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1

Skovbjerg, Susann. "Inflammatory mediator response to Gram-positive and Gram-negative bacteria in vitro and in middle ear infections." Göteborg : Clinical Bacteriology Section, Dep. of Infectious Medicine, Sahlgrenska Academy , University of Gothenburg, 2010. http://hdl.handle.net/2077/21533.

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2

Finney, Simon Jonathan. "Leukocyte recruitment in vivo : diverse effects of gram positive and gram negative bacterial cell wall components." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413481.

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3

Molloy, Heather M. "A study of potential serum markers for a diagnosis of gram-positive and gram-negative bacterial sepsis." Thesis, Aston University, 2004. http://publications.aston.ac.uk/11012/.

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Sepsis continues to be a major cause of morbidity and mortality as it can readily lead tosevere sepsis, septic shock, multiple organ failure and death. The onset can be rapid and difficult to define clinically. Despite the numerous candidate markers proposed in the literature, to date a serum marker for sepsis has not been found. The aim of this study was to assay the serum of clinically diagnosed patients with eithera Gram-negative or Gram- positive bacterial sepsis for elevated levels of nine potentialmarkers of sepsis, using commercially produced enzyme linked immunosorbent assays(ELISA). T
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4

Pinchuk, Tommy. "Optimization of pre-processing variables for hyperspectral analysis of focal plane array Fourier transform infrared images." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=98769.

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A genetic algorithm was employed to select the optimal combination of preprocessing variables, including data pretreatment, data manipulation and feature extraction procedures, for eventual clustering of a data set consisting of hyperspectral images acquired by a focal plane array Fourier transform infrared (FPA-FTIR) spectrometer. The data set consisted of infrared images of bacterial films, and the classification task investigated was the discrimination between Gram-positive and Gram-negative bacteria. The genetic algorithm evaluated combinations of variables pertaining to bacterial film thi
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5

Belcher, Pamela Elizabeth. "Role of toll-like receptors in immune and cardiovascular responses to pattern associated molecular patterns of gram-positive and gram-negative bacteria." Thesis, Imperial College London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.479166.

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6

Chung, Whasun Oh. "Macrolide resistance and its linkage to tetracycline resistance /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/9279.

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7

Pereira, Marlene António. "Influência das estruturas bacterianas externas na inativação fotodinâmica por uma porfirina catiónica." Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/14124.

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Mestrado em Biologia Aplicada<br>The main targets of photodynamic inactivation (PDI) are the external bacterial structures, cytoplasmic membrane and cell wall. In this work it was evaluated how the external bacterial structures influence the PDI efficiency. To reach this objective 8 bacteria with distinct external structures were selected; 4 Gram-negative bacteria (Escherichia coli, with typical Gram-negative external structures; Aeromonas salmonicida, Aeromonas hydrophila both with an S-layer and Rhodopirellula sp., with a peptidoglycan-less proteinaceous cell wall and with cytoplasm compartm
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8

Islam, Mohammad Ariful [Verfasser]. "Porcine alveolar macrophage responses to Gram-positive and Gram-negative bacterial components in innate immunity / Mohammad Ariful Islam." Bonn : Universitäts- und Landesbibliothek Bonn, 2013. http://d-nb.info/104587860X/34.

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9

Winzar, Renee. "Synthesis of Modified Analogues of 3-deoxy-D-manno-octulosonic Acid (KDO) as Probes to Investigate the Donor Substrate Specificity of KDO Transferase." Thesis, Griffith University, 2012. http://hdl.handle.net/10072/367860.

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There have always been reported cases of bacteria able to resist antibiotic treatment. Through recent history, infections with bacteria capable of resisting at least one type of drug treatment have become more commonplace [1,2,3]. The dearth of novel-acting antibiotics, combined with the resourcefulness of pathogenic bacteria under selective pressure means that humans are now faced with strains of bacteria that have developed resistance to multiple drugs. Of the few novel acting antibiotics developed in the last 30 years, most are targeted only to Gram positive bacteria, and reports of bacteri
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10

Al-Humiany, Abdulrahman Abdullah. "A comparison of the responses to environmental stress of the gram-positive bacterium Staphylococcus xylosus and the gram-negative bacterium Halomonas halo." Thesis, University of Sheffield, 1999. http://etheses.whiterose.ac.uk/10228/.

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Abdulrahman Al-Humiany (1999) A Comparison of the Responses to Enviromental Stress of the Gram-Positive Bacterium Staphylococcus xylosus and the Gram-Negative Bacterium Halomonas Halo. PhD Thesis, Department of Molecular Biology and Biotechnology, University of Sheffield. Salt tolerance of the Gram-negative bacterium, Halomonas Halo, was compared with the salt tolerance of a newly isolated Gram-positive coccus Staphylococcus xylosus. Both organisms grew over a range of salinities from 0.1 - 3.0 M NaCI in both rich medium containing yeast extract and in minimal medium. In the absence of yeast e
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11

Backlund, Ingrid. "Evaluation of a selective media for the detection of gram-positive bacteria in leg ulcers and pressure wounds." Thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-254614.

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Hard-to-heal ulcers are resource intensive due to the fact that they are difficult to treat and especially vulnerable to bacterial invasion. The bacterial culture contaminating these wounds often consist of several different bacterial organisms that originate from endogenous sources. Necrotic material in ischemic ulcers provide nutrition which support bacterial reproduction, increasing the risk of infection. Determining causative pathogen in infected ulcers proves to be difficult when culturing swab samples, however Staphylococcus aureus and hemolytic streptococci generally act as primary path
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12

Guedes, Juliana Campos Diniz. "Caracterização química e atividade biológica de extratos etanólicos de Curcuma longa e Bixa orellana /." Araçatuba, 2019. http://hdl.handle.net/11449/182359.

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Orientador: Elisa Helena Giglio Ponsano<br>Resumo: O objetivo deste estudo foi investigar a composição química e as atividades antimicrobiana e antioxidante dos extratos etanólicos de Curcuma longa e Bixa orellana, na busca por substituintes aos aditivos sintéticos utilizados na indústria de alimentos. Pela espectrometria de massa (GC-MS) foram identificados bisdemetoxicurcumina, demetoxicurcumina e curcumina no extrato de C. longa e prunina e naringenina no extrato de B. orellana. C. longa apresentou atividade antimicrobiana frente a Clostridium sporogenes e Staphylococcus aureus, com concent
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13

Blanchet, Marine. "Nouveaux dérivés aminostéroïdiens à usage antimicrobien en médecine vétérinaire." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0062.

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Actuellement, le traitement des pathologies infectieuses chez les bovins et les animaux de compagnie est menacé par l’accroissement de l’antibiorésistance et des bactéries multirésistantes. Il est donc primordial pour les entreprises pharmaceutiques vétérinaires de développer de nouvelles gammes d’agents antibactériens spécifiques au domaine animale. Dans ce contexte, il a été montré que certains polyaminostérols naturels tels que la squalamine possèdent un fort potentiel antimicrobien. Ainsi, l’objectif de ce travail de thèse est de répondre à la problématique présentée par la société Virbac
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14

Desai, Devika J. "Characterisation of Biofilm-Forming Ability and Haemolytic Activity of Clinical Group B Streptococcus (GBS) Isolates From the Urinary Tract." Thesis, Griffith University, 2020. http://hdl.handle.net/10072/398419.

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Urinary tract infections (UTIs) are among the most common infections caused by both Gram-negative and Gram-positive bacteria, acquired in the community and hospitals. There are three main groups of UTIs: (i) lower UTIs that affect the urethra or the bladder, (ii) upper UTIs that affect the kidneys, or (iii) asymptomatic bacteriuria (ABU). Group B Streptococcus (GBS) is a Gram-positive bacteria known to cause a variety of infections in neonates, pregnant women, the elderly or immunocompromised individuals. GBS has been estimated to cause 1-2% of all single organism UTIs. GBS has been shown to
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15

I, D'Agostino. "Polyalkylguanidines: new weapons to tackle bacterial resistance." Doctoral thesis, Università di Siena, 2019. http://hdl.handle.net/11365/1070884.

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In this historical period known as the antibiotic crisis era, the ever faster rise of bacterial strains resistant to the clinically used antibiotics along with the scientific research silent gap in the antibacterial field is treating seriously to the worldwide public health. Hence, we urgently need to develop new antibacterials agents with an innovative mode of action, able to trick the mechanisms of the pathogen resistance. In this alarming frame, aware of the antibacterial properties of guanidine moieties, Prof. M. Botta and his research group have evaluated the biological activity of a lin
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16

Pryor, Donald Edward. "Synthesis and Bioactivity Studies of Nanoparticles Based on Simple Inorganic and Coordination Gallium Compounds as Cellular Delivering Vehicles of Ga(III) Ions for Potential Therapeutic Applications." Kent State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=kent1543554532063877.

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17

Chuk, Oleksii Andriiovych. "Study experience of bacterial transformation by pGREEN plasmid." Thesis, Національний авіаційний університет, 2021. https://er.nau.edu.ua/handle/NAU/50621.

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Das S., Dash H. R. Microbial Biotechnology – A laboratory Manual for Bacterial Systems. New Delhi: Springer India, 2015. P. 35-72. DOI 10.1007/978-81-322-2095-4_2<br>The acquisition of practical skills in the genetic transformation of microorganisms is an integral part of the training of biotechnology students. The most common study practice is the integration of the green fluorescent protein (GFP) gene from jellyfish and the gene of ampicillin resistance into bacterial cells. The aim of the work was to adapt the standard procedure of bacterial transformation for educational purposes at the D
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18

Erlandsson, Marcus. "Surveillance of Antibiotic Consumption and Antibiotic Resistance in Swedish Intensive Care Units." Doctoral thesis, Linköping : Univ, 2007. http://www.bibl.liu.se/liupubl/disp/disp2007/med1019s.pdf.

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19

Muheim, Claudio. "Antibiotic uptake in Gram-negative bacteria." Doctoral thesis, Stockholms universitet, Institutionen för biokemi och biofysik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-148541.

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The increasing emergence and spread of antibiotic-resistant bacteria is a serious threat to public health. Of particular concern are Gram-negative bacteria such as Escherichia coli, Acinetobacter baumannii, Klebsiella pneumoniae or Pseudomonas aeruginosa. Some of these strains are resistant to a large number of antibiotics and thus our treatment options are rapidly declining. In addition to the increasing number of antibiotic-resistant bacteria, a major problem is that many of the antibiotics at our disposal are ineffective against Gram-negative bacteria. This is partly due to the properties o
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20

Woo, Kei-sheng Gibson, and 吳基昇. "Molecular epidemiology of anaerobic gram-positive bacilli bacteremia and discovery of six novel anaerobic gram-positive bacilli." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B29762984.

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21

Campbell, Joan Iyabo Amiemenoghena. "β-lactamase genes of gram-negative bacteria". Thesis, University of Edinburgh, 1986. http://hdl.handle.net/1842/15646.

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Two β-lactamase gene sequences encoded by <i>Ps. aeruginosa</i> RMS 149 plasmid and <i>Rps. capsulata</i> sp 108 were investigated. The genes were located using DNA recombinant techniques and their nucleic acid sequences were determined using the Sanger dideoxy-sequencing technique. The amino acid sequences were identified and compared with other characterised β-lactamases. They are both class A enzymes (Ambler classification). The pseudomonad plasmid encoded enzyme is expressed constitutively, but its gene sequence has an attenuator sequence - reminiscent of inducible bacterial synthetic oper
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22

Delvillani, F. "POST-TRANSCRIPTIONAL REGULATION IN GRAM NEGATIVE BACTERIA." Doctoral thesis, Università degli Studi di Milano, 2013. http://hdl.handle.net/2434/220058.

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Post-transcriptional regulation plays a pivotal role in gene expression control as it ensures a fast response to environmental changes. This is particularly important in unicellular organisms that are exposed to environmental changes. During my PhD, I studied different aspects of this type of regulation in two Gram-negative bacteria: Escherichia coli and the opportunistic pathogen Pseudomonas aeruginosa. In E. coli I investigated the role of the ribosomal protein S1 in the interplay between translation and mRNA decay. In particular we showed that S1 not associated to 30S can sequester and prot
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23

Gally, David Lawrence. "Cell wall assembly in gram positive bacteria." Thesis, University of Newcastle Upon Tyne, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287465.

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24

Valappil, Sabeel Padinhara. "Production of polyhydroxyalkanoates by gram positive bacteria." Thesis, University of Westminster, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434414.

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25

Fusté, i. Domínguez Ester. "Epigenetics of Antimicrobial Resistance in Gram-Negative Bacteria." Doctoral thesis, Universitat de Barcelona, 2012. http://hdl.handle.net/10803/97096.

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Resistance to antimicrobials is a well-known phenomenon leading to difficulties in the treatment of infectious diseases. The genetic determinants of such resistance are in general well understood: plasmids, transposons, insertion sequences and integrons are the most frequently related genetic elements. The word epigenetics refers to changes in the phenotype or in the gene expression caused by mechanisms other than underlying DNA sequence. In some cases these changes can remain for generations. Serratia marcescens is an enterobacterium characterized by its natural (intrinsic) resistance to
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26

Chan, Anson Chi-Kit. "Iron transport in two pathogenic Gram-negative bacteria." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/32406.

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Campylobacter jejuni and Escherichia coli strain F11 are two Gram-negative pathogens with a versatile armament of iron uptake systems to cope with the fluctuating host nutrient environment. Our current understanding of Gram-negative iron uptake systems focuses heavily on a prototypical scheme involving a TonB-dependent outer membrane receptor and an ABC transporter, with little knowledge on systems that do not fall neatly into this paradigm. The primary focus of this thesis is the characterization of three such atypical iron uptake proteins from C. jejuni (ChaN and P19) and pathogenic E. coli
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27

Wallace, Jeremy Iain. "Hyperinducible β-lactamase expression in gram-negative bacteria." Thesis, University of Bristol, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295568.

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28

Ismael, Mariam Mohamed. "Bioremediation of hexavalent chromium using gram-negative bacteria." Thesis, Sheffield Hallam University, 2014. http://shura.shu.ac.uk/19859/.

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Hexavalent chromium (Cr (VI)), the most toxic form of chromium, is widely used in industrial processes. As a result substantial amounts of Cr (VI) contaminated wastes are produced. The use of microbial cells as bioremediation of heavy metals is a potential alternative to conventional chemical methods. In this work, laboratory- scale experiments were performed to investigate Cr (VI) removal using five environmental Gram-negative bacterial strains, three of which were nosocomial strains. The potential of live and autoclaved bacterial strains was investigated to mitigate Cr (VI) from its initial
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BERTINI, ALESSIA. "Plasmid-mediated antimicrobial resistance in Gram-negative bacteria." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2008. http://hdl.handle.net/2108/641.

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L’epidemiologia dei plasmidi di resistenza è il principale mezzo per descrivere la diffusione delle resistenze agli antimicrobici. L’identificazione di plasmidi correlati associati a specifici geni di resistenza può aiutare a tracciare la disseminazione di plasmidi epidemici, aprendo nuovi scenari epidemiologici sui meccanismi di diffusione delle resistenze agli antimicrobici. Questo aspetto è particolarmente evidente quando si considerano plasmidi che sono associati alla diffusione delle Beta Lattamasi a Spettro Esteso (ESBL) come gli enzimi CTX-M, SHV, TEM. Lo scopo di questa tesi è st
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ACOSTA, GUTIERREZ SILVIA. "Permeability in Gram-negative bacteria: A microscopic journey." Doctoral thesis, Università degli Studi di Cagliari, 2017. http://hdl.handle.net/11584/248736.

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Bacteria multi-drug resistance is a challenging problem of contemporary medicine and a new molecular framework for antibiotics is needed. General bacterial porins are recognized as the main pathway for polar antibiotics, but the permeability rules are still under debate. Recent works in literature pointed the electrostatics of the channel to be responsible for its filtering mechanism, and some theoretical investigations are already reported in the literature aimed at characterizing the electrostatics inside water-filled channels. Using Molecular dynamics simulations we revealed the electrosta
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31

Hayhurst, Emma. "Peptidoglycan structure and dynamics in gram positive bacteria." Thesis, University of Sheffield, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434615.

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32

Wang, Lihui. "Sensing of gram positive bacteria in drosophila immunity." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670165.

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33

Johansson, Per. "Genetics of tetrapyrrole synthesis in gram-positive bacteria." Lund : Lund University, 1999. http://catalog.hathitrust.org/api/volumes/oclc/68944808.html.

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34

Wheeler, Richard. "Peptidoglycan architecture and dynamics in Gram-positive bacteria." Thesis, University of Sheffield, 2012. http://etheses.whiterose.ac.uk/2741/.

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The major structural determinant of most bacterial cells is the peptidoglycan layer, a network (the sacculus) of glycan strands cross-linked by short peptide stems which encompasses the entire bacterium. However the architecture of peptidoglycan, which must accommodate both the structural requirements of the cell and the dynamic processes of growth and division, is poorly understood. Most architectural studies have addressed the peptidoglycan of rod-shaped bacteria. The architecture in Gram-positive cocci and ovococci is largely uncharacterised, In this study, atomic force microscopy (AFM) of
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35

Hughes, Roxana Bejarano. "Distribution of a Novel Gram Negative, Capsule-Forming Bacterium." Thesis, University of North Texas, 1997. https://digital.library.unt.edu/ark:/67531/metadc500729/.

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A novel Gram negative, capsule-forming bacterium was previously isolated in Dr. G. Roland Vela's laboratory. The distribution of this bacterium in soils from various locations was investigated. Soil samples from 188 locations around the world were examined. Isolates of the bacterium were obtained from 50 of these soils, with 48 of the isolates found in soils from the southwestern United States and northern Mexico. This suggests that this region is the natural habitat of the bacterium. The other two isolates were obtained from Madrid, Spain and Taipei, Taiwan. None were found in soils from Sou
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Radhi, Ohood Aqeed. "Xenophagy in response to Gram-positive Staphylococcus aureus and Gram-negative Salmonella enterica sv. Typhimurium." Thesis, University of Strathclyde, 2018. http://digitool.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=30530.

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Autophagy is an important process for cell survival in the human body, which plays a critical role in fighting infections. Some infections exploit the autophagic system and are often promoted by autophagy. Recent evidence has suggested that Staphylococcus aureus has specialised mechanisms to evade xenophagy, thus allowing bacterial survival and replication within autophagosomes, leading to eventual cell death. ULK1 is a serine/threonine kinase that plays an essential role during the early steps of autophagosome biogenesis, but its roles during xenophagy following Staphylococcus aureus infectio
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37

Abdullah, Abdallah Ibansharred. "Virulence determinants of aeromonads and other gram-negative bacteria." Thesis, University of Liverpool, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275038.

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38

Ren, Chuan-Peng. "Comparative Genomics of Selected Species of Gram-Negative Bacteria." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/489/.

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Investigation of genomic diversity can provide insight into the evolutionary history of bacterial species. However, complete genome sequencing is not yet practical for large strain collections at the beginning of this project. In this project PCR-based methods to investigate the genomic diversity of non-sequenced strains were successfully developed. In \(Escherichia\) \(coli\), the distribution of two Type III secretion system, ETT2 (\(E.\) \(coli\) Type Three Secretion 2) and Flag-2 (\(E.\) \(coli\) Flagellar system 2), were surveyed among a collection of 79 strains. Remnants of both clusters
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39

Reid, Alison Jean. "Resistance to beta-lactam antibiotics in gram-negative bacteria." Thesis, University of Edinburgh, 1987. http://hdl.handle.net/1842/19258.

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40

George, Thompson Alayna Michelle. "Molecular Mechanisms of Copper Homeostasis in Gram-negative Bacteria." Diss., The University of Arizona, 2014. http://hdl.handle.net/10150/320968.

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Copper is a trace element utilized by organisms as a cofactor involved in redox chemistry, electron transport, photosynthesis, and oxidation reactions. In excess, copper is toxic; it can generate reactive oxygen species causing cellular damage, or poison other metalloproteins by replacing native metal cofactors. Gram-negative bacteria have developed homeostatic mechanisms to maintain the intracellular copper concentration in the face of changing environmental conditions. For Gram-negative enteric bacteria, like Esherichiacoli and Salmonella enterica serovar typhimurium, copper is encountered i
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Hreggvidsson, Gudmundur Oli. "Cytochromes c and the evolution of Gram positive bacteria." Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/14116.

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The content and cellular location of cytochromes in <I>Bacillus azotoformans</I> was examined under aerobic and denitrifying anaerobic conditions. An abundance of cytochromes was expressed. Two cytochromes were induced under aerobic conditions, one of which was only expressed under conditions of high aeration. One cytochrome, a b-type cytochrome, may be induced under denitrifying conditions. Cytochromes common to both pathways appear to be expressed in similar amounts per unit cell weight. Both c- and b-type cytochromes from <I>B. azotoformans</I> appear to be membrane bound, as they were only
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Nandivada, Lakshmi Sarada. "Beta-lactam resistance in gram-negative bacteria isolated in India." Thesis, University of Edinburgh, 1990. http://hdl.handle.net/1842/27101.

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The most important resistance mechanism to beta-lactam antibiotics is the plasmid-mediated beta-lactamase and the common criterion for the epidemiology of these enzymes is the determination of their biochemical characteristics. Surveys of plasmid-encoded beta-lactamases of Gram-negative bacteria, used to investigate their relative clinical importance, have been poorly performed and rarely conducted outside the developed world. A survey of uropathogenic strains and of salmonellae and shigellae, isolated in south India in 1984, revealed a higher incidence of ampicillin resistance (minimum inhibi
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Mak, Jennifer Ka Yan Biotechnology &amp Biomolecular Sciences Faculty of Science UNSW. "Integrons, resistance genes and their dissemination (in Gram- Negative Bacteria)." Awarded By:University of New South Wales. Biotechnology & Biomolecular Sciences, 2009. http://handle.unsw.edu.au/1959.4/44381.

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Antibiotic resistance is increasing worldwide, which is threatening the effectiveness of even the most potent and recent antibiotics. The successful treatment of disease is hampered due to the multidrug resistant (MDR) phenotype exhibited by the bacterial pathogens. Therefore, the aims of this thesis were to investigate MDR through several different approaches. Integrons are important contributors to the MDR profile of nosocomial isolates within Australia, therefore the incidence of integrons was assessed in a collection of 72 conjugative clinical plasmids isolated from E. coli, a cohort of
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44

Donald, James William. "The assembly of outer membrane proteins in gram-negative bacteria." Thesis, University of East Anglia, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492961.

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45

Kömerik, Nurgül. "Susceptibility of mucositis-associated Gram-negative bacteria to photodynamic action." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401728.

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46

Zheng, Tengfei. "Cargo delivery into gram-negative bacteria via enterobactin uptake machinery." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/91118.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemistry, 2014.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Chapter 1. Introduction to Iron Homeostasis and Siderophores Iron is an essential nutrient for almost all living organisms. This Chapter presents an overview of iron homeostasis in human and bacteria, as well as the biology and chemistry of siderophores and siderophore conjugates. Siderophores are small-molecule iron chelators synthesized by bacteria for scavenging iron from the environment. Their iron-binding properties, stru
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47

Hjelm, Anna. "Optimizing membrane and secretory protein production in Gram-negative bacteria." Doctoral thesis, Stockholms universitet, Institutionen för biokemi och biofysik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-123418.

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Proteins fulfil a wide variety of essential functions in the cell. Recombinant protein production in the Gram-negative bacterium Escherichia coli (E. coli) facilitates structural and functional studies of proteins and it has been instrumental in biotechnology for the manufacturing of e.g. many protein-based drugs. However, to obtain sufficient amounts of active recombinant protein is not always a trivial task. The production of proteins that reside in membranes is limited by their complex biogenesis and their hydrophobic nature. Consequently, despite the importance of membrane proteins in heal
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48

Wilcox, Ashley M. "Silver Nanoparticles: An effective antibacterial agent against Gram-negative bacteria." Wright State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=wright1576621225597745.

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49

Govindji, Nishal. "Inhibiting and characterising biofilms formed by gram-negative uropathogenic bacteria." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/inhibiting-and-characterising-biofilms-formed-by-gramnegative-uropathogenic-bacteria(b1dab3aa-ca56-4b0d-87e5-9c4c5bf11721).html.

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Urinary catheters are indispensable in healthcare and, with an ageing population, their use will continue to increase. However, they are commonly associated with colonisation and urinary tract infections (UTIs) caused by the attachment of bacteria to the catheter surface. Application of a novel cationic compound as a catheter coating may have a significant impact on the costs associated with treatment of UTIs and reduce the need for catheter replacement, as well as decreasing the number of UTI associated morbidity and mortality. Cationic compounds in particular are known to interact with the n
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Lee, Wan-Jing. "Isolation and characterisation of phages infecting gram positive food bacteria." Thesis, University of Canterbury. School of Biological Sciences, 2008. http://hdl.handle.net/10092/3429.

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Abstract:
Bacteriophage (phage), virus of bacteria, has been proposed as a mean to inactivate bacteria that are pathogens of humans. Applied prophylatically to food, phage might decrease the numbers of potential pathogens we ingest. Much active research on using the phages of bacteria to control Gram negative foodborne pathogens are described in the literatures, but comparatively little research describes the phages of Gram positive bacteria and their use as biocontrol agents on food. In this work, previous undescribed phages, able to infect Bacillus cereus and Listeria monocytogenes, were isolated from
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