Relevant bibliographies by topics / Gpt3 / Dissertations / Theses
To see the other types of publications on this topic, follow the link: Gpt3.

Dissertations / Theses on the topic 'Gpt3'

Author: Grafiati
Published: 5 June 2025
Last updated: 2 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Gpt3.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Ellis, Miriam A. "Processing and trafficking of GP63 in Leishmania mexicana GPI8 mutants." Thesis, University of Glasgow, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269507.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Martino, Michael. "A Potential Role for Hepatic GPT2 in Endurance Exercise Performance." Thesis, Southern Illinois University at Edwardsville, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10808503.

Full text
Abstract:
<p> Alanine has long been recognized as an important substrate for hepatic gluconeogenesis through the glucose-alanine (Cahill) cycle which plays an important role in the maintenance of euglycemia during times of caloric deficiency. The Cahill cycle involves the transamination of pyruvate by the amino group of glutamate, producing &alpha;-ketoglutarate and alanine. Alanine formed in skeletal muscle during exercise can be sent to the liver where it is used to produce glucose and safely remove the <i>NH</i><sub>3+</sub> as urea. This process is catalyzed by the glutamic-pyruvic transaminase (GPT
APA, Harvard, Vancouver, ISO, and other styles
3

Konno, Adriana Yumi de Camargo [UNIFESP]. "Peptideos derivados da gp43 de Paracoccidioides brasiliensis inibem a fagocitose." Universidade Federal de São Paulo (UNIFESP), 2008. http://repositorio.unifesp.br/handle/11600/21921.

Full text
Abstract:
Made available in DSpace on 2015-12-06T23:45:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2008<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Paracoccidioidomicose (PCM) é uma doença granulomatosa sistêmica causada pelo fungo dimórfico térmico Paracoccidioides brasiliensis. O principal antígeno desse fungo é uma glicoproteína de 43-KDa. Gp43 possui diferentes funções: participa do mecanismo de evasão durante a instalação da infecção primária e estimula formação de granuloma in vitro, apre
APA, Harvard, Vancouver, ISO, and other styles
4

El, Haddad Marina. "Approche pharmacologique dans la thérapie cellulaire : rôle de l'acide rétinoïque dans la survie et la différenciation des myoblastes humains." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTT003.

Full text
Abstract:
Les cellules satellites sont considérées comme de véritables cellules souches du muscle squelettique. Une fois transplantées dans un muscle hôte, les myoblastes, cellules filles des cellules satellites, sont capables de fusionner avec les fibres musculaires existantes, permettant ainsi de modifier de façon permanente le muscle receveur. La greffe des cellules satellites est donc une des thérapies dans la lutte contre les maladies musculaires dégénératives ou myopathies. Malheureusement les premiers essais cliniques sont décevants compte tenu en partie d’une mortalité massive au sein des myobla
APA, Harvard, Vancouver, ISO, and other styles
5

Ogusuku, Soraya. "Avaliação da resposta linfoproliferativa de pacientes com paracoccidioidomicose e indivíduos curados a antígenos de Paracoccidioides brasiliensis: filtrado de cultura, gp43 e gp43 tratada com metaperiodato." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5133/tde-29042009-145526/.

Full text
Abstract:
A Paracoccidioidomicose é micose sistêmica causada pelo fungo Paracoccidioides brasiliensis, endêmico na América Latina, especialmente Brasil. Para melhor avaliarmos a resposta imune celular frente a diferentes componentes do fungo, como gp43, considerada o antígeno imunodominante de P. brasiliensis, filtrado de cultura livre de gp43 (Filtrado), e gp43 tratada com metaperiodato (meta), utilizamos os ensaios de linfoproliferação e ELISA para detecção das citocinas IL-4, IL-10, IL-12 e IFN-. Os resultados com relação à gp43 corroboram dados da literatura e de nosso laboratório demonstrando que g
APA, Harvard, Vancouver, ISO, and other styles
6

Petroni, Tatiane Ferreira. "Obtenção de gp43 de Paracoccidioides brasiliensis recombinante em Escherichia coli e produção de anticorpos policlonais para gp43 em galinhas poedeiras imunizadas com vacina de DNA." Universidade Estadual de Londrina. Centro de Ciências Biológicas. Programa de Pós-Graduação em Patologia Experimental, 2009. http://www.bibliotecadigital.uel.br/document/?code=vtls000149274.

Full text
Abstract:
A paracoccidioidomicose (PCM) é uma micose sistêmica, endêmica na América Latina, causada pelo fungo termodimórfico Paracoccidioides brasiliensis (Pb). É considerada a oitava causa de mortes por doenças infecciosas e parasitárias no Brasil. Os testes imunológicos são utilizados tanto para fins de diagnóstico, acompanhamento do tratamento e epidemiologia da PCM. A glicoproteína de 43 kDa (gp43) que é o principal antígeno utilizado nos ensaios imunológicos, possui epítopos carboidrato que podem levar a reações cruzadas com soros de pacientes com histoplasmose e Doença de Jorge Lobo. A produção d
APA, Harvard, Vancouver, ISO, and other styles
7

Skinner, Anita Claire. "Molecular determinants of virulence in Leishmania mexicana." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337830.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Elson, Lynne Hilary. "Characterisation of Gp63 and its relevance to immunodiagnosis of visceral leishmaniasis." Thesis, University of Liverpool, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316608.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

REGO, NUBIA CORREIA DO. "LONGEVITY AND EMPLOYEE RETENTION IN COMPANIES GREAT PLACE TO WORK (GPTW)." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2014. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=23518@1.

Full text
Abstract:
Este trabalho analisou a relação entre as melhores empresas para trabalhar, a retenção de pessoas e a longevidade organizacional, isto é, se as empresas mais longevas são as melhores empresas para trabalhar e que mais apresentam características de atração e retenção de seus profissionais. Foi realizada uma pesquisa exploratória, explicativa e descritiva com base em dados secundários do ranking Great Place to Work (GPTW) brasileiro de 2013. A abordagem quantitativa focou um universo de 327 empresas nacionais, do qual foi identificada uma amostra de 70 grandes empresas premiadas no ranking, subd
APA, Harvard, Vancouver, ISO, and other styles
10

Bunztman, Adam, Benjamin Vincent, Harsha Krovi, Shaun Steele, and Jeffrey Frelinger. "The LCMV gp33-specific memory T cell repertoire narrows with age." BioMed Central, 2012. http://hdl.handle.net/10150/610159.

Full text
Abstract:
BACKGROUND:The memory response to LCMV in mice persists for months to years with only a small decrease in the number of epitope specific CD8 T cells. This long persistence is associated with resistance to lethal LCMV disease. In contrast to studies focused on the number and surface phenotype of the memory cells, relatively little attention has been paid to the diversity of TCR usage in these cells. CD8+ T cell responses with only a few clones of identical specificity are believed to be relatively ineffective, presumably due to the relative ease of virus escape. Thus, a broad polyclonal respons
APA, Harvard, Vancouver, ISO, and other styles
11

Valsechi, Marina Curado [UNESP]. "Análise funcional do gene GPC3 em carcinoma renal de células claras." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/127546.

Full text
Abstract:
Made available in DSpace on 2015-09-17T15:24:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-08-14. Added 1 bitstream(s) on 2015-09-17T15:48:22Z : No. of bitstreams: 1 000846657_20170814.pdf: 327624 bytes, checksum: 7ef206fbad82624c5b13293820611818 (MD5) Bitstreams deleted on 2017-08-18T12:37:00Z: 000846657_20170814.pdf,. Added 1 bitstream(s) on 2017-08-18T12:37:50Z : No. of bitstreams: 1 000846657.pdf: 655179 bytes, checksum: a3015379981e83babb9b5ebdeb18615d (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>GPC3 (Glipican-3) é membro de uma família de prot
APA, Harvard, Vancouver, ISO, and other styles
12

Valsechi, Marina Curado. "Análise funcional do gene GPC3 em carcinoma renal de células claras /." São José do Rio Preto, 2013. http://hdl.handle.net/11449/127546.

Full text
Abstract:
Orientador: Paula Rahal<br>Banca: Ana Carolina Gomes Jardim<br>Banca: Wilson Araújo da Silva Júnior<br>Banca: Ana Elizabete Silva<br>Banca: Sônia Maria Oliani<br>Resumo: GPC3 (Glipican-3) é membro de uma família de proteoglicano de heparina sulfatada (HSPG). O GPC3 pode atuar controlando a migração celular, regulação negativa do crescimento celular e indução de apoptose. Esse gene é relatado por estar hipoexpresso em vários tipos de cânceres, o que pode resultar no crescimento celular descontrolado e contribuir para o fenótipo maligno de alguns tumores. O objetivo desse estudo foi analisar o m
APA, Harvard, Vancouver, ISO, and other styles
13

Paee, Furzani. "Photosynthetic acclimation to lower light intensity in Arabidopsis thaliana." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/photosynthetic-acclimation-to-lower-light-intensity-in-arabidopsis-thaliana(39ab9c6f-f1f2-463c-93c2-32210b7d8f4e).html.

Full text
Abstract:
Photoacclimation is a process by which photosynthetic capacity is regulated in response to environmental adjustments in terms of light regime. Photoacclimation is essential in determining the photosynthetic capacity to optimize light use and to avoid potentially damaging effects. Previous work in our laboratory has identified a gene, gpt2 (At1g61800) that is essential for plants to acclimate to an increase in growth irradiance. Furthermore, we observed that the accession Columbia-0 (Col-0) is unable to respond to increases in light. Therefore, a Quantitative Trait Locus (QTL) mapping analysis
APA, Harvard, Vancouver, ISO, and other styles
14

Kennedy, Christopher Brandon. "GPT-Free Sensitivity Analysis for Reactor Depletion and Analysis." Thesis, North Carolina State University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3710730.

Full text
Abstract:
<p> Introduced in this dissertation is a novel approach that forms a reduced-order model (ROM), based on subspace methods, that allows for the generation of response sensitivity profiles without the need to set up or solve the generalized inhomogeneous perturbation theory (GPT) equations. The new approach, denoted hereinafter as the generalized perturbation theory free (GPT-Free) approach, computes response sensitivity profiles in a manner that is independent of the number or type of responses, allowing for an efficient computation of sensitivities when many responses are required. Moreover, t
APA, Harvard, Vancouver, ISO, and other styles
15

Ferreira, Karen Spadari. "Modulação da ativação de células dentríticas por Paracoccidioides brasiliensis." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-21052009-094918/.

Full text
Abstract:
A paracoccidioidomicose (PCM) é uma micose sistêmica, endêmica na América Latina, causada pelo fungo dimórfico térmico Paracoccidioides brasiliensis (P. brasiliensis), cujo principal componente antigênico é a glicoproteína de 43 kDa (gp43). Diferentes formas clínicas podem ser desenvolvidas e estão diretamente associadas com vários graus de depressão da resposta imune celular. Considerando a importância das células dendríticas na interação dos sistemas imune inato e adaptativo, e na ativação de células T \"naive\", no presente trabalho estudamos se células dendríticas interagem com leveduras d
APA, Harvard, Vancouver, ISO, and other styles
16

Qi, Xiang, and 祁翔. "The role of glutathione peroxidase 3 (GPx3) : bridging graft injury and tumor invasiveness." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206452.

Full text
Abstract:
Background and Objective: Severe inflammation resulted from small-for-size liver graft injury provides favorable environment for tumor growth. The oxidative stress not only accelerates the inflammatory response, but also stimulates the proliferation of cancer cells. Therefore, attenuating oxidative stress after liver surgery may not only ameliorate liver injury, but also suppress tumor growth and metastasis. Glutathione peroxidase 3 (GPx3) is an anti-oxidant which has been reported to be down-regulated in several types of cancer. Here, we aimed to investigate the clinical significance of GPx
APA, Harvard, Vancouver, ISO, and other styles
17

Soerensen, Tine Kring. "Cloning and characterisation of a gpt gene from Aspergillus niger." Thesis, University of Nottingham, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364397.

Full text
APA, Harvard, Vancouver, ISO, and other styles
18

Maurel, Marion. "Les microARNs régulateurs de l’expression génique du Glypican-3 dans le Carcinome Hépatocellulaire." Thesis, Bordeaux 2, 2012. http://www.theses.fr/2012BOR21945/document.

Full text
Abstract:
Le Glypican-3 (GPC3) est surexprimé dans 72% des carcinomes hépatocellulaire (CHC). C’est un co-récepteur membranaire du récepteur WNT, qui appartient à la famille des protéoglycanes à sulfates d'héparane. L'objectif général de ma thèse vise à étudier les mécanismes de régulation post-transcriptionnelle de l’expression du GPC3 dans le CHC. Pour cela, j’ai développé un test fonctionnel qui m’a permis de cribler une bibliothèque de 876 microARNs humains. Ceci a conduit à l’identification de 5 microARNs régulateurs de l’expression de l’ARNm codant pour le GPC3 via sa région 3’ non traduite (NT).
APA, Harvard, Vancouver, ISO, and other styles
19

Santos, Adriana Magalhães. "Imunoproteção induzida por células dendríticas pulsadas com peptídeo P10 derivado da gp43 de Paracoccidioides brasiliensis." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-17122010-141513/.

Full text
Abstract:
Paracoccidioidomicose (PCM) é uma micose sistêmica causada pelo fungo Paracoccidioides brasiliensis e é considerada a 10º causa de morte dentre doenças infecciosas e parasitárias no Brasil. As células dendríticas (DCs) são as mais eficientes na apresentação de antígenos, e sendo de 100 a 1000 vezes mais eficientes que um adjuvante não específico. P10, motivo específico de 15 aminoácidos derivado da gp43 excretada pelo fungo, é reconhecido por linfócitos T, direciona para resposta Th1 e confere proteção no modelo experimental. Nesse sentido, analisamos a capacidade de DCs pulsadas com P10 em a
APA, Harvard, Vancouver, ISO, and other styles
20

Ipinmoroti, Ayodeji Oludare. "Effects of Lactobacillus rhamnosus MRS6AN on Intestinal GPAT3 pathway involved in the lipid transport in enterocytes." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etd/3273.

Full text
Abstract:
Accumulation of triglyceride (TG) in enterocytes of the small intestine follows two specific absorption pathways: the monoacylglycerol acyltransferase pathway (MGAT) and glycerol acyltransferase pathway (GPAT), the latter (GPAT) is usually found in the small intestine. In this study, we investigated the effects of Lactobacillus rhamnosus MRS6AN, an isolate from “amabere amaruranu” a Kenyan traditional cultured milk, on triglyceride accumulation and expression of GPAT3, I-FABP, MTP and NPC1L1 in Caco-2 cell enterocyte model. Intracellular triglyceride level (TG) of Caco2 cells was significantly
APA, Harvard, Vancouver, ISO, and other styles
21

Han, Shuanglin. "Inhibition of glypican 3 facilitates hepatocellular carcinoma cells to acquire cancer stem cell phenotype by activating epithelial mesenchymal transition pathway." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/26929.

Full text
Abstract:
Hepatocellular carcinoma (HCC) is the most common primary liver cancer. In 2012, 782,000 HCC patients were diagnosed worldwide, and among them 746,000 died. Currently, HCC is the 6th most common and the 3rd most fatal cancer globally. Patients with the advanced HCC have few treatment options. Sorafenib is the first line systemic therapy but it only prolongs patients’ survival time by two months. As a second line therapy, regorafenib could be used to treat the patients with sorafenib resistance, however, this agent also has limited efficacy as it only extends patients survival by <3 months. Des
APA, Harvard, Vancouver, ISO, and other styles
22

Altoé, Ellen Cristina Felix. "Avaliação da relevância da gp63 de Leishmania braziliensis e Leishmania infantum na interação com o hospedeiro invertebrado." reponame:Repositório Institucional da FIOCRUZ, 2013. https://www.arca.fiocruz.br/handle/icict/14373.

Full text
Abstract:
Made available in DSpace on 2016-05-19T13:16:21Z (GMT). No. of bitstreams: 2 ellen_altoe_ioc_mest_2013.pdf: 1397353 bytes, checksum: 107b103e24982f28206bdb6e9749cd60 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2013<br>Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil<br>A gp63, metalopeptidase altamente abundante na superfície de Leishmania, contribui para uma infinidade de funções bem estabelecidas na interação deste parasito com o hospedeiro mamífero. No entanto, apesar desta molécula ser abundantemente expres
APA, Harvard, Vancouver, ISO, and other styles
23

Albano, Ana Paula Neuschrank. "Paracoccidioides brasiliensis: utilização de animais como sentinelas para presença do fungo no Rio Grande do Sul, Brasil." Universidade Federal de Pelotas, 2012. http://repositorio.ufpel.edu.br/handle/ri/2493.

Full text
Abstract:
Made available in DSpace on 2014-08-20T14:37:52Z (GMT). No. of bitstreams: 1 tese_ana_albano.pdf: 1506402 bytes, checksum: 95dde41b6fa23dd1ab15dcbaaea21132 (MD5) Previous issue date: 2012-12-12<br>The paracoccidioidomycosis (PCM) is one of the most important systemic mycoses in Latin America, especially in Brazil. Although the Rio Grande do Sul is considered endemic area of the disease, there are few studies on the ecology of Paracoccidioides brasiliensis in the state. In this sense, the study aimed to detect infection by P. brasiliensis in animals using them as sentinels for detection of
APA, Harvard, Vancouver, ISO, and other styles
24

Gardizani, Taiane Priscila. "Avaliação da expressão de receptores celulares e da produção de citocinas e eicosanoides por neutrófilos humanos em resposta a glicoproteína gp43 do Paracoccidioides brasiliensis." Botucatu, 2019. http://hdl.handle.net/11449/183160.

Full text
Abstract:
Orientador: Luciane Alarcão Dias-Melicio<br>Resumo: A paracoccidioidomicose (PCM) é uma doença granulomatosa sistêmica, prevalente na América Latina, que tem por agentes etiológicos diferentes espécies de Paracoccidioides. Entre eles encontra-se o Paracoccidioides brasiliensis (P. brasiliensis), espécie composta por um complexo de agrupamentos geneticamente isolados, classificados como espécies filogenéticas: S1, PS2, PS3 e PS4. O P. brasiliensis possui distribuído pela parede fúngica e dentro de vesículas citoplasmáticas uma glicoproteína de 43KDa, a gp43. Esta molécula é considerada como o p
APA, Harvard, Vancouver, ISO, and other styles
25

Monteiro, Daniela Aparecida [UNESP]. "Propriedades elétricas de materiais híbridos de Sílica/orgânico à base de GPTS/TEOS preparados pelo método sol-gel." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/134128.

Full text
Abstract:
Made available in DSpace on 2016-02-05T18:29:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-05-22. Added 1 bitstream(s) on 2016-02-05T18:33:52Z : No. of bitstreams: 1 000856758_20170610.pdf: 92355 bytes, checksum: d68984beb418835cabad355cb1c998f2 (MD5) Bitstreams deleted on 2017-06-19T16:12:32Z: 000856758_20170610.pdf,. Added 1 bitstream(s) on 2017-06-19T16:13:17Z : No. of bitstreams: 1 000856758.pdf: 715358 bytes, checksum: c8ed7fae87732dccc9b310dd9be9df16 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Materiais híbridos de Sílica/Orgânico também
APA, Harvard, Vancouver, ISO, and other styles
26

Monteiro, Daniela Aparecida. "Propriedades elétricas de materiais híbridos de Sílica/orgânico à base de GPTS/TEOS preparados pelo método sol-gel /." Rio Claro, 2015. http://hdl.handle.net/11449/134128.

Full text
Abstract:
Orientador: Fábio Simões de Vicente<br>Banca: Alexandre Mesquita<br>Banca: Ubirajara Pereira Rodrigues Filho<br>Resumo: Materiais híbridos de Sílica/Orgânico também conhecidos como Silicatos Modificados Organicamente (ORMOSIL) são muito estudados devido à variedade de alcóxidos de silício funcionalizados com moléculas orgânicas ligadas covalentemente ao silício (epóxi, vinil, amina, fenil, etc). Neste trabalho foram investigadas as propriedades elétricas de materiais híbridos de Sílica/orgânico à base de GPTS (3-glicidoxipropiltrimetoxisilano) e TEOS (tertraetilortosilicato), preparadas pelo p
APA, Harvard, Vancouver, ISO, and other styles
27

Pham-Hung, d'Alexandry d'Orengiani Anne-Laure. "The accessory glycoprotein gp3 of canine Coronavirus type 1 : investigations of sequence variability in feline host and of the basic features of the different variants." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA114831/document.

Full text
Abstract:
Les différents génotypes de Coronavirus canins (CCoV-I/II) et félins (FCoV-I/II) sont phylogénétiquement proches, suggérant des transmissions inter-espèces entre chiens et chats. Lors d’analyses de séquences menées sur des chats infectés, des souches félines atypiques ont pu être mises en évidence, contenant un gène S de type FCoV-I, un gène N de type CCoV-I, ainsi que la présence du gène ORF3, spécifique à CCoV-I. Dans ces souches, le gène ORF3 est présent avec une ou deux délétions toujours identiques, conduisant à la synthèse de protéines tronquées gp3-Δ1 et gp3-Δ2. Les délétions de protéin
APA, Harvard, Vancouver, ISO, and other styles
28

Ueda, Tatsuki. "Non-clinical efficacy, safety, and stable clinical cell processing of iPSC-derived anti-GPC3 CAR-expressing NK/ILC cells." Kyoto University, 2020. http://hdl.handle.net/2433/253488.

Full text
APA, Harvard, Vancouver, ISO, and other styles
29

Al-Kadhimi, Staffan, and Paul Löwenström. "Identification of machine-generated reviews : 1D CNN applied on the GPT-2 neural language model." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-280335.

Full text
Abstract:
With recent advances in machine learning, computers are able to create more convincing text, creating a concern for an increase in fake information on the internet. At the same time, researchers are creating tools for detecting computer-generated text. Researchers have been able to exploit flaws in neural language models and use them against themselves; for example, GLTR provides human users with a visual representation of texts that assists in classification as human-written or machine-generated. By training a convolutional neural network (CNN) on GLTR output data from analysis of machine-gen
APA, Harvard, Vancouver, ISO, and other styles
30

Wang, Bin. "ICT and economic growth : a dynamic non-parametric approach." Thesis, Loughborough University, 2010. https://dspace.lboro.ac.uk/2134/7248.

Full text
Abstract:
One of important issues of the policymakers is to improve output and/or productivity growth associated with information and communication technology (ICT) adoption, where total factor productivity (TFP) growth related with ICT in the 1990s appeared in the US but not in the UK (Jorgenson and Stiroh, 2000; Oliner and Sichel, 2000). The general agreement is that ICT can raise output and/or productivity growth via an increase in productivity growth in the ICT-producing sectors due to rapid technological progress, through capital deepening driven by high levels of investment in ICT equipments, and
APA, Harvard, Vancouver, ISO, and other styles
31

Stoidtner, Kirsten. "Funktionelle Charakterisierung der Orphan-G-Protein-gekoppelten Rezeptoren gpr3, gpr6 und gpr12 Ligandenidentifizierung, Expression und potentielle Bedeutung im Herz-Kreislauf-System /." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968337732.

Full text
APA, Harvard, Vancouver, ISO, and other styles
32

Pereira, Roney Henrique. "Estudo dos efeitos da terapia de scFv que mimetiza o antígeno gp43 de Paracoccidioides brasiliensis conjugado à nanocápsulas na paracoccidioidomicose experimental." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-10102016-153441/.

Full text
Abstract:
A paracoccidioidomicose (PCM) é uma micose sistêmica, endêmica na América Latina, com alta prevalência no Brasil. O agente etiológico da doença são fungos do gênero Paracoccidioides. A gp43 é o antígeno principal do Pb e tem sido demonstrado que camundongos imunizados com anticorpos monoclonais anti-gp43 (MAbs) (Ab1) induzem a cascata idiotípica, produzindo anticorpos anti-Id (Ab2) e anti-anti-Id (Ab3). Observou-se que todos os Mabs Ab2 inibiram (>90%) a ligação da gp43 ao Mab 17c (Ab1) sugerindo que estes Mabs anti-Id ligam-se ao parátopo do Mab Ab1, comprovando assim que os Mabs anti-Id obti
APA, Harvard, Vancouver, ISO, and other styles
33

Melo, Cynthia Farias Vieira de. "Análise do perfil de metilação dos genes THBS1, GPX3 e COX2 e identificação de H. pylori em amostras de câncer gástrico." Universidade Federal da Paraí­ba, 2013. http://tede.biblioteca.ufpb.br:8080/handle/tede/3645.

Full text
Abstract:
Made available in DSpace on 2015-04-01T14:16:01Z (GMT). No. of bitstreams: 1 ArquivoTotal.pdf: 1987821 bytes, checksum: 0557f7c6083cf4200e6fc6542c383ea7 (MD5) Previous issue date: 2013-05-16<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>Cancer is a disease with a high mortality rate in Brazil, including, stomach cancer is currently the fourth most common type of cancer worldwide, responsible for countless deaths. Its etiology is multifactorial, because studies suggest associations to various factors such as dietary habits, environmental factors, genetic and
APA, Harvard, Vancouver, ISO, and other styles
34

Zhang, Minze [Verfasser]. "Membrane Topology and Processing of Glycoprotein 3 (GP3) of Porcine Respiratory and Reproductive Syndrome Virus / Minze Zhang." Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1170814689/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
35

Teixeira, Aline Florencio. "Avaliação terapêutica da formulação vacinal baseada no peptídeo P10 derivado da glicoproteína (gp43) de Paracoccidioides brasiliensis e na flagelina de Salmonella (FliCd)." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-10022012-144710/.

Full text
Abstract:
Paracoccidioidomicose (PCM) é uma doença granulomatosa sistêmica causada pelo fungo dimórfico Paracoccidioides brasiliensis. Aproximadamente 10 milhões de pessoas que vivem em áreas endêmicas estão infectadas com P. brasiliensis e até 2% destas podem desenvolver a PCM. Períodos extensos de quimioterapia são necessários e problemas de recidiva da doença são frequentes. Vacinas anti-PCM ainda não estão disponíveis para uso em humanos, porém, nos últimos anos, testes em modelo animal mostram que estratégias vacinais são viáveis. Formulações vacinais baseadas na proteína gp43 e no peptídeo P10 es
APA, Harvard, Vancouver, ISO, and other styles
36

SCHWAAB, TOURLONIAS VERONIQUE. "Clonage et caracterisation du gene de la glutathion peroxydase plasmatique murine analyse de l'expression de gpx3 dans l'epididyme et dans le rein." Clermont-Ferrand 2, 1998. http://www.theses.fr/1998CLF22045.

Full text
Abstract:
L'acquisition et le maintien de la fertilite male sont des processus complexes encore loin d'etre elucides. Depuis son lieu d'elaboration, le testicule, jusqu'a l'ovule, le spermatozoide doit traverser les voies genitales males et femelles. C'est dans les premieres et principalement dans l'epididyme, que le spermatozoide est mature (acquisition de proprietes nouvelles lui permettant de feconder l'ovule). Non fecondant a la sortie du testicule, le spermatozoide devient fecondant apres son passage dans l'epididyme. En dehors des processus de maturation, le spermatozoide va trouver dans l'environ
APA, Harvard, Vancouver, ISO, and other styles
37

山田, 徹. "gptシャトルベクターを用いた突然変異検出系に関する研究". 京都大学 (Kyoto University), 2001. http://hdl.handle.net/2433/150923.

Full text
APA, Harvard, Vancouver, ISO, and other styles
38

Bjöörn, Anton. "Employing a Transformer Language Model for Information Retrieval and Document Classification : Using OpenAI's generative pre-trained transformer, GPT-2." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-281766.

Full text
Abstract:
As the information flow on the Internet keeps growing it becomes increasingly easy to miss important news which does not have a mass appeal. Combating this problem calls for increasingly sophisticated information retrieval methods. Pre-trained transformer based language models have shown great generalization performance on many natural language processing tasks. This work investigates how well such a language model, Open AI’s General Pre-trained Transformer 2 model (GPT-2), generalizes to information retrieval and classification of online news articles, written in English, with the purpose of
APA, Harvard, Vancouver, ISO, and other styles
39

Tao, Joakim, and David Thimrén. "Smoothening of Software documentation : comparing a self-made sequence to sequence model to a pre-trained model GPT-2." Thesis, Linköpings universitet, Institutionen för datavetenskap, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-178186.

Full text
Abstract:
This thesis was done in collaboration with Ericsson AB with the goal of researching the possibility of creating a machine learning model that can transfer the style of a text into another arbitrary style depending on the data used. This had the purpose of making their technical documentation appear to have been written with one cohesive style for a better reading experience. Two approaches to solve this task were tested, the first one was to implement an encoder-decoder model from scratch, and the second was to use the pre-trained GPT-2 model created by a team from OpenAI and fine-tune the mod
APA, Harvard, Vancouver, ISO, and other styles
40

Ouellet, Stéphane. "Études des mécanismes de régulation de la transcription des gènes humains P21CIP1/WAF1, GPC3 (GLYPICAN 3) et A-beta-PP (AMYLOID beta-PRECURSOR PROTEIN)." Thesis, Université Laval, 2010. http://www.theses.ulaval.ca/2010/27537/27537.pdf.

Full text
Abstract:
La connaissance des mécanismes qui contrôlent la transcription des gènes, comme l’interaction de facteurs protéiques au niveau des promoteurs, est essentielle pour comprendre plusieurs fonctions biologiques et espérer traiter certaines pathologies. Nous nous sommes attardés à mieux comprendre les mécanismes qui régulent trois gènes humains dont les patrons d’expression sont différents et qui sont impliqués dans diverses pathologies en tentant de mettre en parallèle les différences structurales et fonctionnelles entre ceux-ci. Les gènes AβPP et p21 sont exprimés chez l’adulte alors que GPC3 est
APA, Harvard, Vancouver, ISO, and other styles
41

Balaji, Chandra Sekhar Sinhadri [Verfasser]. "Expression and characterization of spike protein complexes Gp2/Gp3/Gp4 and Gp5/M of the Arterivirus / Sekhar Sinhadri Balaji Chandra." Berlin : Freie Universität Berlin, 2015. http://d-nb.info/1071843435/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
42

Silva, Larissa Pinheiro. "Vacinologia reversa: avaliação preliminar da resposta imunológica contra leishmaniose visceral no modelo experimental mesocricetus auratus imunizados com um peptídeo sintético da GP63 de leishmania major." Universidade Federal do Tocantins, 2017. http://hdl.handle.net/11612/981.

Full text
Abstract:
A leishmaniose é uma doença negligenciada causada por protozoários unicelulares do gênero Leishmania. De acordo com a Organização Mundial de Saúde, a doença é classificada em duas formas clínicas: leishmaniose tegumentar (LT) e leishmaniose visceral (LV). A LV, também conhecida como calazar, é a forma mais grave, sendo potencialmente fatal em indivíduos não tratados. Atualmente, um dos grandes desafios encontrados nos estudos acerca da crescente urbanização da leishmaniose visceral (LV), é o desenvolvimento de vacinas com elevada eficácia para induzir proteção contra infecção por Leishmania. N
APA, Harvard, Vancouver, ISO, and other styles
43

Jannuzzi, Grasielle Pereira. "Caracterização fenotípica de células dendríticas transfectadas com scFv obtido a partir de anticorpo monoclonal anti-idiotípico Ab2-β, que mimetiza o antígeno gp43 de Paracoccidioides brasiliensis." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-27032014-161621/.

Full text
Abstract:
A paracoccidioidomicose (PCM) é um a micose profunda de natureza granulomatosa, causada pelo fungo Paracoccidioides brasiliensis (P. brasiliensis) e que compromete preferencialmente o tecido pulmonar. O P. brasiliensis sintetiza várias substâncias, dentre estas, destaca-se a glicoproteína de 43 kDa (gp43), a qual é considerada o principal componente antigênico do fungo. Dada a importância da gp43, anticorpos monoclonais (Mabs) contra esta glicoproteína foram obtidos e posteriormente caracterizados. Baseado na hipótese da rede idiotípica, Jerne (1974) propôs que cada anticorpo, quando produzido
APA, Harvard, Vancouver, ISO, and other styles
44

Ishac, Nicole. "Comment deux lignées cellulaires stromales mésenchymateuses humaines récapitulent in vitro le microenvironnement hématopoïétique ? : Intérêt en ingénierie." Thesis, Tours, 2015. http://www.theses.fr/2015TOUR4038/document.

Full text
Abstract:
L’hématopoïèse se déroule dans un microenvironnement spécialisé appelé niche où les cellules souches hématopoïétiques (CSH) sont en contact étroit avec les cellules stromales mésenchymateuses. Cette interaction cellulaire associée à d’autres facteurs environnementaux, comme la présence des espèces réactives à l’oxygène, est cruciale pour la régulation des CSH normales, mais aussi leucémiques. Pour étudier ce microenvironnement, il est donc important de développer un modèle in vitro de niche humaine qui mime la physiologie in vivo. Nous avons choisi comme modèle deux lignées mésenchymateuses st
APA, Harvard, Vancouver, ISO, and other styles
45

Paciello, Maurício Oviedo. "Avaliação da resposta imunológica de uma formulação vacinal contra leishmaniose visceral constituída de peptídeos sintéticos da gp63 de leishmania major com predição para MHC-I/MHC-II." Universidade Federal do Tocantins, 2017. http://hdl.handle.net/11612/439.

Full text
Abstract:
A leishmaniose é considerada como uma das seis endemias prioritárias no mundo. Sua gravidade vai depender da espécie contaminante, podendo variar de uma lesão cutânea relativamente branda a uma infecção visceral que pode ser fatal na ausência de tratamento. Atualmente, um dos grandes desafios encontrados nos estudos acerca da crescente urbanização da leishmaniose visceral (LV), é o desenvolvimento de vacinas com elevada eficácia para induzir proteção contra infecção por Leishmania. Neste contexto, o presente estudo teve como objetivo avaliar a resposta imune humoral e celular de uma nova formu
APA, Harvard, Vancouver, ISO, and other styles
46

Jiang, Li. "Deletion and single nucleotide substitution at G:C are major mutations in the kidney of gpt delta transgenic mice after ferric nitrilotriacetate treatment." Kyoto University, 2008. http://hdl.handle.net/2433/135839.

Full text
APA, Harvard, Vancouver, ISO, and other styles
47

Tai, Nahla Omer Ahmed El. "Molecular approaches to direct diagnosis and characterization of Leishmania donovani in clinical isolates." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2003. http://dx.doi.org/10.18452/14845.

Full text
Abstract:
Die vorliegende Studie wurde in einer Gruppe von Dörfern im Ostsudan, Gedaref State, durchgeführt. Bei 100 Patienten mit der Verdachtsdiagnose Kala Azar- oder Post-Kala Azar- Leishmaniose war der Erregernachweis mit der PCR direkt in klinischen Proben, die auf Filterpapier aufgebracht worden waren, ohne vorherige Kultivierung erfolgreich. In dieser PCR wurden die ribosomalen, internal transcribed spacer (ITS1 & ITS2) amplifiziert, weil sie sehr variabel sind, eine klare Speziesidentifizierung gestatten und bei weiterführenden Analysen der PCR-Produkte auch der Nachweis stammspezifischer Unters
APA, Harvard, Vancouver, ISO, and other styles
48

Lagerkvist, Love. "Neural Novelty — How Machine Learning Does Interactive Generative Literature." Thesis, Malmö universitet, Fakulteten för kultur och samhälle (KS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-21222.

Full text
Abstract:
Every day, machine learning (ML) and artificial intelligence (AI) embeds itself further into domestic and industrial technologies. Interaction de- signers have historically struggled to engage directly with the subject, facing a shortage of appropriate methods and abstractions. There is a need to find ways though which interaction design practitioners might integrate ML into their work, in order to democratize and diversify the field. This thesis proposes a mode of inquiry that considers the inter- active qualities of what machine learning does, as opposed the tech- nical specifications of wha
APA, Harvard, Vancouver, ISO, and other styles
49

Coussens, Anna Kathleen. "Molecular regulation of calvarial suture morphogenesis and human craniofacial diversity." Thesis, Queensland University of Technology, 2007. https://eprints.qut.edu.au/16481/1/Anna_Coussens_Thesis.pdf.

Full text
Abstract:
This body of work is concerned with the genetics of craniofacial morphology and specifically with that of the cranial sutures which form fibrous articulations between the calvarial bones. The premature fusion of these sutures, known as craniosynostosis, is a common developmental abnormality and has been extensively utilised here as a tool through which to study the genetics of suture morphogenesis and craniofacial diversity. Investigations began with a search for polymorphisms associated with normal variation in human craniofacial characteristics. Denaturing High-Performance Liquid chro
APA, Harvard, Vancouver, ISO, and other styles
50

Coussens, Anna Kathleen. "Molecular regulation of calvarial suture morphogenesis and human craniofacial diversity." Queensland University of Technology, 2007. http://eprints.qut.edu.au/16481/.

Full text
Abstract:
This body of work is concerned with the genetics of craniofacial morphology and specifically with that of the cranial sutures which form fibrous articulations between the calvarial bones. The premature fusion of these sutures, known as craniosynostosis, is a common developmental abnormality and has been extensively utilised here as a tool through which to study the genetics of suture morphogenesis and craniofacial diversity. Investigations began with a search for polymorphisms associated with normal variation in human craniofacial characteristics. Denaturing High-Performance Liquid chromato
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the bibliographies on the topic 'Gpt3' for other source types:
Journal articles Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography