant and sequential administration of YF (YF-17D) and tetravalent dengue (TAK-003) vaccines in healthy adults aged 18–60 years living in areas of the US non-endemic for either virus. Methods Participants were randomized 1:1:1 to receive the following vaccinations at Months 0, 3,

APA, Harvard, Vancouver, ISO, and other styles

49

Halperin, Scott A., Rituparna Das, Matthew T. Onorato та ін. "Immunogenicity, Lot Consistency, and Extended Safety of rVSVΔG-ZEBOV-GP Vaccine: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study in Healthy Adults". Journal of Infectious Diseases 220, № 7 (2019): 1127–35. http://dx.doi.org/10.1093/infdis/jiz241.

Full text

Abstract:

Abstract Background This double-blind study assessed immunogenicity, lot consistency, and safety of recombinant vesicular stomatitis virus-Zaire Ebola virus envelope glycoprotein vaccine (rVSVΔG-ZEBOV-GP). Methods Healthy adults (N = 1197) were randomized 2:2:2:2:1 to receive 1 of 3 consistency lots of rVSVΔG-ZEBOV-GP (2 × 107 plaque-forming units [pfu]), high-dose 1 × 108 pfu, or placebo. Antibody responses pre-/postvaccination (28 days, 6 months; in a subset [n = 566], months 12, 18, and 24) were measured. post hoc analysis of risk factors associated with arthritis following vaccination was

APA, Harvard, Vancouver, ISO, and other styles

50

Chirkova, T. V., A. N. Naykhin, G. D. Petukhova, et al. "Memory T-Cell Immune Response in Healthy Young Adults Vaccinated with Live Attenuated Influenza A (H5N2) Vaccine." Clinical and Vaccine Immunology 18, no. 10 (2011): 1710–18. http://dx.doi.org/10.1128/cvi.05116-11.

Full text

Abstract:

ABSTRACTCellular immune responses of both CD4 and CD8 memory/effector T cells were evaluated in healthy young adults who received two doses of live attenuated influenza A (H5N2) vaccine. The vaccine was developed by reassortment of nonpathogenic avian A/Duck/Potsdam/1402-6/68 (H5N2) and cold-adapted A/Leningrad/134/17/57 (H2N2) viruses. T-cell responses were measured by standard methods of intracellular cytokine staining of gamma interferon (IFN-γ)-producing cells and a novel T-cell recognition of antigen-presenting cells by protein capture (TRAP) assay based on the trogocytosis phenomenon, na

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!