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Journal articles on the topic 'Gradiente termico'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 April 2022

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1

Waite, J. H., E. Vaccaro, C. Sun, and J. M. Lucas. "Elastomeric gradients: a hedge against stress concentration in marine holdfasts?" Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 357, no. 1418 (2002): 143–53. http://dx.doi.org/10.1098/rstb.2001.1025.

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The byssal threads of marine mussels are elastomeric fibres with a great capacity for absorbing and dissipating energy. Up to 70% of the total absorbed energy can be dissipated in the byssus. Because byssal threads attach the mussel to hard inert surfaces in its habitat, they must combine the need to be good shock absorbers with appropriate matching of Young's modulus between living tissue and a hard sub–stratum such as stone—stiffnesses that can differ by five orders of magnitude. Recent data suggest that improved modulus matching and decreased stress concentration between different portions

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Moss, Christopher L., Thomas W. Chung, Václav Čeřovský, and František Tureček. "Electron transfer dissociation of a melectin peptide: correlating the precursor ion structure with peptide backbone dissociations." Collection of Czechoslovak Chemical Communications 76, no. 4 (2011): 295–309. http://dx.doi.org/10.1135/cccc2011025.

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Electron transfer dissociation (ETD) of doubly and triply charged ions from the amphipathic N-terminal decapeptide GFLSILKKVL-NH2 segment of melectin gave different distributions of fragment ions. The triply charged ions generated extensive series of fragment ions of c and z type that covered the entire sequence from both the N and C termini. In contrast, electron transfer to the doubly charged ions caused backbone cleavages that occurred at residues close to the N and C termini. Attachment of a free low-energy electron to the doubly charged ions caused primary dissociations close to the N and

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Chiu, Roger, and Duane P. Grandgenett. "Avian Retrovirus DNA Internal Attachment Site Requirements for Full-Site Integration In Vitro." Journal of Virology 74, no. 18 (2000): 8292–98. http://dx.doi.org/10.1128/jvi.74.18.8292-8298.2000.

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ABSTRACT Concerted integration of retrovirus DNA termini into the host chromosome in vivo requires specific interactions between thecis-acting attachment (att) sites at the viral termini and the viral integrase (IN) in trans. In this study, reconstruction experiments with purified avian myeloblastosis virus (AMV) IN and retrovirus-like donor substrates containing wild-type and mutant termini were performed to map the internalatt DNA sequence requirements for concerted integration, here termed full-site integration. The avian retrovirus mutations were modeled after internal att site mutations s

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4

Gondra, José, and Inára Garcia. "A arte de endurecer "miolos moles e cérebros brandos": a racionalidade médico-higiênica e a construção social da infância." Revista Brasileira de Educação, no. 26 (August 2004): 69–84. http://dx.doi.org/10.1590/s1413-24782004000200006.

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Pensar a infância implica trabalhar com a idéia de uma vida segmentada, construir marcos de começo e término das diferentes fases, num gradiente de idades evolutivo e linear. Assim, a tentativa de especificar essas etapas termina por repartir a vida de forma detalhada, além de unificar o que se encontra recoberto em cada uma das supostas idades da vida. Unificação que não é propriedade de um passado mais recuado, pois persiste na atualidade a crença em uma infância homogênea e cronologicamente repartida. Dessa forma, a cronologia da vida, problematizada nesse trabalho, considera tanto a base,

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Lacabana, Pablo. "Gradiente de vulnerabilidad socio-ambiental en el Partido de Quilmes, Provincia de Buenos Aires, Argentina." Revista Geográfica, no. 164 (January 31, 2022): 39–62. http://dx.doi.org/10.35424/regeo.164.2022.1041.

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El concepto de adaptación al cambio climático nos remite a posibles actuaciones emprendidas anticipadamente para reducir la vulnerabilidad de un sistema, de una ciudad o de un grupo social. Para generar capacidad adaptativa, es decir poder evitar pérdidas y acelerar la recuperación tras cualquier impacto climático, resulta fundamental, entre otras acciones, contar con información territorial. Detectar a tiempo las vulnerabilidades como fragmentaciones territoriales producidas por la desigualdad socio-ambiental, pueden hacer la diferencia para una eficiente gestión del riesgo. Es por ello, que

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Miranda-Rottmann, Soledad, Andrei S. Kozlov, and A. J. Hudspeth. "Highly Specific Alternative Splicing of Transcripts Encoding BK Channels in the Chicken's Cochlea Is a Minor Determinant of the Tonotopic Gradient." Molecular and Cellular Biology 30, no. 14 (2010): 3646–60. http://dx.doi.org/10.1128/mcb.00073-10.

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ABSTRACT The frequency sensitivity of auditory hair cells in the inner ear varies with their longitudinal position in the sensory epithelium. Among the factors that determine the differential cellular response to sound is the resonance of a hair cell's transmembrane electrical potential, whose frequency correlates with the kinetic properties of the high-conductance Ca2+-activated K+ (BK) channels encoded by a Slo (kcnma1) gene. It has been proposed that the inclusion of specific alternative axons in the Slo transcripts along the cochlea underlies the gradient of BK-channel kinetics. By analyzi

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Mondal, Samiran, Nasim A. Begum, Wenjun Hu, and Tasuku Honjo. "Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins." Proceedings of the National Academy of Sciences 113, no. 11 (2016): E1545—E1554. http://dx.doi.org/10.1073/pnas.1601678113.

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Activation-induced cytidine deaminase (AID) is essential for the somatic hypermutation (SHM) and class-switch recombination (CSR) of Ig genes. Although both the N and C termini of AID have unique functions in DNA cleavage and recombination, respectively, during SHM and CSR, their molecular mechanisms are poorly understood. Using a bimolecular fluorescence complementation (BiFC) assay combined with glycerol gradient fractionation, we revealed that the AID C terminus is required for a stable dimer formation. Furthermore, AID monomers and dimers form complexes with distinct heterogeneous nuclear

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Flores-Hernández, Domingo, Julia Ramos-Miranda, Luis Amado Ayala-Pérez, and Francisco Gómez Criollo. "Environmental variation vs co-occurrence of two fish families (Gerreidae and Ariidae) in Terminos Lagoon, Campeche, Mexico." JAINA Costas y Mares ante el Cambio Climático 3, no. 1 (2021): 5–22. http://dx.doi.org/10.26359/52462.0121.

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Terminos Lagoon is recognized as an ecosystem of great diversity and productivity in the southern Gulf of Mexico. It is also the site of various anthropogenic activities in the lagoon as well as in its surroundings. In addition, in recent years this lagoon has showed variations in temperature and salinity as a result of global warming and/or watershed management. This has generated variations in the structure and function of fish communities, among other taxonomic groups. IIn this work, we analyze the changes in abundance and distribution associated with modifications in the salinity of fish s

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Kiss, T., M. L. Bortolin, and W. Filipowicz. "Characterization of the intron-encoded U19 RNA, a new mammalian small nucleolar RNA that is not associated with fibrillarin." Molecular and Cellular Biology 16, no. 4 (1996): 1391–400. http://dx.doi.org/10.1128/mcb.16.4.1391.

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We have characterized a new member (U19) of a group of mammalian small nuclear RNAs that are not precipitable with antibodies against fibrillarin, a conserved nucleolar protein associated with most of the small nucleolar RNAs characterized to date. Human U19 RNA is 200 nucleotides long and possesses 5'-monophosphate and 3'-hydroxyl termini. It lacks functional boxes C and D, sequence motifs required for fibrillarin binding in many other snoRNAs. Human and mouse RNA are 86% homologous and can be folded into similar secondary structures, a finding supported by the results of nuclease probing of

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Lewis, Michael. "Vitruvius and Greek aqueducts." Papers of the British School at Rome 67 (November 1999): 145–72. http://dx.doi.org/10.1017/s0068246200004530.

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VITRUVIO E GLI ACQUEDOTTI GRECILa sezione di Vitruvio (VIII 5-6.9) sugli acquedotti ha causato molte difficoltà agli studiosi della materia che non riescono a riconciliarlo né con le pratiche conosciute nell'occidente romano, né con le teorie dell'idraulica moderna. In questo articolo si sostiene che, con l'eccezione dei passaggi sulle dimensioni dei tubi e sulla distribuzione urbana, le fonti di Vitruvio siano interamente greche. La sua descrizione dei chorobates deriva da Carpo di Antiochia, i suoi dati sul gradiente da Filone di Bisanzio, mentre le sue specifiche riguardanti le condutture d

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Kraus, Ina, Markus Eickmann, Simone Kiermayer, et al. "Open Reading Frame III of Borna Disease Virus Encodes a Nonglycosylated Matrix Protein." Journal of Virology 75, no. 24 (2001): 12098–104. http://dx.doi.org/10.1128/jvi.75.24.12098-12104.2001.

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ABSTRACT The open reading frame III of Borna disease virus (BDV) codes for a protein with a mass of 16 kDa, named p16 or BDV-M. p16 was described as an N-glycosylated protein in several previous publications and therefore was termed gp18, although the amino acid sequence of p16 does not contain any regular consensus sequence for N glycosylation. We examined glycosylation of p16 and studied its membrane topology using antisera raised against peptides, which comprise the N and the C termini. Neither an N- nor a C-terminal peptide is cleaved from p16 during maturation. Neither deglycosylation of

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Khedr, Ahmed. "Thermal-hydraulic Fortran program for steady-state calculations of plate-type fuel research reactors." Nuclear Technology and Radiation Protection 23, no. 1 (2008): 19–30. http://dx.doi.org/10.2298/ntrp0801019k.

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The safety assessment of research and power reactors is a continuous process covering their lifespan and requiring verified and validated codes. Power reactor codes all over the world are well established and qualified against real measuring data and qualified experimental facilities. These codes are usually sophisticated, require special skills and consume a lot of running time. On the other hand, most research reactor codes still require much more data for validation and qualification. It is, therefore, of benefit to any regulatory body to develop its own codes for the review and assessment

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Kaplan, H., G. Oda, H. Bietlot, P. Carey, M. Pozsgay, and P. Fast. "Selective isolation of free or blocked amino-terminal peptides from protein digests by high performance liquid chromatography: application to the crystal protein of Bacillus thuringiensis." Biochemistry and Cell Biology 64, no. 12 (1986): 1226–33. http://dx.doi.org/10.1139/o86-161.

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A method for the selective isolation of amino-terminal peptides from enzymatic digests of proteins using high performance liquid chromatography (HPLC) is described. The rationale behind this method is based on the condition that after citraconylation of the free amino groups of the protein, followed by enzymatic digestion and reaction with fluorodinitrobenzene only peptides derived from the amino terminus will not contain a dinitrophenyl (Dnp) group. After removal of citraconyl groups at acid pH, the peptide mixture was subjected to HPLC using an Altex Ultrasphere octadecylsilane column. The s

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14

Brugger, Keith A. "The non-synchronous response of Rabots Glaciär and Storglaciären, northern Sweden, to recent climate change: a comparative study." Annals of Glaciology 46 (2007): 275–82. http://dx.doi.org/10.3189/172756407782871369.

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AbstractRabots Glaciär and Storglaciären, two small valley glaciers in the Swedish Arctic, have not behaved synchronously in response to recent climate change. Both glaciers advanced late in the 19th century and then began to retreat in response to a ~1˚C warming that occurred around 1910. By the mid-1980s the terminus and volume of Storglaciären had essentially stabilized, so it may have completed its response to the earlier warming. In contrast, ongoing thinning and retreat of Rabots Glaciär are substantial and suggest its response time is considerably longer. A time-dependent numerical mode

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15

Chinn, Trevor J., Clive Heydenrych, and M. Jim Salinger. "Use of the ELA as a practical method of monitoring glacier response to climate in New Zealand’s Southern Alps." Journal of Glaciology 51, no. 172 (2005): 85–95. http://dx.doi.org/10.3189/172756505781829593.

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AbstractIn lieu of direct glacier surface mass-balance measurements, equilibrium-line altitudes (ELAs) have been measured over a 28 year period at 50 selected glaciers distributed along the glacierized length of New Zealand’s Southern Alps. Analysis of the data shows that ELAs are a useful measurement of glacier response to annual climate fluctuations, although there is much variability in the degree of response between glaciers in any given year. Comparisons of individual glacier annual ELA with the mean for all annual ELAs of the Southern Alps show a large variation of individual glacier res

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Pezzi, Luciano Ponzi, Ronald Buss de Souza, and Mário F. L. Quadro. "Uma Revisão dos Processos de Interação Oceano-Atmosfera em Regiões de Intenso Gradiente Termal do Oceano Atlântico Sul Baseada em Dados Observacionais." Revista Brasileira de Meteorologia 31, no. 4 (2016): 428–53. http://dx.doi.org/10.1590/0102-778631231420150032.

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Resumo De um modo geral, a interação do oceano com a atmosfera em regiões de intensa atividade da mesoescala oceânica (frentes oceanográficas, meandros e turbilhões de escalas espaciais típicas de cerca de 100-500 km e escalas temporais de cerca de 2-3 meses) apresenta uma correlação positiva entre a temperatura da superfície do mar (TSM) e variáveis meteorológicas tais como a estabilidade da Camada Limite Atmosférica Marinha (CLAM), a intensidade do vento e os fluxos de calor, de momentum e de gases entre o oceano e a atmosfera. Isto sugere que o oceano força a atmosfera nas escalas espaciais

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17

Teuton, Jeremy R., and Curtis R. Brandt. "Sialic Acid on Herpes Simplex Virus Type 1 Envelope Glycoproteins Is Required for Efficient Infection of Cells." Journal of Virology 81, no. 8 (2007): 3731–39. http://dx.doi.org/10.1128/jvi.02250-06.

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ABSTRACT Herpes simplex virus type 1 (HSV-1) envelope proteins are posttranslationally modified by the addition of sialic acids to the termini of the glycan side chains. Although gC, gD, and gH are sialylated, it is not known whether sialic acids on these envelope proteins are functionally important. Digestion of sucrose gradient purified virions for 4 h with neuraminidases that remove both α2,3 and α2,6 linked sialic acids reduced titers by 1,000-fold. Digestion with a α2,3-specific neuraminidase had no effect, suggesting that α2,6-linked sialic acids are required for infection. Lectins speci

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Barnakov, Alexander N., Ludmila A. Barnakova, and Gerald L. Hazelbauer. "Comparison In Vitro of a High- and a Low-Abundance Chemoreceptor of Escherichia coli: Similar Kinase Activation but Different Methyl-Accepting Activities." Journal of Bacteriology 180, no. 24 (1998): 6713–18. http://dx.doi.org/10.1128/jb.180.24.6713-6718.1998.

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ABSTRACT In Escherichia coli, high-abundance chemoreceptors are present in cellular amounts approximately 10-fold greater than low-abundance chemoreceptors. Cells containing only low-abundance receptors exhibit abnormally low tumble frequencies and do not migrate effectively in spatial gradients. These defects reflect an inherent activity difference between the two receptor classes. We used in vitro assays to investigate this difference. The low-abundance receptor Trg mediated an ∼100-fold activation of the kinase CheA, only twofold less than activation by the high-abundance receptor Tar. In c

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Attoui, Houssam, Fauziah Mohd Jaafar, Mourad Belhouchet, Philippe de Micco, Xavier de Lamballerie, and Corina P. D. Brussaard. "Micromonas pusilla reovirus: a new member of the family Reoviridae assigned to a novel proposed genus (Mimoreovirus)." Journal of General Virology 87, no. 5 (2006): 1375–83. http://dx.doi.org/10.1099/vir.0.81584-0.

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Micromonas pusilla reovirus (MpRV) is an 11-segmented, double-stranded RNA virus isolated from the marine protist Micromonas pusilla. Sequence analysis (including conserved termini and presence of core motifs of reovirus polymerase), morphology and physicochemical properties confirmed the status of MpRV as a member of the family Reoviridae. Electron microscopy showed that intact virus particles are unusually larger (90–95 nm) than the known size of particles of viruses belonging to the family Reoviridae. Particles that were purified on caesium chloride gradients had a mean size of 75 nm (a siz

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Studholme, Joshua, and Sergey Gulev. "Concurrent Changes to Hadley Circulation and the Meridional Distribution of Tropical Cyclones." Journal of Climate 31, no. 11 (2018): 4367–89. http://dx.doi.org/10.1175/jcli-d-17-0852.1.

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AbstractPoleward trends in seasonal-mean latitudes of tropical cyclones (TCs) have been identified in direct observations from 1980 to the present. Paleoclimate reconstructions also indicate poleward–equatorward migrations over centennial–millennial time scales. Hadley circulation (HC) is often both implicitly and explicitly invoked to provide dynamical linkages to these shifts, although no direct analysis of concurrent changes in the recent period has been presented. Here, the observational TC record (1981–2016) and ERA-Interim, JRA-55, and MERRA-2 are studied to examine potential relationshi

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Vlot, A. Corina, Lyda Neeleman, Huub J. M. Linthorst, and John F. Bol. "Role of the 3′-Untranslated Regions of Alfalfa Mosaic Virus RNAs in the Formation of a Transiently Expressed Replicase in Plants and in the Assembly of Virions." Journal of Virology 75, no. 14 (2001): 6440–49. http://dx.doi.org/10.1128/jvi.75.14.6440-6449.2001.

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ABSTRACT Alfalfa mosaic virus (AMV) RNAs 1 and 2 encode the replicase proteins P1 and P2, respectively, whereas RNA 3 encodes the movement protein and the coat protein (CP). When RNAs 1 and 2 were transiently expressed from a T-DNA vector (R12 construct) by agroinfiltration ofNicotiana benthamiana, the infiltrated leaves accumulated minus-strand RNAs 1 and 2 and relatively small amounts of plus-strand RNAs. In addition, RNA-dependent RNA polymerase (RdRp) activity could be detected in extracts of the infiltrated leaves. After transient expression of RNAs 1 and 2 with the 3′-untranslated region

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Mangus, David A., Nadia Amrani, and Allan Jacobson. "Pbp1p, a Factor Interacting withSaccharomyces cerevisiae Poly(A)-Binding Protein, Regulates Polyadenylation." Molecular and Cellular Biology 18, no. 12 (1998): 7383–96. http://dx.doi.org/10.1128/mcb.18.12.7383.

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ABSTRACT The poly(A) tail of an mRNA is believed to influence the initiation of translation, and the rate at which the poly(A) tail is removed is thought to determine how fast an mRNA is degraded. One key factor associated with this 3′-end structure is the poly(A)-binding protein (Pab1p) encoded by the PAB1 gene inSaccharomyces cerevisiae. In an effort to learn more about the functional role of this protein, we used a two-hybrid screen to determine the factor(s) with which it interacts. We identified five genes encoding factors that specifically interact with the carboxy terminus of Pab1p. Of

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Picardi, Angelo, Giovanni de Girolamo, Giovanni Santone, et al. "2. Le caratteristiche strutturali delle SR." Epidemiologia e psichiatria sociale. Monograph Supplement 13, S7 (2004): 7–21. http://dx.doi.org/10.1017/s182743310000006x.

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La prima parte di questa monografia prende in esame le variabili di tipo strutturale delle SR, ovvero le caratteristiche quanti- e qualitative sia delle SR che dello staff curante. L'importanza delle caratteristiche strutturali delle SR è duplice: da un lato si trattava di comprendere in che misura il cambiamento strutturale innescato e promosso dalla Legge 180 si fosse tradotto in una effettiva e coerente trasformazione del contesto assistenziale, e dall'altro quale fosse il gradiente di variabilità delle strutture sul territorio nazionale (peraltro già messo in luce, in termini generali, nel

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Mackenzie, Bryan, Hitomi Takanaga, Nadia Hubert, Andreas Rolfs, and Matthias A. Hediger. "Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1)." Biochemical Journal 403, no. 1 (2007): 59–69. http://dx.doi.org/10.1042/bj20061290.

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DMT1 (divalent metal-ion transporter 1) is a widely expressed metal-ion transporter that is vital for intestinal iron absorption and iron utilization by most cell types throughout the body, including erythroid precursors. Mutations in DMT1 cause severe microcytic anaemia in animal models. Four DMT1 isoforms that differ in their N- and C-termini arise from mRNA transcripts that vary both at their 5′-ends (starting in exon 1A or exon 1B) and at their 3′-ends giving rise to mRNAs containing (+) or lacking (−) the 3′-IRE (iron-responsive element) and resulting in altered C-terminal coding sequence

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25

Nüsslein-Volhard, Christiane. "Determination of the embryonic axes of Drosophila*." Development 113, Supplement_1 (1991): 1–10. http://dx.doi.org/10.1242/dev.113.supplement_1.1.

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The principles of embryonic pattern formation have been studied extensively in many systems using classical experimental approaches. In Drosophila, a powerful combination of genetics and transplantation experiments, as well as molecular biology, have helped to elucidate the mechanisms that operate during oogenesis and early embryogenesis to establish a set of positional cues required for axis determination in the early embryo. In systematic searches for maternal effect mutations a small number of about 30 genes have been identified that specifically affect the process of determination of the e

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Rohner, Christoph, David Small, Jan Beutel, Daniel Henke, Martin P. Lüthi, and Andreas Vieli. "Multisensor validation of tidewater glacier flow fields derived from synthetic aperture radar (SAR) intensity tracking." Cryosphere 13, no. 11 (2019): 2953–75. http://dx.doi.org/10.5194/tc-13-2953-2019.

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Abstract. Following the general warming trend in Greenland, an increase in calving rates, retreat and ice flow has been observed at ocean-terminating outlet glaciers. These changes contribute substantially to the current mass loss of the Greenland Ice Sheet. In order to constrain models of ice dynamics as well as estimates of mass change, detailed knowledge of geometry and ice flow is needed, in particular on the rapidly changing tongues of ocean-terminating outlet glaciers. In this study, we validate velocity estimates and spatial patterns close to the calving terminus of such an outlet deriv

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Yang, Haibin, Mark Quigley, and Tamarah King. "Surface slip distributions and geometric complexity of intraplate reverse-faulting earthquakes." GSA Bulletin 133, no. 9-10 (2021): 1909–29. http://dx.doi.org/10.1130/b35809.1.

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Abstract Earthquake ground surface ruptures provide insights into faulting mechanics and inform seismic hazard analyses. We analyze surface ruptures for 11 historical (1968–2018) moment magnitude (Mw) 4.7–6.6 reverse earthquakes in Australia using statistical techniques and compare their characteristics with magnetic, gravity, and stress trajectory data sets. Of the total combined (summative) length of all surface ruptures (∼148 km), 133 km (90%) to 145 km (98%) align with the geophysical structure in the host basement rocks. Surface rupture length (SRL), maximum displacement (MD), and probabi

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Zheng, X. Long, Julie (Jihui) Ai, Ning Li, and David (Dezhi) Shang. "Apical Sorting of Adamts13 in Madin-Darby Canine Kidney (MDCK) Cells Requires Cub Domains Via Its Interaction with Detergent-Insoluble Glycosphingolipid- and Cholesterol-Enriched Rafts." Blood 104, no. 11 (2004): 3660. http://dx.doi.org/10.1182/blood.v104.11.3660.3660.

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Abstract ADAMTS13, a member of a disintegrin and metalloprotease with thrombospondin type 1 repeats family, is mainly synthesized in the liver and secreted into the blood stream. It limits platelet aggregation in small arteries by cleaving the Tyr1605-Met1606 bond of von Willebrand factor (VWF). ADAMTS13 consists of a propeptide, a metalloprotease domain and a disintegrin domain, first thrombospondin type 1 repeat (TSP1), followed by a Cys-rich domain and a spacer domain. The carboxyl terminus of ADAMTS13 contains seven more TSP1 repeats and two CUB domains. The distal carboxyl terminal TSP1 r

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Norman, Armando Henrique. "Iniquidades Sociais no contexto da Atenção Primária à Saúde." Revista Brasileira de Medicina de Família e Comunidade 7, no. 25 (2012): 217–19. http://dx.doi.org/10.5712/rbmfc7(25)681.

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A edição no 25 da RBMFC traz temas interessantes para os profissionais da APS/ESF, a começar pela experiência em uma unidade de saúde da Espanha que implementou o programa Mentoring para a capacitação de profissionais médicos e enfermeiros na realização de pequenas cirurgias e/ou procedimentos. Esse artigo explora o potencial instalado nos serviços de saúde para multiplicação de conhecimentos e habilidades entre pares, visando atender a carteira de serviços e melhorar tanto a resolutividade do profissional (e consequente autoestima) como a satisfação dos usuários do sistema de saúde. Já na seç

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Chávez, René E., Linda Manzanilla, Nayeli Peralta, Andrés Tejero, Gerardo Cifuentes, and Luis Barba. "Estudio magnético y de resistividad en los alrededores de la Pirámide del Sol, Teotihuacán, México." Geofísica Internacional 33, no. 2 (1994): 243–55. http://dx.doi.org/10.22201/igeof.00167169p.1994.33.2.473.

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La existencia de cuevas y túneles en los alrededores de la ciudad prehispánica de Teotihuacán, México es muy conocida. El descubrimiento de un túnel que termina en una cámara tetralobulada debajo de la Pirámide del Sol condujo a pensar sobre la relación entre los ediï¬cios prehispánicos y esta clase de estructuras. El descubrimiento de un mayor número de cuevas y túneles en zonas aledañas a Teotihuacán, ej. Oztoyohualco, localizado a unos cuantos kilómetros al NW de la Pirámide del Sol y estudios regionales condujeron a pensar en la existencia de una red de túneles y cuevas bajo la gran ciuda

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Feghhi, Shirin, Alexander St. John, Jeff Harris, et al. "VWF Cleavage Products Inhibit Shear-Induced Self-Association." Blood 128, no. 22 (2016): 3718. http://dx.doi.org/10.1182/blood.v128.22.3718.3718.

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Abstract Background Von Willebrand factor (VWF) self-association is key to hemostasis in high-shear regions of the vasculature. Further, in pathologic small vessel thrombosis, VWF can also self-associate, even on an intact endothelium in the absence of vessel injury (Dong et al. Blood, 2002, 100:40339). VWF self-association preferentially occurs between large multimers, which are more sensitive to shear-induced unfolding. This process is regulated by ADAMTS13 proteolysis, which converts circulating ultra-large VWF multimers to smaller, less-adhesive multimers(Sadler. Proc Natl Acad Sci USA, 20

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Gemini, Laura, and Stefano Brilli. "Gradienti di liveness. Lo shaping socio-tecnico delle arti performative tra online e offline. Introduzione." Connessioni remote. Artivismo_Teatro_Tecnologia 3, no. 3 (2021). http://dx.doi.org/10.54103/connessioni/17286.

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Il presente articolo introduce il terzo numero della rivista dal titolo Gradienti di liveness. Lo shaping socio-tecnico delle arti performative tra online e offline. Dopo aver inquadrato il tema della liveness all’interno del processo di mediatizzazione del sociale e delle sfide alimentate dalla pandemia, viene discusso lo statuto del campo di studi sulla liveness. Si difende quindi e la necessità di uno sguardo che intende la liveness nei termini di “gradienti” con cui tale fenomeno si manifesta. Nella seconda parte vengono presentati i contenuti del numero, i quali mostrano le molteplici dir

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Lander, Rachel, and Christian P. Petersen. "Wnt, Ptk7, and FGFRL expression gradients control trunk positional identity in planarian regeneration." eLife 5 (April 13, 2016). http://dx.doi.org/10.7554/elife.12850.

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Mechanisms enabling positional identity re-establishment are likely critical for tissue regeneration. Planarians use Wnt/beta-catenin signaling to polarize the termini of their anteroposterior axis, but little is known about how regeneration signaling restores regionalization along body or organ axes. We identify three genes expressed constitutively in overlapping body-wide transcriptional gradients that control trunk-tail positional identity in regeneration. ptk7 encodes a trunk-expressed kinase-dead Wnt co-receptor, wntP-2 encodes a posterior-expressed Wnt ligand, and ndl-3 encodes an anteri

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Stewart, Gavin. "SLC14 family of facilitative urea transporters (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database." IUPHAR/BPS Guide to Pharmacology CITE 2019, no. 4 (2019). http://dx.doi.org/10.2218/gtopdb/f186/2019.4.

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As a product of protein catabolism, urea is moved around the body and through the kidneys for excretion. Although there is experimental evidence for concentrative urea transporters, these have not been defined at the molecular level. The SLC14 family are facilitative transporters, allowing urea movement down its concentration gradient. Multiple splice variants of these transporters have been identified; for UT-A transporters, in particular, there is evidence for cell-specific expression of these variants with functional impact [3]. Topographical modelling suggests that the majority of the vari

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Grinschpun, Luciano, Carlos Oldani, Matías Schneiter, Matías Valdemarin, and Juan Pereyra. "Obtención de compuesto de titanio con gradiente de porosidad mediante técnica pulvimetalúrgica." Matéria (Rio de Janeiro) 23, no. 2 (2018). http://dx.doi.org/10.1590/s1517-707620180002.0421.

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RESUMEN En el estudio de biomateriales de uso implantológico para la fabricación de distintos tipos de prótesis, el titanio es un metal que ha sido utilizado exitosamente debido a su buena resistencia a la corrosión y a su buena resistencia mecánica. A pesar de los avances realizados, en la actualidad aún subsisten algunos problemas con este material en aplicaciones de reemplazo óseo debido al alto valor de módulo elástico de este metal (110 GPa) en relación al del hueso cortical (20-30 GPa) y al hueso trabecular (1-5 GPa). Esta diferencia en los módulos elásticos del titanio y le hueso es una

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Zyserman, F. I., L. B. Monachesi, A. H. Thompson, T. D’Biassi, L. Jouniaux, and P. Gauzellino. "Numerical modeling of passive electroseismic surveying." Geophysical Journal International, March 30, 2022. http://dx.doi.org/10.1093/gji/ggac127.

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Summary This work reports numerical modeling of electroseismic conversions when the electric field source originates in the atmosphere. Layered structures of conductivity anomalies yield rotated electric fields at reservoir depths as large as source fields at the surface. Active-source electroseismic field tests imaged reservoirs 1800 meters deep. However, the required high-power, dipole sources mediate against these methods finding practical application in hydrocarbon exploration. We extend previous research by considering the potential for using environmental electric fields to create useful

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González-Solis, Alicia, Daniel Torruco, and Ángel D. Torruco-González. "Análisis comparativo de los moluscos en la reserva de la biosfera Los Petenes y lagunas costeras del sureste de México." Bulletin of Marine and Coastal Research 47, no. 1 (2018). http://dx.doi.org/10.25268/bimc.invemar.2018.47.1.736.

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The phylum Mollusca is widely distributed in all types of environments. The species it contains are important for their multiple uses as food (as part of several trophic chains), as vectors of other groups of organisms, for the extraction of substances, and as sentinels ofnatural and induced environmental changes. In this work, a comparative evaluation of the malacological biodiversity associated with different habitats in the Los Petenes Biosphere Reserve in Campeche and in eight coastal water bodies in southeastern Mexico was performed.To obtain data comparable to those that were used in a p

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Dynes, Joseph L., Andriy V. Yeromin, and Michael D. Cahalan. "Cell-wide mapping of Orai1 channel activity reveals functional heterogeneity in STIM1-Orai1 puncta." Journal of General Physiology 152, no. 9 (2020). http://dx.doi.org/10.1085/jgp.201812239.

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Upon Ca2+ store depletion, Orai1 channels cluster and open at endoplasmic reticulum–plasma membrane (ER–PM) junctions in signaling complexes called puncta. Little is known about whether and how Orai1 channel activity may vary between individual puncta. Previously, we developed and validated optical recording of Orai channel activity, using genetically encoded Ca2+ indicators fused to Orai1 or Orai3 N or C termini. We have now combined total internal reflection fluorescence microscopy with whole-cell recording to map functional properties of channels at individual puncta. After Ca2+ store deple

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KRÜGER, MAURÍCIO MARCHAND. "MONITORAMENTO DE ÁREAS CONTAMINADAS POR HIDROCARBONETOSEXEMPLO DE UMA ÁREA URBANA EM CURITIBA." Boletim Paranaense de Geociências 52 (June 30, 2003). http://dx.doi.org/10.5380/geo.v52i0.4215.

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Métodos geoelétricos como o caminhamento elétrico e a sondagem elétrica vertical, em conjunto com o método eletromagnético GPR (Ground Penetrating Radar) foram utilizados na investigação de uma área urbana em Curitiba, impactada por derrame de diesel e lançamentos de efluentes oleosos, oriundos de uma oficina de manutenção de locomotivas. A área de estudo encontra-se em terreno alagadiço, característico da planície de inundação do rio Iguaçu. Seu perfil geológico é constituído por uma camada de solo orgânico com 1,5 metros de espessura, seguida por uma camada de argila plástica (0,5 m) e de um

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Ruokolainen, Visa, Aušra Domanska, Mira Laajala, Maria Pelliccia, Sarah J. Butcher, and Varpu Marjomäki. "Extracellular Albumin and Endosomal Ions Prime Enterovirus Particles for Uncoating That Can Be Prevented by Fatty Acid Saturation." Journal of Virology 93, no. 17 (2019). http://dx.doi.org/10.1128/jvi.00599-19.

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ABSTRACTThere is limited information about the molecular triggers leading to the uncoating of enteroviruses under physiological conditions. Using real-time spectroscopy and sucrose gradients with radioactively labeled virus, we show at 37°C, the formation of albumin-triggered, metastable uncoating intermediate of echovirus 1 without receptor engagement. This conversion was blocked by saturating the albumin with fatty acids. High potassium but low sodium and calcium concentrations, mimicking the endosomal environment, also induced the formation of a metastable uncoating intermediate of echoviru

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