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Academic literature on the topic 'Grading knee OA'
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Journal articles on the topic "Grading knee OA"
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Phalswal, Uma, Vandna Pandey, Ashok Kumar, and Abhay Elhence. "Correlation of Ahlback grading and knee society score in patients with moderate to severe osteoarthritis of the knee." International Journal of Research in Orthopaedics 7, no. 3 (April 26, 2021): 606. http://dx.doi.org/10.18203/issn.2455-4510.intjresorthop20211617.
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<p class="abstract"><strong>Background:</strong> Knee osteoarthritis (OA) is a most common rheumatological disorder that causes functional limitation and disability. The most common problem in knee OA are joint pain and stiffness. It will lead to decreased quality of life and it have a serious economic burden on any country due to effect of disability and treatment.</p><p class="abstract"><strong>Methods:</strong> A correlational study was conducted to find out correlation between Ahlback grading and knee society score (KSS) on a sample of 100 moderate to severe knee OA patients and 142 OA knees. Data was collected at orthopedics OPD, for a period of 3 months by purposive sampling.</p><p class="abstract"><strong>Results:</strong> On evaluation, mean age of the participants was 60.19±1.01. Out of 100 patients, 42 patients had bilateral knee OA, therefore total 142 knees included in the analysis. More than half (51%) participants were overweight. Only 34% subjects had compliament to physiotherapy. Around 76% subjects taking analgesics and massage therapy to reduce knee pain. Maximum 82.4% subjects had a poor knee condition in KSS and mean score is 49.07±1.06. Ahlback grading in X-ray had negative correlation -0.610 with KSS. Hence it is evaluated, both the scales have approximately same result as it is analyzed that both scales are moderately correlated. There is significant association of age, occupation and physiotherapy with Ahlback grading followed with KSS significant associated with BMI, occupation and physiotherapy.</p><p class="abstract"><strong>Conclusions:</strong> The study concluded that there is a moderate correlation found between Ahlback X-ray grading and knee society scoring. X-ray and knee society scoring (clinical evaluation) both are essential for effective treatment of OA.</p>
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Oikonomidis, Stergios A., Yannis V. Simos, Ioannis K. Toliopoulos, Ioannis I. Verginadis, Alexandros S. Oikonomidis, Vasilios N. Ragos, Spyridon Ch Karkabounas, Angelos M. Evangelou, and Dimitrios Peschos. "OXIDATIVE STRESS INCIDENCE ON THE SEVERITY OF KNEE OSTEOARTHRITIS." Journal of Musculoskeletal Research 20, no. 02 (June 2017): 1750008. http://dx.doi.org/10.1142/s0218957717500087.
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The aim of the study was to examine the incidence of oxidative stress on the severity of knee osteoarthritis (OA). Data were obtained from a previous pilot controlled trial among patients, diagnosed with OA in one or both knees, that were randomly assigned into two different treatment groups and were either supplemented with ascorbic acid and Vitamin E daily per os or treated with meloxicam. The following markers were estimated: A. Clinical markers: functionality of the knee (WOMAC index), pain (using a pain visual analogue scale) and severity of OA (Kellgren–Lawrence grading scale) B. Laboratory markers: total antioxidant capacity (TAC) and malonyldialdehyde (MDA) levels in the synovial fluid. The TAC of the knees was moderately correlated with the severity of OA and the level of pain whilst MDA concentration was weekly correlated. An average change of 5[Formula: see text]mM of a-tocopherol in TAC (4.6–5.5[Formula: see text]mM of a-tocopherol) defines the shift among stages of OA and the level of pain experienced by the patients. Neither TAC nor MDA were correlated with the Kellgren–Lawrence grading scale. Alleviation of oxidative stress should be a key objective for the therapeutic interventions (pharmacological and nonpharmacological) in knee OA. Even small improvements in antioxidant capacity of the synovial fluid may contribute to the patient’s quality of life and to the deceleration of the disease progression.
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Naorem, Ajit Singh, Jugindro Singh Ningthoujam, K. Wangjam, and RK Rajesh. "Does Radiologic Grading Predict Severity of Osteo-arthritis Knee." Indian Journal of Physical Medicine and Rehabilitation 27, no. 3 (2016): 73–77. http://dx.doi.org/10.5005/ijopmr-27-3-73.
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Abstract Objective Evaluation of association between pain and functional limitation of osteo-arthritis knee with radiographic features. Methods Total of 123 knee OA patients diagnosed on the basis of American College of Rheumatology Classification (ACR) Criteria for knee OA, attended in Physical Medicine and Rehabilitation (PMR) OPD, JNIMS, were included. Pain and disability were measured using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and radiological grading by Kellgren-Lawrence (KL) grading from x-ray of weight bearing antero-posterior and lateral views. Correlation between WOMAC score and KL grading analysed. Results Sex distribution M:F=9:32, mean age 59.48 (+ 9.8), mean disease duration 4.79 (+ 0.41) months. Correlations of WOMAC pain and KL grading and WOMAC disability and KL grading were insignificant (p > 0.05). Conclusions There is discordance between radiographic findings and clinical features of OA knee and we should not plan treatment on the basis of radiologic grading rather on the functional status and symptoms.
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Li, Bei, Yi-Li Zhang, and Shou-Yi Yu. "Synovial Fluid Eotaxin-1 Levels May Reflect Disease Progression in Primary Knee Osteoarthritis Among Elderly Han Chinese: A Cross-Sectional Study." CARTILAGE 10, no. 4 (March 22, 2018): 408–16. http://dx.doi.org/10.1177/1947603518764280.
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Objective The CC chemokine family member eotaxin-1, also named chemokine C-C motif ligand 11 (CCL11), has been detected in knee osteoarthritis (OA) and could induce breakdown of cartilage matrix. This study was performed to investigate the plasma and synovial fluid eotaxin-1 levels with the disease progression in elderly Han Chinese with primary knee OA. Design A total of 143 elderly primary knee OA patients and 135 healthy controls were enrolled in the study. The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was performed to evaluate the clinical severity. The radiographic severity was assessed by Kellgren-Lawrence (K-L) grading. Plasma and synovial fluid (SF) eotaxin-1 levels were explored using enzyme-linked immunosorbent assay. The SF levels of matrix metalloproteinase–3 (MMP-3) and interleukin-6 (IL-6) were also examined. Results Elevated plasma eotaxin-1 levels were found in knee OA patients compared with healthy controls. Eotaxin-1 levels in SF of knee OA patients with K-L grade 4 were significantly elevated compared with those with K-L grades 2 and 3. Meanwhile, knee OA patients with K-L grade 3 had significantly increased SF levels of eotaxin-1 compared with those with K-L grade 2. Plasma eotaxin-1 levels in different K-L grading did not reach significant difference. Eotaxin-1 levels in SF of knee OA patients were significantly associated with disease severity evaluated by KL grading criteria. In addition, eotaxin-1 levels in SF were positively related to clinical severity illustrated by WOMAC as well as biochemical markers MMP-3 and IL-6. Conclusions Eotaxin-1 levels in SF instead of plasma, were independently and positively related to the disease severity in elderly knee OA patients. The inhibition of eotaxin-1 and its related signaling pathways may serve as a novel therapeutic approach for OA progression.
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Hariyanto, Hori, John Butar Butar, Gatot Susilo Lawrence, FX Budhianto Suhadi, and Andi Husni Tanra. "Association Between Plasma Beta-endorphin and WOMAC Score in Female Patients with Knee Osteoarthritis." Indonesian Biomedical Journal 4, no. 2 (August 1, 2012): 107. http://dx.doi.org/10.18585/inabj.v4i2.169.
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BACKGROUND: β-endorphin plays a role in the descending pain control in the central nervous system. Central sensitization may be involved in the generating and maintenance of osteoarthritis (OA) pain. However, the correlation between β-endorphin and pain severity in OA has shown conflicting results. The aim of this study was to investigate the association between plasma β-endorphin and the severity of the disease. METHODS: This study was an observational cross-sectional study carried out on 60 female subjects with knee OA who fulfilled the inclusion criteria. Plasma β-endorphin was measured by a commercial enzyme-linked immunosorbent assay (ELISA) kit. Osteoarthritis knees were classified by the Kellegren-Lawrence (KL) grading (1-4) criteria. The Western Ontario McMaster University Osteoarthritis (WOMAC) scoring method was used to assess self-reported physical function, pain and stiffness. RESULTS: The mean of the participants' ages was 58 years old, ranging from 42 to 83 years. Overall, more than 70% of the participants were overweight with a mean of body mass index (BMI) of 27.59. More than 54% of the participants were diagnosed of having KL grading 3 or 4. Plasma β-endorphin was correlated inversely with the WOMAC subscale of stiffness (r=-0.286, p=0.0311), but no correlation was noted with the WOMAC subscale of pain and physical activity. There was no significant difference of the mean of plasma β-endorphin among the KL gradings. CONCLUSIONS: Plasma β-endorphin is associated with better WOMAC total score and stiffness subscale, but not associated with KL grading of OA. KEYWORDS: knee osteoarthritis, female, β-endorphin, WOMAC, Kellgren-Lawrence
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Widhiyanto, Lukas, Andre Triadi Desnantyo, Lilik Djuari, and Maynura Kharismansha. "CORRELATION BETWEEN KNEE OSTEOARTHRITIS (OA) GRADE AND BODY MASS INDEX (BMI) IN OUTPATIENTS OF ORTHOPAEDIC AND TRAUMATOLOGY DEPARTMENT RSUD DR. SOETOMO." (JOINTS) Journal Orthopaedi and Traumatology Surabaya 6, no. 2 (December 9, 2019): 71. http://dx.doi.org/10.20473/joints.v6i2.2017.71-79.
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Osteoarthritis (OA) is the number eight disease causes Years of Disability in developing countries. OA worsen life quality, from movement limitation until inability to perform normal daily routines. Obesity is one of the risk factor of OA. The doubles increasing trend of obesity from 1980, might possibly causes the escalation of OA case. However, there is still no study that explains the correlation between OA grade, especially knee OA, with Body Mass Index (BMI). The purpose of this study was to determine whether there is correlation between knee osteoarthritis (OA) grade with Body Mass Index (BMI) in outpatients of Orthopaedic and Traumatology department RSUD Dr. Soetomo. This study was cross-sectional study with analitical observational design and survey was the method to determine whether there is correlation between knee OA grade and BMI. Height and weight measurement and also knee x-ray reading were performed to determine the BMI and knee OA grade. The BMI categories that were used were based on standard from Health Department of Republic of Indonesia, while the grading system that were used were based on Kellgren-Lawrence’s grading system. Populations in this study were taken from the outpatients of Orthopaedic and Traumatology Department RSUD Dr. Soetomo during August until November 2015. After statistic test using Spearman correlation test was done, the result was p=0,822. It can be concluded that there was no significant correlation between knee OA grade and BMI. Furthermore, knee OA grade was not affected by BMI only, but also other risk factors as well.
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Tiulpin, Aleksei, and Simo Saarakkala. "Automatic Grading of Individual Knee Osteoarthritis Features in Plain Radiographs Using Deep Convolutional Neural Networks." Diagnostics 10, no. 11 (November 10, 2020): 932. http://dx.doi.org/10.3390/diagnostics10110932.
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Knee osteoarthritis (OA) is the most common musculoskeletal disease in the world. In primary healthcare, knee OA is diagnosed using clinical examination and radiographic assessment. Osteoarthritis Research Society International (OARSI) atlas of OA radiographic features allows performing independent assessment of knee osteophytes, joint space narrowing and other knee features. This provides a fine-grained OA severity assessment of the knee, compared to the gold standard and most commonly used Kellgren–Lawrence (KL) composite score. In this study, we developed an automatic method to predict KL and OARSI grades from knee radiographs. Our method is based on Deep Learning and leverages an ensemble of residual networks with 50 layers. We used transfer learning from ImageNet with a fine-tuning on the Osteoarthritis Initiative (OAI) dataset. An independent testing of our model was performed on the Multicenter Osteoarthritis Study (MOST) dataset. Our method yielded Cohen’s kappa coefficients of 0.82 for KL-grade and 0.79, 0.84, 0.94, 0.83, 0.84 and 0.90 for femoral osteophytes, tibial osteophytes and joint space narrowing for lateral and medial compartments, respectively. Furthermore, our method yielded area under the ROC curve of 0.98 and average precision of 0.98 for detecting the presence of radiographic OA, which is better than the current state-of-the-art.
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Cubukcu, Duygu, Ayse Sarsan, and Hakan Alkan. "Relationships between Pain, Function and Radiographic Findings in Osteoarthritis of the Knee: A Cross-Sectional Study." Arthritis 2012 (November 19, 2012): 1–5. http://dx.doi.org/10.1155/2012/984060.
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Objectives. The aim of this study was to investigate the relationships between pain, disability, and radiographic findings in patients with knee osteoarthritis (OA). Patients and Methods. A total of 114 patients with knee OA who attended the physical medicine and rehabilitation outpatient clinic were included in this study. The diagnosis was based on the American College of Rheumatology (ACR) criteria for knee OA. Age, duration of disease, and body mass index (BMI) of the patients were recorded. Radiographic features on the two-sided knee radiography were assessed with the Kellgren-Lawrence scale. The severity of knee pain, stiffness, and disability were measured using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Results. The mean age of the patients was 56.98 (±8.28) years and the mean disease duration was 4.14 (±4.15) years. Kellgren-Lawrence grading scale and age or disease duration were positively and significantly associated, whereas none of the WOMAC subscores were found to be related with Kellgren-Lawrence grading scale (). On the other hand, WOMAC disability scores were significantly associated with WOMAC pain and WOMAC stiffness (). Conclusions. Knee pain, stiffness, and duration of disease may affect the level of disability in the patients with knee OA. Therefore treatment of knee OA could be planned according to the clinical features and functional status instead of radiological findings.
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Zhao, Zhe, Enqi Li, Qing Cao, Jie Sun, and Baotong Ma. "Endothelin-1 concentrations are correlated with the severity of knee osteoarthritis." Journal of Investigative Medicine 64, no. 4 (February 25, 2016): 872–74. http://dx.doi.org/10.1136/jim-2015-000030.
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Endothelin-1, a potent vasoconstrictor regulator, contributes to articular cartilage destruction. Therefore, we aim to assess the correlation of endothelin-1 concentrations with the development and severity of knee osteoarthritis (OA). This study included a population of 209 patients with knee OA. Kellgren-Lawrence (KL) grading was utilized to score the severity of OA. The case group had higher serum endothelin-1 concentrations than controls. Patients with knee OA with a relatively higher grade showed significantly elevated serum and synovial fluid (SF) endothelin-1 concentrations compared with those with lower KL grades. A significant correlation was found between serum and SF endothelin-1 concentrations and KL grades. Serum and SF endothelin-1 concentrations are correlated with the development and progression of knee OA.
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Moniruzzaman, Mohammad, Muhammad Alamgir Mandal, Md Ariful Islam, Md Ashraful Haque, Md Ahsan Ullah, Syed Mozaffar Ahmed, Md Habibur Rahman, Md Zakir Hossain, and Md Masudur Rahman. "A study on knee osteoarthritis in physical medicine and rehabilitation department, Rangpur Medical College." KYAMC Journal 8, no. 2 (February 19, 2018): 18–23. http://dx.doi.org/10.3329/kyamcj.v8i2.35698.
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Background: Physical Medicine & Rehabilitation (PMR) Department has also been trying to provide services with specialized outdoor (referred patient only) set up for twenty million people of Rangpur division.Objectives: Study is to know the demographic study, clinical grading, examination findings and radiological changes of Knee osteoarthritis.Materials & Methods: It was an observational study. This study was done on referred patients of Knee osteoarthritis in PMR specialized outdoor of RpMCH from 20th September, 2012 to 20th October; 2012. The objective of this study is to know the demographic study, clinical grading, examination findings and radiological changes of knee osteoarthritis (OA). Consecutive sampling technique was adopted and total 34 samples were taken.Results: Among 30 study population, 4 (13.3%) were male, 26 (86.7%) were female and male: female ratio was 0.15 (Table I). The mean age was 52.20±9.572 (standard deviation) and P value was 0.000. Regarding Occupation, 18 (60%) were housewife, 10 (33.3%) were sedentary worker and 2 (6.7%) were businessmen (P value 0.002) (Table IV). Among the study population, 18 (60.0%) had both knee joint OA, 8 (26.7%) had right knee joint OA and 4 (13.3%) had left knee OA. The mean duration of knee joint pain was 25.33 ± 37.570 (standard deviation) month (P value 0.001) (Table VII). Among the study population, 4 (13.3%) had diabetes mellitus, 6 (20.0%) had hypertension, 2 (6.7%) had hypertension with ischemic heart disease and 2 (6.7%) had diabetes mellitus with hypertension with bronchial asthma and 16 (53.3%) were normotensive and nondiabetic (Figure 1). According to clinical grading of knee OA, 2 (6.7%) were in grade-1a, 6 (20%) were in grade-1b, 2 (6.7%) were in grade-2a, 4 (13.3%) were in grade-2b, 8 (26.7%) were in grade-3b, 8 (26.7%) were in grade-4 (P value 0.180 ) (Figure 2).Conclusion: This study reveals that clinically more advanced OA patients actually carrying early radiological changes.KYAMC Journal Vol. 8, No.-2, Jan 2018, Page 18-23
Dissertations / Theses on the topic "Grading knee OA"
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Sen, Koktas Nigar. Phd thesis, METU, 2008. http://etd.lib.metu.edu.tr/upload/12609347/index.pdf.
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Gait analysis is the process of collecting and analyzing quantitative information about walking patterns of the people. Gait analysis enables the clinicians to differentiate gait deviations objectively. Diagnostic decision making from gait data only requires high level of medical expertise of neuromusculoskeletal system trained for the purpose. An automated system is expected to decrease this requirement by a &lsquotransformed knowledge&rsquo
of these experts. This study presents a clinical decision support system for the detecting and scoring of a knee disorder, namely, Osteoarthritis (OA). Data used for training and recognition is mainly obtained through Computerized Gait Analysis software. Sociodemographic and disease characteristics such as age, body mass index and pain level are also included in decision making. Subjects are allocated into four OA-severity categories, formed in accordance with the Kellgren-Lawrence scale: &ldquo
Normal&rdquo
, &ldquo
Mild&rdquo
, &ldquo
Moderate&rdquo
, and &ldquo
Severe&rdquo
. Different types of classifiers are combined to incorporate the different types of data and to make the best advantages of different classifiers for better accuracy. A decision tree is developed with Multilayer Perceptrons (MLP) at the leaves. This gives an opportunity to use neural networks to extract hidden (i.e., implicit) knowledge in gait measurements and use it back into the explicit form of the decision trees for reasoning. Individual feature selection is applied using the Mahalanobis Distance measure and most discriminatory features are used for each expert MLP. Significant knowledge about clinical recognition of the OA is derived by feature selection process. The final system is tested with test set and a success rate of about 80% is achieved on the average.