Academic literature on the topic 'Graft versus host disease – Treatment'

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Dissertations / Theses on the topic "Graft versus host disease – Treatment"

1

Kaiser, Tina Katarina [Verfasser]. "Treatment of acute Graft-versus-Host Disease using inorganic-organic hybrid nanoparticles / Tina Katarina Kaiser." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2019. http://d-nb.info/1222265001/34.

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2

Lopez, Rodriguez Yelica Virginia. "Immunosuppressive properties of Wharton's jelly derived mesenchymal stromal cells in the treatment of graft versus host disease in rat model." Diss., Kansas State University, 2013. http://hdl.handle.net/2097/16331.

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Doctor of Philosophy<br>Department of Anatomy and Physiology<br>Mark L. Weiss<br>Graft Versus Host Disease (GVHD) is the major complication following hematopoietic stem cell transplantation. GVHD is activated by immunocompetent T cells presented in the donor grafted tissue. Due to the increased use of bone marrow transplantation to treat diverse malignancies, the incidence of GVHD has shown a notable increase. Depending of the degree of immunological mismatch between donor and host, 50-70% of patients develop GVHD after allogeneic Bone Marrow Transplantation (BMT). Once GVHD develops, mortalit
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3

Papert, Susanne [Verfasser], Holger [Akademischer Betreuer] Budde, Holger [Gutachter] Reichardt, and Hubertus [Gutachter] Jarry. "New approaches to improve Extracorporeal Photopheresis for the treatment of Graft-versus-Host Disease / Susanne Papert. Betreuer: Holger Budde. Gutachter: Holger Reichardt ; Hubertus Jarry." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2016. http://d-nb.info/1102536156/34.

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4

Theiss-Sünnemann, Jennifer [Verfasser], Holger [Akademischer Betreuer] Reichardt, Steven [Akademischer Betreuer] Johnsen, and Tobias [Akademischer Betreuer] Pukrop. "Molecular and cellular mechanisms of glucocorticoids in the treatment of acute graft-versus-host disease / Jennifer Theiss-Sünnemann. Gutachter: Holger Reichardt ; Steven Johnsen ; Tobias Pukrop. Betreuer: Holger Reichardt." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2012. http://d-nb.info/1042305749/34.

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5

Tomlins, Paul John. "Ocular graft-versus-host disease." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8114/.

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Haemopoietic Stem Cell Transplant (HSCT) is used as a treatment for a number of conditions particularly leukaemias. Following conditioning and HSCT, there is a ‘resetting’ of the immune system, which reconstitutes over a number of months. Graft-versus-Host Disease (GvHD) is a life-threatening complication of HSCT that includes severe, sight-threatening dry eye disease. In GvHD transplanted immune cells mount an immune response against the host. This thesis investigated how the immune cells of the conjunctiva are affected by HSCT and how the ocular surface leukocytes reconstitute. A non-invasiv
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6

Loschi, Michael. "CD19SFv-CAR regulatory T-cell prevent acute graft versus host disease and improve chronic graft versus host disease." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCC265.

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La greffe de cellules souches hématopoïétiques est une option curative pour de nombreuses maladies hématologiques malignes et bénignes. Cependant, son effet bénéfique est contrebalancé par le développement de la maladie du greffon contre l'hôte (GVHD) aiguë et chronique. Les options thérapeutiques permettant de réduire l'incidence et la gravité de la GVH reposent principalement sur des médicaments pan-immunosuppresseurs qui exposent le destinataire à des infections opportunistes et à une rechute de la maladie d'origine. Les immunothérapies à base de cellules T régulatrices (Treg) se sont révél
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7

Cavet, James. "Risk factors for graft-versus-host-disease." Thesis, University of Newcastle Upon Tyne, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250123.

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8

Mertlitz, Sarah [Verfasser]. "Angiogenesis in Graft-versus-Host Disease / Sarah Mertlitz." Berlin : Freie Universität Berlin, 2020. http://d-nb.info/1217657312/34.

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9

Dignan, F. L. "Novel strategies for managing graft-versus-host disease." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1368222/.

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Graft-versus-host disease (GvHD) is a major barrier to the successful outcome of allogeneic haematopoietic stem cell transplantation. This thesis investigates four novel strategies for managing GvHD: the role of extracorporeal photopheresis (ECP), the use of economic data to allow for funding of new treatments, the impact of a new dedicated GvHD clinic and the writing of national guidelines. The main hypothesis is that fortnightly ECP would improve signs and symptoms of chronic GvHD. A single centre retrospective analysis of 82 patients showed that this ECP schedule was effective with 94% of p
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10

Nestel, Frederick P. (Frederick Peter). "Macrophage effector mechanisms mediating acute graft-versus-host disease." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=41302.

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The study presented in this thesis is an investigation of M$ phi$ effector mechanisms that mediate the pathogenesis of acute graft-versus-host disease (GVHD). Since the time that the GVH reaction was first described the mechanisms underlying the development of the disease have not been characterized. We have examined the state of M$ phi$ activation in nonirradiated B6AF1 mice injected with either 60 $ times$ 10$ sp6$ (acute GVHD) or 30 $ times$ 10$ sp6$ (nonlethal GVHD) parental B6 lymphoid cells. TNF-$ alpha$ and nitric oxide (NO) generation by M$ phi$ occurs following priming by IFN-$ gamma$
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