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Journal articles on the topic 'GNRI'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Cetintepe, Tugba, Lutfi Cetintepe, Demet Kiper Unal, Kemal Aygun, and Serife Solmaz. "HALP score and GNRI: Simple and powerful prognostic markers in diffuse large B-cell lymphoma." Medicine 104, no. 22 (2025): e42165. https://doi.org/10.1097/md.0000000000042165.

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Diffuse large B cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma. It is a heterogeneous group of diseases that may need very aggressive treatment in some cases. Prognostic evaluation is very important in determining the best treatment. However, in some clinics, access to genetically based and expensive diagnostic methods is limited. In this study, we analyzed the prognostic value of Hemoglobin, Albumin, Lymphocyte and Platelet (HALP) Score and Geriatric Nutritional Risk Index (GNRI) in DLBCL patients. 201 Patients with newly diagnosed DLBLC between 2005 and 2022 were re

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FURUKE, HIROTAKA, DAIKI MATSUBARA, TAKESHI KUBOTA, et al. "Geriatric Nutritional Risk Index Predicts Poor Prognosis of Patients After Curative Surgery for Gastric Cancer." Cancer Diagnosis & Prognosis 1, no. 2 (2021): 43–52. http://dx.doi.org/10.21873/cdp.10007.

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Background: The Geriatric Nutritional Risk Index (GNRI) is a nutritional measure for predicting the risk of morbidity and mortality in hospitalized patients. We evaluated the utility of the GNRI to predict the short-term and long-term outcomes after curative surgery for gastric cancer (GC). Patients and Methods: Patients who underwent curative surgery for GC between 2008 and 2016 were reviewed (n=795). We classified patients into two groups according to the GNRI (high GNRI: low and no risk; low GNRI: major and moderate risk) and compared the utility of the GNRI. Results: A low GNRI was an inde

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Sakamoto, Teruhisa, Masahiro Makinoya, Teppei Sunaguchi, et al. "Geriatric nutritional risk index as a prognostic factor in patients with recurrent pancreatic cancer." PLOS ONE 17, no. 7 (2022): e0271073. http://dx.doi.org/10.1371/journal.pone.0271073.

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The aim of this study is to investigate the prognostic significance of geriatric nutritional risk index (GNRI) at the time of recurrence in patients with recurrent pancreatic cancer, and the relationship between GNRI and skeletal muscle mass for survival outcomes after recurrence. This study enrolled 77 patients who developed postoperative recurrence. The skeletal muscle mass index (SMI) was used in this study. The patients were divided into a high-GNRI group (n = 36) and a low-GNRI group (n = 41) for the GNRI, and were divided into a high-SMI group (n = 38) and a low-SMI group (n = 39) for SM

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Hua, Jianian, Jieyi Lu, Xiang Tang, and Qi Fang. "Association between Geriatric Nutritional Risk Index and Depression after Ischemic Stroke." Nutrients 14, no. 13 (2022): 2698. http://dx.doi.org/10.3390/nu14132698.

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Background: Malnutrition is associated with poor outcomes after stroke. However, the association between malnutrition and post-stroke depression (PSD) remains unelucidated. We aimed to explore the association between geriatric nutritional risk index (GNRI) and depression after ischemic stroke. Methods: In total, 344 patients with ischemic stroke were included in this analysis. The GNRI was calculated from serum albumin level, weight, and height at admission. Malnutrition was defined using the GNRI cutoff points. A lower GNRI score indicates an elevated nutritional risk. The outcome was depress

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Takahashi, Fuyuko, Yoshitaka Hashimoto, Ayumi Kaji, et al. "Association between Geriatric Nutrition Risk Index and The Presence of Sarcopenia in People with Type 2 Diabetes Mellitus: A Cross-Sectional Study." Nutrients 13, no. 11 (2021): 3729. http://dx.doi.org/10.3390/nu13113729.

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The aim of this cross-sectional study was to examine the association between the geriatric nutritional risk index (GNRI) and the prevalence of sarcopenia in people with type 2 diabetes (T2DM). Having both low handgrip strength (<28 kg for men and <18 kg for women) and low skeletal muscle mass index (<7.0 kg/m2 for men and <5.7 kg/m2 for women) was diagnosed as sarcopenia. GNRI was estimated by the formula as below: GNRI = (1.489 × serum albumin level [g/L]) + (41.7 × [current body weight (kg)/ideal body weight (kg)]). Participants were dichotomized on the basis of their GNRI scores

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Kim, Do Hyoung, Young-Ki Lee, Hayne Cho Park, et al. "The Geriatric Nutritional Risk Index Is an Optimal Evaluation Parameter for Predicting Mortality in Adult All Ages Hemodialysis Patients: A Korean Population-Based Study." Nutrients 15, no. 17 (2023): 3831. http://dx.doi.org/10.3390/nu15173831.

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The Geriatric Nutritional Risk Index (GNRI) is a nutritional screening tool used for predicting mortality in patients undergoing hemodialysis (HD). This study investigated the cutoff values for the GNRI for predicting mortality in HD patients using Korean HD quality assessment data from 2015. To identify the optimal GNRI cutoff value, we used Harrell’s C-index with multivariate Cox regression models. The highest value of C-index was identified as the cutoff value of GNRI for all-cause mortality in this population. In total, 34,933 patients were included; 90.8 of GNRI was the highest value of C

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Kamitani, Iku, Hiroki Yokoyama, Hiroto Ishii, et al. "Geriatric Nutritional Risk Index Is an Important Predictor of Survival in Allogeneic Hematopoietic Stem Cell Transplant Recipients." Blood 142, Supplement 1 (2023): 4968. http://dx.doi.org/10.1182/blood-2023-185882.

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Introduction:The body mass index (BMI) and geriatric nutritional risk index (GNRI) are nutrition-related risk assessment tool and has been used in various clinical settings. The relationship between BMI and the associated risk of hematopoietic stem cell transplantation (HSCT), such as relapse and non-relapse mortality (NRM), have been reported (Fuji S et al. BMT. 2014;49:1505). However, the relationship between GNRI and HSCT outcome remains inconclusive. We aimed to evaluate the association between GNRI and overall survival (OS), relapse, and NRM of patients who received allogenic HSCT for hem

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Yang, Yuting, Yujuan Yang, Yanping Hu, et al. "Association of Geriatric Nutritional Risk Index Scores with Outcomes in Patients Undergoing Maintenance Hemodialysis." British Journal of Hospital Medicine 86, no. 1 (2025): 1–18. https://doi.org/10.12968/hmed.2024.0501.

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Aims/Background The Geriatric Nutritional Risk Index (GNRI) is an effective tool for identifying malnutrition, and helps monitor the prognosis of patients undergoing maintenance hemodialysis. However, the association between the GNRI and cardiovascular or all-cause mortality in hemodialysis patients remains unclear. Therefore, this study investigated the correlation of the GNRI with all-cause and cardiovascular mortality in patients undergoing maintenance hemodialysis. Methods This study included 402 incident hemodialysis patients. Based on the first-dialysis GNRI quartile, the patients were d

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Fujita, Tsutomu, Satoshi Hamai, Toshimi Konishi, et al. "Impact of preoperative nutritional impairment on physical function early after total hip arthroplasty." Bone & Joint Open 6, no. 6 (2025): 667–76. https://doi.org/10.1302/2633-1462.66.bjo-2024-0261.r1.

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AimsTo investigate whether preoperative nutritional status, assessed by the Geriatric Nutritional Risk Index (GNRI), predicts postoperative physical function following total hip arthroplasty (THA).MethodsA total of 681 patients (87 males, 594 females; mean age 65.3 years (SD 10.2)) who underwent unilateral primary THA for hip osteoarthritis were included. GNRI was calculated from preoperative serum albumin levels, categorizing patients into three groups: normal nutrition (GNRI ≥ 98), moderate malnutrition (92 ≤ GNRI < 98), and severe malnutrition (GNRI < 92). Physical function, including

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Liao, Chun-Kai, Yih-Jong Chern, Yu-Jen Hsu, et al. "The Clinical Utility of the Geriatric Nutritional Risk Index in Predicting Postoperative Complications and Long-Term Survival in Elderly Patients with Colorectal Cancer after Curative Surgery." Cancers 13, no. 22 (2021): 5852. http://dx.doi.org/10.3390/cancers13225852.

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Research on the relationship between the geriatric nutritional risk index (GNRI) and postoperative complications/oncological outcomes in elderly colorectal cancer (CRC) patients is limited. This study investigated the prognostic value of the GNRI in aged CRC patients. We retrospectively analyzed 1206 consecutive CRC patients aged over 75 years who underwent curative-intent surgery from January 2008 to December 2015 and categorized them into high GNRI (≥98) and low GNRI (<98) groups according to a receiver operating characteristic (ROC) curve analysis. Uni- and multivariate logistic regressi

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Huang, Ching-Ya, Yuan-Hao Yen, Ting-Min Hsieh, Ching-Hua Tsai, Shiun-Yuan Hsu, and Ching-Hua Hsieh. "Evaluating the Impact of Nutritional Risk on Stress-Induced Hyperglycemia and Trauma Patient Outcomes." Healthcare 12, no. 17 (2024): 1746. http://dx.doi.org/10.3390/healthcare12171746.

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Introduction: Stress-induced hyperglycemia (SIH) and malnutrition are common in trauma patients and are linked to worse outcomes. This study examined the influence of nutritional status, determined by the Geriatric Nutritional Risk Index (GNRI), on the incidence of SIH in trauma patients. Methods: A retrospective analysis was conducted on adult trauma patients admitted to a Level I trauma center from 1 January 2009 to December 31, 2021. Patients were categorized into four groups: SIH, diabetic hyperglycemia (DH), diabetic normoglycemia (DN), and non-diabetic normoglycemia (NDN). Nutritional st

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Ono, Masafumi, Atsushi Mizuno, Shun Kohsaka, et al. "Geriatric Nutritional Risk Index at Hospital Admission or Discharge in Patients with Acute Decompensated Heart Failure." Journal of Clinical Medicine 12, no. 5 (2023): 1891. http://dx.doi.org/10.3390/jcm12051891.

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Geriatric Nutritional Risk Index (GNRI) is known both as a reliable indicator of nutritional status and a predictor of long-term survival among patients with acute decompensated heart failure (ADHF). However, the optimal timing to evaluate GNRI during hospitalization remains unclear. In the present study, we retrospectively analyzed patients hospitalized with ADHF in the West Tokyo Heart Failure (WET-HF) registry. GNRI was assessed at hospital admission (a-GNRI) and discharge (d-GNRI). Out of 1474 patients included in the present study, 568 (40.1%) and 796 (57.2%) patients had lower GNRI (<

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Sato, Kohei, Kazuhito Suzuki, Riku Nagao, et al. "Gnri (Geriatric Nutritional Risk Index) in Multiple Myeloma." Blood 144, Supplement 1 (2024): 1939. https://doi.org/10.1182/blood-2024-203587.

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Introduction Multiple myeloma is developed in elderly individuals, and their symptoms lead frailty. Frailty score has been reported as powerful predictive factor for overall survival (OS) in myeloma, and developed using age, activities of daily living (ADL), instrumental ADL (IADL), performance status (PS), and several factors. Meanwhile, nutritious condition might also predict OS in myeloma. Geriatric nutritional risk index (GNRI) predicted OS in not only patients with solid cancers, including lymphomas, but also elderly healthy individual. However, GNRI has never been investigated in myeloma

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Enomoto, Hirayuki, Yukihisa Yuri, Takashi Nishimura, et al. "A Low Geriatric Nutritional Risk Index Is Associated with Low Muscle Volume and a Poor Prognosis among Cirrhotic Patients." Medicina 59, no. 12 (2023): 2099. http://dx.doi.org/10.3390/medicina59122099.

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Background and Objectives: The geriatric nutritional risk index (GNRI) is an easily calculable index that can be determined using three common clinical variables. The GNRI is suggested to be related to sarcopenia in cirrhotic patients. However, the relationship between the GNRI and the prognosis in patients with liver cirrhosis (LC) has not been reported. The aim of the present research is to study the association of the GNRI with the nutritional status, hepatic function reserve, and prognosis in patients with liver cirrhosis (LC). Materials and Methods: A total of 370 cirrhotic patients whose

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Li, Jing, Hai-Yan Shi, and Min Zhou. "Correlation between preoperative systemic immune inflammation index, nutritional risk index, and prognosis of radical resection of liver cancer." World Journal of Gastrointestinal Surgery 15, no. 11 (2023): 2445–55. http://dx.doi.org/10.4240/wjgs.v15.i11.2445.

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BACKGROUND Radical surgery is the most commonly used treatment for hepatocellular carcinoma (HCC). However, the surgical effect remains not ideal, and prognostic evaluation is insufficient. Furthermore, clinical intervention is rife with uncertainty and not conducive to prolonging patient survival. AIM To explore correlations between the systemic immune inflammatory index (SII) and geriatric nutritional risk index (GNRI) and HCC operation prognosis. METHODS This retrospective study included and collected follow up data from 100 HCC. Kaplan–Meier survival curves were used to analyze the correla

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Wang, Bei, Chuanhai Xu, Kaijun Ying, Jian Chu, and Wei Geng. "Prognostic value of hemoglobin combined with Geriatric Nutritional Risk Index scores in patients undergoing postoperative radiotherapy for esophageal squamous cell carcinoma." Future Oncology 18, no. 2 (2022): 179–91. http://dx.doi.org/10.2217/fon-2021-0439.

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Aims: To investigate the prognostic value of hemoglobin combined with geriatric nutritional risk index (GNRI) scores in patients undergoing postoperative radiotherapy for esophageal squamous cell carcinoma (ESCC). Patients & methods: Patients who underwent esophagectomy and postoperative radiotherapy were included in this retrospective study. Their preoperative hemoglobin and GNRI were collected to establish hemoglobin-GNRI (H-GNRI) scores, and their association with OS was evaluated. Results: Patients with high H-GNRI scores had better prognosis than those with low scores (p < 0.001).

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Elmas, Dursun, and Mahmut Sami İnce. "The role of Geriatric Nutritional Risk Index in sepsis-related mortality in intensive care." Journal of Health Sciences and Medicine 8, no. 2 (2025): 180–85. https://doi.org/10.32322/jhsm.1592706.

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Aims: This study explores the link between nutritional status and sepsis outcomes, focusing on Geriatric Nutritional Risk Index (GNRI) scores and clinical endpoints such as mortality, intensive care unit (ICU) stay duration, and functional recovery. Methods: The study was a retrospective, observational investigation of 250 older patients with sepsis in the intensive care unit. GNRI was calculated based on admission albumin level and ratio of actual body weight to ideal body weight. Groups were defined as major risk (GNRI 98), 9.8% in the low risk group (GNRI 92-98), 8.5% in the moderate risk g

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Yajima, Takahiro, Kumiko Yajima, and Hiroshi Takahashi. "Impact of Annual Change in Geriatric Nutritional Risk Index on Mortality in Patients Undergoing Hemodialysis." Nutrients 12, no. 11 (2020): 3333. http://dx.doi.org/10.3390/nu12113333.

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Regular nutritional assessment may decrease the mortality rate in patients undergoing hemodialysis. This study aimed to evaluate whether annual change in geriatric nutritional risk index (ΔGNRI) can precisely predict mortality. We retrospectively examined 229 patients undergoing hemodialysis who measured geriatric nutritional risk index (GNRI). Patients were divided into four groups according to the baseline GNRI of 91.2, previously reported cutoff value, and declined or maintained GNRI during the first year (ΔGNRI < 0% vs. ΔGNRI ≥ 0%): Group 1 (G1), GNRI ≥ 91.2 and ΔGNRI ≥ 0%; G2, GNRI ≥ 9

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Ardhaoui, M., J. Mahbouba, S. Zrour, I. Bejia, M. Touzi, and N. Bergaoui. "AB0243 ASSOCIATION BETWEEN THE GERIATRIC NUTRITIONAL RISK INDEX (GNRI) AND THE DISEASE ACTIVITY IN ELDERLY PATIENTS WITH RHEUMATOID ARTHRITIS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1306.1–1306. http://dx.doi.org/10.1136/annrheumdis-2023-eular.3635.

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BackgroundThe Geriatric Nutritional Risk Index (GNRI) is a tool that assesses the risk of malnutrition-related complications in elderly patients. Some recent publications have suggested that the GNRI could predict disease activity in people followed for rheumatoid arthritis (RA) [1].ObjectivesOur aim was to evaluate the correlation between the GNRI and the disease activity in elderly RA patient.s.MethodsThis is a cross-sectional study including patients followed for RA and aged at least 65 years.The GNRI was calculated for all patients:GNRI = [1.489*albumin (g/L)] + [41.7 *(weight/WLo)], where

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Haas, Markus, Alexander Lein, Thorsten Fuereder, et al. "The Geriatric Nutritional Risk Index (GNRI) as a Prognostic Biomarker for Immune Checkpoint Inhibitor Response in Recurrent and/or Metastatic Head and Neck Cancer." Nutrients 15, no. 4 (2023): 880. http://dx.doi.org/10.3390/nu15040880.

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Malnutrition is a frequent comorbidity in head and neck cancer patients and has been shown to impair immunotherapy response in other cancer types. The geriatric nutritional risk index (GNRI) assesses malnutrition using the patient’s ideal weight, actual weight, and serum albumin. The aim of this study was to evaluate the prognostic relevance of malnutrition as determined by the GNRI for the response to immunotherapy in recurrent and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC). A total of 162 patients with R/M HNSCC who received immune checkpoint inhibitors were included. Th

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Yajima, Takahiro, Kumiko Yajima, and Hiroshi Takahashi. "Association of the erythropoiesis-stimulating agent resistance index and the geriatric nutritional risk index with cardiovascular mortality in maintenance hemodialysis patients." PLOS ONE 16, no. 1 (2021): e0245625. http://dx.doi.org/10.1371/journal.pone.0245625.

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Objective Hyporesponsiveness to erythropoiesis-stimulating agent (ESA) may be associated with protein-energy wasting. We investigated the relationship of the ESA resistance index (ERI) and the geriatric nutritional risk index (GNRI) for cardiovascular mortality in hemodialysis (HD) patients. Methods A total of 180 maintenance HD patients were enrolled. The patients were stratified by the GNRI of 91.2, a previously reported cut-off value, and the ERI of 13.7 (IU/week/kg/g/dL), a cut-off value for predicting cardiovascular-specific mortality, and they were classified into four groups (group 1[G1

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Yamana, Ippei, Shinsuke Takeno, Ryosuke Shibata, et al. "Is the Geriatric Nutritional Risk Index a Significant Predictor of Postoperative Complications in Patients with Esophageal Cancer Undergoing Esophagectomy?" European Surgical Research 55, no. 1-2 (2015): 35–42. http://dx.doi.org/10.1159/000376610.

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Background: The Geriatric Nutritional Risk Index (GNRI) is a new index recently introduced for predicting the risk of nutrition-related complications. The GNRI has mainly been reported as a simple and accurate tool to assess the nutritional status and prognosis of elderly patients. So far, there have been no reports of the GNRI in patients with gastrointestinal cancer. Our objective was to examine the association between the GNRI and short-term outcomes, especially postoperative complications, in patients with esophageal cancer who underwent esophagectomy and gastric tube reconstruction. Mater

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Chen, Ying, Xinguang Yang, Yingying Zhu, Xiaoni Zhang, Jingxian Ni, and Yi Li. "Malnutrition Defined by Geriatric Nutritional Risk Index Predicts Outcomes in Severe Stroke Patients: A Propensity Score-Matched Analysis." Nutrients 14, no. 22 (2022): 4786. http://dx.doi.org/10.3390/nu14224786.

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Background: Malnutrition’s prognostic impact in patients with severe stroke requiring ICU admission is not well known. This study aimed to assess the nutritional status of severe stroke patients using the geriatric nutritional risk index (GNRI) and examine the association of GNRI with mortality in that population. Methods: We identified 1145 severe stroke patients requiring ICU admission from the Medical Information Mart for Intensive Care (MIMIC-III) database and divided them into low GNRI (≤98) or high GNRI (>98) groups. We used a propensity score matching (PSM) method to reduce confoundi

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Liu, Bao, and Limin Zhang. "Geriatric nutritional risk index predicts the prognosis of gastric cancer patients treated with immune checkpoint inhibitors." Medicine 103, no. 17 (2024): e37863. http://dx.doi.org/10.1097/md.0000000000037863.

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The nutritional status is closely linked to the immune function of patients. Previous studies have demonstrated the utility of the Geriatric Nutritional Risk Index (GNRI) in assessing nutritional status. The aim of this study is to investigate the prognostic significance of GNRI in patients with gastric cancer who received immune checkpoint inhibitor (ICI) therapy. The study enrolled 89 gastric cancer patients who received different types of immune checkpoint inhibitors (ICIs) between August 2016 and December 2020, along with 57 patients who underwent chemotherapy during the same period as a c

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KINOSHITA, RYOSUKE, MAKOTO NAKAO, HIROKO KIYOTOSHI, et al. "Geriatric Nutritional Risk Index as Prognostic Marker for Elderly Patients With Small Cell Lung Cancer." Cancer Diagnosis & Prognosis 4, no. 4 (2024): 482–88. http://dx.doi.org/10.21873/cdp.10352.

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Background/Aim: The Geriatric Nutritional Risk Index (GNRI) indicates nutritional status based on serum albumin concentration and ideal body weight. Pretreatment GNRI has been suggested as a prognostic factor for various malignancies. However, little is known about the clinical value of GNRI for small-cell lung cancer (SCLC), especially in elderly patients. : Patients and Methods: We retrospectively analyzed 53 elderly (≥71) patients with extensive-disease (ED) SCLC treated with first-line platinum-doublet chemotherapy in relation to the pretreatment GNRI level in a real-world setting. : Resul

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Tsukagoshi, Mariko, Kenichiro Araki, Takamichi Igarashi, et al. "Lower Geriatric Nutritional Risk Index and Prognostic Nutritional Index Predict Postoperative Prognosis in Patients with Hepatocellular Carcinoma." Nutrients 16, no. 7 (2024): 940. http://dx.doi.org/10.3390/nu16070940.

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Increasing evidence suggests that nutritional indices, including the geriatric nutritional risk index (GNRI) and prognostic nutritional index (PNI), are predictors of poor prognosis in patients with hepatocellular carcinoma (HCC). Hence, this study aimed to explore the value of the GNRI and PNI in evaluating postoperative prognosis in patients with HCC, particularly regarding its recurrence patterns. We performed a retrospective analysis of 203 patients with HCC who underwent initial hepatic resection. Patients were divided into two groups according to the GNRI (cutoff: 98) and PNI (cutoff: 45

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Lin, Ting-Yun, and Szu-Chun Hung. "Geriatric Nutritional Risk Index Is Associated with Unique Health Conditions and Clinical Outcomes in Chronic Kidney Disease Patients." Nutrients 11, no. 11 (2019): 2769. http://dx.doi.org/10.3390/nu11112769.

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Malnutrition is prevalent in patients with chronic kidney disease (CKD). However, current nutrition screening tools are not specific to the CKD population. In the present study, we aimed to investigate whether the geriatric nutritional risk index (GNRI), a simple tool designed for assessing nutrition-related risks in the elderly population, is associated with unique aspects of CKD such as fluid status, residual renal function, proteinuria, and inflammation, and whether it predicts clinical outcomes. The GNRI was calculated by incorporating serum albumin and anthropometric measurements in 326 p

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Yajima, Takahiro, Kumiko Yajima, Hiroshi Takahashi, and Keigo Yasuda. "Combined Predictive Value of Extracellular Fluid/Intracellular Fluid Ratio and the Geriatric Nutritional Risk Index for Mortality in Patients Undergoing Hemodialysis." Nutrients 11, no. 11 (2019): 2659. http://dx.doi.org/10.3390/nu11112659.

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The ratio of extracellular fluid (ECF) to intracellular fluid (ICF) may be associated with mortality in patients undergoing hemodialysis, possibly associated with protein-energy wasting. We therefore investigated the relationship of the ECF/ICF ratio and the geriatric nutritional risk index (GNRI) with the all-cause and cardiovascular-specific mortality in 234 patients undergoing hemodialysis. Bioimpedance analysis of the ECF and ICF was performed and the ECF/ICF ratio was independently associated with GNRI (β = −0.247, p < 0.0001). During a median follow-up of 2.8 years, 72 patients died,

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Komatsu, Mizuki, Masayuki Okazaki, Ken Tsuchiya, Hiroshi Kawaguchi, and Kosaku Nitta. "Geriatric Nutritional Risk Index Is a Simple Predictor of Mortality in Chronic Hemodialysis Patients." Blood Purification 39, no. 4 (2015): 281–87. http://dx.doi.org/10.1159/000381798.

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Background: Malnutrition is common in hemodialysis (HD) patients, and it is associated with increasing risk of mortality. The geriatric nutritional risk index (GNRI) has been developed as a tool to assess the nutritional risk. The aim of this study was to examine the reliability of the GNRI as a mortality predictor in a Japanese HD cohort. Methods: We prospectively examined the GNRI of 332 maintenance HD patients aged 65.4 ± 13.2, 213 males, and followed up on them for 36 months. The patients were divided into quartiles (Q) according to GNRI values (Q1: <91.6, Q2: 91.7-97.0, Q3: 97.1-102.2,

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Riest, Jannis, Nele Friedrich, Matthias Nauck, Henry Völzke, Simone Gärtner, and Anke Hannemann. "The Association Between Nutritional Risk and Bone Stiffness in Elderly Men and Women in a Population-Based Study in Northeast Germany." Nutrients 16, no. 24 (2024): 4288. https://doi.org/10.3390/nu16244288.

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Background: The Geriatric Nutritional Risk Index (GNRI) has shown promising potential for identifying individuals at risk for osteoporosis in various patient cohorts. However, data from the general population confirming or refuting the usefulness of the GNRI as a risk factor for osteoporosis are sparse. We therefore aimed to clarify whether the GNRI is associated with the ultrasound-based bone stiffness index and the osteoporotic fracture risk in a sample of elderly men and women from the general population. Methods: Data from 1417 participants in the Study of Health in Pomerania START-2 or TR

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Naiki, Taku, Kiyoshi Takahara, Hiromitsu Watanabe, et al. "The Geriatric Nutritional Risk Index Predicts Prognosis in Japanese Patients with LATITUDE High-Risk Metastatic Hormone-Sensitive Prostate Cancer: A Multi-Center Study." Cancers 15, no. 22 (2023): 5333. http://dx.doi.org/10.3390/cancers15225333.

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Malnutrition is associated with prognosis in cancer. The geriatric nutritional risk index (GNRI), based on the ratio of actual to ideal body weight and also serum albumin level, is a simple screening tool for assessing nutrition. We investigated the GNRI as a prognostic factor for oncological outcomes in patients with high-risk metastatic hormone-sensitive prostate cancer (mHSPC) using a Japanese multicenter cohort. This study included a total of 175 patients with LATITUDE high-risk mHSPC, of whom 102 had received androgen deprivation therapy (ADT) plus upfront abiraterone acetate, and 73 had

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Lv, Guo-yue, Lin An, and Da-wei Sun. "Geriatric Nutritional Risk Index Predicts Adverse Outcomes in Human Malignancy: A Meta-Analysis." Disease Markers 2019 (November 19, 2019): 1–13. http://dx.doi.org/10.1155/2019/4796598.

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Background. Geriatric Nutritional Risk Index (GNRI) has been widely used to assess the nutritional status in a variety of human pathological conditions, but the prognostic value of the GNRI in malignancies has not been evinced. Methods. Relevant studies updated on Jul 27, 2019, were retrieved in available databases, including PubMed, Web of Science, Cochrane library, Chinese CNKI, and Chinese Wan-fang. Hazard ratios (HRs) and 95% confidence intervals (CIs) were extracted and pooled by using STATA 14. Results. A total of 15 studies involving 8,046 subjects were included in this meta-analysis. M

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Su, Zhongjian, Xing Zhang, Nan Zheng, et al. "Association of the Geriatric Nutritional Risk Index with incident hypertension in the older Chinese population: a 6-year cohort study." Journal of International Medical Research 49, no. 5 (2021): 030006052110100. http://dx.doi.org/10.1177/03000605211010051.

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Background We examined the association of the Geriatric Nutritional Risk Index (GNRI) with the incidence of hypertension. Methods We used data of the China Health and Nutrition Survey in this study. Participants aged ≥60 years were eligible. The GNRI was defined as follows: GNRI = [1.489 × albumin (ALB; g/L)] + [41.7 × (actual weight/ideal weight)]. Participants with systolic blood pressure ≥140 mmHg, diastolic blood pressure ≥90 mmHg, or use of antihypertensive medication were defined as having hypertension. Results This study included 4853 participants, comprising 3612 control participants a

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Kang, Seok Hui, Kyu Hyang Cho, Jong Won Park, Kyung Woo Yoon, and Jun Young Do. "Geriatric Nutritional Risk Index as a Prognostic Factor in Peritoneal Dialysis Patients." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 33, no. 4 (2013): 405–10. http://dx.doi.org/10.3747/pdi.2012.00018.

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BackgroundThe Geriatric Nutritional Risk Index (GNRI) might be a useful screening tool for malnutrition in dialysis patients. However, data concerning the GNRI as a prognostic factor in peritoneal dialysis (PD) patients are scarce.MethodsWe reviewed the medical records at Yeungnam University Hospital in Korea to identify all adults (>18 years) who received PD; 486 patients were enrolled in the study.ResultsThe initial low, middle, and high GNRI tertiles included 162, 166, and 158 patients respectively. Significant correlations were noted between the initial GNRI and body mass index, creatin

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Grinstead, Christina, and Saunjoo L. Yoon. "Geriatric Nutritional Risk Index (GNRI) and Survival in Pancreatic Cancer: A Retrospective Study." Nutrients 17, no. 3 (2025): 509. https://doi.org/10.3390/nu17030509.

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Introduction: Malnutrition is a major contributor to poor treatment and survival outcomes in pancreatic cancer, yet nutritional assessment is not standardized or consistently implemented in the care of oncology patients. The Geriatric Nutritional Risk Index (GNRI), calculated from serum albumin and body weight, may be useful as a practical tool for identifying patients at risk of poor nutritional status. Purpose: To provide a preliminary analysis using a limited selection of variables to examine the association of the GNRI at diagnosis and the GNRI change over time with overall survival in pat

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Lee, Minwoo, Jae-Sung Lim, Yerim Kim, et al. "Association between Geriatric Nutritional Risk Index and Post-Stroke Cognitive Outcomes." Nutrients 13, no. 6 (2021): 1776. http://dx.doi.org/10.3390/nu13061776.

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Background: It is not yet clear whether nutritional status is associated with post-stroke cognitive impairment (PSCI). We examined the geriatric nutritional risk index (GNRI) on the domain-specific cognitive outcomes 3 months after a stroke. Methods: A total of 344 patients with acute ischemic stroke were included for the analysis. The GNRI was calculated as 1.489 × serum albumin (g/L) + 41.7 × admission weight (kg)/ideal body weight (kg) and was dichotomized according to the prespecified cut-off points for no risk and any risks. The primary outcome was PSCI, defined as having adjusted z-score

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Yoshida, Maria, Ayumu Nakashima, Shigehiro Doi, et al. "Lower Geriatric Nutritional Risk Index (GNRI) Is Associated with Higher Risk of Fractures in Patients Undergoing Hemodialysis." Nutrients 13, no. 8 (2021): 2847. http://dx.doi.org/10.3390/nu13082847.

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Background: Although malnutrition and bone fracture are both major complications in patients undergoing hemodialysis, their association has not been clarified. The aim of our study was to clarify the association between the geriatric nutritional risk index (GNRI), an indicator of nutritional status, and the incidence of bone fractures in patients undergoing hemodialysis. Methods: We included 1342 registered patients undergoing hemodialysis and performed a post hoc analysis. We divided patients into the high GNRI group (≥92), considered to have a low risk of malnutrition, and the low GNRI group

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Xie, Yuanyuan, Hailing Zhang, Tingting Ye, Shengjie Ge, Ruyi Zhuo, and Hong Zhu. "The Geriatric Nutritional Risk Index Independently Predicts Mortality in Diabetic Foot Ulcers Patients Undergoing Amputations." Journal of Diabetes Research 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/5797194.

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Objective. Patients with diabetic foot ulcers undergoing amputations have poor prognosis. Malnutrition usually occurs in this population and is associated with increased risk of mortality. The geriatric nutritional risk index (GNRI) is a widely used, simple, and well-established tool to assess nutritional risk. The purpose of this study was to assess the association between GNRI and all-cause mortality in diabetic foot ulcers patients undergoing minor or major amputations.Methods. This was a retrospective cohort study including 271 adult patients. Patients were divided into two groups accordin

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Cho, AJin, Yun Soo Hong, Hayne Cho Park, Do Hyoung Kim, Young Joo Shin, and Young-Ki Lee. "Geriatric nutritional risk index is associated with retinopathy in patients with type 2 diabetes." Scientific Reports 12, no. 1 (2022). http://dx.doi.org/10.1038/s41598-022-15463-5.

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AbstractThe geriatric nutritional risk index (GNRI) is a nutrition-related risk assessment tool and has been used in various clinical settings. The relationship between body mass index (BMI) and the associated risk of diabetic retinopathy (DR) remains inconclusive. We aimed to evaluate the association between GNRI and DR in patients with type 2 diabetes. We included a total of 1359 patients with type 2 diabetes who followed up in our diabetes clinic and underwent fundus photographic examinations from August 2006 to February 2014. DR was assessed by retinal ophthalmologists using comprehensive

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Ying, Jieping, Suwen Zhu, Yingchun Cheng, Bei Wang, and Yueqin Wang. "Prognostic Role of Hemoglobin Combined With Geriatric Nutritional Risk Index in Patients With Vater Ampulla Carcinoma Undergoing Pancreaticoduodenectomy." Cancer Medicine 13, no. 19 (2024). http://dx.doi.org/10.1002/cam4.70334.

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ABSTRACTObjectivesThe purpose of this investigation was to assess the prognostic importance of the combination of preoperative hemoglobin (Hb) levels and Geriatric Nutritional Risk Index (GNRI) in forecasting postoperative survival outcomes for patients undergoing pancreaticoduodenectomy (PD) due to Vater ampulla carcinoma (VPC).MethodsThe GNRI nutritional screening was conducted for all patients, and patient outcomes, including overall survival (OS), were subsequently monitored. An H‐ GNRI scoring system was established using the optimal critical values of 125.5 g/L for Hb and 91.72 for GNRI,

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Güç, Zeynep Gülsüm, Ahmet Alacacıoğlu, Mehmet Eren Kalender, et al. "HALP score and GNRI: Simple and easily accessible indexes for predicting prognosis in advanced stage NSCLC patients. The İzmir oncology group (IZOG) study." Frontiers in Nutrition 9 (August 18, 2022). http://dx.doi.org/10.3389/fnut.2022.905292.

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ObjectiveThe Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) Score and the Geriatric Nutrition Risk Index (GNRI) are used as prognostic factors in different types of cancers. In this study we analyzed the prognostic value of the HALP Score and the GNRI calculated prior to first-line treatment in patients diagnosed with de novo metastatic non-small cell lung cancer (mNSCLC).Materials and methodsDe novo mNSCLC patients were retrospectively evaluated from January 2016 to December 2019. Patients with Driver’s mutation, severe comorbidities, active infection, or insufficient organ function, an

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Li, Zijiao, Li Zhang, Qiankun Yang, et al. "Association between geriatric nutritional risk index and depression prevalence in the elderly population in NHANES." BMC Public Health 24, no. 1 (2024). http://dx.doi.org/10.1186/s12889-024-17925-z.

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Abstract Background The prevalence of depression is increasing in the elderly population, and growing evidence suggests that malnutrition impacts mental health. Despites, research on the factors that predict depression is limited. Methods We included 2946 elderly individuals from National Health and Nutrition Examination Survey (NHANES) spanning the years 2011 through 2014. Depressive symptoms were assessed using the PHQ-9 scale. Multinomial logistic regression was performed to evaluate the independent association between Geriatric Nutritional Risk Index (GNRI) and depression prevalence and sc

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Fang, Pinhao, Qian Yang, Jianfeng Zhou, et al. "The impact of geriatric nutritional risk index on esophageal squamous cell carcinoma patients with neoadjuvant therapy followed by esophagectomy." Frontiers in Nutrition 9 (October 20, 2022). http://dx.doi.org/10.3389/fnut.2022.983038.

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BackgroundThe Geriatric Nutritional Index (GNRI) has been indicated as a nutritional index which is highly associated with complications and mortality in older hospitalized patients. Moreover, early studies had suggested that GNRI is a potential prognostic indicator for some malignances. However, the prognostic value of GNRI in esophageal squamous cell carcinoma (ESCC) patients underwent neoadjuvant therapy followed by esophagectomy remains elusive.Materials and methodsThis retrospective study incorporated 373 patients with ESCC who had underwent neoadjuvant therapy followed by radical esophag

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Saeki, Chisato, Akiyoshi Kinoshita, Tomoya Kanai, et al. "The Geriatric Nutritional Risk Index predicts sarcopenia in patients with cirrhosis." Scientific Reports 13, no. 1 (2023). http://dx.doi.org/10.1038/s41598-023-31065-1.

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AbstractPatients with cirrhosis are at high risk for sarcopenia and malnutrition, which are associated with reduced quality of life and increased mortality. We investigated the relationship between the Geriatric Nutritional Risk Index (GNRI) and sarcopenia/gait speed and assessed the usefulness of the GNRI for predicting sarcopenia in patients with cirrhosis. We evaluated 202 patients with cirrhosis and divided them into three groups based on baseline GNRI values: low (L)-GNRI (< 94.0, n = 49), intermediate (I)-GNRI (between 94.0 and 109.5, n = 103), and high (H)-GNRI groups (> 109.5, n

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Sato, Yu, Akiomi Yoshihisa, Yuji Nozaki, et al. "Abstract 9789: Geriatric Nutritional Risk Index Predicts Bleeding Event in Patients With Heart Failure." Circulation 146, Suppl_1 (2022). http://dx.doi.org/10.1161/circ.146.suppl_1.9789.

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Introduction: The relationship between malnutrition and bleeding event has been unclear in patients with heart failure (HF). Method and Results: We evaluated the nutritional status of patients with HF (n = 2,044) using Geriatric Nutritional Risk Index (GNRI). The primary endpoint was composite bleeding event of hemorrhagic stroke or gastrointestinal bleeding. According to the survival classification and regression tree analysis, the accurate cut-off point of GNRI for predicting the primary endpoint was 106.2. We divided patients into two groups based on GNRI levels: the High GNRI group (GNRI ≥

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Zou, YuPei, Jiarong Wang, Jichun Zhao, et al. "Predictive value of geriatric nutritional risk index in cardiac and cerebrovascular events after endovascular aortic aneurysm repair." Frontiers in Cardiovascular Medicine 11 (October 3, 2024). http://dx.doi.org/10.3389/fcvm.2024.1399908.

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ObjectiveTo evaluate the effect of malnutrition assessed by the Geriatric Nutritional Risk Index (GNRI) on major adverse cardiac and cerebrovascular events (MACCE) in the elderly patients after endovascular aortic aneurysm repair (EVAR).Materials and methodsThis was a retrospective cohort study of elderly patients who underwent EVAR in a tertiary hospital. Malnutrition status was assessed by the GNRI. The primary outcome was MACCE. The predictive ability of the GNRI was compared with both the Revised Cardiac Risk Index (RCRI) and the modified Frailty Index (mFI) using Receiver operating charac

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Huang, Wei, Yingqi Xiao, Hongwei Wang, and Kaixiang Li. "Association of geriatric nutritional risk index with the risk of osteoporosis in the elderly population in the NHANES." Frontiers in Endocrinology 13 (November 29, 2022). http://dx.doi.org/10.3389/fendo.2022.965487.

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BackgroundOsteoporosis is common in the elderly, and malnutrition is considered a major risk factor for osteoporosis. This study investigated the relationship between the Geriatric Nutrition Risk Index (GNRI) and osteoporosis based on a large cross-sectional study of the National Health and Nutrition Examination Survey (NHANES).MethodsWe included 7405 older adults from NHANES (2005 to 2018) and divided them into the High-GNRI and Low-GNRI groups based on GNRI levels to compare the prevalence of osteoporosis among the two groups. A multi-factor logistic regression analysis was used to determine

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Ito, N., D. Kanda, H. Shimono, et al. "Clinical impact of combined assessment of the CHADS2 score and geriatric nutritional risk index on clinical outcomes in patients with lower extremity artery disease without atrial fibrillation." European Heart Journal 45, Supplement_1 (2024). http://dx.doi.org/10.1093/eurheartj/ehae666.2274.

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Abstract Background The CHADS2 score is a well-known risk score for ischemic stroke in atrial fibrillation (AF) patients. Recently, it has been reported that the CHADS2 score was associated with an increased risk of new-onset lower extremity artery disease (LEAD) in patients without AF, the association between the CHADS2 score and clinical outcomes in patients with LEAD undergoing endovascular treatment (EVT) without AF remains unclear. Furthermore, malnutrition assessed by the geriatric nutritional risk index (GNRI) has been reported to be predictive of clinical outcomes in patients with LEAD

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Cho, AJin, Se Yeon Park, Yo Seop Cha, Hayne Cho Park, Do Hyoung Kim, and Young-Ki Lee. "The change in Geriatric Nutritional Risk Index is associated with mortality in patients who start hemodialysis: Korean Renal Data Registry, 2016–2018." Scientific Reports 12, no. 1 (2022). http://dx.doi.org/10.1038/s41598-022-24981-1.

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AbstractMalnutrition is common in patients undergoing hemodialysis (HD) and is associated with mortality. This study aimed to investigate the association between changes in nutrition status measured by the Geriatric Nutritional Risk Index (GNRI) and all-cause mortality in patients who started HD. A nationwide retrospective cohort study was conducted based on the Korean Renal Data System database. Patients who started HD from January 2016 to December 2018, and were eligible for GNRI and GNRI trend were included. GNRI trend was a longitudinal change of GNRI, assessed by random slope in a mixed-e

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Huang, Ching-Ya, Wei-Ti Su, Ching-Hua Tsai, Shiun-Yuan Hsu, Ching-Hua Hsieh, and Cen-Hung Lin. "The Impact of Ideal Body Weight Estimation on Geriatric Nutritional Risk Index (GNRI) Classification and Outcomes in Elderly Trauma Care." Formosan Journal of Surgery, May 16, 2025. https://doi.org/10.1097/fs9.0000000000000229.

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Abstract Background Malnutrition is a critical concern among elderly trauma patients and is associated with poorer outcomes. The Geriatric Nutritional Risk Index (GNRI) is commonly used to assess nutritional risk in elderly patients; however, GNRI calculations depend on the ideal body weight (IBW) formula applied, which may vary significantly across populations. This study examines the impact of using different IBW formulas on GNRI classification and mortality prediction in elderly trauma patients. Methods We conducted a retrospective study on 2666 elderly trauma patients from the Trauma Regis

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