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1

Putri, Rika Diananing, and Imam Hanafi. "FORMULASI GARAM DAN MADU TERHADAP KARAKTERISTIK MASKER WAJAH." Journal of Food Technology and Agroindustry 4, no. 1 (2022): 26–31. http://dx.doi.org/10.24929/jfta.v4i1.1854.

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Salt is a natural product made from evaporation of sea water with the help of sunlight. The benefits of salt are many, both for food, health, and beauty needs. In addition, salt can treat skin diseases, overcome rough skin. Honey has good benefits for the health of the body, both externally and internally. The purpose of this study was to compile the ingredient formula and determine the effect of the raw material formula on the physical and organoleptic properties of facial mask products made from salt and honey. The use of salt into beauty products (masks for the face) by formulating salt and
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Yaghoubi Khanghahi, Mohammad, Maddalena Curci, Eugenio Cazzato, et al. "Shifts in Soil Bacterial Communities under Three-Year Fertilization Management and Multiple Cropping Systems." Soil Systems 8, no. 1 (2024): 5. http://dx.doi.org/10.3390/soilsystems8010005.

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The current study was undertaken to investigate how organic and inorganic fertilizers shape soil bacterial communities and soil nitrogen and carbon status and to find their relationships with plant production. Soils were collected from fields under a three-year application of green manures (vetch (GMV), field bean (GMB), and wheat (GMW)), livestock manure (MF), inorganic mineral fertilizer (IF), and control (no nitrogen fertilization). The plants cultivated during the three years were tomato, watermelon, and pepper, respectively. The findings showed an increase in crop yields under both organi
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Kobe, Elizabeth, Cynthia J. Coffman, Amy S. Jeffreys, et al. "4063 Glycemic control in a weight management-focused group medical visits (WM/GMV) intervention: examining the moderating effects of body mass index (BMI)." Journal of Clinical and Translational Science 4, s1 (2020): 31. http://dx.doi.org/10.1017/cts.2020.130.

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OBJECTIVES/GOALS: The impact of baseline BMI on glycemic response to group medical visits (GMV) and weight management (WM)-based interventions is unclear. Our objective is to determine how baseline BMI class impacts patient responses to GMV and interventions that combine WM/GMV. METHODS/STUDY POPULATION: We will perform a secondary analysis of Jump Start, a randomized, controlled trial that compared the effectiveness of a GMV-based low carbohydrate diet-focused WM program (WM/GMV) to traditional GMV-based medication management (GMV) on diabetes control. The primary and secondary outcomes will
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Bullens, Kristien, Jeroen Blommaert, Charlotte SLeurs, Jurgen Lemiere, and Sandra Jacobs. "IMG-17. CHANGES IN GRAY MATTER VOLUMES AND THEIR RELATION WITH NEUROPSYCHOLOGICAL DOMAIN SCORES IN SURVIVORS OF A CHILDHOOD POSTERIOR FOSSA TUMOR." Neuro-Oncology 26, Supplement_4 (2024): 0. http://dx.doi.org/10.1093/neuonc/noae064.354.

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Abstract Posterior fossa tumors (PFT) often need neurotoxic radiotherapy (RT). These may affect the brain and contribute to neurocognitive impairment later in life. Therefore, we investigated region-based gray matter volumes (GMV) and their relation to neurocognitive functioning (NF) in PFT survivors. T1-weighted MRI (MPRAGE, resolution=.98x.98x1.2mm) and NF composite scores based on a compressive neuropsychological test battery: total Intelligence, verbal comprehension, working memory, perceptual reasoning, processing speed, language, learning and memory, complex attention (CA), and cognitive
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Redel, Jacob M., Mark DiFrancesco, Jennifer Vannest, et al. "Brain gray matter volume differences in obese youth with type 2 diabetes: a pilot study." Journal of Pediatric Endocrinology and Metabolism 31, no. 3 (2018): 261–68. http://dx.doi.org/10.1515/jpem-2017-0349.

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AbstractBackground:Adults with type 2 diabetes (T2D) have significantly lower gray matter volume (GMV) compared to healthy peers. Whether GMV differences exist in youth with T2D remains unclear. Thus, we compared global and regional GMV between obese youth with T2D with age, race and sex similar healthy controls.Methods:In a cross-sectional study, 20 obese youth with T2D underwent T1-weighted brain magnetic resonance imaging (MRI). Comparisons were made to 20 age, race and sex similar controls. Differences in global and regional GMV between groups were identified using voxel-based morphometry
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Strickland, Carmen, Joanne C. Sandberg, Stephen W. Davis, and Sally P. Weaver. "Group Medical Visit Training in Family Medicine Residency:." Family Medicine 51, no. 4 (2019): 319–25. http://dx.doi.org/10.22454/fammed.2019.316336.

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Background and Objectives: Group medical visits (GMV) have been shown to improve clinical outcomes and patient satisfaction and are included as a new tool in the patient-centered medical home (PCMH). The capacity for and interest in developing GMV skills in family medicine residency have not been assessed. This study aims to describe the extent of existing training in GMV as well as attitudes toward and barriers to this training. Methods: The Council of Academic Family Medicine Educational Research Alliance (CERA) sent a survey in the fall of 2015 to all US family medicine residency program di
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Migueles, Jairo H., Cristina Cadenas-Sanchez, Irene Esteban-Cornejo, et al. "Associations of Objectively-Assessed Physical Activity and Sedentary Time with Hippocampal Gray Matter Volume in Children with Overweight/Obesity." Journal of Clinical Medicine 9, no. 4 (2020): 1080. http://dx.doi.org/10.3390/jcm9041080.

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This study investigated physical activity (PA) and sedentary time (SED) in relation to hippocampal gray matter volume (GMV) in pediatric overweight/obesity. Ninety-three children (10 ± 1 year) were classified as overweight, obesity type I, or type II–III. PA was assessed with non-dominant wrist accelerometers. GMV was acquired by magnetic resonance imaging (MRI). Neither PA nor SED associated with GMV in the hippocampus in the whole sample (p > 0.05). However, we found some evidence of moderation by weight status (p < 0.150). Moderate-to-vigorous PA (MVPA) positively associated with GMV
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Liu, Yuexin, Lina Zhu, Kelong Cai, et al. "Relationship between Cardiorespiratory Fitness and Executive Function in Young Adults: Mediating Effects of Gray Matter Volume." Brain Sciences 12, no. 11 (2022): 1441. http://dx.doi.org/10.3390/brainsci12111441.

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We evaluated the association between cardiorespiratory fitness (CRF) and executive function (EF) in young adults and the mediating effects of GMV on this relationship. This study involved 217 college students. An incremental load exercise program was used to evaluate VO2max. EF was estimated by the Flanker task, the 2-back task, and the more-odd shifting task, while structural magnetic resonance and region-based morphometry (RBM) were used to analyze GMV. The high CRF group had a shorter updating reaction time (RT) (p ≤ 0.05). CRF was positively correlated with the right orbital part of the mi
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Mugikura, Shunji, Naoko Mori, Miyeong Gang, et al. "Interhemispheric asymmetrical change in gray matter volume in patients with unilateral hippocampal sclerosis." Journal of Clinical Imaging Science 13 (December 22, 2023): 38. http://dx.doi.org/10.25259/jcis_77_2023.

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Objectives: To clarify the interhemispheric asymmetrical change in gray matter volume (GMV) in unilateral hippocampal sclerosis (HS), we compared changes in GMV relative to normal subjects between the HS and contralateral or non-HS sides. Material and Methods: Forty-five patients with unilateral HS and 30 healthy subjects were enrolled. We quantified changes in GMV in the patients with HS as compared to GMV in the normal subjects by introducing the Z-score (Z-GMV) in each region or region of interest in unilateral HS. Then, we assessed the asymmetrically decreased regions, that is, regions wit
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Modinos, Gemma, Alice Egerton, Anna McLaughlin, et al. "Neuroanatomical changes in people with high schizotypy: relationship to glutamate levels." Psychological Medicine 48, no. 11 (2017): 1880–89. http://dx.doi.org/10.1017/s0033291717003403.

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BackgroundCortical glutamatergic dysfunction is thought to be fundamental for psychosis development, and may lead to structural degeneration through excitotoxicity. Glutamate levels have been related to gray matter volume (GMV) alterations in people at ultra-high risk of psychosis, and we previously reported GMV changes in individuals with high schizotypy (HS), which refers to the expression of schizophrenia-like characteristics in healthy people. This study sought to examine whether GMV changes in HS subjects are related to glutamate levels.MethodsWe selected 22 healthy subjects with HS and 2
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Kobe, Elizabeth A., Mathew J. Crowley, Amy Jeffreys, et al. "44499 Heterogeneity of treatment effect among patients with type 2 diabetes and body mass index >=27kg/m^2 in the Jump Start Study." Journal of Clinical and Translational Science 5, s1 (2021): 47. http://dx.doi.org/10.1017/cts.2021.525.

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ABSTRACT IMPACT: This is the first study to use QUINT analyses to examine heterogeneity of treatment effect for group medical visits among individuals with type 2 diabetes. QUINT is a data driven method that assumes no a priori assumptions regarding effect moderators - an important step in the path towards personalized medicine. OBJECTIVES/GOALS: To examine heterogeneity of treatment effect (HTE) in Jump Start, a trial that compared the effectiveness of group medical visits (GMVs) focused on medication management only versus the addition of intensive weight management (WM) on glycemic control
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Lai, Tzu-Hsien, Kung-Hsien Chou, Jong-Ling Fuh, et al. "Gray matter changes related to medication overuse in patients with chronic migraine." Cephalalgia 36, no. 14 (2016): 1324–33. http://dx.doi.org/10.1177/0333102416630593.

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Objective The objective of this article is to investigate the neurological substrates associated with medication overuse (MO) in patients with chronic migraine (CM). Methods We recruited age- and sex-matched CM patients with MO (CMwMO), CM patients without MO (CMwoMO), and healthy controls (HCs). Magnetic resonance T1-weighted images were processed by voxel-based morphometry, and the findings were correlated with clinical variables and treatment responses. Results A total of 66 patients with CM (half with MO) and 33 HCs completed the study. Patients with CMwMO compared to the patients with CMw
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Schug, Alison K., Edith Brignoni-Perez, Nasheed Jamal, and Guinevere F. Eden. "11791 Gray matter volume differences in bilingual compared to monolingual children." Journal of Clinical and Translational Science 5, s1 (2021): 20–21. http://dx.doi.org/10.1017/cts.2021.457.

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ABSTRACT IMPACT: This study examines gray matter volume differences resulting from the bilingual experience in children and adults allowing us to better understand the brains of over half of the world’s population that speaks more than one language. OBJECTIVES/GOALS: Literature is mixed regarding a bilingual advantage in executive control (EC). While it has been shown that young adult bilinguals have greater gray matter volume (GMV) than monolinguals in EC regions, there is behavioral evidence that suggests such difference would be more pronounced in children. METHODS/STUDY POPULATION: Using S
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Solomons, Daniel, Maria Rodriguez-Fernandez, Francisco Mery-Muñoz, Leonardo Arraño-Carrasco, Francisco Sahli Costabal, and Carolina Mendez-Orellana. "Assessing Language Lateralization through Gray Matter Volume: Implications for Preoperative Planning in Brain Tumor Surgery." Brain Sciences 14, no. 10 (2024): 954. http://dx.doi.org/10.3390/brainsci14100954.

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Background/Objectives: Functional MRI (fMRI) is widely used to assess language lateralization, but its application in patients with brain tumors can be hindered by cognitive impairments, compensatory neuroplasticity, and artifacts due to patient movement or severe aphasia. Gray matter volume (GMV) analysis via voxel-based morphometry (VBM) in language-related brain regions may offer a stable complementary approach. This study investigates the relationship between GMV and fMRI-derived language lateralization in healthy individuals and patients with left-hemisphere brain tumors, aiming to enhanc
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Han, Pengfei, Martina Musch, Nasreddin Abolmaali, and Thomas Hummel. "Improved Odor Identification Ability and Increased Regional Gray Matter Volume After Olfactory Training in Patients With Idiopathic Olfactory Loss." i-Perception 12, no. 2 (2021): 204166952110058. http://dx.doi.org/10.1177/20416695211005811.

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Idiopathic olfactory loss (IOL) is thought as an early marker for neurodegenerative disease. This study investigated the effect of olfactory training (OT) on regional gray matter volume (GMV) among patients with IOL. A total of 24 patients (mean age 64.6 years, 11 male) with IOL and 30 control participants with normal olfaction (mean age 62.6 years, 13 males) were included in the study. Voxel-based morphometry was performed to compare the GMV between patient and control groups. Only the patients received OT (averaged duration 7 months), and a longitudinal approach was used to examine the GMV c
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Zou, Liwei, Xiaoyan Wu, Shuman Tao, et al. "Anterior cingulate gyrus acts as a moderator of the relationship between problematic mobile phone use and depressive symptoms in college students." Social Cognitive and Affective Neuroscience 16, no. 5 (2021): 484–91. http://dx.doi.org/10.1093/scan/nsab016.

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Abstract This study aimed to investigate the brain grey matter volume (GMV) related to problematic mobile phone use (PMPU), and whether these regions of GMV play a potential moderating role in the relationship between PMPU and depressive symptoms. We recruited 266 students who underwent magnetic resonance imaging (MRI) scanning. PMPU and depressive symptoms were assessed by a self-rating questionnaire for adolescent PMPU and patient health questionnaire-9, respectively. A multiple regression model was performed to detect GMV and white matter (WM) integrity associated with PMPU by voxel-based m
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Choi, Hyon-Il, Kiyoon Kim, Jiyoon Lee, et al. "Relationship between Brain Tissue Changes and Blood Biomarkers of Cyclophilin A, Heme Oxygenase-1, and Inositol-Requiring Enzyme 1 in Patients with Alzheimer’s Disease." Diagnostics 11, no. 5 (2021): 740. http://dx.doi.org/10.3390/diagnostics11050740.

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Cyclophilin A (CypA), heme oxygenase-1 (HO-1), and inositol-requiring enzyme 1 (IRE1) are believed to be associated with Alzheimer’s disease (AD). In this study, we investigated the association between gray matter volume (GMV) changes and blood levels of CypA, HO-1, and IRE1 in cognitively normal (CN) subjects and those with amnestic mild cognitive impairment (aMCI) and AD. Forty-five elderly CN, 34 aMCI, and 39 AD subjects were enrolled in this study. The results of voxel-based multiple regression analysis showed that blood levels of CypA, HO-1, and IRE1 were correlated with GMV on brain magn
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Rachůnek, Jiří, and Dana Šalounová. "Monadic GMV-algebras." Archive for Mathematical Logic 47, no. 3 (2008): 277–97. http://dx.doi.org/10.1007/s00153-008-0086-2.

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Nola, A. Di, A. Dvurečenskij, and C. Tsinakis. "Perfect GMV-Algebras." Communications in Algebra 36, no. 4 (2008): 1221–49. http://dx.doi.org/10.1080/00927870701862852.

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Hernández, Sergio Elías, Roberto Dorta, José Suero, Alfonso Barros-Loscertales, José Luis González-Mora, and Katya Rubia. "Larger whole brain grey matter associated with long-term Sahaja Yoga Meditation: A detailed area by area comparison." PLOS ONE 15, no. 12 (2020): e0237552. http://dx.doi.org/10.1371/journal.pone.0237552.

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Objectives Our previous study showed that long-term practitioners of Sahaja Yoga Meditation (SYM) had around 7% larger grey matter volume (GMV) in the whole brain compared with healthy controls; however, when testing individual regions, only 5 small brain areas were statistically different between groups. Under the hypothesis that those results were statistically conservative, with the same dataset, we investigated in more detail the regional differences in GMV associated with the practice of SYM, with a different statistical approach. Design Twenty-three experienced practitioners of SYM and 2
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Jiang, Aili, Jing Tian, Rui Li, et al. "Alterations of Regional Spontaneous Brain Activity and Gray Matter Volume in the Blind." Neural Plasticity 2015 (2015): 1–12. http://dx.doi.org/10.1155/2015/141950.

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Visual deprivation can induce alterations of regional spontaneous brain activity (RSBA). However, the effects of onset age of blindness on the RSBA and the association between the alterations of RSBA and brain structure are still unclear in the blind. In this study, we performed resting-state functional and structural magnetic resonance imaging on 50 sighted controls and 91 blind subjects (20 congenitally blind, 27 early blind, and 44 late blind individuals). Compared with the sighted control, we identified increased RSBA in the blind in primary and high-level visual areas and decreased RSBA i
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Švrček, Filip. "Operators on $GMV$-algebras." Mathematica Bohemica 129, no. 4 (2004): 337–47. http://dx.doi.org/10.21136/mb.2004.134044.

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Song, Hyehyun, Myong-Wuk Chon, Vin Ryu, et al. "Cortical Volumetric Correlates of Childhood Trauma, Anxiety, and Impulsivity in Bipolar Disorder." Psychiatry Investigation 17, no. 7 (2020): 627–35. http://dx.doi.org/10.30773/pi.2019.0305.

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Objective More recently, attention has turned to the linkage between childhood trauma and emotional dysregulation, but the evidence in bipolar disorder (BD) is limited. To determine neurobiological relationships between childhood trauma, current anxiety, and impulsivity, we investigated cortical volumetric correlates of these clinical factors in BD.Methods We studied 36 patients with DSM-5 BD and 29 healthy controls. Childhood trauma, coexisting anxiety, and impulsivity were evaluated with the Korean version-Childhood Trauma Questionnaire (CTQ), the Korean version-Beck Anxiety Inventory (BAI),
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Trejo, Evelin, Ana I. Velazquez, Elizabeth Castillo, et al. "Abstract P4-11-19: Utilization of the RE-AIM frameworkfor evaluating the implementation of group medical visit for low-income breast cancer survivors." Cancer Research 82, no. 4_Supplement (2022): P4–11–19—P4–11–19. http://dx.doi.org/10.1158/1538-7445.sabcs21-p4-11-19.

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Abstract Introduction: Providing cost effective comprehensive survivorship care (SC) remains a major challenge for which optimal delivery models are needed. Group medical visits (GMV) are commonly used in chronic diseases to deliver medical care, education, and empower patients. Pilot GMV studies for breast cancer survivors (BCS) have shown increases in peer support and patient education. This pilot study uses the RE-AIM framework for evaluation of the GMV intervention to support breast cancer survivors. RE-AIM is an efficient framework for systematic evaluation of health care interventions. R
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Coppieters, Iris. "Decreased Regional Grey Matter Volume in Women with Chronic Whiplash-Associated Disorders: Relationships with Cognitive Deficits and Disturbed Pain Processing." Pain Physician 7, no. 20;7 (2017): E1025—E1051. http://dx.doi.org/10.36076/ppj/2017.7.e1025.

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Background: Patients with chronic whiplash-associated disorders (CWAD) are characterized by pain of traumatic origin, cognitive deficits, and central sensitization (CS). Previous neuroimaging studies revealed altered grey matter volume (GMV) in mild traumatic brain injury patients and chronic pain conditions also characterized by CS. It can therefore be hypothesized that GMV alterations also play a role in the persistent complaints of CWAD. However, brain alterations remain poorly investigated in these patients. Objectives: This study examined regional GMV alterations in patients with CWAD com
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Algotar, Amit, Stephanie Trofymenko, Myra Muramoto, Amy Howerter, and Randa Kutob. "Group Medical Visits for Addressing Weight and Blood Pressure in an Underserved Population." Medicines 9, no. 12 (2022): 60. http://dx.doi.org/10.3390/medicines9120060.

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The effect of group medical visits (GMV) compared to individual medical visits (IMV), on weight and blood pressure in a large primary care practice serving a predominantly underserved population, was assessed. The records of 304 patients attending a weight-loss program were analyzed using mixed-effects regression models. Patients in GMV lost an average of 11.63 lbs, whereas patients in IMV lost an average of 3.99 lbs (p < 0.001). A total of 55% of patients lost ≥7% in GMV compared to 11% of patients in IMV (p ≤ 0.001). Individuals who lost >5% of their baseline weight had a higher reduct
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Lee, Sungeun Melanie, Michaela M. Milillo, Beatrix Krause-Sorio, et al. "Gut Microbiome Diversity and Abundance Correlate with Gray Matter Volume (GMV) in Older Adults with Depression." International Journal of Environmental Research and Public Health 19, no. 4 (2022): 2405. http://dx.doi.org/10.3390/ijerph19042405.

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Growing evidence supports the concept that bidirectional brain–gut microbiome interactions play an important mechanistic role in aging, as well as in various neuropsychiatric conditions including depression. Gray matter volume (GMV) deficits in limbic regions are widely observed in geriatric depression (GD). We therefore aimed to explore correlations between gut microbial measures and GMV within these regions in GD. Sixteen older adults (>60 years) with GD (37.5% female; mean age, 70.6 (SD = 5.7) years) were included in the study and underwent high-resolution T1-weighted structural MRI scan
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Froeliger, Brett, Eric L. Garland, and F. Joseph McClernon. "Yoga Meditation Practitioners Exhibit Greater Gray Matter Volume and Fewer Reported Cognitive Failures: Results of a Preliminary Voxel-Based Morphometric Analysis." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/821307.

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Hatha yoga techniques, including physical postures (asanas), breathing exercises (pranayama), and meditation, involve the practice of mindfulness. In turn, yoga meditation practices may induce the state of mindfulness, which, when evoked recurrently through repeated practice, may accrue into trait or dispositional mindfulness. Putatively, these changes may be mediated by experience-dependent neuroplastic changes. Though prior studies have identified differences in gray matter volume (GMV) between long-term mindfulness practitioners and controls, no studies to date have reported on whether yoga
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Chen, Z., W. Deng, Q. Gong, et al. "Extensive brain structural network abnormality in first-episode treatment-naive patients with schizophrenia: morphometrical and covariation study." Psychological Medicine 44, no. 12 (2014): 2489–501. http://dx.doi.org/10.1017/s003329171300319x.

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BackgroundAlterations in gray matter (GM) are commonly observed in schizophrenia. Accumulating studies suggest that the brain changes associated with schizophrenia are distributed rather than focal, involving interconnected networks of areas as opposed to single regions. In the current study we aimed to explore GM volume (GMV) changes in a relatively large sample of treatment-naive first-episode schizophrenia (FES) patients using optimized voxel-based morphometry (VBM) and covariation analysis.MethodHigh-resolution T1-weighted images were obtained using 3.0-T magnetic resonance imaging (MRI) f
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Cheng, Wei, Zhiyuan Sun, Kelong Cai, et al. "Relationship between Overweight/Obesity and Social Communication in Autism Spectrum Disorder Children: Mediating Effect of Gray Matter Volume." Brain Sciences 13, no. 2 (2023): 180. http://dx.doi.org/10.3390/brainsci13020180.

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With advances in medical diagnostic technology, the healthy development of children with autism spectrum disorder (ASD) is receiving more and more attention. In this article, the mediating effect of brain gray matter volume (GMV) between overweight/obesity and social communication (SC) was investigated through the analysis of the relationship between overweight/obesity and SC in autism spectrum disorder children. In total, 101 children with ASD aged 3–12 years were recruited from three special educational centers (Yangzhou, China). Overweight/obesity in children with ASD was indicated by their
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Kim, JH, S.-I. Suh, HY Seol, et al. "Regional Grey Matter Changes in Patients With Migraine: A Voxel-Based Morphometry Study." Cephalalgia 28, no. 6 (2008): 598–604. http://dx.doi.org/10.1111/j.1468-2982.2008.01550.x.

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We used voxel-based morphometry (VBM) to compare grey matter volume (GMV) between 20 migraine patients (five with aura and 15 without aura) with normal conventional magnetic resonance imaging findings and 33 healthy controls matched for age and sex. A separate analysis was also performed to delineate a possible correlation between the GMV changes and the headache duration or lifetime headache frequency. When compared with controls, migraine patients had significant GMV reductions in the bilateral insula, motor/premotor, prefrontal, cingulate cortex, right posterior parietal cortex, and orbitof
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Yang, Young-Min, Soon-Il An, Bin Wang, and Jae Heung Park. "A global-scale multidecadal variability driven by Atlantic multidecadal oscillation." National Science Review 7, no. 7 (2019): 1190–97. http://dx.doi.org/10.1093/nsr/nwz216.

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ABSTRACT Observational analysis shows that there is a predominant global-scale multidecadal variability (GMV) of sea-surface temperature (SST). Its horizontal pattern resembles that of the interdecadal Pacific oscillation (IPO) in the Pacific and the Atlantic multidecadal oscillation (AMO) in the Atlantic Ocean, which could affect global precipitation and temperature over the globe. Here, we demonstrate that the GMV could be driven by the AMO through atmospheric teleconnections and atmosphere–ocean coupling processes. Observations reveal a strong negative correlation when AMO leads GMV by appr
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Piervincenzi, Claudia, Martina Fanella, Nikolaos Petsas, et al. "Structural Cerebellar Abnormalities and Parkinsonism in Patients with 22q11.2 Deletion Syndrome." Brain Sciences 12, no. 11 (2022): 1533. http://dx.doi.org/10.3390/brainsci12111533.

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Background: The phenotypic expression of 22q11.2 deletion syndrome (22q11.2DS) is variable and may include cognitive, psychiatric, and neurological manifestations, e.g., parkinsonism. We investigated brain structural alterations in patients with 22q11.2DS with and without parkinsonism (Park+ and Park−) in comparison with healthy controls (HCs). Methods: Voxel-based morphometry was performed on 3D T1-weighted MR images to explore gray matter volume (GMV) differences between 29 patients (15 Park+, 14 Park−), selected from a consecutive series of 56 adults diagnosed with 22q11.2DS, and 24 HCs. On
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Liu, Siyuan, Jakob Seidlitz, Jonathan D. Blumenthal, Liv S. Clasen, and Armin Raznahan. "Integrative structural, functional, and transcriptomic analyses of sex-biased brain organization in humans." Proceedings of the National Academy of Sciences 117, no. 31 (2020): 18788–98. http://dx.doi.org/10.1073/pnas.1919091117.

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Humans display reproducible sex differences in cognition and behavior, which may partly reflect intrinsic sex differences in regional brain organization. However, the consistency, causes and consequences of sex differences in the human brain are poorly characterized and hotly debated. In contrast, recent studies in mice—a major model organism for studying neurobiological sex differences—have established: 1) highly consistent sex biases in regional gray matter volume (GMV) involving the cortex and classical subcortical foci, 2) a preponderance of regional GMV sex differences in brain circuits f
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Halsey, Lewis G., Gabriel P. Esteves, and Eimear Dolan. "Variability in variability: does variation in morphological and physiological traits differ between men and women?" Royal Society Open Science 10, no. 9 (2023). http://dx.doi.org/10.1098/rsos.230713.

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Many researchers presume greater variability between female participants than between males due to the menstrual cycle. This view has encouraged a sex bias in health and medical research, resulting in considerable knowledge gaps with important clinical implications. Yet in another field—evolutionary biology—the received wisdom is the reverse: that men are more variable, possibly due to male heterogamety. To test these competing hypotheses, we compared variance between the sexes for 50 morphological and physiological traits, analysing data from the NHANES database. Nearly half the traits did no
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Sun, Duo, Kang Xi, Runxu Yang, et al. "Gray matter volume differences based on sex in first-episode drug-naive patients with major depressive disorder and its molecular analysis." NeuroReport, October 11, 2024. http://dx.doi.org/10.1097/wnr.0000000000002107.

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This study analyzed whether gray matter volume (GMV) differences exist between the sexes in patients with major depressive disorder (MDD) and explored the relationships between these differences and neurotransmitter systems. This study enrolled 190 first-episode drug-naive patients with MDD and 293 healthy controls. All participants underwent T1-weighted high-resolution MRI. The interaction between the diagnosis (healthy controls vs. MDD) and sex (male vs. female) regarding GMV alterations was analyzed. The JuSpace toolbox, which covers a wide range of neurotransmitter systems, was used to ide
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Tian, Aixian, Hongzhi Gao, Zhan Wang, et al. "Brain structural correlates of postoperative axial pain in degenerative cervical myelopathy patients following posterior cervical decompression surgery: a voxel-based morphometry study." BMC Medical Imaging 23, no. 1 (2023). http://dx.doi.org/10.1186/s12880-023-01057-8.

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Abstract Objective To investigate the brain structural correlates of postoperative axial pain (PAP) in degenerative cervical myelopathy (DCM) following posterior cervical decompression surgery. Methods Structural images with high-resolution T1 weighting were collected from 62 patients with DCM and analyzed, in addition to 42 age/gender matched subjects who were healthy. Voxel-based morphometry (VBM) was analyzed, grey matter volume (GMV) was computed. One-way ANOVA was performed to reveal the GMV differences among DCM patients with PAP, patients without PAP and healthy controls (HC). Post-hoc
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38

Wegner, Elfie, Adonis Cheng, Christina Johnson, Antonia Carbone, Nick Florio, and Judy C. Washington. "Evaluating Diabetes Group Medical Visits in a Family Medicine Residency Program." PRiMER 7 (January 18, 2023). http://dx.doi.org/10.22454/primer.2023.128268.

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Background: Group medical visits (GMV) have been shown to improve metrics in patients with type 2 diabetes mellitus (DM). Overlook Family Medicine, a teaching residency program, anticipated that medical residents trained in the GMV model of care by interdisciplinary team members may improve cholesterol, HbA1C, BMI, and blood pressure in patients. The objective of this study was to compare metrics between group 1: GMV patients with DM whose primary care provider (PCP) was an attending physician/nurse practitioner (NP) and group 2: GMV patients with DM whose PCP was a family medicine (FM) medica
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Peitz, Katharina, Johanna Stumme, Christiane Jockwitz, Nora Bittner, Svenja Caspers, and Stefan Heim. "The influence of bilingualism on gray matter volume in the course of aging: a longitudinal study." Frontiers in Aging Neuroscience 15 (July 20, 2023). http://dx.doi.org/10.3389/fnagi.2023.1193283.

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BackgroundBilingualism is associated with higher gray matter volume (GMV) as a form of brain reserve in brain regions such as the inferior frontal gyrus (IFG) and the inferior parietal lobule (IPL). A recent cross-sectional study reported the age-related GMV decline in the left IFG and IPL to be steeper for bilinguals than for monolinguals. The present study aimed at supporting this finding for the first time with longitudinal data.MethodsIn the current study, 200 participants aged 19 to 79 years (87 monolinguals, 113 sequential bilinguals, mostly native German speakers with variable second la
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Gao, Yian, Chaofan Sui, Boyao Chen, et al. "Voxel-based morphometry reveals the correlation between gray matter volume and serum P-tau-181 in type 2 diabetes mellitus patients with different HbA1c levels." Frontiers in Neuroscience 17 (May 15, 2023). http://dx.doi.org/10.3389/fnins.2023.1202374.

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IntroductionEmerging evidence suggested widespread decreased gray matter volume (GMV) and tau hyperphosphorylation were associated with type 2 diabetes mellitus (T2DM). Insulin resistance is one of the mechanisms of neuron degeneration in T2DM; it can decrease the activity of protein kinase B and increase the activity of glycogen synthesis kinase-3β, thus promoting the hyperphosphorylation of tau protein and finally leading to neuronal degeneration. However, the association between GMV and serum tau protein phosphorylated at threonine 181 (P-tau-181) in T2DM patients lacks neuroimaging evidenc
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Jakubík, Ján. "Isometries and direct product decompositions of GMV-algebras." Mathematica Slovaca 60, no. 5 (2010). http://dx.doi.org/10.2478/s12175-010-0034-6.

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AbstractWe apply the concept of generalized MV-algebra (GMV-algebra, for short) in the sense defined and studied by Galatos and Tsinakis. We introduce the notion of isometry of a GMV-algebra; we investigate the relations between isometries and direct product decompositions of GMV-algebras. Using these relations we show that if a GMV-algebra M has a greatest element, then each isometry of M is idempotent.
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Postma, E. M., P. A. M. Smeets, W. M. Boek, and S. Boesveldt. "Investigating morphological changes in the brain in relation to etiology and duration of olfactory dysfunction with voxel-based morphometry." Scientific Reports 11, no. 1 (2021). http://dx.doi.org/10.1038/s41598-021-92224-w.

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AbstractOlfactory loss (OL) affects up to 20% of the general population and is related to changes in olfaction-related brain regions. This study investigated the effect of etiology and duration of OL on gray matter volume (GMV) of these regions in 257 patients. Voxel-based morphometry was applied to measure GMV in brain regions of interest to test the effects of etiology and duration on regional GMV and the relation between olfactory function and regional GMV. Etiology of OL had a significant effect on GMV in clusters representing the gyrus rectus and orbitofrontal cortex (OFC), bilaterally. P
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Cai, Wangli, Yujing Zhou, Lidi Wan, et al. "Transcriptomic Signatures Associated With Gray Matter Volume Changes in Patients With Functional Constipation." Frontiers in Neuroscience 15 (January 5, 2022). http://dx.doi.org/10.3389/fnins.2021.791831.

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Functional constipation, which belongs to the functional gastrointestinal disorder (FGID), is a common disease and significantly impacts daily life. FGID patients have been progressively proven with functional and structural alterations in various brain regions, but whether and how functional constipation affects the brain gray matter volume (GMV) remains unclear; besides, which genes are associated with the GMV changes in functional constipation is largely unknown. On account of the structural MRI image from the 30 functional constipation patients and 30 healthy controls (HCs), GMV analysis s
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Gao, Songzhan, Jianhuai Chen, Jia Liu, et al. "Decreased grey matter volume in dorsolateral prefrontal cortex and thalamus accompanied by compensatory increases in middle cingulate gyrus of premature ejaculation patients." Andrology, October 30, 2023. http://dx.doi.org/10.1111/andr.13547.

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AbstractIntroductionThe prefrontal–cingulate–thalamic areas are associated with ejaculation control. Functional abnormalities of these areas and decreased grey matter volume (GMV) in the subcortical areas have been confirmed in premature ejaculation (PE) patients. However, no study has explored the corresponding GMV changes in the prefrontal–cingulate–thalamic areas, which are considered as the important basis for functional abnormalities. This study aimed to investigated whether PE patients exhibited impaired GMV in the brain, especially the prefrontal–cingulate–thalamic areas, and whether th
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Campo, Cecilia Gonzalez, Fernando Henriquez, Patricio Riquelme Contreras, et al. "Impact of Grey Matter Volume and White Matter Hyperintensities on Functional Capacity for Activities of Daily Living: A Study in the Alzheimer's Disease Continuum." Alzheimer's & Dementia 20, S2 (2024). https://doi.org/10.1002/alz.089402.

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AbstractBackgroundThe Alzheimer's disease (AD) continuum is composed of the stages of Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI), and Alzheimer's Disease Dementia (ADD). The decrease in gray matter volume (GMV) secondary to cortical atrophy, commonly seen in this continuum, is related to cognitive and activities of daily living (ADL) impairment. Additionally, White Matter Hyperintensities (WMH), MRI abnormalities frequently observed in older adults and patients with dementia, are also associated with cognitive and ADL performance. This study aimed to evaluate the relat
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Campo, Cecilia Gonzalez, Fernando Henriquez, Patricio Riquelme Contreras, et al. "Impact of Grey Matter Volume and White Matter Hyperintensities on Functional Capacity for Activities of Daily Living: A Study in the Alzheimer’s Disease Continuum." Alzheimer's & Dementia 20, S9 (2024). https://doi.org/10.1002/alz.093831.

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AbstractBackgroundThe Alzheimer’s disease (AD) continuum is composed of the stages of Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI), and Alzheimer’s Disease Dementia (ADD). The decrease in gray matter volume (GMV) secondary to cortical atrophy, commonly seen in this continuum, is related to cognitive and activities of daily living (ADL) impairment. Additionally, White Matter Hyperintensities (WMH), MRI abnormalities frequently observed in older adults and patients with dementia, are also associated with cognitive and ADL performance. This study aimed to evaluate the relat
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47

Yao, Chenyang, Na Hu, Hengyi Cao, et al. "A Multimodal Fusion Analysis of Pretreatment Anatomical and Functional Cortical Abnormalities in Responsive and Non-responsive Schizophrenia." Frontiers in Psychiatry 12 (December 1, 2021). http://dx.doi.org/10.3389/fpsyt.2021.737179.

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Background: Antipsychotic medications provide limited long-term benefit to ~30% of schizophrenia patients. Multimodal magnetic resonance imaging (MRI) data have been used to investigate brain features between responders and nonresponders to antipsychotic treatment; however, these analytical techniques are unable to weigh the interrelationships between modalities. Here, we used multiset canonical correlation and joint independent component analysis (mCCA + jICA) to fuse MRI data to examine the shared and specific multimodal features between the patients and healthy controls (HCs) and between th
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48

Peitz, Katharina, Nora Bittner, Stefan Heim, and Svenja Caspers. "Bilingualism and “brain reserve” in subregions of the hippocampal formation." GeroScience, April 8, 2025. https://doi.org/10.1007/s11357-025-01639-0.

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Abstract With aging, the hippocampal formation shows variable structural atrophy, which is associated with a decline in cognitive performance. Bilingualism is related to higher hippocampal gray matter volume (GMV), potentially representing a form of brain reserve in aging. However, the differential influence of bilingualism on hippocampal subregions remains unclear. Thus, we investigated GMV differences and differences in age-GMV relationships between mono- and bilinguals in the hippocampal formation and its subregions, hippocampus proper and subicular complex. We included 661 adults aged 19 t
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Wang, Xi, Yuming Li, Boyi Li, Huifang Shang, and Jing Yang. "Gray matter alterations in Huntington's disease: A meta‐analysis of VBM neuroimaging studies." Journal of Neuroscience Research 102, no. 7 (2024). http://dx.doi.org/10.1002/jnr.25366.

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AbstractIncreasing neuroimaging studies have attempted to identify biomarkers of Huntington's disease (HD) progression. Here, we conducted voxel‐based meta‐analyses of voxel‐based morphometry (VBM) studies on HD to investigate the evolution of gray matter volume (GMV) alterations and explore the effects of genetic and clinical features on GMV changes. A systematic review was performed to identify the relevant studies. Meta‐analyses of whole‐brain VBM studies were performed to assess the regional GMV changes in all HD mutation carriers, in presymptomatic HD (pre‐HD), and in symptomatic HD (sym‐
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Krause-Sorio, Beatrix, Prabha Siddarth, Michaela M. Milillo, et al. "Grey matter volume predicts improvement in geriatric depression in response to Tai Chi compared to Health Education." International Psychogeriatrics, December 6, 2023, 1–9. http://dx.doi.org/10.1017/s1041610223004386.

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ABSTRACT Objectives: Geriatric depression (GD) is associated with cognitive impairment and brain atrophy. Tai-Chi-Chih (TCC) is a promising adjunct treatment to antidepressants. We previously found beneficial effects of TCC on resting state connectivity in GD. We now tested the effect of TCC on gray matter volume (GMV) change and the association between baseline GMV and clinical outcome. Participants: Forty-nine participants with GD (>=60 y) underwent antidepressant treatment (38 women). Intervention: Participants completed 3 months of TCC (N = 26) or health and wellness education control (
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