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1

MARENCO, STEFANO, and DANIEL R. WEINBERGER. "The neurodevelopmental hypothesis of schizophrenia: Following a trail of evidence from cradle to grave." Development and Psychopathology 12, no. 3 (2000): 501–27. http://dx.doi.org/10.1017/s0954579400003138.

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This is a critical review of the literature related to the neurodevelopmental hypothesis of schizophrenia which posits that the illness is related to abnormal brain development. The review focuses on data deriving from clinical studies, and it is organized according to the life phase from which the data were collected: conception and birth, infancy and childhood up to the onset of the illness, after illness onset, and postmortem. The neurodevelopmental hypothesis is supported by several pieces of evidence, including increased frequency of obstetric complications in patients with schizophrenia;
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Tassadaq, Ali, Motsim Shah, Nadeem Akhtar, Munema Khan, Soban Gondal, and Mohsin Rana. "A Rare Presentation of Triplegia Resulting from Penetrating Brain Trauma by a Hand-Held Dagger." Pakistan Journal Of Neurological Surgery 27, no. 3 (2023): 172–76. http://dx.doi.org/10.36552/pjns.v27i3.841.

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Penetrating brain trauma is a devastating injury mode mostly seen in military settings. Its low-velocity counterpart resulting from objects such as knives, drills, daggers, etc. is relatively less common & rarely seen present mostly in isolated case reports. The neuropathological outcome can be disproportionately morbid in these cases with a varied clinical spectrum ranging from occult deficits to grave debilities reported. It is an anatomical insult whose course is free of clinical constraints & determined by the trajectory & velocity of the object. In this case report, an 18-year
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Jayaweera, Danushi Ashani, Anuja Abayadeera, and Vihara Dassanayake. "A ‘can’t intubate, can’t oxygenate’ situation during an elective redo thyroid surgery; successful rescue and the lessons learnt." Anaesthesia, Pain & Intensive Care 26, no. 5 (2022): 727–29. http://dx.doi.org/10.35975/apic.v26i5.1984.

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Pre-operative assessment of a patient for routine redo thyroidectomy requires a detailed airway assessment, clear documentation and formulation of an appropriate airway management plan by the anesthetist. Failure to identify problems related to oxygenation and ventilation during surgery will cause grave consequences to the patient and an unpleasant experience to the anesthetist and the surgeon. Redo thyroid surgery can be challenging. There is a possibility of preoperative vocal cord palsy due to previous surgical insult and infiltration by tumour recurrence, that can lead to difficulty in ven
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Sarkar, Swaimanti, Aindrila Chattopadhyay, and Debasish Bandyopadhyay. "Melatonin, the advance-guard in oxidative myocardial assault instigated by exercise stress: a physiological and biochemical insight." Melatonin Research 3, no. 4 (2020): 451–75. http://dx.doi.org/10.32794/mr11250072.

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Exercise conducted at an optimum training load is usually beneficial for the overall health of an individual. However, an unaccustomed intense exercise carried out by untrained individuals or elite athletes during over-training and/or competition-related stress often bear inevitable cardiovascular risks. Although many alterations occurring in the cardiovascular system during exercise are the results of training adaptations, sudden cardiovascular deaths reported in competitive athletes is a matter of grave concern. Several oxidative biomarkers that depict the underlying structural and functiona
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Khanal, Babita, Prakash Kafle, Sandip K. Singh, et al. "Early Outcome of Surgery in Pediatric Head Injury: Experience From a Tertiary Care Center in Eastern Nepal." Journal of Institute of Medicine Nepal 42, no. 2 (2020): 16–20. http://dx.doi.org/10.3126/jiom.v42i2.37529.

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Introduction Head injuries among the pediatric age group remain an unwelcomed source of morbidity and mortality resulting from falls, motor vehicle accidents, assaults, and child abuse. Early identification and management of traumatic brain injury (TBI) are crucial in halting the progress of the primary insult and preventing or reducing secondary brain injury. The present study aims to investigate the major cause of pediatric TBI and analyze the early outcome and serve as a reference study from a tertiary care center in eastern Nepal.
 MethodsThis is a prospective cohort study conducted i
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Khanal, Babita, Prakash Kafle, Sandip K. Singh, et al. "Early Outcome of Surgery in Pediatric Head Injury: Experience From a Tertiary Care Center in Eastern Nepal." Journal of Institute of Medicine Nepal 42, no. 2 (2020): 16–20. http://dx.doi.org/10.59779/jiomnepal.1104.

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Introduction: Head injuries among the pediatric age group remain an unwelcomed source of morbidity and mortality resulting from falls, motor vehicle accidents, assaults, and child abuse. Early identification and management of traumatic brain injury (TBI) are crucial in halting the progress of the primary insult and preventing or reducing secondary brain injury. The present study aims to investigate the major cause of pediatric TBI and analyze the early outcome and serve as a reference study from a tertiary care center in eastern Nepal. Methods: This is a prospective cohort study conducted in t
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Kanuri, Sri Harsha, Newly Bagang, Ayse Sena Ulucay, Popular Pandey, and Gaaminpreet Singh. "Innate defenses to intestinal cell death in necrotizing enterocolitis – spotlight on macrophage efferocytosis and its efficacy in rescuing inflamed intestinal mucosa." European Journal of Clinical and Experimental Medicine 21, no. 2 (2023): 365–96. http://dx.doi.org/10.15584/ejcem.2023.2.20.

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Introduction and aim. Necrotizing enterocolitis (NEC) is a grave gastrointestinal disease of preterm infants which is widely prevalent in the neonatal intensive care units. Current treatment options are very limited with high mortality and morbidity. With no disease specific interventions, understanding nascent cellular events that occur immediately after microbial insult can offer insights for devising novel treatment options for curtailing the disease progression in NEC. In this regard, intestinal cell death in NEC is a primordial cell-signaling event and is regarded as a harbinger of future
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Isnawan, Fuadi. "Protection of the Dignity of the Corpse: A Study on the Criminalization of Necrophilia Reviewed from the Maqashid Syariah." KRTHA BHAYANGKARA 18, no. 3 (2024): 496–526. https://doi.org/10.31599/krtha.v18i3.2682.

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Necrophilia in Indonesia has not been specifically regulated in the law. This causes a legal vacuum to punish the perpetrators of necrophilia in Indonesia. this research focuses on examining maqashid sharia in the criminalization of necrophilia in Indonesia. The research method used is normative research method. the results show that in Islamic teachings, necrophilia is considered a serious violation of the honor of the corpse which is highly respected, equivalent to respect for the living. This act not only violates the honor of the corpse but also the principle of keeping private parts and s
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Anetor, John Ibhagbemien, Chukwuemelie Zedech Uche, and Gloria Oiyahumen Anetor. "In pursuit of incorporation of markers of oxidative stress in traditional biochemical panels in clinical Chemistry: A risk assessment step in diagnosis and biotherapy." American Journal of Biopharmacy and Pharmaceutical Sciences 2 (January 6, 2022): 1. http://dx.doi.org/10.25259/ajbps_9_2021.

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Chemical pathology (clinical chemistry/biochemistry) is the branch of laboratory medicine concerned with the detection of alterations in the chemical constituents and biochemical mechanisms, which ensure health, culminating in disease. The disease itself is a pattern of response to some insult or injury resulting in a disturbed function or structure. It is often difficult to ascertain precisely the point of transition from health to a disease state. Pathological changes, including metabolic and molecular perturbations, with the potential to progress to clinical disease, are also present in hea
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Andrews, Peter J. D., Derek H. Sleeman, Patrick F. X. Statham, et al. "Predicting recovery in patients suffering from traumatic brain injury by using admission variables and physiological data: a comparison between decision tree analysis and logistic regression." Journal of Neurosurgery 97, no. 2 (2002): 326–36. http://dx.doi.org/10.3171/jns.2002.97.2.0326.

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Object. Decision tree analysis highlights patient subgroups and critical values in variables assessed. Importantly, the results are visually informative and often present clear clinical interpretation about risk factors faced by patients in these subgroups. The aim of this prospective study was to compare results of logistic regression with those of decision tree analysis of an observational, head-injury data set, including a wide range of secondary insults and 12-month outcomes. Methods. One hundred twenty-four adult head-injured patients were studied during their stay in an intensive care un
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Falvo, David J., Adrien Grimont, Paul Zumbo, et al. "Abstract PR008: An epigenetic memory of inflammation controls context-dependent lineage plasticity and KRAS-driven tumorigenesis in the pancreas." Cancer Research 82, no. 23_Supplement_2 (2022): PR008. http://dx.doi.org/10.1158/1538-7445.cancepi22-pr008.

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Abstract Tissue homeostasis depends on responses to environmental insults to restore cellular phenotype, microenvironment composition, and tissue architecture. Inflammation is essential to the disruption of homeostasis, and, in the pancreas, can destabilize the identity of terminally differentiated acinar cells. Herein we employ lineage-traced mouse models to delineate the chromatin dynamics that accompany the cycle of metaplasia and regeneration following pancreatitis, and unveil the presence of an epigenetic memory of inflammation in the pancreatic acinar cell compartment. We observe that de
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McVey, Mark J., Samia Saeed, Reda Siddiqui, et al. "The transfusion-associated dyspnea prospective observation and laboratory assessment study: a protocol for investigating and disambiguating cardiopulmonary and high-grade febrile transfusion reactions in adults." International Journal of Clinical Trials 10, no. 1 (2023): 56–65. http://dx.doi.org/10.18203/2349-3259.ijct20230051.

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Background: Cardiorespiratory transfusion reactions drive most transfusion-related morbidity and mortality. Transfusion-associated circulatory overload and transfusion-related acute lung injury have established causes, important impacts, mitigation options, and revised definitions, while non-conforming CRTRs fall into a category known as transfusion-associated dyspnea. Though procedures to investigate high-risk febrile transfusion reactions are typically rooted in detecting incompatibility or bacterial contamination, a common standard for examining CRTRs is lacking. CRTRs are further challenge
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Bhargav, P. R. K., V. Amar, C. H. Venkata Pavan Kumar, and K. B. Gayathri. "Pipestem Carotids as a Marker of Vascular Insult in Graves’ Disease." Indian Journal of Surgery 73, no. 2 (2010): 168–69. http://dx.doi.org/10.1007/s12262-010-0176-3.

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Lad, Nikita, Alice M. Murphy, Cristina Parenti, et al. "Asthma and obesity: endotoxin another insult to add to injury?" Clinical Science 135, no. 24 (2021): 2729–48. http://dx.doi.org/10.1042/cs20210790.

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Abstract Low-grade inflammation is often an underlying cause of several chronic diseases such as asthma, obesity, cardiovascular disease, and type 2 diabetes mellitus (T2DM). Defining the mediators of such chronic low-grade inflammation often appears dependent on which disease is being investigated. However, downstream systemic inflammatory cytokine responses in these diseases often overlap, noting there is no doubt more than one factor at play to heighten the inflammatory response. Furthermore, it is increasingly believed that diet and an altered gut microbiota may play an important role in t
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Santambrogio, Laura, Cristina C. Clement, Padma Nanaware, and Lawrence Stern. "METABOLIC INSULTS ELICIT EPITOPE-DEPENDENT IMMUNE AUTOREACTIVITY AGGRAVATING HEPATIC DAMAGE IN TYPE 2 DIABETES." Journal of Immunology 208, no. 1_Supplement (2022): 102.07. http://dx.doi.org/10.4049/jimmunol.208.supp.102.07.

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Abstract A diet rich in saturated fat and carbohydrates causes low-grade chronic inflammation in several organs including the liver, ultimately driving non-alcoholic steatohepatitis. The environment-driven lipotoxicity and glucotoxicity induces liver damage, which promotes dendritic cell adjuvanticity and generates an MHC-II immunopeptidome enriched of peptides derived from proteins involved in cellular metabolism, oxidative phosphorylation, and stress responses. Here, we demonstrate that metabolic insults promote the presentation of nested T and B cell epitopes from protein disulfide isomeras
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Isnawan, Fuadi. "Analysis Of Criminal Law Respect for Deceased Persons." Al-Jinayah : Jurnal Hukum Pidana Islam 10, no. 1 (2024): 134–63. https://doi.org/10.15642/aj.2024.10.1.134-163.

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Respect for individual rights is an important moral and legal foundation in maintaining justice and humanity in the criminal law system. Although the individual has passed away, complexities arise as their rights still need to be respected. A deceased individual's legacy, including reputation and social influence, remains relevant and influences society. This research aims to understand how the criminal law system, particularly in the Criminal Code (KUHP), handles cases involving deceased individuals, including the protection of their reputation and open legal liability. This research utilizes
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17

Kelly, Daniel F., Irene T. Gaw Gonzalo, Pejman Cohan, Nancy Berman, Ronald Swerdloff, and Christina Wang. "Hypopituitarism following traumatic brain injury and aneurysmal subarachnoid hemorrhage: a preliminary report." Journal of Neurosurgery 93, no. 5 (2000): 743–52. http://dx.doi.org/10.3171/jns.2000.93.5.0743.

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Object. Recognition of pituitary hormonal insufficiencies after head injury and aneurysmal subarachnoid hemorrhage (SAH) may be important, especially given that hypopituitarism-related neurobehavioral problems are typically alleviated by hormone replacement. In this prospective study the authors sought to determine the rate and risk factors of pituitary dysfunction after head injury and SAH in patients at least 3 months after insult.Methods. Patients underwent dynamic anterior and posterior pituitary function testing. Results of the tests were compared with those of 18 age-, sex-, and body mas
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Worley, Gordon, Brian Lipman, Ira H. Gewolb, et al. "Creatine Kinase Brain Isoenzyme: Relationship of Cerebrospinal Fluid Concentration to the Neurologic Condition of Newborns and Cellular Localization in the Human Brain." Pediatrics 76, no. 1 (1985): 15–21. http://dx.doi.org/10.1542/peds.76.1.15.

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Immunocytochemical study of human brain showed creatine kinase brain isoenzyme (CKBB) present in both neurons and astrocytes. Because creatine kinase brain isoenzyme is an intracellular enzyme that might be released with brain injury, its concentration in the CSF of newborns was measured using a radioimmunoassay. Infants who suffered a documented neurologic insult (a cerebroventricular hemorrhage or a CNS infection) were found to have a greater mean CSF creatine kinase brain isoenzyme concentration than those without a history of neurologic insult. Infants with a high concentration had a poor
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Wise, John C. "Grape, Season Long Broad Spectrum Insect Control, 1996." Arthropod Management Tests 22, no. 1 (1997): 55. http://dx.doi.org/10.1093/amt/22.1.55.

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Abstract Insecticides were applied to mature (16 year old) cv. ‘Concord’ grape vines at the Trevor Nichols Research Complex near Fennville, MI at a rate of 50 GPA using a FMC 1029 airblast sprayer. Treatments were arranged in a completely randomized design of single 50 ft long rows of vines replicated four times. Applications of materials were made on 28 Jun (Bloom, 725 Degree Days base 50 for GLH), 10 Jul (3C), 22 Jul (4C), 7 Aug (5C), 21 Aug (6C), 3 Sep (7C), and 16 Sep (8C). Grape leafhopper evaluations were made on 19 Jul and 15 Aug by randomly selecting 50 leaves per replicate, or 200 lea
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Wise, John C., and Larry J. Gut. "Grape, Season-Long Broad-Spectrum Insect Control, 1997." Arthropod Management Tests 23, no. 1 (1998): 54. http://dx.doi.org/10.1093/amt/23.1.54a.

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Maramorosch, Karl. "Thomas D. C. Grace—Insect tissue culture pioneer." Journal of Invertebrate Pathology 58, no. 2 (1991): 151–56. http://dx.doi.org/10.1016/0022-2011(91)90058-x.

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Young, Sandy. "INCOSE Spotlight on ‖ INCOSE Ambassador Grace Najjar." INSIGHT 15, no. 3 (2012): 51. http://dx.doi.org/10.1002/inst.201215351.

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Sampson, Blair, Steve Noffsinger, Creighton Gupton, and James Magee. "Pollination Biology of the Muscadine Grape." HortScience 36, no. 1 (2001): 120–24. http://dx.doi.org/10.21273/hortsci.36.1.120.

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Fruit set in the muscadine grape (Vitis rotundifolia Michx.) depended on insect cross-pollination, although flowers were well adapted for selfing. Pollinizer cultivars produced about half of their optimal fruit set when selfed, but cross-pollination was needed to reach an optimal fruit set of 33.7%. Eighty-one percent of the overall fruit set in pistillate vines was attributed to insect cross-pollination; wind played only a small role. Diminished fruit set and fewer seeds per berry occurred in cultivars receiving no effective cross-pollination. Components of fruit quality were not profoundly a
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Goetz, Jessica E., Young-Yool Chung, Dale L. Zimmerman, et al. "STEROID-INDUCED VERSUS CRYOINSULT-INDUCED FEMORAL HEAD OSTEONECROSIS: STATISTICAL MEASUREMENT OF HISTOLOGIC ABNORMALITY FOCALIZATION." Journal of Musculoskeletal Research 09, no. 04 (2005): 161–72. http://dx.doi.org/10.1142/s021895770500159x.

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Systematic studies of treatment options for femoral head osteonecrosis have been hindered by the lack of an animal model that mimics the human event of femoral head collapse. The (bipedal) emu model of osteonecrosis has proven to progress to collapse following an external insult. Since osteonecrosis clinically has multiple etiologies, various alternatives are seemingly appropriate to initiate lesions for research purposes. This study compared osteonecrosis initiated by a local cryoinsult, to that initiated by a large systemic dose of steroid (methylprednisolone acetate), and by a combination o
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Lasa, Rodrigo, Saide Aguas-Lanzagorta, and Trevor Williams. "Agricultural-Grade Apple Cider Vinegar Is Remarkably Attractive to Drosophila suzukii (Diptera: Drosophiliadae) in Mexico." Insects 11, no. 7 (2020): 448. http://dx.doi.org/10.3390/insects11070448.

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Due to its availability and low cost, apple cider vinegar (ACV) is a frequently used as an attractant for monitoring the invasive spotted wing drosophila, Drosophila suzukii. In laboratory cage experiments, the attraction of ACV alone was compared with ACV in mixtures with different concentrations of acetic acid, propionic acid, different hydrolyzed proteins, synthetic fruit flavors (strawberry, blackberry and apple) and the addition of fruit nectars (grape, pineapple and apple). The addition of 5% apple nectar to ACV significantly increased fly captures, whereas other combinations were simila
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McCutcheon, John P., Bret M. Boyd, and Colin Dale. "The Life of an Insect Endosymbiont from the Cradle to the Grave." Current Biology 29, no. 11 (2019): R485—R495. http://dx.doi.org/10.1016/j.cub.2019.03.032.

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Almairac, Fabien, Jeremy Deverdun, Jérôme Cochereau, et al. "Homotopic redistribution of functional connectivity in insula-centered diffuse low-grade glioma." NeuroImage: Clinical 29 (2021): 102571. http://dx.doi.org/10.1016/j.nicl.2021.102571.

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Mohammed, Youssif Ali, Qasim Ahmed, and Mokhtar Abdulsattar Arif. "Does grape leafhopper Arbordia hussaini (Hemiptera: Cicadellidae) effect on chlorophyll content of grape leaves?" IOP Conference Series: Earth and Environmental Science 1060, no. 1 (2022): 012121. http://dx.doi.org/10.1088/1755-1315/1060/1/012121.

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Abstract The leafhopper Arbordia hussaini is a phloem feeding pest of the grape leaves causing a drop in chlorophyll levels in the grape leaves, which decreases photosynthesis and causes drying of the leaves depend on the population density of insects and found in various grape varieties growing around the world. The direct effects of A. hussaini on biomass dynamics, particularly the chlorophyll content of grapevine leaves, are investigated in this study. the high population of A. hussaini were 19.33 insect adult per grape leave in the first of September, while the low density of A. hussaini w
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Ng, Yong Siang, Qing Ci Goh, Woh Wei Mak, et al. "MYELODYSPLASTIC SYNDROME AND GRAVES’ DISEASE." Journal of the ASEAN Federation of Endocrine Societies 38, S2 (2023): 64. https://doi.org/10.15605/jafes.038.s2.104.

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INTRODUCTIONMyelodysplastic syndrome (MDS) is a heterogeneous group of hematopoietic neoplasms characterized by bone marrow failure resulting in cytopenia and dysplastic haematopoiesis. The association between MDS and autoimmune diseases has been previously described in the literature. Here we report a case of Graves’ disease (GD) with secondary MDS. CASEA 43-year-old male with vitiligo was admitted for pancytopenia and left parapneumonic effusion. GD was concomitantly diagnosed based on weight loss, tachycardia, exophthalmos and the presence of TSH receptor antibodies. Antithyroid drugs were
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Haddadin, Sahel, Ahmad Mahasna, Ibrahim Abumekhleb, et al. "Comparison of Recurrent Laryngeal Nerve Insult Incidence Post Thyroidectomy for Benign and Malignant Lesions." Medical Archives 77, no. 3 (2023): 213. http://dx.doi.org/10.5455/medarh.2023.77.213-217.

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Background: Vocal cord paresis or paralysis caused by insult to the recurrent laryngeal nerve is one of the main hazards in thyroid surgery. The frequency of recurrent laryngeal nerve palsy varies between 1.5–20%. Hoarseness is found with unilateral recurrent laryngeal nerve insult (RLNI). Bilateral insult produces dyspnea and life-threatening glottal obstruction. The frequency of insult is more in re-do surgeries, Graves’ disease, and thyroid carcinoma operations. Objective: This study aimed to evaluate the risk factors of RLNI in thyroid surgery for benign or malignant lesions. Methods: This
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Mishra, Abhinab. "Modern Spraying Techniques For Grape Vineyards: A Review." African Journal of Biological Sciences 6, no. 10 (2024): 524–40. http://dx.doi.org/10.48047/afjbs.6.10.2024.524-540.

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During crop production, the most crucial techniques are being used for plant protection. Applying pesticides requires much more expertise and understanding than any other agricultural job, regardless of the crop being treated or the tools utilised. This is particularly applied to insect, disease, and mite control sprays in grapevines.
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Roper, Steven N., Michel F. Levesque, William W. Sutherling, and Jerome Engel. "Surgical treatment of partial epilepsy arising from the insular cortex." Journal of Neurosurgery 79, no. 2 (1993): 266–69. http://dx.doi.org/10.3171/jns.1993.79.2.0266.

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✓ Despite its documented connections with many limbic structures, the role of the insula in the etiology of partial seizures is poorly understood. Two patients are described in whom lesions of the insula were associated with intractable partial seizures. In the first patient, the seizures involved visceral sensory hallucinations followed by motor automatism. Seizures in the second patient began with somatic sensory hallucinations and then produced visceral motor effects. Both patients were found to have low-grade astrocytomas of the insula. In both instances, resection of the lesion and adjace
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Johnson, James W., Robert D. Kriegel, and John C. Wise. "Grape, Season-Long Broad-Spectrum Control, 1994." Arthropod Management Tests 20, no. 1 (1995): 50. http://dx.doi.org/10.1093/amt/20.1.50.

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Abstract Insecticides were applied to mature 14 year old grape vines at the Trevor Nichols Research Complex near Fennville, MI at a rate of 50 gpa using a FMC 1029 airblast sprayer. Treatments were arranged in a completely randomized design of single 50-foot-long rows of vines replicated 4 times. Insecticides were applied, as indicated in the table, on the following dates: 4 May (BS), 25 May (1C), 9 Jun (Bloom), 22 Jun (3C), 3 Jul (4C), 17 Jul (5C), 29 Jul (6C), 12 Aug (7C), 25 Aug (8C) and 6 Sep (9C). Second generation grape berry moth application was timed for one wk after sustained catch in
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Sch�tz, Ch R., F. W. Kreth, M. Faist, P. C. Warnke, B. Volk, and Ch B. Ostertag. "Interstitial 125-iodine radiosurgery of low-grade gliomas of the insula of Reil." Acta Neurochirurgica 130, no. 1-4 (1994): 80–89. http://dx.doi.org/10.1007/bf01405506.

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Nur, Rusdi, Arthur Halik Razak, Yosrihard Basongan, Muhira Dzar Faraby, Syahrisal Syahrisal, and Asrul Hidayat. "Effect of cutting process using cutting insert of grade UTi20T." International Journal of Advances in Applied Sciences 13, no. 2 (2024): 401. http://dx.doi.org/10.11591/ijaas.v13.i2.pp401-410.

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In the metal-cutting industry, the precision of the metal-cutting process is of paramount importance. Errors in the metal-cutting process not only lead to damage to the cutting tool but also result in the production of low-quality materials. The incorporation of insert materials in the cutting process is aimed at maintaining cutting precision and achieving superior results. This research seeks to investigate the impact of the cutting process utilizing grade KC5410 cutting insert under minimum quantity lubrication (MQL) Conditions. In this study, machining tests were conducted using the ALPHA 1
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Rusdi, Nur, Halik Razak Arthur, Basongan Yosrihard, Dzar Faraby Muhira, Syahrisal, and Hidayat Asrul. "Effect of cutting process using cutting insert of grade UTi20T." International Journal of Advances in Applied Sciences (IJAAS) 13, no. 2 (2024): 401–10. https://doi.org/10.11591/ijaas.v13.i2.pp401-410.

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In the metal-cutting industry, the precision of the metal-cutting process is of paramount importance. Errors in the metal-cutting process not only lead to damage to the cutting tool but also result in the production of low-quality materials. The incorporation of insert materials in the cutting process is aimed at maintaining cutting precision and achieving superior results. This research seeks to investigate the impact of the cutting process utilizing grade KC5410 cutting insert under minimum quantity lubrication (MQL) Conditions. In this study, machining tests were conducted using the ALPHA 1
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Gleadow, Roslyn, Jim Hanan, and Alan Dorin. "Averting robo-bees: why free-flying robotic bees are a bad idea." Emerging Topics in Life Sciences 3, no. 6 (2019): 723–29. http://dx.doi.org/10.1042/etls20190063.

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Food security and the sustainability of native ecosystems depends on plant-insect interactions in countless ways. Recently reported rapid and immense declines in insect numbers due to climate change, the use of pesticides and herbicides, the introduction of agricultural monocultures, and the destruction of insect native habitat, are all potential contributors to this grave situation. Some researchers are working towards a future where natural insect pollinators might be replaced with free-flying robotic bees, an ecologically problematic proposal. We argue instead that creating environments tha
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Gozé, Catherine, Lamisse Mansour, Valérie Rigau, and Hugues Duffau. "Distinct IDH1/IDH2 mutation profiles in purely insular versus paralimbic WHO Grade II gliomas." Journal of Neurosurgery 118, no. 4 (2013): 866–72. http://dx.doi.org/10.3171/2012.11.jns121100.

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Object The molecular profile of diffuse WHO Grade II gliomas involving the insular lobe, with a possible impact on outcome, is controversial. The authors undertook this study to investigate a possible difference of molecular patterns between purely insular Grade II gliomas and paralimbic Grade II gliomas that involve both the insular lobe and the frontal and/or temporal structures. Methods From a consecutive series of 47 patients who underwent resection of a Grade II glioma invading the insula, 2 subgroups were identified. The first subgroup included 11 patients with a purely insular tumor. Th
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Almairac, Fabien, Hugues Duffau, and Guillaume Herbet. "Contralesional macrostructural plasticity of the insular cortex in patients with glioma." Neurology 91, no. 20 (2018): e1902-e1908. http://dx.doi.org/10.1212/wnl.0000000000006517.

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ObjectiveTo assess the homotopic structural plasticity in case of unilateral damage of the insula.MethodsTo detect changes in gray matter volumes of the contralesional insula from structural MRIs, we used voxel-based morphometry (VBM) in a sample of 84 patients with a diffuse low-grade glioma invading the left insula (insL group; n = 47) or the right insula (insR group; n = 37).ResultsThe region of interest–based VBM analysis highlighted a large cluster of voxels with gray matter volume increase in the contralesional insula in both patient groups (k = 2,214 voxels for insL and k = 879 voxels f
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DEMIR, M., and M. H. ŞAHAN. "Evaluation of the relationship between trochlear and patellar morphology and patellar chondromalacia with magnetic resonance imaging." Acta Orthopaedica Belgica 89, no. 3 (2023): 409–16. http://dx.doi.org/10.52628/89.3.11782.

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It was aimed to investigate the relationship between magnetic resonance imaging (MRI) measurements of trochlear and patellar morphology and grade 3-4 patellar chondromalacia. Grade 3-4 patellar chondromalacia group, and an age- and sex-matched control group with normal patellar joint cartilage were comprised. For trochlear morphology evaluation in MRI; sulcus angle, trochlear angle, lateral trochlear inclination angle and medial trochlear inclination angle were measured. For patellar morphology evaluation; patella trochlear ratio, insall-salvati ratio, modified Insall- Salvati ratio and Blackb
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Zhao, Suisheng. "A State-Led Nationalism: The Patriotic Education Campaign in Post-Tiananmen China." Communist and Post-Communist Studies 31, no. 3 (1998): 287–302. http://dx.doi.org/10.1016/s0967-067x(98)00009-9.

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The decline of Communism after the end of the post-Cold War has seen the rise of nationalism in many parts of the former Communist world. In countries such as the former Soviet Union and Yugoslavia, nationalism was pursued largely from the bottom up as ethnic and separatist movements. Some observers also take this bottom-up approach to find the major cause of Chinese nationalism and believe that “the nationalist wave in China is a spontaneous public reaction to a series of international events, not a government propaganda.” (Zhang, M. (1997) The new thinking of Sino–US relations. Journal of Co
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Duffau, Hugues, Carine Karachi, Peggy Gatignol, and Laurent Capelle. "Transient Foix-Chavany-Marie Syndrome after Surgical Resection of a Right Insulo-opercular Low-grade Glioma: Case Reports." Neurosurgery 53, no. 2 (2003): 426–31. http://dx.doi.org/10.1227/01.neu.0000073990.94180.54.

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Abstract OBJECTIVE AND IMPORTANCE We describe an atypical case of transient Foix-Chavany-Marie syndrome, or faciopharyngoglossomasticatory diplegia with automatic voluntary dissociation, occurring after surgical resection of a right insulo-opercular glioma. CLINICAL PRESENTATION A 26-year-old right-handed man experienced partial seizures that were poorly controlled by antiepileptic drugs during a 2-year period as a result of a right insulo-opercular low-grade glioma, leading to the proposal of surgical resection. In addition, 1 year before the operation, the patient experienced a severe brain
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Hervey-Jumper, Shawn L., and Mitchel S. Berger. "Insular glioma surgery: an evolution of thought and practice." Journal of Neurosurgery 130, no. 1 (2019): 9–16. http://dx.doi.org/10.3171/2018.10.jns181519.

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OBJECTIVEThe goal of this article is to review the history of surgery for low- and high-grade gliomas located within the insula with particular focus on microsurgical technique, anatomical considerations, survival, and postoperative morbidity.METHODSThe authors reviewed the literature for published reports focused on insular region anatomy, neurophysiology, surgical approaches, and outcomes for adults with World Health Organization grade II–IV gliomas.RESULTSWhile originally considered to pose too great a risk, insular glioma surgery can be performed safely due to the collective efforts of man
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Zentner, Josef, Bernhard Meyer, Armin Stangl, and Johannes Schramm. "Intrinsic tumors of the insula: a prospective surgical study of 30 patients." Journal of Neurosurgery 85, no. 2 (1996): 263–71. http://dx.doi.org/10.3171/jns.1996.85.2.0263.

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✓ Intrinsic insular tumors are frequently excluded from surgical treatment. The authors propose a more extensive approach to these lesions based on the results of this prospective series. From September 1993 to January 1995, 30 patients (18 males and 12 females; mean age 42 years) harboring benign (15 patients) or malignant (15 patients) tumors involving the insula underwent surgical treatment. The dominant and nondominant hemispheres were both affected in 15 cases. Two groups were defined on the basis of preoperative magnetic resonance (MR) imaging: 14 lesions were restricted to the insula an
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Anderson*, Kathy Kelley. "Effect of Surround on Walnut Quality." HortScience 39, no. 4 (2004): 877A—877. http://dx.doi.org/10.21273/hortsci.39.4.877a.

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The effect of Surround® on walnut quality parameters including edible yield, reflected light index, insect damage, off grade, and price per pound were evaluated over a 3-year period in either, or in some years both, `Vina' and `Chandler' walnut orchards. Results indicate that edible yield, reflected light index, and price per pound were significantly increased by applications of Surround® in some years. Improvements in these parameters were more consistent with the cultivar `Vina'. Off grade was not significantly reduced by the use of Surround®. Insect damage levels were too low to measure in
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Tabouret, Emeline, Paloma Compes, Amandine Etcheverry, et al. "Molecular and neuro-radiological characteristics of diffuse grade II and III gliomas involving the insula." Journal of Clinical Oncology 36, no. 15_suppl (2018): e14050-e14050. http://dx.doi.org/10.1200/jco.2018.36.15_suppl.e14050.

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Nereu, Mauro, Ruben H. Heleno, Francisco Lopez-Núñez, Mário Agostinho, and Jaime A. Ramos. "Effects of native biodiversity on grape loss of four castes: testing the biotic resistance hypothesis." Web Ecology 18, no. 1 (2018): 15–27. http://dx.doi.org/10.5194/we-18-15-2018.

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Abstract. Management of agricultural landscapes can influence the biodiversity and the ecological services provided by these ecosystems, such as natural biological pest control. Viticulture is a very important economic activity in most countries with Mediterranean climate, often shaping their landscapes and culture. Grape production is affected by a number of pests and diseases, and farmers use prophylactic and response-driven pesticides to control these pests. Here we quantified the main biotic causes of crop losses in four grape castes, two red (Touriga Nacional and Baga) and two white (Arin
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Rotondo Dottore, Giovanna, Ilaria Bucci, Giulia Lanzolla, et al. "Genetic Profiling of Orbital Fibroblasts from Patients with Graves’ Orbitopathy." Journal of Clinical Endocrinology & Metabolism 106, no. 5 (2021): e2176-e2190. http://dx.doi.org/10.1210/clinem/dgab035.

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Abstract Context Graves’ orbitopathy (GO) is an autoimmune disease that persists when immunosuppression is achieved. Orbital fibroblasts from GO patients display peculiar phenotypes even if not exposed to autoimmunity, possibly reflecting genetic or epigenetic mechanisms, which we investigated here. Objective We aimed to explore potential genetic or epigenetic differences using primary cultures of orbital fibroblasts from GO and control patients. Methods Cell proliferation, hyaluronic acid (HA) secretion, and HA synthases (HAS) were measured. Next-generation sequencing and gene expression anal
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Graves, Joshua D., Yu-Ju Lee, Kang Liu, Gang Li, Fang-Tsyr Lin, and Weei-Chin Lin. "E2F1 sumoylation as a protective cellular mechanism in oxidative stress response." Proceedings of the National Academy of Sciences 117, no. 26 (2020): 14958–69. http://dx.doi.org/10.1073/pnas.1921554117.

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Oxidative stress is a ubiquitous threat to all aerobic organisms and has been implicated in numerous pathological conditions such as cancer. Here we demonstrate a pivotal role for E2F1, a cell cycle regulatory transcription factor, in cell tolerance of oxidative stress. Cells lacking E2F1 are hypersensitive to oxidative stress due to the defects in cell cycle arrest. Oxidative stress inhibits E2F1 transcriptional activity, independent of changes in association with Rb and without decreasing its DNA-binding activity. Upon oxidative insult, SUMO2 is extensively conjugated to E2F1 mainly at lysin
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Iizuka, Hideaki, Teiji Yamamoto, Yuzo Iwasaki, Hidehiko Konno, and Satoru Kadoya. "Experimental spinal cord injury: quantitation of axonal damage by automated image analysis." Journal of Neurosurgery 64, no. 2 (1986): 304–8. http://dx.doi.org/10.3171/jns.1986.64.2.0304.

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✓ The severity of acute experimental spinal cord injury in rats was assessed quantitatively with the aid of an automated image analyzer by measuring the amount of degenerating axons that had developed distal to the site of mechanical insult. Spinal cord injury was produced in adult male rats by epidural compression at T-11 with a Biemer vascular clip. On the 7th postoperative day, the animals were graded according to the degree of hindlimb motor deficit, as follows: Grade 0: normal (three rats); Grade 1: crawling with difficulty (10 rats); Grade 2: some voluntary movement (nine rats); and Grad
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