Log in

Relevant bibliographies by topics / Gonadotrophin secretion / Journal articles

To see the other types of publications on this topic, follow the link: Gonadotrophin secretion.

Journal articles on the topic 'Gonadotrophin secretion'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Gonadotrophin secretion.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Meeran, Dawud, Henryk F. Urbanski, Susan J. Gregory, Julie Townsend, and Domingo J. Tortonese. "Developmental Changes in the Hormonal Identity of Gonadotroph Cells in the Rhesus Monkey Pituitary Gland." Journal of Clinical Endocrinology & Metabolism 88, no. 6 (2003): 2934–42. http://dx.doi.org/10.1210/jc.2002-021001.

Full text

Abstract:

To help elucidate the regulatory mechanism responsible for divergent gonadotrophin secretion during sexual maturation, we examined the gonadotroph population and hormonal identity of gonadotroph subtypes in pituitary glands of juvenile (age, 1.7 ± 0.2 yr) and adult (age, 12.3 ± 0.8 yr) male rhesus monkeys (Macacca mulatta). Serum LH and testosterone concentrations were, respectively, 3 and 7 times lower in juveniles than in adults, thus confirming the different stages of development. Immunohistochemistry revealed that the proportion of LH gonadotrophs in relation to the total pituitary cell po

APA, Harvard, Vancouver, ISO, and other styles

2

Tortonese, Domingo J., Susan J. Gregory, Rebecca C. Eagle, Carolyne L. Sneddon, Claire L. Young, and Julie Townsend. "The equine hypophysis: a gland for all seasons." Reproduction, Fertility and Development 13, no. 8 (2001): 591. http://dx.doi.org/10.1071/rd01066.

Full text

Abstract:

The intrahypophysial mechanisms involved in the control of gonadotrophin secretion remain unclear. In the horse, a divergent pattern of gonadotrophins is observed at different stages of the reproductive cycle in response to a single secretagogue (gonadotrophin-releasing hormone), and dramatic changes in fertility take place throughout the year in response to photoperiod. This species thus provides a useful model to investigate the regulation of fertility directly at the level of the hypophysis. A series of studies were undertaken to examine the cytological arrangements and heterogeneity of gon

APA, Harvard, Vancouver, ISO, and other styles

3

Kereilwe, Onalenna, Kiran Pandey, Vitaliano Borromeo, and Hiroya Kadokawa. "Anti-Müllerian hormone receptor type 2 is expressed in gonadotrophs of postpubertal heifers to control gonadotrophin secretion." Reproduction, Fertility and Development 30, no. 9 (2018): 1192. http://dx.doi.org/10.1071/rd17377.

Full text

Abstract:

Preantral and small antral follicles may secret anti-Müllerian hormone (AMH) to control gonadotrophin secretion from ruminant gonadotrophs. The present study investigated whether the main receptor for AMH, AMH receptor type 2 (AMHR2), is expressed in gonadotrophs of postpubertal heifers to control gonadotrophin secretion. Expression of AMHR2 mRNA was detected in anterior pituitaries (APs) of postpubertal heifers using reverse transcription–polymerase chain reaction. An anti-AMHR2 chicken antibody was developed against the extracellular region near the N-terminus of bovine AMHR2. Western blotti

APA, Harvard, Vancouver, ISO, and other styles

4

Einspanier, A., and J. K. Hodges. "LH- and chorionic gonadotrophin-stimulated progesterone release in vitro by intact luteal tissue of the marmoset monkey (Callithrix jacchus)." Journal of Endocrinology 141, no. 3 (1994): 403–9. http://dx.doi.org/10.1677/joe.0.1410403.

Full text

Abstract:

Abstract The application of an in vitro microdialysis system (MDS) for studies on the gonadotrophic control of luteal progesterone secretion in the marmoset monkey is described. Luteal tissue collected from a total of six animals (9 ± 1 days after ovulation) was perfused with Ringer solution (without and with lipoprotein, 0·6 μg/ml). The tissue was exposed to repeated applications of human LH (hLH) and human chorionic gonadotrophin (hCG) (1, 10 and 100 IU/ml) each of 60 min duration. Perfusate was collected in 15-min fractions and assayed for progesterone content. Results showed that addition

APA, Harvard, Vancouver, ISO, and other styles

5

Rulli, Susana B., and Ilpo Huhtaniemi. "What have gonadotrophin overexpressing transgenic mice taught us about gonadal function?" Reproduction 130, no. 3 (2005): 283–91. http://dx.doi.org/10.1530/rep.1.00661.

Full text

Abstract:

The two gonadotrophins, follicle-stimulating hormone and luteinising hormone, are pivotal regulators of the development and maintenance of normal fertility by maintaining testicular and ovarian endocrine function and gametogenesis. Too low gonadotrophin secretion, i.e. hypogonadotrophic hypogonadism, is a common cause of infertility. But there are also physiological and pathophysiological conditions where gonadotrophin secretion and/or action are either transiently or chronically elevated, such as pregnancy, pituitary tumours, polycystic ovarian syndrome, activating gonadotrophin receptor muta

APA, Harvard, Vancouver, ISO, and other styles

6

Matson, Christine, and B. T. Donovan. "Acute effects of GnRF-induced gonadotrophin secretion upon ovarian steroid secretion in the ferret." Acta Endocrinologica 111, no. 3 (1986): 373–77. http://dx.doi.org/10.1530/acta.0.1110373.

Full text

Abstract:

Abstract. The effects of an increase in endogenous gonadotrophin secretion on the production of oestradiol, progesterone, androstenedione and testosterone by the ovaries of anaesthetized anoestrous and oestrous ferrets were followed. Gonadotrophin secretion was enhanced by the injection of gonadotrophin releasing factor (GnRF), and serial blood samples were collected over 9 h for hormone assay. Thyrotrophic hormone releasing factor (TRF) or acetic acid were injected for control purposes. The plasma content of oestradiol in oestrous females was significantly higher than during anoestrus, but se

APA, Harvard, Vancouver, ISO, and other styles

7

Daniels, M., P. Newland, J. Dunn, P. Kendall-Taylor, and M. C. White. "Long-term effects of a gonadotrophin-releasing hormone agonist ([d-Ser(But)6]GnRH(1–9)nonapeptide-ethylamide) on gonadotrophin secretion from human pituitary gonadotroph cell adenomas in vitro." Journal of Endocrinology 118, no. 3 (1988): 491–96. http://dx.doi.org/10.1677/joe.0.1180491.

Full text

Abstract:

ABSTRACT We have studied the effects of TRH and native gonadotrophin-releasing hormone (GnRH), and of a GnRH agonist (Buserelin; [d-Ser(But)6]GnRH(1–9) nonapeptide-ethylamide), on LH, FSH, α subunit and LH-β subunit secretion from three human gonadotrophin-secreting pituitary adenomas in dispersed cell culture. During a 24 h study, treatment with 276 nmol TRH/1 resulted in a significant (P < 0·05) stimulated release of FSH and α subunit from all three adenomas, and LH from the two adenomas secreting detectable concentrations of this glycoprotein; treatment with 85 nmol GnRH/l significantly

APA, Harvard, Vancouver, ISO, and other styles

8

Hanson, P. L., S. J. B. Aylwin, J. P. Monson, and J. M. Burrin. "FSH secretion predominates in vivo and in vitro in patients with non-functioning pituitary adenomas." European Journal of Endocrinology 152, no. 3 (2005): 363–70. http://dx.doi.org/10.1530/eje.1.01854.

Full text

Abstract:

Objective: Non-functioning pituitary adenomas (NFPAs) are characterised by the lack of symptoms of hormone hypersecretory syndromes but in vitro studies have demonstrated that tumour cells may stain for gonadotrophins and/or their α- or β-subunits. In this study, we aimed to examine the pattern of secretion of LH and FSH from a series of pituitary adenomas cultured in vitro and where data were available to relate the results to pre-operative serum gonadotrophin levels. Methods: The in vitro secretion of LH and FSH was measured from 46 cultured NFPAs and compared with pre-operative serum gonado

APA, Harvard, Vancouver, ISO, and other styles

9

Thomas, G. B., A. S. McNeilly, F. Gibson, and A. N. Brooks. "Effects of pituitary-gonadal suppression with a gonadotrophin-releasing hormone agonist on fetal gonadotrophin secretion, fetal gonadal development and maternal steroid secretion in the sheep." Journal of Endocrinology 141, no. 2 (1994): 317–24. http://dx.doi.org/10.1677/joe.0.1410317.

Full text

Abstract:

Abstract In order to investigate the regulation of the hypothalamo-pituitary-gonadal axis during fetal development, sheep fetuses at day 70 of gestation were implanted subcutaneously with a biodegradable implant containing the longacting gonadotrophin-releasing hormone (GnRH) agonist, buserelin. The treatment of fetuses with a GnRH agonist throughout the last half of gestation (term=145 days) abolished the increase in plasma LH concentrations that was seen in 2-day-old control lambs in response to an injection of GnRH. This attenuated response was associated with corresponding reductions in th

APA, Harvard, Vancouver, ISO, and other styles

10

Antonio, Leen, Maarten Albersen, Jaak Billen, et al. "Testicular Vein Sampling Can Reveal Gonadotropin-Independent Unilateral Steroidogenesis Supporting Spermatogenesis." Journal of the Endocrine Society 3, no. 10 (2019): 1881–86. http://dx.doi.org/10.1210/js.2019-00180.

Full text

Abstract:

Abstract Suppressed gonadotropins combined with high-normal serum testosterone concentrations in oligozoospermic men suggest either use of exogenous testosterone or presence of a testosterone-producing tumor. We describe the case of a 31-year-old man referred for primary infertility. Gonadotropins were undetectably low, but testosterone and estradiol were in the high-normal range. Semen analysis showed oligoasthenospermia. He denied using exogenous testosterone. Scrotal ultrasound showed microlithiasis and millimetric hypolucent lesions in the left testis but no intratesticular mass. Human cho

APA, Harvard, Vancouver, ISO, and other styles

11

Kereilwe, Onalenna, and Hiroya Kadokawa. "Bovine gonadotrophs express anti-Müllerian hormone (AMH): comparison of AMH mRNA and protein expression levels between old Holsteins and young and old Japanese Black females." Reproduction, Fertility and Development 31, no. 4 (2019): 810. http://dx.doi.org/10.1071/rd18341.

Full text

Abstract:

Anti-Müllerian hormone (AMH) is secreted from ovaries and stimulates gonadotrophin secretion from bovine gonadotroph cells. Other important hormones for endocrinological gonadotroph regulation (e.g. gonadotrophin-releasing hormone, inhibin and activin) have paracrine and autocrine roles. Therefore, in this study, AMH expression in bovine gonadotroph cells and the relationships between AMH expression in the bovine anterior pituitary (AP) and oestrous stage, age and breed were evaluated. AMH mRNA expression was detected in APs of postpubertal heifers (26 months old) by reverse transcription-poly

APA, Harvard, Vancouver, ISO, and other styles

12

Miller, D. W., and A. N. Brooks. "Placental steroids are involved in the late-gestation decrease in gonadotrophin secretion in the ovine fetus." Proceedings of the British Society of Animal Science 1999 (1999): 66. http://dx.doi.org/10.1017/s1752756200002210.

Full text

Abstract:

The mid-gestation peak in activity of the fetal gonadotrophic axis is thought to be crucial for normal reproductive development. It is clear that the increase to mid-gestation is a result of the concomitant rise in gonadotrophs (Thomas et al., 1993). The mechanisms responsible for the decrease after mid-gestation are unclear, but may involve feedback from the placental steroids (Challis et al., 1981; Gluckman et al., 1983). The aim was to determine the roles of the placental steroids, progesterone and oestradiol, in the late-gestation decline in fetal gonadotrophins using the oestradiol antago

APA, Harvard, Vancouver, ISO, and other styles

13

Johnson, M. S., R. Mitchell, and G. Fink. "The role of protein kinase C in LHRH-induced LH and FSH release and LHRH self-priming in rat anterior pituitary glands in vitro." Journal of Endocrinology 116, no. 2 (1988): 231–39. http://dx.doi.org/10.1677/joe.0.1160231.

Full text

Abstract:

ABSTRACT We have investigated the role of protein kinase C (PKC) in LHRH-induced LH and FSH secretion and LHRH priming. Hemipituitary glands from pro-oestrous rats were incubated with agents known to affect PKC and with or without LHRH, during which time the secretion of gonadotrophins was measured. Phorbol esters and phospholipase C, activators of PKC, released LH and FSH in a concentration-dependent manner and potentiated the LHRH-induced secretion of gonadotrophins in parallel with their ability to release these hormones alone. Inhibitors of PKC had either no effect on LH release (1-(5-isoq

APA, Harvard, Vancouver, ISO, and other styles

14

Nangalama, A. W., and G. P. Moberg. "Interaction between cortisol and arachidonic acid on the secretion of LH from ovine pituitary tissue." Journal of Endocrinology 131, no. 1 (1991): 87–94. http://dx.doi.org/10.1677/joe.0.1310087.

Full text

Abstract:

ABSTRACT In several species, glucocorticoids act directly on the pituitary gonadotroph to suppress the gonadotrophin-releasing hormone (GnRH)-induced secretion of the gonadotrophins, especially LH. A mechanism for this action of these adrenal steroids has not been established, but it appears that the glucocorticoids influence LH release by acting on one or more post-receptor sites. This study investigated whether glucocorticoids disrupt GnRH-induced LH release by altering the liberation of arachidonic acid from plasma membrane phospholipids, a component of GnRH-induced LH release. Using perifu

APA, Harvard, Vancouver, ISO, and other styles

15

Ludwig, K. "Molecular mechanisms of gonadotrophin releasing hormone-stimulated gonadotrophin secretion." Human Reproduction 8, suppl 2 (1993): 23–28. http://dx.doi.org/10.1093/humrep/8.suppl_2.23.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Anderson, L. "Intracellular mechanisms triggering gonadotrophin secretion." Reviews of Reproduction 1, no. 3 (1996): 193–202. http://dx.doi.org/10.1530/revreprod/1.3.193.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Anderson, L. "Intracellular mechanisms triggering gonadotrophin secretion." Reviews of Reproduction 1, no. 3 (1996): 193–202. http://dx.doi.org/10.1530/ror.0.0010193.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Tsatsoulla, A., S. M. Shalet, and W. R. Robertson. "Bioactive gonadotrophin secretion in man." Clinical Endocrinology 35, no. 3 (1991): 193–206. http://dx.doi.org/10.1111/j.1365-2265.1991.tb03522.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Khurshid, S., G. F. Weinbauer, and E. Nieschlag. "Effects of administration of testosterone and gonadotrophin-releasing hormone (GnRH) antagonist on basal and GnRH-stimulated gonadotrophin secretion in orchidectomized monkeys." Journal of Endocrinology 129, no. 3 (1991): 363–70. http://dx.doi.org/10.1677/joe.0.1290363.

Full text

Abstract:

ABSTRACT The aim of the present investigation was to investigate the effects of testosterone on basal and gonadotrophin-releasing hormone (GnRH)-stimulated gonadotrophin secretion in the presence and absence of a GnRH antagonist in a non-human primate model (Macaca fascicularis). Orchidectomized animals were used in order to avoid interference by testicular products other than testosterone involved in gonadotrophin feedback. Concomitant and delayed administration of testosterone at doses that provided serum levels either within the intact range (study 1) or markedly above that range (study 2)

APA, Harvard, Vancouver, ISO, and other styles

20

Lapcik, O., A. Perheentupa, M. Bicikova, I. Huhtaniemi, R. Hampl, and L. Starka. "The effect of epitestosterone on gonadotrophin synthesis and secretion." Journal of Endocrinology 143, no. 2 (1994): 353–58. http://dx.doi.org/10.1677/joe.0.1430353.

Full text

Abstract:

Abstract The effects of 3-week treatment with increasing doses of epitestosterone (ET) on gonadotrophin gene expression and secretion, on testosterone and 5α-dihydrotestosterone (DHT) levels, and on the weight of testes and prostates, were studied in intact adult male rats. The hormones were delivered by means of silastic capsules of different lengths filled with the steroid. One group of rats received testosterone (T) instead of ET, to compare the results with previous studies concerning the testosterone effect. The controls were given capsules with glucose only. Treatment with ET, as well as

APA, Harvard, Vancouver, ISO, and other styles

21

Pinilla, L., P. Garnelo, M. Tena-Sempere, F. Gaytan, and E. Aguilar. "Mechanisms of reproductive deficiency in male rats treated neonatally with a gonadotrophin-releasing hormone antagonist." Journal of Endocrinology 142, no. 3 (1994): 517–25. http://dx.doi.org/10.1677/joe.0.1420517.

Full text

Abstract:

Abstract It is well known that males injected neonatally with oestradiol or antiserum or antagonists (ANT) against gonadotrophin-releasing hormone (GnRH) show multiple reproductive disorders. In the present work, in males treated neonatally with GnRH-ANT, we have analysed: (1) whether the impairment of reproductive function can be blocked by simultaneous treatment with gonadotrophins, (2) the possible differences in the effects of GnRH-ANT injected before or after the proliferation of Sertoli cells which takes place between days 1 and 15 of age, and (3) the mechanism(s) for the increased FSH s

APA, Harvard, Vancouver, ISO, and other styles

22

Miller, D. W., D. Blache, and G. B. Martin. "The role of intracerebral insulin in the effect of nutrition on gonadotrophin secretion in mature male sheep." Journal of Endocrinology 147, no. 2 (1995): 321–29. http://dx.doi.org/10.1677/joe.0.1470321.

Full text

Abstract:

Abstract The effect of nutrition on gonadotrophin secretion may be exerted through a central metabolic signal that reflects nutritional status. We have previously found that glucose and insulin concentrations are elevated in the cerebrospinal fluid (CSF) of rams in which the secretion of gonadotrophins has been stimulated by a nutritional supplement of lupin grain (Lupinus angustifolius). In the present study, we tested the hypothesis that insulin and/or glucose is a metabolic modulator of GnRH secretion and mediates the effects of nutrition on gonadotrophin secretion. Six mature rams were fed

APA, Harvard, Vancouver, ISO, and other styles

23

Nagahara, Yasuhito, Akira Miyake, Keiichi Tasaka, Yasuhiro Kawamura, Toshihiro Aono, and Osamu Tanizawa. "Possible site of negative and positive feedback action of oestrogen on gonadotrophin secretion in normal women." Acta Endocrinologica 108, no. 4 (1985): 440–44. http://dx.doi.org/10.1530/acta.0.1080440.

Full text

Abstract:

Abstract. For determination of the site of action of oestrogen (E) during the negative and positive feedback phases of gonadotrophin secretions, studies were made on the pituitary response to a small amount of LRH and the pulsatility of gonadotrophins after E administration in normal cycling women in the mid-follicular phase. The pituitary responses to an iv bolus of 2.5 μg of synthetic LRH were evaluated by measuring serum LH and FSH 2 h before and 8 h after administration of 20 mg of conjugated E (Premarin). In the next cycle, the pituitary responses to a same dose of LRH were also observed

APA, Harvard, Vancouver, ISO, and other styles

24

Bergendahl, M., and I. Huhtaniemi. "The time since castration influences the effects of short-term starvation on gonadotrophin secretion in male rats." Journal of Endocrinology 143, no. 2 (1994): 209–19. http://dx.doi.org/10.1677/joe.0.1430209.

Full text

Abstract:

Abstract Short-term starvation suppresses the pituitary-testicular function in rats, evidently through inhibition of gonadotrophin-releasing hormone (GnRH) release. However, when gonadotrophin secretion is strongly enhanced, e.g. after castration, starvation does not suppress gonadotrophins. To test whether the time since castration affects the pituitary response to starvation, adult male rats were totally deprived of food for five days (only water allowed) immediately (acute castration) or two weeks after castration (chronic castration). The pituitary contents of GnRH receptors were decreased

APA, Harvard, Vancouver, ISO, and other styles

25

Clayton, R. N., A. Detta, S. I. Naik, L. S. Young, and H. M. Charlton. "Gonadotrophin releasing hormone receptor regulation in relationship to gonadotrophin secretion." Journal of Steroid Biochemistry 23, no. 5 (1985): 691–702. http://dx.doi.org/10.1016/s0022-4731(85)80004-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Kuhn, Jean Marc, Lise Duranteau, Max A. Rieu, Najiba Lahlou, Marc Roger, and Jean Pierre Luton. "Evidence of oestradiol-induced changes in gonadotrophin secretion in men with feminizing Leydig cell tumours." European Journal of Endocrinology 131, no. 2 (1994): 160–66. http://dx.doi.org/10.1530/eje.0.1310160.

Full text

Abstract:

Kuhn JM, Duranteau L, Rieu MA, Lahlou N, Roger M, Luton JP. Evidence of oestradiol-induced changes in gonadotrophin secretion in men with feminizing Leydig cell tumours. Eur J Endocrinol 1994;131:160–6. ISSN 0804–4643 To study the sex steroid-gonadotrophin relationship, plasma oestradiol (E2), testosterone and gonadotrophin-releasing hormone (GnRH)-induced (100 μg iv) gonadotrophin response were measured in 42 male partners of infertile couples with normal sperm count (group I) and in 21 men with Leydig cell tumour (LCT, group II) in which a basal evaluation was repeated after tumour removal.

APA, Harvard, Vancouver, ISO, and other styles

27

Evans, J. J., and K. J. Catt. "Gonadotrophin-releasing activity of neurohypophysial hormones: II. The pituitary oxytocin receptor mediating gonadotrophin release differs from that of corticotrophs." Journal of Endocrinology 122, no. 1 (1989): 107–16. http://dx.doi.org/10.1677/joe.0.1220107.

Full text

Abstract:

ABSTRACT Neurohypophysial hormones stimulate gonadotrophin release from dispersed rat anterior pituitary cells in vitro, acting through receptors distinct from those which mediate the secretory response to gonadotrophin-releasing hormone (GnRH). The LH response to oxytocin was not affected by the presence of the phosphodiesterase inhibitor, methyl isobutylxanthine, but was diminished in the absence of extracellular calcium and was progressively increased as the calcium concentration in the medium was raised to normal. In addition, the calcium channel antagonist, nifedipine, suppressed oxytocin

APA, Harvard, Vancouver, ISO, and other styles

28

Beindorff, Nicola, and Almuth Einspanier. "Luteotrophic effects of relaxin, chorionic gonadotrophin and FSH in common marmoset monkeys (Callithrix jacchus)." REPRODUCTION 139, no. 5 (2010): 923–30. http://dx.doi.org/10.1530/rep-09-0257.

Full text

Abstract:

In early pregnant primates, relaxin (RLX) is highly upregulated within the corpus luteum (CL), suggesting that RLX may have an important role in the implantation of the blastocyst. Therefore, the aim of the present study was to investigate the local effects of RLX and gonadotrophins on the maintenance of the CL using anin vitromicrodialysis system. CLs of common marmoset monkeys were collected by luteectomy during different stages of the luteal phase and early pregnancy. Each CL was perfused with either Ringer's solution alone or Ringer's solution supplemented with either porcine RLX (250, 500

APA, Harvard, Vancouver, ISO, and other styles

29

Lopata, A., and K. Oliva. "Chorionic gonadotrophin secretion by human blastocysts." Human Reproduction 8, no. 6 (1993): 932–38. http://dx.doi.org/10.1093/oxfordjournals.humrep.a138170.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

López-Calderón, A., M. I. Gonzaléz-Quijano, J. A. F. Tresguerres, and C. Ariznavarreta. "Role of LHRH in the gonadotrophin response to restraint stress in intact male rats." Journal of Endocrinology 124, no. 2 (1990): 241–46. http://dx.doi.org/10.1677/joe.0.1240241.

Full text

Abstract:

ABSTRACT A hypothalamic site of action has been hypothesized for the inhibitory effect of chronic stress on gonadotrophin secretion. The aim of the present study was to examine the temporal changes in hypothalamic LHRH content and gonadotrophin secretion during restraint stress, and the pituitary responsiveness to LHRH stimulation in chronically stressed rats. Adult male rats were killed after being restrained for 0, 20, 45, 90, 180 and 360 min or for 6 h daily over 2, 3 and 4 days. After 20–45 min of stress there was an increase in plasma concentrations of LH (P<0·01) and a decrease in hyp

APA, Harvard, Vancouver, ISO, and other styles

31

Farnworth, P. G. "Gonadotrophin secretion revisited. How many ways can FSH leave a gonadotroph?" Journal of Endocrinology 145, no. 3 (1995): 387–95. http://dx.doi.org/10.1677/joe.0.1450387.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Tomasi, Paolo A., Giuseppe Fanciulli, Michele Zini, Maria A. Demontis, Alessandra Dettori, and Giuseppe Delitala. "Pulsatile gonadotrophin secretion in hypothyroid women of reproductive age." European Journal of Endocrinology 136, no. 4 (1997): 406–9. http://dx.doi.org/10.1530/eje.0.1360406.

Full text

Abstract:

Abstract Hypothyroid women may have various disturbances of the reproductive system. Although menstrual cycle disturbances and infertility have been reported in hypothyroidism, gonadotrophin levels have usually been found in the normal range. We have investigated whether female hypothyroid patients of reproductive age have any alteration in the pulsatile secretory pattern of gonadotrophin secretion. LH and FSH were assayed on days 2–5 of the menstrual cycle in blood samples taken every 10 min for 8 h from six hypothyroid women and six age-matched control subjects. Pulsatility was analysed usin

APA, Harvard, Vancouver, ISO, and other styles

33

Angervo, M., R. Koistinen, and M. Seppälä. "Epidermal growth factor stimulates production of insulin-like growth factor-binding protein-1 in human granulosa-luteal cells." Journal of Endocrinology 134, no. 1 (1992): 127–31. http://dx.doi.org/10.1677/joe.0.1340127.

Full text

Abstract:

ABSTRACT Insulin-like growth factor-I (IGF-I) enhances and epidermal growth factor (EGF) inhibits gonadotrophin-induced aromatization in granulosa cells. Our previous studies have shown that human ovarian granulosa cells synthesize insulin-like growth factor-binding protein-1 (IGFBP-1) which inhibits IGF-stimulated DNA synthesis. The present study addresses the effect of EGF and gonadotrophins in the regulation of IGFBP-1 release by human granulosa cells cultured in serum-free medium. At concentrations of 1–100 μg/l EGF was found to stimulate IGFBP-1 secretion. This was not due to cell prolife

APA, Harvard, Vancouver, ISO, and other styles

34

Evans, J. J., G. Robinson, and K. J. Catt. "Gonadotrophin-releasing activity of neurohypophysial hormones: I. Potential for modulation of pituitary hormone secretion in rats." Journal of Endocrinology 122, no. 1 (1989): 99–106. http://dx.doi.org/10.1677/joe.0.1220099.

Full text

Abstract:

ABSTRACT Neurohypophysial hormones have been implicated in the control of anterior pituitary function, and oxytocin has been shown to stimulate gonadotrophin excretion and ovarian follicular development in certain species. To determine the role of neurohypophysial peptides in the control of gonadotrophin release, their actions on LH and FSH secretion were analysed in rats in vivo and in vitro. In adult female rats, administration of oxytocin during early pro-oestrus advanced the spontaneous LH surge and markedly increased peripheral LH levels at 15.00 h compared with control animals. In cultur

APA, Harvard, Vancouver, ISO, and other styles

35

Birnie, L. M., P. J. Broadbent, J. S. M. Hutchinson, R. G. Watt, and D. F. Dolman. "Effects of gonadotrophin releasing hormone agonist treatment on oestrous cycle length and superovulatory response in maiden heifers." Proceedings of the British Society of Animal Science 1995 (March 1995): 141. http://dx.doi.org/10.1017/s030822960002907x.

Full text

Abstract:

Current variability in superovulatory response prevents the economical production of large numbers of high quality embryos and limits the use of embryo transfer. Pulsatile administration of GnRH (gonadotrophin releasing hormone) elicits pulsatile secretion of LH (luteinising hormone) while chronic treatment with a potent GnRH agonist reduces LH secretion. Using the latter, gonadotrophin-dependent preovulatory antral follicle development may be suppressed, resulting in a uniform cohort of small antral follicles in the absence of a dominant follicle which could then be superstimulated by exogeno

APA, Harvard, Vancouver, ISO, and other styles

36

Crawford, J. L., D. A. Heath, L. J. Haydon, B. P. Thomson, and D. C. Eckery. "Gene expression and secretion of LH and FSH in relation to gene expression of GnRH receptors in the brushtail possum (Trichosurus vulpecula) demonstrates highly conserved mechanisms." REPRODUCTION 137, no. 1 (2009): 129–40. http://dx.doi.org/10.1530/rep-08-0347.

Full text

Abstract:

In eutherian mammals, the gonadotrophins (LH and FSH) are synthesized and stored in gonadotroph cells under the regulation of multiple mechanisms including GnRH. Very little is known about the regulation of gonadotrophin secretion and storage in pituitary glands of marsupials. This study revealed, using quantitative PCR and heterologous RIA techniques, thatLHBmRNA expression levels remained constant over the oestrous cycle, regardless of the presence of a preovulatory LH surge, which is characteristic of a hormone secreted under regulation. Our sampling regime was unable to detect pulses of LH

APA, Harvard, Vancouver, ISO, and other styles

37

Dalkin, A. C., S. J. Paul, D. J. Haisenleder, G. A. Ortolano, M. Yasin, and J. C. Marshall. "Gonadal steroids effect similar regulation of gonadotrophin subunit mRNA expression in both male and female rats." Journal of Endocrinology 132, no. 1 (1992): 39–45. http://dx.doi.org/10.1677/joe.0.1320039.

Full text

Abstract:

ABSTRACT Gonadal steroids can act both indirectly via gonadotrophin-releasing hormone (GnRH) and directly on the pituitary to regulate gonadotrophin subunit gene expression. Recent studies to assess a possible direct action at the pituitary have shown that testosterone, when given to males in the absence of endogenous GnRH action, selectively increases FSH-β mRNA concentrations. Conversely, in females, oestradiol appears to regulate gonadotrophin subunit mRNAs primarily via GnRH. The present study was designed to determine whether these differing results reflect specific actions of the gonadal

APA, Harvard, Vancouver, ISO, and other styles

38

Dada, M. O., and C. A. Blake. "Monosodium l-glutamate administration: effects on gonadotrophin secretion, gonadotrophs and mammotrophs in prepubertal female rats." Journal of Endocrinology 104, no. 2 (1985): 185—NP. http://dx.doi.org/10.1677/joe.0.1040185.

Full text

Abstract:

ABSTRACT We have studied gonadotrophin secretion and immunocytochemically stained gonadotrophs and mammotrophs in 35-day-old female rats which had been treated with monosodium glutamate (MSG) as neonates. We also compared our morphometric data in the saline-treated controls with those we have previously obtained in normal adult female rats. The size of the anterior pituitary glands was reduced but the serum levels, the pituitary gland concentrations and contents, and the in-vitro basal release rates of LH and FSH were not significantly altered by MSG treatment. The size of the LH and FSH cells

APA, Harvard, Vancouver, ISO, and other styles

39

Evans, A. C. O., and N. C. Rawlings. "Effects of a long-acting gonadotrophin-releasing hormone agonist (Leuprolide) on ovarian follicular development in prepubertal heifer calves." Canadian Journal of Animal Science 74, no. 4 (1994): 649–56. http://dx.doi.org/10.4141/cjas94-094.

Full text

Abstract:

We studied the effects of reducing gonadotrophin secretion on ovarian follicular development in young prepubertal heifer calves. Calves received a GnRH agonist (n = 5, 15 mg of Leuprolide acetate, i.m.) or carrier (n = 5) at 8 and 12 w of age. Starting at 8 and 34 w of age, ovarian follicles were monitored daily for 17 d, and at 10, 15, 25 and 35 w of age, blood samples were collected every 15 min for 12 h for measurement of serum concentration of LH and FSH. GnRH agonist treatment did not affect the age and body weight at puberty (P > 0.05). Agonist treatment suppressed follicle numbers an

APA, Harvard, Vancouver, ISO, and other styles

40

Nicol, L., M.-O. Faure, J. R. McNeilly, J. Fontaine, C. Taragnat та A. S. McNeilly. "Bone morphogenetic protein-4 interacts with activin and GnRH to modulate gonadotrophin secretion in LβT2 gonadotrophs". Journal of Endocrinology 196, № 3 (2008): 497–507. http://dx.doi.org/10.1677/joe-07-0542.

Full text

Abstract:

We have shown previously that, in sheep primary pituitary cells, bone morphogenetic proteins (BMP)-4 inhibits FSHβ mRNA expression and FSH release. In contrast, in mouse LβT2 gonadotrophs, others have shown a stimulatory effect of BMPs on basal or activin-stimulated FSHβ promoter-driven transcription. As a species comparison with our previous results, we used LβT2 cells to investigate the effects of BMP-4 on gonadotrophin mRNA and secretion modulated by activin and GnRH. BMP-4 alone had no effect on FSH production, but enhanced the activin+GnRH-induced stimulation of FSHβ mRNA and FSH secretio

APA, Harvard, Vancouver, ISO, and other styles

41

Irvine, C. H. G., and S. L. Alexander. "Secretion rates and short-term patterns of gonadotrophin-releasing hormone, FSH and LH in the normal stallion in the breeding season." Journal of Endocrinology 117, no. 2 (1988): 197–206. http://dx.doi.org/10.1677/joe.0.1170197.

Full text

Abstract:

ABSTRACT Pituitary venous blood was collected by a painless non-surgical cannulation method from five ambulatory stallions at 5-min intervals for 5–6 h during the breeding season. In four adult stallions, statistical analysis showed that pulses of gonadotrophin-releasing hormone (GnRH) and LH were coincident (P <0·01), as were pulses of FSH and LH (P <0·05). Furthermore, the patterns of changes in concentration of FSH and LH were highly correlated in each of the four stallions. However, seemingly ineffective pulses of GnRH were also observed, with 28% of GnRH pulses failing to induce a s

APA, Harvard, Vancouver, ISO, and other styles

42

McNeilly, A. S. "Prolactin and the control of gonadotrophin secretion." Journal of Endocrinology 115, no. 1 (1987): 1–5. http://dx.doi.org/10.1677/joe.0.1150001.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

WAAL, H. A. DELEMARRE-VAN, J. M. B. WENNINK, and R. J. H. ODINK. "Gonadotrophin and Growth Hormone Secretion Throughout Puberty." Acta Paediatrica 80, s372 (1991): 26–31. http://dx.doi.org/10.1111/j.1651-2227.1991.tb17964.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Dedes, Ioannis. "Kisspeptins and the control of gonadotrophin secretion." Systems Biology in Reproductive Medicine 58, no. 3 (2012): 121–28. http://dx.doi.org/10.3109/19396368.2011.651555.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Genazzani, A. R., A. D. Genazzani, C. Volpogni, et al. "Opioid control of gonadotrophin secretion in humans." Human Reproduction 8, suppl 2 (1993): 151–53. http://dx.doi.org/10.1093/humrep/8.suppl_2.151.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Fingscheidt, U., GF Weinbauer, HL Fehm, and E. Nieschlag. "Regulation of gonadotrophin secretion by inhibin, testosterone and gonadotrophin-releasing hormone in pituitary cell cultures of male monkeys." Journal of Endocrinology 159, no. 1 (1998): 103–10. http://dx.doi.org/10.1677/joe.0.1590103.

Full text

Abstract:

The effects of bovine inhibin, testosterone and GnRH on gonadotrophin secretion by primate pituitary cells were characterized in vitro using pituitaries from six male rhesus monkeys and one male cynomolgus monkey. The effect of inhibin on basal secretion of FSH and LH was investigated. Dose-response curves in monkeys and rats were compared. GnRH dose-response curves in the presence and absence of testosterone were also examined in monkeys. In monkey pituitary cells, testosterone at a concentration of 10(-7) M had no effect on LH or FSH secretion. Inhibin suppressed FSH secretion to 50.8% of th

APA, Harvard, Vancouver, ISO, and other styles

47

Naik, S. I., G. Saade, A. Detta, and R. N. Clayton. "Homologous ligand regulation of gonadotrophin-releasing hormone receptors in vivo: relationship to gonadotrophin secretion and gonadal steroids." Journal of Endocrinology 107, no. 1 (1985): 41–47. http://dx.doi.org/10.1677/joe.0.1070041.

Full text

Abstract:

ABSTRACT A single injection of gonadotrophin-releasing hormone (GnRH) (60 ng s.c., 42·9 nmol) induced biphasic GnRH receptor regulation in normal intact adult female mice. A transient 22% receptor decrease occurred 30–60 min after injection of GnRH when peak serum decapeptide concentrations were reached (137 ± 41 (s.e.m.) ng/l). This GnRH receptor decrease occurred shortly after the peak serum LH values at 15–30 min. The subsequent rapid (within 1 h) return of GnRH receptor levels to normal suggested transient receptor occupancy by GnRH rather than true receptor loss. At 8 h after injection of

APA, Harvard, Vancouver, ISO, and other styles

48

Hearn, J. P., J. K. Hodges, and S. Gems. "Early secretion of chorionic gonadotrophin by marmoset embryos in vivo and in vitro." Journal of Endocrinology 119, no. 2 (1988): 249–55. http://dx.doi.org/10.1677/joe.0.1190249.

Full text

Abstract:

ABSTRACT The control mechanisms of early pregnancy in primates differ from those in non-primate species in the early secretion of chorionic gonadotrophin (CG) by the embryo and in the support of the corpus luteum. This study describes the initiation of secretion of CG by the embryo of the marmoset monkey examined in vivo and in vitro. A bioassay for gonadotrophin, which did not distinguish between CG and LH, was adapted and validated for the marmoset. A system of embryo culture was developed whereby embryos were grown from morula/blastocyst stages until at least the differentiation of the trop

APA, Harvard, Vancouver, ISO, and other styles

49

Knight, P. G., and R. J. Castillo. "Effects of bovine follicular fluid on gonadotrophin secretion in intact and chronically ovariectomized ewes before and after desensitization of pituitary gonadotrophs to gonadotrophin-releasing hormone." Journal of Endocrinology 117, no. 3 (1988): 431–39. http://dx.doi.org/10.1677/joe.0.1170431.

Full text

Abstract:

ABSTRACT Intact and chronically ovariectomized ewes were treated for 4 days with charcoal-treated bovine follicular fluid (FF) or charcoal-treated bovine serum during the late-anoestrous period, and the effects on basal and gonadotrophin-releasing hormone (GnRH)-induced secretion of LH and FSH observed. Subsequently, ewes received s.c. implants containing a sustained-release formulation of a potent GnRH agonist d-Ser(But)6-Azgly10-LHRH (ICI 118630) to desensitize pituitary gonadotrophs to hypothalamic stimulation, and the effects of bovine FF and bovine serum were re-assessed 2 weeks later. Ch

APA, Harvard, Vancouver, ISO, and other styles

50

SAUDER, S. E., M. S. FRAGER, G. D. CASE, R. P. KELCH, and J. C. MARSHALL. "EFFECTS OF CHANGING GONADOTROPHIN-RELEASING HORMONE PULSE FREQUENCY ON GONADOTROPHIN SECRETION IN MEN." Clinical Endocrinology 28, no. 6 (1988): 647–56. http://dx.doi.org/10.1111/j.1365-2265.1988.tb03857.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!