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Nylen, Emil, and Daniel Stolt. "CAPM - en vingklippt modell? : En kvantitativ studie om betavärdets påverkan på Sverigefonders avkastning." Thesis, Umeå universitet, Företagsekonomi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-105910.
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Idag äger många svenskar andelar i olika fonder. Detta beror delvis på att det allmänna pensionssystemet i Sverige idag består av en premiepensionsdel, där individen kan göra ett individuellt val hur dennes pensionspengar ska investeras. Gemensamt för investerare är att de vill erhålla en god avkastning. Ett vanligt sätt att bedöma förväntad avkastning i en finansiell tillgång kallas Capital Asset Pricing Model, eller CAPM. Detta är en mycket behandlad, debatterad och även kritiserad modell. Förutom CAPM utgår studien från en nyare teori som heter Black Swan theory. År 2007 presenterade Taleb sin teori om Black Swan. Han menar att en Black Swan är en händelse som avviker från det normala, har långtgående effekter och som efteråt får naturliga förklaringar. Ett potentiellt Swan-fenomen är finanskrisen. Om nu finanskrisen kan räknas som ett Swan-fenomen innebär det att den finansiella verkligheten har förändrats. Om nu den finansiella världen har påverkats så finns det anledning att tro att även modeller och deras överensstämmelse med verkligheten har påverkats. Det är detta vi i denna studie ämnar att undersöka och mynnar därför ut i frågeställningen: Var CAPM en fungerande modell gällande Sverigefonder åren 2005-2014? Studiens syfte lyder enligt följande: Att undersöka hur väl CAPM:s prediktion av förväntad avkastning i Sverigefonder stämmer överens med den faktiska avkastningen. Vi vill också genom undersökningen se ifall denna överensstämmelse har förändrats under vår undersökningsperiod och ifall detta i sådana fall kan kopplas till ett potentiellt Swan-fenomen som finanskrisen. Med teoretisk utgångspunkt i modern portföljvalsteori, CAPM och Black Swan theory undersöks sambandet mellan betavärde och avkastning i Sverigefonder. Vi utgår från en positivistisk kunskapssyn och genom en deduktiv ansats genomförs en regressionsanalys för att svara på vår frågeställning. Det empiriska materialet består av månadsavkastning från de valda fonderna, riskfri ränta och marknadsindexets avkastning. I vår studie hade vi endast ett år med signifikant positivt samband mellan beta och avkastning (som försvann i och med heteroskedasticitet i datamaterialet). Vi hade däremot ett år med negativt signifikans (2014) samtidigt som en positiv marknad, vilket inte överensstämmer med tidigare empiriska undersökningar. Vissa år ser det ut som att det finns samband genom att grafiskt titta på våra figurer i resultatdelen, men det är även år där det motsatta förhållandet finns. Med resultaten och analysen i åtanke kan vi inte förkasta nollhypotesen 2005-2013 (det finns inget samband mellan beta och avkastning).
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Kowalewski, Damian. "Edge-based encoding of gray-scale images." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=80305.
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This thesis explores image compression based on visual information contained within the edges. This work is based on an observation that not all the information contained within an image is used by the human brain. Previous works demonstrate methods for reconstructing images adequately using edge information. We exploit the fact that some components of the image can be removed while having little effect on human perception: this is the key basis for the compression developed in this thesis. We first construct compression preserving all the edge information extracted from the image. We then consider the impact of removing some of the edge information to further improve the compression ratio. We direct our attention to two types of information associated with edges: (1) its location and shape, (2) intensity and blur values on each side of the edge. First we propose a method to encode edge location and shape in a most efficient manner. We propose a measure of redundancy to remove edges carrying information already encoded in neighboring edges. Then we consider the compression of intensities and blur associated with each edge. Since the intensity information is quite noisy we show that we can remove the noise and reduce intensity functions to linear functions without significant impact on the quality of a reconstructed image. Finally we introduce a method to encode pattern information not included in edge information to improve the overall quality of the reconstructed image.
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Rault, Jasmine. "Eileen Gray : new angles on gender and sexuality." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=102825.
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This dissertation investigates the early twentieth century work of Irish-born interior designer and architect, Eileen Gray. While the existing literature has tended to read Gray and her work primarily in relation to major male modernist movements and figures, this dissertation contends that considering her engagement with the alternative modernisms developed by other women artists and writers at the time will enrich our understanding of the wider social, cultural and historical implications of her work. In order to make sense of what scholars have long recognised as Gray's critically different architecture and design I analyse her work in relation to three of her female contemporaries: the artist Romaine Brooks, and writers Radclyffe Hall and Djuna Barnes. Such an analysis reveals that Gray's critically different work was importantly related to the critically different aesthetics, genders and sexualities that Gray and many of her female contemporaries cultivated at the time.The first chapter argues that debates about domestic architecture and design were also importantly debates about modern bodies and subjects and provides the framework for the analyses that follow. Chapter 2 compares Gray's early lacquer works, La Voie Lactee (ca. 1912), Le Magicien de la Nuit (1913) and Le Destin (1914) to Romaine Brooks' two paintings from 1910, White Azaleas and The Screen, focusing on their use of decadent aesthetics. Chapter 3 considers Gray's first intricately designed house, E.1027 (1928), in relation to the content and cultural impact of Radclyffe Hall's 1928 novel, The Well of Loneliness. Chapter 4 examines Gray's extremely private and less known house, Tempe a Pailla (1934), in relation to the obscure and non-communicative narrative strategies of Djuna Barnes' 1936 novel, Nightwood. Overall, the argument that binds my dissertation is that Gray's work both contributed and responded to changing conceptions of gendered and sexual subjects in the first half of the last century.
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Höveler-Müller, Michael. "Funde aus dem Grab 88 der Qubbet el-Hawa bei Assuan : (die Bonner Bestände) /." Wiesbaden : Harrassowitz, 2006. http://catalogue.bnf.fr/ark:/12148/cb41080917g.
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Aryee, Alberta Naa Ayeley. "Extraction, partial purification and characterization of the lipase fraction from the viscera of grey mullet (Mugil cephalus)." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97895.
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Lipase was partially purified from the viscera of grey mullet ( Mugil cephalus) by ammonium sulfate fractionation, simultaneous desalting, and concentration via ultrafiltration and then affinity chromatography on EAH-Sepharose 4B. The partially purified extract was characterized using p-nitrophenyl palmitate (rho-NPP) as substrate. Grey mullet lipase was active within the pH range of 7-10, with an optimum pH of 8.0, and was stable from pH 4-10. The enzyme was active within the temperature range of 20°C and 60°C, and exhibited an optimum for the hydrolysis of rho-NPP at 50°C. The enzyme was stable between 10-50°C, beyond which it lost activity progressively. At 50°C there was ca. 50% residual activity after 60 min incubation. However at 60°C, there was 22%, 20% and 0% remaining activity after 10, 30 and 60 min incubation respectively. Based on the temperature activity data, the activation energy for the hydrolysis of rho-NPP was calculated as 1.94 kcal/mol (8.15 kJ/mol).The rho-nitrophenyl esters of medium to long chain fatty acid (C10-C16) served as good substrates with the order of ease of hydrolysis as; rho-NP-palmitate > rho-NP-myristate > rho-NP-caprate > rho-NP-caproate > rho-NP-butyrate > rho-NP-acetate. The Km' and Vmax for the hydrolysis of rho-NPP were 0.22 mM and 20 mumol min-1 mg-1 , respectively. The hydrolytic activity of the lipase was enhanced by Mg2+, Mn2+, NaN3, and EDTA, but strongly inhibited by Hg2+, and Cu2+. PMSF (1 mM), Ca2+ (1 mM and 10 mM) had no effect on grey mullet lipase activity. Lower concentrations (25-10% v/v) of water-miscible organic solvents (dimethyl sulfoxide, dimethyl formamide, iso-propanol, and methanol) had negligible effect on the activity of the lipase while higher concentrations (>50% v/v) completely inhibited the enzyme. The grey mullet lipase was remarkably stable in water-immiscible organic solvents (benzene, toluene, hexane, heptane, and isooctane). The water-immiscible solvents also activated the enzyme with hexane giving the most activation. Lower concentrations of trihydroxylated bile salts (sodium taurocholate, and sodium cholate) were more potent activators than the dihydroxylated bile salt (sodium deoxycholate). Sodium dodecyl sulfate at 1 mM, and Tween 80RTM at 1% had 6% and 12% stimulatory effect on the activity of the enzyme respectively, while 1% and 0.5% Triton RTM X-100 caused 67% and 40% inhibition, respectively.
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Mohr, Alexandra. "Use of a monoclonal antibody to detect gray mold (Botrytis cinerea) in strawberry." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33812.
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Gray mold, caused by Botrytis cinerea is the major cause of postharvest loss in strawberries. Detection of flower and fruit infections enables producers to make intelligent management decisions. A plate-trapped ELISA protocol using a Botrytis-specific monoclonal antibody (BC-12.CA4) was developed for the detection of Botrytis cinerea in strawberry flower receptacles and red fruits. Horseradish peroxidase, was chosen as enzyme conjugate because it gave lower background absorbance in disease-free samples. B. cinerea reference antigen (RAg) was isolated from strawberry. BC-12.CA4 was very sensitive to the RAg, detecting up to 6 mug/ml of RAg when mixed with strawberry extracts. The MAb did not show any reaction to Rhizopus sp., Mucor sp. and Penicillium sp. associated with strawberry. B. cinerea could be detected in receptacles two days after inoculation. Treatment of inoculated receptacles with paraquat speeded-up detection. Inoculated red fruit infection could be detected after three days of incubation. Disease in commercially-produced receptacles and red fruits were assessed visually and by ELISA. The ELISA detected B. cinerea in 95% of commercial flower samples, whereas the traditional visual method detected only 50 to 70%. No dramatic differences between methods were found for red fruits.
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Radhi, Ohood Aqeed. "Xenophagy in response to Gram-positive Staphylococcus aureus and Gram-negative Salmonella enterica sv. Typhimurium." Thesis, University of Strathclyde, 2018. http://digitool.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=30530.
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Autophagy is an important process for cell survival in the human body, which plays a critical role in fighting infections. Some infections exploit the autophagic system and are often promoted by autophagy. Recent evidence has suggested that Staphylococcus aureus has specialised mechanisms to evade xenophagy, thus allowing bacterial survival and replication within autophagosomes, leading to eventual cell death. ULK1 is a serine/threonine kinase that plays an essential role during the early steps of autophagosome biogenesis, but its roles during xenophagy following Staphylococcus aureus infection have been unclear. ULK1 represents an excellent candidate for drug targeting to control autophagy under various settings. This study aimed to investigate the role of autophagy in defence against two disease causing bacteria that are known for their ability to damage cells: Salmonella entericasv. Typhimurium and Staphylococcus aureus. A further aim was to study the role of the ULK1 complex in xenophagy following infection by Staphylococcus aureus and furthermore to test ULK1 inhibitors as a novel therapy to restrict MRSA infection in cells. In addition, in this project, CRISPR genetic selection approaches were developed, aimed to find new host cell genes required for Staphylococcus aureus and Salmonella enterica sv. Typhimurium infection. The results indicated two different roles of autophagy: 1) to provide a protective niche for MRSA, and 2) to provide a mechanism to fight infection by Salmonella enterica sv. Typhimurium. Importantly, treatment of cells with a ULK1/2 small molecule inhibitor strongly inhibited cell killing following infection by MRSA. However, ULK1/2 inhibition made cells more sensitive to cell death following infection by Salmonella enterica sv. Typhimurium. Thus, ULK1 inhibitors may be a novel therapeutic method for fighting infection by MRSA.Also, in this project, we found that screening with a freely available CRISPR-Cas9 library successfully identified the host genes essential for the toxicity of cells by MRSA(NCTC8325) or Salmonella enterica sv. Typhimurium. This was confirmed byfunctional validation and may open the door for novel putative therapeutic targets in future.
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Ghosh, Alak 1970. "The identification of neurite growth inhibitory activity in the adult rat CNS gray matter." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=23891.
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The aim of this work was to determine whether adult rat cerebral cortical gray matter membranes possess neurite growth inhibitory activity and to characterize this, if present.Tissue culture substrates of detergent extracted cortical gray matter membrane proteins inhibited neurite outgrowth from NG108-15 cells. Cortical gray matter membranes also caused growth cone collapse of embryonic rat dorsal root ganglion neurons. The inhibitory activity was both heat and trypsin sensitive suggesting the involvement of protein(s). Western blots and enzyme treatments indicate that known inhibitors are unlikely to contribute to this activity. The activity did not bind specifically to either Concanavalin A, peanut agglutinin, or wheat germ agglutinin. Ion-exchange chromatographic separation of the extracts suggests the presence of multiple inhibitory molecules.
These results suggest that adult rat cortical gray matter contains neurite growth inhibitory activity, possibly due to contributions from several as yet uncharacterized inhibitory molecules.
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Hervieux, Meggy. "Factors affecting defoliation of eastern hemlock (Tsuga canadensis) by the pale-winged gray moth (Iridopsis ephyraria)." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=106455.
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The main objective of this thesis was to study the possible factors that could explain the feeding preference of the pale-winged gray moth (PWG) (Iridopsis ephyraria) for the mid-lower crown of eastern hemlocks in south-west Nova Scotia. I first described egg and larval distribution between crown locations of mature hemlocks. I then focused on testing two hypotheses that could explain the pale-winged gray feeding preference for the foliage located in the mid-lower crown: (1) hygrothermal and (2) foliage quality hypotheses. My research shows that eggs and larvae were principally located in the mid-lower crown. This larval preference could partly explain the greatest defoliation in the mid-lower crown of mature hemlocks. Experimental and observational data revealed that both hygrothermal stress and foliage quality varied between crown locations and thus affected the PWG feeding preference. The disadvantages of heat and water stress in the upper crown, however, outweighed the benefits to feed on higher foliage quality which explains the PWG feeding preference for foliage in the mid-lower crown. Additional data on foliage age showed that larvae prefer to feed on current-year foliage presumably because this age-class had higher water and nitrogen content. This feeding preference may have helped larvae to survive in the upper crown where temperatures are warmer. This research adds to the literature on plant-insect interactions, allows a better understanding of the pale-winged gray moth natural history but mostly, informs us on the factors that affect PWG survival.Récemment, la région sud-ouest de la Nouvelle-Écosse a été sévèrement touchée par l'arpenteuse à tâches (Iridopsis ephyraria), un lépidoptère s'attaquant principalement à la Pruche du Canada (Tsuga canadensis). L'objectif principal de ce mémoire était d'explorer les facteurs pouvant expliquer la préférence alimentaire de l'arpenteuse à tâches pour le feuillage retrouvé dans la couronne inférieure des pruches du Canada. En premier lieu, j'ai décrit la distribution des oeufs et des larves de l'arpenteuse à tâches entre les différentes strates des pruches matures. J'ai ensuite vérifié différentes hypothèses pouvant expliquer la distribution verticale de l'espèce dans la canopée : (1) la variation du microclimat (i.e. température et humidité) ainsi que (2) les changements dans la qualité du feuillage. Les oeufs et les larves de l'espèce étaient principalement localisés dans la partie inférieure de la canopée. La défoliation plus importante au niveau de la couronne inférieure des arbres matures pourrait, en partie, être expliquée par cette préférence chez les larves. Dans le chapitre 3, mes résultats ont démontré que le stress hydrique (stress causé par une température élevée et un faible taux d'humidité) ainsi que la qualité du feuillage ont influencé la préférence alimentaire de l'arpenteuse à tâches. Toutefois, les effets négatifs du stress hydrique ont davantage influencé la distribution finale de l'espèce dans les pruches du Canada comparativement aux effets reliés à la qualité du feuillage. De plus, mes données ont révélé que l'arpenteuse à tâches préfère se nourrir sur le feuillage de l'année courante qui comporte plus d'eau et d'azote. Cette préférence pour le feuillage de l'année courante pourrait favoriser la survie des larves retrouvées dans le haut de la canopée où le stress hydrique est supérieur. Ce projet a permis d'ajouter à la littérature scientifique de l'information sur les relations entre plantes et insectes. Ce mémoire permet aussi de comprendre davantage l'histoire naturelle de l'arpenteuse à tâches mais surtout, il nous informe sur les facteurs qui affectent la préférence alimentaire de l'espèce dans les pruches matures.
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Sulzbach, Carla. "David Zvi Hoffmann's Die Wichtigsten Instanzen gegen die Graf- Wellhausensche Hypothese : ("The main arguments against the Graf-Wellhausen hypothesis"):." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=24106.
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It is the aim of Part I of this thesis, the Introduction, to introduce David Zvi Hoffmann (1843-1921) in his capacity of a Bible scholar and a critic of 19th century German biblical criticism. Ample attention will be devoted to Hoffmann's own background, his German environment as well as that of Wellhausen. This will cover Sections I and III of the Introduction respectively. In order to be able to place Hoffmann's work within the proper context, Section II of the Introduction will explore the history of the general critical reception of the Hebrew Bible in the various cultures and eras where it played a role as well as its interaction with intellectual developments. Part II contains an annotated translation of Hoffmann's attack on Wellhausen's "documentary hypothesis."
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Leite, Diana Valquíria Teixeira Costa. "Estudo de curvas de 3º e 4º grau segundo Gomes Teixeira." Dissertação, Porto : Universidade do Porto, Faculdade de Ciências, Departamento de Matemática Pura, 2007. http://catalogo.up.pt/F?func=find-b&local_base=FCB01&find_code=SYS&request=000098625.
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Martins, Isabel Alexandra da Silva. "Grau de atençao em saúde oral na grávida." Dissertação, Porto : [s.n.], 2000. http://catalogo.up.pt/F?func=find-b&local_base=UPB01&find_code=SYS&request=000099727.
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BEUTLER, Sidinei Julio. "Organossolos: fun??es de pedotransfer?ncia para densidade do solo, avalia??o do grau de subsid?ncia, e estoques de carbono." Universidade Federal Rural do Rio de Janeiro, 2016. https://tede.ufrrj.br/jspui/handle/jspui/1987.
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CAPES
The Histosols are a major source of carbon storage in terrestrial environments and have high susceptibility to carbon losses when disturbed. The objective of this study was to generate pedotransfer functions (FPT) to assess the accuracy of previously published equations, applying them to predict soil bulk density (Bd) in organic soils from Brazil; to evaluate subsidence rate, and the variation of Bd and carbon of humic substances in Histosols over a period of one year; and to estimate stock and potential loss of carbon in Histosols from Rio de Janeiro State. For the first part of the study, there were used organic horizons, i.e., soil materials with total organic carbon (TOC) equal to or greater than 80 g kg-1 soil, totaling 280 horizons from different regions of Brazil. It was used the multiple linear regression technique and the equations were validated on independent data. There were tested 9 equations already published in the literature. The equations with better performance were the Hollis and FPT2, with R2 validation parameters of 0.48 and 0.49. When the clay fraction data is availlable, it is recommended to use the FPT1 equation; if there is no data on clay it is recommended the FPT2 and Hollis equations, which have only the TOC as a predictor variable. For the second part, a greenhouse experiment was carried out. For that, undisturbed samples were collected using PVC pipes, of two profiles of Organossolos Tiom?rficos, one in the neighborhood of Santa Cruz (SC Profile), city of Rio de Janeiro, and one in Mag? (Profile MG) municipality. There were evaluated 3 drainage levels, at 30, 60, and 100 cm deep, with 5 measuremts over time, being 0, 90, 180, 270, and 360 days (4 replicates). The MG profile presented the highest rates of subsidence, reaching 1.30 cm year-1 for the 100 cm drainage. Bd increased over time for both profiles, and the deeper drainage increased values in the SC profile. The deeper drainage favored the reduction of pH for both profiles. The TOC showed a decreasing trend over time. The values of carbon in the fulvic acid fraction (FAF), humic acid fraction (HAF), and humin fraction (HUM) showed no differences according to drainage levels. However, over time they showed high sensitivity to temperature changes, showing high levels of FAF and HAF at the end period and a consequent reduction in humin fraction. For the third and final section, there were used 43 soil profiles, where 18 of them did not have bulk density data, which were estimated by the FPTs. Comparisons between measured and estimated data groups was performed using the Wilcoxon test. The spatial distribution of the variables was performed using the IDW interpolation method. The average values of TOC was 228.0 g kg-1, Bd was 0.48 Mg m-3, the thickness of the profiles was 86 cm, the depth was 90 cm and the average stock TOC was 73.51 kg m-2. The spatialization showed qualitative differences for the variables in the different profile locations. The estimated TOC stock for the profiles form RJ State was 27,178,631.8 Mg. The estimated rates of loss were 10.87 kg m-2 for Histosols more recently drained and high TOC; of 7.16 kg m-2 for intermediate drained Histosols; and 1.46 kg m-2 for Histosols with longer time after drainage and low TOC. Soils with high TOC levels are more likely to have high losses TOC when disturbed.
Os Organossolos s?o uma importante fonte de estoque de carbono nos ambientes terrestres e possuem alta suscetibilidade ?s perdas de carbono quando perturbados. O objetivo do presente trabalho foi gerar equa??es, avaliar a acur?cia de equa??es j? publicadas, aplicando-as para a predi??o da densidade do solo (Ds) em solos org?nicos do Brasil; avaliar a taxa de subsid?ncia, a varia??o da Ds, e o carbono das subst?ncias h?micas em Organossolos ao longo do per?odo de um ano; e estimar o estoque e as potenciais perdas de carbono nos Organossolos do Estado do Rio de Janeiro. Para a primeira parte, trabalhou-se com horizontes org?nicos, i.e., materais de solo com teores de carbono org?nico total (COT) iguais ou maiores que 80 g kg-1 de solo, totalizando 280 horizontes em diferentes regi?es do Brasil. Foi empregada a t?cnica de regress?o linear m?ltipla e as equa??es foram validadas sobre dados independentes. Foram testadas 9 equa??es j? publicadas na literatura. As equa??es com melhor desempenho foram FPT2 e Hollis, com par?metros de valida??o R2 de 0,48 e 0,49. Em casos onde os teores de argila estejam quantificados, recomenda-se a equa??o FPT1, e na sua aus?ncia recomenda-se as equa??es FPT2 e Hollis, que possuem somente o COT como vari?vel preditora. Para a segunda parte, realizou-se um experimento em casa de vegeta??o. Foram coletadas amostras indeformadas em tubos de PVC, de dois perfis de Organossolo Tiom?rfico, sendo um no bairro Santa Cruz (Perfil SC), munic?pio de Rio de Janeiro, e outro no munic?pio de Mag? (Perfil MG). Foram avaliados 3 n?veis de drenagem, sendo de 30, 60, e 100 cm de profundidade, 5 avalia??es ao longo do tempo, sendo de 0, 90, 180, 270, e 360 dias (com 4 repeti??es). O perfil MG apresentou as maiores taxas de subsid?ncia, chegando a 1,30 cm ano-1 para a drenagem de 100 cm. A Ds aumentou ao longo do tempo para os dois perfis, e a drenagem mais profunda aumentou os valores no perfil SC. A drenagem mais profunda favoreceu a redu??o do pH para os dois perfis. Os teores de COT apresentaram tend?ncia de redu??o ao longo do tempo. Os valores de carbono da fra??o ?cido f?lvico (FAF), fra??o ?cido h?mico (FAH), e fra??o humina (HUM), n?o mostraram diferen?as de acordo com os n?veis de drenagem. No entanto, ao longo do tempo, apresentaram alta sensibilidade ?s varia??es de temperatura, mostrando elevados teores de FAF e FAH no per?odo final, e a consequente redu??o dos teores de HUM. Para a terceira e ?ltima parte do estudo, foram usados 43 perfis de Organossolos, sendo que 18 deles n?o apresentavam os dados de densidade do solo (Ds), os quais foram estimados por meio de FPTs. As compara??es entre os grupos de dados medidos e estimados foi feita pelo teste de Wilcoxon. A espacializa??o das vari?veis foi realizado atrav?s do m?todo de interpola??o IDW. Os valores m?dios de COT foi de 228,0 g kg-1, a Ds foi de 0,48 Mg m-3, a espessura dos perfis foi de 86 cm, a profundidade foi de 90 cm, e o estoque m?dio de COT foi de 73,51 kg m-2. A espacializa??o mostrou diferen?as qualitativas para as vari?veis nos diferentes locais. Foi estimado um estoque de COT de 27.178.631,8 Mg para os Organossolos do Estado do RJ. As taxas estimadas de perdas foram de 10,87 kg m-2 para Organossolos com drenagem mais recente e altos teores de COT; de 7,16 kg m-2 para Organossolos intermedi?rios; e 1,46 kg m-2 para Organossolos com menores teores de COT e longo tempo de drenagem. Solos com altos teores de COT est?o mais propensos a terem altas perdas de COT quando perturbados.
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Pinchuk, Tommy. "Optimization of pre-processing variables for hyperspectral analysis of focal plane array Fourier transform infrared images." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=98769.
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A genetic algorithm was employed to select the optimal combination of preprocessing variables, including data pretreatment, data manipulation and feature extraction procedures, for eventual clustering of a data set consisting of hyperspectral images acquired by a focal plane array Fourier transform infrared (FPA-FTIR) spectrometer. The data set consisted of infrared images of bacterial films, and the classification task investigated was the discrimination between Gram-positive and Gram-negative bacteria. The genetic algorithm evaluated combinations of variables pertaining to bacterial film thickness tolerances, baseline correction, pixel co-addition, outlier removal, smoothing, mean centering, normalization, derivatization, integration and principal component selection. Following numerous iterations of unsupervised processing, the genetic algorithm arrived at a sub-optimal solution yielding a clustering accuracy of 97.8% and a data utilization of 28.6%. The results provided insight into the co-dependencies of the pre-processing variables and their consequential effect on the selected data. The robustness of the classification model was evaluated and reinforced by the successful classification of two distinct validation sets. The overall success of the genetic algorithm suggests that it is an effective time saving resource for the optimization of pre-processing variables that does not require operator intervention.
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Wood, Claire M. "A molecular analysis of the potassium efflux system KefC." Thesis, University of Aberdeen, 1996. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU530038.
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KefB and KefC are glutathione-gated potassium channels that play a protective role during the detoxification of electrophiles in Gram negative bacteria. The KefC channel from Klebsiella aerogenes has been characterised and the gene cloned and sequenced. The KefC channel from K. aerogenes is analogous to KefC from Escherichia coli. The electrophile compounds NEM and CDNB are strong activators of potassium loss via the channel, whereas, methylglyoxal is a weak activator of potassium loss. At the amino acid level the putative protein shows a high degree of similarity with KefC from E. coli. While sequencing the kefC gene from K. aerogenes a difference in the genome organisation of K. aerogenes and E. coli was observed, highlighting the presence of an unassigned ORF, yabF, that overlaps the kefC by 8 bp. Clones of the K. aerogenes kefC gene that lack the first 129 bp of yabF exhibit reduced KefC activity. Analysis of the sequence surrounding the kefB gene from E. coli revealed an ORF, yhaH, that encodes a homologue of the putative YabF protein. The amino acid distribution of YabF and YhaH predict soluble proteins with significant similarity to the NAD(P)H dehydrogenase quinone oxidoreductase, DHQV. To investigate the function of YabF, a strain lacking the yabF-kefC region in E. coli was constructed. The strain was transduced into a kefB background and when transformed with a plasmid expressing only KefC channel activity was greatly reduced. The data suggest that the YabF protein is required in trans for the activity of KefC and preliminary evidence from in vitro-galactosidase fusion studies suggest that yabF and kefC genes may form an operon.
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Quintin, Jessica. "Study of the GNBP/ßGRP family in the immune response of the fruit fly Drosophila melanogaster and of the host-pathogen interaction between this host and opportunistic fung Candida." Strasbourg, 2009. http://www.theses.fr/2009STRA6218.
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La réponse humorale induite suite à une infection joue un rôle crucial dans le système immunitaire de la Drosophile. Deux voies de signalisation de type NF-κB contrôlent cette réponse, la voie Toll et la voie IMD. Durant mon doctorat, j'ai dans un premier temps étudié les mécanismes impliqués dans la détection des infections microbiennes, mécanismes qui commençaient juste à être caractérisés. Alors que les Pattern Recognition Receptors appartenant aux familles des Toll-Like Receptors et des Peptidoglycan Recognition Proteins interagissant avec les ligands microbiens sont bien décrits, rien n’était connu sur la reconnaissance des motifs microbiens par les Gram-Negative Binding Proteins. J'ai aussi essayé de caractériser des nouveaux effecteurs de l’immunité en plus des peptides antimicrobiens, lesquels ont été extensivement étudiés par le passé. Dans une deuxième partie de mon travail de thèse, j'ai caractérisé les interactions qui ont lieu entre la Drosophile en tant qu’hôte et les microbes comme la levure opportuniste Candida glabrata. De façon général cette étude a établi la pertinence particulière de la Drosophile comme modèle d’étude des interactions entre l'hôte et les champignons, qui représentent un défi majeur pour les années à venir. La voie est maintenant ouverte pour de nouveaux travaux sur ce modèle d’étude des relations hôtes-pathogènesThe inducible humoral response plays a crucial role in the Drosophila immune system. It is controlled by two major NF-κB signalling pathways, Toll and IMD, which have been extensively studied. During my PhD I first studied the mechanisms involved in detecting microbial infection, which just started to be characterized at this time. Whereas it is now understood how Pattern Recognition Receptors from the Toll-Like Receptor and Peptidoglycan Recognition Protein families interact with microbial ligands, nothing was known about the sensing of microbial patterns by the Gram-Negative Binding Proteins. I have also attempted to characterize novel immune effectors in addition to the antimicrobial peptides, on which attention has mainly focused in the past. In a second part, I deciphered the interactions that take place between the host Drosophila and microbes such as the opportunistic fungi C. Glabrata. Overall, this study established the particular relevance of Drosophila as an exciting model for understanding the interactions between host and fungi, which will be a major challenge for the years to come. The stage is now set for further studies on this instructive model of host-pathogen relationships
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Yu, Sai Hung. "The origin of the lipopolysaccharide in the periplasmic space fraction of Alteromonas haloplanktis 214 /." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=55685.
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Cai, Jie. "Identification and characterization of a chromosomal arsenicantimony inducible operon in gram-negative bacteria." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=34707.
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In searching for genetically-programmed responses to arsenic oxyanion exposure in plasmid-free bacterial strains, an arsenate-inducible Escherichia coli chromosomal operon was identified using a Mud I (lac Apr) transposable bacteriophage. The operon is induced by cellular exposure to arsenic and antimony oxyanions. The operon contains three cistrons that are homologous to the arsR , arsB, and arsC genes of plasmid-borne ars operons, coding for an arsenite/antimonite-inducible repressor, an inner membrane arsenite transporter, and an arsenate reductase, respectively. The E. coli chromosomal ars operon is functional in protection against arsenic toxicity, as mutants of this operon are hypersensitive to arsenic. To elucidate regulation of ars operon expression, two luciferase gene fusions, arsR::luxAB and arsB::luxAB , were constructed and analysed. The E. coli chromosomal ars operon was demonstrated to be regulated by the trans -acting repressor, ArsR, in a manner similar to that of the plasmid R773 ars operon. The operon is transcribed as a single transcription unit, and regulated by arsenic mainly though not exclusively, at the mRNA level. The individual gene products of the operon were visualized in both in vivo and in vitro expression systems. The chromosomal ars operon is conserved in the chromosomes of a number of Gram-negative bacterial species.To monitor the toxicity and bioavailability of arsenic compounds, the potential of the E. coli arsB::luxAB fusion strain as a bacterial biosensor has been evaluated. This luciferase gene fusion strain was shown to selectively detect the presence of arsenic in a mixed wood preservative, chromated copper arsenate (CCA).
To further elucidate the evolutionary relationship of chromosomal ars operons between different bacterial species, a Pseudomonas aeruginosa PAO1 chromosomal ars operon homolog was cloned and found to confer resistance to arsenite and antimonite, and to a lesser extent, to arsenate, in an E. coli ars -- mutant strain. Three cistrons were identified that share homology with the arsR, arsB, and arsC genes of other known ars operons. Expression of the P. aeruginosa ars operon is induced by arsenite as shown by RNA dot blots. Homologous sequences of this operon, have also been detected in other strains and species of the genus Pseudomonas.
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Martin, Tania Marie. "Housing the Grey Nuns : power, religion and women in fin-de-siècle Montréal." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=23201.
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Nineteenth-century Montreal convents are complex, multi-functional buildings. As a form of collective housing, convents provided an alternative urban "space" for women, one in which they were able to realize themselves individually and collectively. This thesis explores the Mother House of the Grey Nuns, typical of Montreal's convents, as a purpose-built environment for women.The research involves the extensive use of a unique documentary legacy preserved in the archives of the Grey Nuns: the architectural drawings and written accounts of Soeur Saint-Jean-de-la-Croix (1854-1921), in addition to the religious community's annals and period photographs. These documents recorded how the nuns organized their own built environment and permit a reconstruction of the convent's spatial arrangements, one hundred years after the fact. Although this building is monumental and designed by prominent Montreal architect Victor Bourgeau, it is only from exploring the perspectives of the users that we can truly see how large institutions operated. The division of the plans, the massing of the convent and its siting, among other aspects, communicate the nuns' distinct way of life, one that questioned the traditional boundaries of public and private imposed by society in turn-of-the-century Montreal, albeit from a limited position.
The convent is situated within the larger context of nineteenth-century Montreal, especially its hospitals, schools, asylums, and homes. While it shared many of the distinctive architectural features that characterized these building types, the convent also differed from them significantly in its organization. This thesis is intended to enrich our understanding of convents, the place in history of religious communities and the development of women in Quebec.
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Lago, Gilson Benedito Ferreira. "O acesso à justiça no estado do Maranhão e a implementação dos recursos do fundo especial para reaparelhamento do judiciário: a visão dos juízes de 1º grau." reponame:Repositório Institucional do FGV, 2006. http://hdl.handle.net/10438/7789.
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The right to the assistance is subsidized by Federal Constitution of 1988 as a basic right of all the considered citizens’ hipossufficients. In face of this gratuitousness, basic right, is protected and made possible other bigger principles constitutional, as the equality between the citizens, has seen the social and economic inequality evidenced in the Brazilian society. Therefore, an instrument is essential that guarantees the access to the jurisdictional guardianship. Through research carried through with the magistrates of the sub-divisions of Maranhão State, all possess knowledge of the saving purpose for Special maintenance of Justice Machine (FERJ), only one small number of the state lawyers is unaware from the plan elaboration and execution of programs and projects for modernization and develop the judiciary services. Thus, the number of accumulated processes becomes voluminous, in face of insufficient number of state lawyers, beyond the extreme bureaucracy that make it difficult to course the actions. One concludes that, the maintenance of the Judiciary Power in the Maranhão State did not bring the waited improvements.
O direito à assistência está subsidiado pela Constituição Federal de 1988 como um direito fundamental de todos os cidadãos considerados hipossuficientes. Em face dessa gratuidade, direito fundamental, são protegidos e viabilizados outros princípios constitucionais maiores, como a igualdade entre os cidadãos, haja vista a desigualdade social e econômica evidenciadas na sociedade brasileira. Portanto, é imprescindível um instrumento que garanta o acesso à tutela jurisdicional. Através de pesquisa realizada com os magistrados das entrâncias do Estado do Maranhão, todos possuem conhecimento da finalidade do Fundo Especial para Reaparelhamento do Judiciário (FERJ), apenas um pequeno número dos juízes desconhecem o plano de elaboração e execução de programas e projetos para a modernização e o desenvolvimento dos serviços judiciários. Assim, torna-se grande o número de processos acumulados, em face do número insuficiente de juízes, além da burocracia excessiva que dificultam o andamento das ações. Conclui-se que, a reestruturação do Poder Judiciário no Maranhão não trouxe as melhorias esperadas.
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Sebastiani, Giovanna. "Genetic and functional dissection of resistance to gram-negative infection in wild-derived mice." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=37833.
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Infectious diseases continue to be one of the leading causes of morbidity and mortality in the world. Infection of mice with Salmonella typhimurium causes a systemic disease reminiscent of human typhoid fever and constitutes one of the best-described models of infectious disease.We show that wild-derived Mus musculus molossinus (MOLF/Ei) mice are extremely susceptible to infection with S. typhimurium, despite resistance alleles at known Salmonella-susceptibility loci. To identify the genes responsible for the innate susceptibility of MOLF/Ei mice, we performed a genome-wide scan using a panel of (C57BL/6J x MOLF/Ei)F2 mice. Salmonella-resistance was linked to Nramp1 with a LOD score of 18.8 and to mouse chromosome 11 with peak LOD score of 7.0 at D11Mit5. One recessive, susceptibility QTL (quantitative trait loci) was identified on distal chromosome 1 with a maximal LOD score of 4.8 at D1Mit100.
In parallel, we undertook a functional dissection of the response of MOLF/Ei mice to infection with S. typhimurium. Kinetics of bacterial proliferation within the reticuloendothelial organs and histological evaluation of tissue sections suggest that MOLF/Ei mice do not succumb to infection following an overwhelming bacterial growth or massive tissue necrosis. We also demonstrate that, in spite of a normal response to Lipopolysaccharide and high expression of IL-1alpha and IL-1beta mRNA during infection, MOLF/Ei do not upregulate Nos2 mRNA expression and have a reduced capacity to release nitrite in vitro.
We examined the candidacy of several genes located within the chromosomal interval defined by our genetic analysis and thought to be involved in resistance to Salmonella infection. The newly described role of Toll-like receptors in innate immunity and the location of human TLR5 in a region homologous to the interval containing the mouse chromosome 1 Salmonella-susceptibility QTL prompted us to clone mouse Tlr5. Mouse Tlr5 mRNA encodes for an 859 amino acid protein predominantly expressed in the liver. As expected, Tlr5 maps to the distal chromosome 1. The decreased expression of Tlr5 mRNA in the liver of susceptible MOLF/Ei mice, as compared to other strains, suggests the possibility that Tlr5 may play a role in host response to Gram-negative infection in wild-derived mice.
We examined four candidate genes (Il12b, Csfgm, Nos2 and Mpo) within the Salmonella-resistance QTL on mouse chromosome 11. Although sequence analysis and mRNA expression studies reveal differences between the MOLF/Ei and C57BL/6J alleles, no definite conclusions can be drawn as to the roles of these genes in S. typhimurium infection. We created a series of B6.MOLF-Nramp1Gly169/chr11 congenic strains that collectively overlap the entire chromosome 11 QTL to define more precisely the chromosomal interval involved and, ultimately, to identify the causative gene(s). Preliminary testing of these strains confirms the presence of the MOLF/Ei-resistance locus and allows us to exclude the genomic area encompassing D11Mit84 and D11Mit141 from the QTL interval, thus eliminating Il12b as a candidate gene. Further characterisation of these strains will help elucidate which of the candidate genes on chromosome 11 confers resistance to infection with S. typhimurium.
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Costa, ?ngelo Gustavo Mendes. "Unidade de ensino potencialmente significativa (UEPS) como possibilidade para o ensino de fun??o polinomial do 1? grau: uma experi?ncia no ensino m?dio." PROGRAMA DE P?S-GRADUA??O EM ENSINO DE CI?NCIAS NATURAIS E MATEM?TICA, 2015. https://repositorio.ufrn.br/jspui/handle/123456789/22470.
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O presente trabalho discute aspectos relacionados a Teoria da Aprendizagem Significativa (TAS) aplicada ao ensino e aprendizagem de Fun??o Polinomial do 1? Grau. Para tanto objetivamos desenvolver uma Unidade de Ensino Potencialmente Significativa (UEPS), que proporcionasse sentido e significado no ensino e aprendizagem de Fun??o numa turma do 1? ano do ensino m?dio noturno. De in?cio fizemos um levantamento dos conhecimentos pr?vios que os alunos tinham sobre Fun??o, e, com base nos resultados obtidos elaboramos e aplicamos uma sequ?ncia de atividades que visavam apresentar e discutir os elementos que compunham uma Fun??o Polinomial do 1? Grau, bem como a rela??o existente entre tais elementos. Todos esses passos culminaram no nosso produto educacional que foi a elabora??o e aplica??o de uma UEPS. Ap?s a aplica??o do nosso produto percebemos uma melhora acentuada na compreens?o e manipula??o alg?brica e aritm?tica de uma Fun??o Polinomial do 1? Grau por parte dos alunos; ensejando a viabilidade em pautar o processo de ensino e aprendizagem numa forma de aprender que seja significativa.
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Valette, Jean-René. "La pensée du Graal : fiction littéraire et théologie : (XIIe - XIIIe siècle) /." Paris : Champion, 2008. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016386743&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA.
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Ekins, Andrew John. "Iron acquisition by Histophilus ovis." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=38481.
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Five strains (9L, 642A, 714, 5688T and 3384Y) of Histophilus ovis were investigated with respect to iron acquisition. All strains used ovine, bovine and goat, but not porcine or human, transferrins (Tfs) as iron sources for growth. In solid phase binding assays, total membranes from only two (9L and 642A) of the five strains, grown under iron-restricted conditions, were able to bind Tfs (ovine, bovine and goat, but not porcine or human). However, when the organisms were grown under iron-restricted conditions in the presence of bovine Tf, total membranes from all strains exhibited Tf binding (as above); competition experiments demonstrated that all three Tfs (ovine, bovine and goat) were bound by the same receptor(s). An affinity isolation procedure allowed the isolation of two putative Tf-binding polypeptides (78 and 66 kDa) from total membranes of strains 9L and 642A grown under iron-restricted conditions, and from membranes of all strains if the growth medium also contained Tf. A gene encoding a Pasteurella multocida TbpA homologue was shown to be present in each of two representative strains (9L and 3384Y); these genes were sequenced and determined to be the structural genes encoding the 78-kDa Tf-binding polypeptides. The identification of a fur homologue and a Fur box within the promoter region of tbpA in both strains indicated that Fur (and iron) is responsible for the iron-repressible nature of Tf-binding activity. Although tbpA transcripts were detected by reverse transcription (RT)-PCR with RNA isolated from strains 9L and 3384Y grown under iron-restricted conditions, with strain 3384Y, and depending on the primer pair, tbpA transcripts were detected by RT-PCR predominantly when the RNA was isolated from cells grown under conditions of iron-restriction in the presence of Tf. The presence of an additional G in the tbpA gene of strain 3384Y grown under iron-replete conditions, compared to organisms grown under iron-restricted conditions plus bovine Tf, is
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Grougiou, Vassiliki Elias. "The grey market and the service encounter : an investigation of satisfiers, dissatisfiers and complaining behaviour." Thesis, University of Strathclyde, 2008. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21944.
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The general aim of the research is to explore the factors that are salient to senior customers' evaluations of service encounters and the effect that these factors might have on senior customers' behavioural reactions and future intentions. This general aim is further analysed into the following research objectives: 1) to explore senior customers' key satisfiers and dissatisfiers with service encounters, 2) to explore the attitudes of senior customers towards the making of complaints about unsatisfactory service encounters, and 3) to explore the factors that influence senior customers' complaining behaviour responses to unsatisfactory service encounters. Taking an interpretative research position, the views of sixty senior customers are sought through the use of in-depth interviews and projective techniques. The selection of the interviewees is the result of heterogeneity and criterion purposive sampling. The analysis of the data for this study is iterative and follows the paths of i) analysis on site, ii) running the data open, iii) focusing the analysis, and iv) deepening the analysis. Analysis and interpretation of this data suggests that a) the majority of the interviewees tend to base their evaluation of their overall service encounter on affective rather than on cognitive issues, b) psychological and emotional limitations appear to be better indicators compared to biological ones of the majority of the interviewed seniors' needs and wants in service provision, and c) interviewees' complaining attitude and behaviour often seem to be mainly driven by their image management. This study illuminates senior customers' needs and wants in the service encounter and provides insights about their behavioural responses when faced with a service failure.
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Quinteira, Sandra Maria Basílio. "Eco-epidemiologia de bacilos de Gram negativo produtores de carbapenemases com impacto clínico." Tese, Porto : [Edição do Autor], 2005. http://catalogo.up.pt/F?func=find-b&local_base=UPB01&find_code=SYS&request=000097253.
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Jain, Sumeet. "From negotiation to accommodation : cultural relevance in the Asha Gram Mental Health Program, Barwani district, India." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=78184.
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This thesis analyzes the degree of cultural relevance in the Asha Gram Mental Health Program in Barwani, India. The focus is on the role of community mental health workers as bridges between a professional culture of psychiatry and the local cultural understandings of mental health. Processes of cultural interaction are analyzed on a continuum from negotiation, defined as interaction without fundamental cultural change, to accommodation, defined as interaction with cultural change. Accommodation at the level of the vision of mental health disorders was limited while there was an active negotiation that resulted in some transformation of the social vision. Negotiation with communities at the level of relationships underpinned this transformation and contributed to a social accommodation with local forms of relationships. Although, professional and class power were important obstacles to achieving cultural relevance, the Program also demonstrates the necessity to subvert this power in order to create social change.
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Dittmann, Lars. "Der angemessene Grad an Visibilität in Logistik-Netzwerken : die Auswirkungen von RFID /." Wiesbaden : Dt. Univ.-Verl, 2006. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=014904470&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
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Knoll, Tilmann. "Self-Awareness von Führungskräften: Messung und individuelle Unterschiede in einem 360-Grad-Feedback /." Göttingen : Cuvillier, 2005. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015203101&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
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Hofer, Franz. "The improvement of technology transfer : an analysis of practices between Graz University of Technology and Styrian companies /." Wiesbaden : Dt. Univ.-Verl, 2007. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016085504&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA.
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Gardiner, Karen J. "Some aspects of the reproductive endocronology of harbour seals (Phoca vitulina) and grey seals (Halichoerus grypus)." Thesis, University of Aberdeen, 1994. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU068319.
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This study describes annual hormone cycles in wild and captive harbour seals, considers hormonal changes in wild grey seals during their lactation period, investigates the changing responsiveness of the pituitary-gonad axis throughout the year to stimulation with small single doses of gonadotrophin releasing hormone (GnRH) and addresses the possible influence of the experimental techniques upon the results using plasma cortisol concentrations as an index of stress. In captive harbour seals, LH concentrations through the year were significantly different only in the pregnant female. Plasma FSH concentrations were significantly different throughout the year only in the two non-pregnant females, being highest during delayed implantation. Plasma progesterone concentrations were significantly different throughout the year in both the pregnant and non-pregnant females. In wild harbour seals, plasma FSH concentrations were not significantly different throughout the year in the adult females but were significantly different in the immature females between stage 1 and 4 (post-partum oestrus and late gestation for the mature females). Plasma progesterone concentrations were significantly different throughout the year only in the adult females. In wild male harbour seals plasma testosterone concentrations were significantly different in adults between the pre-breeding and breeding season, being highest in the pre-breeding season. In wild lactating grey seals, plasma progesterone and FSH concentrations were low throughout most of lactation but increased late on. Plasma prolactin concentrations were highest during mid-lactation decreasing at the time when behavioural oestrus was observed. In all captive harbour seals and wild and captive grey seals an increase in plasma LH concentration was measured following GnRH administration returning to pre-GnRH concentrations within ninety minutes. In lactating female grey seals the magnitude of the LH response was smaller than in the other animals but was more prolonged.
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Tremblay, Yannick. "Acquisition of haemoglobin-bound iron by Histophilus somni." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=82441.
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Ovine (strains 9L and 3384Y) and bovine (strains 649, 2336 and 8025) isolates of Histophilus somni were investigated for their ability to acquire iron from haemoglobin (Hb). Bovine isolates were capable of utilizing bovine, but not ovine, porcine or human Hb as a source of iron. Ovine isolates could not obtain iron from Hb. Bovine isolates bound bovine, ovine, and human Hbs by means of the same iron-repressible receptor(s) and produced a ~120-kDa iron-repressible, outer membrane protein. Using PCR approaches, an iron-regulated operon containing hugX and hugZ homologues and a gene (hgbA) that encodes a TonB-dependent, Hb-binding proteins were identified in strains 649, 9L and 3384Y. In strains 9L and 3384Y, HgbA is truncated offering a possible explanation for their lack of utilization of Hb as an iron source. In strains 2336 and 8025, expression of HgbA was also subject to a form of phase variation.
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Yam, Karen. "The innate inflammatory effects of the Gram-positive bacterium «Lactococcus lactis» and its application as live vaccines against leishmaniasis." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=92152.
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Lactococcus lactis is a non-pathogenic and non-colonizing Gram-positive bacterium commonly used in the dairy industry. Given its probiotic potential, the first objective of this thesis was to investigate the effects of L. lactis on the immune system. We compared the innate inflammatory effects of L. lactis with two Gram-negative bacterial strains: Escherichia coli, and attenuated Salmonella typhi, a widely used live bacterial vaccine. The gene expression profiles of chemokines induced by the three bacteria were examined in macrophages in vitro and in cells recruited into murine air-pouches in vivo. Also, we studied the effect of co-incubating bacteria with dendritic cells generated from mice bone marrow. We demonstrated that L. lactis may display inherent adjuvant activity since this bacterium exhibits innate inflammatory effects. These results support the use of L. lactis as a live bacterial vector to deliver biological molecules, such as vaccine antigens. The second objective of this thesis was to investigate the potential of using L. lactis to generate live vaccines against leishmaniasis. The parasite Leishmania affects a considerable number of individuals worldwide and is considered a neglected tropical disease by the World Health Organization. Although there are highly promising vaccine antigens and much ongoing research, there is still no vaccine available for clinical use against leishmaniasis. We engineered strains of L. lactis to express two known protective antigens against Leishmania: A2 and LACK. Both antigens were engineered for expression at differential subcellular localizations of L. lactis: in the cytoplasm, secreted into the media, or anchored to the cell-wall. Subcutaneous immunizations with live L. lactis vaccine strains were able to induce antigen-specific immune responses in mice. Moreover, we demonstrated that immunization with live L. lactis expressing A2 in the cytoplasm could protect mice against visceral Leishmania donovani infection,Lactococcus lactis est une bactérie Gram-positive non-pathogène et non-colonisante fréquemment utilisée dans l'industrie laitière. Etant donné ses caractéristiques probiotiques, notre premier objectif fut d'étudier les effets de L. lactis sur le système immunitaire. Nous avons comparé les effets inflammatoires innés de L. lactis avec deux souches de bactéries attenuées Gram-négatives: Escherichia coli et Salmonella typhi, cette dernière étant déjà largement utilisée dans la formulation de vaccins vivants bactériens. Nous avons étudié le profil d'expression des chémokines induites par les trois souches bactériennes in vitro à partir d'une lignée de cellules de macrophages et in vivo au niveau des cellules recrutées dans un modèle murin de poches d'airs. Nous avons aussi étudié les effets de co-incuber ces bactéries avec des cellules dendritiques murines isolées de la moelle osseuse. Nous avons démontré que L. lactis peut afficher des caractéristiques inhérentes d'adjuvant parce qu'elle induit des effets inflammatoires innés. Cette raison valide l'utilisation de L. lactis comme vecteur bactérien vivant pour livrer des molécules biologiques, comme des antigènes pour la vaccination. Notre deuxième objectif a été d'étudier le potentiel d'utiliser L. lactis pour créer des vaccins vivants contre les leishmanioses. Les parasites Leishmania affectent un nombre considérable d'individus dans le monde. Les leishmanioses sont considérées comme des maladies tropicales négligées par l'Organisation Mondiale de la Santé. Malgré des efforts de recherches soutenus ainsi que la caractérisation d'antigènes hautement prometteurs pour la vaccination, il n'existe encore aucun vaccin pour utilisation clinique contre les leishmanioses. Un vaccin efficace contre les différentes formes de leishmanioses serait donc hautement bénéfique. Nous avons construit des souches de L. lactis qui expriment deux antigènes protecteurs de Leishmania
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Krapf, Erwin. "Parallelimporte von Arzneimitteln und europäisches Kartellrecht : eine Untersuchung von Vertriebssystemen zur Verhinderung des Parallelhandels /." Aachen : Shaker, 2006. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015455947&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
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Bertolatti, Dean. "Antimicrobial resistance in gram-positive cocci isolated from poultry in Western Australia : an assessment of poultry meat as a vehicle for the transmission of resistant strains via the food chain." Curtin University of Technology, School of Public Health, 2002. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=12997.
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The aim of this study was to examine whether Gram-positive cocci isolated from processed poultry in Western Australia provided a potential risk for the transfer of antimicrobial-resistant organisms to humans via commercially prepared ready-to-eat chicken. Research in this study was conducted in three phases: the characterisation of Gram-positive cocci isolated from poultry, an assessment of the isolates' thermal tolerance and the development of a Hazard Analysis Critical Control Points (HACCP) based food-safety program. In the first phase of the study, three specific objectives were investigated. The first determined the presence of Gram-positive cocci on poultry and on processing equipment from poultry-processing plants. The findings confirm the presence of staphylococci and enterococci on incoming live and slaughtered birds and processed carcasses. The data also indicate that carcasses probably become cross-contaminated during processing, when these bacteria are present on the incoming live birds and equipment. The second objective was to characterise staphylococcal isolates by antimicrobial susceptibility testing, and chromosomal and plasmid DNA analysis. The susceptibility of isolates to antimicrobial agents was tested by the disk diffusion method according to the NCCLS (National Committee for Clinical Laboratory Standards) guidelines. Isolates were typed by contour-clamped homogeneous electric field (CHEF) gel electrophoresis of SmaI digested chromosomal DNA, and plasmids were isolated by the cetyltrimethylammonium bromide (CTAB) method. Approximately 37% of Staphylococcus aureus and 16% of coagulase-negative staphylococcal (CNS) isolates were resistant to six or more of the antimicrobial agents tested. Many isolates exhibited resistance to antibiotics that are commonly used in human medicine and registered for veterinary use in Australia.Among the S. aureus isolates there were twenty-four epidemiologically unrelated SmaI CHEF groups. All staphylococcal isolates, except three CNS, were found to harbour from one to seven plasmids. Some staphylococcal isolates with epidemiologically related CHEF patterns had similar plasmid profiles and resistance patterns. The third objective was to determine the antimicrobial susceptibility of enterococci isolates to the glycopeptide antibiotics. The isolation of two vancomycin-resistant E. faecalis isolates is the first report of VRE outside the health-care setting in Western Australia. Additionally the detection of the vanA gene in an E. gallinarum isolate, a motile enterococcus, has potentially important implications for infection control practices in hospitals. In the second phase of the study, three specific objectives were established to investigate the practical implications of these findings for the chicken industry. The first objective of this phase of the study was to determine the thermal tolerance (D and Z-values) of antimicrobial-resistant, Gram-positive cocci in ground chicken meat. The results indicate that these isolates do not exhibit enhanced thermal-resistance characteristics compared to antimicrobial-susceptible bacteria. The second objective established the internal time-temperature profiles for cooking commercially prepared chicken and estimated the process lethality (F-values).
From three cooking trials, it was confirmed that the internal temperature of at least 70°C was achieved for at least thirty-eight minutes. The third objective of this phase assessed the effectiveness of the thermal process in reducing the risk of the transfer of antimicrobial-resistant cocci via the food chain. The data confirm that the lethal effect (F-values) of the thermal process destroyed these antimicrobial-resistant cocci in commercially prepared ready-to-eat chicken. In the third phase of the study, the data obtained in the earlier parts of the study was incorporated into a model food-safety program for a fast-food chicken chain. The model was based upon the internationally accepted HACCP system, adopted by the Codex Alimentarius Commission. Mindful that the thermal-process step represents only one critical control point in the safe preparation of chicken, this preventative approach ensures that all hazards are controlled at every other step of the process. The data suggest that antimicrobial-resistant, Gram-positive cocci will be present on some ready-to-cook poultry meat processed in Western Australia. This creates opportunities for the potential spread of resistant strains or resistance genes to humans via the food chain. The information from this study will be useful in providing background data and direction for future planning in preventing antimicrobial-resistant bacteria from poultry meat being transmitted through the food chain. The full implementation of the HACCP program would offer substantial benefits and protection to consumers.
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Paschoal, Paulo Zanotto de. "An??lise do grau de prefer??ncia das maiores empresas brasileiras entre os sistemas : balanced scorecard X sistema de medi????o de desempenho da Funda????o Para o Pr??mio Nacional da Qualidade - FPNQ." FECAP - Faculdade Escola de Com??rcio ??lvares Penteado, 2003. http://132.0.0.61:8080/tede/handle/tede/620.
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Previous issue date: 2003-10-24This research paper attempted to identify the representativity of the use of management systems based on indicators of performance with the objective of verifying the preference of major Brazilian enterprises in the use of such systems. In order to meet this objective the following concepts of management systems based on indicators of performance were used: The Balanced Scorecard (BSC) and the system proposed by Funda????o para Pr??mio Nacional da Qualidade (FPNQ). A field research of the survey type was carried out and the information obtained was treated in a quantitative as well as qualitative form The sample was delimited for the 300 major private enterprises as classified by the Exame magazine July of 2002 issue, where the Southeast region of Brazil was selected for representing 80% of the invoices concentration, compared to the other geographic regions of Brazil. The analysis of data verified that among the users of Management Systems based in Indicators of Performance (SGBID), there is preference for the use of System Measuring Performance (FPNQ) over the (BSC), and it was observed in both systems a stressed representation of users of (SGBID) in enterprises of industrial order. The analysis of data verified also aspects related to the preference for the use of a specific system of strategy management as origin of stock capital which showed greater representativity in enterprises with its stock capital of foreign origin which shows a cultural aspect that is reinforced by the fact that 50% of the respondents were unknowing of the (SGBID).
O presente trabalho buscou identificar a representatividade do uso de sistema de gest??o baseado em indicadores de desempenho, com intuito de verificar qual a prefer??ncia das maiores empresas brasileiras na utiliza????o de tais sistemas. Para atender esse objetivo utilizou-se o conceito de sistemas de gest??o baseado em indicadores de desempenho: Balanced Scorecard - (BSC) e o sistema proposto pela Funda????o para o Pr??mio Nacional da Qualidade - (FPNQ). Foi realizada uma pesquisa de campo do tipo Survey e as informa????es obtidas foram tratadas de forma quantitativa e qualitativa. A amostra foi delimitada para as 300 maiores empresas do setor privado, segundo a classifica????o da revista Exame edi????o de julho de 2002, onde foi selecionada a regi??o sudeste por representar 80% da concentra????o do faturamento em rela????o ??s demais regi??es do Brasil. A an??lise dos dados permitiu verificar que, entre os usu??rios de Sistemas de Gest??o Baseada em Indicadores de Desempenho - (SGBID), existe uma prefer??ncia pelo uso do Sistema de Medi????o de Desempenho (FPNQ) em rela????o ao (BSC), sendo que houve em ambos os sistemas uma representa????o acentuada de usu??rios dos (SGBID) pelas empresas de atividade industrial. A an??lise dos dados tamb??m verificou aspectos relacionados ?? prefer??ncia de utiliza????o de determinado sistema na gest??o estrat??gica, como origem do capital acion??rio, que apresentou uma maior representatividade de empresas com o seu capital acion??rio de origem estrangeira, que denota um aspecto cultural. Que tamb??m ?? refor??ado pelo fato de 50% dos respondentes desconhecerem os (SGBID).
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Derakhshan, Mishkin. "Using magnetic resonance imaging for the in vivo detection and characterization of cerebral grey matter pathology in patients with multiple sclerosis." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116946.
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Magnetic resonance imaging has become an invaluable tool in clinical neurology because of its ability to provide excellent contrast between different soft tissues of the brain, including pathologically altered tissues. Image processing methods can be used to further the detection and quantification of such tissues, as has been the case for the well-studied white matter (WM) lesions in the brains of patients with multiple sclerosis (MS). Considered an immune-mediated disease of the central nervous system, MS has long been believed to be a disease of the WM, though recent studies have shifted the focus to the pathologically altered grey matter (GM) tissue, which is difficult to visualize in vivo. As the appreciation grows for cortical GM pathology in patients with MS, so does the need for imaging methods that capture said pathology and for understanding the relationship of those methods to the clinical outcome of the patient. Hence, the main objective of this thesis was to evaluate and develop image processing methods for the in vivo quantification of GM pathology in patients with MS. We reveal the strengths and weaknesses of the currently available techniques for measuring GM pathology, highlighting the need for separate cortical and deep GM methodologies. We also, introduced a novel surface-based technique involving magnetization transfer ratio (MTR) images for imaging putative areas of subpial demyelination, the most common form of cortical lesion seen on postmortem analysis that has yet to be captured via in vivo imaging techniques. Finally, we showed that, of the imaging metrics available for measuring cortical pathology, widespread cortical damage detected with surface-based measures of MTR have the strongest relationship to cognitive performance in cognitively impaired patients with MS. Importantly, all cross-sectional studies were performed using images typically obtained in the clinical setting and at the accessible field strengths of 1.5 T and 3 T, giving the work instant clinical feasibility and relevance.L'imagerie par résonance magnétique est un outil précieux en neurologie grâce à sa capacité à fournir un excellent contraste entre différents tissus du cerveau, y compris les tissus altérés pathologiquement. Les méthodes de traitement d'image peuvent être utilisées pour favoriser la détection et la quantification de ces tissus, comme dans le cas des lésions de la substance blanche (SB) du cerveau des patients atteints de sclérose en plaques (SEP). Considérée comme une maladie auto-immune du système nerveux central, la SEP a longtemps été étudiée comme une maladie de la substance blanche. Des études récentes ont déplacé l'attention vers les pathologies de matière grise (SG) du tissu qui sont difficiles à visualiser in vivo. L'appréciation se développe pour la pathologie de la SG corticale chez les patients atteints de SEP, tout comme le besoin de méthodes d'imagerie qui capturent ladite pathologie et la compréhension de la relation de ces méthodes à l'évolution clinique du patient. Par conséquent, l’objectif principal de cette thèse est l'évaluation et le développement de méthodes de traitement d'image pour la quantification in vivo de la pathologie de SG chez les patients avec la SEP. Nous révélons les forces et les faiblesses des techniques disponibles pour mesurer la pathologie de SG, soulignant la nécessité de séparer les méthodes pour le SG corticale et profonde. Ensuite, on présente une nouvelle technique de surface impliquant des images de rapport de transfert de magnétisation (MTR) pour étudier les zones possibles de démyélinisation sous-pie-mère, la forme la plus commune de lésion corticale observée en analyse post-mortem qui n'ait pas encore été vue par l'intermédiaire d'imagerie in vivo. Enfin, nous montrons que, parmis les indicateurs disponibles pour mesurer pathologie corticale en imagerie, les lésions corticales détectées à l'aire de mesures de MTR sur des surfaces ont la corrélation la plus forte avec la performance cognitive chez des patients atteints de SEP avec des facultés cognitives affaiblies. Fait important, toutes les études transversales ont été réalisées à partir d'images obtenues typiquement en milieu clinique et à des niveaux de champs de 1,5 T et 3 T, conférant à cet ouvrage faisabilité et pertinence clinique.
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Skarka, Johannes. "Ökobilanzielle Abschätzung der Bereitstellung von Bioenergie : Strom und Wärme aus Gras-, Maissilage, Heu und Pappelhackschnitzeln /." Karlsruhe : Institut für Geographie und Geoökologie, 2008. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016530889&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
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Ludong, Daniel Peter M. "Effects of irrigation rate on the growth, yield, nutritive value, and water use efficiency of Carrot (Daucus carota) and Broccoli (Brasiola oleracea)." Curtin University of Technology, Muresk Institute of Agriculture, Faculty of Science and Engineering, 2008. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=119758.
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The effects of differential irrigation treatments on the water use of broccoli (c.v. Indurance) and carrots (c.v. Stefano) were studied in the rainy, winter season from July to September 2006 and in the dry, summer period from November 2006 to March 2007, respectively. Broccoli and carrots are produced on the Swan Coastal Plain region on Grey Phase Karrakatta Sand. Such soils generally have water holding capacities as low as 10 to 13%. This soil is typical to the Swan Coastal Plain and requires irrigation to be applied at rates of up to 150% of class A pan evaporation (Epan) to optimise growth and quality.High spatial uniformity (an average of 90%) of water distribution (DU) was achieved with the sprinkler irrigation system. The average irrigation water use efficiencies (Eu) in both the experiments were relatively high, at 78% and 95% in broccoli and carrot trials, respectively. The numerous rainy days during the winter season affected the results of water application efficiencies (Ea) of the broccoli experiment, which ranged from 35% to 43%. This contrasted with the carrot experiment where the water application efficiencies (Ea) of the 100% Epan and Crop Factor (CF) treatments were 81% and 78%, respectively. For the carrot experiment the water application efficiencies for the 100% Epan and crop factor treatments were 14% higher than the 150% Epan treatment. These results indicate that the sprinkler irrigation systems in both experiments showed good performance makes the system suitable for experimental purposes and also for vegetable production on soils of this nature.
Despite the differences in irrigation volume, soil water contents remained very high and did not differ among treatments in both the experiments. The differential soil water stress index (DSWSI) for the 100% Epan (T1) and variable water replacement (VR) (TVR) treatments ranged from 0.74 to 1.71 for both broccoli and carrot trials. There were only small soil water tension differences among all the irrigation treatments and ranged from -2.4 kPa to -7.6 kPa, which was within the range between saturation and field capacity for sandy soil (0 to -10 kPa).
In the broccoli experiment, even though the 150% Epan (T2) irrigation treatment received 46% and 61% more irrigation than the 100% Epan (T1) and variable water replacement (TVR) irrigation treatments respectively, the treatments appeared to be largely negated by the high incidence of rainfall during the growing season. For example, the total depth of water application at 150% Epan was 13.9% and 17.2% greater than 100% Epan and TVR treatments respectively. As such the yield, biomass components and nutritional value (ascorbic acid and carotenoid content) did not vary among the treatments. However, irrigation was still required based on the set scheduling parameters and when considered in isolation of rainfall the irrigation crop water use efficiency (WUEi) on T1 and TVR treatments increased by 1.6-fold compared to T2 treatment.
For the carrot experiment the total depth of water application (rainfall and irrigation) for the 150% Epan treatment was 33% and 23% greater than at 100% Epan and Crop factor (CF) treatments, respectively. The yield (carrot roots) on a fresh weight basis (FW) for plants irrigated with the 150% of Epan and Crop factor (CF) treatments were 16% and 20% higher than the yield for plants irrigated with the 100% Epan treatment. Total (root and shoot) fresh weight of carrot plants irrigated For the carrot experiment the total depth of water application (rainfall and irrigation) for the 150% Epan treatment was 33% and 23% greater than at 100% Epan and Crop factor (CF) treatments, respectively. The yield (carrot roots) on a fresh weight basis (FW) for plants irrigated with the 150% of Epan and Crop factor (CF) treatments were 16% and 20% higher than the yield for plants irrigated with the 100% Epan treatment. Total (root and shoot) fresh weight of carrot plants irrigated with the CF treatment was 17% higher than the total fresh weight of plants irrigated with the 100% Epan treatment. However, there were no significant differences between irrigation treatments for root and total (root and shoot) mass on a dry weight basis and the ratio of carrot root to shoot, on a fresh and dry weight basis. The root lengths for plants grown with the CF and 150% Epan irrigation treatments averaged 30 cm, and were 14% larger than the root lengths for the 100% Epan treatment. The plant height for plants grown with the CF irrigation treatment was 6% higher than at the 100% Epan irrigation treatment and leaf length at the CF irrigation treatment was 12% greater than at the 150% Epan irrigation treatment. The root diameter and leaf width of carrots were not significantly different for all treatments. There were no significant differences in ascorbic acid and total carotenoid content of carrot roots among the three irrigation treatments. The average values of antioxidant content from diphenylpicrylhydrazyl (DPPH) scavenging, ARP (anti radical power) and total trolox equivalent antioxidant capacity were 44.83%, 0.8789 and 1.056μmol TE/g, respectively. The reduction of the irrigation level treatment from the 150% Epan water replacement to the 100% Epan water replacement increased the percentage of the DPPH scavenging by 1.55%, and total antioxidant capacity (AOC) and ARP activities by 4.19%.
On a dry weight basis, the crop water use efficiencies (WUE) (irrigation plus rain water) of carrot plants irrigated with the 100% Epan and CF treatments, were the same (0.013 g/mm). However, these were 30% greater than the WUE values of carrots irrigated with the 150% Epan treatment. On a fresh weight basis, the WUE of carrot plants irrigated with the 100% Epan and CF (0.120 and 0.132 g/mm) treatments were 14% and 26% greater than the WUE of carrot plants irrigated with the 150% Epan treatment, respectively.
An example of the diurnal trends of the carrot’s physiological responses to the irrigation treatments showed that on average, the rate of photosynthesis, stomatal conductance and intercellular CO2 for carrot plants grown with the 150% Epan treatment was higher than the rate of photosynthesis, stomatal conductance and intercellular CO2 at both the 100% Epan and CF treatments. However, not all the physiology measurements showed a significant difference among all the treatments. The variation in the physiological measurements was predominantly influenced by the change of temperature during the diurnal hours.
This study has proven the hypothesis that, on a free draining sandy soil, the irrigation treatments did not affect the growth and yield. However, there was a potential to reduce irrigation volumes from standard industry levels to maximise the WUE without decreasing the yield and crop quality, especially for broccoli and carrot, in Western Australia.
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Schotte, Manuela. "Christen, Heiden und der Gral : die Heidendarstellung als Instrument der Rezeptionslenkung in den mittelhochdeutschen Gralromanen des 13. Jahrhunderts /." Frankfurt am Main [u.a.] : Lang, 2008. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016977494&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
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Plank, Georg. "Was kommt nach Trient? : kirchliche Personalentwicklung nach dem II. Vatikanum /." Wien : Lit, 2005. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=013361931&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
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Dias, Maria de Fátima Pereira Batista. "Construção e validação de um inventário de competências : contributos para a definição de um perfil de competências do enfermeiro com o grau de licenciado." Tese, Porto : Edição do Autor, 2002. http://catalogo.up.pt/F?func=find-b&local_base=UPB01&find_code=SYS&request=000090187.
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Pöllabauer, Sonja. ""I don't understand your English, Miss." : Dolmetschen bei Asylanhörungen /." Tübingen : Narr, 2005. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=014739449&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA.
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Watzka, Carlos. "Arme, Kranke, Verrückte : Hospitäler und Krankenhäuser in der Steiermark vom 16. bis zum 18. Jahrhundert und ihre Bedeutung für den Umgang mit psychisch Kranken." Graz, 2007. http://bvbr.bib-bvb.de:8991/F?func=service&docl̲ibrary=BVB01&docn̲umber=015684514&linen̲umber=0001&funcc̲ode=DBR̲ECORDS&servicet̲ype=MEDIA.
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Jelsma, Johan. "A bed of ochre : mortuary practices and social structure of a maritime archaic Indian society at Port au Choix, Newfoundland /." Groningen : Rijksuniversiteit Groningen, 2000. http://dissertations.ub.rug.nl/faculties/arts/2000/j.jelsma/.
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Tseng, Chiang, and 曾強. "The Predictability of REIT Exchange-Traded Fund-A Comparison of Gray Prediction and the Neural Network." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/72407834923302864995.
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碩士中原大學
企業管理研究所
98
The REIT-ETF possesses the features of making profit on stock from capital gain and its dividens, as well as the passive management of ETF index. Further, it may spread risks more effectively than single REIT, and thus, it becomes the newest investing tool in the field of real estate. In August of 2007, the Subprime Mortgage Crisis happened in the USA and rolled up worldwide, affecting to the weak economic growth globally. Therefore, the credit markets shrank seriously back then, and the real estate market was in the front of this tide. Causing a bubbling trend. If the trends in house prices could be precisely estimated with early, detection of asset bubbles, thereby offering investors with crucial reference. This research uses the 21 REIT-ETFs among the USA, Canada, Europe, Asia and global countries, exaiming the effects of interest rate, dollar index, stock index, Put/Call ratio, fluctuation index, Commodity Research Bureau index (CRB) index and oil price of West Texas. etc. To ranking the the most crucial factor on the REIT-ETF by means of Gray Relation Analysis, the determining factors will be used to forecaste REIT-ETF, through the cross-match of Grey Prediction GM(1,N) and Artificial Neural Network System of Back-propagation Network. The study results show that the REIT-ETF is affected the most notably by stock indexes, oil price of West Texas, CRB index, Put/Call ratio. In relation to forecasting results, the Back-propagation Network is superior than GM (1,N) model in terms of smaller average Root Mean Square Error (RMSE). Among them, the best estimated performance is for XRE in Canada investment, representing that the forecast model established by stock indexes, oil price of West Texas, CRB index and Put/Call ratio has excellent predicting performance.
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Chu, Pei-Cheng, and 朱倍誠. "Taiwan Mutual Fund Performance Evaluation and The Relevant Economic Variables Forecast–Application of Grey System Theory." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/45864931902643354761.
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碩士樹德科技大學
經營管理研究所
99
Mutual funds is entrusted to professional financial institutions, diversified investment in the financial markets, giving investors the opportunity to pursue a stable return. Mutual funds in Taiwan is influenced by the Taiwan Weighted Index and its related impact of economic variables, and also affects the performance of fund performance. This study is discussed from 2009 to 2010 per quarter relationship between performance of the Taiwan stock funds and economic data. Republic of China Securities Investment Trust and Consulting Association announced the opening of Taiwan Equity Fund Performance of the top five of object-oriented. Because mutual funds are a wide range of investment, and the complex factors that affect the fund performance. In this research, the gray gray system theory for analysis associated with the gray prediction. By their correlation and prediction of the characteristics of the impact of Fund Performance discusses the relevant economic variables. And use of better forecasting model accuracy: GM (1,1) model, least squares, exponential smoothing method for prediction and validation,in order to achieve the combination of theory and realities. Expected to provide investors in mutual fund selection and portfolio strategy development when the objective basis. Studies have shown that the results of gray relational analysis is: HSBC successful fund performance associated with the highest foreign exchange reserves, CSC Grammy fund performance and Fubon high growth fund performance are associated with the highest import value, Prudential New Century fund associated with the highest exchange rate, WF WF associated with the highest export value. In the forecasting model, GM (1,1) model and least squares model are higher than the 80% average accuracy, and these models are also useful for the efficient prediction models.
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Yang, Hsiu-I., and 楊修懿. "An Application of the Grey System Theory on Mutual Fund Performance Evaluation and Net Asset Value Forecasting." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/32393195915641979981.
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碩士大葉大學
事業經營研究所
89
This study employs the grey relationship analysis of grey system theory to evaluate mutual fund performance, and the grey forecasting of grey system theory to predict net asset values. The sample includes 104 domestic open-ended stock funds. The time period spans from Feb. 4, 1999 to Dec. 27, 2000 with 510 daily net asset values for each fund. The main findings are as followings: 1.The overall performance of the mutual funds is superior to that of the market portfolio. 2.When investors evaluate mutual fund performance based on rate of return and risk, the most critical factor is the rate of return. 3.There is no significant difference between the performance of the four old investment companies and other mutual funds. 4.The “technological” stock funds might have better performance than the “special” stock funds. 5.To evaluate mutual fund performance by using grey relationship analysis, the investors can adjust the evaluation weights according to their needs and preferences for risk and rate of return. The investors can thus choose the right mutual funds to fit their own needs. 6.The average forecast error of the grey forecasting is smaller than 2%.
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Hsieh, Ho-Lin, and 謝和霖. "The Performance Evaluation in Taiwan Mutual Funds : The Application of Grey System Theory." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/13188714549194698869.
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碩士國立臺北商業技術學院
財務金融研究所
96
In this study, we examine the performances of Taiwnese-based mutual funds. We extend the international evidence on timing and selectivity skills of funds managers by appling the models of Treynor (1966) and Henriksson (1981) to 73 Taiwanese-based open-ended mutual funds investing in local equites from 2003 to 2007. In addition, this study applies the grey relational analysis to rank these funds and to evaluate factors that affect the funds’ performances. The result shows that Taiwanese fund managers do not exhibit the market timing and stock selection abilities, similar to the previous findings. Furthermore, we found that there is performance persistence according to the spearman rank relative test. Of all factors that affect the funds’ performances, we show that the most important factor is the long-run sharp ratio, while the turnover and investment ratio seem to be relatively trivial. The result provides further insights in fund’s performance evaluation.
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Li, Tang Yi, and 唐宜立. "Momentum Investment Strategies and Performance Persistence of Mutual Funds Based on Grey Theory." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/75209315682671072208.
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碩士銘傳大學
金融研究所
87
Abstract This study explores the momentum investment strategies and performance persistence of Taiwan open-end mutual funds based on Grey Theory from January 1996 to December 1998. Using the Entropy method to estimate the weights of the attributes affect the performance of the mutual funds. Our results show: first, the grey relational grade has the performance persistence during our study period. However, the traditional method (Sharp, Treynor and Jensen) don''t have the result. Second, whenever the market is, the earlier performance ranking results by the traditional methods can''t be a investment decision. However, the earlier ranking result（J=3）and the next period （K=1）have the positive investment persistence by grey relational grade. Third, buying the winner is better than the loser during our study period. The last, we demonstrate that at the same time the "momentum effect" of the stocks has no relation with the "momentum effect" of the mutual funds in Taiwan. This result is opposite with Wermer(1999).