Academic literature on the topic 'Guava Leaf Extract'
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Journal articles on the topic "Guava Leaf Extract"
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Ariani, Sri Retno Dwi, Endang Susilowati, Elfi Susanti VH, and Setiyani Setiyani. "ACTIVITY TEST OF GUAVA (Psidium guajava L.) LEAF METHANOL EXTRACT AS CONTRACEPTION ANTIFERTILITY TO WHITE MICE (Rattus norvegicus)." Indonesian Journal of Chemistry 8, no. 2 (2010): 264–70. http://dx.doi.org/10.22146/ijc.21632.
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The aim of this research is to know about if the guava (Psidium guajava L.) leaf methanol extract on 10.5 mg/mL and 21.0 mg/mL dossages indicate a positive test as contraception antifertility to white mice (Rattus norvegicus). The sample is guava leaf from Mungkid, Magelang Central of Java Indonesia. The animals experiment are the white mice on 140-300 g for female, 200-250 g for male and about 3 months of age in average. The steps of this research are : (1) preparing sample, i.e. washing, drying on to indirect sunlight and make the sample into powder, (2) isolation the guava leaf powder in soxhlet instrument with hexane, (3) evaporation the sample with rotary evaporator until guava leaf hexane extract produced, (4) maseration the sample with methanol, (5) evaporation the sample with rotary evaporator until guava leaf methanol extract produced, (6) conducting contraception antifertility activity test to guave leaf methanol extract on 10.5 mg/mL and 21.0 mg/mL dossages to mice white. The results of this research are guava leaf methanol extract on 10.5 mg/mL and 21.0 mg/mL dossages indicate a negative contraception antifertility test to white mice but in these dossages have indicated that an antiimplantation effect (the total natality of fetus is less than the total implantation site in mice white). Keywords: Guava leaf, contraseption antifertility, methanol extract, white mice, implantation
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Maneechai, Suthira, Thawanrat Siphim, Nattaya Srisawad, and Waraporn Sutthisa. "Chemical Composition and Antifungal Properties of Guava Leaf Extract (Psidium guajava L.) Against Pythium aphanidermatum, Chinese Kale Damping-Off Disease Pathogen." Trends in Sciences 21, no. 9 (2024): 8134. http://dx.doi.org/10.48048/tis.2024.8134.
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Damping-off disease represents a considerable hazard to the cultivation of Chinese kale (Brassica oleracea var. alboglabra), leading to seedling death and notable economic repercussions. This study explores the efficacy of guava leaf extracts, obtained through different extraction solvents, against Pythium aphanidermatum, a significant pathogen causing damping-off disease in Chinese kale (Pak Kha-naa) cultivation in Thailand. Guava leaf extract was obtained using different solvents: hexane, ethyl acetate and ethanol. Subsequently, the extract was diluted to concentrations of 1,000, 1,500 and 3,000 ppm to assessment the inhibitory effects on P. aphanidermatum utilizing the poisoned plate technique. Results revealed that only ethanol-extracted guava leaf extract at 3,000 ppm exhibited significant inhibition of P. aphanidermatum, achieving complete inhibition. At 1,500 ppm, ethanol-extracted guava leaf extract demonstrated inhibition comparable to carbendazim. Greenhouse trials further confirmed the efficacy of pre-planting seeds coating with ethanolic guava leaf extract at concentrations of 1,500 and 3,000 ppm in reducing damping-off disease incidence in Chinese kale. Chemical analysis of guava extract with GC-MS revealed the presence of 58 compounds in the hexane extract, with copaene, β-caryophyllene, calamenene and caryophyllene oxide being major constituents. The ethyl acetate extract contained 53 compounds, including β-caryophyllene and squalene, while caryophyllene was a predominant component among the 40 chemicals identified in the ethanol extract. Methylparaben was exclusively present in the ethanol extract, showcasing inhibitory effects on the fungus. This research sheds light on the potential of guava leaf extracts as a sustainable solution for disease management in Chinese kale cultivation. HIGHLIGHTSEthanolic extract of guava leaf at 3,000 ppm completely inhibits the pathogen Pythium aphanidermatum. Seed coated with ethanol-extracted guava leaf extract at concentrations of 1,500 and 3,000 ppm reduced damping-off disease incidence in Chinese kale in greenhouse trials. Chemical analysis via GC-MS revealed diverse compounds in guava leaf extracts, with notable constituents such as copaene, β-caryophyllene, calamenene and caryophyllene oxide in the hexane extract, β-caryophyllene and squalene in the ethyl acetate extract and caryophyllene predominance in the ethanol extract. Identification of methylparaben exclusively in the ethanol extract suggests its potential inhibitory effects on the fungus. This study underscores the promising potential of guava leaf extracts as a sustainable solution for disease management in Chinese kale cultivation, offering insights into alternative methods for controlling damping-off disease. GRAPHICAL ABSTRACT
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Salah, M. El-Sayed, and M. Said Saadiya. "Antioxidant and Insecticidal Effect of Some Plant Extracts against Callosbruchus maculates (coleoptera: Bruchidae)." Chemistry Research Journal 2, no. 3 (2017): 133–43. https://doi.org/10.5281/zenodo.13955288.
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The aim of the study was to test the effect of methanolic guava leaf and pomegranate peel extracts as antioxidant and insecticide. In the Gas Chromatography and Mass spectroscopy analysis, 30 bioactive phytochemical compounds were identified in the methanolic extract of guava leaf and 23 bioactive phytochemical compounds were identified, in the methanolic extract of pomegranate peel. The fraction for guava leaf methanol extract was characterized by large amounts of caryophyllene , β- humulene and longifolene, which constituted 16.42% , 15.74% and 12.13% respectively , while the fraction of pomegranate peel methanol extract was characterized by large amounts of longifolene, alloaomadendrene and β- humulene which constituted 23.34% , 13.57% and 12.53% respectively .The phenolic contents of guava leaves and pomegranate peel extracts were found to be 154.16 and 280 (mg/g extract), respectively, while total flavonoids content were 55.45 and 69.24 (mg/g extract) respectively. Studies have confirmed that the antioxidant activity of plants extracts depends on the concentration of phenolic compounds, the methanolic extracts were assayed by DPPH scavenging activity and reducing power. Both methanolic guava leaf and pomegranate peel extracts appeared antioxidant activity in reducing power and DPPH scavenging activity assay, while the methanolic pomegranate peel extract was the more effective one compared with guava leaf extract. Insecticidal effects of these extracts on insect beetle cowpea were studied by determination LC50 which were 1.22 and 2.3 % for pomegranate peel and Guava leaves methanol extracts, respectively. The biochemical effects of these extracts were studied. Total protein, total carbohydrate and lipids increased but decreased acetylcholine esterase, GOT and GPT .The results showed that peels of pomegranate greatest influential extract and attributed this to the large content of phenols and Flavonoids.
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Lusiana, Nova, Risa Purnamasari, Indah Kurnia Sari, Jihan Farhah Huwaidah, and Eva Agustina. "Test The Potency Of Guava Leaf And Banyan Leaf Extract On Increasing Hemoglobin In Mice." Proceedings of International Conference on Halal Food and Health Nutrition 1, no. 1 (2023): 115–18. http://dx.doi.org/10.29080/ichafohn.v1i1.1117.
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Guava leaf plants (Psidium guajava) and banyan leaf plants (Ficus benjamina) contain compounds that include polyphenols, flavonoids, carotene, tannins, and iron which have the potential to increase hemoglobin levels and prevent anemia. Research has been carried out with the aim of observing the effect of banyan leaf extract and guava leaf extract on hemoglobin levels in the blood of mice. The administration of banyan leaf extract and guava leaf extract was carried out for 14 consecutive days in mice with the same dose of 300 mg/kg/day. The results showed that banyan leaf extract could increase hemoglobin levels by 40.36% while guava leaf extract increased by 45.79%. So it can be concluded that the administration of guava leaf extract and banyan leaf is proven to increase haemoglobin levels
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Fitria Firdhausi, Nirmala, Nova Lusiana, Risa Purnamasari, et al. "The Effect of Guava Leaf Extract (Psidium guajava) and Banyan Leaf (Ficus benjamina) on Glucose Levels in Mice (Mus musculus)." Proceedings of International Conference on Halal Food and Health Nutrition 1, no. 1 (2022): 28–31. http://dx.doi.org/10.29080/ichafohn.v1i1.1003.
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Guava leaves (Psidium guajava) and banyan leaves (Ficus benjamina) both contain tannins, flavonoids, carotene and iron. This study was conducted with the aim of knowing the effect of guava leaf extract and banyan leaf on glucose levels in the blood of mice. The study was conducted with an experimental method using Easy touch completely randomized with). Guava leaf extract and banyan leaf extract were administered for 14 consecutive days to mice at a dose of 300 mg/kg/day. The results showed that guava leaf and banyan leaf extract increased glucose levels in the blood of mice. guava leaf extract glucose by 4.52% and banyan leaves by 0.45%. So it can be said that offering guava leaf extract and banyan leaf extract with certain doses and treatments can increase glucose levels in test animals.
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Nurfitriyana, Nurfitriyana, Rini Yanuarti, and Indri Dyah Pangesti. "FORMULASI, EVALUASI DAN UJI ANTIBAKTERI SEDIAAN GEL EKSTRAK ETANOL DUAN JAMBU BIJI (Psidium guajava L.) SEBAGAI ANTI JERAWAT." ISTA Online Technologi Journal 2, no. 2 (2021): 50–59. http://dx.doi.org/10.62702/ion.v2i2.48.
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Acne is skin problems that can be overcome by using herbal plants, one of which is guava leaves. Guava leaves (Psidium guajava L.) contains tannins, saponins, polyphenols and flavonoids that can inhibit the growth of acne-causing bacteria. This study aims to formulate guava leaf extract (Psidium guajava L.) and evaluate the results of antibacterial tests on gel preparations as anti-acne. The ethanol extract was extracted and formulated using Na-CMC. Evaluation of the antibacterial activity of guava leaf extracts and preparations using Staphylococcus aureus and Eschericia coli bacteria. The results showed that the ethanol extract of guava leaves (Psidium guajava L.) with a concentration of 15% had antibacterial activity against Staphylococcus aureus with an inhibition area of 6.75 cm, and the gel preparation of guava leaf ethanol extract (Psidium guajava L.) resistance 0.2 mm. The evaluation found that the gel preparation of ethanol extract of guava leaves (Psidium guajava L.) can be used as an anti-acne gel.
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Maysarah, Hilda, Rika Apriani, and Misrahanum Misrahanum. "ANTIBACTERIAL ACTIVITY TEST OF ETHANOL EXTRACT OF WHITE AND RED FLESH FROM GUAVA LEAF ( Psidium guajava. L) AGAINTS Staphylococcus aureus AND Escherichia coli." Jurnal Natural 16, no. 1 (2016): 51–56. http://dx.doi.org/10.24815/jn.v16i1.4818.
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An antibacterial activity test of ethanol extract of white and red flesh from guava leaf (Psidium guajava. L) against S.aureus and E.coli; using agar diffusion method was carried out in order to produce the extract. The extract was collected using maceration method. The concentration of extract was 7,8125; 6,1035; 5,00; 4,8828; 4,3944; and 3,90625 mg/mL. The results showed that both of extracts had antibacterial activities. Ethanol extract of white flesh of fruit guava leaf had (Minimum Inhibitory Concentration) MIC value at 5.000 mg/mL against S.aureus and 4.8828 mg/mL against E.coli. Whereas ethanol extract of red flesh of fruit guava leaf had MIC value at 4.3944 mg/mL against S.aureus and E.coli. MIC value of ethanol extract of white flesh of fruit guava leaf is equal with MIC value of clindamicin concentration at 3.00 µg/mL against S.aureus, and 1.00 µg/mL against E.coli. The MIC value of red flesh of fruit guava leaf is equal to the MIC value of clindamicin concentration at 3.00 µg/mL against S.aureus, and 1.00 µg/mL against E.coli.
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Luo, You, Haiqing Liu, Shanzhong Yang, Jiarui Zeng, and Zhenqiang Wu. "Sodium Alginate-Based Green Packaging Films Functionalized by Guava Leaf Extracts and Their Bioactivities." Materials 12, no. 18 (2019): 2923. http://dx.doi.org/10.3390/ma12182923.
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The aim of this work was to develop green and bioactive films with sodium alginate incorporating guava leaf extracts. Seven formulations were performed with a different sodium alginate: Guava leaf water extract (WE)/ethanolic extract (EE) proportions (100:0, 90:10, 85:15, 80:20), and glycerol were used as a plasticizer. The HPLC-PDA analysis showed the main phenolic compounds in WE were gallic acid, ellagic acid, quercetin-3-O-β-D-xylopyranoside, avicularin and quercetin. The main polyphenols in EE were rutin, isoquercitrin, quercetin-3-O-β-D-xylopyranoside, avicularin, quercitrin, quercetin and kaempferol. Guava leaf extracts could greatly enhance the antioxidant activity, antibacterial activity, tensile strength and water solubility of the sodium alginate film as well as the water barrier property, while inducing a decrease in the moisture content and elongation at the break. The FTIR and SEM analyses indicated that intermolecular hydrogen bonding between the guava leaf extract and sodium alginate resulted in a more compact structure in the composite films. These results indicated that sodium alginate-guava leaf extract films might be developed into antiradical and antimicrobial food packaging materials.
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Pangestu, Andre, Khaira Nova, Dian Septinova, and RR Riyanti. "PENGARUH PENGGUNAAN EKSTRAK DAUN JAMBU BIJI (Psidium guajava L.) TERHADAP MORTALITAS EMBRIO, DAYA TETAS, DAN SALEABLE ITIK HIBRIDA." Jurnal Riset dan Inovasi Peternakan (Journal of Research and Innovation of Animals) 5, no. 2 (2021): 88–93. http://dx.doi.org/10.23960/jrip.2021.5.2.88-93.
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This study aimed to determine the effect of immersion of hybrid duck eggs using guava leaf extract at different concentrations on embryo mortality, hatchability, and saleable duck. The research was conducted in March - April 2020. Guava leaf extract was made at the Animal Production and Reproduction Laboratory, Department of Animal Husbandry, Faculty of Agriculture, University of Lampung. The dyeing and hatching treatments were carried out in Hajimena Village, Natar District, South Lampung. This study used a completely randomized design (CRD) with four treatments, namely without immersing guava leaf extract (P0), immersing with guava leaf extract concentrations of 10% (P1), 20% (P2), and 30% (P3). The results showed that the percentage of embryo mortality without dyeing and immersing guava leaf extract concentrations of 10, 20, and 30% were 40.00%, 24.00%, 16.00%, and 28.00%, respectively. Hatchability of hybrid duck eggs in the treatment without immersion and immersion in guava leaf extract concentrations of 10, 20, and 30% were 60.00, 76.00, 84.00, and 72%, respectively. Saleable duck duck eggs without immersion 93.34% and immersion in guava leaf extract with concentrations of 10, 20, and 30% respectively were 100.00%. It was concluded that immersion of hybrid duck eggs using guava leaf extract at concentrations of 10.00, 20.00, and 30.00% decreased the percentage of mortality, increased hatchability, and increased the salable duck. 
 
 Keywords: Hybrid duck, Guava leaves extract, Embryonic mortality, Hatchability, Saleable duck
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Haris, Fahni. "Jumlah Bakteri pada Luka Diabetik Kronik yang Dicuci Menggunakan Ekstrak Air Daun Jambu Biji (Psidium Guava)." Jurnal Ners dan Kebidanan Indonesia 5, no. 2 (2017): 106. http://dx.doi.org/10.21927/jnki.2017.5(2).106-114.
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<em>Various solutions have been recommended for cleanse the wound, however normal saline is favored. Aqueous guava leaf extracts have material that known for antibacterial in the diabetic wound care especially for cleansing. Guava leaf available in Indonesia, but there is unresolved debate about its use. This study use quasi-experimental with pre-test post-test design. Sample in this study consist 19 outpatients who had diabetic chronic wounds care in clinic Kitamura, Pontianak. Analysis of quantitative data was tested with non-parametric analysis, Wilcoxon test and Mann Whitney test to determine the effect of aqueous guava leaves extract in reducing bacterial. Results sowed that he number of bacteria colonies after cleansing the wound using aqueous guava leaves extract was decreased. P-value on first day until seventh day for 10% aqueous guava leaves was p=0.008 (p0.05), but 20% aqueous guava leaves extract most effective than 10% aqueous guava leaves extract.</em>
Dissertations / Theses on the topic "Guava Leaf Extract"
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Chang, Chia-Ting, and 張嘉婷. "Hypoglycemic Efficacy of Guava Leaf Extract." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/16212735523828387631.
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碩士<br>亞洲大學<br>保健營養生技學系碩士班<br>98<br>Abstract
Compendium of Materia Medica indicated that guava leaves may be used for treating subjects with diabetic conditions. Due to subtropical climate conditions, guava tree can be cultivated in large quantity throughout the year in Taiwan. We cooperated with guava framers and the farmer’s union at Shetou(社頭) District of Chunghwa County to study the blood glucose lowering potential of guava leaf by examining if guava leaf extract can inhibit protein tyrosine phosphatase-1B enzymatic activity.
Guava leaf was extracted with methanol extensively, and the extract was condensed for further partitioning. Solvents of different polarities were used in the serial partitioning; they include hexane, ethyl acetate, butanol and water. Guava leaf was also extracted directly with hot water, so a total of six fractions were obtained. These fractions were concentrated and tested for their effects on protein tyrosine phosphatase-1B (PTP-1B) enzymatic activity, which plays a major role at controlling insulin signaling and circulating blood glucose levels.
The water-soluble concentrate has an IC50 of 0.031 ±0.004 mg/mL when inhibiting protein tyrosine phosphatase-1B, while direct hot water extract has an of IC50 of 0.033 ±0.001 mg/mL, these two water soluble fractions are more potent than other fractions at inbiting PTP-1B enzyme activity in vitro.
Therefore, it is suggested that guava leaf tea can inhibit protein tyrosine phosphatase-1B activity, and the active ingredient be water-soluble.
Keywords: diabetic, guava leaf tea, protein tyrosine phosphatase-1B
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Chou, Hsuan-Ying, and 周玄盈. "Reductive degradation of carbon tetrachloride with guava leaf extract." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/11896633131950232897.
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碩士<br>國立中興大學<br>環境工程學系所<br>105<br>Chlorinated aliphatic hydrocarbons are common contaminants found in soil and groundwater. Carbon tetrachloride (CT), which has the highest carbon oxidation state, is prone to accept electrons and be dechlorinated. Polyphenols containing OH groups are rich in fruits (e.g., guava). Deprotonations of polyphenols when pH is greater than dissociation constant (pKa) of OH function group would cause electrons release. Therefore, polyphenols are regarded as natural antioxidants. This study attempted to extract polyphenols from guava leaves. Guava leaf extract (GLE) was prepared as solid powder and liquid filtrate forms, named GLE-Powder and GLE-Filtrate, respectively. Reductive degradation of CT with GLE was investigated and influences of parameters such as pH, temperature, the presence of soils, different iron minerals (FeS2, Fe2O3, Fe3O4 and FeOOH), Fe(II) and Fe(III) were assessed. Byproducts and pathways of CT degradation were also discussed. For characterization of GLE, total phenolic content, antioxidant activity, reducing power and ferrous ion-chelating ability were analyzed. It was found that complete CT (50 mg/L) degradation with GLE (8000 mg/L) for 7d at pH ≥ 10 was achieved. When comparing the effectiveness of between GLE-Powder and GLE-Filtrate, there was nearly no difference (<10% variation). Therefore, subsequent experiments were conducted using GLE-Filtrate at pH 10. The rate of CT degradation with GLE was enhanced in the presence of Fe(II), iron minerals and soils. The results of reaction kinetics between CT and GLE well fitted to the pseudo first-order reaction kinetic model with a rate constant (k1) of 0.284 d-1 and the presence of Fe(II), iron minerals and soils resulted in k1 ranging from 0.386 to 55.44 d-1. Additionally, the specific reaction rate constant (kSA) based on surface area of the iron mineral particles ranged from 1.90 × 10-4 to 4.81 × 10-3 L d-1 m-2. The mechanism of CT degradation mainly followed reductive dechlorination pathway. The results of CT degradation and byproducts formation and the mass balance conducted based on chloride ion exhibited that CT was transformed to chloroform, dichloromethane and chloromethane. Also, activation energy for reaction between GEL-Filtrate and CT was determined to be 66.3 kJ/mole; the presence of Fe2O3 reduced activation energy to 49.8 kJ/mole. These experimental results revealed that CT degradation with GLE exhibited the potential for remediation of chlorinated solvents in soil and groundwater system.
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Cheng, Yu-Ting, and 鄭宇廷. "Anti-angiogenic Potential of Guava Budding Leaf Aqueous Extract in Prostate Cancer Cells." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/45830416817489970452.
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碩士<br>弘光科技大學<br>生物科技研究所<br>97<br>Angiogenesis, the generation of new capillaries through a process of pre-existing microvessel sprouting, is under stringent control and normally occurs only during embryonic and post-embryonic development, reproductive cycle, and wound repair. Usually, an imbalance of the growth factors is involved in this process, resulting in the acceleration of several diseases including malignant, ocular, and inflammatory diseases. Moreover, angiogenesis has been considered to be involved ass an important step in cancer progression. The discovery of key molecular modulators of angiogenesis, notably Vascular Endothelial Growth Factor (VEGF), Basic Fibroblast Growth Factor (bFGF), Matrix Metalloproteinases (MMPs), Interleukin-6 (IL-6) and Interleukin-8 (IL-8) has in reality catalyzed the development of numerous neutralizing therapeutic agents. In this thesis, the effects of the aqueous extract of Psidium guajava L. budding leaves (PE) on antiangiogensis in prostate cancer DU145 cells were investigated using in vivo as well as in vitro models. At a concentration of 1 mg/mL, PE inhibited 69.1% and 76.0% of cell migration capability and expression of vascular endothelial growth factor (VEGF), respectively. At 1 mg/mL, complete inhibition on the expression of MMPs, upregulation of TIMP-2 and inhibition on MMPs were also simultaneously demonstrated. Alternatively, IL-6 and IL-8 were also examined by the Gelatin Zymography and the Elisa Kit Assay. PE inhibited migration and tube formation of Human umbilical vascular endothelial cells (HUVEC) in a concentration dependent manner. More importantly, PE at 25 mg/mL prominently inhibited angiogenesis when demonstrated by Chicken Chorioallantoic Membrane Assay (CAM assay).
To summarize, PE possesses a strong antiangiogenic activity, which on combining its antimigration and anti-invasive potentials may contribute to its cancer chemopreventive capability.
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KU, HUI-HSUAN, and 古慧萱. "Hypoglycemia Effect of Containing Guava Leaf Extract Drink in STZ Induced Diabetic Rats." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/fw9ezw.
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碩士<br>實踐大學<br>食品營養與保健生技學系碩士班<br>106<br>The International Diabetes Federation pointed out that in recent years, the number of people suffering from diabetes worldwide has increased year by year due to aging or long-term abnormal diet such as high-sugar and high-fat diet. Guava leaf extract (GLE) has been indicated the ability of anti-hyperglycemic and anti-hyperlipidemic, probably due to its phenolic content. The purpose of this study is to investigate the effect of hypoglycemia activities of drink containing GLE on high fat high fructose diet rats which is intraperitoneally injected by Streptozotocin (STZ) and Nicotinamide (NA) to induce diabetes. This study use 60 male Sprague-Dawley rats and divide them into 2 groups, one is Normal control group and the other is diabetes-induced group. After the success of inducing diabetes by STZ and NA, the diabetes-induced group are divided into 5 groups, diabetes mellitus group (DM), positive control group (PC), low-dose GLE group (L), medium-dose GLE group (M), and high-dose GLE group (H) respectively. These 5 groups are given GLE for 5 weeks then sacrificed. In the experiment, we test the body weight, diet intake, water intake, fasting blood glucose (FBG), and fasting blood insulin of rats, and do oral sucrose tolerance test (OSucTT) on rats. After sacrificing, we also test blood biochemical value, antioxidant enzyme activity , inflammation, and gene expression in intestine tissue. Results showed that supplement GLE were significant decrease FBG, OSucTT, the area under the blood glucose curve in OSucTT, inflammation, expreesion of Sodium-Dependent Glucose Cotransporters-1（SGLT 1）, Glucose Transporter-2（GLUT 2）and increase antioxidant enzyme activity, TBARS compare with DM group. In conclusion, GLE in this study could improve blood glucose, inflammation, oxidative stress,α-glucosidase inhibitor on hyperglycemic diabetes rats.
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Yu, Shiou-Cherng, and 余修誠. "Phytochemical Characterics and its Effect on Protein Tyrosine Phosphatase 1B of Guava Leaf Extract." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/93g5c9.
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碩士<br>亞洲大學<br>保健營養生技學系<br>105<br>The hypoglycemic potency of guava leaf extract has been reported repeatedly by many research groups. This research was carried out with a focus on purifying the hypoglycemic compounds that reside in the aqueous partition of guava leaf extract, since our laboratory has identified the aqueous partition possesses the most potent hypoglycemic properties in in vivo. The chemical properties, phenol/flavonoid contents and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging ability, of those partitions were similar to other reports. The aqueous partition has the lowest contents in phenolic and DPPH scavenging contents, while its flavonoid content is among the lower groups along with butanol and hot water extracts.
The hypoglycemic compounds in the aqueous partition were further purified by LH -20 (hydroxypropyl dextran) columns with PTP1B inhibition as the screening method. The most potent PTP1B inhibitory fraction comes out after the main peak that suggests the hypoglycemic compound is a small molecule.
The HPLC can further purified the compound to near homogeneity but the acetonitrile inactivate the active compounds. The LC/MS method identified one major species in each of the electron spray, a 428 Da in the negative spray and a 516 Da in the positive spray.
A time course study reveals the aqueous partition has a unique slow inactivation property on PTP 1B enzyme activity. This slow inactivation is much less significant with hot water extract and not observed in other organic partitions. Therefore, it is suggested the inactivation of PTP 1B enzymatic activity is probably through a covalent bond inactivation, such as oxidation of cysteine reside.
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Chang, Yu-Shan, and 張毓珊. "The Bioactive Constituents of Aqueous Guava Budding Leaf Extract and Their Apoptotic Mechanism on DU145 Prostate Cancer Cells." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/76013517176457390412.
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Juan, Hung-Ju, and 阮泓儒. "Effect of Drying Temperature, Duration and Genotype on Antioxidant Capacity and alpha-Amylase Inhibitory Activities of Guava Leaf Extract." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/zp6rgc.
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碩士<br>國立屏東科技大學<br>農園生產系所<br>106<br>Guava is one of the important economic fruit trees in Taiwan. In addition to its fruits, its leaves are rich in antioxidant components and have the potential for the prevention of degenerative diseases. The aim of the present study was to understand the effects of drying temperature and duration on the total phenolic content and antioxidant capacity of guava leaves at young and mature stages. The variations of total phenolic content, antioxidant capacity and α-amylase inhibitory rate among genotypes were also investigated. In total, 36 genotypes were evaluated including six cultivars, five introduced or collected cultivars (line), 23 breeding lines and two related species. The results showed that drying young leaves at 40°C for 48 hours generally had the highest total phenolic content and antioxidant capacity among treatments. However, no significant difference was found between treatments at 40°C and at 50°C for 12 hours. When drying leaves at 50°C for 12 hours, it was found that there were significant variations in total phenolic content, FRAP, DPPH radical-scavenging power and α-amylase inhibitory activity among genotypes. Young leaves were better than mature leaves in terms of total phenolic content and antioxidant capacity. The total phenolic content, FRAP, DPPH scavenging power and α-amylase inhibition rate of the young leaves of the genotypes ranged from 197.89 to 94.52 mg GAE/g, 34.42 to 9.78 g Vitamin C/g, 45.62 to 13.52 g Trolox/g and 79.0% to 13.7%, respectively. Regardless of the leaf ages, total phenolic content is highly significantly correlated with both FRAP and DPPH scavenging power. Genotypes show better quality than the commonly grown cultivars in total phenolic content, antioxidant capacity and α-amylase inhibition rate have been selected. They can be used for further breeding or healthy product development.
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Huang, Lian-Guang, and 黃連光. "Immunomodulatory and adjuvant activities of polysaccharide extract from the leaf of Morinda citrifolia L. (Noni) and Psidium guajava L. (Guava)." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/72181125416385790049.
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碩士<br>國立高雄大學<br>生物科技研究所<br>99<br>In recent years, plant polysaccharides are considered to be an effective and low toxicity of biological response modifiers. Currently, A variety of plant polysaccharides have been used in the development of adjuvant. In this study, the extractions of plant polysaccharides were extracted with water, boiling, hot ethanol from the leaves of guava and noni. By the phenol sulfuric acid method for quantification of total sugar, and then evaluated for its toxicity with MTT assay. Finally, using different polysaccharide extracts with OVA as antigen assess immunemodulatory and adjuvant potential on the specific cellular and humoral immune response. In vitro, noni and guava polysaccharide of leaf extract to 1 mg/ml ~ 2.5 mg/ml doses stimulate macrophage J774A.1 with 80% cell viability. Compared to commercially available plant-derived adjuvant Quil A showed the characteristics of low toxicity. To polysaccharide extract stimulated macrophages and then detection of cytokine expression with real-time PCR such as IFN-r, IL-4, IL-6, IL-12, and analysis of induced immune path. The results showed that guava water extraction (GWps), boiling extraction (GBps), ethanol extraction polysaccharides (GEps) and noni boiled extracts polysaccharide (NBps) can stimulate the expression of Th1 and Th2 cytokines. Noni water extraction (NWps) and ethanol extraction polysaccharides (NEps) can only induce Th1 cytokine expression. Based on total sugar yield, cell toxicity and the effect of cytokine stimulation selection NWps, NBps, GBps and GEps for immune, Quil A as a positive control, PBS as a negative control. In vivo, the Con A and OVA-induced splenocyte proliferation and the serum OVA-specific IgG1 and IgG2a antibody titers in the immunized mice were significantly enhanced. The leaves polysaccharide with Noni and guava also significantly promoted the production of Th1 (IL-12 and IFN-r) and Th2 (IL-4 and IL-6) cytokines and NF-kB transcription factors in splenocytes from the immunized mice. The results indicated that polysaccharide of leaves extract with noni and guava had strong potential to increase both cellular and humoral immune responses, and that is a safe and efficacious adjuvant candidate suitable for a wide spectrum of prophylactic and therapeutic vaccines.
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Pan, Yun-Chieh, and 潘筠捷. "Effect of guava leaf extracts on alcohol-injured rat liver cells." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/23279259133767479211.
Full textAbstract:
碩士<br>國立屏東科技大學<br>食品科學系所<br>98<br>Guava (Psidium guajava L.) is a tropical fruit, which belongs to the family Myrtaceae, widely consumed fresh and also processed (beverages, syrup, jams, and ice cream), it is one of the most important economic fruit in Taiwan. Leaves and fruits of guava have been reported to have anti-diarrheal, hypoglycemic, lipid lowering, antibacterial, antioxidant activities. The sample of this study was guava leaf used different solvents extraction, the cytotoxicity of clone 9 liver cells and the hepatoprotective properties of liver injuries induced by alcohol was investigated. When the clone 9 liver cells were treated with guava leaf extracts for 24 hours, the dose-dependent was found. The aqueous extracts was without cytotoxicity in 400 μg/mL, 200 μg/mL, 100 μg/mL and 50 μg/mL, the 60℃ aqueous extracts was without cytotoxicity in 100 μg/mL and 50 μg/mL. According to ALT (alanine aminotransferase) activities, the acetone extracts in 200 μg/mL, ethanol extracts in 500 μg/mL, 400 μg/mL, 200 μg/mL, 100 μg/mL and 50 μg/mL were normal, the aqueous extracts and 60℃ aqueous extracts were without influence.
The clone 9 liver cells cultivated with 5％ alcohol for 30 minutes has been the alcohol injury cell model in this study. According to wst-1 assay and ALT activities, the hepatoprotective properties of acetone extracts, ethanol extracts and aqueous extracts were significant in 100 μg/mL, 50 μg/mL and 50 μg/mL, respectively, 60℃ aqueous extracts had hepatoprotective properties in 200 μg/mL.
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Wu, Ning-Jung, and 吳寧容. "Hypoglycemic effect of guava (Psidium guajava Linn.) leaf extracts in streptozotocin-nicotinamide induced type 2 diabetic rats." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/48242811810693100226.
Full textAbstract:
碩士<br>國立臺灣大學<br>食品科技研究所<br>95<br>Diabetes mellitus (DM) is one of the major diseases that human being eagerly wants to overcome. In 2006, DM was the fourth of top ten causes of death in Taiwan and more than 95% are type 2 DM. Guava (Psidium guajava Linn.) is one of the most important economic fruit in Taiwan. Leaves and fruit of guava are believed to have hypoglycemic effects which have been popularly employed in traditional DM treatment in Taiwan. However, there is insufficient scientific evidence for guava to cure DM, especially type 2 DM. In the present study, we injected low-dose streptozotocin (STZ) plus nicotinamide (NA) into Sprague-Dawley (SD) rats to induce Type 2 diabetes and to evaluate the antihyperglycemic effect and the carbohydrate metabolism of water and ethanol extracts from guava leaves. The study contains two parts, the acute and the long term experiments. In the acute experiment, the water or ethanol extracts of guava leaves were prepared and in the oral glucose tolerance test (OGTT) was performed to evaluate the hypoglycemic effects. In the long term experiment, we investigated the effect of aqueous or ethanol extracts from guava leaves in STZ–NA induced diabetic rats daily administered for 6 weeks.
Results of the acute experiment showed that plasma glucose levels of the diabetic rats administered with 200 or 400 mg/kg BW of aqueous or ethanol guava leaf extracts were lower than the diabetic control group (p<0.05). This indicated that aqueous or ethanol extracts from guava leaves could effectively delay the rise of plasma glucose after feeding in diabetic rats. Diabetic rats administered with 400 mg/kg BW of aqueous or ethanol guava leaf extracts significantly reduced plasma glucose than 200 mg/kg BW. Therefore, aqueous or ethanol extracts from guava leaves with dosage of 400 mg/kg BW were used to carry out the long term experiments.
The result of the long term experiments, showed that the diabetes groups fed with 400 mg/kg BW of aqueous or ethanol guava leaf extracts presented a significantly reduction of blood sugar level comparing to diabetes and normal groups (both fed with saline) and could delay the elevation of plasma glucose during the OGTT test after the fourth and sixth weeks. The rats were sacrificed at the 6 weeks and the carbohydrate metabolism enzyme activities in liver were measured. The activities of hexokinase, phosphofructokinase, and glucose-6-phosphate dehydrogenas in diabetic rats fed with aqueous guava leaf extracts were higher than those of diabetic control rats (p<0.05), while the activity of fructose-1, 6-bisphosphatase and glucose-6-phosphatase was markedly lower than diabetic control rats (p<0.05). In addition, the activities of hexokinase and glucose-6-phosphate dehydrogenase in diabetic rats fed with ethanol guava leaf extracts were higher than diabetic control rats, while the activities of phosphofructokinase, fructose-1, 6-bisphosphatase, and glucose-6-phosphatase were no different with each group. The blood glucose reduction ability of extracts from guava leaves in diabetic rats may be related with the activity of hepatic carbohydrate metabolic enzymes. In additional, the abilities of glucose uptake and glycogen synthesis are significantly promoted in hepatocytes of diabetic rats treated with aqueous or ethanol extracts from guava leaves. These results indicate that extracts of guava leaves may regulate the plasma glucose in STZ–NA induced type 2 diabetic rats.
Book chapters on the topic "Guava Leaf Extract"
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Otokunefor, Kome, Ifeoma Jacinta Okutalukwe, Edmond Osi Uguomore, and Oghenerukevwe Apuke. "Antibacterial Activity of Ethanol Extracts of Psidium guajava (Guava) and Ocimum gratissmum (Scent Leaf) on Wound Isolates." In Triple Helix Nigeria SciBiz Annual Conference 2024. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-81619-2_22.
Full textConference papers on the topic "Guava Leaf Extract"
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Waresindo, William Xaveriano, Halida Rahmi Luthfianti, Dian Ahmad Hapidin, et al. "The effect of freeze-thaw cycle on the physical properties of PVA/Guava leaf extract hydrogel." In THE 4TH MATERIALS RESEARCH SOCIETY OF INDONESIA (MRS-ID) MEETING. AIP Publishing, 2025. https://doi.org/10.1063/5.0242514.
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Utomo, Wahyu Budi, Barlian Hasan, Fajriyati Mas’ud, Dheby Rhivana, and Syalwa Shada Masyura. "The use of guava (Psidium Guajava) leaf extract as a corrosion inhibitor for iron in acid media." In THE 1ST INTERNATIONAL MULTIDISCIPLINARY CONFERENCE OF APPLIED SCIENCES: Applied Sciences for Sustainable Earth, Environment and Management. AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0221147.
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