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Journal articles on the topic 'Gum and Mucilage's'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Vaishali, S. Kadam G. R. Shendarkar. "ROLE OF NATURAL POLYMER IN SUSTAINED AND CONTROLLED RELEASE." INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH 07, no. 01 (2017): 7390–400. https://doi.org/10.5281/zenodo.1006885.

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Now a day there has been an important development in different dosage forms for existing and newly designed drugs and natural products, and synthetic as well as semi-synthetic excipients always need to be used for a variety of purposes. Gums and mucilages are widely used as natural materials for conventional and novel dosage forms. With the increasing interest in polymers of natural origin, the pharmaceutical world has compliance to use most of them in their formulations. Moreover, the tremendous orientation of Pharmaceutical world towards these naturally derived polymers has become a subject

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2

Haile, Tsadkan Gebremeskel, Gereziher Gebremedhin Sibhat, and Fantahun Molla. "Physicochemical Characterization of Grewia ferruginea Hochst. ex A. Rich Mucilage for Potential Use as a Pharmaceutical Excipient." BioMed Research International 2020 (June 8, 2020): 1–10. http://dx.doi.org/10.1155/2020/4094350.

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Gum and mucilages from natural sources are in recent times increasingly investigated for pharmaceutical applications. Different studies have shown that the gum and mucilage fraction of various species of the genus Grewia were found to be effective viscosity enhancers, stabilizers, disintegrants, suspending agents, gelling agents, bioadhesives, film coating agents, and binders. However, no study has been conducted on the potential use of Grewia ferruginea mucilage (GFM) as a pharmaceutical excipient. Therefore, this study was aimed at characterizing the Grewia ferruginea bark mucilage for its p

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3

Santos, Francislaine Suelia dos, Rossana Maria Feitosa de Figueirêdo, Alexandre José de Melo Queiroz, et al. "Influence of Dehydration Temperature on Obtaining Chia and Okra Powder Mucilage." Foods 12, no. 3 (2023): 569. http://dx.doi.org/10.3390/foods12030569.

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Gum and mucilage from seeds and fruits are objects of study because they have characteristics of high viscosity at low concentrations and gelling properties, which are useful characteristics for modifying the texture and stabilizing products in the food industry. Chia and okra have high concentrations of polysaccharide gums in their composition, which makes them an interesting target for use in the composition of foods that require the use of texture enhancers and stabilizers. The present study investigated the influence of dehydration temperature on the characteristics of chia and okra powder

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4

Singh, Sudarshan, and Hitesha Goswami. "Formulation of Oral Mucoadhesive Tablets of Pioglitazone using Natural Gum from Seeds of Pithecellobium Dulce." International Journal of Pharmaceutical Sciences and Nanotechnology 8, no. 4 (2015): 3031–38. http://dx.doi.org/10.37285/ijpsn.2015.8.4.6.

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 The plant derived gums and mucilage’s comply with many requirements of pharmaceutical excipients as they are non-toxic, stable, easily available, associated with less regulatory issues as compared to their synthetic counterpart and inexpensive; also these can be easily modified to meet the specific need. The present study was undertaken to isolate mucilage from the seeds of Pithecellobium dulce (P. dulce). The mucilage isolated from P. dulce were used as a bioadhesive polymer in tablet formulation and evaluated for the parameters such as swelling, pH, and bioadhesive property like bioad

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5

Mohd., Shahid Khan, Arora Pankaj, Kalra Naresh, Arora Namita, Purva Arushi, and Sharma Neha. "Qualitative Phytochemical Analysis of Ethanolic Extracts of Hibiscus laevis Flowers and Euryale ferox Seeds." International Journal of Current Pharmaceutical Review and Research 14, no. 04 (2022): 69–75. https://doi.org/10.5281/zenodo.12657567.

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The purpose of the research was to determine whether or not H. laevis and E. ferox had anypotential in the field of phytochemistry. Ethanol was the solvent of choice for the extractionprocess of both the flowers of H. laevis and the seeds of E. ferox. There is evidence of thepresence of alkaloids, glycosides, carbohydrates, phytosterols, gum, and mucilage in theethanolic extract of H. laevis. On the other hand, there was a lack of steroidal compounds,protein and amino acids, tannins, saponins, oil, and lipids. The ethanolic extract of E. ferox,on the other hand, reveals the presence of alkaloi

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6

SILVEIRA, M. C. A., R. S. L. GLÓRIA, K. M. BARBOSA, and L. S. S. SANTOS. "POTENTIAL USE OF MANGO GUM (MANGIFERA INDICA) IN PHARMACOLOGICAL SYSTEMS." Periódico Tchê Química 16, no. 33 (2019): 688–706. http://dx.doi.org/10.52571/ptq.v16.n33.2019.703_periodico33_pgs_688_706.pdf.

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The possibility of using natural or modified polymers to formulate drug-containing nanocapsules is a pharmaceutical option for cases in which an increase in the half-life of medications in the body and a decrease in side effects is required, and may also be used for better pharmacological targeting of the site. Related to low production costs with these characteristics and renewable availability. Gums and mucilages have been studied for use in natural alternative drug delivery systems. The gum from the trunk of Mangifera indica has few studies aimed at this purpose, although it has shown promi

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7

Mohd., Shahid Khan, Arora Pankaj, Kalra Naresh, Arora Namita, Purva Arushi, and Sharma Neha. "Qualitative Phytochemical Analysis of Ethanolic Extracts of Hibiscus laevis Flowers and Euryale ferox Seeds." International Journal of Current Pharmaceutical Review and Research 14, no. 4 (2022): 69–75. https://doi.org/10.5281/zenodo.7612822.

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The purpose of the research was to determine whether or not <em>H. laevis</em> and <em>E. ferox</em> had any potential in the field of phytochemistry. Ethanol was the solvent of choice for the extraction process of both the flowers of <em>H. laevis</em> and the seeds of E. ferox. There is evidence of the presence of alkaloids, glycosides, carbohydrates, phytosterols, gum, and mucilage in the ethanolic extract of <em>H. laevis</em>. On the other hand, there was a lack of steroidal compounds, protein and amino acids, tannins, saponins, oil, and lipids. The ethanolic extract of E. ferox, on the o

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8

Saraf, Sampada. "Investigating the Anti-Allergic, Bronchoprotective, and Antioxidant Activities of Psidium guajava Extract in Experimental Animals: A Comprehensive Study." Journal of Internal Medicine and Pharmacology (JIMP) 1, no. 02 (2024): 33–43. https://doi.org/10.61920/jimp.v1i02.25.

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The utilization of gum and mucilages in modern pharmaceutical practices has emerged as a pivotal area of research, offering multifaceted contributions to drug development and formulation. This abstract delves into the significance of these natural polymers, exploring their diverse roles and applications. Gums, derived from plant exudates, and mucilages, extracted from plant seeds and tissues, serve as versatile excipients, providing unique properties such as viscosity, stability, and bioadhesion. In pharmaceutical formulations, these substances act as binders, disintegrants, and sustained-rele

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9

Alhssan, Eiman, Songül Şahin Ercan, and Hüseyin Bozkurt. "Effect of Flaxseed Mucilage and Gum Arabic on Probiotic Survival and Quality of Kefir during Cold Storage." Foods 12, no. 3 (2023): 662. http://dx.doi.org/10.3390/foods12030662.

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This study aimed to assess the survival of probiotic cultures in kefir. Kefir is a fermented dairy product, and in this study we incorporated nutritionally rich flaxseed mucilage and gum arabic as a prebiotic, then monitored for improvement in the the viability of Lactobacillus acidophilus and Bifidobacterium lactis. In addition, some physicochemical variables of kefir were investigated. The addition of flaxseed mucilage and gum arabic significantly (p ˂ 0.05) increased the growth of both Lactobacillus acidophilus and Bifidobacterium lactis compared to the control. Samples enriched with flaxse

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Quezada Moreno, Walter, Edwin Cevallos Carvajal, Marcia Yomara Proaño, et al. "Thickening capacity of Cordia lutea Lam mucilage gum in a liquid soap formulation." Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry 80, no. 599 (2023): 133–41. http://dx.doi.org/10.55815/418005.

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The study refers to the use of Cordia lutea Lam gum as a natural thickener in a liquid soap formulation. The aim was to determine the phytochemical components and the thickening capacity of mucilage gum in a liquid soap formula. The color of the fruit and the mucilage gum were determined by CIELab methodology, the phytochemical screening of the mucilage gum extracted by manual pressure, by rapid chemical reactions. The hydrocarbons were determined by gas chromatography and the viscosity using a rotational viscometer. Liquid soap was made according to a commercial formula using a DCA design alo

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11

Mohd Zain, Norashikin, Maaruf Abd. Ghani, Zalifah Mohd Kasim, and Haslaniza Hashim. "Effects of Different Drying Methods on the Functional Properties and Physicochemical Characteristics of Chia Mucilage Powder (Salvia hispanica L.)." Sains Malaysiana 50, no. 12 (2021): 3603–15. http://dx.doi.org/10.17576/jsm-2021-5012-12.

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Chia seeds are a healthy source of omega-3 fatty acids and dietary fibre. The effects of different drying methods (freeze-drying and oven-drying) on the functional properties (water holding capacity, oil holding capacity and colour analysis) and physicochemical characteristics (scanning electron microscopy) of chia mucilage powder (Salvia hispanica L.) including comparison with xanthan gum, hydroxypropyl methylcellulose (HPMC), and arabic gum were investigated. Chia mucilage dried in a freeze dryer (FD) showed significantly higher (p<0.05) values of water holding and oil holding capacities

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Haile, Tsadkan Gebremeskel, Gereziher Gebremedhin Sibhat, Ebisa Tadese, Desta Tesfay, and Fantahun Molla. "Evaluation of Grewia ferruginea Hochst ex A. Rich Mucilage as Suspending Agent in Metronidazole Benzoate Suspension." BioMed Research International 2020 (October 29, 2020): 1–12. http://dx.doi.org/10.1155/2020/7612126.

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Various species of the genus Grewia have been investigated for different pharmaceutical applications as excipients, yet a study on the potential use of Grewia ferruginea mucilage (GFM) as a suspending agent is lacking. Thus, this study is aimed at evaluating the efficacy of Grewia ferruginea mucilage (GFM) as a suspending agent in metronidazole benzoate suspension. The suspensions were prepared using 0.5%, 1%, 1.5%, and 2% w / v of GFM and compared with suspensions prepared from xanthan gum (XGM) and sodium carboxyl methyl cellulose (SCMC) in similar concentrations. The prepared suspensions we

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13

Bansal, Keshav, and Meenakshi Bajpai. "Design of Solid Dosage Form using Isolated Mucilage from Cassia fistula." Research Journal of Biotechnology 16, no. 11 (2021): 51–68. http://dx.doi.org/10.25303/1611rjbt5168.

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The present study was aimed to isolate and characterize mucilage obtained from the leaves of Amaltas (Cassia fistula) and to check the binding efficiency by comparing with gum acacia. Isolation of mucilage was done by hot maceration process and investigated for various physicochemical characterization and in vitro dissolution profile to check mucilage as a binding agent. Different batches (KF1 – KF4) of paracetamol tablets of different concentration of mucilage (3%, 5%, 10% and 15% w/v) were prepared by wet granulation method. All the parameters of uncoated tablets were performed and compared

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14

Singh, Sudarshan, and Sunil B. Bothara. "Physico-chemical and structural characterization of mucilage isolated from seeds of Diospyros melonoxylon Roxb." Brazilian Journal of Pharmaceutical Sciences 50, no. 4 (2014): 713–25. http://dx.doi.org/10.1590/s1984-82502014000400006.

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Mucilage was isolated from the seeds of Diospyros melonoxylonRoxb., a plant growing naturally in the forests of India. Various physico-chemical methods like particle analysis, scanning electron microscopy, differential scanning calorimetry, differential thermal analysis, thermogravimetry analysis, molecular weight by gel permeation chromatography, rheometry, elemental analysis, x-ray diffraction spectrometry, zeta potential, fourier transform infrared spectroscopy, 1D(1H and 13C) (NMR) have been employed to characterize this gum in the present study. Particle analyses suggest that mucilage had

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15

Nabila Nabila and Sry Ulina Karo-Karo. "Exploring natural disintegrant as alternative excipients sources for tablet formulation: A systematic review." International Journal of Science and Research Archive 13, no. 2 (2024): 3296–305. https://doi.org/10.30574/ijsra.2024.13.2.2530.

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Optimizing the disintegration and dissolution of orally administered tablets is crucial for releasing active pharmaceutical ingredients (APIs) for absorption. This review explores disintegrant research, focusing on natural super disintegrants and co-processed excipients that collected from 2010-2024. Natural disintegrants such as Silicified Oryza Sativa Starch, Plantago ovata mucilage, and gum karaya show promising results. Silicified Oryza Sativa Starch enhances paracetamol tablet disintegration, while Plantago ovata mucilage outperforms Crosspovidone. Gum karaya offers a cost-effective, bioc

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16

A.Abdulrasool, Alaa, Abdulmuttalib A.Naseer, and Firas A.Rahi. "Application of Seed Mucilage Extracted from Lallemantia royleana as a Suspending Agent." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 20, no. 1 (2017): 8–13. http://dx.doi.org/10.31351/vol20iss1pp8-13.

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The mucilage from the seeds of Lallemantia royleana family Labiatae was extracted and subjected to preformulation study for evaluation of its suitability for use as suspending agent. Furosemide suspensions were prepared using (1.5% w/v) of the extracted Lallemantia royleana mucilage, (1.5% w/v) chitosan and (0.35% w/v) xanthan gum. The mucilage was white in color and the average yield of dried mucilage obtained from L.royleana nutlets was 14 % w/w of the seeds used. It is sparingly soluble in water but swells in contact with it, giving a highly viscous solution. It is slightly acidic to neutra

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17

Singh, Sudarshan, and Sunil B. Bothara. "Manilkara zapota (Linn.) Seeds: A Potential Source of Natural Gum." ISRN Pharmaceutics 2014 (March 4, 2014): 1–10. http://dx.doi.org/10.1155/2014/647174.

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Mucilage isolated from seeds of Manilkara zapota (Linn.) P. Royen syn. is a plant growing naturally in the forests of India. This mucilage is yet to be commercially exploited, and characterized as polymer. Various physicochemical methods like particle size analysis, scanning electron microscopy, thermal analysis, gel permeation chromatography, X-ray diffraction spectrometry, zeta potential, Fourier transform infrared spectroscopy, and nuclear magnetic resonance spectroscopy have been employed to characterize this gum in the present study. Particle size analyses suggest that mucilage has partic

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18

Priya, Patil*and Vijay R. Mahajan. "FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLET QUETIAPINE FUMARATE BY USING NATURAL POLYMER." Indo American Journal of Pharmaceutical Sciences 04, no. 12 (2018): 4859–67. https://doi.org/10.5281/zenodo.1134591.

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The purpose of present study was to develop once a day sustained release matrix tablet of Quetiapine Fumarate by using natural polymer viz. Xanthan gum and isolated fenugreek mucilage. Varying ratios of drug and polymer like were selected for sustained release tablet by using direct compression method. After fixing the ratio of drug and polymer for Sustain the release of drug up to desired time, the release rates were modulated by combination of two different rates controlling material and triple mixture of two different rate controlling material. After evaluation of physical properties of tab

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19

Vera, Natalia, Laura Laguna, Liliana Zura, and Loreto A. Muñoz. "A Comparative Study of the Physical Changes of Two Soluble Fibers during In Vitro Digestion." Proceedings 53, no. 1 (2020): 21. http://dx.doi.org/10.3390/proceedings2020053021.

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This research aimed to compare the apparent viscosity and the degree of fragmentation/aggregation produced in dispersions of xanthan gum and chia mucilage during the gastrointestinal tract by using an in vitro digestion. Both soluble fibers exhibited pseudoplastic behavior, independent of the concentration and stage of digestion (oral, gastric or intestinal). The viscosity decreased from the oral to intestinal stage in all the concentrations, produced mainly by the “dilution effect” by the addition of digestive fluids. The particle size of xanthan gum increased drastically in the gastric stage

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20

Samanta, Radheshyam, Asish Bhaumik, and Amit Kumar Nayak. "The Assessment of Mucoadhesivity of Natural Polymer Derived Form Plant Sources." Journal of Drug Delivery and Therapeutics 10, no. 2-s (2020): 27–29. http://dx.doi.org/10.22270/jddt.v10i2-s.3952.

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The main aim and objective of my present research work was to determine the various important mucoadhesive parameters such as mucoadhesive force, force of adhesion and bonding strength etc. Mucoadhesive properties of natural polymers were evaluated by formulating gels using Carbopol 940 P as a gelling agent. Mucoadhesive parameters of the prepared Carbopol 940 P gels containing natural polymers were determined by ex vivo followed by modified physical balance using excised cock intestinal mucosa. From the recent experimental data it was displayed that the mucoadhesive strength, force of adhesio

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Soleimani-Rambod, Afshin, Shahin Zomorodi, Shahram Naghizadeh Raeisi, Asghar Khosrowshahi Asl, and Seyed-Ahmad Shahidi. "The Effect of Xanthan Gum and Flaxseed Mucilage as Edible Coatings in Cheddar Cheese during Ripening." Coatings 8, no. 2 (2018): 80. http://dx.doi.org/10.3390/coatings8020080.

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The object of this study was to investigate the possibility of using xanthan gum and flaxseed mucilage as edible coatings for Cheddar cheese during ripening for 90 days. Five samples of Cheddar cheese blocks were coated with different coating materials in triplicate as follows: Coated with polyvinyl acetate as control (C), coated with 0.5% xanthan gum (XG), coated with 0.75% flaxseed mucilage (FM1), coated with 1% flaxseed mucilage (FM2), and coated with 1.25% flaxseed mucilage (FM3). All samples were kept at 8 ± 2 °C in a cold room for 90 days. The statistical analysis of the results showed t

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Masugossa, Mariana Justino, Viviane da Silva Mendoza, Nailene de Freitas Ortega, Silvia Sayuri Yahagi, Clitor Junior Fernandes de Souza, and Eliana Janet Sanjinez Argandoña. "Use of Ora-pro-nóbis (Pereskia aculeata Miller) mucilage as a wall material in microencapsulation by complex coacervation." Acta Scientiarum. Technology 46, no. 1 (2023): e64375. http://dx.doi.org/10.4025/actascitechnol.v46i1.64375.

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Innovative materials for the encapsulation of bioactive compounds are a permanent challenge. In this sense, the purpose of the study was to evaluate the use of Ora-pro-nobis mucilage (MOPN) as a wall material to replace Arabic gum (AG), in microencapsulation by complex coacervation of bocaiuva (Acrocomia aculeata) pulp oil. The MOPN was obtained from green leaves, and the pH, color, water activity, humidity, fixed mineral residue, proteins, lipids, and extraction effectiveness were determined. MOPN was employed as a partial or total replacement of AG in the microencapsulation of bocaiuva pulp

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Sudarshan, Singh, and Bothara Sunil B. "In vivo mucoadhesive strength appraisal of gum Manilkara zapota." Brazilian Journal of Pharmaceutical Sciences 51, no. 3 (2015): 689–98. http://dx.doi.org/10.1590/s1984-82502015000300021.

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The mucilage (MMZ) extracted from the seeds of Manilkara zapota(Linn.) P. Royen syn. using maceration techniques was evaluated for mucoadhesive strength by various in vitro and in vivo methods. The result showed that mucoadhesive strength of seeds mucilage have comparable property toward natural and synthetic polymers such as Guar Gum and hydroxyl propyl methyl cellulose (HPMC E5LV) under the experimental conditions used in this study. Briefly, it could be concluded that the seed mucilage of Manilkara zapota can be used as a pharmaceutical excipient in oral mucoadhesive drug delivery systems.

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Prajapati, Bhupendra, Rajdip Goswami, Saikat Santra, Bhaskar Pal, and Biswajit Basu. "Improvement of pharmacokinetic properties and release of aceclofenac swellable matrix tablets utilizing okra (Abelmoschus Esculentus) and Hibiscus Leaf (Hibiscus Rosa-Sinensis) natural polymer mucilage." IP International Journal of Comprehensive and Advanced Pharmacology 9, no. 2 (2024): 130–38. http://dx.doi.org/10.18231/j.ijcaap.2024.019.

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To Development and Evaluation of Aceclofenac Swellable Matrix Tablets Utilizing Okra (Abelmoschus Esculentus) and Hibiscus Leaf (Hibiscus Rosa-Sinensis) Natural Polymer Mucilage as Release Modifier. This study investigates the development of sustained-release Aceclofenac tablets using natural polymers, Okra Gum and Hibiscus Leaf Mucilage, to enhance drug efficacy, reduce dosing frequency, and minimize adverse effects in the treatment of inflammation and pain.: Sustained-release NSAID formulations using natural polymers like Okra Gum and Hibiscus Leaf Mucilage enhance drug efficacy, patient adh

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Bégin, F., C. Vachon, J. D. Jones, P. J. Wood, and L. Savoie. "Effect of dietary fibers on glycemia and insulinemia and on gastrointestinal function in rats." Canadian Journal of Physiology and Pharmacology 67, no. 10 (1989): 1265–71. http://dx.doi.org/10.1139/y89-201.

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The effects of purified and semipurified dietary fiber supplements on glycemia and insulinemia were measured simultaneously with their effects on digestive tract function in the rat. An insoluble fiber (cellulose) and four soluble fibers (guar gum, carboxymethylcellulose, mustard mucilage, and oat β-glucan) were added separately to a fiber-free solid diet and fed to Sprague–Dawley rats for 10 days. Guar gum and oat β-glucan reduced the food intake, whereas cellulose increased it. Guar gum reduced weight gain. Cellulose increased the protein efficiency ratio. After a 13-h fast, glycemia and ins

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Gupta, Kajal. "Formulation and Evaluation of Metformin Using Fenugreek Seed Mucilage Used as a Natural Polymer." International Journal of Advanced Pharmaceutical Sciences and Research 4, no. 4 (2024): 35–41. http://dx.doi.org/10.54105/ijapsr.f4051.04040624.

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The major goal of this study was to develop and test metformin sustained release tablets employing fenugreek seed mucilage (FSM) as a new binder, as opposed to standard polymers such as xanthan gum and HPMC. The study shows how FSM provides sustained medication release while keeping metformin physicochemical characteristics. The sustained-release matrix tablets were made on a laboratory scale utilizing the wet granulation process. 5 batches were created, each with varying quantities of fenugreek seed mucilage, xanthan gum, and HPMC. To examine the tablet's physical properties and consistency,

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Kajal, Gupta. "Formulation and Evaluation of Metformin Using Fenugreek Seed MucilageUsed as a Natural Polymer." International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR) 4, no. 4 (2024): 35–41. https://doi.org/10.54105/ijapsr.F4051.04040624.

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<strong>Abstract: </strong>The major goal of this study was to develop and test metformin sustained release tablets employing fenugreek seed mucilage (FSM) as a new binder, as opposed to standard polymers such as xanthan gum and HPMC. The study shows how FSM provides sustained medication release while keeping metformin physicochemical characteristics. The sustained-release matrix tablets were made on a laboratory scale utilizing the wet granulation process. 5 batches were created, each with varying quantities of fenugreek seed mucilage, xanthan gum, and HPMC. To examine the tablet's physical p

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Venegas-García, Deysi J., and Lee D. Wilson. "Utilization of Bioflocculants from Flaxseed Gum and Fenugreek Gum for the Removal of Arsenicals from Water." Materials 15, no. 23 (2022): 8691. http://dx.doi.org/10.3390/ma15238691.

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Mucilage-based flocculants are an alternative to synthetic flocculants and their use in sustainable water treatment relates to their non-toxic and biodegradable nature. Mucilage extracted from flaxseed (FSG) and fenugreek seed (FGG) was evaluated as natural flocculants in a coagulation–flocculation (CF) process for arsenic removal, and were compared against a commercial xanthan gum (XG). Mucilage materials were characterized by spectroscopy (FT-IR, 13C NMR), point-of-zero charge (pHpzc) and thermogravimetric analysis (TGA). Box–Behnken design (BBD) with response surface methodology (RSM) was u

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Daraghmah, Fayez Sati, and Tawfiq Qubbaj. "Impact of gum arabic and cactus mucilage as potential coating substances combined with calcium chloride treatment on tomato (Solanum lycopersicum L.) fruit quality attributes under ambient storage conditions." Canadian Journal of Plant Science 102, no. 2 (2022): 375–84. http://dx.doi.org/10.1139/cjps-2021-0164.

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The current work investigates the impact of postharvest applications of calcium chloride (CaCl2) in combination with either 10% gum arabic or 50% cactus mucilage on the quality parameters and storability of tomato fruit (Izmir variety), at ambient storage conditions [21 ± 1 °C, relative humidity (RH) 45% ± 2%]. The tomato fruits were dipped in 6% CaCl2 for 10 min and then coated with either 10% gum arabic or 50% cactus mucilage for 3 min. During the time-course of storage, the fruit attributes, such as fresh fruit weight loss, fruit decay, firmness, titratable acidity (TA), total soluble solid

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Chaudhari, SR, and UR Dhuppad. "Isolation of Gum from Tamarind and Fenugreek Plants and Its Evaluation as Pharmaceutical Excipients." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 13, no. 04 (2023): 1509–13. http://dx.doi.org/10.25258/ijddt.13.4.59.

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In contemporary pharmaceutical dosage forms, a variety of auxiliary substances are combined with active compounds to aid in production and achieve the intended effects of the active components. Plant gum is a widely recognized polysaccharide within the pharmaceutical industry, performing an array of functions including stabilizing, disintegrating, suspending, emulsifying, and gelling. Naturally occurring gum is preferred over commercially produced gum due to its affordability, emollient properties, non-irritating nature, natural composition, and lack of toxicity. The costly nature, hazardous p

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Souza, Gabriela, Suelen Siqueira dos Santos, Rita Bergamasco, Jessica Antigo, and Grasiele Scaramal Madrona. "Antioxidant activity, extraction and application of psyllium mucilage in chocolate drink." Nutrition & Food Science 50, no. 6 (2020): 1175–85. http://dx.doi.org/10.1108/nfs-07-2019-0211.

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Purpose The purpose of this study is to extract psyllium mucilage and evaluate its antioxidant compounds (in the best extraction condition) and its application in a chocolate drink. Design/methodology/approach First, the extraction by ultrasonic bath was evaluated, followed by water bath extraction, and as there was no difference between the methods, a water bath experimental design was carried out to evaluate the best extraction conditions for psyllium mucilage, having response variables, yield and emulsion stability. A chocolate drink with psyllium mucilage was produced and evaluated in the

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Nep, Elijah I., Patricia O. Odumosu, Ndidi C. Ngwuluka, Patrick O. Olorunfemi, and Nelson A. Ochekpe. "Pharmaceutical Properties and Applications of a Natural Polymer from Grewia mollis." Journal of Polymers 2013 (July 21, 2013): 1–8. http://dx.doi.org/10.1155/2013/938726.

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The use of naturally occurring biocompatible materials has been the focus of recent research activity in the design of dosage forms for immediate and controlled release formulations. Grewia gum is an intracellular gum obtained by extraction from the inner stem bark of the shrub Grewia mollis (Malvaceae). It grows abundantly (wild or cultivated) in the middle belt region of Nigeria, and the mucilage has been used by indigenes of this belt as thickener in soups. Grewia gum has been investigated for potential applications in pharmaceutical dosage forms. The industrial extrapolation of the applica

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Goyal, Rohit, Manju Nagpal, Sandeep Arora, and Gitika Arora Dhingra. "Development and Optimization of Fast Dissolving Tablets of Losartan Potassium Using Natural Gum Mucilage." Journal of Pharmaceutical Technology, Research and Management 1, no. 2 (2013): 153–69. http://dx.doi.org/10.15415/jptrm.2013.12009.

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Sukhavasi, Sudheshnababu, and V. Sai Kishore. "Formulation and evaluation of fast dissolving tablets of amlodipine besylate by using Fenugreek seed mucilage and Ocimum basilicum gum." International Current Pharmaceutical Journal 1, no. 9 (2012): 243–49. http://dx.doi.org/10.3329/icpj.v1i9.11614.

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Fast dissolving/disintegrating tablets have received ever-increasing demand during the last decade, and the field has became a rapidly growing area in the pharmaceutical area. Particularly the fast dissolving drug delivery systems formulated with natural polymers have more demand because natural materials like gums and mucilages have been extensively used in the field of drug delivery for their easy availability, ease administration, non toxicity, non irritant nature etc. The main aim of the present study was to formulate the fast dissolving tablets of amlodipine besylate tablets using Fenugre

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Chatterjee, Shayeri, and Rana Mazumder. "NOVEL APPROACH OF EXTRACTION AND CHARACTERIZATION OF OKRA GUM AS A BINDER FOR TABLET FORMULATION." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (2019): 189. http://dx.doi.org/10.22159/ajpcr.2018.v12i1.29053.

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Objective: The major objective of the present investigation was to extract a natural polymer (okra gum) with its characterization as pharmaceutical binder and to formulate, develop, and evaluate the compression-coated tablet using okra as binder along with synthetic hydrophilic polymers like various grades of hydroxypropyl methylcellulose (HPMC).Methods: A novel extraction method was carried out using fresh unripe pods of okra (ladies finger) with the aid of organic solvents and its characterization was done. The core tablets were prepared by direct compression method which was compression coa

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Chatterjee, Shayeri, and Rana Mazumder. "NOVEL APPROACH OF EXTRACTION AND CHARACTERIZATION OF OKRA GUM AS A BINDER FOR TABLET FORMULATION." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (2019): 189. http://dx.doi.org/10.22159/ajpcr.2019.v12i1.29053.

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Objective: The major objective of the present investigation was to extract a natural polymer (okra gum) with its characterization as pharmaceutical binder and to formulate, develop, and evaluate the compression-coated tablet using okra as binder along with synthetic hydrophilic polymers like various grades of hydroxypropyl methylcellulose (HPMC).Methods: A novel extraction method was carried out using fresh unripe pods of okra (ladies finger) with the aid of organic solvents and its characterization was done. The core tablets were prepared by direct compression method which was compression coa

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ADAMU, Yahaya Yakubu. "Investigation of Grewia mollis Gum as Biopolymer Drag Reducing Agent." ABUAD Journal of Engineering and Applied Sciences 2, no. 1 (2024): 1–9. http://dx.doi.org/10.53982/ajeas.2024.0201.01-j.

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The hydraulic fracturing treatment relies heavy on fracturing fluid. Finding inexpensive polymer that lowers the pressure gradient in turbulent flow systems during hydraulic fracturing is crucial for the development of shale gas. Most researches focused on investigating the effects of polymers such as partially hydrolysed polyacrylamide, polyethylene oxide, guar gum, xanthan gum and synergies of mixtures as friction reducing polymers. The use of Grewia Mollis mucilage as the natural polymer as a potential friction reducer in slickwater fracturing treatment was the main focus of this study. The

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Singh, Sudarshan, and Sunil B. Bothara. "Development of Oral Mucoadhesive Tablets of Losartan Potassium using Natural Gum from Manilkara Zapota Seeds." International Journal of Pharmaceutical Sciences and Nanotechnology 6, no. 4 (2013): 2245–54. http://dx.doi.org/10.37285/ijpsn.2013.6.4.7.

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The present investigation reports the isolation of mucilage from Manilkara zapota seeds as per AOAC guideline and evaluating it as mucoadhesive agent. Manilkara zapota (Linn.) P. Royen syn. a small tree belonging to family sapotaceae. Physiochemical characteristics of mucilage, such as swelling index, microbial count, viscosity, hydration capacity, flow property, and pH were studied. The mucilage was evaluated for its mucoadhesive properties in compressed tablet, using losartan potassium as model drug. Granules were prepared by wet granulation process using polyvinylpirrolidone as binding agen

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Seke, Faith, Vimbainashe E. Manhivi, Retha M. Slabbert, Yasmina Sultanbawa, and Dharini Sivakumar. "In Vitro Release of Anthocyanins from Microencapsulated Natal Plum (Carissa macrocarpa) Phenolic Extract in Alginate/Psyllium Mucilage Beads." Foods 11, no. 17 (2022): 2550. http://dx.doi.org/10.3390/foods11172550.

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Natal plum (Carissa macrocarpa) contains anthocyanins, cyanidin 3-O-β-sambubioside (Cy-3-Sa), and cyanidin 3-O-glucoside (Cy-3-G) that possess great bioactive properties. During in vitro gastrointestinal digestion, Cy-3-Sa and Cy-3-G are highly sensitive to pH changes and have low bioaccessibility rates of 7.9% and 22%, respectively. This study aimed to therefore use microencapsulation techniques to improve the bioaccessibility of Cy-3-Sa and Cy-3-G. The crude anthocyanin-rich extract was extracted from freeze-dried Natal plum fruit using ultrasonic-assisted ethanol extraction. The anthocyanin

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Hashemi Gahruie, Hadi, Reza Safdarianghomsheh, Parisa Zamanifar, Shahriyar Salehi, Mehrdad Niakousari, and Seyed Mohammad Hashem Hosseini. "Characterization of Novel Edible Films and Coatings for Food Preservation Based on Gum Cordia." Journal of Food Quality 2020 (September 1, 2020): 1–7. http://dx.doi.org/10.1155/2020/8883916.

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As a pharmaceutical component, gum Cordia has been applied to improve crop resistance against many diseases. A large amount of gum appears around the fruit after soaking in an aqueous system. The mucilage possesses outstanding technofunctional properties as an emulsifier, thickening agent, and binding and stabilizing component in food and drug industries. The backbone of gum Cordia is composed of (1-2)-linked L-arabinofuranosyl and (1–6)-linked D-glucopyranosyl residues. This manuscript reviews the technofunctional properties and applications of gum Cordia in food systems. Particularly, our fo

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Shende, M. A., and R. P. Marathe. "OPTIMIZATION OF GASTROADHESIVE DELIVERY SYSTEM FOR NARROW ABSORPTION WINDOW DRUG USING NATURAL POLYMERS." INDIAN DRUGS 53, no. 10 (2016): 63–69. http://dx.doi.org/10.53879/id.53.10.10570.

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A system comprising mechanisms of gastric retention by gastroadhesion has been investigated employing combination of hibiscus esculentus mucilage and xanthan gum for diltiazem hydrochloride. Various formulations of diltiazem hydrochloride were prepared by wet granulation technique using Box-Behnken approach and were tested for compatibility, swelling behaviour, in vitro drug release, mucoadhesive strength and accelerated stability. The percent cumulative drug release at 8th hr (Y1), time to release 80 % of drug (Y2), mucoadhesive strength (Y3) and mucoadhesive time (Y4) were used as the formul

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Singh, Sudarshan, Tanvi R. Dodiya, Rajesh Dodiya, Sangeeta Singh, and Sunil B. Bothara. "In vivo, ex vivo and in vitro Mucoadhesive Strength Assessment of Potential Pharmaceutical Bio-resource Polymer from Diospyros melonoxylon Roxb seeds." International Journal of Pharmaceutical Sciences and Nanotechnology 14, no. 1 (2021): 5307–14. http://dx.doi.org/10.37285/ijpsn.2021.14.1.6.

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In this study, an oral bio-based mucoadhesive polymer was developed from Diospyros melonoxylon Roxb (Ebenaceae) seed mucilage and evaluated for mucoadhesive strength. The mucilage showed shear stress results (0.140 ± 0.0007N), with comparable adhesiveness to HPMC E5 (0.098 ± 0.0008N). Force of adhesion required to detach the seed mucilage and HPMC E5 tablets from the mucin of intestinal tissue were 0.0509 ± 0.0007 (N) and 0.0049 ± 0.0006 (N). Seed mucilage revealed significant higher detachment time, erosion time, in vitro wash off time and ex vivo residence compared to HPMC E5 and lactose tab

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Gorakhnath, Mr Ghodke Shubham, and Dr Hingane L. D. "Characterization of Fenugreek Seeds Mucilage and its Evaluation as Suspending Agent." International Journal for Research in Applied Science and Engineering Technology 10, no. 6 (2022): 4382–86. http://dx.doi.org/10.22214/ijraset.2022.44934.

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Abstract: The present study was undertaken to extract mucilage from fenugreek seeds and evaluate it as suspending agent for pharmaceutical dosage forms. ThePercentage yield of Fenugreek seed mucilage was foundto be 18-20 %. Zinc oxide suspension (20% w/v) was prepared using the mucilage of fenugreek seed as a suspending agent, and it was evaluated for its stability parameters like, sedimentation volume, degree of flocculation, and redispersibility. The effect of the mucilage as the suspending agent was compared with commonly used suspending agents such as, tragacanth and acacia at the concentr

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Yukti, Mahajan* Dev Raj Sharma Pravin Kumar Mahender Singh Ashawat. "Natural Polymers as Excipient in Formulation of Novel Drug Delivery System." Int. J. in Pharm. Sci. 1, no. 8 (2023): 50–71. https://doi.org/10.5281/zenodo.8229107.

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The therapeutic formulation has two main components which are active pharmaceutical ingredients and excipients to support into the production process in addition to enhancing medication distribution. In manufacturing dosage forms, to improve physicochemical parameters and to improve the stability of the dosage form excipients have proven to be very helpful. Excipients are currently utilized in novel drug delivery technology to fulfil customized functions, and in some cases, they directly or indirectly influence the extent and rate of drug release and effectiveness. Advances in polymer science

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Singh, Sudarshan, Tanvi R. Dodiya, Sangeeta Singh, Rajesh Dodiya, and Sunil B. Bothara. "Bio-based Polymer Isolated from Seeds of Buchanania lanzan Spreng with Potential Use as Pharmaceutical Mucoadhesive Excipient." International Journal of Pharmaceutical Sciences and Nanotechnology 13, no. 4 (2020): 5028–35. http://dx.doi.org/10.37285/ijpsn.2020.13.4.9.

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This study was aimed to develop an oral bio-based mucoadhesive polymer from seeds mucilage of Buchanania lanzan spreng, belongs to family anacardiaceae. Isolated mucilage was evaluated for mucoadhesive strength and compared with existing polymer. The mucilage showed shear stress results (0.099 ± 0.0001N), with comparable adhesiveness to methocel E5 (0.098 ± 0.0008N). Force of adhesion required to detach the seed mucilage and methocel E5 tablets from the mucin of intestinal tissue were 0.0276 ± 0.0019 (N) and 0.0049 ± 0.0006 (N), respectively. Seed mucilage revealed significant (P<0.01) high

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Monrroy, Mariel, Erick García, Katherine Ríos, and José Renán García. "Extraction and Physicochemical Characterization of Mucilage from Opuntia cochenillifera (L.) Miller." Journal of Chemistry 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/4301901.

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The aim of this study was to extract mucilage from O. cochenillifera (L.) cacti and determine its functional and physicochemical properties. The best mucilage yield (31%) was obtained by nonthermal extraction with hydration. The mucilage has appreciable carbohydrate and protein contents. The phytochemical analysis shown the presence of alkaloids and terpenes/steroids. The Fourier transformed infrared (FT-IR) spectrum of the mucilage exhibits typical bands for carbohydrates as O–H, C–H, and –COO−. The mucilage demonstrated water- and oil-holding capacities of 2.78 g water/g dry mucilage and 1.8

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Puligundla, Pradeep, and Seokwon Lim. "A Review of Extraction Techniques and Food Applications of Flaxseed Mucilage." Foods 11, no. 12 (2022): 1677. http://dx.doi.org/10.3390/foods11121677.

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Flaxseed contains significant concentration of mucilage or gum (a type of hydrocolloid). Flaxseed mucilage (FM) predominantly occurs in the outermost layer of the seed’s hull and is known to possess numerous health benefits such as delayed gastric emptying, reduced serum cholesterol, and improved glycemic control. FM is typically composed of an arabinoxylan (neutral in nature) and a pectic-like material (acidic in nature). Similar to gum arabic, FM exhibits good water-binding capacity and rheological properties (similar functionality); therefore, FM can be used as its replacement in foods. In

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Prajapati, Vijay, Bhupendra Giri, Suchita Wamankar, Gyanesh Kumar Sahu, and Rajesh Kumar Nema. "An Overview on Isolation & Evaluation of Flaxseed Mucilage and its use as a Pharmaceutical Excipients." International Journal of Advanced Multidisciplinary Research and Studies 5, no. 1 (2025): 143–53. https://doi.org/10.62225/2583049x.2025.5.1.3631.

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Flaxseed contains significant concentration of mucilage or gum (a type of hydrocolloid). Flaxseed mucilage (FM) predominantly occurs in the outermost layer of the seed’s hull and is known to possess numerous health benefits such as delayed gastric emptying, reduced serum cholesterol, and improved glycemic control. FM is typically composed of an arabinoxylan (neutral in nature) and a pectic-like material (acidic in nature). Similar to gum arabic, FM exhibits good water-binding capacity and rheological properties (similar functionality); therefore, FM can be used as its replacement in foods. In

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Arsul, V. A., S. Lahoti, P. K. Sharma, and B. Shrivastava. "EVALUATION OF TRIBULUS TERRESTRIS MUCILAGE AS BINDER IN TABLET FORMULATIONS." INDIAN DRUGS 52, no. 07 (2015): 10–17. http://dx.doi.org/10.53879/id.52.07.10336.

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The aim of this study is to develop an economic and effective natural excipient that can be used as an alternative in formulation of tablets. Tribulus terrestris (Zygophyllaceae) is a herbaceous weed native throughout India and mucilage is derived from the freshly dried and coarsely powdered leaves. phytochemical and physiochemical characteristics of mucilage were studied. Mucilage was used in 5 different concentrations (10, 15, 20, 25, and 30% w/V). Metoprolol tartrate was used as model drug for formulation. The DSC and FTIR of drug and mucilage indicate no chemical interaction. The propertie

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B. Jerad1, Bushra. "EXTRACTION AND CHARACTERATION OF MUCILAGE EXTRACTED FROM MUSTARD SEEDS." iraq journal of market research and consumer protection 13, no. 1 (2021): 55–64. http://dx.doi.org/10.28936/jmracpc13.1.2021.(6).

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The mucilage was isolated from mustard seeds and identification by some different methods like, thermo gravimetric, FTlR., X-ray powdered, proton NMR, FTIR spectra of the three gums contain different functional group in the gums, major peaks bands noticed were belong to OH (3410.15 – 3010.88) group from hydroxyl group, CH aliphatic (2925-2343.51), C-O (1072.42-1060.85) group and C=O 1743.65, Thermo chemical parameters of mucilage was evaluated and compared with the standard gums, Results indicated the mucilage was decomposed in 392°C and mass loss 55%, The X ray process found the mucilage had

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