Academic literature on the topic 'Gonadotrophic hormone'

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Journal articles on the topic "Gonadotrophic hormone"

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Gracia-Navarro, F., and P. Licht. "Subcellular localization of gonadotrophic hormones LH and FSH in frog adenohypophysis using double-staining immunocytochemistry." Journal of Histochemistry & Cytochemistry 35, no. 7 (1987): 763–69. http://dx.doi.org/10.1177/35.7.3108366.

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We applied double post-embedding immunocytochemical methods using specific antibodies against bullfrog (Rana catesbeiana) luteinizing hormone (LH) and follicle-stimulating hormone (FSH) with immunogold staining (5- and 20-nm particles) to determine the subcellular localization of both gonadotropins and to observe their immunostaining patterns in anterior pituitary of the frog Rana pipiens. Results showed that individual gonadotrophs may store either one or both gonadotropins in a given secretory granule and in large globules (lysosomes?). Most gonadotrophs (50-88%) contain both hormones; 12-50
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Chopineau, M., N. Martinat, H. Marichatou, et al. "Evidence that the alpha-subunit influences the specificity of receptor binding of the equine gonadotrophins." Journal of Endocrinology 155, no. 2 (1997): 241–45. http://dx.doi.org/10.1677/joe.0.1550241.

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Horse LH/chorionic gonadotrophin (eLH/CG) exhibits, in addition to its normal LH activity, a high FSH activity in all other species tested. Donkey LH/CG (dkLH/CG) also exhibits FSH activity in other species, but about ten times less than the horse hormone. In order to understand the molecular basis of these dual gonadotrophic activities of eLH/CG and dkLH/CG better, we expressed, in COS-7 cells, hybrids between horse and donkey subunits, between horse or donkey alpha-subunit and human CG beta (hCG beta), and also between the porcine alpha-subunit and horse or donkey LH/CG beta. The resultant r
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Charlton, Harry. "Neural transplantation in hypogonadal (hpg) mice – physiology and neurobiology." Reproduction 127, no. 1 (2004): 3–12. http://dx.doi.org/10.1530/rep.1.00066.

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The hypogonadal (hpg) mouse mutant has a deletion in the region encoding the hypothalamic gonadotrophic hormone-releasing hormone decapeptide. As a consequence pituitary gonadotrophic hormone synthesis and release is severely curtailed and there is little or no post-natal gonadal development. Grafts of late fetal/early neonatal brain tissue containing the decapeptide-producing neurones into the third ventricle of hpg mice result, in a majority of animals, in a near normalisation of pituitary function with full spermatogenesis in male mice and full follicular and uterine development in females.
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Reznikov, A. G., N. D. Nosenko, E. N. Boris, L. I. Poliakova, P. V. Sinitsyn, and L. V. Tarasenko. "Evaluation of the efficacy of gonadotrophic inductors of ovulation in rats with hyperandrogenemia given flutamide." Problems of Endocrinology 57, no. 4 (2011): 28–31. http://dx.doi.org/10.14341/probl201157428-31.

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The objective of the present work was to study the influence of antiandrogen flutamide (flutapharm) at a dose of 1.0 mg/kg b.w., human chorionic gonadotropin (choragon, 5 IU), and folliculostimulating hormone (menopur, 0.01 IU) on the morphofunctional characteristics of ovaries. These products were administered either alone or sequentially to sexually mature female rats after the implantation of testosterone-containing polymeric capsules. The presence of hyperandogenism was confirmed by the five-fold rise in the blood testosterone levels. Analysis of the oestrus cycle, the weight and histologi
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Das, Nandana, and T. Rajendra Kumar. "Molecular regulation of follicle-stimulating hormone synthesis, secretion and action." Journal of Molecular Endocrinology 60, no. 3 (2018): R131—R155. http://dx.doi.org/10.1530/jme-17-0308.

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Follicle-stimulating hormone (FSH) plays fundamental roles in male and female fertility. FSH is a heterodimeric glycoprotein expressed by gonadotrophs in the anterior pituitary. The hormone-specific FSHβ-subunit is non-covalently associated with the common α-subunit that is also present in the luteinizing hormone (LH), another gonadotrophic hormone secreted by gonadotrophs and thyroid-stimulating hormone (TSH) secreted by thyrotrophs. Several decades of research led to the purification, structural characterization and physiological regulation of FSH in a variety of species including humans. Wi
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McDonald, William C., Nilanjana Banerji, Kelsey N. McDonald, Bridget Ho, Virgilia Macias, and Andre Kajdacsy-Balla. "Steroidogenic Factor 1, Pit-1, and Adrenocorticotropic Hormone: A Rational Starting Place for the Immunohistochemical Characterization of Pituitary Adenoma." Archives of Pathology & Laboratory Medicine 141, no. 1 (2016): 104–12. http://dx.doi.org/10.5858/arpa.2016-0082-oa.

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Context.—Pituitary adenoma classification is complex, and diagnostic strategies vary greatly from laboratory to laboratory. No optimal diagnostic algorithm has been defined. Objective.—To develop a panel of immunohistochemical (IHC) stains that provides the optimal combination of cost, accuracy, and ease of use. Design.—We examined 136 pituitary adenomas with stains of steroidogenic factor 1 (SF-1), Pit-1, anterior pituitary hormones, cytokeratin CAM5.2, and α subunit of human chorionic gonadotropin. Immunohistochemical staining was scored using the Allred system. Adenomas were assigned to a g
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Matson, Christine, and B. T. Donovan. "Acute effects of GnRF-induced gonadotrophin secretion upon ovarian steroid secretion in the ferret." Acta Endocrinologica 111, no. 3 (1986): 373–77. http://dx.doi.org/10.1530/acta.0.1110373.

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Abstract. The effects of an increase in endogenous gonadotrophin secretion on the production of oestradiol, progesterone, androstenedione and testosterone by the ovaries of anaesthetized anoestrous and oestrous ferrets were followed. Gonadotrophin secretion was enhanced by the injection of gonadotrophin releasing factor (GnRF), and serial blood samples were collected over 9 h for hormone assay. Thyrotrophic hormone releasing factor (TRF) or acetic acid were injected for control purposes. The plasma content of oestradiol in oestrous females was significantly higher than during anoestrus, but se
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Kanayama, K., H. Osada, and T. Endo. "Cleavage of Unfertilized Eggs after Repeated Administration of Human Chorionic Gonadotrophin to Hamsters." Journal of International Medical Research 25, no. 4 (1997): 202–5. http://dx.doi.org/10.1177/030006059702500405.

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The proportions of unfertilized eggs in the oviducts, showing abnormal cleavage, were examined in hamsters given single or repeated doses of 30 IU human gonadotrophic hormone for the induction of ovulation. In control animals ( n = 7), 1.7% of the total ovulated eggs were morphologically abnormal unfertilized eggs showing cleavage. The proportions of unfertilized eggs that were abnormal in the groups of seven hamsters treated with one, two or three doses of the gonadotrophin were 20.4%, 19.4%, and 30.4%, respectively. The proportion of unfertilized eggs showing abnormal cleavage thus appeared
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Tortonese, Domingo J., Susan J. Gregory, Rebecca C. Eagle, Carolyne L. Sneddon, Claire L. Young, and Julie Townsend. "The equine hypophysis: a gland for all seasons." Reproduction, Fertility and Development 13, no. 8 (2001): 591. http://dx.doi.org/10.1071/rd01066.

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The intrahypophysial mechanisms involved in the control of gonadotrophin secretion remain unclear. In the horse, a divergent pattern of gonadotrophins is observed at different stages of the reproductive cycle in response to a single secretagogue (gonadotrophin-releasing hormone), and dramatic changes in fertility take place throughout the year in response to photoperiod. This species thus provides a useful model to investigate the regulation of fertility directly at the level of the hypophysis. A series of studies were undertaken to examine the cytological arrangements and heterogeneity of gon
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Gründker, Carsten, and Günter Emons. "Role of Gonadotropin-Releasing Hormone (GnRH) in Ovarian Cancer." Cells 10, no. 2 (2021): 437. http://dx.doi.org/10.3390/cells10020437.

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The hypothalamus–pituitary–gonadal (HPG) axis is the endocrine regulation system that controls the woman’s cycle. The gonadotropin-releasing hormone (GnRH) plays the central role. In addition to the gonadotrophic cells of the pituitary, GnRH receptors are expressed in other reproductive organs, such as the ovary and in tumors originating from the ovary. In ovarian cancer, GnRH is involved in the regulation of proliferation and metastasis. The effects on ovarian tumors can be indirect or direct. GnRH acts indirectly via the HPG axis and directly via GnRH receptors on the surface of ovarian canc
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Dissertations / Theses on the topic "Gonadotrophic hormone"

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Gaudron, Sylvie-Marylène. "Environment endocrine pheromone relationships in the control of reproduction in the scale worm Harmothoë imbricata (Polychaeta: Polynoidae) (L.)". Thesis, University of Newcastle Upon Tyne, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289277.

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Wormald, Patricia J. "GnRH and neuropeptide regulation of gonadotropin secretion from cultured human pituitary cells." Doctoral thesis, University of Cape Town, 1988. http://hdl.handle.net/11427/27168.

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Gonadotropin-releasing hormone (GnRH) and its superactive analogues are currently being used in the treatment of a number of endocrine disorders, such as endometriosis, precocious puberty, infertility and prostatic cancer. Selection of these analogues for clinical use have been previously based on their activities in animal models. This thesis has therefore investigated the binding characteristics of the human GnRH receptor, in comparison to those of the rat receptor, as well as the activities of a number of GnRH analogues for stimulating luteinising hormone (LH) and follicle stimulating hormo
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Kirkpatrick, Bridgette Lee 1966. "Hormonal regulation of gonadotropin releasing hormone receptor expression in the ewe." Diss., The University of Arizona, 1998. http://hdl.handle.net/10150/282660.

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Endocrine regulation of expression of GnRH receptors is an important step in the control of reproduction. During the early follicular phase of the estrous cycle in the ewe, GnRH receptor expression increases in preparation for the preovulatory surge of LH. The studies described herein were designed to further elucidate the hormonal interactions controlling GnRH receptor expression. In long-term ovariectomized ewes, neither removal of progesterone, nor the presence of estradiol affected the expression of GnRH receptors. However, in ewes ovariectomized during the luteal phase of the estrous cycl
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Von, Boetticher S. "Investigating the mechanism of transcriptional regulation of the gonadotropin-releasing hormone receptor (GnRHR) gene by dexamethasone." Thesis, Link to the online version, 2008. http://hdl.handle.net/10019/1796.

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Powell, R. C. "Evolution of the structure and function of vertebrate brain gonadotropin-releasing hormone." Master's thesis, University of Cape Town, 1986. http://hdl.handle.net/11427/27201.

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In this study, the structure and function of gonadotropin-releasing hormone (GnRH) in different vertebrate species, in the classes Aves, Reptilia and Pisces was investigated. Acetic acid extracts were subjected to gel filtration chromatography and semipreparative high performance liquid chromatography (HPLC) to partially purify the GnRHs. The GnRH immunoreactivity was then characterized by analytical HPLC, and by assaying HPLC fractions by radioimmunoassay with region-specific antisera generated against mammalian GnRH, Gln⁸-GnRH and Trp⁷,Leu⁸-GnRH and assessing luteinizing hormone (LH)-releasi
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Armstrong, Stephen Paul. "Pulsatile Gonadotrophin-releasing Hormone Receptor Signalling." Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526055.

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李繼仁 and Kai-yan Lee. "Regulation of gonadotropin-releasing hormone and gonadotropin in goldfish, carassius auratus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1996. http://hub.hku.hk/bib/B31214332.

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Lee, Kai-yan. "Regulation of gonadotropin-releasing hormone and gonadotropin in goldfish, carassius auratus /." Hong Kong : University of Hong Kong, 1996. http://sunzi.lib.hku.hk/hkuto/record.jsp?B18038165.

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Flanagan, Colleen A. "Gonadotropin releasing hormone receptor ligand interactions." Doctoral thesis, University of Cape Town, 1995. http://hdl.handle.net/11427/27029.

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The decapeptide, gonadotropin releasing hormone (GnRH), is the central regulator of reproductive function. It binds to receptors on the gonadotrope cells of the pituitary and stimulates release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). Eleven different structural forms of GnRH have now been identified in various animal species. Chimaeric analogues of some of the variant forms of GnRH were synthesized in order to study the functional significance of the most common amino acid substitutions, which occur in positions 5, 7 and 8. Peptide binding affinities for sheep and r
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Gardner, Samantha. "Gonadotropin-releasing hormone targets Wnt signalling." Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/29112.

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This thesis describes a potential mechanism by which GnRH promotes the nuclear accumulation of β-catenin, activation of TCF-dependent transcription and up-regulation of Wnt target genes, c-Jun, Fra-1, Cyclin D1 and c-Mye. GnRH-induced nuclear accumulation of β-catenin and activation of β-catenin/TCF-dependent transcription was found to be dependent on a pathway utilising G<sub>q</sub>-Phospholipase C (PLC)-Diacylglycerol (DAG)/Protein kinase C (PKC), and was found to be specifically dependent on the PKC δ isoform. GnRH was found to mediate the inactivation of Glycogen Synthase Kinase-3 (GSK-3)
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Books on the topic "Gonadotrophic hormone"

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Jan, Horský. Gonadotropin-releasing hormone and ovarian function. Avicenum, Czechoslovak Medical Press, 1986.

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Organon Round Table Conference (3rd 1992 Paris, France). GnRH, GnRH analogs, gonadotropins, and gonadal peptides: The proceedings of the third Organon Round Table Conference, Paris, 1992. Parthenon Pub. Group, 1993.

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Saade, Georges. The regulation of luteinizing hormone and prolactin gene expression by gonadotrophin-releasing hormone and gonadal steroids in mice. University of Birmingham, 1988.

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World, Congress on Fertility and Sterility (15th 1995 Bologna Italy). Treatment with GnRH analogs: Controversies and perspectives : the proceedings of a satellite symposium of the 15th World Congress on Fertility and Sterility held in Bologna, Italy, 15-16 September 1995. Parthenon Pub. Group, 1996.

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Gore, Andrea C. GnRH, the master molecule of reproduction. Kluwer Academic Publishers, 2002.

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Gore, Andrea C. GnRH, the master molecule of reproduction. Kluwer Academic Publishers, 2002.

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Gore, Andrea C. GnRH, the master molecule of reproduction. Kluwer Academic Publishers, 2002.

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Elgendy, Manal. Minimising the dose of gonadotrophin releasing hormone agonist [GnRHa] and recombinant follicle stimulating hormone [FSH] used for controlled ovarian hyperstimulation in in-vitro fertilisation. University of Birmingham, 2001.

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Gillespie, Julia M. A. Melatonin mediated regulation of gonadotropin-releasing hormone (GnRH): Role of melatonin receptors and circadian rhythms. National Library of Canada, 2002.

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Ferring Symposium on Brain and Pituitary Peptides (3rd 1985 Noordwijk, Netherlands). Pulsatile GnRH 1985: Proceedings of the 3rd Ferring Symposium, Noordwijk, September 11-13, 1985. Edited by Coelingh Bennink, Herman Jan Tymen, 1943-. Ferring, 1985.

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Book chapters on the topic "Gonadotrophic hormone"

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Seth, John. "Gonadotrophin Releasing Hormone." In The Immunoassay Kit Directory. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-1414-1_24.

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Naor, Zvi, and Rony Seger. "Gonadotropin-Releasing Hormone." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_2477.

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Manji, Husseini K., Jorge Quiroz, R. Andrew Chambers, et al. "Gonadotropin-Releasing Hormone." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_1886.

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Naor, Zvi, and Rony Seger. "Gonadotropin-Releasing Hormone." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_2477-2.

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Naor, Zvi, and Rony Seger. "Gonadotropin-Releasing Hormone." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-46875-3_2477.

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de Roux, Nicolas, Beate Doeker, and Edwin Milgrom. "Gonadotropin and TSH Receptors." In Hormone Signaling. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4757-3600-7_10.

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Latronico, Ana Claudia, and Ivo Jorge Prado Arnhold. "Gonadotropin Resistance." In Hormone Resistance and Hypersensitivity. S. KARGER AG, 2013. http://dx.doi.org/10.1159/000342496.

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Helvacioglu, A. "Gonadotropin Releasing Hormone Treatment." In New Trends in Reproductive Medicine. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-60961-9_17.

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Colao, Annamaria, and Claudia Pivonello. "Gonadotropin Releasing Hormone (GnRH)." In Encyclopedia of Pathology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-28845-1_5110-1.

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Bidlingmaier, M. "Gonadotropin-Releasing-Hormon." In Springer Reference Medizin. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_1312.

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Conference papers on the topic "Gonadotrophic hormone"

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Liang, Zhe-Hao, and Wei Lu. "Prediction of the basic gonadotrophic hormone levels in girls with precocious puberty using ultrasonic union artificial neural network." In 2011 Seventh International Conference on Natural Computation (ICNC). IEEE, 2011. http://dx.doi.org/10.1109/icnc.2011.6022283.

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Ohlsson, M., A. J. W. Hsueh, and T. Ny. "HORMONE REGULATION OF THE FIBRINOLYTIC SYSTEM IN THE OVARY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644389.

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In the ovary, the release of oocytes from graafian follicles during hormone-induced ovulation has been found to be associated with substantial increases in follicular plasminogen activator (PA) activity. Most of the PA activity comes from the granulosa cells that have been shown to produce tPA, uPA as well as the type-1 PA-inhibitor,(PAI-1).We have studied the molecular mechanism of follicle stimulating hormone (FSH) and gonadotropin releasing hormone (GnRH) on the synthesis of tPA in primary cultures of rat granulosa cells. FSH and GnRH were both found to induce tPA in granulosa cells in a ti
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Hamad, Eyad M., Ghadeer Hawamdeh, Noor Abu Jarrad, Omar Yasin, Samer I. Al-Gharabli, and Raed Shadfan. "Detection of Human Chorionic Gonadotropin (hCG) Hormone using Digital Lateral Flow Immunoassay." In 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2018. http://dx.doi.org/10.1109/embc.2018.8513355.

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Sand, Sharon R., Catherine Klifa, Michael F. Press, et al. "Abstract 3557: Reduced ovarian hormones & reduced mammographic & MRI determined breast density inBRCAcarriers following a hormonal chemo-prevention regimen of gonadotropin releasing hormone agonist (GnRHA) & low-dose add-back estrogen & testosterone." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-3557.

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"TOWARDS A NEW HOMOGENEOUS IMMUNOASSAY FOR GONADOTROPIN-RELEASING HORMONE BASED ON TIME-RESOLVED FLUORESCENCE ANISOTROPY." In International Conference on Biomedical Electronics and Devices. SciTePress - Science and and Technology Publications, 2011. http://dx.doi.org/10.5220/0003152001840188.

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Pacucci, VA, F. Ceccarelli, G. Perrone, et al. "SAT0260 Ovarian function preservation with gonadotropin-releasing hormone analogues in patients with systemic lupus erythematosus treated with cyclophosphamide." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.6381.

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Asman, Aulia, Debby Sinthania, and Linda Marni. "The Effect of Epinephrine Administration on the Level of Gonadotropin Hormones of Japan Strain Female Mice (Mus Musculus)." In The Health Science International Conference. SCITEPRESS - Science and Technology Publications, 2019. http://dx.doi.org/10.5220/0009124301190123.

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Kim, HJ, MH Lee, JE Lee, et al. "Abstract P1-12-09: The oncologic effect of a gonadotropin releasing hormone (GnRH) agonist for ovarian protection during breast cancer chemotherapy." In Abstracts: Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium; December 8-12, 2015; San Antonio, TX. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.sabcs15-p1-12-09.

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Stepochkina, Anna, Andrey Bakhtyukov, Kira Derkach, Viktor Sorokoumov, Dmitry Dar’in, and Alexander Shpakov. "POTENTIAL EFFECT OF PRETREATMENT OF MALE RATS WITH TP03, AN ALLOSTERIC AGONIST OF LUTEINIZING HORMONE RECEPTOR, ON THE STEROIDOGENIC EFFECT OF GONADOTROPIN." In XVII INTERNATIONAL INTERDISCIPLINARY CONGRESS NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY. LCC MAKS Press, 2021. http://dx.doi.org/10.29003/m2338.sudak.ns2021-17/359-360.

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Yoon, TI, HJ Kim, JH Yu, et al. "Abstract P5-13-06: Concurrent gonadotropin-releasing hormone (GnRH) agonist administration with chemotherapy improves neoadjuvant chemotherapy responses in young premenopausal breast cancer patients." In Abstracts: Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium; December 8-12, 2015; San Antonio, TX. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.sabcs15-p5-13-06.

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