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1
Hefida, Mohamed G., Mahmoud A. A. Razek, and Hoda A. A. Youssef. "Comparative study between open preperitoneal mesh and Lichtenstein's mesh in inguinal hernia repair." Scientific Journal of Al-Azhar Medical Faculty, Girls 5, no. 2 (2021): 417–21. http://dx.doi.org/10.4103/sjamf.sjamf_57_21.
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Background There is still a great debate regarding the optimal approach for inguinal hernial repair. Objective This study aims to compare between the preperitoneal and Lichtenstein approaches in the management of inguinal hernias. Patients and methods We included 50 cases that were randomly divided into two groups: the first group included 25 cases that underwent the preperitoneal repair, whereas the other group included the remaining cases that underwent Lichtenstein repair. Results Intraoperative bleeding was encountered more in the preperitoneal group. Regarding complications, seroma and scrotal edema were encountered more in the Lichtenstein group (P<0.05). Moreover, chronic inguinal pain was more prevalent in the same group. Conclusion Preperitoneal mesh repair offers more advantages over Lichtenstein repair, especially regarding seroma, scrotal edema, and chronic inguinal pain.
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Mohamed, Sawsan S., and Mohamed O. Alfy. "Use of prophylactic mesh for prevention of incisional hernia following midline laparotomy." Scientific Journal of Al-Azhar Medical Faculty, Girls 5, no. 1 (2021): 28–33. http://dx.doi.org/10.4103/sjamf.sjamf_12_21.
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Background Incisional hernias (IH) following abdominal surgery are frequent and morbid. Prophylactic mesh placement may significantly reduce IH but is not widely used. This study aimed to assess the safety and efficacy of prophylactic mesh placement in preventing IH development after midline laparotomy. Patients and methods This was a prospective observational study on 83 patients undergoing midline laparotomy admitted to our hospital during the period from August 2017 to January 2020. The patients were randomized into two groups: the suture group (SG), with nonabsorbable running sutures, and the prophylactic mesh group, with fascial closure as in the SG but reinforced with onlay polypropylene mesh. Results There was no significant difference observed in mean age, sex, mean BMI, mean hospital stay, and mean follow-up period between both the groups. A statistically significant reduction in IH incidence was demonstrated in the mesh group, with one (2.56%) case, than in the SG, with 11 (25.0%) cases. Surgical site occurrence had higher incidences in the mesh group (25.64%) than in the SG (6.82%). Conclusion Reinforcement of the midline closure by onlay mesh has been proved to be an effective and safe method for avoidance of IH in high-risk patients in both elective and emergency operations during the follow-up period.
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Faraz, Ahmad, Ayaz Gul, Adil Bangash, Shumaila Naseer, Sara Jamil Khan, and Aziz Ur Rehman. "Early Versus Late Repair of Incisional Hernia Following Laparostomy for Enter cutaneous Fistulas Using Component Separation Technique and Onlay Placement of Polypropylene Mesh." Journal of Khyber College of Dentistry 13, no. 1 (March 31, 2023): 28–34. http://dx.doi.org/10.33279/jkcd.v13i1.55.
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Objective: To compare the outcome of early versus late repair of incisional hernia that developed following laparostomy for enterocutaneous fistula. Material and methods: This Randomized controlled trial study was conducted at Surgical C unit, Lady Reading Hospital, Peshawar from 22nd May, 2014 till 21st May, 2017. Following ethical approval, 69 patients were enrolled in the study, amongst which three were lost to follow-up. So, 33 patients in both groups were later on included. In group A, patients were asked to present at an early 3-month delay following confirmation of successful enterocutaneous fistula management after discharge, and Group B patients were asked to come one year later. Both groups were subjected to the same procedure of component separation technique with reinforcement with polypropylene mesh. Data was recorded on a Proforma and post-operative complications were mentioned for a period of 12 months that included seroma/hematoma formation, superficial wound infection, mesh infection, enterocutaneous fistulas, recurrence and mortality. Results: Following allocation to two groups, the group planned for surgery by the component separation technique (CST) in the early group had a slightly smaller hernia (21.3cm) but this was not significant a difference in comparison (p=0.68). The study was focused at a follow-up for duration for one year during which 19 patients (28.7%) in total had clinical or radiological evidence of recurrence of the incisional Hernia out of which ten patients(30.3%) were from group A. Recurrence in group B occurred in 9 patients(27.2%) (p=0.88) This included three patients (4.5%) from both groups with infected meshes that needed removal. Conclusion: Component Separation technique is a feasible staged approach to management of a ventral wall defect (incisional hernia) with reinforcement of the wall with polypropylene mesh in early phase of recovery after enterocutaneous fi stulas.
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Fauzia, Envrinda Arief, and Herry Purnama. "The Effect Of Particle Size On The Characterization Of Activated Carbon From Tropical Black Bamboo (Gigantochloa Atroviolacea)." Techno (Jurnal Fakultas Teknik, Universitas Muhammadiyah Purwokerto) 22, no. 2 (October 14, 2021): 99. http://dx.doi.org/10.30595/techno.v22i2.10350.
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Activated carbon also known as activated charcoal is a common term for carbon materials, which comprises charcoal. Activated carbon has a good adsorption capacity against gases and pollutants in liquids because of its wide surface. The material used in this research was tropical black bamboo, with the variation of particle size -10+20 mesh, -20+40 mesh, -40+60 mesh and -60+80 mesh. There are 2 processes to produce activated carbon, i.e. carbonation and activation. In this research, the carbonation is set at 380°C in 1 hour. Then, each size of carbon was activated by H3PO4 9.8% along 24 hours. The analysis conducted were moisture content, ash content, iodine number, and functional group analysis using Fourier Transform Infrared Spectroscopy (FTIR). The smaller particle size, the more pores will be produced and it caused the surface area higher. The results showed that variation of particle size had effect on the characterization and quality of activated carbon, where moisture content is between 10.60 to 4.05%, ash content is 1% to 0.2% and iodine adsorption is between 710 mg/g to 900 mg/g. In FTIR analysis, it showed that all of the samples had O-H, C=C, and C-O functional group.
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Lambrechts, Adriaan, Christophe Van Dijck, Roel Wirix-Speetjens, Jos Vander Sloten, Frederik Maes, and Sabine Van Huffel. "Preoperative Prediction of Optimal Femoral Implant Size by Regularized Regression on 3D Femoral Bone Shape." Applied Sciences 13, no. 7 (March 29, 2023): 4344. http://dx.doi.org/10.3390/app13074344.
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Preoperative determination of implant size for total knee arthroplasty surgery has numerous clinical and logistical benefits. Currently, surgeons use X-ray-based templating to estimate implant size, but this method has low accuracy. Our study aims to improve accuracy by developing a machine learning approach that predicts the required implant size based on a 3D femoral bone mesh, the key factor in determining the correct implant size. A linear regression framework imposing group sparsity on the 3D bone mesh vertex coordinates was proposed based on a dataset of 446 MRI scans. The group sparse regression method was further regularized based on the connectivity of the bone mesh to enforce neighbouring vertices to have similar importance to the model. Our hypergraph regularized group lasso had an accuracy of 70.1% in predicting femoral implant size while the initial implant size prediction provided by the instrumentation manufacturer to the surgeon has an accuracy of 23.1%. Furthermore, our method was capable of predicting the implant size up to one size smaller or larger with an accuracy of 99.1%, thereby surpassing other state-of-the-art methods. The hypergraph regularized group lasso was able to obtain a significantly higher accuracy compared to the implant size prediction provided by the instrumentation manufacturer.
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WANG, DAJIN. "AN EMPIRICAL STUDY OF HIERARCHICAL DIVISION FOR MESH-STRUCTURED NETWORKS." Journal of Interconnection Networks 08, no. 03 (September 2007): 285–304. http://dx.doi.org/10.1142/s0219265907002028.
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A parallel/distributed system consists of a collection of processes, which are distributed over a network of processors, and work in a cooperative manner to fulfill various tasks. A hierarchical approach is to group and organize the distributed processes into a logical hierarchy of multiple levels to achieve better system performance. It has been proposed as an effective way to solve various problems in distributed computing, such as distributed monitoring, resource scheduling, and network routing. In [21], we studied hierarchical configuration for mesh and hypercube networks to the end of achieving better system performance. In particular, we proposed theoretically optimal hierarchy for mesh and hypercube, so that the total traffic flow over the network is minimized. In this paper, we present the experimental results to establish the practical relevance of mesh hierarchy proposed in [21]. We simulated situations for multi-level division, real network loading scenarios, random data aggregation rates, and different division sizes other than derived in [21]. The simulation results not only show that the analytically obtained hierarchy works well for many realistic settings, but also offer some useful insights into the proposed hierarchy scheme.
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Abduvosidov, Kh A., V. G. Shestakova, A. M. Perevedentseva, I. A. Chekmareva, S. M. Chudnykh, L. M. Baranchugova, A. G. Alekseev, and M. M. Kokoev. "Comparative morphological analysis of connective tissue response to polypropylene endoprosthesis implantation." Сибирский научный медицинский журнал 44, no. 3 (July 4, 2024): 125–34. http://dx.doi.org/10.18699/ssmj20240314.
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Nowadays, the palm of superiority in elective surgery belongs to the problem of hernias. According to the literature worldwide, more than 20 million patients undergo surgical treatment for hernia of the anterior abdominal wall every year, most of whom undergo alloplasty using various kinds of nets. The study of the influence of methods for fixing implants and the emerging local inflammatory response of tissues on the frequency of relapses after allognioplasty is devoted to isolated works. Aim of the study was to investigate in an experiment the characteristics of the reaction of local tissues when implanting a rigid monofilament mesh polypropylene implant with a shape memory effect, and a classic mesh endoprosthesis made of monofilament polypropylene (PP) with various methods of fixing implants. Material and methods. An experimental study on 60 white male Wistar rats was performed to identify tissue reaction features around the PP mesh. Group 1 animals (n = 30) were implanted with a rigid mesh monofilament PP implant (Herniamesh, Italy) with shape memory effect, group 2 animals (n = 30) – with a classic mesh endoprosthesis made of monofilament PP for soft tissue repair ESFIL® standard (Lintex, Russia). Biopsies were examined at 1, 2, 3 months after implantation of the PP mesh. Results. A morphological study showed that 1 month after the implantation of a rigid mesh monofilament PP implant, the inflammatory reaction is less obvious than when implanting a classical PP endoprosthesis. This reaction contributed to the earlier germination of collagen fibers around the rigid implant monofilaments. At 2 and 3 months after the implantation of PP nets in both groups of animals, there were no advantages as the regenerate formed. Conclusions. When introducing PP mesh with suture fixation and rigid monofilament PP mesh without fixation, there is a natural response to the integration of the endoprosthesis, which is characterized by aseptic inflammation followed by pronounced fibrosis around the implant. Such processes, occurring in response to the implantation of synthetic polypropylene nets, increase local mechanical tissue resistance, and can create additional strength against recurrence of inguinal hernias.
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WANG, DAJIN, and JIANNONG CAO. "ON HIERARCHICAL CONFIGURATION OF DISTRIBUTED SYSTEMS ON MESH AND HYPERCUBE." International Journal of Foundations of Computer Science 15, no. 03 (June 2004): 517–34. http://dx.doi.org/10.1142/s0129054104002583.
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We study hierarchical configuration of distributed systems for achieving optimized system performance. A distributed system consists of a collection of local processes which are distributed over a network of processors, and work in a cooperative manner to fulfill various tasks. A hierarchical approach is to group and organize the distributed processes into a logical hierarchy of multiple levels, so as to coordinate the local computation/control activities to improve the overall system performance. It has been proposed as an effective way to solve various problems in distributed computing, such as distributed monitoring, resource scheduling, and network routing. The optimization problem considered in this paper is concerned with finding an optimal hierarchical partition of the processors, so that the total traffic flow over the network is minimized. The problem in its general form has been known to be NP-hard. Therefore, we just focus on distributed computing jobs which require collecting and processing information from all processors. By limiting levels of the hierarchy to two, we will establish the analytically optimal hierarchical configurations for two popular interconnection networks: mesh and hypercube. Based on analytical results, partitioning algorithms are proposed to achieve minimal communication cost (network traffic flow). We will also present and discuss heuristic algorithms for multiple-level hierarchical partitions.
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Ishchenko, Anatolii I., Ailar Asambaeva, Anton A. Ishchenko, Irina D. Khokhlova, Tea A. Dzhibladze, Elena G. Malyuta, Leonid S. Aleksandrov, et al. "Long-term outcomes of surgical interventions for different types of pelvic organ prolapse." V.F.Snegirev Archives of Obstetrics and Gynecology 10, no. 4 (December 19, 2023): 287–97. http://dx.doi.org/10.17816/2313-8726-2023-10-4-287-297.
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Background. The study aimed to comparatively analyze the nature and frequency of complications and the severity of recurrences among patients with different forms of pelvic organ prolapse (POP). These factors will be examined depending on the surgical technique employed.
Materials and methods. The study involved a thorough clinical evaluation, surgical intervention, and outpatient monitoring (at 1, 6, 12, 24, and 36 months) of 523 participants, aged 32–80 years, categorized into four main groups and 3–4 subgroups depending on the type of POP and surgical method used. Group 1 comprised 161 women (30.8%) presenting with grade I–III cervical elongation combined with grade I–II anterior vaginal wall prolapse. Group 2 consisted of 207 (39.6%) patients with grade II–III anterior vaginal wall prolapse, whereas group 3 included 107 patients (20.5%) with complete uterine prolapse. Group 4 was made up of 48 women (9.1%) with grade II–III posterior vaginal wall descent.
Results. Based on the acquired data, synthetic implant extrusion commonly took place 6–12 months after the surgical procedure. Of the 158 patients who received polypropylene endoprostheses, 20 (12.7%) experienced extrusion and required repeated hospitalizations for partial or complete excision, followed by restoration of vaginal wall integrity. POP recurrences typically occurred 12–36 months after surgical treatment and were detected in 69 (13.2%) of 523 patients. The reappearance of symptoms of pelvic organ descent was most commonly identified in patients who underwent surgery using their tissues (26.6%), less frequently with synthetic implants (12.7%), and extremely rarely with titanium endoprostheses (1.6%).
Conclusions. The results revealed that patients, who underwent surgery using original techniques, employing titanium-made mesh implants and anchors, experienced the fewest complications and postoperative POP incidence. Conversely, the use of synthetic implants increases the likelihood of mesh-associated complications and disease recurrence, necessitating partial or complete excision. The use of autologous tissue for POP surgery is related to a higher likelihood of recurring prolapse symptoms.
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Levchuk, A. L., Yu M. Stoiko, and O. Yu Sysoev. "Evaluation of the effectiveness of negative pressure wound therapy in the complex treatment of patients with infected mesh endoprostheses of the anterior abdominal wall." Grekov's Bulletin of Surgery 180, no. 4 (September 23, 2021): 35–40. http://dx.doi.org/10.24884/0042-4625-2021-180-4-35-40.
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Introduction. Wound complications after the placing of various implants of the abdominal wall after hernia repair account for up to 15 % of all hospitalizations with purulent diseases. Their treatment is often accompanied by a high frequency of explantation of a mesh endoprosthesis with a risk of recurrent hernias in this category of patients.The objective of the study was to improve the results of surgical treatment of patients with infected implants of the abdominal wall after herniaplasty based on the assessment of the effectiveness of the negative pressure wound therapy (NPWT).Methods and materials. A retrospective analysis of the treatment results of patients with infected mesh endoprostheses of the anterior abdominal wall (n=68) was carried out. We formed for comparison two homogeneous representative groups of patients, who underwent adequate debridement of a purulent wound with empirical antibiotic therapy. Patients from the study group (n=38) received local therapy using NPWT, patients from the control group (n=30) received traditional local therapy. The evaluation of the treatment results was carried out according to a number of criteria: the course of the systemic inflammatory reaction, the dynamics of reparative processes in the wound of the anterior abdominal wall, evaluation of the clinical outcomes of treatment of patients.Results. The use of vacuum therapy was accompanied by a positive effect on the course of the systemic inflammatory reaction, stimulation of reparative processes in the wound due to the rapid elimination of bacterial agents from the wound cavity (p= 0.003), as well as significant retraction of the wound cavity (p=0.004) compared to traditional methods of wound treatment. Patients from the study group had more favorable treatment outcomes such as a reduction in the duration of hospitalization (p=0.005) and the number of surgical interventions (p=0.003). Due to the NPWT, it was possible to save implants in 30 patients out of 38 (78.9%) with infected mesh endoprostheses of the anterior abdominal wall, which prevented the formation of recurrent hernias and helped to avoid reoperations in this category of patients.Conclusion. The use NPWT is a safe and effective method for treating wounds of the anterior abdominal wall with infected mesh endoprostheses after hernioplasty.
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Choi, In-Oh, Ji-Su Oh, Sang-Joun Yu, Byung-Ock Kim, and Won-Pyo Lee. "Retrospective Analysis of the Effect of Three-Dimensional Preformed Titanium Mesh on Peri-Implant Non-Contained Horizontal Defects in 100 Consecutive Cases." Applied Sciences 11, no. 2 (January 19, 2021): 872. http://dx.doi.org/10.3390/app11020872.
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This study aimed to clinically and radiographically evaluate the results of guided bone regeneration (GBR) using three-dimensional preformed titanium mesh (3-D-PFTM) for non-contained horizontal defects in 100 consecutive cases. This study involved 100 patients (129 implants) with peri-implant non-contained horizontal defects. The patients were divided into three groups: 3-D-PFTM alone (Group 1), 3-D-PFTM plus cross-linked collagen membrane (Group 2), and 3-D-PFTM plus non-cross-linked collagen membrane (Group 3). Each implant was evaluated radiographically using CBCT at baseline and 6 months postoperatively. At the platform level, the mean horizontal hard tissue gain of all the sites was 3.1 ± 1.3 mm at 6 months postoperatively. The mean rate of mesh exposure was 11.8% in Group 1, 4.2% in Group 2, and 5.0% in Group 3. The mean hard tissue gain rate was 71.0 ± 23.0% in group 1, 84.2 ± 21.5% in group 2, and 84.0 ± 22.9% in group 3. Groups 2 and 3 showed significantly higher hard tissue gain rates than group 1. However, there was no significant difference between the rates in groups 2 and 3. Within the limitations of this study, 3-D-PFTM should be considered as a valuable option for GBR for peri-implant non-contained horizontal defects. The use of an additional resorbable collagen membrane provides additional advantages.
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Gimranov, Valiyan, Evgeny Skovorodin, Ilnara Abyzgildina, Foat Karimov, and Aidar Bagautdinov. "Morphological indicators of subcutaneous implantation of monofilament mesh." Veterinarska stanica 51, no. 4 (June 12, 2020): 363–74. http://dx.doi.org/10.46419/vs.51.4.1.
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Hernias are a significant, non-infectious animal condition. In productive animals, failure to provide surgical treatment leads to premature rejection and potential loss of their productive longevity. In small pets, this becomes a social problem for pet owners related to the keeping and death of affected animals. The aim of this study was to study the histological parameters of tissues during implantation of monofilament mesh in cattle for periods up to four months. The study was conducted on eight bulls of the Black Motley breed, divided into two groups of four animals. In the first group, four bulls received a subcutaneous implant of hernioplasty mesh made of polypropylene monofilament (Herniamesh S.R.I. Via CiRie 22 / A, San Maruro Torinese, Torino, Italy) in the area of the lateral soft abdominal wall on the right and left sides. In the second group, four bulls received implants in the middle third of the neck to the right and left sides. Thus, the subject of research was 16 wounds with implanted mesh. A sterile piece monofilament mesh, 1x2 cm in size and folded in half along the longitudinal side, was inserted vertically into the formed hypodermic pocket on the right side of the wound, in which it was possible to freely place the specified mesh. During the course of the study, Polycon No. 4 thread with intermittent knotted seams was used, and three sutures were applied. To ensure fixation of the mesh, it was stitched centrally. The material for histological studies was taken by biopsy at one, two, three and four months after implantation. Tissue was embedded in paraffin blocks, and sections were stained with haematoxylin-eosin and picrofuchsin according to Van Gieson. The results indicated that after subcutaneous implantation of monofilament mesh in the neck and abdominal wall in cattle, wound healing occurs by primary intention. It was revealed that from the beginning of the histological study to one month, the monofilament mesh is first overgrown with loose connective tissue. By the end of the study, after four months, this is sequentially differentiated into dense connective tissue. No significant differences were observed between the abdominal wall and neck area as sites of implantation, and morphological processes in both sites proceeded in the same way. Thus, the conducted studies allow us to conclude that monofilament mesh is a suitable material for closing the hernial ring in cattle, where it is not possible to use their own tissues for these purposes.
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Bereshchenko, V. V., A. N. Lyzikov, E. A. Nadyrov, and A. N. Kondrachuk. "COMPARATIVE MORPHOLOGICAL FEATURES OF SUBCUTANEOUS TISSUE OF EXPERIMENTAL ANIMALS IN RESPONSE TO THE IMPLANTATION WITH MODIFIED POLYPROPYLENE MESH ENDOPROSTHESIS." Novosti Khirurgii 29, no. 6 (December 22, 2021): 645–53. http://dx.doi.org/10.18484/2305-0047.2021.6.645.
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Objective. To study cellular and tissue reactions in experimental animals in response to the implantation of a polypropylene mesh endoprosthesis modified with a polycaprolactone solution by the different methods. Methods. The object of the study was modified with polypropylene mesh endoprostheses implanted in experimental animals. The animals were divided into three groups: the control group - with polypropylene mesh endoprosthesis without its modification; the first experimental group - with polycaprolactone modification by its uniform distribution on the endoprosthesis surface; the second experimental group - with the samples of polypropylene mesh endoprosthesis modified by method of electrospinning. The morphological assessment of reactions to the implantation of the materials was carried out by means of the calculation of the cellular elements of inflammatory and connective tissue origin along the periphery of the implants Results.A statistically significant increase in the number of fibroblasts was revealed on the 3<sup>rd</sup> day of observation in the animals of the second experimental group in comparison with the control one (р=0,047). The analogous trend was noted on the 7<sup>th</sup> day of the study in comparison with the control animals (р=0,002), as well as with the animals from the first experimental group (р<0,001). On the 7<sup>th</sup> day of the experiment the enhancement of the fibroplastic properties of the samples modified with polycaprolactone by electrospinning was characterized by a less pronounced inflammatory reaction of the peripheral tissues and it indicates a higher rate of granulation tissue maturation. Conclusion. Tissue and cellular reactions around the specimens modified with with polycaprolactone solution by the electrospinning method were found to be characterized by a less pronounced inflammatory reaction of the peripheral tissues and more expressed fibroplastic reaction in comparison with the control specimens. The endoprostheses obtained in this way can be used to stimulate the migration of fibroblasts and enhance local collagen synthesis, accelerate the processes of reparative regeneration in patients with undifferentiated connective tissue dysplasia. Thus it makes possible to recommend introducing this method of PSE modification in clinical practice. What this paper adds For the first time, morphological features of subcutaneous tissue around samples of polypropylene mesh endoprostheses modified with polycaprolactone solution by the different methods of its application have been studied. The changes in tissues around the samples of polypropylene mesh endoprostheses modified with a polycaprolactone solution by electrospinning are found to be characterized by a low peripheral inflammatory response of tissues with an increase of fibroplastic changes in comparison with control ones.
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Choi, Byul-Bora, Seung-Ah Park, Jeong-Hae Choi, Sang-Rye Park, and Gyoo-Cheon Kim. "Evaluation of Dentin Tubule Occlusion Using Pre-Treatment with No-Ozone Cold Plasma: An In Vitro Study." Applied Sciences 13, no. 21 (October 26, 2023): 11728. http://dx.doi.org/10.3390/app132111728.
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Dentin hypersensitivity is a common disease of the oral cavity, which renders the tooth extremely sensitive to stimuli. These symptoms usually result from the exposure of the dentinal tubules to the external environment. There is a need for a treatment for dentinal hypersensitivity that can overcome the shortcomings of the existing agents. This study thus aimed to assess the therapeutic efficacy of no-ozone cold plasma (NCP), which was developed for safe use in the oral cavity, in conjunction with 1.23% acidulated phosphate fluoride (APF) and hydroxyapatite (HA), which are widely used conventional treatments of hypersensitivity. The fluoride content was evaluated using electron probe micro-analyzer (EPMA) analysis. Moreover, we confirmed the effect of NCP pre-treatment on the dentinal tubule occlusion by APF and HA as follows: scanning electron microscopy and energy dispersive X-ray spectrometry were employed to analyze the exposed dentinal tubules, and the calcium and phosphorus content were measured. Furthermore, an additional experiment was conducted using a metal mesh to analyze the working elements of NCP. All experimental results were analyzed by one-way analysis of variance and then by using the Turkey test as a post hoc test. EPMA analysis confirmed that the fluoride content of the APF and NCP group was significantly higher than that of the APF group (p < 0.001). The fluoride content of the group treated with APF and NCP equipped with a metal mesh was significantly lower than that in the group treated with APF and NCP and the group treated with APF and NCP equipped with a cotton mesh (p < 0.01). Moreover, the group treated with NCP pre-treated with HA and APF exhibited significantly greater dentinal tubule occlusion than the other groups (p < 0.05). The same result was confirmed by calculating the calcium/phosphorus ratio (p < 0.05). Pre-treatment of the enamel and dentin surfaces with plasma improved hypersensitivity by enhancing fluoride deposition with APF and dentinal tubule occlusion with HA.
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Hovgård, Holger, Hans Lassen, Niels Madsen, Thomas Moth Poulsen, and David Wileman. "Gillnet selectivity for North Sea Atlantic cod (Gadus morhua): model ambiguity and data quality are related." Canadian Journal of Fisheries and Aquatic Sciences 56, no. 7 (July 1, 1999): 1307–16. http://dx.doi.org/10.1139/f99-070.
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Gillnet selectivity curves for North Sea Atlantic cod (Gadus morhua) were fitted to catch data obtained with six different mesh sizes. The selectivity curves investigated included frequently used selectivity models following the normal, lognormal, and gamma distributions. Another group of selectivity models that take the method of capture (gilled, maxillae, or "randomly" enmeshed) into consideration was also included. The best description of the selection data was found for the latter models. Therefore, the capture processes and girth measurements should be recorded as a matter of routine and such data used when constructing and evaluating gillnet selectivity models. The shape of the selectivity curve for those size intervals where there were satisfactory catch information was well defined, while the selection curve was ambiguous outside the interval with adequate data. Ambiguities in the shape of the selectivity curve can be diminished by choosing an appropriate range in mesh sizes and ensuring that the mesh sizes match the size distribution of the population fished. It is furthermore suggested that the estimated length distribution of the fish encountering the nets be robust to misspecification of the selectivity model.
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Attié, David, Stephan Aune, Eric Berthoumieux, Francesco Bossù, Paul Colas, Alain Delbart, Emmeric Dupont, et al. "Current Status and Future Developments of Micromegas Detectors for Physics and Applications." Applied Sciences 11, no. 12 (June 9, 2021): 5362. http://dx.doi.org/10.3390/app11125362.
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Micromegas (MICRO-MEsh GAseous Structure) detectors have found common use in different applications since their development in 1996 by the group of I. Giomataris and G. Charpak. In this review article, we present implementations of Micromegas sub-detectors in different physics experiments and highlight the current state of development for innovative detection concepts with Micromegas.
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Lukoyanychev, E. E., S. G. Izmajlov, A. E. Leontev, A. A. Mironov, V. O. Nikolskij, D. A. Evsjukov, and V. A. Emelyanov. "Pharmacological support in the perioperative period of implantation of a polypropylene mesh prosthesis (experimental study)." Research and Practical Medicine Journal 9, no. 1 (February 18, 2022): 91–102. http://dx.doi.org/10.17709/2410-1893-2022-9-1-8.
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Purpose of the study. was to improve the technology of prosthetic repair of the anterior abdominal wall patients with hernias by means of pharmacological regulation of the local and systemic inflammatory response and stimulation of reparative regeneration.Materials and methods. The study was carried out on 52 pure line rats in vivarium. All animals have on-lay implantation of a polypropylene mesh imlantant. Group I have no specific pharmacological treatment receive (0.9 % sodium chloride solution); group II – receive solution of xymedon, group III – potassium orotate, group IV – methyluracil.Results. Identified that all investigated drugs of the pyrimidine series (xymedon, potassium orotate, methyluracil) have a significant effect on the local and systemic inflammatory process. The growth of IL 10 and TNF-a are associated with an increase in the area of liquid inclusions. The use of potassium orotate and methyluracil in the postoperative period is inappropriate, as it is associated with an increased risk of hemorrhage and acute paraprosthetic fluid accumulations. Taking xymedon after surgery is associated with an accelerated growth of blood vessels and granulation tissue, a decrease in fluid inclusions, but is associated with an insignificant increase in the risk of tissue hemorrhage.Conclusion. Pharmacological regulation of inflammatory and regenerative processes with xymedon in the perioperative period of prosthetic repair could guide the development of surgical treatment of patients with abdominal hernias, which requires further clinical study.
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Седых, И. В., Д. Э. Смоленский, and Д. С. Назаренко. "ЭКСПЕРИМЕНТАЛЬНОЕ ПОДТВЕРЖДЕНИЕ РАБОТОСПОСОБНОСТИ КАПИЛЛЯРНОГО ЗАБОРНОГО УСТРОЙСТВА (СЕТЧАТОГО РАЗДЕЛИТЕЛЯ) ПРИ ПРОГРАММНОМ РАЗВОРОТЕ." Journal of Rocket-Space Technology 26, no. 4 (September 5, 2018): 112–19. http://dx.doi.org/10.15421/451821.
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One of the problems of providing a group launch of spacecraft is to ensure the re-launch of the propulsion engine for the transition to another orbit, after the separation of the first vehicle. When the spacecraft is separated into a stage, an acceleration is applied directed toward the bottom of the tank and leading to an outflow of the fuel component from the mesh separator. This, in turn, leads to the denudation of the mesh separator and the penetration of gas under it, which can lead to a breakdown of the launch of the engine. In viewof the complexity of the hydrodynamic processes taking place in the tanks, experimental confirmation of the mesh separators chosen during the design is required.In this paper, we describe the methods for determining the model conditions (the choice of the scale of the experimental design, the type of the model fluid, the magnitude of the accelerations, etc.), a description of the stand designed specifically for the test data, and the results of the experimental confirmation of the capillary sampling device performance in the separation of the spacecraft. The results of the performed works confirm the correctness of the decisions made in the development of capillary sampling devices.
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Mäki, Mari, Jussi Heinonsalo, Heidi Hellén, and Jaana Bäck. "Contribution of understorey vegetation and soil processes to boreal forest isoprenoid exchange." Biogeosciences 14, no. 5 (March 8, 2017): 1055–73. http://dx.doi.org/10.5194/bg-14-1055-2017.
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Abstract. Boreal forest floor emits biogenic volatile organic compounds (BVOCs) from the understorey vegetation and the heterogeneous soil matrix, where the interactions of soil organisms and soil chemistry are complex. Earlier studies have focused on determining the net exchange of VOCs from the forest floor. This study goes one step further, with the aim of separately determining whether the photosynthesized carbon allocation to soil affects the isoprenoid production by different soil organisms, i.e., decomposers, mycorrhizal fungi, and roots. In each treatment, photosynthesized carbon allocation through roots for decomposers and mycorrhizal fungi was controlled by either preventing root ingrowth (50 µm mesh size) or the ingrowth of roots and fungi (1 µm mesh) into the soil volume, which is called the trenching approach. Isoprenoid fluxes were measured using dynamic (steady-state flow-through) chambers from the different treatments. This study aimed to analyze how important the understorey vegetation is as a VOC sink. Finally, a statistical model was constructed based on prevailing temperature, seasonality, trenching treatments, understory vegetation cover, above canopy photosynthetically active radiation (PAR), soil water content, and soil temperature to estimate isoprenoid fluxes. The final model included parameters with a statistically significant effect on the isoprenoid fluxes. The results show that the boreal forest floor emits monoterpenes, sesquiterpenes, and isoprene. Monoterpenes were the most common group of emitted isoprenoids, and the average flux from the non-trenched forest floor was 23 µg m−2 h−1. The results also show that different biological factors, including litterfall, carbon availability, biological activity in the soil, and physico-chemical processes, such as volatilization and absorption to the surfaces, are important at various times of the year. This study also discovered that understorey vegetation is a strong sink of monoterpenes. The statistical model, based on prevailing temperature, seasonality, vegetation effect, and the interaction of these parameters, explained 43 % of the monoterpene fluxes, and 34–46 % of individual α-pinene, camphene, β-pinene, and Δ3-carene fluxes.
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Vorovskyі, О. О., V. O. Shaprynskyі, and I. M. Sadyk. "Morphological changes of a great omentum at implantation of polypropylene and composite prostheses at allohernioplasty." Reports of Morphology 25, no. 4 (December 19, 2019): 62–69. http://dx.doi.org/10.31393/morphology-journal-2019-25(4)-10.
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To date, allohernioplasty of giant postoperative ventral hernias retains high postoperative mortality and a significant number of postoperative complications. The purpose of the study is to investigate the possibility of intraperitoneal use of polypropylene and composite implants in allohernioplasty of postoperative giant ventral hernias by studying the morphological changes of the great omentum. The results of surgical treatment of 146 patients with postoperative giant ventral hernias were investigated. To this group of patients with allohernioplasty by the method onlay was performed 22 (15.1%) patients, by the method sublay – 46 (31.5%), by the method inlay – 52 (35.6%), with intra-abdominal placement of the mesh by the method onlay (intraperitoneal onlay mesh) – 26 (17.8%). 32 (21.9%) patients who underwent surgery using the sublay method polypropylene implant was fenced off from the abdominal organs with a great omentum, 22 (15.1%) patients operated on by the intraperitoneal onlay mesh method composite implant was also fenced off from the abdominal organs by a great omentum. In 8 (5.5%) patients from the group of patients who were operated on by the sublay method and in 6 (4.1%) – operated by the intraperitoneal onlay mesh method for 14-18 days patients developed signs of chronic intestinal obstruction, where the cause was postoperative adhesive illness. The study of the effect of polypropylene prosthesis on a great omentum was performed on 8 outbred dogs and 6 outbred mature dogs, who were implanted with a composite mesh unilaterally covered with oxycellulose. The polypropylene implant has been shown to have a greater capacity for the development of adhesive processes. However, if a great omentum to protect this prosthesis from the abdominal cavity then the first zone (active inflammation) spread in 155 microns (increase in the number of blood capillaries of the microcirculatory bed, thickening of the arterioles wall, venous full blood flow, diapedesis of leukocytes through the wall of the blood cells), the second zone (sclerosis) – up to 40 microns (increase in the number of macrophages and lymphocytes. proliferation of fibroblasts). In the future, the structure of the omentum was almost indistinguishable, so with allohernioplasty by the developed method, it was possible to prevent the development of adhesive disease on the intestine. This study confirmed the limited spread of the inflammatory response, which allows the implant of a polypropylene mesh on a great omentum. In the composite mesh, the composite mesh was spliced with surrounding tissues from the side where there was no gel coating, and from the side of the salivary coating, the “readiness” to spread the inflammatory process (vasculitis with pronounced lympho-plasmocytic infiltration of the vessel walls and perivascular ductus), therefore, left it is also necessary to enclose it with a large omentum from intestium.
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NAKONECHNA, O. A., and O. V. KYSLOV. "8-isoprostane as a marker of oxidative stress in experimental animals after implantation of surgical mesh with a coating based on tantalum and its derivatives." Experimental and Clinical Physiology and Biochemistry 68, no. 4 (2023): 28–34. http://dx.doi.org/10.25040/ecpb2023.04.028.
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Nowadays, the world observes the problem of adhesion process after implantation of polypropylene surgical meshes, which occurs in about 30–40 % of patients in the postoperative period. Over the past 30 years, tantalum and its derivatives have proven themselves as materials for biomedical implants in dentistry and orthopedics. In the future, tantalum-based coatings may become an inhibitor of the development of adhesion and inflammatory processes after surgical mesh implantation. In order to better predict the implantation of biomedical materials, it is important to determine the markers of the development of oxidative stress. A change in the concentration of biomarkers of the state of the oxidants system, in particular 8-isoprostane, can indicate the development of pathological conditions under the conditions of oxidative stress, which can have a significant impact on the viability of cells after surgical intervention. The aim of the study is to determine the concentration of 8-isoprostane in the blood of rats after implantation of surgical meshes coated with tantalum and tantalum oxide. Materials and methods. The experimental group included 36 male rats of the WAG population weighing 240 ± 20 g. A 15x15 mm polypropylene surgical mesh was surgically implanted between the abdominal wall and various sections of the colon. Anesthesia was performed using the intraperitoneal route of administration of the drug «Relax» BioTestLab, Ukraine) at a dose of 8 mg/kg. After 28 days, the experimental animals were decapitated by cervical dislocation, and blood was immediately collected in sterile K2 EDTA VACUTAINER tubes (BD Vacutainer®). Blood samples were used to determine the content of 8-isoprostane in the blood by enzyme-linked immunosorbent assay using the «8-isoprostane EIA KIT» kit (Cayman Chemical Company, USA) according to the manufacturer’s instructions on the «Solar» PV-1251C spectrophotometer. Results and discussion. The content of 8-isoprostane in blood plasma was statistically 158,6 % higher in the experimental group implanted with uncoated surgical mesh and 171,5 % higher in the experimental group implanted with polypropylene surgical mesh with tantalum nitride coating in comparison with the results of the control group. The concentration of 8-isoprostane in the blood of rats after implantation of polypropylene surgical meshes with a coating based on tantalum and tantalum oxide was higher by 102,6 % and 111,1 %, respectively, compared to the results obtained in the group of intact animals, which indicates their better biocompatibility compared to the results of the groups implanted with uncoated and coated tantalum nitride surgical mesh. Conclusion. The obtained results indicate that coatings based on tantalum and tantalum oxide inhibit lipid peroxidation and demonstrate excellent biocompatibility and anti-inflammatory effect, which makes it possible to consider their future use in hernioplasty.
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Zenfira Huseynli, Ali Mansurov, Zenfira Huseynli, Ali Mansurov, and Gulshad Aghayeva, Rovshana Aliyeva Gulshad Aghayeva, Rovshana Aliyeva. "INCREASING THE PERFORMANCE OF CHRISTMAS TREES IN SANDY CONDITIONS." ETM - Equipment, Technologies, Materials 18, no. 06 (December 10, 2023): 108–14. http://dx.doi.org/10.36962/etm18062023-108.
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The key reason to make this research is to find solutions for mechanical impurities, or commonly sand clogging in christmas trees. As it’s known, christmas trees are equipment made for controlling flow of oil and gas, which consists of several gauges and valves for specific purposes. This equipment installed on wells are constantly clogged with various impurities. These mechanical consistency interrupt christmas tree’s work and cause wears and tears which leads to failure of system and overall oil production delay. Thus, frequent maintenance is required. There are two main ways to release the clogging in wells: mechanical and chemical. In this research, mechanical way is applied. To improve and increase the performance of christmas trees, various types of filters are considered with their advantages and disadvantages according to previous experiences. Studies show that, for different type of wells different type of filters, separators etc. are used. Filters used to prevent sand particles are gravel filter, slot filter, perforated filter, wire well filter, well mesh filter, frame-rod filter, slot filter, support element filters and other filters which are considered in this research. According to the mesh principle, the filters which are a component of the ESP - are intended to prevent sand particles from entering the production stream by holding big particles and filtering the resulting liquid. To choose a filter with the best permeation rate and to stop particles larger than a specific size from penetrating, the size of the channels must be calculated. Modification and other movable factors are used to separate each group of filters. Keywords: Christmas tree (oil and gas), mechanical impurities, sand, filter, oil well, separators.
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Thornton, Christine. "Towards a Group Analytic Praxis for Working with Teams in Organizations." Group Analysis 50, no. 4 (October 18, 2017): 519–36. http://dx.doi.org/10.1177/0533316417728348.
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Several aspects of group analysis render it a useful discipline for consulting to organizations and working with teams in complex post-modern environments. These include attention to the individual in the group, sophisticated grasp of the nuances of interpersonal communication, attention to context, tolerance and the value of multiple perspectives, creative incorporation of difference and a flexible developmental approach to managing anxiety and leadership projections. The importance assigned to context, and the value placed on multiple perspectives as holding elements of reality, mesh with systems and complexity theories so that group analysis offers a coherent intellectual framework for understanding interplaying processes in the system, from individual, through team, departmental and organizational, to societal and global levels. While several writers have demonstrated the value of group analytic thinking in understanding organizations, to date none have attempted to contextualize their perspective with those of others working in the field. This article opens with a literature review, articulates some core contextual differences between clinical and organizational work, and identifies the characteristics of group analysis that make it a valuable discipline in organizational work. A second companion article elaborates, setting out further differences in praxis in organizational rather than therapeutic work and discussing contracting for organizational work.
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Irianov, Yu M., and N. A. Kiryanov. "Bone Tissue Repair During Implantation of Titanium Nickelide Mesh: Scanning Electron Microscopy and X-Ray Electron Probe Microanalysis Observation." Journal of Tissue Repair and Regeneration 1, no. 1 (August 20, 2018): 28–36. http://dx.doi.org/10.14302/issn.2640-6403.jtrr-18-2158.
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Purpose of Study: To study reparative osteogenesis and tissue integration characteristics for implanting three-dimensional mesh structures of titanium nickelide into a bone cavitary defect. Material and Methods: The authors modeled cavitary defects of femoral metaphysis experimentally in Wistar rats divided into an experimental group and control one. The study duration was 60 days in total. The methods of radiography, those of light and electron microscopy, X-ray electron probe microanalysis used. Results: Under implantation the defect was filled with cancellous bone the volumetric density of which more than 1,5-fold exceeded control values (р < 0.001). The implant had biocompatibility, osteoconductive and osteoinductive properties, it stopped inflammatory processes. The membrane protective barrier which prevented connective tissue sprouting was formed on the implant surface in the defect periosteal zone. The osteointegrative junction was formed being persisted up to the end of the experiment. Reparative osteogenesis was performed by direct intramembranous and apposition type. Conclusion: The implant of three-dimensional mesh titanium-nickelide structures has marked osteoplastic properties, and it can be successfully used in orthopedic surgery.
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Vlase, Ene, Florica Barbuceanu, Danut Turcu, Mariana Coman, Marius Badulescu, Mariana Oporanu, Cristin Coman, and Carmen Surdu-Bob. "Copper Bead Therapy in Severe Bone Infection: A Rabbit Tibial Model." Veterinary and Comparative Orthopaedics and Traumatology 32, no. 01 (January 2019): 041–50. http://dx.doi.org/10.1055/s-0038-1676292.
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Abstract Objective We investigated the benefits of a local preventive therapy based on copper beads against severe bone infection using a rabbit open tibial fracture model. Materials and Methods Cotton mesh balls soaked in a very high concentration of Staphylococcus aureus ATCC 6538 culture were inoculated in drilled holes of the tibiae of treated and control groups. The treated group was also implanted with small copper beads simultaneously, as prevention therapy. Results Survival rate in the treated group was 67% compared with 25% in the control group (difference 40%, for a 95% confidence interval: 40%, 93.4%). The few remaining animals in the control group had bone lesions which developed into osteomyelitis, while the tibiae of treated group had clear signs of reparatory processes. Sixty days after inoculation, signs of local-only toxicity were observed in healthy tibia of a separate non-infected control group. Drawbacks of copper toxicity were weighed against the threat of septicaemia and also against prolonged use of powerful systemic antibiotic medications in severe bone contamination. Cinical Significance It was found that the proposed therapy prevented septicaemia and the spread of infection, and it also induced reparatory processes. The findings of this study may be relevant in antisepsis of open fractures in less appropriate medical settings (such as military camps or remote locations), as well as in severe bone infections.
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Hidayat, Sahrul, Ibnu Mubarok, Budi Adiperdana, Bambang Joko Suroto, Nowo Riveli, Yeni Wahyuni Hartati, and Iman Rahayu. "Characteristics of CMC from Corncob and its Application as Electrode Binder in Lithium Ion Battery." Materials Science Forum 966 (August 2019): 433–36. http://dx.doi.org/10.4028/www.scientific.net/msf.966.433.
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Corncobs are a waste product from corn farming that are abundant in Indonesia. Corncobs have a high cellulose content, more than 40%, which made it useful for synthesizing CMC. CMC is a cellulose derivative that is widely used in many industries such as food, pharmaceutical, detergent, textile, cosmetic product and binder. In this paper, we use CMC that are synthesized from corncobs as binder in the electrodes of lithium ion battery. The steps of synthesizing CMC from corncobs started with the isolation of the cellulose, then followed by the processes of alkalization, carboxymethylation and finally the purification. FTIR spectrum shows that CMC are successfully synthesized. The presence of strong absorption band at 1613 cm-1 is related to the stretching vibration of the carboxyl group (COO-). The absorption in the 1300–1450 cm-1 region is due to symmetrical deformations of CH2 groups. While the broad absorption around 3427 cm-1 is due to the stretching of the hydroxyl groups (-OH). Test on three samples of different sizes, (mesh-100, mesh-60 and mesh-40) gives CMC purity values of 98.69%, 98.56% and 97.77%, respectively. In the application of CMC as anode binder, the best composition is 4% CMC, where it gives the highest conductivity of 0.587 S/cm. Voltammogram measurement with a scan rate of 50 mV/s in the voltage range of -1 to 1 Volt gives the capacitance value of 2237 μF.
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Faur, Andrei B., Raul N. Rotar, Dragoș Adam, and Anca Jivănescu. "Rescanning of Digital Impressions’ Mesh Holes: In Vivo and In Vitro Accuracy Evaluation of Three Different Scanning Protocols." Applied Sciences 13, no. 5 (February 23, 2023): 2867. http://dx.doi.org/10.3390/app13052867.
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Several factors have been identified to have an influence over the accuracy of a digital impression: ambient lighting conditions, the presence of liquid on the intraoral structures, and the scanning patterns. The purpose of this study was to identify which protocol produced the most accurate digital impression regarding a one-preparation scenario in which data were acquired from a single uninterrupted scan, a rescanning of the area of interest in order to obtain more data, or the deletion of the area of interest followed by a rescan. An in vitro scenario using a typodont involving a single full-crown restoration was conceived alongside the selection of an in vivo case of a patient presenting an unrestored right mandibular first molar. The STL (standard tessellation language) reference models for each group were obtained using a high-resolution scanner (Freedom, HD; DOS). With the use of a Medit I700 (Medit, Seoul, South Korea) intraoral scanner, three different scanning protocols were conducted on the typodont and on the clinical case. The measured data (IOS scans) were sorted and further analyzed with the help of Geomagic Control X (Version:16.0.2.16496, 3D Systems, Wilsonville, OR, USA). The Kolmogorov–Smirnov test for normality was conducted on the whole set of data. The nonparametric data set underwent Kruskal–Wallis test analysis while the parametric data set underwent a one-way ANOVA test (the level of significance was set to α = 0.05). For the in vitro case, the “SINGLESCAN” group displayed the best trueness; the “DELETE&RESCAN” group displayed the best precision. Regarding the in vivo case, the “SINGLESCAN” group also displayed the best trueness; the “RESCAN” group displayed the best precision. Statistical differences were found in the trueness and precision of the IOS scans captured with the three different scanning protocols, but the differences were so small that they could be considered clinically negligible.
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Azimov, R. H., A. P. Vlasov, P. S. Glushkov, and V. A. Gorsky. "Reparative and functional state of postoperative wound tissues during hernioplasty with endoprosthesis "titanium silk" in patients with diabetes mellitus." Perm Medical Journal 39, no. 2 (May 10, 2022): 73–79. http://dx.doi.org/10.17816/pmj39273-79.
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Objective. To assess the reparative and functional state of the tissues of the postoperative wound during hernioplasty with the endoprosthesis "titanium silk" in patients with diabetes mellitus.
Materials and methods. Clinical and laboratory examination was carried out in 37 patients with inguinal hernias using the titanium silk endoprosthesis. The patients were divided into two groups. In the comparison group (n = 20), surgical treatment was performed in patients without diabetes mellitus, in the main group (n = 17), patients had type 1 or 2 diabetes mellitus. In the early postoperative period, the dynamics of healing process in the postoperative period was assessed using cytological and instrumental methods.
Results. It was found that inflammation and microcirculation disorders are observed in the tissues of the postoperative period. However, it was noted that when using the endoprosthesis "titanium silk" in patients of both the main and the control groups, no disruption of the reparative processes was detected.
Conclusions. The use of titanium mesh endoprostheses "titanium silk" for hernioplasty of inguinal hernias in patients with diabetes mellitus does not violate the fundamental processes of tissue healing in the region of the operation.
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Филатов, К. Ю., В. В. Воробьев, Д. С. Булучевский, В. Ф. Барабанов, and Н. И. Гребенникова. "THE STRUCTURE OF THE MICROCLIMATE REMOTE MONITORING SYSTEM BASED ON CELLULAR TOPOLOGY." ВЕСТНИК ВОРОНЕЖСКОГО ГОСУДАРСТВЕННОГО ТЕХНИЧЕСКОГО УНИВЕРСИТЕТА, no. 3 (June 28, 2023): 28–35. http://dx.doi.org/10.36622/vstu.2023.19.3.005.
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учитывая, что выбор оптимальной архитектуры беспроводной сети и ее параметров является сложной задачей, в данной статье рассматривается один из методов построения архитектуры ячеистой топологии, который предусматривает подключение к интернету устройств для обмена данными между собой и с другими системами, используя безопасные протоколы сетевой связи. Задача является актуальной, поскольку ее решение создает новые возможности для сбора и обработки данных, управления и автоматизации процессов, а также повышения удобства и комфорта жизни людей. Рассмотрено использование технологии беспроводных сетей. Проведено исследование с целью сравнения «классической» работы с датчиками в LAN и работы с использованием технологии MESH. Было создано приложение, работающее с мобильной группой узлов для отправки данных на агрегирующий их сервер, к которому будет подключаться нативное Android-приложение. В итоге проведенных исследований сделан вывод, что выбор между стандартным подключением датчиков к сети Wi-Fi и ячеистой топологией с использованием Mesh Wi-Fi зависит от конкретных потребностей и ограничений. Сравнение технологий беспроводных сетей проводилось по результатам работы приложения по мониторингу погодных условий. Данный проект позволит обеспечить бесперебойную работу приложения, позволяющего на базе сети Wi-Fi организовать систему мониторинга микроклимата заданных зон considering that choosing the optimal architecture of a wireless network and its parameters is an extremely difficult task, this article discusses one of the methods for constructing a cellular network architecture, which provides for connecting devices to the Internet to exchange data between themselves and with other systems using secure network communication protocols. The task is relevant because its solution creates new opportunities for data collection and processing, management and automation of processes, as well as improving the convenience and comfort of people's lives. The use of wireless network technology is considered. A study was conducted to compare the "classical" work with sensors in LAN and work using MESH technology. An application was created that works with a mobile group of nodes to send data to an aggregating server, to which a native Android application will connect. As a result of the conducted research, it was concluded that the choice between a standard connection of sensors to a Wi-Fi network and a mesh topology using Mesh Wi-Fi depends on specific needs and limitations. The comparison of wireless network technologies was carried out based on the results of the weather monitoring application. This project will ensure the uninterrupted operation of the application, which allows organizing a microclimate monitoring system based on a Wi-Fi network from specified zones
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Melnikov, R. V., and E. P. Bragar. "ASSESSMENT OF FEM CALCULATION RESULTS ACCURACY WITH THE USE OF SYMMETRY PLANES IN GEOTECHNICAL PROBLEMS." Construction and Geotechnics 11, no. 2 (December 15, 2020): 28–39. http://dx.doi.org/10.15593/2224-9826/2020.2.03.
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To calculate different geotechnical objects (foundations of unique buildings, pile foundation grillages, slab foundations, embankments, etc.) we often need to simplify geometric model. Use of symmetry principles allows to simplify the model without reducing its detail. A relevant issue with the use of symmetry planes is the assessment of calculation results accuracy. The article considers the research of such an assessment for two traditional geotechnical problems: a shallow foundation slab and a shoring of deep excavation. Calculations have been performed with various options of symmetry planes usage: a full-scale model, using one symmetry plane, using two symmetry planes; differences in the ways of representing building structures: 2D and 3D continuum elements. Generating the finite element mesh, we took into account the fact, that the degree of mesh grinding significantly influence the accuracy of the calculation results. That’s why the finite element mesh was divided into two areas: the area of «interest» represented by small sized elements, and the «peripheral» area created by larger elements. We also considered the sequence of technological processes: the initial stage of the calculation is the creation of the initial stress state, the next stage is the creation of the structure (foundation slab, shoring of excavation), the final stage is the force application. The calculation results were evaluated according to the criteria related to the second group of limit states. The controlled parameters for the shallow foundation slab were: maximum and average settlement, relative difference of settlements; for the shoring of deep excavation - the maximum displacement of the enclosure structure. It was found out that to present the construction in the form of 2D-elements it is necessary to introduce additional boundary conditions. They prevent rotation in nodes located on the plane of symmetry. The authors make conclusions and recommendations for creating design models with the use of symmetry planes.
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Safonov, R. A., O. S. Alekseieva, and V. V. Lazurenko. "TREATMENT TACTICS FOR GENITAL PROLAPSES IN WOMEN WITH ABNORMAL UTERINE BLEEDING AND THYROID GLAND PATHOLOGY." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 23, no. 1 (March 13, 2023): 69–72. http://dx.doi.org/10.31718/2077-1096.23.1.69.
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Introduction. Patients with genital prolapse have various extragenital pathologies, in particular thyroid pathology, which affects the regulation of the menstrual cycle both in the reproductive and perimenopausal periods of a woman's life. Abnormal uterine bleeding caused by hormonal disorders, functional and organic changes in the thyroid gland is reported as a common problem of perimenopausal age. The aim of this study is to optimize the treatment of genital prolapse in women with abnormal uterine bleeding and thyroid pathology. Materials and methods. 49 perimenopausal women with genital prolapse who had thyroid pathology were examined and treated. They were divided into the main group (29 women with abnormal uterine bleeding) and the comparison group of 20 patients with genital prolapse without abnormal uterine bleeding. 20 women without signs of gynaecological and extragenital pathology made up the control group. Results. The presence of significant deviations in the serum content of steroid hormones in women with thyroid dysfunction allows us to confirm the relationship between proliferative processes in the endometrium and the functioning of the thyroid system. The examination revealed a significant relationship between thyroid dysfunction and the cause of abnormal uterine bleeding. Depending on the treatment method, the women of the main group were divided into 2 subgroups: the first subgroup included 19 patients who underwent vaginal extirpation of the uterus and simultaneous correction of genital prolapse with additional sacrospinal fixation of the vaginal stump using a mesh implant fragment. 10 patients were included in the second subgroup, which underwent hysteroresectoscopy due to abnormal uterine bleeding, and surgical treatment of genital prolapse was performed after a certain period of time (after 0.5-3 years, on average after 21-24 months). In the comparison group, planned vaginal extirpation of the uterus was performed. Conclusion. The improvement of the treatment of genital prolapse in women with abnormal uterine bleeding and thyroid pathology consists in combining vaginal removal of the uterus followed by strengthening of the vaginal dome through the use of sacrospinal fixation and/or a mesh implant in order to prevent recurrences and improve the economic indicators of the medical institution and the quality of life of patients.
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Burns, J. H. R., D. Delparte, R. D. Gates, and M. Takabayashi. "UTILIZING UNDERWATER THREE-DIMENSIONAL MODELING TO ENHANCE ECOLOGICAL AND BIOLOGICAL STUDIES OF CORAL REEFS." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XL-5/W5 (April 9, 2015): 61–66. http://dx.doi.org/10.5194/isprsarchives-xl-5-w5-61-2015.
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The structural complexity of coral reefs profoundly affects the biodiversity, productivity, and overall functionality of reef ecosystems. Conventional survey techniques utilize 2-dimensional metrics that are inadequate for accurately capturing and quantifying the intricate structural complexity of scleractinian corals. A 3-dimensional (3D) approach improves the capacity to accurately measure architectural complexity, topography, rugosity, volume, and other structural characteristics that play a significant role in habitat facilitation and ecosystem processes. This study utilized Structure-from-Motion (SfM) photogrammetry techniques to create 3D mesh models for several Hawaiian corals that represent distinct morphological phenotypes. The orthophotos and digital elevation models generated from the SfM process were imported into geospatial analysis software in order to quantify several metrics pertaining to 3D complexity that are known to affect ecosystem biodiversity and productivity. The 3D structural properties of the reconstructed coral colonies were statistically analyzed to determine if the each species represents a unique morpho-functional group. The SfM reconstruction techniques described in this paper can be utilized for an array of research purposes to improve our understanding of how changes in coral composition affect habitat structure and ecological processes in coral reef ecosystems.
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Kudriavtsev, A. V., S. I. Savosko, V. P. Kryshen, and N. M. Nor. "THE EFFECT OF A POLYPROPYLENE IMPLANT TREATED WITH THYROTHRICIN ON THE HYPOGASTRIC TISSUES OF THE ABDOMINAL WALL IN RATS." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 24, no. 1 (March 20, 2024): 99–106. http://dx.doi.org/10.31718/2077-1096.24.1.99.
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Introduction. The study of tissue reactions to the placement of polymeric materials (polypropylene mesh), used for the treatment of hernias, remains relevant. The paper examines the hypothesis regarding the existence of certain differences in tissue reactions to polypropylene implants without and with treatment of the latter with an antimicrobial agent. Objective of this study is to investigate the reaction of the tissues of the peritoneum and the muscle-aponeurotic layer of the abdominal wall to a polypropylene implant treated with thyrothricin, used for the treatment of complicated variants of inguinal hernias.
Materials and methods. Experimental studies were conducted on laboratory sexually mature male Wistar rats. Experimental animals made up 4 groups of 5 animals each. The 1st group included control animals (intact). In the rats of the 2nd group, a defect of the abdominal wall of the hypogastric region was surgically modeled. In the animals of the 3rd experimental group, after modeling the defect of the abdominal wall, a polypropylene mesh implant was placed between the peritoneum and the inner leaf of the aponeurosis of the rectus abdominis muscles. The 4th experimental group consisted of animals in which the polypropylene implant was additionally treated with a thyrothricin solution.
Results. During the experimental study, the integration of tissue elements of the peritoneal walls and the muscle-aponeurotic layer of the abdominal wall with the material of polypropylene meshes was revealed. Active processes of collagenogenesis were observed in the boundary zones and the area of integration with the implant, as well as pronounced manifestations of vascularization of the newly formed connective tissue. The morphological features of the connective tissue formed in the area and around intact implants and meshes treated with thyrothricin did not significantly differ from each other, but significantly prevailed over the condition of the tissues in intact animals. No particular difference between the above-mentioned changes in the tissues of animals of the 3rd and 4th groups was found.
Conclusion. The obtained results indicate positive biocompatibility of body tissues and polypropylene implants. There is no negative effect of polypropylene nets treated with thyrothricin on body tissues and their regenerative potential.
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Palos-Barba, Viviana, Cecilia Lugo-Nabor, Rodrigo R. Velázquez-Castillo, Dora Alicia Solís-Casados, Carmen L. Peza-Ledesma, Eric M. Rivera-Muñoz, Rufino Nava, and Barbara Pawelec. "Development of an Adsorbing System Made of DMS-1 Mesh Modified by Amino Groups to Remove Pb(II) Ions from Water." Materials 13, no. 8 (April 18, 2020): 1914. http://dx.doi.org/10.3390/ma13081914.
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Water pollution by heavy metals represents several health risks. Conventional technologies employed to eliminate lead ions from residual or drinking water are expensive, therefore an efficient and low-cost technique is required and adsorption processes are a good alternative. In this work, the goal was to determine the adsorption capacity of a Disordered Mesoporous Silica 1 material (DMS-1) functionalized with amino groups, for Pb(II) ions removal. DMS-1 was prepared by sol-gel method and the incorporation of amino groups was performed by ex-situ method. As the source of amine groups, (3-Aminopropyl) triethoxysilane (APTES) was used and three different xNH2/DMS-1 molar ratios (0.2, 0.3, 0.4) were evaluated. In order to evaluate the incorporation of the amino group into the mesopore channels, thermal and structural analysis were made through Thermogravimetric Analysis (TGA), nitrogen adsorption–desorption at 77 K by Specific Brunauer–Emmett–Teller (SBET) method, Fourier Transfer Infrared spectroscopy (FTIR), Scanning Electron Microscopy (SEM), X-Ray Diffraction (XRD) and X-Ray Photoelectron Spectroscopy (XPS). The higher Pb(II) ions removal was achieved with the 0.3 molar proportion of xNH2/DMS-1 reaching 99.44% efficiency. This result suggests that the functionalized material can be used as an efficient adsorbent for Pb(II) ions from aqueous solution.
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Lukoyanychev, E. E., S. G. Izmailov, D. A. Evsyukov, V. O. Nikolskij, A. A. Mironov, and A. V. Panyushkin. "Possibilities of regulating the reaction of tissues of the implantation area with pyrimidine preparations after prosthetic repair of the hernia ring in the experiment." Research and Practical Medicine Journal 9, no. 4 (December 1, 2022): 83–95. http://dx.doi.org/10.17709/2410-1893-2022-9-4-8.
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Purpose of the study. Study of the possibilities of pharmacological regulation of local and systemic inflammatory response, stimulation of reparative regeneration in prosthetic repair of abdominal wall hernias.Materials and methods. The experiment was carried out on 92 rats of both sexes of a pure line, divided into 4 groups. Group I (control) received only 1 ml of 0.9 % sodium chloride solution. Group II – hydroxyethyldimethyldihydropyrimidine 21 mg/day. Group III – potassium orotate 10.5 mg/day. Group IV – methyluracil 14 mg/day. Under anesthesia a mesh implant 4 × 2 cm was placed in the layer between the hypodermis and the superficial fascia. Animals were withdrawn from the experiment on days 5 (n = 52) and 14 days (n = 40). The site of implantation for histomorphometric studies captured the dermis, hypodermis, implant layer, fascia, and muscle. The preparation and staining of the preparations were carried out with hematoxylin-eosin and by Mallory.Results. 1. On the 5th day after the operation group II (hydroxyethyldimethyldihydropyrimidine) was characterized by pronounced neovasculogenesis (p = 0.002, U-test) and more active processes of formation and maturation of connective tissue (p = 0.024, U-test) with a low immune response to a foreign body (p = 0.044, U- test). III (potassium orotate) and IV groups (methyluracil) were characterized by a pronounced decrease in the inflammatory response with a simultaneous increase in tissue edema (p < 0.001, U-test), slowing down the formation and maturation of connective tissue (p = 0.016, U-test). 2. On the 14th day after the operation, group II (hydroxyethyldimethyldihydropyrimidine) was characterized an increase in the area of neovasculogenesis by 208.0 % (p < 0.001, U -criterion), a decrease in the volume of fluid accumulations by 63.4 % (p < 0.001, U-criterion), an increase in the processes of formation and maturation of connective tissue, mainly due to an increase in the number of fibrocytes by 333.3 % (p < 0.001, U-criterion). The parameters of the immune response to a foreign body had significant differences (p < 0.001, U-test).Conclusion. The use of potassium orotate and methyluracil reduces the inflammatory response in the tissues of the implantation area, however, it is associated with the appearance of liquid components and with a decrease in the formation of connective tissue cells. The use of hydroxyethyldimethyldihydropyrimidine is devoid of the above disadvantages, it is characterized by the predominance of regeneration and neovasculogenesis processes, which allows it to be used as a pharmacological support drug for prosthetic hernioplasty.
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Nakonechna, O. A., R. M. Smachylo, S. V. Dudin, and O. V. Kyslov. "ГЕНЕРАЦІЯ АКТИВНИХ ФОРМ КИСНЮ ЛЕЙКОЦИТАМИ КРОВІ ЩУРІВ ПІСЛЯ ІМПЛАНТАЦІЇ ХІРУРГІЧНОЇ СІТКИ З ПОКРИТТЯМ НА ОСНОВІ ТАНТАЛУ." Medical and Clinical Chemistry, no. 1 (April 29, 2024): 5–10. http://dx.doi.org/10.11603/mcch.2410-681x.2024.i1.14591.
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Introduction. Over the past 20 years, polypropylene has become the main material used in hernioplasty, and has proven itself as an excellent material for the restoration of the abdominal wall during hernia repair. Since polypropylene surgical meshes do not decompose well in the body, they can stimulate the development of an inflammatory process in the surrounding tissues, which subsequently causes adhesions. The development of a postoperative inflammatory process after implantation of polypropylene surgical meshes is observed in 30–40 % of patients. This affects the management of the postoperative period, increases the time of stay of patients in the hospital and their period of convalescence. These data force scientists to continue the search for the optimal surgical mesh, which would suit specialists not only from the side of the physical properties of the surgical mesh, but also from the side of its biocompatible and anti-inflammatory properties. Tantalum is successfully used to produce biocompatible medical implants in surgery, orthopedics and dentistry. In previous studies, we have repeatedly noted its excellent anti-inflammatory and antibacterial properties, indicating the possibility of its use as a coating for mesh implants. One of the typical responses to surgical intervention is the generation of reactive oxygen species by leukocyte neutrophils, which are signaling molecules that damage the endothelium of vessels and promote the migration of cells of the immune system to the center of inflammation. The aim of the study – to determine the generation of reactive oxygen species in leukocytes of rats of the control group and experimental rats with implantation of uncoated and tantalum-based surgical meshes. Materials and Methods. ROS generation was assessed in rat blood leukocytes using the dye 2,7-dichlorodihydrofluorescein diacetate (H2DCFDA) by flow cytometry 28 days after implantation of uncoated and tantalum-coated surgical meshes. Results and Discussion. Analyzing the obtained results, it was determined that the use of tantalum-based surgical meshes does not cause excessive generation of ROS by leukocytes, in contrast to the use of an implant without a coating. Implantation of uncoated surgical mesh caused excessive production of reactive oxygen species in blood leukocytes of rats, as evidenced by statistically significant differences in the mean fluorescence intensity of 2,7- dichlorodihydrofluorescein diacetate. Conclusions. The use of tantalum-based surgical meshes causes less generation of ROS in leukocytes compared to the use of uncoated surgical meshes, and does not provoke the development of adhesions and purulent-septic processes in the postoperative period, which is confirmed by a morphological study. This determines the possibility of their use in surgical practice to improve the durability and stability of use as biomedical implants and prevention of adhesion formation.
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Anisa Firdaus, Fidya, Reffi Nantia Khaerunnisa, and Heri Ariyanto. "The Effect Music Therapy on Quality of Sleep." Genius Journal 1, no. 1 (July 29, 2020): 23–31. http://dx.doi.org/10.56359/gj.v1i1.5.
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Background Music therapy is a non-pharmacological therapy that combines mind-body therapy as an intervention technique that shapes thinking processes so that it affects psychological and physical conditions (bodily functions). Objectives This study aims to evaluate the efficacy of music on sleep quality accompanied by sleep complaints with or without comorbid medical conditions. Data Sources We conducted data searches from Cochrane, PubMed, Willey Online Library, JSTOR, Sage Journal, Taylor Francis Online, Springer and Science Direct. Method This study uses the PIOS (Participants, interventions, outcomes, Study design) and Mesh methods in finding data. Results Fourteen randomized controlled trials with six treatment conditions and a total of 633 participants with 319 participants in the intervention group and 314 controls met our inclusion criteria. Music therapy has a moderate effect on sleep quality of patients with sleep complaints with an average difference of -0.44 (95% CI: -1.01 to 0.33). Conclusion Music therapy is an initiative that is easy to implement, practical, and inexpensive and has no side effects and can be done in nursing practice to treat sleep problems in various populations in Indonesia.
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Nguyen, Hung Quoc, and Canh-Dung Tran. "Simulation of non-dilute fibre suspensions using RBF-based macro–micro multiscale method." Korea-Australia Rheology Journal 34, no. 1 (February 2022): 1–15. http://dx.doi.org/10.1007/s13367-022-00022-1.
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AbstractThe multiscale stochastic simulation method based on the marriage of the Brownian Configuration Field (BCF) and the Radial Basis Function mesh-free approximation for dilute fibre suspensions by our group, is further developed to simulate non-dilute fibre suspensions. For the present approach, the macro and micro processes proceeded at each time step are linked to each other by a fibre contributed stress formula associated with the used kinetic model. Due to the feature of non-dilute fibre suspensions, the interaction between fibres is introduced into the evolution equation to determine fibre configurations using the BCF method. The fibre stresses are then determined based on the fibre configuration fields using the Phan–Thien–Graham model. The efficiency of the simulation method is demonstrated by the analysis of the two challenging problems, the axisymmetric contraction and expansion flows, for a range of the fibre concentration from semi-dilute to concentrated regimes. Results evidenced by numerical experiments show that the present method would be potential in analysing and simulating various suspensions in food and medical industries.
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Luksha, O. V., N. P. Krut’ko, and V. M. Chernetskaya. "Rheological properties and group chemical composition of oxidized bitumen in the presence of fibrous materials of various structures." Proceedings of the National Academy of Sciences of Belarus, Chemical Series 59, no. 2 (June 5, 2023): 162–68. http://dx.doi.org/10.29235/1561-8331-2023-59-2-162-168.
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The rheological properties of oxidized bitumen in the presence of fibrous materials based on cellulose and chrysotile asbestos used as stabilizing additives in the production of crushed stone-mastic asphalt concrete mixtures have been studied. It has been established that the supramolecular structure of fibers characterizing the interaction between macromolecules largely determines the effectiveness of their structuring action for oxidized bitumen. Thus, the introduction of cellulose fiber leads to an increase in the ability of the bitumen colloidal structure to the simultaneous occurrence of elastic and plastic components of deformation. This is due to the uniform distribution of the fiber in the dispersion medium of bitumen due to the penetration of hydrocarbon components of bitumen into the interfibrillary space of cellulose and the rupture of hydrogen bonds between hydroxyl groups. Тhe presence of strong structural bonds between chrysotile-asbestos macromolecules prevents the formation of strong reinforcing mesh in bitumen oils. As a result, the values of the structural and rheological parameters Pk1, Pk2 and Pm of the bitumen/chrysotile-asbestos composition are 1.5–2 times lower compared to the values for the bitumen/cellulose composition. The results of the study of the group composition and structural-rheological properties of bitumen compositions after heating at T = 163 °C indicate a higher stability of the bitumen-cellulose structure to the processes of thermal oxidative degradation compared to the structure formed in the bitumen/chrysotile-asbestos composition. By the method of thin-layer chromatography, it was found that the concentration of oils in the bitumen/chrysotile-asbestos composition is higher as compared to the bitumen/cellulose composition, indicating that the weakening of rheological properties and thermal stability in the presence of chrysotile-asbestos is not related to the microstructure of its fibers, which, according to some researchers, is prone to selective diffusion of oils into the capillaries of fibrils.
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Lazukina, Mariia V., Anna A. Mikhelson, N. V. Bashmakova, O. A. Melkozerova, G. N. Chistyakova, and Anastasiia A. Grishkina. "Influence of preoperative preparation on the vaginal architectonics of postmenopausal women with severe genital prolapse." Gynecology 22, no. 4 (September 10, 2020): 33–38. http://dx.doi.org/10.26442/20795696.2020.4.200155.
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Patients with severe postmenopausal genital prolapse (GP) are the most clinically difficult group of women, in which surgical treatment with mesh implants presents significant difficulties due to the duration of lesions amid pronounced structural changes in the tissues of the urogenital tract under conditions of hormone deficiency. That is why it is of particular importance to study the histological characteristics of the vaginal mucosa in women with GP, who must conduct surgical treatment of vaginal access.
Aim. To study the histological features of the vaginal mucosa in postmenopausal women with severe GP in preparation for surgical treatment with vaginal access.
Materials and methods. The study involved 70 postmenopausal women suffering from GP of stage III, IV in combination with genitourinary menopausal syndrome. Patients were randomized blindly into two groups. The therapy was carried out using vaginal forms of estrogen and progesterone preparations in combination with lactobacilli. In the comparison group, preoperative preparation was not performed. All patients underwent clinical and laboratory examination: general examination and gynecological examination, morphological examination of biopsy samples of the mucous membrane of the anterior vaginal wall, which were obtained during subsequent surgical treatment of GP. Methods of parametric statistics were used.
Results. It was established that focal dystrophy, acanthotic severity, keratinization of the vaginal epithelium, moderate inflammation are characteristic morphological changes in the vaginal mucosa in women with postmenopausal GP. Application at the stage of preparation for surgical treatment using vaginal forms, as a result of which estrogen and progesterone enhance the inflammatory process in the ulcerative vagina, reduce dystrophic changes and their severity in relation to complex changes and differentiation of the vaginal epithelium and activation of regeneration processes in tissues.
Conclusion. Reducing inflammation and the severity of dystrophic processes in vaginal enemas at the stage of preoperative preparation of women with postmenopausal GP favorably affects the regeneration processes, which in the first place can improve the outcome of surgical treatment.
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Savenkov, Y. F., M. V. Moiseienko, I. V. Korpusenko, and P. E. Bakulin. "MINI-INVASIVE THORACOPLASTY IN THE SURGICAL TREATMENT OF DESTRUCTIVE PULMONARY TUBERCULOSIS." Ukrainian Pulmonology Journal 31, no. 4 (2023): 31–34. http://dx.doi.org/10.31215/2306-4927-2023-31-4-31-34.
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Aim: to evaluate results of application of the developed technique of minimally invasive extrapleural thoracoplasty in the surgical treatment of patients with destructive pulmonary tuberculosis. Object and methods. Minimally invasive thoracoplasty was performed in 15 patients (study group): men made up 100 %, in the age range from 26 to 58 years. Chronic forms of pulmonary tuberculosis were diagnosed in 10 (66.6 %) patients, newly diagnosed tuberculosis in 5 (33.4 %). Multidrugresistant tuberculosis was observed in 78 % of patients. Bacterial excretion was observed in 86 % of patients. The size of the cavity in the lung did not exceed 6 cm. All patients in the pre- and postoperative periods received chemotherapy regimens based on the prescription of the CMAC / CRTB treatment regimen. The following effectiveness criteria were assessed: cessation of bacterial excretion 1 month after surgery (negative Bactec culture); closure of the destructive cavity confirmed on chest CT scan, the number of postoperative complications and the presence of relapses in the postoperative period. A new method of minimally invasive thoracoplasty was developed to improve the method of collapse-surgical treatment of patients with destructive pulmonary tuberculosis. It uses a resection of small segments of ribs, both in length and in number, extrapleural apicolysis and mediastinal pneumolysis, fixation of the lowered apex of the lung with polypropylene mesh, sealing the created extrapleural cavity with collagen to achieve adequate collapse of the lung in the cavernous zone and accelerate reparative pericavitary processes. The results. 15 patients were operated on according to this technique. Postoperative complications were observed in 1 (6.6 %) patient. Cessation of bacterial excretion after 1 month of treatment was registered in 100 % of patients, closure of the cavity after 2 months of treatment was achieved in 14 (93.3 %) patients. Key words: minimally invasive thoracoplasty, destructive pulmonary tuberculosis, polypropylene mesh, collagen plates.
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Kaiser, Michael G., Praveen V. Mummaneni, Paul G. Matz, Paul A. Anderson, Michael W. Groff, Robert F. Heary, Langston T. Holly, et al. "Radiographic assessment of cervical subaxial fusion." Journal of Neurosurgery: Spine 11, no. 2 (August 2009): 221–27. http://dx.doi.org/10.3171/2009.3.spine08719.
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Object The objective of this systematic review was to use evidence-based medicine to identify the best methodology for radiographic assessment of cervical subaxial fusion. Methods The National Library of Medicine and Cochrane Database were queried using MeSH headings and keywords relevant to cervical fusion. Abstracts were reviewed and studies meeting inclusion criteria were selected. The guidelines group assembled an evidentiary table summarizing the quality of evidence (Classes I–III). Disagreements regarding the level of evidence were resolved through an expert consensus conference. The group formulated recommendations that contained the degree of strength based on the Scottish Intercollegiate Guidelines network. Validation was done through peer review by the Joint Guidelines Committee of the American Association of Neurological Surgeons/Congress of Neurological Surgeons. Results Pseudarthrosis is best assessed through the absence of motion detected between the spinous processes on dynamic radiographs (Class II). The measurement of interspinous distance on dynamic radiographs of ≥ 2 mm is a more reliable indicator for pseudarthrosis than angular motion of 2° based on Cobb angle measurements (Class II). Similarly, it is also understood that the pseudarthrosis rate will increase as the threshold for allowable motion on dynamic radiographs decreases. The combination of interspinous distance measurements and identification of bone trabeculation is unreliable when performed by the treating surgeon (Class II). Identification of bone trabeculation on static radiographs should be considered a less reliable indicator of cervical arthrodesis than dynamic films (Class III). Conclusions Consideration should be given to dynamic radiographs and interspinous distance when assessing for pseudarthrosis.
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Xu, Xunqian, Tongxin Wu, Guangyao Qian, Fengyi Kang, Ganhouegnon Eric Patrick, and Wenkang Shi. "Numerical Modeling of Quasi-Brittle Materials Using a Phase-Field Regularized Cohesive Zone Model with Optimal Softening Law." Applied Sciences 12, no. 23 (November 25, 2022): 12077. http://dx.doi.org/10.3390/app122312077.
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In this paper, we propose an approach combining optimal softening laws and a phase-field regularized cohesive zone model (PF-CZM) for modeling the fracture and damage properties of quasi-brittle materials accurately. In this method, the optimal softening law is determined by comparing the predicted results with experimental data in the framework of the PF-CZM; three typical softening laws are considered. The PF-CZM with a length scale is used to model crack initiation and propagation without considering the mesh bias. We first investigate the mechanical responses and crack propagations of different concrete beams based on the above approach; the predicted results are compared with the data from conventional methods and experiments. The results indicate that the mechanical properties of concrete beams with the optimal softening law are better than the data reported in the literature. Further validation indicates that once the optimal softening law is determined, it is stable for the same group of materials. Moreover, we demonstrate that the PF-CZM can naturally predict and reproduce the critical notch offset and fracture transition process of three-point bending concrete beams and the fracture features of typical double-notched concrete beams, such as the interaction between two notches objectively, together with the changes of limit load capacity.
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Ruzmetova, Nodira, and Jungyin Kim. ""The Academic Socialization Process of International Students in South Korea: The Role of Culture in Group Activities"." Modern Studies in English Language & Literature 64, no. 3 (August 31, 2020): 139–69. http://dx.doi.org/10.17754/mesk.63.3.139.
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Leonardi, Rosalia, Simone Muraglie, Orazio Bennici, Costanza Cavallini, and Concetto Spampinato. "Three-dimensional analysis of mandibular functional units in adult patients with unilateral posterior crossbite: A cone beam study with the use of mirroring and surface-to-surface matching techniques." Angle Orthodontist 89, no. 4 (April 23, 2019): 590–96. http://dx.doi.org/10.2319/081718-607.1.
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ABSTRACT Objectives: To use three-dimensional (3D) mirroring and surface-to-surface techniques to determine any differences in mandibular functional unit shape and morphology between the crossbite side and non-crossbite side in adult patients with posterior unilateral crossbite who had not received any corrective treatment for malocclusion. Materials and Methods: Cone-beam computed tomography (CBCT) records from 24 consecutive adult white patients (mean age, 27.5 years; range 22.6–39.7 years; 14 women and 10 men) seeking treatment for maxillary transverse deficiency were assessed in this study. The control group comprised CBCT scans from age- and sex-matched patients. Segmentation masks were generated to obtain 3D surface mesh models of the mandibles and analyze the six skeletal functional units, which were further analyzed with reverse engineering software. Results: Statistically significant differences in the mean surface distance when comparing the study sample and the control sample were found at the condylar process, mandibular ramus, angular process (P ≤ .0001), and alveolar process (P ≤ .01); no statistically significant differences were found for the coronoid process, the chin, and the mandibular body (P ≥ .5). Conclusions: The condylar, angular, and alveolar processes plus the mandibular ramus appear to play a more dominant role than did the body, the coronoid, and the chin units in the asymmetry of the mandible in patients with unilateral crossbite.
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King, Dustin, and Natalie Strynadka. "Analysis of bacterial cell-wall synthesis to combat antibiotic resistance." Acta Crystallographica Section A Foundations and Advances 70, a1 (August 5, 2014): C701. http://dx.doi.org/10.1107/s2053273314092985.
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The peptidoglycan biosynthetic pathway is one of the most important processes in the bacterial cell to be exploited as a target for the design of antimicrobial drugs to combat infection and pathogenesis. This pathway, unique to bacteria, utilizes over twenty enzymes, likely in concert, with reactions that proceed from the cytoplasm, across the membrane and into the periplasmic space culminating in the production of the mesh-like structure composed of polymerized glycan and cross-linked peptide components that form the major structural component of the essential bacterial protective barrier known as the cell wall. Work in our group has aimed at understanding the structural and kinetic properties of several of these enzymes including the glycosyltransferase/transpeptidase activity of a family of enzymes known historically as the penicillin binding proteins (PBPs). As the name implies, these enzymes are also the target of beta-lactam antibiotics, and molecular modifications to transpeptidase variants have been shown to be linked to increased antibiotic resistance in superbugs such as Methicillin Resistant Staphlococcal aureus (MRSA). In parallel, highly disseminated plasmid-encoded beta-lactamase enzymes, with structural and mechanistic ties to the transpeptidases, have also arisen in many of the clinically important bacterial pathogens, leading to further widespread beta-lactam antibiotic resistance. The molecular details of these critical enzymatic reactions in bacterial viability and drug resistance will be presented.
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Degovtsov, E. N., P. V. Kolyadko, V. P. Kolyadko, and A. V. Satinov. "First Results of a Randomized Controlled Trial of Hemoblock in Patients with Large Incisional Hernias." Russian Sklifosovsky Journal "Emergency Medical Care" 8, no. 4 (January 17, 2020): 430–36. http://dx.doi.org/10.23934/2223-9022-2019-8-4-430-436.
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ABSTRACT. When penetrating into the cell, local anesthetics affect some structures and processes, in addition to blocking sodium channels, leading to the development of cell damage. The aim of the article was to study the damaging effect of bupivacaine on the sciatic nerve and biceps femoris in rats.AIM OF STUDY. Analysis of the first results of a randomized clinical trial (RCT) for the use of Hemoblock in patients with large incisional hernias and postoperative ultrasound (US) monitoring.OBJECTIVES. Improving the results of surgical treatment of patients with large incisional hernias.MATERIAL AND METHODS. Design of a simple blind randomized controlled trial with a 90 percent study power, α-error equal to 0.05 and β-error equal to 0.10. For this purpose, the total number of subjects is planned to be 66. Currently, there are 18 patients in the study, 10 in the comparison group (B), and 8 in the main group (A). Surgery is plastic prosthetic mesh implant in the sublay retromuscular position. We applied Hemoblock 15 ml retromuscularly and 15 ml subcutaneousely in group B. Wounds were drained by vacuum suction drains. Postoperatively — monitoring of a wounds by ultrasound examination on day 3, 7, 10, 12, 15, 18, and 21 after the removal of drains. The average age was 58.5±6.3 in group B and 55.6±11.7 years in group A (U=36.5, p>0.05), BMI 33.6±3.44 and 32.2±5.19 kg/m2 respectively (U=35, p>0.05), the width of the hernia defect was 11±1.7 cm and 11.1±1.0 (U=33, р>0.05), length 13.6±2.7 cm and 12.5±3.3 cm (U=29.5, p>0.05), the area was 118±22.7 cm2 and 108.1±24.1 cm2 respectively (U=28.5, p>0.05). The average ASA was 2.2 in group B and 2.0 in group A.RESULTS AND DISCUSSION. Median of follow-up for all patients was 30 days. Significant differences obtained in the duration of postoperative wound drainage — 4.2±0.9 days in group B versus 2.5±0.5 days in group A (U=4, p<0.01). In patients of group A, the amount of discharge by drainage and the level of CRP and albumin were lower. On ultrasound examination of the postoperative wound, starting from the 10th day, a significantly smaller volume of fluid accumulations was revealed in patients of this group, and from the 15th day fluid accumulations were not detected. In group B, one patient had seroma IIIc (according to MoralesCondo, 2012), 8 patients had IVa seroma, and one patient had IVb seroma spontaneously opened through the postoperative wound, which required debridement of the cavity on an outpatient for 21 days. In group A, only 3 patients had IVa seroma. The number of punctures was 23 in group B, and 3 in group A (χ2 =8.654, p=0.04, Fisher’s exact two-sided test (F) =0.00654, p<0.05). Hospital stay was 8.9±0.6 days in group B and 8.0±0.5 days in group A (U=11.5, p<0.05).CONCLUSION. According to preliminary data using local haemostatic agent Hemoblock allows: 1) to reduce the duration of postoperative wound drainage, 2) to reveal the period of inflammatory exudative processes in the postoperative wound, 3) to reduce the number of puncture interventions after incisional hernia repair, 4) to reduce the severity of pain and the need for analgesics, 5) to reduce the hospital stay time.Authors declare lack of the conflicts of interests.
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Dychok-Niedzielska, A. Z., and Y. V. Lesyk. "Influence of sulfur complex on hematological indicators of the rabits." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 20, no. 92 (December 10, 2018): 203–8. http://dx.doi.org/10.32718/nvlvet9242.
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The article presents results on the influence of different amounts of sulfur citrate, manufactured using nanotechnology and sodium sulfate in rabbit diet from 60 to 118 days of age on the hematological parameters of their organism. Studies have been conducted on 30 rabbits of the Hyla hybrid divided into six groups (control and five experimental), 6 animals in each. Animals were kept in regulated microclimate and illumination in mesh cages of 50×120×30 cm. Controlled rabbits fed without restriction a balanced granulated feed with free access to water. The young of the first (E-II), the second (E-II), the third (E-III) and the fourth (E-IV) experimental groups feed the diet of the control group and, during the day, dispensed sulfur citrate from the calculation of 2; 4; 8 and 12 mg S/kg body weight. Rabbits (E-V) of the experimental group fed the diet of the control group and set water with sodium sulfate (Na2SO4) in the amount of 40 mg S/kg body weight. In the preparatory period – 60 days and in the experimental period – at 91 and 118 days of life (31 and 58 days of delivery of supplements), blood samples were collected from the regional anterior vein of rabbits for hematological studies performed using an automatic hematologic analyzer (Orphee Mythic-18, Switzerland). Researches have shown that the administration of citrate sulfur in the amount of 8 mg S/kg of body weight was marked by a greater number of red blood cells and leukocytes, respectively, by 13.4 and 23.3% (P < 0.05) and with a higher level of HCT at 16.2% (P < 0.05), MCH, RDV and MCHC, respectively, 11.1; 14.5 and 2.6% (P < 0.05) on day 58 of the experiment compared with the control group. In the blood of animals in the 2nd experimental group, a higher concentration of hemoglobin (Р < 0.05) was observed at 31 days and a higher HCT (Р < 0.05) level was 58 days compared to control. Thus, the results of the study of the hematological parameters of the body of rabbits indicate their positive changes in the actions of the physiologically substantiated amount of organic sulfur, which contributed to the activation of metabolic processes.
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Kravtsov, O. V. "EARLY SURGICAL TREATMENT OF DEEP CIRCULAR BURNS WITH COMPARTMENT OCCURRENCE — SYNDROME BASED ON OBJECTIVES OF INTRA-TISSUE PRESSURE." Kharkiv Surgical School, no. 6 (December 30, 2023): 41–46. http://dx.doi.org/10.37699/2308-7005.6.2023.09.
Full textAbstract:
Abstract. Introduction. The frequency of burns increases especially during war, when not only the military, but also the civilian population is involved in hostilities. Compartment syndrome is a serious complication of deep circular burns and causes an increase in subfascial pressure and local tissue ischemia with the development of intercellular interstitial edema, which increases the disruption of tissue blood supply, which, in turn, increases the hypoxic state of tissues. Timely and effective diagnosis of compartment syndrome and early surgical treatment help to reduce intratissue pressure and reduce the scale of necrobiotic processes in damaged tissues. The purpose of the work improvement in the clinic of optimal variants of surgical tactics for the elimination of compartment syndrome occurrence in circular deep burns based on the study of the dynamics of intratissue pressure indicators. Materials and methods. The research used the results of treatment of 12 victims with deep circular burns who were hospitalized in the Kharkiv Burn Center in the period from 2022 to 2023. All patients were divided into the main and comparison groups. Patients of both groups were measured intratissue pressure in dynamics using the system Kompartmentdruck Monitor System фірми MIPM Mammendorfer Institut für Physik und Medizin Gmbh (Germany). Research results. The difference between the performed necrofasciotomy and primary necroctomy in the main group was (8±1) mm Hg. due to more radical decompression of thermally damaged tissues. The advantage of the proposed surgical treatment of victims with thermal injury was the possibility of earlier performance of free autodermoplasty with mesh grafts in patients of the main group already by (7.3 ± 0.5) days compared to (11.6 ± 0.6) days in the comparison group. The terms of skin restoration in patients of the main group were (22.8 ± 1.2) days, and in the comparison group (28.6 ± 0.8) days, which made it possible to reduce the time of inpatient treatment from (34.5 ± 0.9) days in the comparison group to (27.5 ± 0.7) days in the main group. Conclusions. Thus, improving the early surgical treatment of victims with circular deep burns by performing necrofasciotomy and primary necroctomy within 18.6 hours of the patient’s admission to the burn unit allowed to objectively confirm the importance of reducing intratissue pressure as a factor that forms the secondary deepening of the burn wound. Prevention of the deepening of the burn wound made it possible to create optimal conditions for the formation of granulation tissue and autodermoplasty.
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Oliveira, Marcos André de, and Luiz Antonio Alcântara Pereira. "Effect of Surface Roughness on Aerodynamic Loads of Bluff Body in Vicinity of Smoothed Moving Wall." Applied Sciences 14, no. 7 (March 29, 2024): 2919. http://dx.doi.org/10.3390/app14072919.
Full textAbstract:
This paper contributes to a new Lagrangian vortex method for the statistical control of turbulence in two-dimensional flow configurations around a rough circular cylinder in ground effect when considering higher subcritical Reynolds numbers, namely 3 × 104 ≤ Re ≤ 2 × 105. A smoothed moving wall (active control technique) is used to include the blockage effect in association with the variation in cylinder surface roughness (passive control technique), characterizing a hybrid approach. In contrast with the previous approaches of our research group, the rough cylinder surface is here geometrically constructed, and a new momentum source term is introduced and calculated for the investigated problem. The methodology is structured by coupling the random Discrete Vortex Method, the Lagrangian Dynamic Roughness Model, and the Large Eddy Simulation with turbulence closure using the truncated Second-Order Velocity Structure Function model. This methodological option has the advantage of dispensing with the use of both a refined near-wall mesh and wall functions. The disadvantage of costly processing is readily solved with Open Multi-Processing. The results reveal that intermediate and high roughness values are most efficient for Reynolds numbers on the orders of 105 and 104, respectively. In employing a moving wall, the transition from the large-gap to the intermediate-gap regime is satisfactorily characterized. For the conditions studied with the hybrid technique, it was concluded that the effect of roughness is preponderant and acts to anticipate the characteristics of a lower gap-to-diameter ratio regime, especially with regard to intermittency.