Log in

Relevant bibliographies by topics / Grignard reagents / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Grignard reagents.

Dissertations / Theses on the topic 'Grignard reagents'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Grignard reagents.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Oswald, John Francis. "The mechanism of Grignard reagent formation." Thesis, Georgia Institute of Technology, 1987. http://hdl.handle.net/1853/27140.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Genders, J. D. "The preparation of organolithium and Grignard reagents by electrolysis." Thesis, University of Southampton, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356524.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Sapountzis, Ioannis. "New Functionalized Grignard Reagents and their Applications in Amination Reactions." Diss., lmu, 2004. http://nbn-resolving.de/urn:nbn:de:bvb:19-24940.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Bell, Amber. "A Modified Route to Cyclopenta[C]Thophenes Via Grignard Reagents." TopSCHOLAR®, 2007. http://digitalcommons.wku.edu/theses/963.

Full text

Abstract:

The synthesis of cyclopenta[c]thiophenes is sparsely found in literature due to the several difficulties of their synthesis. Our research has shown that we could modify a previously known route to 1,3-disubstituted cyclopenta[c]thiophenes using traditional Grignard chemistry. Along the way we discovered the synthetic route we were using had several omissions. Therefore, we were required to completely fill in missing experimentals in order to obtain each cyclopenta[c]thiophene intermediate, in high purity and good yield. In addition, we were able to fully characterize via NMR, our intermediates

APA, Harvard, Vancouver, ISO, and other styles

5

Tang, Xiaoping. "New Methodologies in Organic Synthesis using Grignard and Organoaluminium Reagents." Thesis, University of Nottingham, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.523491.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Geurts, Koen. "Copper-catalysed asymmetric carbon-carbon bond formation using Grignard reagents." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 2008.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

7

Lin, Wenwei. "Preparation of Polyfunctionalized Grignard Reagents and their Application in Aryne Chemistry." Diss., [S.l.] : [s.n.], 2006. http://edoc.ub.uni-muenchen.de/archive/00006045.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Fox, David J. "Asymmetric addition reactions." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343039.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Ikeda, Daiji. "Studies on reactions of alkyl Grignard reagents under iron-copper cooperative catalysis." 京都大学 (Kyoto University), 2009. http://hdl.handle.net/2433/126556.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Reid, Gary Patrick. "Diastereoselective conjugate additions of Grignard reagents to homochiral fumarates derived from Oppolzer's sultam." Thesis, University of Glasgow, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.400696.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Patwardhan, Neeraj Narendra. "Study of Synthesis, Reactions and Enantiomerization of C_α-Chiral Grignard Reagents". Diss., Virginia Tech, 2012. http://hdl.handle.net/10919/37814.

Full text

Abstract:

The development of chiral organometallics for asymmetric synthesis is a topic of significant research in the recent past. The most studied in this class are the chiral organolithium reagents with many reported examples. The primary focus of our research is the development of C<sub>α</sub>-chiral Grignard reagents, where the metal bearing α-carbon is the sole source of chirality. Examples of such Grignard reagents are rare owing to the problems associated with their synthesis, and their low configurational stability. We have studied these problems in three different modules of this project.

APA, Harvard, Vancouver, ISO, and other styles

12

Gillmore, Jason G. Jr. "Evaluation of 1,1-Dimethyl-5,7-Di-T-Butylspiro[2.5]Octa-4,7-Dien-6-One as a Mechanistic Probe for Single Electron Transfer." Thesis, Virginia Tech, 1998. http://hdl.handle.net/10919/36888.

Full text

Abstract:

<p> Single electron transfer (SET) mechanisms are becoming ubiquitous in modern organic chemistry. However, it is often difficult to distinguish SET mechanisms from polar mechanisms. Kinetics, products and product distributions, and response to perturbation in solvent and substituents are often identical between the two mechanisms. Detection techniques such as EPR, CIDNP, and UV absorption can often detect "blind" pathways and thus cannot provide unambiguous evidence regarding the true mechanism of interest. In recent years mechanistic probes have been developed which can test for si

APA, Harvard, Vancouver, ISO, and other styles

13

Mandai, Kyoko. "Cu-Catalyzed Enantioselective Allylic Substitutions with Organomagnesium and Organoaluminum Reagents Promoted by N-Heterocyclic Carbenes for the Formation of Quaternary Stereogenic Centers." Thesis, Boston College, 2010. http://hdl.handle.net/2345/1329.

Full text

Abstract:

Thesis advisor: Amir H. Hoveyda<br>Chapter One: An overview of Cu-catalyzed enantioselective allylic substitutions with organometallic reagents. Chapter Two: Development of Cu-catalyzed enantioselective allylic alkylations of allylic chlorides with Grignard reagents for the formation of all-carbon quaternary stereogenic centers is disclosed. Chapter Three: Development of Cu-catalyzed enantioselective allylic substitutions of allylic phosphates with alkyl, aryl, and heterocyclic aluminum reagents for the formation of quaternary stereogenic centers is discussed<br>Thesis (MS) — Boston College, 2

APA, Harvard, Vancouver, ISO, and other styles

14

Andersson, Hans. "Reaction between grignard reagents and heterocyclic N-oxides synthesis of substituted pyridines, piperidines and piperazines /." Doctoral thesis, Umeå : Department of Chemistry, Umeå University, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-25619.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Dixon, Craig E. "Studies of the reactivity of tetramesitylgermasilene, (i) the formation of alkene cycloadducts. (ii) the addition of grignard reagents to the silicon-germanium double bond." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq28484.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Naeemi, Qaseem [Verfasser]. "Studies in Enantioselective Transition Metal Catalysis Using Modular Phosphine-Phosphite Ligands Copper-catalyzed 1,4-Addition of Grignard Reagents to alpha,beta-Unsaturated Carbonyl Compounds / Qaseem Naeemi." München : Verlag Dr. Hut, 2012. http://d-nb.info/1020299428/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Riva, E. "FLOW CHEMISTRY APPLIED TO THE PREPARATION OF SMALL MOLECULES POTENTIALLY USEFUL AS THERAPEUTIC AGENTS." Doctoral thesis, Università degli Studi di Milano, 2010. http://hdl.handle.net/2434/155261.

Full text

Abstract:

In recent years, despite the large amount of novel and clinically validated targets identified from the human genome project, the number of new drug launched on the market is decreasing and the overall costs for the development of a drug are rising significantly. Pharmaceutical and biotechnology companies are under a strong pressure to produce a steady stream of innovative, well-differentiated drugs with a reduced cost both for discovery and development. Currently it takes an estimated 10-14 years to develop and market a drug at a cost that exceeds 1 billion dollars. With the aim at increasin

APA, Harvard, Vancouver, ISO, and other styles

18

Zhang, Yiqun. "Stereochemistry of small molecules: Configurational and conformational control." Diss., Virginia Tech, 2007. http://hdl.handle.net/10919/26535.

Full text

Abstract:

Stereochemistry is important aspect of chemistry that customarily includes the study of the relative spatial arrangement of atoms within molecules (static stereochemistry), and the study of the stereochemical requirements and outcomes of chemical reactions (dynamic stereochemistry). These two branches complement each other in modern stereochemistry. Chiral organometallics feature prominently in organic synthesis as reactive intermediates. The possibility of exploring their stereochemistry in synthesis is associated with the configurational stability of the metal-bearing stereogenic center. We

APA, Harvard, Vancouver, ISO, and other styles

19

Hirner, Sebastian. "New Methodologies in Organic Chemistry: Applications to the Synthesis of α-Amino Acids and Natural Products". Doctoral thesis, KTH, Organisk kemi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-11112.

Full text

Abstract:

This thesis deals with the development and application of new synthetic methodology in organic chemistry. The first part describes the development of a new protocol for the synthesis of 3-pyrrolines by means of a microwave-assisted ring-expansion reaction of 2-vinylaziridines. In addition, this methodology is implemented as a key-step in a formal total synthesis of the antibiotic (-)-anisomycin. In the second part, a new methodology for the synthesis of arylglycines from Weinreb amides is described. In this procedure, a Grignard reagent is added to the iminium ion formed from the Weinreb amide

APA, Harvard, Vancouver, ISO, and other styles

20

Milton, Edward J. "Pd catalysed C-C & C-O bond formation using bis-(dialkyl/diarylphosphino)ferrocene ligands." Thesis, University of St Andrews, 2010. http://hdl.handle.net/10023/1022.

Full text

Abstract:

A brief introduction explaining phosphine ligand properties, Pd catalysed cross-coupling reactions; the importance of the steps involved in the catalytic cycle (oxidative addition, transmetalation & reductive elimination), mechanistic studies and a comparison of various reactions will give an overview of important cross-coupling reactions and their limitations. The development of a “super-concentrated” (5M) Pd catalysed Kumada type coupling reaction has been developed for coupling a range of aryl bromide and chloride substrates with the Grignard reagents ((p-CF₃-C₆H₄)MgBr)) and PhMgBr in methy

APA, Harvard, Vancouver, ISO, and other styles

21

Aissaoui, Regadia. "Réaction de substitution nucléophile aromatique des acides naphtoïques ortho-fluorés/méthoxylés avec les réactifs de Grignards et les organolithiens (SNArAB)." Phd thesis, Université du Maine, 2012. http://tel.archives-ouvertes.fr/tel-00684960.

Full text

Abstract:

Dans ce travail, il est montré que les alkyl/vinyl/aryl lithiens et magnésiens réagissentavec les acides C-1(F/OMe) naphtoïques en l'absence de catalyseur métallique. Cette nouvelleréaction de substitution nucléophile aromatique permet potentiellement de préparer n'importequel biaryle tout en s'affranchissant des étapes de protection et de déprotection de la fonctionacide (CO2H). Les alkyllithiens linéaires et ramifiés réagissent avec la même efficacité que lesalkylmagnésiens même à basse température (-78 °C). Le déplacement d'un fluor ou d'unméthoxy s'effectue avec la même facilité. L'absence

APA, Harvard, Vancouver, ISO, and other styles

22

Caillé, Julien. "Réactivité d’organométalliques sur des nitriles fonctionnalisés : réactions de cyclopropanation asymétrique et double addition." Thesis, Le Mans, 2017. http://www.theses.fr/2017LEMA1028.

Full text

Abstract:

Les cyclopropanes sont des motifs structuraux importants en chimie médicinale. Parmi les synthèses existantes du fragment aminocyclopropane, les réactions dérivées de la réaction de Kulinkovich, appliquées aux amides et aux nitriles, sont des méthodes simples d'accès. Cependant, il n'existe pas de version asymétrique efficace. Dans une première partie, l'étude de l'utilisation de complexes de titane optiquement actifs pour la préparation de spirolactames chiraux à partir de cyanoesters a été réalisée. Ce travail a permis de mettre au point une méthode d'évaluation rapide de ligands chiraux don

APA, Harvard, Vancouver, ISO, and other styles

23

Boukattaya, Fatma. "Addition d'organomagnésiens sur des nitriles fonctionnalisés : application à la synthèse de molécules d’intérêt biologique." Thesis, Le Mans, 2016. http://www.theses.fr/2016LEMA1007.

Full text

Abstract:

L’addition nucléophile des réactifs de Grignard sur les nitriles conduit généralement aux cétones après hydrolyse acide. La double addition, menant à des carbinamines tertiaires après traitement, est beaucoup plus difficile et ne s’effectue habituellement qu’avec les organomagnésiens allyliques. Dans ce contexte, nous avons découvert que les organomagnésiens peuvent effectuer une double addition sur la fonction nitrile des acylcyanhydrines, pour fournir des hydroxyamides. Cette réaction est originale par le fait qu’une large gamme d’organomagnésiens peut être utilisée, dans des conditions part

APA, Harvard, Vancouver, ISO, and other styles

24

Li, Chao-Jun. "Part I: Barbier-grignard type reactions in aqueous media; part II: Development of a new tellurium reagent for organic synthesis." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=70267.

Full text

Abstract:

Organometallic reactions, including allylation, alkylation, aldol and Reformatsky type reactions of carbonyl compounds in aqueous media mediated by Sn, Zn, Mn, and In were studied. The possible mechanism and stereochemistry of these reactions were investigated. The methodology has successfully been applied to the syntheses of 1,3-butadienes, vinyloxiranes, and methylenetetrahydrofurans; and the syntheses of natural product (+)-muscarine, (+)-epimuscarine, (+)-KDN and (+)-KDO.<br>A novel tellurium reagent, bis(triphenylstannyl)telluride, for organic synthesis was developed. Its application in t

APA, Harvard, Vancouver, ISO, and other styles

25

Husain, Shabbir. "Mixed Matrix Dual Layer Hollow Fiber Membranes For Natural Gas Separation." Diss., Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/16178.

Full text

Abstract:

Mixed matrix membranes offer an attractive route to the development of high performance and efficiency membranes required for demanding gas separations. Such membranes combine the advantageous processing characteristics of polymers with the excellent separation productivity and efficiency of molecular sieving materials. This research explores the development of mixed matrix membranes, namely in the form of asymmetric hollow fiber membranes using zeolites as the molecular sieving phase and commercially available high performance polymers as the continuous matrix. Lack of adhesion between th

APA, Harvard, Vancouver, ISO, and other styles

26

Koller, Sebastian [Verfasser], Lukas [Akademischer Betreuer] Hintermann, Lukas [Gutachter] Hintermann, and Klaus [Gutachter] Köhler. "Applications of Dehydrogenative and Borrowing Hydrogen Catalysis and Investigation of the Menthyl Grignard Reagent for the Synthesis of Chiral Phosphine Ligands / Sebastian Koller ; Gutachter: Lukas Hintermann, Klaus Köhler ; Betreuer: Lukas Hintermann." München : Universitätsbibliothek der TU München, 2019. http://d-nb.info/121172512X/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Neouchy, Zeïna. "Couplage croisé d’éthers d’énol méthyliques par activation de liaisons C(sp2)-OCH3 catalysée par le nickel et Synthèse d’amines α-trifluorométhylées acycliques optiquement activespar réarrangement de β-aminoalcools α-trifluorométhylés". Thesis, Paris Sciences et Lettres (ComUE), 2018. http://www.theses.fr/2018PSLET016.

Full text

Abstract:

En chimie organique, le développement de méthodes de synthèse robustes et respectueuses de l’environnement a toujours été un défi. De plus, en chimie médicinale, la mise au point de méthodes de synthèse de synthons fluorés de haute valeur ajoutée sont importantes pour avoir accès à des composés bioactifs. Dans ce manuscrit, nous présentons des méthodes efficaces et faciles à mettre en œuvre pour la formation de liaisons carbone-carbone catalysée par le nickel et la formation de liaisons carbone hétéroatome par un réarrangement de β aminoalcools α-trifluorométhylés.Nous avons montré que le coup

APA, Harvard, Vancouver, ISO, and other styles

28

Youssefi, Mohammad. "Recherche de nouvelles synthèses de sélénophosphonates : Préparation et étude de la réactivité d'ène-phosphoramides fonctionnels." Nancy 1, 1986. http://www.theses.fr/1986NAN10105.

Full text

Abstract:

La recherche d'une méthode de synthèse de phénylséléno phosphate d'alkyle (RO)::(2)P(O)CH::(2)SePh a permis de trouver un nouveau réactif de Grignard (ETO)::(2)P(O)CH::(2)MGCL. Les propriétés de ce nouveau réactif ont été étudiées et comparées à celles des autres organométalliques correspondants connus lithiens et cuivreux. Ce réactif de Grignard conduit à une synthèse originale de sélénophosphonates. Utilisation des phosphates d'alkyle comme agents d'alkylation pour la synthèse de dithioesters. Des énephosphoramides fonctionnels ont été obtenus pour la première fois et la réactivité carboniqu

APA, Harvard, Vancouver, ISO, and other styles

29

Alvarez, Gonzalez Eleuterio. "Substitution d'ethers et d'alcools allyliques par differents nucleophiles en presence de complexes de nickel(0) : synthese stereoselective des dienes-1,4 a partir des sulfones dieniques avec le chlorure d'isopropylmagnesium en presence de sels de." Paris 6, 1987. http://www.theses.fr/1987PA066064.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Le, Tin Thanh. "Métallation et substitution nucléophile aromatique des acides benzoïques non protégés : application à la synthèse totale de l’apogossypol." Thesis, Le Mans, 2011. http://www.theses.fr/2011LEMA1016/document.

Full text

Abstract:

Dans le cadre d’un projet général concernant l’étude de la réactivité des acidesbenzoïques non protégés avec les organométalliques, la synthèse totale d’analoguesstructuraux de l’apogossypol mettant en jeu des réactions de métallation aromatique a étéétudiée ainsi que la réaction de substitution nucléophile aromatique des acides benzoïquesortho-fluorés et ortho-méthoxylés.Le gossypol, (1,1’,6,6’,7,7’-hexahydroxy-5,5’-di-iso-propyl-3,3’-diméthyl-2,2’-binaphtalène-8,8’-dicarboxaldéhyde), pigment principal des graines du cotonnier, existe sousla forme de deux atropoisomères et possède de multiple

APA, Harvard, Vancouver, ISO, and other styles

31

MEI, NAI-WEN, and 梅乃文. "Nickel-catalyzed reactions of dithioacetals with Grignard reagents." Thesis, 1990. http://ndltd.ncl.edu.tw/handle/29535739533988080941.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

ZENG, YI-LING, and 曾憶玲. "Nickel-catalyzed reactions of orthothioesters with Grignard reagents." Thesis, 1990. http://ndltd.ncl.edu.tw/handle/84055745170760137304.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

"Nickel-catalyzed coupling reaction of dithioacetals with grignard reagents." Chinese University of Hong Kong, 1989. http://library.cuhk.edu.hk/record=b5886202.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Tung, Hsiao-Hsien, and 董孝先. "Nickel-Catalyzed Certain Cyclic Allylic Thioethers with Grignard Reagents." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/33959115583152332899.

Full text

Abstract:

碩士<br>國立臺灣大學<br>化學學系<br>81<br>The nickel catalyzed reactions of 4-substituted-5,6-2H- hiopyran and 2-vinyltetrahydrothiophenes have been investigatedn details. These substrates have two different kinds of C-S bondone is allylic and the other simple aliphatic. The reactions of-substituted-5,6-2H-thiopyrans afforded mainly vinylcyclopropanesThe oxidative addition with the nickel catalyst would occuracily at the allylic C-S bond would undergo further cleavageielding metallocycles followed by

APA, Harvard, Vancouver, ISO, and other styles

35

Lin, Yu Mei, and 林育玫. "The reaction of the B-nitrostyrene and Grignard reagents." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/32864345971223955378.

Full text

Abstract:

碩士<br>國立臺灣師範大學<br>化學系<br>84<br>Reactions of β-nitrostyrene and Grignard Reagents gave 1,4-adducts(nitronates) at -20 ℃.Futher manipulation of the nitronate were demostrated as follows:(1) treatment of the nitronates with 0 ℃ 5% HCl(aq) generated nitroalkanes. (2) tretment of the nitronates with 0 ℃ 85% H2SO4(aq)generated caboxylic acids. (3) tretment of the nitronates with 0℃ conc. HX(aq) generated hydroximoyl halides. Hydroximoyl halides could convert to nitrile oxide in the presence of ba

APA, Harvard, Vancouver, ISO, and other styles

36

陸天堯. "Nickel-Catalyzed Cross Coupling of Various Substituted Cyclopropyl Grignard Reagents with Dithioacetals." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/00217869243300206173.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Yuan, Tien-Min, and 袁天民. "Study on Chelation Assisted Reaction of Acetals and Dithioacetals with Grignard Reagents." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/04957912568919556295.

Full text

Abstract:

博士<br>國立臺灣大學<br>化學學系<br>82<br>The nickel-catalyzed reactions of allylic dithioketals with excess MeMgI give the geminal dimethylation products in good yields. t-Butylstyrenes and related compounds are synthesized stereoselectively. The formation of a chelation complex results in the enhancement of the reactivity of the nickel-catalyzed cross coupling reaction of aliphatic dithioacetals with Grignard reagents. Various neighboring heteroatom substituents can facilitate the olefination of a di

APA, Harvard, Vancouver, ISO, and other styles

38

You, Chun-Chi, and 尤春祺. "Nickel-Catalyzed Cross Coupling of Various Substituted Cyclopropyl Grignard Reagents with Dithioacetals." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/38020055588036488584.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

程淑媚. "Ultrasound Promoted Ring-opening of α,β-Unsaturated Dioxolanes with Grignard Reagents". Thesis, 1997. http://ndltd.ncl.edu.tw/handle/03302136913758632238.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Sapountzis, Ioannis [Verfasser]. "New functionalized Grignard reagents and their applications in amination reactions / von Ioannis Sapountzis." 2004. http://d-nb.info/972305696/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Cheng, Wen-Lung, and 鄭文龍. "Reactions of Grignard Reagents with Compounds Containing Carbon- Sulfur and Carbon-Oxygen Bonds." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/25997437876046270175.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Wong, Ken-Tsung, and 汪根欉. "Chelation Assisted Nickel-catalyzed Cross-coupling Reactions of Aliphatic Dithioacetals with Grignard Reagents." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/73889183854863595747.

Full text

Abstract:

博士<br>國立臺灣大學<br>化學學系<br>81<br>The relatively unreactive aliphatic C-S bonds can be activated by at least three methods. First, in the presence of a reactive benzylic dithioacetal which is bening generated into an allylic double bond with respect to the aliphatic ditioacetal, renders further coupling possible.Second, the regioselective formation of the double bond via b-heteroatom elimination constitutes another pathway to activate C-S bonds such that a further cross- coupling can occur. Thi

APA, Harvard, Vancouver, ISO, and other styles

43

Liu, Ju-Tsung, та 柳如宗. "Ⅰ.Reactions of β-Nitrostyrenes with Organoboranes or Grignard Reagents Ⅱ.Amphetamines Analysis by GC-MS". Thesis, 2001. http://ndltd.ncl.edu.tw/handle/90522896343381382566.

Full text

Abstract:

博士<br>國立臺灣師範大學<br>化學研究所<br>89<br>Reaction of β-nitrostyrenes with trialkylboranes under nitrogen to generate alkenes in high yields. The mechanism is proposed to be a free-radical reaction via NO2/ alkyl substitution since the reaction is stimulated by the presence of a trace of oxygen in the nitrogen or tert-butyl peroxide or by photolysis and is retarded or inhibited by the addition of galvinoxyl. Reactions of β-nitrostyrenes and triethylborane or tricyclohexylborane in THF solution at room temperature in the air produce trans-alkenes in high yields. Fair good yields of various (

APA, Harvard, Vancouver, ISO, and other styles

44

"Metallation of 8-methylquinoline." Chinese University of Hong Kong, 1993. http://library.cuhk.edu.hk/record=b5887206.

Full text

Abstract:

by Lawrence Tin-chi Law.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1993.<br>Includes bibliographical references (leaves 96).<br>acknowledgements --- p.iii<br>ABSTRACT --- p.iv<br>CONTENTS --- p.v<br>ABBREVIATION --- p.vii<br>Chapter CHAPTER I --- METALLATION OF 8-METHYLQUINOLINE<br>Chapter 1.1 --- INTRODUCTION --- p.1<br>Chapter 1.1.1 --- A Brief Review of Metal-Alkyl Chemistry --- p.1<br>Chapter 1.1.2 --- General Considerations --- p.2<br>Chapter 1.1.3 --- 8-Methylquinoline as Ligand Precursor --- p.8<br>Chapter 1.1.4 --- Metallations by Organolithium Compounds --- p.9<b

APA, Harvard, Vancouver, ISO, and other styles

45

Chen, Chiar-Dy, and 陳嘉迪. "1.The Substitution Reactions of Organomagnesium Copper Reagents and S,S-Dimethyldithiocarbonate 2. Magnesium Bromide Promoted Intramolecular Cyclization Reactions of Grignard Reagents and Acetals." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/36377329455353330595.

Full text

Abstract:

碩士<br>國立臺灣大學<br>化學系<br>85<br>This thesis contains twe parts: In the first part we discuss the substitution reactions of organomagnesium copper reagents, which were prepaired from Grignard reagents, and the loaner of phosgene, S,S-dimethtldithiocarbonate (DMDTC). We can obtain the disubsti- tuted ketones, even monosubstituted thioesters as products. In the second parts we found that magnesium bromide promoted intramolecular cyclization reactions of Grignard reagents and acetals. By u

APA, Harvard, Vancouver, ISO, and other styles

46

Wu, Pei-Fang, and 吳佩芳. "A Theoretical Study of Face Selectivity in the Reactions of Grignard Reagents with 5-Substituted-2-dicyanomethyleneadamantanes." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/40491841109508707480.

Full text

Abstract:

碩士<br>國立臺灣師範大學<br>化學研究所<br>87<br>The π-facial selectivity in the reactions of 5-substituted-2-dicyanomethyleneadamantanes and 5-aza-2-dicyanomethyleneadamantane N-oxide with the Grignard reagents, CH3MgCl and/or PhCH2MgCl were examined using semiempirical and ab initio calculation. The substituents investigated include -F, -Cl, -Br, -OH, NH2, -OMgCl, -CH3 and -Si(CH3)3. The reactions for all substituents, except the -Si(CH3)3 group, favor syn attack. The calculated syn/anti product ratio for the substituents of -F, -Cl, -Br groups agree well with available experimental results. The results ob

APA, Harvard, Vancouver, ISO, and other styles

47

Yeh, Sue-Min, and 葉素敏. "Chelation Assisied Reactions of Acetals,Ketals and Orthoesters with Grignard Reagents-Selective syntheses of myo-Inositol Derivatives." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/40585062219964316124.

Full text

Abstract:

博士<br>國立臺灣大學<br>化學系<br>85<br>Chelation assisted reactions of acetals,ketals and orthoesters with Grignard reagents afford the corresponding ring-opening products in highly regioselectivity. Contiguous diols can thus be differentiated easily by theses procedures. Reactions of orthoesters of myo-inositol with Grignard reagents yield regio- and stereoselective the corresponding products having a free group at C-1. The regioselectivity is rationalized owning to the presence of 2-methoxy

APA, Harvard, Vancouver, ISO, and other styles

48

YANG, HSUAN, and 楊璿. "Nickel-CDC Catalyzed Kumada Cross-Coupling of Aryl Methyl Ethers with Grignard Reagents via C−O Bond Cleavage." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/9952t6.

Full text

Abstract:

碩士<br>國立中正大學<br>化學暨生物化學研究所<br>106<br>As the second largest renewable energy source in the world, how lignin can be effectively transformed into higher economic crops is the goal pursued by modern scientists. Among them, the functionalization of carbon and oxygen bonds to convert lignin to other compounds is a common method at present. However, the problem is that compared to common carbon and halogen bonds, the higher bond energy of carbon and oxygen bonds leads to less dissociation, so the use of organometallic catalysis can lower the activation energy of the reaction and thus facilitate the

APA, Harvard, Vancouver, ISO, and other styles

49

St-Onge, Miguel. "Synthèse stéréosélective de dérivés pipéridines polysubstitués par fragmentation de Grob." Thèse, 2008. http://hdl.handle.net/1866/3472.

Full text

Abstract:

Dans ce mémoire, il sera question de la formation de dérivés pipéridines en utilisant la fragmentation de Grob. Tout d’abord, une introduction sur les alcaloïdes ainsi que sur l’expertise du groupe Charette associée à leur formation démontrera l’importance de ces composés dans le domaine de la chimie organique. Cela sera suivi par un résumé de la fragmentation de Grob incluant les conditions de réactions utilisées, l’importance de la structure de la molécule initiale, les prérequis stéréoélectroniques ainsi que les modifications qui y ont été apportées. Le chapitre 2 sera dédié au développem

APA, Harvard, Vancouver, ISO, and other styles

50

Lin, Chang-Hui, and 林昌輝. "Chelations of Sulfur and Oxygen Atoms Assisted Cross-Coupling Reactions of Bisdithioacetals with Grignard Reagents in Nickel- Catalyzed Condition." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/69302411591976839588.

Full text

Abstract:

碩士<br>國立臺灣大學<br>化學學系<br>84<br>Aliphatic substituted dithioacetal cannot react with Grignard reagents under nickel-catalyzed conditions. However, they can couple with Grignard reagents in the presence of the the chel- ation effect of heteroatom in their chains or in the presence of the allylic dithioacetals formation during the reaction. Herein, we describe a new procedure to convert bisdithioacetals to the corresponding homoallylic dithioacetals by reacting with silylmethyl Grignard reagent

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!