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1

Rebchuk, AD, BM Chaharyn, A. Alam, C. Hounjet, PA Gooderham, S. Yip, and S. Makarenko. "GP.6 The Impact of Brain Invasion on Intracranial Meningioma Grading." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 49, s1 (June 2022): S2. http://dx.doi.org/10.1017/cjn.2022.90.

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Background: In 2016, the WHO Classification of Brain Tumors included brain invasion as a standalone diagnostic criterion for grade 2 meningioma diagnosis. In this study we explored the impact of this change on the incidence and distribution of meningioma grades. Methods: All cases of meningiomas diagnosed from 2007-2020 at a tertiary care hospital were identified. The distribution of meningioma grades before (WHO 2007) and after (WHO 2016) the introduction of the 2016 WHO criteria were compared. Each case in the 2007 cohort was re-graded according to the 2016 criteria to determine the intra-class correlation (ICC) between grading criteria. Results: Of 814 cases, 532 (65.4%) were in the 2007 WHO cohort and 282 (34.6%) were in the 2016 WHO cohort. There were no differences in the distribution of meningioma grades between cohorts (p=0.11). Upon re-grading, 21 cases (3.9%) were changed. ICC between original and revised grade was 0.92 (95% CIs: 0.91-0.93). Amongst Grade 2 meningiomas with brain invasion, 75.8% had three or more atypical histologic features or an elevated mitotic index. Conclusions: Brain invasion alone has minimal impact on the incidence or distribution of specific meningioma grade tumors, likely due to cosegregation of grade elevating features.
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2

Spodick, David H., and A. Thomas Pezzella. "A Grade 6 Systolic Murmur." New England Journal of Medicine 341, no. 1 (July 1999): 27. http://dx.doi.org/10.1056/nejm199907013410105.

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3

Jin, Cao, Sean Hacking, Miglena K. Komforti, and Mansoor Nasim. "A Comparison of Death Domain-Associated Protein 6 in Different Endometrial Carcinomas Histotypes." Biomarker Insights 14 (January 2019): 117727191986489. http://dx.doi.org/10.1177/1177271919864892.

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Background: Death domain-associated protein 6 (DAXX) is involved in regulating apoptosis via subcellular localization. The presence of DAXX point mutations correlates well with loss of nuclear expression on immunohistochemistry (IHC). In this study, we sought to determine (1) whether DAXX expression pattern is the same across different uterine carcinoma subtypes, and (2) which uterine carcinomas show loss of nuclear DAXX IHC. Design: We studied 65 uterine carcinomas of the following histologic types: 30 endometrioid (12 FIGO [The International Federation of Gynecology and Obstetrics] grade 1, 12 FIGO grade 2, and 6 FIGO grade 3), 8 serous, 14 clear cell, and 13 undifferentiated/dedifferentiated type (UEC/DDEC). Nuclear DAXX IHC was assessed in each tumor and was graded semi-quantitatively as follows: 0% to 50%, 50% to 75%, and greater than 75% of lesional cells react. Results: A total of 61% (25/41) of high-grade carcinomas (FIGO grade 3, serous, clear cell, and UEC/DDEC]) showed retained DAXX nuclear staining in >75% of lesional cells, compared with only 4.2% (1/24) of the low-grade carcinomas (FIGO grades 1 and 2) ( P = .0001), where DAXX expression was cytoplasmic. In addition, in the 11 DDEC cases, all the differentiated components showed loss of nuclear DAXX compared with the undifferentiated components which retained nuclear DAXX expression. Conclusions: We demonstrate that loss of nuclear DAXX is present in low-grade endometrial carcinomas and the differentiated components in UEC/DDEC, but not in high-grade ones, suggesting DAXX’s role in tumor progression and its potential as a therapeutic target in high-grade endometrial carcinomas.
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Martinez, Antonio E., Li Lin, and Cherie H. Dunphy. "Grading of Follicular Lymphoma: Comparison of Routine Histology With Immunohistochemistry." Archives of Pathology & Laboratory Medicine 131, no. 7 (July 1, 2007): 1084–88. http://dx.doi.org/10.5858/2007-131-1084-goflco.

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Abstract Context.—Follicular lymphoma (FL) grading is based on the average number of large transformed cells in 10 neoplastic follicles at ×40 high-power field (×10–40 high-power field) examination (grade 1, 0–5 centroblasts per high-power field; grade 2, 6–15 centroblasts per high-power field; grade 3, >15 centroblasts per high-power field). Objective.—Since there may be significant interobserver variability, we analyzed the usefulness of immunohistochemical stains in grading FLs more reliably. Design.—Forty-three FLs initially graded by World Health Organization criteria (grade 1, 12; grade 2, 18; grade 3, 13) were reviewed and stained with CD3, CD20, Ki-67, CD30, CD68, PAX-5, and BCL-6. Retrospective review was performed for the average number of large cells, of large lymphoid cells, of large cells staining with CD3, CD20, BCL-6 (40 cases), and PAX-5, and of all cells staining with CD68, Ki-67, and CD30. Results.—By histologic review, 8 of 43 FLs had a significant grade change (4 cases upgraded and 4 cases downgraded). CD3 and CD30 stained only 0 to 3 large cells and 0 to 3 cells, respectively, in neoplastic follicles. CD68+ cells represented the large nonlymphoid cells. Increasing FL grades demonstrated increases in Ki-67+ cells. The original grade showed substantial agreement with CD20 and moderate agreement with PAX-5 and BCL-6. The original histologic grade agreed with immunohistochemical-based grade using 2 or more antibodies in 5 of 8 discordant cases (4 by CD20 or BCL-6 and PAX-5; 1 by CD20, PAX-5, and BCL-6). Conclusions.—Interobserver variability of histologic FL grading may be significant; we showed low-end “substantial agreement.” Immunohistochemical stains (ie, CD20, PAX-5, and BCL-6) may more reliably determine the number of large transformed cells in neoplastic follicles; Ki-67 staining correlates with higher FL grades. Immunohistochemical stains may be evaluated in clinical trials of FL patients to determine prognostic significance.
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5

Durham, Joanne. "In Closing . . .: Poetry Lesson Grade 6." Language Arts 85, no. 3 (January 1, 2008): 255. http://dx.doi.org/10.58680/la20086190.

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Hammoda, Rasha, Haitham Salah-ElDin, Nermin EL-Gharbawy, and Dina Ragab. "Krebs von den Lungen‐6, a promising marker in evaluating the severity of interstitial lung disease in Egyptian rheumatoid arthritis patients." Egyptian journal of Immunology 28, no. 4 (October 1, 2021): 241–49. http://dx.doi.org/10.55133/eji.280425.

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Krebs von den Lungen-6 (KL-6) is one of the mucins associated with interstitial lung disease. We aimed to assess the value of KL-6 as a marker for detecting the presence of interstitial lung disease in Egyptian rheumatoid arthritis patients and to evaluate its ability to assess severity in different grades of interstitial lung disease. The study included 89 rheumatoid arthritis patients; 64 patients with interstitial lung disease and 25 patients without interstitial lung disease. Serum levels of KL-6 were assessed using enzyme linked immunosorbent assay. Levels of KL-6 were higher in patients with interstitial lung disease compared to patients without interstitial lung disease (P< 0.001). KL-6 levels were significantly higher in grade 4 patients than those in grades 1 and 2. Also, KL-6 levels were significantly higher in grade 3 patients than those in grades 1 and 2. Kl-6 levels were also higher in grade 2 patients compared to grade 1 patients. Finally, no difference was observed between grade 4 patients and grade 3 patients. KL-6 levels were significantly higher in usual interstitial pneumonia pattern compared other patterns (P=0.015). In conclusion, KL-6 is a potential circulating biomarker that may have a substantial role in detecting the presence and evaluating the severity of interstitial lung disease among rheumatoid arthritis patients.
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7

Paul, Douglas J., William H. Nibbelink, and Hiram D. Hoover. "The Effects of Adjusting Readability on the Difficulty of Mathematics Story Problems." Journal for Research in Mathematics Education 17, no. 3 (May 1986): 163–71. http://dx.doi.org/10.5951/jresematheduc.17.3.0163.

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A 15-item story problem test was written at three different readability levels (below Grade 4, Grade 4 to Grade 6, above Grade 6) by two different methods (vocabulary control and sentence control). The six forms of the test were administered to over 1000 children in Grades 3 to 6. There was no effect of readability level on problem difficulty—not even the hint of an effect.
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8

Kudryachenko, O. P. "Age-related features of the development of motor abilities in boys in grades 5-9." Health-saving technologies, rehabilitation and physical therapy 1, no. 1 (November 26, 2019): 147–52. http://dx.doi.org/10.58962/hstrpt.2019.1.1.147-152.

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The purpose of the study is to determine the dynamics of age-related characteristics of the development of motor qualities in boys of grades 5–9. The study involved boys of grade 5 (n = 10), grade 6 (n = 10), grade 7 (n = 10), grade 8 (n = 10), grade 9 (n = 10). An analysis of the test results suggests that there are no statistically significant differences between boys of grades 5 and 6, except that boys of grades 6 show statistically significantly better results in tests for the manifestation of strength abilities. Statistically significant differences in the preparation of boys of grades 6 and 7 are observed only in the test “shuttle run 4x9 m”, which indicates the development of bone trapping and coordination abilities with age. Between boys of grades 7 and 8, statistically significant differences can be observed only in the test for the manifestation of strength forces. An analysis of the results of tests of grades 8 and 9 suggests that statistically significant differences are also observed in the 4x9 m shuttle test, which emphasizes the development of skeletal bone and coordination abilities with age.
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9

Yaseen, Ummer, Shazia Shah, and Aquisa Bashir. "Combination of platelet rich plasma and microneedling in the management of atrophic acne scars." International Journal of Research in Dermatology 3, no. 3 (August 24, 2017): 346. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20173691.

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<p class="abstract"><strong>Background:</strong> Acne scars have a lot of psychosocial implications, they are difficult to treat and can cause depression in the affected patient. The objective of the study was to assess the efficacy of combination of platelet rich plasma (PRP) injections and microneedling in the management of acne scars.</p><p class="abstract"><strong>Methods:</strong> Thirty-five patients with atrophic acne scars were enrolled and graded using Goodman and Baron qualitative grading. Platelet rich plasma injection and microneedling were done at 2-week interval alternatively for a total of 6 sessions of each. Acne scars were graded before and 6 months after starting the treatment. Patients own evaluation of improvement was also recorded.<strong></strong></p><p class="abstract"><strong>Results:</strong> A total of 12 patients had grade 4 acne scars, 8 (66.6%) improved to grade 2 and 4 (33.3%) improved to grade 3 scars. Out of 15 grade 3 scars, 8(53.3%) improved to grade 1, 7 (46.6%) improved to grade 2. 8 (100%) grade 2 patients improved to grade 1. All patients were highly satisfied with the results.</p><p><strong>Conclusions:</strong> This combination has shown good results in all grades of acne scars.</p>
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10

Kudryachenko, I. P. "Age-related features of the development of motor abilities in girls Grades 5-9." Health-saving technologies, rehabilitation and physical therapy 1, no. 1 (November 26, 2019): 143–46. http://dx.doi.org/10.58962/hstrpt.2019.1.1.143-146.

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The purpose of the study is to determine age-related characteristics of the development of motor abilities in girls of grades 5–9. The study involved girls of grade 5 (n = 10), grade 6 (n = 10), grade 7 (n = 10), grade 8 (n = 10) and grade 9 (n = 10). In girls of grades 5-6, according to the complex of all tests, statistically significant differences are observed only in the test for the manifestation of strength abilities. In girls of grades 6-7, positive changes are also observed in strength abilities, which emphasizes the development of strength qualities with age. Girls of grades 7-8 in a set of tests are statistically significantly different manifestation of coordination abilities. The analysis of average indicators of motor training of schoolchildren shows that in grades 8–9 there are no significant differences in the course of the development of motor abilities. In girls of grades 5–9, there is a statistically significant dynamics of physical fitness. The most growing indicators of strength and coordination of movements.
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11

Kirman, Joseph M., and Maria Unsworth. "Digital Data in the Grade 6 Classroom." Journal of Geography 91, no. 6 (November 1992): 241–46. http://dx.doi.org/10.1080/00221349208979104.

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12

Devi, Shameen, Michelle De Padua, and Iravathy Kalal. "Study of Histomolecular Classification of Glioma-Integrating Histology and Molecular Analysis in the Diagnosis of Brain Tumors." Indian Journal of Neurosurgery 07, no. 02 (August 2018): 129–34. http://dx.doi.org/10.1055/s-0038-1668469.

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Abstract Introduction The updated 2016 classification of gliomas incorporates well-established molecular parameters into the classification of diffuse gliomas, taking into account isocitrate dehydrogenase 1 (IDH1) mutation, α-thalassemia/mental retardation syndrome X-linked (ATRX) loss, and 1p/19q co-deletion. Aim and Objectives To study IDH1 and ATRX mutations in gliomas, 1p/19q co-deletion by fluorescent in situ hybridization (FISH) in oligodendroglioma, and to correlate IDH1, ATRX, and 1p/19q with tumor type and grade. Material and Methods Total 73 cases of gliomas were diagnosed on histology and graded as astrocytoma (grades 2–4), oligodendroglioma (grades 2–3), and oligoastrocytoma (grades 2–3) by two pathologists independently. IDH mutation and ATRX expression were analyzed using immunohistochemistry in all cases whereas 1p/19q co-deletion was studied using FISH in cases with oligodendroglioma and oligoastrocytoma morphology. Results Total 48 cases of astrocytoma, 9 cases of oligoastrocytoma, and 16 cases of oligodendroglioma were included. The maximum number of IDH1 mutation cases were seen in diffuse astrocytoma (7/10; 70%) as compared with anaplastic astrocytoma (5/15; 33.33%), glioblastoma multiforme (GBM) (3/23; 13.04%) grade II oligoastrocytoma (3/6; 50%), anaplastic oligoastrocytoma (2/3; 66.67%), and oligodendroglioma grade II (7/10; 70%). ATRX loss was seen in diffuse astrocytoma grade II (6/10; 60%), anaplastic astrocytoma (6/15; 40%), oligoastrocytoma grade II (2/6; 33.33%), and anaplastic oligoastrocytoma (1/3; 33.33%). 1p/19q co-deletion was seen in oligoastrocytoma (2/2; 100%), anaplastic oligoastrocytoma (1/2; 50%), oligodendroglioma (3/4; 75%), and anaplastic oligodendroglioma (1/3; 33.33%). Six of the seven cases with 1p/19q co-deletion also showed IDH1 mutation. One of seven 1p/19q co-deleted cases had loss of expression of ATRX. Conclusion Incorporation of IDH1 mutation, ATRX loss, and 1p/19q co-deletion molecular studies help in a more accurate diagnosis and classification of gliomas.
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França, Tamara S. F. A., Frederico F. N. França, R. Daniel Seale, Robert J. Ross, and Rubin Shmulsky. "Flexural properties of visually graded southern pine 2×4 and 2×6 structural lumber." BioResources 17, no. 1 (January 26, 2022): 1855–67. http://dx.doi.org/10.15376/biores.17.1.1855-1867.

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Flexural properties of visually graded southern pine structural lumber were evaluated. Several grade controlling characteristics were considered relative to bending properties and compared with current design values. A total of 751 southern pine lumber specimens were obtained from a broad spectrum of regions in the southeastern United States. Visually graded No. 2, nominally two inch thick specimens, in four and six inch widths, were obtained from commercial sawmills. All specimens were evaluated by a certified grader in the laboratory. Actual dimensions, weight, and moisture content (MC) were measured. Growth and manufacturing related characteristics were identified and classified into two categories: strength reducing characteristics (SRC) and grade reducing characteristics (GRC). Specific gravity (SG), bending modulus of elasticity (MOE), and modulus of rupture (MOR), were determined for each specimen. The presence of knots was identified as the most significant SRC; their presence had the most significant impact on SG, MOE and MOR. For GRC, specimens with knots, warp and specimens that fell into the category none, were significantly lower in SG, MOE and MOR. MOE and the allowable design bending strength values yielded in this study met the current design value criteria for both widths tested.
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Salgues, Betty, Thomas Graillon, Tatiana Horowitz, Olivier Chinot, Laetitia Padovani, David Taïeb, and Eric Guedj. "Somatostatin Receptor Theranostics for Refractory Meningiomas." Current Oncology 29, no. 8 (August 4, 2022): 5550–65. http://dx.doi.org/10.3390/curroncol29080438.

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Somatostatin receptor (SSTR)-targeted peptide receptor radionuclide therapy (PRRT) represents a promising approach for treatment-refractory meningiomas progressing after surgery and radiotherapy. The aim of this study was to provide outcomes of patients harboring refractory meningiomas treated by 177Lu-DOTATATE and an overall analysis of progression-free survival at 6 months (PFS-6) of the same relevant studies in the literature. Eight patients with recurrent and progressive WHO grade II meningiomas were treated after multimodal pretreatment with 177Lu-DOTATATE between 2019 and 2022. Primary and secondarily endpoints were progression-free survival at 6-months (PFS-6) and toxicity, respectively. PFS-6 analysis of our case series was compared with other similar relevant studies that included 86 patients treated with either 177Lu-DOTATATE or 90Y-DOTATOC. Our retrospective study showed a PFS-6 of 85.7% for WHO grade II progressive refractory meningiomas. Treatment was clinically and biologically well tolerated. The overall analysis of the previous relevant studies showed a PFS-6 of 89.7% for WHO grade I meningiomas (n = 29); 57.1% for WHO grade II (n = 21); and 0 % for WHO grade III (n = 12). For all grades (n = 86), including unknown grades, PFS-6 was 58.1%. SSTR-targeted PRRT allowed us to achieve prolonged PFS-6 in patients with WHO grade I and II progressive refractory meningiomas, except the most aggressive WHO grade II tumors. Large scale randomized trials are warranted for the better integration of PRRT in the treatment of refractory meningioma into clinical practice guidelines.
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G. Bautista, Romiro, Cynthia Grace T. Valdez, Eleanor G. Garingan, Jamina G. Camayang, Dennis Norfel P. Horlador, Jefferson N. Manait, and Elfie S. Reyes. "Individual Innovativeness of Pre-service Elementary Grade Teachers." American Journal of Educational Research 6, no. 6 (May 20, 2018): 617–20. http://dx.doi.org/10.12691/education-6-6-6.

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16

Conger, Andrew, Fan Zhao, Xiaowen Wang, Amalia Eisenberg, Chester Griffiths, Felice Esposito, Ricardo L. Carrau, Garni Barkhoudarian, and Daniel F. Kelly. "Evolution of the graded repair of CSF leaks and skull base defects in endonasal endoscopic tumor surgery: trends in repair failure and meningitis rates in 509 patients." Journal of Neurosurgery 130, no. 3 (March 2019): 861–75. http://dx.doi.org/10.3171/2017.11.jns172141.

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OBJECTIVEThe authors previously described a graded approach to skull base repair following endonasal microscopic or endoscope-assisted tumor surgery. In this paper they review their experience with skull base reconstruction in the endoscopic era.METHODSA retrospective review of a single-institution endonasal endoscopic patient database (April 2010–April 2017) was undertaken. Intraoperative CSF leaks were graded based on size (grade 0 [no leak], 1, 2, or 3), and repair technique was documented across grades. The series was divided into 2 epochs based on implementation of a strict perioperative antibiotic protocol and more liberal use of permanent and/or temporary buttresses; repair failure rates and postoperative meningitis rates were assessed for the 2 epochs and compared.RESULTSIn total, 551 operations were performed in 509 patients for parasellar pathology, including pituitary adenoma (66%), Rathke’s cleft cyst (7%), meningioma (6%), craniopharyngioma (4%), and other (17%). Extended approaches were used in 41% of cases. There were 9 postoperative CSF leaks (1.6%) and 6 cases of meningitis (1.1%). Postoperative leak rates for all 551 operations by grade 0, 1, 2, and 3 were 0%, 1.9%, 3.1%, and 4.8%, respectively. Fat grafts were used in 33%, 84%, 97%, and 100% of grade 0, 1, 2, and 3 leaks, respectively. Pedicled mucosal flaps (78 total) were used in 2.6% of grade 0–2 leaks (combined) and 79.5% of grade 3 leaks (60 nasoseptal and 6 middle turbinate flaps). Nasoseptal flap usage was highest for craniopharyngioma operations (80%) and lowest for pituitary adenoma operations (2%). Two (3%) nasoseptal flaps failed. Contributing factors for the 9 repair failures were BMI ≥ 30 (7/9), lack of buttress (4/9), grade 3 leak (4/9), and postoperative vomiting (4/9). Comparison of the epochs showed that grade 1–3 repair failures decreased from 6/143 (4.1%) to 3/141 (2.1%) and grade 1–3 meningitis rates decreased from 5 (3.5%) to 1 (0.7%) (p = 0.08). Prophylactic lumbar CSF drainage was used in only 4 cases (< 1%), was associated with a higher meningitis rate in grades 1–3 (25% vs 2%), and was discontinued in 2012. Comparison of the 2 epochs showed increase buttress use in the second, with use of a permanent buttress in grade 1 and 3 leaks increasing from 13% to 55% and 32% to 76%, respectively (p < 0.001), and use of autologous septal/keel bone as a permanent buttress in grade 1, 2, and 3 leaks increasing from 15% to 51% (p < 0.001).CONCLUSIONSA graded approach to skull base repair after endonasal surgery remains valid in the endoscopic era. However, the technique has evolved significantly, with further reduction of postoperative CSF leak rates. These data suggest that buttresses are beneficial for repair of most grade 1 and 2 leaks and all grade 3 leaks. Similarly, pedicled flaps appear advantageous for grade 3 leaks, while CSF diversion may be unnecessary and a risk factor for meningitis. High BMI should prompt an aggressive multilayered repair strategy. Achieving repair failure and meningitis rates lower than 1% is a reasonable goal in endoscopic skull base tumor surgery.
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Folarin, Bamidele Adepeju. "Comparison of Patterns of Word Association among Three Grades of Nigerian School Children." Psychological Reports 64, no. 3 (June 1989): 773–74. http://dx.doi.org/10.2466/pr0.1989.64.3.773.

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79 Nigerian primary school children in Grades 1, 3, and 6 associated to 48 categorizable Yoruba nouns which were randomly presented. They all significantly produced more paradigmatic than syntagmatic responses. Grade 6 gave the most superordinate, temporally, spatially, and functionally related responses. Grade 3 produced the most connotative responses, and Grade 1 emitted the most descriptive responses.
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Liebeskind, David S., Hamidreza Saber, Bin Xiang, Ashutosh P. Jadhav, Tudor G. Jovin, Diogo C. Haussen, Ronald F. Budzik, et al. "Collateral Circulation in Thrombectomy for Stroke After 6 to 24 Hours in the DAWN Trial." Stroke 53, no. 3 (March 2022): 742–48. http://dx.doi.org/10.1161/strokeaha.121.034471.

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Background and Purpose: Collaterals govern the pace and severity of cerebral ischemia, distinguishing fast or slow progressors and corresponding therapeutic opportunities. The fate of sustained collateral perfusion or collateral failure is poorly characterized. We evaluated the nature and impact of collaterals on outcomes in the late time window DAWN trial (Diffusion-Weighted Imaging or Computed Tomography Perfusion Assessment With Clinical Mismatch in the Triage of Wake-Up and Late Presenting Strokes Undergoing Neurointervention With Trevo). Methods: The DAWN Imaging Core Lab prospectively scored collateral grade on baseline computed tomography angiography (CTA; endovascular and control arms) and digital subtraction angiography (DSA; endovascular arm only), blinded to all other data. CTA collaterals were graded with the Tan scale and DSA collaterals were scored by ASITN grade (American Society of Interventional and Therapeutic Neuroradiology collateral score). Descriptive statistics characterized CTA collateral grade in all DAWN subjects and DSA collaterals in the endovascular arm. The relationship between collateral grade and day 90 outcomes were separately analyzed for each treatment arm. Results: Collateral circulation to the ischemic territory was evaluated on CTA (n=144; median 2, 0–3) and DSA (n=57; median 2, 1–4) before thrombectomy in 161 DAWN subjects (mean age 69.8±13.6 years; 55.3% women; 91 endovascular therapy, 70 control). CTA revealed a broad range of collaterals (Tan grade 3, n=64 [44%]; 2, n=45 [31%]; 1, n=31 [22%]; 0, n=4 [3%]). DSA also showed a diverse range of collateral grades (ASITN grade 4, n=4; 3, n=22; 2, n=27; 1, n=4). Across treatment arms, baseline demographics, clinical variables except atrial fibrillation (41.6% endovascular versus 25.0% controls, P =0.04), and CTA collateral grades were balanced. Differences were seen across the 3 levels of collateral flow (good, fair, poor) for baseline National Institutes of Health Stroke Scale, blood glucose <150, diabetes, previous ischemic stroke, baseline and 24-hour core infarct volume, baseline and 24-hour Alberta Stroke Program Early CT Score, dramatic infarct progression, final Thrombolysis in Cerebral Infarction 2b+, and death. Collateral flow was a significant predictor of 90-day modified Rankin Scale score of 0 to 2 in the endovascular arm, with 43.7% (31/71) of subjects with good collaterals, 30.8% (16/52) of subjects with fair collaterals, and 17.7% (6/34) of subjects with poor collaterals reaching modified Rankin Scale score of 0 to 2 at 90 days ( P =0.026). Conclusions: DAWN subjects enrolled at 6 to 24 hours after onset with limited infarct cores had a wide range of collateral grades on both CTA and DSA. Even in this late time window, better collaterals lead to slower stroke progression and better functional outcomes. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT02142283.
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Vaughn, Sharon, Jade Wexler, Audrey Leroux, Greg Roberts, Carolyn Denton, Amy Barth, and Jack Fletcher. "Effects of Intensive Reading Intervention for Eighth-Grade Students With Persistently Inadequate Response to Intervention." Journal of Learning Disabilities 45, no. 6 (April 21, 2011): 515–25. http://dx.doi.org/10.1177/0022219411402692.

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The authors report the effects of a yearlong, very small-group, intensive reading intervention for eighth-grade students with serious reading difficulties who had demonstrated low response to intervention (RTI) in both Grades 6 and 7. At the beginning of Grade 6, a cohort of students identified as having reading difficulties were randomized to treatment or comparison conditions. Treatment group students received researcher-provided reading intervention in Grade 6, which continued in Grade 7 for those with low response to intervention; comparison students received no researcher-provided intervention. Participants in the Grade 8 study were members of the original treatment ( N = 28) and comparison ( N = 13) conditions who had failed to pass a state-mandated reading comprehension test in both Grades 6 and 7. In Grade 8, treatment group students received a 50-minute, daily, individualized, intensive reading intervention in groups of two to four students per teacher. The results showed that students in the treatment condition demonstrated significantly higher scores than comparison students on standardized measures of comprehension (effect size = 1.20) and word identification (effect size = 0.49), although most continued to lack grade-level proficiency in reading despite 3 years of intervention. Findings from this study provide a rationale for intensive intervention for middle school students with severe reading difficulties.
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Carvalho, Fabrício Nunes, Armando Pereira Carneiro, Régis Resende Paulinelli, and Tanise Nunes Carvalho. "Neurophysiological classification of the Carpal Tunnel Syndrome." Acta Fisiátrica 14, no. 4 (December 9, 2007): 190–95. http://dx.doi.org/10.11606/issn.2317-0190.v14i4a102835.

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The aim of this study was to evaluate the clinical correlation of the neurophysiological scale of the Carpal Tunnel Syndrome (CTS). The hands were classified in 6 grades: minimum/grade 1 (comparative test / altered short segment, normal sensitive and motor conductions), mild/grade 2 (altered sensitive conduction, normal motor conduction), moderate/grade 3 (altered sensitive and motor conductions, normal sensitive amplitude), moderate/grade 4 (altered sensitive and motor conductions, low sensitive amplitude), severe/grade 5 (absent sensitive conduction, altered motor conduction) and extremely severe/grade 6 (absent sensitive and motor conductions). A prospective study was carried out in 400 hands with CTS. 56 hands (14%) were classified as grade 1,109 hands (27.3%) as grade 2, 129 hands (32.3%) as grade 3, 78 hands (19.5%) as grade 4, 22 hands (5.5%) as grade 5 and 6 hands (1.5%) as grade 6. There was a significant positive correlation (p < 0.01) between the neurophysiological scale of CTS and the patients’ ages, the duration of CTS, the frequency of reported classical CTS history and the frequency of night pain symptoms, paresthesia and numbness. Additionally, there was a significant positive correlation between the neurophysiological scale and the frequency of Tinel`s sign, hypoesthesia on the 2nd digit, weakness and hypotrophy of the thenar muscles.
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Kiełbasa, Marzena. "CREATIVE ATTITUDES OF 6-GRADE PRIMARY SCHOOL PUPILS." SOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference 2 (May 26, 2016): 389. http://dx.doi.org/10.17770/sie2016vol2.1403.

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Teachers’ recognition of the pupils’ creative potential is far from easy because of the complexity, ambiguity and multifaceted quality of the phenomenon of creativity. The activity of diagnosing pupils’ creative attitude calls for identifying the structure of their creative behaviour. Analysis of the data obtained in the study helped determine the level of the creative attitude of the pupils taking part in the study on the scale of heuristic and non-conformist behaviours.
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Evans, Sharon A., Phong T. Nguyen, Tim M. Barrett, Melissa K. Johnson, Panayiotis Doutis, Brandi Brobst, and Yousike Shinoda. "Chapter 6: Curriculum Effects in Seventh-Grade Pickleball." Journal of Teaching in Physical Education 18, no. 4 (July 1999): 444–54. http://dx.doi.org/10.1123/jtpe.18.4.444.

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Fu, You, Zan Gao, James C. Hannon, Ryan D. Burns, and Timothy A. Brusseau. "Effect of the SPARK Program on Physical Activity, Cardiorespiratory Endurance, and Motivation in Middle-School Students." Journal of Physical Activity and Health 13, no. 5 (May 2016): 534–42. http://dx.doi.org/10.1123/jpah.2015-0351.

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Background:This study aimed to examine the effect of a 9-week SPARK program on physical activity (PA), cardiorespiratory endurance (Progressive Aerobic Cardiovascular Endurance Run; PACER), and motivation in middle-school students.Methods:174 students attended baseline and posttests and change scores computed for each outcome. A MANOVA was employed to examine change score differences using follow-up ANOVA and Bonferroni post hoc tests.Results:MANOVA yielded a significant interaction for Grade × Gender × Group (Wilks’s Λ = 0.89, P < .001). ANOVA for PA revealed significant differences between SPARK grades 6 and 7 (Mean Δ = 8.11, P < .01) and Traditional grades 6 and 8 (Mean Δ = –6.96, P < .01). ANOVA also revealed greater PACER change for Traditional boys in grade 8 (P < .01) and SPARK girls in grade 8 (P < .01). There were significant interactions with perceived competence differences between SPARK grades 6 and 8 (Mean Δ = 0.38, P < .05), Enjoyment differences between SPARK grades 6 and 7 (Mean Δ = 0.67, P < .001), and SPARK grades 6 and 8 (Mean Δ = 0.81, P < .001).Conclusions:Following the intervention, SPARK displayed greater increases on PA and motivation measures in younger students compared with the Traditional program.
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Lin, Chuan Ju. "Concurrent and Separate Grade-Bundles with a Common Grade Sample Linking Designs for Vertical Scaling." Advanced Materials Research 108-111 (May 2010): 1348–53. http://dx.doi.org/10.4028/www.scientific.net/amr.108-111.1348.

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Mathematics tests of multiple-choice items for grades 2 through 6 were vertically scaled with the three-parameter logistic model using two different linking procedures: concurrent and separate by grade bundles. This research implements two designs under the separate by grade bundles procedure: grade bundle of two grades and grade bundle of three grades. All the items were calibrated using the 3-parameter logistic model (3-PLM) in the computer program, Bilog-MG with Grade 4 as the reference group. Under the separate grade-bundles method, the mean/sigma of the ability (i.e., θ) transformation method was applied to link the grade bundles. In general, the three scaling methods performed similarly in item difficulty and discrimination estimates, and in three score scale properties: grade-to-grade growth, grade-to-grade variability, and the separation of grade distributions. As a result, the grade-bundle of three grades design is preferable in the sense that it is more robust to the violation of the unidimensionality assumption over grades than the concurrent method and it yields less linking errors than the grade-bundle of two grades design.
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NICOLAS, VERONICA. "Utilization of Online Oral Reading Test in Determining the Reading Skills of the Grade 6 Pupils in English." Journal of World Englishes and Educational Practices 3, no. 4 (April 25, 2021): 01–05. http://dx.doi.org/10.32996/jweep.2021.3.4.1.

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Reading is every child’s foundation where great learning is involved and evidently proved one’s comprehension. Reading teachers play a vital role in assessing their pupils’ reading skills and administering intervention programs for learners’ reading development. This action research employed the Phil-IRI (Philippine Informal Reading Inventory) Oral Reading Test. This is an informal measure that assesses the pupils’ reading skills, both their reading speed and comprehension. It consists of graded reading passages from Grade I to Grade VI. Each graded passage is followed by 7 comprehension questions for Grades I-III and 8 comprehension questions for Grades IV-VI. The questions are categorized into three dimensions, namely literal, interpretive, and applied. Hence, reading speed and comprehension of the pupils will be classified into three levels as frustration, instructional and independent with the applied criteria given by the Phil-IRI. Furthermore, the results of the study exhibited that the ten groups of pupils demonstrated low reading performance in their oral reading test both in speed and comprehension. The struggle of the online oral reading test was evidently shown through the weak internet connection provided by the internet servers in the country. With this, the researcher designed a reading intervention program through reading remedial class during asynchronous class. This will be administered using the online platform and available reading resources for the enhancement of pupils’ reading skills amidst these trying times of global pandemic, where distance learning has been practised first in the public schools’ setting in the Philippines.
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Wang, Z. F., C. L. Briant, and K. S. Kumar. "Hydrogen Embrittlement of Grade 2 and Grade 3 Titanium in 6% Sodium Chloride Solution." CORROSION 54, no. 7 (July 1998): 553–60. http://dx.doi.org/10.5006/1.3284883.

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Mushawir, Mushawir, Harjuni Hasan, and Henny Magdalena. "Optimasi Konsumsi Fuel Dump Truck Terhadap Pengaruh Grade Jalan Pada Aktivitas Penambangan Pada PT. Pamapersada Nusantara Kecamatan Sangatta Utara Kabupaten Kutai Timur." MINERAL 7, no. 2 (November 15, 2022): 8–13. http://dx.doi.org/10.33019/mineral.v7i2.3338.

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The grade or slope of the road in a mining activity is certainly unavoidable. In addition to naturally following topographical contours, the shape of the mining pit is carried out from a high elevation leading to the lowest elevation following the slope level and the continuity of the excavation material makes the road should be made sloping. The high or low value of the road grade in addition to affecting the speed and travel time required by the unit, of course, also affects the level of fuel consumption. PT. Pamapersada Nusantara uses a conveyance unit with the HD Komatsu 785-7 type to move overburden material. Based on the results of the analysis, in the loaded condition, grade 2% uses 0.45 liters of fuel, 5% grades 0.77 liters, 6% grades 0.89 liters, 8% grades 1.09 liters and grades . While in the unloaded condition, grade 2% uses 0.19 liters of fuel, 5% grades 0.35 liters, 6% grades 0.4 liters, 8% grades 0.47 liters and 9% grades 0. 52 liters.
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Vaillancourt, Marie Claire, Alexandra Oliveira Paiva, Marie-Hélène Véronneau, and Thomas J. Dishion. "How Do Individual Predispositions and Family Dynamics Contribute to Academic Adjustment Through the Middle School Years? The Mediating Role of Friends’ Characteristics." Journal of Early Adolescence 39, no. 4 (May 29, 2018): 576–602. http://dx.doi.org/10.1177/0272431618776124.

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This study examined the mediating effect of friends’ characteristics (problem behavior and academic achievement) in the association between students’ background (family and individual factors) and later academic adjustment, as operationalized by problem behavior and academic achievement. We recruited 998 participants in three public middle schools and used three annual waves of data collection (Grades 6, 7, and 8). We found that students’ own academic achievement and problem bahvior are predictors of later adjustment. Friendship choices are identified as a mediation mechanism that contributes to consistent adjustment from the beginning to the end of middle school. Specifically, high-achieving students in Grade 6 tend to associate with high-achieving friends and are unlikely to associate with friends who exhibit problem behavior in Grade 7, which results in continued achievement in Grade 8. Associating with high-achieving friends in Grade 7 also mediated the link between adolescent problem behavior in Grade 6 and academic achievement by Grade 8. Friends’ characteristics in Grade 7 did not mediate the effect of any family factor measured in Grade 6. In general, our results suggest friendship selection is central to sustained success throughout the middle school years.
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Lee, Il Hwan, Do Hyun Kim, Jae-Sung Park, Sin-Soo Jeun, Yong-Kil Hong, and Sung Won Kim. "Cerebrospinal fluid leakage repair of various grades developing during endoscopic transnasal transsphenoidal surgery." PLOS ONE 16, no. 3 (March 26, 2021): e0248229. http://dx.doi.org/10.1371/journal.pone.0248229.

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Objectives We describe the strategy used to repair intraoperative leaks of various grades and define factors for preventing postoperative cerebrospinal fluid leakage (CSF) after surgery via the endoscopic endonasal transsphenoidal approach (EETA). Study design Retrospective chart review at a tertiary referral center. Methods Patients who underwent surgery via EETA from January 2009 to May 2020 were retrospectively reviewed. Intraoperative CSF leakage was graded 0–3 in terms of the dural defect size; various repairs were used depending on the grade. Results A total of 777 patients underwent 869 operations via EETA; 609 (70.1%) experienced no intraoperative CSF leakage (grade 0) but 260 (29.9%) did. Leakage was of grade 1 in 135 cases (15.5%), grade 2 in 83 (9.6%), and grade 3 in 42 (4.8%). In 260 patients with intraoperative CSF leakage, a buttress was wedged into the sellar defect site in 178 cases (68.5%) and a pedicled flap was placed in 105 cases (40.4%). Autologous fat (108 cases, 41.5%) and a synthetic dural substitute (91 cases, 35%) were used to fill the dead space of the sellar resection cavity. Postoperative CSF leakage developed in 21 patients: 6 of grade 1, 7 of grade 2, and 8 of grade 3. Buttress placement significantly decreased postoperative leakage in grade 1 patients (p = 0.041). In patients of perioperative leakage grades 2 and 3, postoperative CSF leakage was significantly reduced only when both fat and a buttress were applied (p = 0.042 and p = 0.043, respectively). Conclusion A buttress prevented postoperative CSF leakage in grade 1 patients; both fat and buttress were required by patients with intraoperative leakage of grades 2 and 3.
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Kiehn, Mark T. "Development of Music Creativity among Elementary School Students." Journal of Research in Music Education 51, no. 4 (December 2003): 278–88. http://dx.doi.org/10.2307/3345655.

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The purpose of this study was to compare the music improvisational creativity of students in Grades 2, 4, and 6. Randomly selected participants ( N = 89) were given two measures of creativity, the Vaughan Test of Musical Creativity and the Torrance Tests of Creative Thinking (figural form). Two independent judges scored responses on the Vaughan test to determine music improvisational creativity. A significant grade-level difference emerged for music creativity scores, with Grade 2 students scoring significantly lower than Grade 4 and 6 students. Results of the study may indicate a music creativity growth stage exists from Grade 2 to 4, followed by a developmental leveling (no significant change in test scores) between Grade 4 and Grade 6. There also were significant gender differences for music creativity test scores, with boys scoring higher than girls. Finally, a weak but statistically significant correlation was found between music creativity and figural creativity.
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31

Yamini K and Usha B. R. "Clinical assessment of corneal complications of manual small incision cataract surgery at tertiary care centre." Indian Journal of Clinical and Experimental Ophthalmology 9, no. 4 (December 15, 2023): 521–26. http://dx.doi.org/10.18231/j.ijceo.2023.099.

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: To assess corneal complications and visual outcome of manual small incision cataract surgery.: This study comprises of 227 patients in a tertiary care centre in Kolar district, who underwent MSICS were examined for corneal complications and visual outcome postoperatively on Day 1, 1 week, and at the end of 6 week also visual acuity (VA) assessment, anterior segment evaluation with slit lamp biomicroscopy, posterior segment evaluation using indirect ophthalmoscopy, and keratometry was done.227 participants were included in the study, of whom 138 (61%) were female and 89 (39%) were male. The maximum number of patients being in the age group of 61-70 (42.7%). OCTET grading was done for corneal edema patients and on post op Day 1, total 62 patients who had corneal edema in the study were graded according to OCTET classification, and 6 patients (9.6%) had grade 1, 17 patients (27.4%) had grade 2 and 39 patients (63%) had grade 3. At the end of 6 week postoperatively, 45 patients had clear cornea, and 5 patients (8%) had grade 1, 6 patients (9.5%) had grade 2, and 7 patients (11.1%) had grade 3, and 82.3% of patients had VA of 6/6 to 6/9 followed by 11% had 6/12 to 6/18 and 6.6% had 6/24 to 6/36.: Small incision cataract surgery is most cost-effective surgery if corneal endothelium is protected during surgery and will have early visual rehabilitation.
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Suryowati, Eny, Abd Rozak, and Eka Agustina Rizkiyati. "Awareness About Mathematical Patterns in MI Muhammadiyah 3 Jogoroto Jombang Students." Journal of Education and Learning Mathematics Research (JELMaR) 4, no. 1 (June 12, 2023): 52–62. http://dx.doi.org/10.37303/jelmar.v4i1.108.

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Awareness of patterns in this study is closely related to generalization. This awareness is the condition of someone who can know there is an order in the pattern, can mention the structure of the given pattern and can determine the next pattern. One of the basic skills in learning mathematics is generalization. This research is a descriptive quantitative research that aims to describe awareness of mathematical patterns in grades 4, 5 and 6 of MI Muhammadiyah 3 Jogoroto Jombang. The sample of this research was 89 students in grades 4, 5 and 6 of MI Muhammadiyah 3 Jogoroto Jombang. All students were given questions about number patterns and figure patterns and then conducted interviews. The results showed that students' awareness of number patterns was 80,65% for 4th grade , 95,83% for 5th grade and 97,06% for 6th grade . Meanwhile, students' awareness of figure patterns was 87,09% for 4th grade, 95,83% for 5th grade and 100% for 6th grade. Based on the results of this study, it can be seen that students in grades 4, 5 and 6 of MI Muhammadiyah 3 Jogoroto Jombang are already able to recognize pattern regularity, can mention the pattern structure and can determine the next pattern, which is limited in number. Students have not been able to determine the number of elements (structures) in the n-th pattern.
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Kim, Minhyun, Jiyoon Kim, Jungsoo Kim, Sanghyeok Park, Jihye Kim, Insun Kim, Inju Nam, and Kwang-Deog Moon. "Comparison of external, internal and chemical quality characteristics of 6-year-old red ginseng produced in punggi area by grade." Korean Journal of Food Preservation 29, no. 5 (August 2022): 701–14. http://dx.doi.org/10.11002/kjfp.2022.29.5.701.

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The purpose of this study was to analyze the correlation between the external, internal and chemical quality characteristics of 6-year-old red ginseng produced in punggi area. Red ginseng samples are graded as cheon (1st grade), ji (2nd grade), yang (3rd grade), gi (out of grade) by trained inspectors. External characteristics of red ginseng depend on weight, volume, density, length and color. Internal characteristics were expressed by length and occurrence ratio of inner white and inner cavity. Chemical characteristics were evaluated by crude saponin, ginsenoside (Rg1, Rb1, Rc), total sugar, acidic polysaccharide, and 50% ethanol extracts contents. Overall, this study showed that quality of external and internal characteristics was matched with grade, but chemical quality was not matched.
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Frisoli, Fabio A., Joshua S. Catapano, Dara S. Farhadi, Megan S. Cadigan, Candice L. Nguyen, Mohamed A. Labib, Visish M. Srinivasan, and Michael T. Lawton. "Spetzler-Martin Grade III Arteriovenous Malformations: A Comparison of Modified and Supplemented Spetzler-Martin Grading Systems." Neurosurgery 88, no. 6 (February 13, 2021): 1103–10. http://dx.doi.org/10.1093/neuros/nyab020.

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Abstract BACKGROUND The modified Spetzler-Martin (SM) grading system proposes that grade III arteriovenous malformation (AVM) subtypes are associated with variable microsurgical risks, with small AVMs (III−) having lower risk and medium/eloquent AVMs (III+) having higher risk. Adding patient age and AVM bleeding status and compactness to the SM grade produces a score – the supplemented SM (Supp-SM) grade – to more accurately assess preoperative risk. OBJECTIVE To compare the predictive power of the modified SM and Supp-SM grades for risk assessment in patients with grade III AVMs. METHODS Patients with SM grade III AVMs treated between 2011 and 2018 were retrospectively reviewed. Good outcomes were defined as modified Rankin Scale (mRS) scores ≤ 2 or unchanged/improved mRS scores (pre- vs postsurgery). RESULTS Of 102 patients with SM grade III AVMs, 59% had grade III− and 24% had grade III+ AVMs. Supp SM grade 6 and grade 7 AVMs accounted for 44% and 24%, respectively. Overall, 33% of patients worsened but outcomes did not significantly differ by SM III subtype. Neurological outcomes were associated with Supp-SM grade, with proportions of patients with worsening increasing from 0% with Supp-SM grade 4 AVMs to 54% with Supp-SM grade 7 AVMs. Analyses of factors associated with neurological worsening identified age &gt; 60 yr and Supp-SM grade 7 as significant. CONCLUSION Supp-SM grades were more predictive of microsurgical outcomes than modified SM grades for grade III AVMs, with a hard cutoff for acceptable surgical risk at Supp-SM grade 6. Supp-SM grading is a better decision-making tool than subtyping with the modified SM scale.
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Houlden, D. A., Chen Li, M. L. Schwartz, and Marko Katie. "Median Nerve Somatosensory Evoked Potentials and the Glasgow Coma Scale as Predictors of Outcome in Comatose Patients with Head Injuries." Neurosurgery 27, no. 5 (November 1, 1990): 701–8. http://dx.doi.org/10.1227/00006123-199011000-00006.

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Abstract Median nerve somatosensory evoked potential (SSEP) grades and Glasgow Coma Scale (GSC) scores were obtained from 51 patients with head injuries within 1 week after the injury to determine the relationship of these scores, both individually and combined, to outcome scores obtained more than 6 months after the injury. SSEP grading was based on the presence or absence of the cortical evoked potential, the amplitude of the early cortically generated P22 wave form, and the conduction time through the brain (P/N13-N20 interpeak latency). SSEP responses from both sides of the brain were combined and graded from 1 to 6. The GCS was graded without the verbal component (maximum score, 10), because all patients were intubated. All patients were unresponsive to commands. Median SSEP grades correlated better with Glasgow Outcome Scale and Barthel Index scores (R = 0.57 and 0.64, respectively; P &lt; 0.00001) than GCS scores did (R = 0.35 and 0.37, respectively, P &lt; 0.00001), and combining SSEP grades and GCS scores did not improve the predictive power of the model (R = 0.57 and 0.64, respectively; P &lt; 0.00001). All SSEP Grade 1 patients (n = 13) either died or remained in a vegetative state. In contrast, all SSEP Grade 6 patients (n = 7) had a moderate disability or good recovery. This study demonstrates the prognostic value of early quantitative median nerve SSEP grading for patients with head injuries who are unresponsive to commands within 1 week after the injury.
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Mambil, William Jerick L., Erwin Yancy A. Erbina, Gene Paula B. Pinuela, Ann Stefanie A. Pecson, and Jasmer Omaria M. Sugay. "The Relationship Of Elementary Pupils’ Final Test Score And Their Conduct Grades In School Of Saint Anthony, Quezon City." Proceedings Journal of Interdisciplinary Research 1 (November 22, 2014): 104–7. http://dx.doi.org/10.21016/irrc.2014.14ntt008.

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The purpose of this research is to determine the relationship between the Elementary pupils’ final test score in CL/GMRC and their conduct grades. This study was conducted to 941 Elementary pupils of the School of Saint Anthony with ages ranging from 6 to 13 years old. This research is quantitative in nature and used descriptive design. Frequency, percentage, means and Pearson r correlation served as the statistical tools of the study. The gathered means displayed that the elementary girls obtained higher scores in their final written exams and conduct grades than the boys. This is apparent across all grade school levels based on the computed means. The collected data present that most of the girls seemed to be more concerned with their grades and conscious of their school behavior compared to the boys. Weak positive relationships between the final written scores and conduct grades were determined based on the computed Pearson r in each grade level. Grade 1 obtained a person r of .176, grade 2 got an r of .294, grade 4 gained an r of .24, grade 5 obtained and r of .23 and grade 6 gained an r of .28. A moderate positive relationship, on the other hand, was calculated for the grade 3 level (.362). It can be derived from these findings that conduct grades in the Elementary levels may serve as a potential variable for the grade school pupils to achieve higher academic grades, particularly in the grade 3 level which is the transition level from lower school to middle school. Teachers, parents and other adults in the lives of the Elementary pupils play important roles in imbibing to the children the importance of being well-disciplined in class to attain higher scores during exams.
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Das, Prajna, Debahuti Mohapatra, Sushree Sumedha Dash, and Pranita Mohanty. "Immunohistochemical expression of epidermal growth factor receptor (EGFR) and p53 in Gliomas and correlation with clinicopathological parameters." Journal of medical pharmaceutical and allied sciences 11, no. 2 (March 30, 2022): 4645–49. http://dx.doi.org/10.55522/jmpas.v11i2.2503.

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The most common primary central nervous system (CNS) tumor originating from glial cells is Glioma. It accounts for approximately 80% of all primary malignant brain tumors. Our aim was to study the expressionof Epidermal Growth Factor Receptors (EGFR) and p53 by Immunohistochemistry (IHC) in Gliomas and to correlate with various histological types and grades as well as clinical parameters like age and gender of patients. It was an ambispective study for 1year and 2 months conducted in IMS Sum Hospital, Bhubaneswar. 38 cases of Gliomas operated in Neurosurgery Department were studied. Histological typing & grading were done according to WHO 2016 classification of CNS tumors. EGFR & p53 study was done by immunohistochemistry (IHC).Out of 38 cases, 14 cases (36.8%), 6 cases (15.7%), 6 cases (15.7%), 4 cases (10.5%), 6 cases (15.7%) and 2 cases (5.2%) were Astrocytoma, Oligodendroglioma, Glioblastoma, GBM with oligodendroglioma, Gliosarcoma and Ependymoma respectively. 2 cases (5.2%), 14 cases (36.8%), 6 cases (15.7%) and 16 cases (42.1%) were of Grade- I, II, III and IV respectively. In Grade I tumors, there was negative expression of both EGFR and p53. EGFR and p53 was positive in 57.14%, 71.42�ses of Grade II tumors respectively. Both the markers were 100% positive in Grade III and Grade IV tumors. Thus, there was positive and negative correlation with expression of both EGFR & p53 in higher grades low grades of tumors. Keywords: EGFR, Glioblastoma (GBM), p53, Immunohistochemical analysis, Clinical parameters.
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Веремеєнко, В. Ю. "Informative performance motor and functional training 6-7 grade girls." Teorìâ ta Metodika Fìzičnogo Vihovannâ, no. 4 (December 26, 2013): 32–39. http://dx.doi.org/10.17309/tmfv.2013.4.1034.

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Due to the significant deterioration of motor readiness piddlitkiv children and one of the main issues is the optimization of physical education physical education that requires informative indicators of control.The aim - to identify informative performance motor and functional training girls 6-7 grades.To solve the tasks we used the following methods: theoretical analysis and synthesis of scientific and methodological literature; teacher testing; methods of mathematical statistics.Results. Analysis of test results showed that the tests «to evaluate the perception of power parameters movements hands» (Test 6) and «long jump from place» (test 11) 7th grade girls show statistically significantly better than girls 6th class (p <0,05 ). And for the other results trend towards improved performance, but the difference in test results are not statistically significant.Conclusions. Informative indicator of motor readiness girls grades 6-7 are «Assessing the perception of power parameters movements hands» and «Jump into dovzhynu the place.»Ghencea test is the most informative and can be recommended to assess functional training class 6 girls. Serkina test may be recommended to evaluate the functional status of girls 7th grade.
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Levina-Yehorova, V. A. "Sexual features of the development of coordination abilities of children of middle school age (5-6 grades)." Health-saving technologies, rehabilitation and physical therapy 1, no. 1 (November 26, 2019): 153–58. http://dx.doi.org/10.58962/hstrpt.2019.1.1.153-158.

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The purpose of the study is to determine the dynamics of the sexual characteristics of the development of coordination abilities in students in grades 5-6. The study involved guys i girls of grade 5 (n = 11) and (n = 20), and students of the sixth grade: girls (n = 13) and boys (n = 17). An analysis of the test results shows that there are no statistically significant differences between boys of grades 5 and 6, except that boys in grades 6 show statistically significantly better results in tests for the manifestation of dynamic abilities. Girls are also the same - statistically significant differences are observed only in the test "jumping rope", which indicates the development of agility and coordination abilities with age.
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Rab, Jewell Ilias, Barna, Md Ashiqur Rahman Akanda, and Debabrata Paul. "Changes in Visual Acuity and Keratometry Readings following Pterygium Excision: A Study in A Public Medical College Hospital." Journal of National Institute of Ophthalmology 5, no. 2 (June 18, 2022): 25–30. http://dx.doi.org/10.3329/jnio.v5i2.66788.

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Introduction: Pterygium is a degenerative, triangular wing shaped, fibro vascular connective tissue of bulbar conjunctiva towards and onto the cornea, leading to significant astigmatism. It is a common ophthalmic condition of tropical and sub-tropical country like Bangladesh where there is dry sunny hot dusty climate. Purpose: To find out the change in visual acuity and keratomety before and after pterygium excision and effect of different grades of pterygium on the final outcome. Methods: This prospective study was carried out from March 2021 to December 2021 at Ophthalmolgy Department, Sher-E-Bangla Medical College & Hospital, Barishal. Total 68 patients with different grades of pterygium were operated for pterygium excision with conjunctival autograft and were studied and analyzed. All the eyes underwent detailed ocular examination like visual acuity measured by Snellen’s chart; refractive astigmatism measured by automated keratometry and slit lamp biomicroscopy and fundus examination. Results: Pterygium is more common in males (61.76%) than females (38.23%) where 45.59% cases were in age group of 31-40 years followed by 33.82% in 41-50 years and rare (2.94%) in more than 60 years; so, 86.76% cases are in the age group of 31-60 years. Preoperatively mean±SD of K1 (Horizontal meridian) was 42.428±1.853 D and 3 month after the surgery it was 42.061±0.563 D. On the other hand mean±SD of K2 (vertical) readings before surgical excision were 44.185± 0.871 D and postoperatively after 3 months it was 42.691±0.384 D. Pre and post-operative BCVA in Grade I pterygium cases were 6/6-6/9 both pre & post -operatively. In patients of Grade II preoperative VA was 6/18-6/36 which was postoperatively 6/12-6/18; in Grade III pre and postoperative VA was 6/24-6/36 and 6/12-6/18 respectively. While in Grade IV pterygium VA were 6/36-6/60 preoperatively and 6/18-6/24 postoperatively. Conclusion: We conclude that, the greater the grade of pterygium the lesser is the outcome of visual acuity after surgery; the greater was the change in keratometry reading. It was inferred that, timely and appropriate surgery at Grade II & Grade III can result in not only a good visual outcome but also less complications. J. Natl. Inst. Ophthalmol. 2022; 5(2):25-30
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Vazquez, M. F. "Invasive lobular carcinoma: to grade or not to grade." Yearbook of Pathology and Laboratory Medicine 2007 (January 2007): 37–39. http://dx.doi.org/10.1016/s1077-9108(08)70270-6.

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Pellett, Tracy L. "Children's Stereotypical Perceptions of Physical Activities: A K—12 Analysis." Perceptual and Motor Skills 79, no. 3 (December 1994): 1128–30. http://dx.doi.org/10.2466/pms.1994.79.3.1128.

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The purpose of this study was to examine grade (K—12) and gender differences for 638 children in stereotyping physical activities. Boys were more stereotypical in perceptions than girls. Children in Kindergarten, Grade 2, and Grade 8 were more stereotypical in perceptions than those in Grades 4, 6, 10, and 12.
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Saqib, Rukhtam, Siddhartha Wuppalapati, Hemant Sonwalkar, Karthikeyan Vanchilingam, Somenath Chatterjee, Gareth Roberts, and Nihal Gurusinghe. "Can further subdivision of the Raymond-Roy classification of intracranial aneurysms be useful in predicting recurrence and need for future retreatment following endovascular coiling?" Surgical Neurology International 13 (April 29, 2022): 170. http://dx.doi.org/10.25259/sni_991_2021.

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Background: The Raymond-Roy classification has been the standard for neck recurrences following endovascular coiling with three grades. Several modified classification systems with subdivisions have been reported in literature but it is unclear whether this adds value in predicting recurrence or retreatment. Our aim is to assess if these subdivisions aid in predicting recurrence and need for retreatment. Methods: A retrospective review of all patients undergoing endovascular coiling between 2013 and 2014. Patients requiring stent assistance or other embolization devices were excluded from the study. The neck residue was graded at time of coiling on the cerebral angiogram and subsequent 6, 24, and 60 months MRA. Correlation between grade at coiling and follow-up with need for subsequent retreatment was assessed. Results: Overall, 17/200 (8.5%) cases required retreatment within 5 years of initial coiling. 4/130 (3.1%) required retreatment within 5 years with initial Grade 0 at coiling, 6/24 cases (25%) of those Grade 2a, 4/20 cases (20%) Grade 2b, 3/8 (38%) Grade 3, and none of those with Grade 1. Large aneurysms ≥11 mm had an increased risk of aneurysm recurrence and retreatment. About 9.7% of ruptured aneurysms required retreatment versus 4.4% for unruptured. About 55% of carotid ophthalmic aneurysms were retreated. Conclusion: Although the modified classification system was significantly predictive of progressive recurrence and need for retreatment, no significant difference between the subdivisions of Grade 2 was observed. Similar predictive value was seen when using the Raymond-Roy classification compared to the new modified, limiting the usefulness of the new system in clinical practice.
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44

Sajjadi-Bafghi, Seyed Hossein. "Sex and Grade Differences in Verbal Creative Thinking among Iranian Middle-School Children." Psychological Reports 100, no. 3 (June 2007): 759–67. http://dx.doi.org/10.2466/pr0.100.3.759-767.

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The relations of sex and grade with verbal originality of 407 boys and 479 girls ( M age = 12.7 yr., SD=.9) in Iranian middle schools (Grades 6 through 8) were investigated. The Sounds and Images test, one of the components of Thinking Creatively with Sounds and Words, was administered to measure verbal originality. Analysis showed boys scored significantly higher than girls on verbal originality and Grade 6 children scored significantly higher than Grade 7 children. The results were discussed in terms of sociocultural factors.
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Teppo, Moonika, Regina Soobard, and Miia Rannikmäe. "A Study Comparing Intrinsic Motivation and Opinions on Learning Science (Grades 6) and Taking the International PISA Test (Grade 9)." Education Sciences 11, no. 1 (January 1, 2021): 14. http://dx.doi.org/10.3390/educsci11010014.

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Research findings indicate a decline in students’ motivation towards science learning through grade levels. However, there is a lack of studies investigating students’ motivation comparing learning between science subjects and at different school levels. Using self-determination theory as a framework, this study compares perceived changes in intrinsic motivation and student opinions on the relevance of learning science themes among students in grades 6 and 9 (the end of compulsory schooling). To explore such learning, a multidimensional validated instrument is developed and used to collect empirical data from 2673 grade 6 students and 848 grade 9 students. Results from this research indicate statistically significant subject differences regarding sub-components of intrinsic motivation and a declining trend in students’ opinions on the sub-scales of relevance for learning science themes with age. The results further indicate that grade 6 students report significantly higher science-related intrinsic motivation compared with grade 9 students. Suggestions and implications for practice and the potential impact on PISA science studies are discussed.
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Franklin, Bobby J., and Stephen B. Trouard. "Comparing dropout predictors for two state-level panels using Grade 6 and Grade 8 data." Journal of Educational Research 109, no. 6 (July 6, 2016): 631–39. http://dx.doi.org/10.1080/00220671.2015.1016601.

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47

Mardiyah, Mardiyah. "The Teachers' Efforts in Forming Social Competence of Sixth Grade Students of Elementary Schools in Sungai Ambawang." JP2D (Jurnal Penelitian Pendidikan Dasar) UNTAN 2, no. 2 (October 14, 2019): 63. http://dx.doi.org/10.26418/jp2d.v2i2.71.

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This study is titled Teachers' Efforts in Forming Social Competence of Grade 6 Students of 36 Primary Schools in Sungai Ambawang, Kubu Raya Regency. The problems studied are 1). How is the teacher's effort in shaping the social competence of grade 6 students of 36 Ambawang River elementary schools in schools? 2). How is the teacher's effort in shaping the social competence of grade 6 students of 36 Ambawang River elementary schools at home? 3). Are there any inhibiting factors in teacher efforts in shaping the competence of grade 6 students at 36 elementary schools in Sungai Ambawang? The method used is descriptive qualitative, using participant observation, interviews, and documentation of research instruments. The sample of this study was seven students, five people in sixth grade, and 2 in fifth class. The findings of this study explained that the efforts of teachers, students in grades 6 and 5 in the effort to establish social competence had been carried out well, but it hasn't been held maximally. Social Competence of students is medium and well-formed, but a small number of others still have problems in terms of time and willingness to enter challenging conditions in a particular social situation.
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48

Mei, Tao, Zhengjun Wang, Jianwu Wu, Xianhua Liu, Wei Tao, Shousen Wang, and Fuyong Chen. "Expression of GLUT3 and HIF-1α in Meningiomas of Various Grades Correlated with Peritumoral Brain Edema." BioMed Research International 2020 (August 30, 2020): 1–9. http://dx.doi.org/10.1155/2020/1682352.

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Aim. To investigate the expression of glucose transporter 3 (GLUT3) and hypoxia-inducible factor-1α protein (HIF-1α) in meningiomas and analyze the correlation between GLUT3 and HIF-1α expression with the pathological grade of peritumoral brain edema (PTBE) of meningiomas. Methods. In this cross-sectional study, we analyzed meningioma specimens from 160 patients collected from January 1, 2014, to December 1, 2017, by dividing them into a low-grade (WHO I) or high-grade (WHO II and WHO III) group. Immunohistochemical analyses were used to detect the expression level of GLUT3 and HIF-1α in the tumor specimens. Results. The proportion of GLUT3-positive staining in tumors sized <4 cm, 4–6 cm, and>6 cm was 35.9% (37/103), 63.6% (28/44), and 53.8% (7/13), respectively (P=0.007). The proportion of HIF-1α-positive staining in tumors sized <4 cm, 4–6 cm, and >6 cm was 41.7% (43/103), 68.2% (30/44), and 38.5% (5/13), respectively (P=0.010). The proportion of GLUT3-positive staining in the high-grade group and low-grade group was 70.8% (34/48) and 33.9% (38/112), respectively (P<0.001). The proportion of HIF-1α-positive staining in the high-grade group and low-grade group was 62.5% (30/48) and 42.9% (48/112), respectively (P=0.023). GLUT3-positive expression in meningioma PTBE grades 0, I, II, and III was 20.3% (13/64), 41.2% (14/34), 63.6% (21/33), and 82.8% (24/29), respectively (Bonferroni-corrected, P<0.001, α/6=0.008). HIF-1α-positive expression in meningioma PTBE grades 0, I, II, and III was 34.4% (22/64), 47.1% (16/34), 54.5% (18/33), and 75.9% (22/29), respectively (Bonferroni-corrected, P=0.003, α/6=0.008). Spearman’s correlation analysis revealed a correlation between the expression of GLUT3 and HIF-1α in meningiomas (r=0.463, P<0.001). Multivariate analysis revealed that GLUT3-positive expression, HIF-1α-positive expression, and high pathological grade were associated with the development of PTBE (P<0.05). Conclusions. GLUT3 and HIF-1α expression in meningiomas was closely related to the tumor size, pathological grade, and PTBE. This study is the first to report a unique map-like multifocal GLUT3 staining pattern in meningiomas.
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Fröhlich, András, Bernard Rice, and Gemma Vicente. "The Conversion of Low Grade Tallow into Biodiesel-Grade Methyl Ester." Journal of the American Oil Chemists' Society 87, no. 7 (March 17, 2010): 825–33. http://dx.doi.org/10.1007/s11746-010-1561-6.

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50

Smith, Theresa L. "Self-Concepts of Youth Sport Participants and Nonparticipants in Grades 3 and 6." Perceptual and Motor Skills 62, no. 3 (June 1986): 863–66. http://dx.doi.org/10.2466/pms.1986.62.3.863.

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Increasing concern has been expressed about the possible detrimental effects of competitive youth sports upon aspects of psychological development, especially concerning aggression, anxiety, and poor self-concept. This study examined the self-concepts of 208 participants and nonparticipants in third and sixth grade youth team spores from urban, middle, and lower middle-class backgrounds. A three-factor (participation × grade × sex) analysis of variance applied to self-concept data yielded a significant main effect with participants higher in self-concept than nonparticipants. Significant interactions indicated that differences were not uniform. Perhaps at different ages (grades) participation and nonparticipation in youth team sports may provide different social reinforcement for boys and girls.
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