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Journal articles on the topic 'Gonads'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Scolfaro, Márcia Ribeiro, Izilda Aparecida Cardinalli, Eliana Gabas Stuchi-Perez, et al. "Morphometry and Histology of Gonads From 13 Children With Dysgenetic Male Pseudohermaphroditism." Archives of Pathology & Laboratory Medicine 125, no. 5 (2001): 652–56. http://dx.doi.org/10.5858/2001-125-0652-mahogf.

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Abstract Background.—Dysgenetic male pseudohermaphroditism (DMP) is a sexual differentiation disorder characterized by bilateral dysgenetic testes, persistent müllerian structures, and cryptorchidism in individuals with a 46,XY karyotype. However, the histologic criteria for the diagnosis of DMP are poorly established. Objective.—To determine gonadal histology in children with DMP. Patients and Methods.—Between 1996 and 1998, 13 patients with DMP were evaluated on our service. The clinical diagnosis of DMP was based on a 46,XY karyotype, sex ambiguity, high levels of follicle-stimulating hormo

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2

Lin, Xiao, Zidi Jin, Shuo Li, et al. "Preliminary Study on Expression and Function of the Chicken W Chromosome Gene MIER3 in Embryonic Gonads." International Journal of Molecular Sciences 24, no. 10 (2023): 8891. http://dx.doi.org/10.3390/ijms24108891.

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The sex chromosomes of birds are designated Z and W. The male is homogamous (ZZ), and the female is heterogamous (ZW). The chicken W chromosome is a degenerate version of the Z chromosome and harbors only 28 protein-coding genes. We studied the expression pattern of the W chromosome gene MIER3 (showing differential expression during gonadogenesis) in chicken embryonic gonads and its potential role in gonadal development. The W copy of MIER3 (MIER3–W) shows a gonad-biased expression in chicken embryonic tissues which was different from its Z copy. The overall expression of MIER3–W and MIER3–Z m

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3

Suminto, Suminto. "Different Percentages of Gonad Maturity on The Fertility and Haching Rate in Artificial Breeding of Abalone (Haliotis asinina)." Saintek Perikanan : Indonesian Journal of Fisheries Science and Technology 6, no. 1 (2012): 79–87. http://dx.doi.org/10.14710/ijfst.6.1.79-87.

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Abalone is one of the marine mollusk that has high economic value. Mass abalone cultivation requires the mature gonads broodstock to produce seeds, but the maturity of the gonads of male and female often can not be simultaneously. Artificial insemination using a solution of ammonia is one solution to produce abalone seed in the hatchery. Ammonia solution can increase motility, fertilization rate of eggs and abalone seed production, so the provision of seeds for cultivation of abalone is independent from nature. The research of artificial insemination was carried out at various levels of gonada

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4

Bahtiar, Muhammad Fajar Purnama, Rahmadhani, and Muhammad Nur Findra. "The Reproduction of Meretrix meretrix Clams in The Kambu River Estuary, Southeast Sulawesi." Journal of Tropical Fisheries Management 6, no. 1 (2023): 54–60. http://dx.doi.org/10.29244/jppt.v6i1.44443.

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Meretrix meretrix is a degraded resource in Kendari Bay waters, but its reproductive pattern is not fully known.. This study aims to determine the level of gonad maturity, gonadal maturity index, fecundity and the size of the first gonad maturity of M. meretrix at the Kambu River estuary, Kendari Bay, Southeast Sulawesi. This research was carried out at the Kambu River estuary for 6 months from August 2021-January 2022. These clams were taken randomly representing all size classes as many as 300 birds during the study. M. meretrix were observed for gonad color and gonad development microscopic

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5

Verkauskas, Gilvydas, Diana Mačianskytė, Dainius Jančiauskas, Romualdas Preikša, Rasa Verkauskienė, and Francis Jaubert. "Diagnosis and management of 46,XY mixed gonadal dysgenesis and disorder of sexual differentiation." Medicina 45, no. 5 (2009): 357. http://dx.doi.org/10.3390/medicina45050045.

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Objective. We present our experience in diagnosing, gender assignment, and surgical management of sexual ambiguity in 46,XY mixed gonadal dysgenesis. Material and methods. A retrospective study of five cases treated from 2003 to 2006 was performed. Clinical picture, operative findings, testosterone levels, and immunohistochemistry of gonads for the expression of FOXL2, SOX9, AMH, AMHr, C-kit, and PLAP were analyzed. Results. All patients had ambiguous genitalia, urogenital sinus, uterus, testicle on one side, and a streak gonad on the other. Four patients were reared as male and one as female.

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6

Fredricsson, Bengt, Kjell Carlström, Berndt Kjessler, et al. "Incomplete androgen insensitivity: asymmetry in morphology and steroid profile and metabolism of the gonads. An analysis of a case." Acta Endocrinologica 110, no. 4 (1985): 564–71. http://dx.doi.org/10.1530/acta.0.1100564.

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Abstract. A patient with clinical manifestations of the incomplete androgen insensitivity syndrome was studied with respect to peripheral blood levels of steroids and steroid sulphates before, during and after gonadectomy. Steroid and steroid sulphate concentrations were also analyzed in spermatic venous blood and gonadal tissue collected during surgery. The metabolic capacity of gonadal tissue was also studied in vitro using progesterone, dehydroepiandrosterone sulphate and oestrone sulphate as substrates. Profound differences between the two gonads were noted with respect to both steroid con

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7

Chen, Yadong, Yongtao Xia, Changwei Shao, et al. "Discovery and identification of candidate sex-related genes based on transcriptome sequencing of Russian sturgeon (Acipenser gueldenstaedtii) gonads." Physiological Genomics 48, no. 7 (2016): 464–76. http://dx.doi.org/10.1152/physiolgenomics.00113.2015.

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As the Russian sturgeon ( Acipenser gueldenstaedtii) is an important food and is the main source of caviar, it is necessary to discover the genes associated with its sex differentiation. However, the complicated life and maturity cycles of the Russian sturgeon restrict the accurate identification of sex in early development. To generate a first look at specific sex-related genes, we sequenced the transcriptome of gonads in different development stages (1, 2, and 5 yr old stages) with next-generation RNA sequencing. We generated >60 million raw reads, and the filtered reads were assembled in

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8

Mogontha, Lolouren, Nego E. Bataragoa, and Ari B. Rondonuwu. "Biology Reproduction Of Banggai Cardinal Fish Pterapogon kauderni Koumans, 1933 In Lembeh Strait." JURNAL PERIKANAN DAN KELAUTAN TROPIS 11, no. 1 (2020): 33. http://dx.doi.org/10.35800/jpkt.11.1.2020.28734.

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This research was conducted to determine the reproductive aspects of Banggai Cardinal Fish (Pterapogon kauderni) in the Lembeh Strait. Fish samples were obtained by “Small Chang Net” in the Lembeh Strait. The total sample was 150 individuals. Sex Ratio of Pterapogon kauderni in Serena Besar Island 1: 1, in LIPI 1: 1 water, and in Papusungan waters 1: 1. IKG Pterapogon kauderni in Serena besar location in females obtained 0.26 ± 0.21 and in males 0, 26 ± 0.13. Location of Papusungan, females obtained 1.25 ± 1.00 and in males 0.37 ± 0.16. Then finally, at the LIPI location, females obtained 0.64

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Paul-Prasanth, Bindhu, Yasushi Shibata, Ryo Horiguchi, and Yoshitaka Nagahama. "Exposure to Diethylstilbestrol During Embryonic and Larval Stages of Medaka Fish (Oryzias latipes) Leads to Sex Reversal in Genetic Males and Reduced Gonad Weight in Genetic Females." Endocrinology 152, no. 2 (2011): 707–17. http://dx.doi.org/10.1210/en.2010-0812.

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Abstract Molecular and cellular mechanisms involved in artificially induced ovarian differentiation were analyzed by exposing embryos of medaka (Oryzias latipes) to a potent nonsteroidal estrogen, diethylstilbestrol (DES). Embryos were exposed for short-exposure (SE) [from 0 to 8 d postfertilization (dpf)] and long-exposure (LE) periods (from 0 to 18/28 dpf) to 1 ng/ml of DES, and status of sexual differentiation in somatic and germ cells of these gonads was analyzed at 8, 18, and 28 dpf by histology, cell proliferation assays, TUNEL assay, and in situ hybridization using sex-specific somatic

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10

Wagiyo, Karsono, Ali Suman, and Mufti Petala Patria. "SEBARAN DAN HUBUNGAN PARAMETER REPRODUKSI IKAN TUNA MADIDIHANG (Thunnus albacares) DENGAN SUHU DAN KLOROFIL-a DI LAUT BANDA." BAWAL Widya Riset Perikanan Tangkap 7, no. 3 (2015): 183. http://dx.doi.org/10.15578/bawal.7.3.2015.183-191.

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Laut Banda diketahui mempunyai kondisi lingkungan yangmendukung sebagai daerah pemijahan ikan tuna madidihang (Thunnus albacares). Sebaran parameter reproduksi dan hubungannya dengan lingkungan perlu diketahui sebagai dasar pengelolaan sumberdaya yang lestari. Penelitian dilakukan tahun 2011-2012 dengan basis pendataan di Bandaneira. Pengamatan parameter reproduksi dilakukan terhadap ikan sampel melalui observasi dan enumerasi. Suhu dan klorofil-a diperoleh = dari analisis citra satelit. Penelitian mendapatkan persentase gonad matang (100 %) dan indeks kematangan gonad tertinggi (3,75) serta n

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Pieau, C., and M. Dorizzi. "Oestrogens and temperature-dependent sex determination in reptiles: all is in the gonads." Journal of Endocrinology 181, no. 3 (2004): 367–77. http://dx.doi.org/10.1677/joe.0.1810367.

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In many species of oviparous reptiles, the first steps of gonadal sex differentiation depend on the incubation temperature of the eggs. Feminization of gonads by exogenous oestrogens at a male-producing temperature and masculinization of gonads by antioestrogens and aromatase inhibitors at a female-producing temperature have irrefutably demonstrated the involvement of oestrogens in ovarian differentiation. Nevertheless, several studies performed on the entire gonad/adrenal/mesonephros complex failed to find differences between male- and female-producing temperatures in oestrogen content, aroma

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12

Luo, Huaixi, Hao Zhou, Shengyao Jiang, et al. "Gene Expression Profiling Reveals Potential Players of Sex Determination and Asymmetrical Development in Chicken Embryo Gonads." International Journal of Molecular Sciences 24, no. 19 (2023): 14597. http://dx.doi.org/10.3390/ijms241914597.

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Despite the notable progress made in recent years, the understanding of the genetic control of gonadal sex differentiation and asymmetrical ovariogenesis in chicken during embryonic development remains incomplete. This study aimed to identify potential key genes and speculate about the mechanisms associated with ovary and testis development via an analysis of the results of PacBio and Illumina transcriptome sequencing of embryonic chicken gonads at the initiation of sexual differentiation (E4.5, E5.5, and E6.5). PacBio sequencing detected 328 and 233 significantly up-regulated transcript isofo

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13

Mustać, Bosiljka, and Gorenka Sinovčić. "Oogenesis and spermatogenesis in round sardinella (Sardinella aurita Valenciennes, 1847) from the eastern part of the Adriatic Sea." Periodicum Biologorum 123, no. 3-4 (2022): 89–94. http://dx.doi.org/10.18054/pb.v123i3-4.6883.

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Background and purpose: Small pelagic fish species round sardinella (Sardinella aurita) has expanded its habitat during the last few decades towards colder parts of the Mediterranean Sea. In the Adriatic Sea, this investigation is the first attempt to study its gonad development histologically.Materials and methods: S. aurita specimens were sampled monthly from commercial landings of purse seine catches from the eastern part of the Adriatic Sea from November 2007 to January 2009. After biometric parameters were determined, gonads were removed from the fish and weighed. Sex and gonad developmen

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14

Sembiring, Sari Budi Moria, John Harianto Hutapea, Ahmad Muzaki, Ida Komang Wardana, Ni Wayan Widya Astuti, and Retno Andamari. "REPRODUCTIVE ASPECTS OF CULTURED HUMPBACK GROUPER (Cromileptes altivelis) FOR SUPPORTING SEED PRODUCTION." Indonesian Aquaculture Journal 9, no. 1 (2014): 1. http://dx.doi.org/10.15578/iaj.9.1.2014.1-8.

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Humpback grouper (Cromileptes altivelis) has been successfully spawned in 2000 by IMRAD (Institute of Mariculture Research and Development) and there are already the third generation (F3) currently. The reproductive aspects need to be studied to support the success of seed production. Humpback grouper reared in floating cage (F1 and F3) had matured (gonad stage 4) while F2 fish reared in concrete tanks has spawned. Gonadal maturity stage of 38 fishes from first generation (F1) and 35 fishes from the third generation were observed in June 2013 and compared to gonadal maturity stage of 18 fishes

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15

McGuire, Nicolette L., Kristina Kangas, and George E. Bentley. "Effects of Melatonin on Peripheral Reproductive Function: Regulation of Testicular GnIH and Testosterone." Endocrinology 152, no. 9 (2011): 3461–70. http://dx.doi.org/10.1210/en.2011-1053.

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Study of seasonal reproduction has focused on the brain. Here, we show that the inhibition of sex steroid secretion can be seasonally mediated at the level of the gonad. We investigate the direct effects of melatonin on sex steroid secretion and gonadal neuropeptide expression in European starlings (Sturnus vulgaris). PCR reveals starling gonads express mRNA for gonadotropin inhibitory hormone (GnIH) and its receptor (GnIHR) and melatonin receptors 1B (Mel 1B) and 1C (Mel 1C). We demonstrate that the gonadal GnIH system is regulated seasonally, possibly via a mechanism involving melatonin. GnI

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Kobayashi, Yasuhisa, Masaru Nakamura, Tomoki Sunobe, et al. "Sex Change in the Gobiid Fish Is Mediated through Rapid Switching of Gonadotropin Receptors from Ovarian to Testicular Portion or Vice Versa." Endocrinology 150, no. 3 (2008): 1503–11. http://dx.doi.org/10.1210/en.2008-0569.

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Sex-changing fish Trimma okinawae can change its sex back and forth from male to female and then to male serially, depending on the social status in the harem. T. okinawae is well equipped to respond to its social status by possessing both ovarian and testicular tissues even though only one gonad remains active at one time. Here we investigated the involvement of gonadotropins in sex change by determining the changes in gonadotropin receptor (GtHR) gene expression during the onset of sex change from female to male and male to female. The expression of the GtHR was found to be confined to the a

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17

Bergeron, Mélanie Beaulieu, Nicole Lemieux, and Pierre Brochu. "Undifferentiated Gonadal Tissue, Y Chromosome Instability, and Tumors in XY Gonadal Dysgenesis." Pediatric and Developmental Pathology 14, no. 6 (2011): 445–59. http://dx.doi.org/10.2350/11-01-0960-oa.1.

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Patients with XY gonadal dysgenesis are at increased risk of developing gonadal tumors. The etiology of several cases of XY gonadal dysgenesis remains unknown, but X/XY gonadal mosaicism has been hypothesized to play a role. At the histologic level, the presence of persistent primitive sex cords containing immature germ cells in dysgenetic gonads (an entity called undifferentiated gonadal tissue, or UGT) was recently described, and these immature germ cells are thought to be at risk of neoplastic transformation. To further investigate both these aspects, we retrospectively studied the gonads f

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18

Tevosian, Sergei G., Kenneth H. Albrecht, John D. Crispino, Yuko Fujiwara, Eva M. Eicher, and Stuart H. Orkin. "Gonadal differentiation, sex determination and normalSryexpression in mice require direct interaction between transcription partners GATA4 and FOG2." Development 129, no. 19 (2002): 4627–34. http://dx.doi.org/10.1242/dev.129.19.4627.

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In mammals, Sry expression in the bipotential, undifferentiated gonad directs the support cell precursors to differentiate as Sertoli cells, thus initiating the testis differentiation pathway. In the absence of Sry, or if Sry is expressed at insufficient levels, the support cell precursors differentiate as granulosa cells, thus initiating the ovarian pathway. The molecular mechanisms upstream and downstream of Sry are not well understood. We demonstrate that the transcription factor GATA4 and its co-factor FOG2 are required for gonadal differentiation. Mouse fetuses homozygous for a null allel

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Xu, Dongdong, Tasuku Yoshino, Marcelo de Bello Cioffi, et al. "Production of donor-derived eggs after ovarian germ cell transplantation into the gonads of adult, germ cell-less, triploid hybrid fish†." Biology of Reproduction 103, no. 6 (2020): 1289–99. http://dx.doi.org/10.1093/biolre/ioaa168.

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Abstract In animals, spermatogonial transplantation in sterile adult males is widely developed; however, despite its utility, ovarian germ cell transplantation is not well developed. We previously showed that the interspecific hybrid offspring of sciaenid was a suitable model for germ cell transplantation studies as they have germ cell-less gonads. However, all these gonads have testis-like characteristics. Here, we tested whether triploidization in hybrid embryos could result in germ cell-less ovary development. Gonadal structure dimorphism and sex-specific gene expression patterns were exami

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Cossi, Paula F., Claudia C. Boy, and Analía F. Pérez. "Pattern of energy allocation during the gametogenesis of the asteroid Cosmasterias lurida (Forcipulatida: Stichasteridae) from the Beagle Channel, Ushuaia, Argentina." Revista de Biología Tropical 65, no. 1-1 (2017): 197. http://dx.doi.org/10.15517/rbt.v65i1-1.31688.

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Energy allocation patterns during the reproductive cycle of echinoderms may be determined by the different energy requirements of the organisms. In this study, we describe the energy reserves variation in the gonads, pyloric caeca and stomach among the gametogenic stages of a population of Cosmasterias lurida from the Beagle Channel, Argentina. Adult individuals of C. lurida were collected from the subtidal zone of Ushuaia Bay during four seasonal sampling periods (August 2010 to June 2011). Indices, energy density (kJ/g ash-free dry mass) and energy content (kJ) of gonads, pyloric caeca and s

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Frojdman, K., J. Paranko, T. Kuopio, and L. J. Pelliniemi. "Structural proteins in sexual differentiation of embryonic gonads." International Journal of Developmental Biology 33, no. 1 (1989): 99–103. https://doi.org/10.1387/ijdb.2485707.

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Sexual differentiation of embryonic gonads was studied by immunocytochemical analysis of cytoskeleton, basement membrane and extracellular matrix. The epithelial cells of the prospective gonadal region in both sexes contained vimentin and desmin intermediate filament proteins but not cytokeratin. Basement membrane components laminin, collagen types IV and V, heparan sulfate proteoglycan, and fibronectin were seen in an unorganized form in the extracellular space. The development of the gonads started by proliferation of the pregonadal epithelial cells, which formed separate clusters and loose

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Despalatović, Marija, Ivana Grubelić, Ante šimunović, Boris Antolić, and Ante Žuljević. "Reproductive biology of the holothurian Holothuria tubulosa (Echinodermata) in the Adriatic Sea." Journal of the Marine Biological Association of the United Kingdom 84, no. 2 (2004): 409–14. http://dx.doi.org/10.1017/s0025315404009361h.

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The reproductive cycle of a local population the aspidochirote Holothuria tubulosa in Kaštela Bay (Adriatic Sea) was analysed from July 1994 to August 1995 by histological examination and observations of macroscopic features of the gonads. Five gonadal stages were described: recovery stage, growing stage, mature stage, spawning stage, and post-spawning stage. The distinguishing features used to describe gonad stages in both sexes included the main features of reproductive cells and gonad wall. The reproductive cycle showed a clear annual pattern and was synchronous in both sexes. Spawning occu

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Tolon, Mustafa Tolga, and Serhat Engin. "Gonadal development of the holothurian Holothuria polii (Delle Chiaje, 1823) in spawning period at the Aegean Sea (Mediterranean Sea)." Ege Journal of Fisheries and Aquatic Sciences 36, no. 4 (2019): 379–85. http://dx.doi.org/10.12714/egejfas.36.4.09.

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The Mediterranean sea cucumbers including Holothuria polii has become commercially important in international trade due to the high demand of consumers from Far East countries. Sea cucumbers fisheries is a valuable income for the regional fishermen but natural stocks endangered by overfishing in recent years. Fisheries regulations and aquaculture studies are important precautions for preserving natural stocks. All these efforts are based on reproduction biology of this species which slightly differed among regions. In this study, the reproduction biology including morphological characteristics

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Wen, Aiyun, Feng You, Peng Sun, et al. "Sexually dimorphic gene expression patterns during gonadal differentiation in olive flounder, Paralichthys olivaceus." Animal Biology 65, no. 3-4 (2015): 193–207. http://dx.doi.org/10.1163/15707563-00002470.

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The present study aims to elucidate the different expression patterns and possible roles of Doublesex and Mab-3-related transcription factor 1 (dmrt1), dmrt4, SRY-related transcription factor 9 (sox9) and cytochrome P450 aromatase 19a (cyp19a) during gonadal differentiation in olive flounder, Paralichthys olivaceus. We first analyzed the gene expression patterns in tissues using RT-PCR, which indicated dmrt1, sox9 and cyp19a were sex-related genes with sexual dimorphic expression. The quantitative expression changes of these three genes together with dmrt4 during gonadal differentiation were f

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Hasibuan, J. S., J. S. Ulfa, Desrita, V. R. Manurung, and J. Sinaga. "The gonad maturity level of kawakawa (Euthynus affinis) landed at Tanjung Beringin’s auction place Serdang Bedagai Regency of North Sumatra." IOP Conference Series: Earth and Environmental Science 1221, no. 1 (2023): 012024. http://dx.doi.org/10.1088/1755-1315/1221/1/012024.

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Abstract Kawakawa (Euthynnus affinis) is one of the economically valuable species for Mallaca strait fishermen. This study aims to determine the level of gonad maturity, the size of the fish’s first ripe gonad, and the gonad maturity index of Kawakawa (E. affinis) caught at Tanjung Beringin’s Auction Place, Serdang Bedagai Regency, North Sumatra. Three months of sampling were conducted, from July to September 2021. The maturation of gonads was observed morphologically. Kawakawa (E. affinis) GMI was analyzed based on a comparison between gonad weight and body weight. Male and female Kawakawa go

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Çek, Şehriban. "Early gonadal development and sex differentiation in rosy barb (Puntius conchonius)." Animal Biology 56, no. 3 (2006): 335–50. http://dx.doi.org/10.1163/157075606778441895.

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AbstractThe main objective of this study was to describe the early gonadal development and to examine the process of sex differentiation in male and female P. conchonius under laboratory conditions. First evidence of primordial germ cells was observed on the day of hatching. The sex differentiation in leptotene, zygotene, pachytene and diplotene stages was clearly detected. Differentiation started from the mid-mid posterior part of the gonads. Actual sex differentiation occurred between 18-21 days and 36-40 days post-hatching in females and males, respectively. Histological sex differentiation

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Habibah, Aulidya Nurul, Rika P.C. Pertiwi, and Titi Chasanah. "Gonadal Differentiation of Nilem Fish (Osteochilus vittatus) Utilizing Temperature Treatment." BIOEDUSCIENCE 4, no. 2 (2020): 143–47. http://dx.doi.org/10.22236/j.bes/425704.

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Background: Gonad differentiation in some teleostei is a critical phase of gonad development. Gonad differentiation in some fish such as the tilapia group is influenced by environmental factors, namely temperature. The aim of this study was to determine the differentiation process of Nilem fish gonads (Osteochilus vittatus) under the influence of temperature. Methods: One day after fertilization (days postfertilization/dpf) fish were exposed to different medium temperature ranges, namely: 28-29 oC, 30-31 oC, 32-33 oC, and room temperature as a control for 35 days. The percentage of fish surviv

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Raygorodskaya, Nadezda Y., Nina V. Bolotova, Danil A. Jarkov, Tatyana V. Palatova, and Natalya S. Dorovskaya. "Ovotesticular disorder of sexual development in a patient with 46,XY karyotype." Problems of Endocrinology 63, no. 3 (2017): 201–3. http://dx.doi.org/10.14341/probl2017633201-203.

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A 46,XY ovotesticular disorder of sexual development is a rare variant of pathological gonadal differentiation. A 15-month-old patient had ambiguous external genitalia, no palpable gonads, and the 46,XY karyotype. The uterus was detected by imaging of the lesser pelvis. Gonads resided on the fallopian tubes and macroscopically resembled ovotestes: each gonad consisted of two compartments separated by a connective tissue interlayer. Histological examination showed that one gonadal portion consisted for ovarian tissue, was differentiated into the cortical and medullary matter, and contained prim

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Torres-Cano, Alejo, Rosa Portella-Fortuny, Claudia Müller-Sánchez, et al. "Deletion of Wt1 during early gonadogenesis leads to differences of sex development in male and female adult mice." PLOS Genetics 18, no. 6 (2022): e1010240. http://dx.doi.org/10.1371/journal.pgen.1010240.

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Assessing the role of the WT1 transcription factor (WT1) during early gonad differentiation and its impact on adult sex development has been difficult due to the complete gonadal agenesis and embryonic lethality exhibited by Wt1KO mouse models. Here, we generated Wt1LoxP/GFP;Wt1Cre mice, the first Wt1KO mouse model that reaches adulthood with a dramatically reduced Wt1 expression during early gonadogenesis. Wt1LoxP/GFP;Wt1Cre mice lacked mature gonads and displayed genital tracts containing both male and female genital structures and ambiguous genitalia. We found that WT1 is necessary for the

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Kostaman, Tatan, and S. Sopiyana. "Development and Conservation of Gonadal Primordial Germ Cells for Preservation of Local Chicken in Indonesia." Indonesian Bulletin of Animal and Veterinary Sciences 26, no. 3 (2017): 125. http://dx.doi.org/10.14334/wartazoa.v26i3.1394.

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One of the <em>ex situ</em> conservation techniques for poultry that recently developed was to collect primordial germ cell (PGC) or gonadal primordial germ cell (gPGC) that isolated from embryo development. Primordial germ cells (PGC) are embryonic cells that migrate to the gonads and form the precursors of gametes. The unique nature and accessibility of PGC during the early development provides an opportunity to manipulate the poultry germplasm, for example by forming germline chimeras. There are some stages that must be done through isolation and collection of PGC from its resou

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Durmuş, Gül, Ozlem Boybeyi-Turer, Hatice Nursun Özcan, Onur Gözmen, Hüseyin Demirbilek, and Tutku Soyer. "Continuous Hepatogonodal and Splenogonogal Fusion: A Rare Cause of Bilateral Intra-Abdominal Testis in an 18-Month-Old Boy." European Journal of Pediatric Surgery Reports 10, no. 01 (2022): e80-e83. http://dx.doi.org/10.1055/s-0042-1747671.

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AbstractThe fusion of gonadal structures with internal organs is very rare. The close proximity between the left gonad and spleen during embryogenesis may result in splenogonadal fusion (SGF). Moreover, the trapping of hepatocyte-destined mesenchyme cells in gonads is defined as hepatogonadal fusion (HGF). The fusion of gonads with intra-abdominal organs may be continuous and may impair testicular descent during the prenatal period. We herein report an 18-month-old boy presented with bilateral nonpalpable testis due to concomitant continuous HGF and SGF. To our knowledge, this is the first cas

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M. Aprillia, Reskyta, Agustinus Tupamahu, Friesland Tuapetel, and Haruna Haruna. "Reproductive Biology of Pterocaesio tile (Cuvier, 1830) in Supporting Responsible Fisheries Encircling Gillnet." Agrikan Jurnal Agribisnis Perikanan 16, no. 1 (2023): 28–34. http://dx.doi.org/10.52046/agrikan.v16i1.1432.

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Pterocaesio tile are generally caught by encircling gill nets using the schooling behavior of these species. The purpose of this study was analyze the biological reproduction of P. tile which induced sex ratio, gonadal maturity level, gonadal maturity index and size at first maturity. Data collection was carried out from October to December 2022. The data collection method was conducted using experimental fishing methods by operating unit gill net with mesh size of 1,75 and 2,0 inch. Fish samples of each actual fishing were measured total length and weight, dissected to determine sex, measured

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Fujaya, Yushinta, Andi Aliah Hidayani, Marlina Achmad, Aisyah Nurfadilah Abdullah, Muhammad Aliafid, and Dwi Kesuma Sari. "Bitter Melon (Momordica charantia L) Fruit Extract Affects The Gonad Development and Ovulation of Female Tilapia (Oreochromis niloticus); Study of Gonadal Morphology and Histopathology." Aquacultura Indonesiana 24, no. 2 (2024): 46–52. http://dx.doi.org/10.21534/ai.v24i2.2.

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One of the problems in the cultivation of tilapia (Oreochromis niloticus) is the ability to reproduce early and quickly mature gonads so that the fish kept are difficult to reach the size of market demand. This study aims to determine the effect of various doses of bitter melon fruit extract on the development of female gonads and to study the histopathological changes in the structure of the gonad. This research was carried out in July-September 2021. There were 600 juveniles of tilapia used in this study. Tilapia rearing was carried out in 12 containers (each 200 L volume of water) for 60 da

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Lin, Feng, Konrad Dabrowski, and Lucy P. M. Timmermans. "Early gonadal development and sexual differentiation in muskellunge (Esox masquinongy)." Canadian Journal of Zoology 75, no. 8 (1997): 1262–69. http://dx.doi.org/10.1139/z97-149.

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Primordial germ cells (PGCs) were first identified in muskellunge (Esox masquinongy) of 14 mm total length (TL) 3 weeks post fertilization. At 32 mm TL, gonad strings were complete and formed a typical gonad shape in cross section. Blood vessels were first found in the gonads with Crossmon staining at 46 mm TL. Some of the PGCs underwent mitotic division at this stage. The ovarian sac started to develop in a fish of 82 mm TL, while the germ cells were still considered to be undifferentiated. In a fish of 138 mm TL, female gonads could be clearly identified from the ovarian sac and groups of oo

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Mutlen, Melvin, Paul Zango, Tchouppe Franck Juve Fotio, Sockeng Yannick Kenne, and Eyango Minette Tomedi. "Survival, Growth Performance and Changes in Gonads of Oreochromis niloticus (Linnaeus, 1758) Fed with Mango (Mangifera indica) Leaves Meal Diet." Journal of Aquaculture Research & Development 15, no. 12 (2024): 9. https://doi.org/10.35248/2155-9546.24.15.845.

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The aim of the present study was to explore the possible use of Mangifera indica leaf powder as a reproductive inhibitor in Oreochromis niloticus. To this end, 450 juveniles with an average weight of 11.11 g ± 0.61 g were randomly distributed in 15 happas measuring 0.7 m × 0.7 m × 1 m placed in a tarpaulin tank with a usable volume of 12 m3 , at a density of 30 juveniles per happa and subjected to natural temperature and light conditions and fed 4 experimental diets, formulated from a control diet to contain Mangifera indica leaf powder at doses of 2 g/kg, 4 g/kg, 6 g/kg and

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Porras-Gómez, Tania Janeth, Adriana Martínez-Juárez, and Norma Moreno-Mendoza. "Gonadal morphogenesis and establishment of the germline in the phyllostomid bat Sturnira lilium." Acta Histochemica 119, no. 7 (2017): 671–79. https://doi.org/10.5281/zenodo.14821489.

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(Uploaded by Plazi for the Bat Literature Project) In vertebrates such as the mouse and the human, primordial germ cells (PGCs) arise at the base of the allantois and are carried to the epithelium of the posterior intestine, to later migrate to the primordial gonads. In the case of bats, almost nothing is known about this process. To clarify the dynamics of PGCs during gonadal morphogenesis in the phyllostomid bat Sturnira lilium, the proteins for the Ddx4, Sox9 and Mis genes were detected in the gonads of embryos at different stages of development. We identified 15 stages (St) of embryonic de

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Tilmann, C., and B. Capel. "Mesonephric cell migration induces testis cord formation and Sertoli cell differentiation in the mammalian gonad." Development 126, no. 13 (1999): 2883–90. http://dx.doi.org/10.1242/dev.126.13.2883.

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In mammals a single gene on the Y chromosome, Sry, controls testis formation. One of the earliest effects of Sry expression is the induction of somatic cell migration from the mesonephros into the XY gonad. Here we show that mesonephric cells are required for cord formation and male-specific gene expression in XY gonads in a stage-specific manner. Culturing XX gonads with an XY gonad at their surface, as a ‘sandwich’, resulted in cell migration into the XX tissue. Analysis of sandwich gonads revealed that in the presence of migrating cells, XX gonads organized cord structures and acquired male

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Liang, Weiqian, Lanyuan Liu, Dingxian Chen, et al. "De Novo Assembly, Characterization and Comparative Transcriptome Analysis of the Mature Male and Female Gonads in Acrossocheilus parallens." Animals 15, no. 6 (2025): 806. https://doi.org/10.3390/ani15060806.

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Acrossocheilus parallens has become an important commercial aquaculture species in southern China due to its high nutritional content and ornamental value. However, at present, there is very little research on its gonad development and reproductive regulation, which has restricted the development of its aquaculture industry. In this research, the gonadal transcriptome sequencing data of female and male A. parallens were first analyzed and compared. A total of 67,251 unigenes were successfully assembled and a total of 34,069 unigenes were annotated. After the comparative transcriptome analysis,

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Liu, Qiaolin, Shitao Hu, Xiangbei Tang, et al. "Gonadal Development and Differentiation of Hybrid F1 Line of Ctenopharyngodon idella (♀) × Squaliobarbus curriculus (♂)." International Journal of Molecular Sciences 25, no. 19 (2024): 10566. http://dx.doi.org/10.3390/ijms251910566.

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The hybrid F1 offspring of Ctenopharyngodon idella (♂) and Squaliobarbus curriculus (♀) exhibit heterosis in disease resistance and also show abnormal sex differentiation. To understand the mechanism behind gonadal differentiation in the hybrid F1, we analyzed the transcriptomes of C. idella, S. curriculus, and the hybrid F1; screened for genes related to gonad development in these samples; and measured their expression levels. Our results revealed that compared to either C. idella or S. curriculus, the gene expressions in most sub-pathways of the SNARE interactions in the vesicular transport

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Sarraj, M. A., P. J. McClive, A. Szczepny, H. Daggag, K. L. Loveland, and A. H. Sinclair. "Expression of Wsb2 in the developing and adult mouse testis." Reproduction 133, no. 4 (2007): 753–61. http://dx.doi.org/10.1530/rep.1.01184.

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We present a detailed study of the expression pattern of WD repeat and SOCS box-containing 2 (Wsb2) in mouse embryonic and adult gonads. Wsb2 was previously identified in a differential screen aimed at identifying the genes involved in male- and female-specific gonadal development. Wsb2 expression was analysed during mouse gonadogenesis by real-time PCR, whole-mount and section in situ hybridisation and immunofluorescence. Wsb2 mRNA expression was initially detected in gonads of both sexes from 11.5 days post coitum (dpc) until 12.0 dpc. By 12.5 dpc and thereafter, Wsb2 expression rapidly decr

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Ekawaty, Rani, and Irwan Jatmiko. "Reproductive biology of kawakawa, Euthynnus affinis (Cantor, 1849) in Eastern Indian Ocean." Jurnal Iktiologi Indonesia 18, no. 3 (2019): 199. http://dx.doi.org/10.32491/jii.v18i3.313.

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Kawakawa (Euthynnus affinis) is one of the economically important fish species for fishermen in Denpasar, Bali. The objective of this study was to analyze the reproductive biology of kawakawa such as the gonadal maturity level (GML), gonad maturity index (GMI) and the length proportion of the mature gonads 50% (L50) and 95% (L95) of kawakawa in the Eastern Indian Ocean. Fish samples were collected from the fishermen catch landed at Kedonganan Fishing Port (PPI), Bali from May to September 2016. The total of fish samples collected were 168 individual. Each individual species was measured their

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Katoh-Fukui, Yuko, Kanako Miyabayashi, Tomoko Komatsu, et al. "Cbx2, a Polycomb Group Gene, Is Required for Sry Gene Expression in Mice." Endocrinology 153, no. 2 (2012): 913–24. http://dx.doi.org/10.1210/en.2011-1055.

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Mice lacking the function of the polycomb group protein CBX2 (chromobox homolog 2; also known as M33) show defects in gonadal, adrenal, and splenic development. In particular, XY knockout (KO) mice develop ovaries but not testes, and the gonads are hypoplastic in both sexes. However, how CBX2 regulates development of these tissues remains largely unknown. In the present study, we used microarray, RT-PCR, and immunohistochemical analyses to show that the expression of Sry, Sox9, Lhx9, Ad4BP/SF-1, Dax-1, Gata4, Arx, and Dmrt1, genes encoding transcription factors essential for gonadal developmen

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Morozov, D. A., N. Yu Raygorodskaya, N. V. Bolotova, E. S. Pimenova, G. N. Maslyakova, and E. N. Tsmokalyuk. "The disturbed gonadal differentiation: dysgenesis and ovotesticular disorder of sex formation." Problems of Endocrinology 61, no. 1 (2015): 31–35. http://dx.doi.org/10.14341/probl201561131-35.

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The objective of the present study was differential diagnostics between ovotestis and gonadal dysgenesis, the choice of the gender and the surgical strategy for the treatment of abnormal sexual glands. Diagnostics of the disturbances of gonadal differentiation (DGD) requires morphological verification. The ovotesticular gonad is characterized by the presence of a mature ovarian tissue and a dysgenetic testicular component. The authors describe the surgical separation of the ovotestis with preservation of the segments represented by the mature ovarian tissue. The presence of immature ovarian el

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Shang, Wen-Hui, Jia-Run Han, Jia-Nan Yan, et al. "Quantitative Proteome Reveals Variation in the Condition Factor of Sea Urchin Strongylocentrotus nudus during the Fishing Season Using an iTRAQ-based Approach." Marine Drugs 17, no. 7 (2019): 397. http://dx.doi.org/10.3390/md17070397.

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To investigate the variation in the condition factor of the sea urchin Strongylocentrotus nudus (S. nudus), gonads were collected in May (MAY), June (JUN), and July (JUL), at the beginning (AUG-b) and end of August (AUG-e). Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) detection of the gonads revealed an obvious enhancement of the band at about 37 kDa from July, which was identified as transforming growth factor-beta-induced protein ig-h3 (TGFBI) by nanoLC-ESI-MS/MS. Gonadal proteins were identified by isobaric tagging for relative and absolute quantitation (iTRAQ), and

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Shen, Yunwang, Ziyi Wang, Yanglei Jia, and Xiao Liu. "Integrated Genomic and Transcriptomic Analysis Reveals a Transcription Factor Gene Set Facilitating Gonadal Differentiation in the Pacific Oyster Crassostrea gigas." Genes 16, no. 5 (2025): 513. https://doi.org/10.3390/genes16050513.

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Background/Objectives: The Pacific oyster Crassostrea gigas has emerged as a promising model system for sex determination studies due to its complex reproduction strategy and sex reversal. Transcription factors (TFs) play crucial roles in sex determination and gonadal differentiation. Despite previous research revealing functions of several conserved sex-determining pathway genes, such as Dmrt1, Foxl2, and SoxH, little is known about the other essential TF regulators driving C. gigas gonadal differentiation and development. Methods: In this study, a systematic identification of TFs revealed 11

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Madjid, Rizky, Syafyudin Yusuf, Inayah Yasir, Chair Rani, and Abdul Rasyid Jalil. "PRELIMINARY OBSERVATIONS OF THE DEVELOPMENT OF GONAD PIGMENTATION AS A REPRODUCTIVE PATTERNS OF FAVIIDAE IN SPERMONDE ARCHIPHELAGO, INDONESIA." Jurnal Ilmu Kelautan SPERMONDE 9, no. 1 (2023): 20–26. http://dx.doi.org/10.20956/jiks.v9i1.19956.

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Coral spawning occurs throughout the year in Indonesia due to tropical climate conditions that influence coral development and spawning. As representative data on coral gonad development in the Spermonde Archipelago, observations on the development of the Faviidae gonads were conducted on Barrang Lompo, Kodingareng Keke, Samalona, and Bonetambung Island. Environmental elements are measured in the form of surface water temperature and rainfall. Based on the abundance of this type of gigantic coral at the study site, coral tissue sampling was concentrated on the Faviidae. The pigmentation of the

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Vives, Ailet, Tamara Rubilar, María-Dinorah Herrero-Pérezrul, and Bertha-Patricia Ceballos-Vázquez. "Reproduction of the sea urchin Tripneustes depressus (Camarodonta: Toxopneustidae) in Bahía de La Paz, Baja California Sur, Mexico." Revista de Biología Tropical 69, Suppl.1 (2021): 202–18. http://dx.doi.org/10.15517/rbt.v69isuppl.1.46353.

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Introduction: Sea urchin gonads (roe or uni) are considered a culinary delicacy worldwide. However, only a few species are considered edible and commercialized. The sea urchin Tripneustes depressus has generated the interest of producers in Baja California Sur, Mexico, due to the quality of its gonads. A biological basis for designing a management strategy is key to consider its commercial exploitation. Objective: To determine the reproductive season of T. depressus through description of the gonad stages and reproductive cycle, and to establish its relationship with environmental factors. Met

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Setiyawan, Wahyu, Jusuf Leiwakabessy, and Meigy N. Mailoa. "PROFIL ASAM AMINO GONAD BULU BABI Tripneustes gratilla." INASUA: Jurnal Teknologi Hasil Perikanan 5, no. 1 (2025): 7–15. https://doi.org/10.30598/jinasua.2025.5.1.7.

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Bulu babi Tripneustes gratilla merupakan kelompok hewan bercangkang lunak yang termasuk dalam Filum Echinodermata dan tidak memiliki tulang belakang. Gonad bulu babi memiliki nilai gizi tinggi tapi belum dikelola dan dimanfaatkan secara optimal di Pulau Osi, Kecamatan Seram Barat, Kabupaten Seram Bagian Barat. Tujuan penelitian untuk mengetahui kandungan profil asam amino gonad bulu babi Tripneustes gratilla. Metode yang digunakan dalam penelitian ini yaitu menggunakan metode eksploratif. Parameter uji yang digunakan adalah parameter objektif yang meliputi analisa profil asam amino, pengujian

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Sergeeva, N. P. "The dynamics of the liver weight and liver indices in the course of gonad maturation of gadid species on Eastern Kamchatka." Researches of the aquatic biological resources of Kamchatka and the North-West Part of the Pacific Ocean, no. 59 (September 18, 2021): 5–26. http://dx.doi.org/10.15853/2072-8212.2020.59.5-26.

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Longterm data on the liver weight, hepatosomatic (HSI) and gonadosomatic (GSI) indices of walleye pollock, Pacific cod and saffron cod are analyzed on Eastern Kamchatka in seasonal aspect and in the course of gonad maturation. Individual values of the indices extensively vary and depend on the fish body length, season and stage of gonad maturity. The dynamics of the HSI is agree to the dynamics of the GSI during the year and depending on gonad maturity. The maximum values of the HSI are typical for walleye pollock and Pacific cod individuals with the gonads of the III stage of maturity. The ma

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Lucas, Cathy H., and Adam J. Reed. "Gonad morphology and gametogenesis in the deep-sea jellyfish Atolla wyvillei and Periphylla periphylla (Scyphozoa: Coronatae) collected from Cape Hatteras and the Gulf of Mexico." Journal of the Marine Biological Association of the United Kingdom 90, no. 6 (2009): 1095–104. http://dx.doi.org/10.1017/s0025315409000824.

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Observations on gonad morphology and the structure of ovaries and testes of the coronate scyphozoans Atolla wyvillei and Periphylla periphylla are described based on samples collected from the Gulf of Mexico and Cape Hatteras (north-western Atlantic). In A. wyvillei, gonads of distinguishable sex were observed in medusae as small as 17 mm bell diameter (BD). Spermatogenesis occurred within follicles (average 366 × 254 μm) that were evenly distributed throughout the gonad. Oocytes in different stages of development were observed in all the females with gonads. Oocytes arise from the gastrodermi

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