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Relevant bibliographies by topics / Gonadotropins and castration

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Academic literature on the topic 'Gonadotropins and castration'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Gonadotropins and castration"

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Balasinor, Nafisa, Manjit K. Gill-Sharma, Priyanka Parte, and HS Juneja. "Cerebrospinal fluid and blood concentrations of luteinizing hormone, follicle stimulating hormone and prolactin following castration of adult male rats." Acta Endocrinologica 127, no. 1 (1992): 58–65. http://dx.doi.org/10.1530/acta.0.1270058.

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Comparative levels of LH, FSH and PRL in the serum and cerebrospinal fluid (CSF) of adult male rats were studied at different periods following castration. Intact and sham-operated animals served as controls. Blood and CSF were collected at 1, 3, 7, 14, 21, 28, 35 and 46 days following castration. The CSF was collected via cisterna-magna puncture, while the blood was collected from abdominal aorta. Serum gonadotropins increased progressively beginning day 1 post-castration to reach maximum by day 35 or 46 post-castration. Sham operation and castration did not affect mean CSF, LH and FSH levels

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Kochman, Kazimierz, and Alina Gajewska. "Biosynthesis of gonadotropins in vivo." Acta Neurobiologiae Experimentalis 56, no. 3 (1996): 753–56. http://dx.doi.org/10.55782/ane-1996-1180.

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GnRH is potent stimulator of gonadotropin's alpha and beta chains synthesis in vivo. Stimulation of LHbeta gene transcription requires pulsatile GnRH administration but the transcription of alpha subunit can be stimulated independently of GnRH mode of administration. Castration increases whereas in vivo estradiol and testosterone replacement decreases the rate of gene transcription of pituitary gonadotropin subunits. Thyroid hormones can enhance or diminish the pituitary levels of LHbeta and FSHbeta subunit mRNAs in female rats. Inhibin, activin and follistatin were shown to be potent regulato

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Bowen, Richard L., Giuseppe Verdile, Tianbing Liu та ін. "Luteinizing Hormone, a Reproductive Regulator That Modulates the Processing of Amyloid-β Precursor Protein and Amyloid-β Deposition". Journal of Biological Chemistry 279, № 19 (2004): 20539–45. http://dx.doi.org/10.1074/jbc.m311993200.

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Hormonal changes associated with the dysregulation of the hypothalamic-pituitary-gonadal (HPG) axis following menopause/andropause have been implicated in the pathogenesis of Alzheimer's disease (AD). Experimental support for this has come from studies demonstrating an increase in amyloid-β (Aβ) deposition following ovariectomy/castration. Because sex steroids and gonadotropins are both part of the HPG feedback loop, any loss in sex steroids results in a proportionate increase in gonadotropins. To assess whether Aβ generation was due to the loss of serum 17β-estradiol or to the up-regulation o

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KENNEDY, R. I., N. C. RAWLINGS та S. J. COOK. "EFFECTS OF DIHYDROTESTOSTERONE AND 5α-ANDROSTANE-3α, 17β-DIOL ON SERUM CONCENTRATIONS OF LH AND FSH IN THE PREPUBERTAL BULL". Canadian Journal of Animal Science 65, № 1 (1985): 95–99. http://dx.doi.org/10.4141/cjas85-010.

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Administration of silastic implants releasing dihydrotestosterone or 5α-androstane-3α, 17β-diol to 4-, 14- and 20-wk-old bull calves depressed serum concentrations of LH and FSH, both prior to and following castration. The results suggest that 5α-reduced androgens may be involved in the establishment of negative feedback control of gonadotropins, prior to significant testicular testosterone production. Key words: Bull calves, puberty, androgens, gonadotropins

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Winter, J. S. D., L. Ellsworth, G. Fuller, W. C. Hobson, F. I. Reyes, and C. Faiman. "The role of gonadal steroids in feedback regulation of gonadotropin secretion at different stages of primate development." Acta Endocrinologica 114, no. 2 (1987): 257–68. http://dx.doi.org/10.1530/acta.0.1140257.

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Abstract. The serum gonadotropin response to castration was assessed in 8 foetal, 2 neonatal, 30 juvenile, and 2 adult rhesus monkeys (M. mulatta). In the 30 castrated juvenile monkeys and 8 sham-operated controls, concentrations of oestrone, oestradiol, androstenedione, dihydrotestosterone, testosterone and 17OH-progesterone were measured in 10 ml serum pools before, one month after, and one year after the surgical procedure. Castration during foetal life (83–137 days gestation) was followed within 48–72 h by a significant rise in serum FSH levels in males, but had no effect on the already hi

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Harrison, G. S., M. E. Wierman, T. M. Nett, and L. M. Glode. "Gonadotropin-releasing hormone and its receptor in normal and malignant cells." Endocrine-Related Cancer 11, no. 4 (2004): 725–48. http://dx.doi.org/10.1677/erc.1.00777.

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Gonadotropin-releasing hormone (GnRH) is the hypothalamic factor that mediates reproductive competence. Intermittent GnRH secretion from the hypothalamus acts upon its receptor in the anterior pituitary to regulate the production and release of the gonadotropins, LH and FSH. LH and FSH then stimulate sex steroid hormone synthesis and gametogenesis in the gonads to ensure reproductive competence. The pituitary requires pulsatile stimulation by GnRH to synthesize and release the gonadotropins LH and FSH. Clinically, native GnRH is used in a pump delivery system to create an episodic delivery pat

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Filippa, Verónica, Daiana Godoy, Edith Perez, and Fabian Mohamed. "Effects of castration on androgen receptors and gonadotropins in the pituitary of adult male viscachas." Reproduction, Fertility and Development 26, no. 7 (2014): 991. http://dx.doi.org/10.1071/rd13126.

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The aims of the present study were to determine whether castration results in quantitative immunohistochemical changes in androgen receptors (AR), LH-immunoreactive (IR) cells and FSH-IR cells, and to analyse the colocalisation of AR and gonadotropins in the pituitary pars distalis (PD) of viscachas. Pituitaries were processed for light and electron microscopy. AR-IR, LH-IR and FSH-IR cells were detected by immunohistochemistry. In morphometric studies, the percentage of AR-IR, LH-IR, FSH-IR, LH-IR/AR-IR and FSH-IR/AR-IR cells was determined. In intact viscachas, AR were distributed throughout

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Emanuele, N. V., J. Jurgens, N. La Paglia, D. W. Williams, and M. R. Kelley. "The effect of castration on steady state levels of luteinizing hormone-releasing hormone (LHRH) mRNA and proLHRH processing: time course study utilizing semi-quantitative reverse transcription/polymerase chain reaction." Journal of Endocrinology 148, no. 3 (1996): 509–15. http://dx.doi.org/10.1677/joe.0.1480509.

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Abstract Many studies have consistently shown that castration induces a prompt increase in serum levels and pituitary content of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well as a concomitant rise in steady state levels of the messenger RNAs directing their synthesis. The reports of effects of castration on the overall physiology of hypothalamic luteinizing hormone-releasing hormone (LHRH) — steady state levels of LHRH mRNA, post-translational processing and secretion — have, however, not been consistent. The goal of the studies reported here was t

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TANG, KECHUN, ANDRZEJ BARTKE, CATHERINE S. GARDINER, THOMAS E. WAGNER, and JEUNG S. YUN‡. "Testosterone Feedback on Gonadotropin Secretion and Gene Expression in Transgenic Mice Expressing Human Growth Hormone Gene." Journal of Andrology 15, no. 1 (1994): 9–14. http://dx.doi.org/10.1002/j.1939-4640.1994.tb01673.x.

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ABSTRACT: To determine the effects of testosterone on the regulation of gonadotropins in metallothionein‐1/human growth hormone (MT/hGH) transgenic mice, basal and gonadotropin‐releasing hormone (GnRH)‐stimulated luteinizing hormone (LH) and follicle‐stimulating hormone (FSH) release from incubated pituitaries, as well as pituitary content of LH, FSH, and mRNA for their respective β subunits, were measured in normal and transgenic males that were injected with testosterone propionate (5 μg/g body weight; 24 hours before autopsy), injected with oil vehicle, castrated for 10 days, or sham operat

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Lindzey, Jonathan, William C. Wetsel, John F. Couse, Tammy Stoker, Ralph Cooper та Kenneth S. Korach. "Effects of Castration and Chronic Steroid Treatments on Hypothalamic Gonadotropin-Releasing Hormone Content and Pituitary Gonadotropins in Male Wild-Type and Estrogen Receptor-α Knockout Mice". Endocrinology 139, № 10 (1998): 4092–101. http://dx.doi.org/10.1210/endo.139.10.6253.

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Abstract Testicular androgens are integral components of the hormonal feedback loops that regulate circulating levels of LH and FSH. The sites of feedback include hypothalamic areas regulating GnRH neurons and pituitary gonadotropes. To better define the roles of androgen receptor (AR), estrogen receptor-α (ERα), and estrogen receptor-β (ERβ) in mediating feedback effects of sex steroids on reproductive neuroendocrine function, we have determined the effects of castration and steroid replacement therapy on hypothalamic GnRH content, pituitary LHβ and FSHβ messenger RNA (mRNA) levels, and serum

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Dissertations / Theses on the topic "Gonadotropins and castration"

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Kinch, R. F. T. "Effects of age, photoperiod, and castration on the responsiveness of the pituitary gland of the vole, Microtus agrestis, to stimulation by gonadotrophin-releasing hormone (GnRH)." Thesis, Oxford Brookes University, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374975.

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Machado, Diego Soares. "Uso da imunocastração como alternativa à castração cirúrgica na produção de novilhos para abate." Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/10871.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The objective of this study was to evaluate the use of immunological castration as an alternative to surgical castration in the production of beef cattle. In the research were used 48 Aberdeen Angus male bovines, monitored from initial age of six months and initial average weight of 160 kg at weaning. The animals were randomly distributed in the following treatments: surgically castrated at birth; surgically castrated at weaning; immunocastrated Bopriva® with three doses of vaccine, and immunocastrated Bopriva® with four doses of v

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Book chapters on the topic "Gonadotropins and castration"

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Polat, Hakan, and Yavuz Onur Danacioglu. "Abiraterone Acetate Treatment in Metastatic Prostate Cancer." In Current Management of Metastatic Prostate Cancer. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359142.8.

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Prostate cancer is the frequently presented malignancy in men, and it is expected that nearly 300,000 people will be diagnosed with it in the United States in 2024. Generally, the five-year survival rate is quite positive at 97.5%, but this rate drops to around 30% in cases with advenced disease. Tumors arise from changes in the genetic material of the epithelial cells in the prostate gland and typically appear as adenocarcinomas. Adenocarcinoma of the prostate is found within the gland in a multifocal and heterogeneous manner. Metastases of prostate cancer are hormonally sensitive, the primar

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Krueger, Richard B. "Orchiectomy." In Sex Offenders, edited by Fabian M. Saleh, John M. Bradford, and Daniel J. Brodsky. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190884369.003.0015.

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This chapter presents the historical data supporting bilateral orchiectomy as a possible treatment modality for individuals who have committed sexual crimes or who have paraphilic disorders. Although the idea of orchiectomy, or surgical castration, evokes strongly negative emotional responses in many individuals, several reviews of biological treatments for sex offenders examining recidivism data from European studies have concluded that castration had very significant positive effects on recidivism. Castration for control, domination, punishment, mutilation, social advancement, and political

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