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1

Pertiwi, Ratih Dyah, Joshita Djajadisastra, ABDUL MUTALIB, and Anung Pujiyanto. "Pembuatan, Karakterisasi dan Uji In Vitro Nanopartikel Emas Berbasis Konjugat Gom Arab-Vinkristin." JURNAL ILMU KEFARMASIAN INDONESIA 16, no. 1 (April 27, 2018): 6. http://dx.doi.org/10.35814/jifi.v16i1.486.

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Gold nanoparticles (AuNP) are potentially developed as nanomedicine because AuNP is easily synthesized, functionalized, and biocompatible. With gum arabic as a stabilizer, vincristine was conjugated with gold nanoparticles. As a reducing agent, it used 0.02 M Natrium Boro Hidrat (NaBH4) solution. Gold nanoparticles (AuNP) coated with conjugated gum Arabic (GA) and vincristine (VCR) were successfully synthesized and characterized. The conjugation of GA-VCR and AuNP displayed a narrow hydrodynamic particle size distribution with average size < 100 nm by TEM and PSA (particle size analyzer). We investigated the cytotoxic activity of conjugated vincristine-gum arabic-gold nanoparticle by tetrazolium salt assay (MTT) using cancer cell line CCR-CEM. Cytotoxic activity of conjugated VCR-GA-AuNP before and after purification by Size Exclusion Chromatography (SEC), against leukemia cell line CCRF-CEM, was described by IC50 value. All formulation had a cytotoxic of activity with IC50 <20 μg/ml. The IC50 of samples against CCRF cell line were 1,026 μg/mL and 2,607 ug/mL, respectively.
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Huseen, Rania Hasan, Ali A. Taha, Ihab Q. Ali, Oday Mahmmod Abdulhusein, and Selma M. H. Al-Jawad. "Biological activity of gum Arabic-coated ferrous oxide nanoparticles." Modern Physics Letters B 35, no. 24 (July 28, 2021): 2150411. http://dx.doi.org/10.1142/s021798492150411x.

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In this study, iron oxide nanoparticles (NPs) had been prepared by co-precipitation method. In order to reduce their toxicity and increase stability, prepared iron oxide was coated with gum Arabic. Gum Arabic is preferred over synthetic materials due to their non-toxicity, low cost and availability. Characterization of coated and non-coated iron oxide NPs had been performed by spectrophotometer, Fourier transfer infra-red spectrophotometer (FTIR), Zeta potential, X-ray diffraction (XRD) and field emission scanning electron microscopic (FE-SEM). The fabricated nanoparticles appeared purity and crystalline nature by XRD, with diameter average of 27.01 nm and 55.12 nm for iron oxide NPs and iron oxide NPs coated with gum Arabic, respectively. On the other hand, four biological activities of coated and non-coated iron oxide had been investigated. High removal of methylene blue pollutant dye (46%) was observed with iron oxide NPs, while removal percentage was 22.6 performed by iron oxide NPs coated with gum Arabic within 72 h. Iron oxide NPs revealed high inhibition zones of 27.5 nm and 30 mm, at 1000 [Formula: see text]g/ml, against S. aureus and E. coli, respectively, while coated iron oxide NPs with gum Arabic revealed low antibacterial activity against both examined bacteria even when used at 1000 [Formula: see text]g/ml. The hemolytic activity of prepared NPs had been determined. The hemolytic percentage was increased whenever concentrations of nanoparticles increased. Lower hemolytic percentages were 69.76 and 50.98 for iron oxide NPs and iron oxide NPs coated with gum Arabic were observed at a concentration of 250 [Formula: see text]g/ml. Finally, cytotoxic activity was estimated against MCF-7 cell line and normal cell line WRL68 by MTT assay. A decrease in MCF-7 viability to 65.1% was observed when 400 [Formula: see text]g/ml of iron oxide NPs was used, while WRL68 viability was 75.03%. Iron oxide NPs coated with gum Arabic revealed significant reduction in MCF-7 and WRL68 viability to 69.90% and 80.05%, respectively, when 400 [Formula: see text]g/ml of nanoparticles was applied.
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3

Roque, A. C. A., and O. C. Wilson. "Adsorption of gum Arabic on bioceramic nanoparticles." Materials Science and Engineering: C 28, no. 3 (April 2008): 443–47. http://dx.doi.org/10.1016/j.msec.2007.04.009.

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4

Williams, Darryl N., Katie A. Gold, Tracey R. Pulliam Holoman, Sheryl H. Ehrman, and Otto C. Wilson. "Surface Modification of Magnetic Nanoparticles Using Gum Arabic." Journal of Nanoparticle Research 8, no. 5 (May 25, 2006): 749–53. http://dx.doi.org/10.1007/s11051-006-9084-7.

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5

Ashraf, Jalaluddin M., Mohammad Azam Ansari, Inho Choi, Haris M. Khan, and Mohammad A. Alzohairy. "Antiglycating Potential of Gum Arabic Capped-Silver Nanoparticles." Applied Biochemistry and Biotechnology 174, no. 1 (July 31, 2014): 398–410. http://dx.doi.org/10.1007/s12010-014-1065-1.

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6

Araujo, Francisca P., Pollyana Trigueiro, Luzia M. C. Honório, Marcelo B. Furtini, Dyego M. Oliveira, Luciano C. Almeida, Ramón R. P. Garcia, Bartolomeu C. Viana, Edson C. Silva-Filho, and Josy A. Osajima. "A novel green approach based on ZnO nanoparticles and polysaccharides for photocatalytic performance." Dalton Transactions 49, no. 45 (2020): 16394–403. http://dx.doi.org/10.1039/d0dt01128b.

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7

Vijayakumar, S., and S. Ganesan. "In VitroCytotoxicity Assay on Gold Nanoparticles with Different Stabilizing Agents." Journal of Nanomaterials 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/734398.

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Noble gold nanoparticles (AuNps) are generally nontoxic due to their inert nature. The gold nanoparticles are easily tagged with various proteins and biomolecules rich in aminoacid leading to important biomedical applications including targeted drug delivery, cellular imaging, and biosensing. In this study, three cytotoxicity detection assays 3-(4,5-dimethylthiozol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT), neutral red cell, and lactate dehydrogenase (LDH) on gold nanoparticles stabilized with citrate, starch, and gum arabic are used. The assays used are based on different mode of detection like LDH release, MTT metabolism, and neutral red uptake. We found that the AuNps stabilized with citrate are very sensitive to the change of concentration and time assay compared to starch and gum arabic stabilized gold nanoparticles.
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8

Alzahrani, Eman. "Gum Arabic-Coated Magnetic Nanoparticles For Methylene Blue Removal." International Journal of Innovative Research in Science, Engineering and Technology 03, no. 08 (August 15, 2014): 15118–29. http://dx.doi.org/10.15680/ijirset.2014.0308009.

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9

Abreu, Flavia Oliveira Monteiro da Silva, Nilvan Alves da Silva, Mateus de Sousa Sipauba, Tamara Fernandes Marques Pires, Tatiana Araújo Bomfim, Oyrton Azevedo de Castro Monteiro Junior, and Maria Madalena de Camargo Forte. "Chitosan and gum arabic nanoparticles for heavy metal adsorption." Polímeros 28, no. 3 (July 10, 2018): 231–38. http://dx.doi.org/10.1590/0104-1428.02317.

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10

Chawla, Prince, Naveen Kumar, Aarti Bains, Sanju Bala Dhull, Mukul Kumar, Ravinder Kaushik, and Sneh Punia. "Gum arabic capped copper nanoparticles: Synthesis, characterization, and applications." International Journal of Biological Macromolecules 146 (March 2020): 232–42. http://dx.doi.org/10.1016/j.ijbiomac.2019.12.260.

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11

Ribeiro de Barros, Heloise, Mateus Borba Cardoso, Carolina Camargo de Oliveira, Célia Regina Cavichiolo Franco, Daniel de Lima Belan, Marcio Vidotti, and Izabel C. Riegel-Vidotti. "Stability of gum arabic-gold nanoparticles in physiological simulated pHs and their selective effect on cell lines." RSC Advances 6, no. 12 (2016): 9411–20. http://dx.doi.org/10.1039/c5ra24858b.

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12

Avadi, M. R., A. M. M. Sadeghi, Naser Mohamadpour Dounighi, R. Dinarvand, F. Atyabi, and M. Rafiee-Tehrani. "Ex Vivo Evaluation of Insulin Nanoparticles Using Chitosan and Arabic Gum." ISRN Pharmaceutics 2011 (July 6, 2011): 1–6. http://dx.doi.org/10.5402/2011/860109.

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Polymeric delivery systems based on nanoparticles have emerged as a promising approach for peroral insulin delivery. The aim of the present study was to investigate the release of insulin nanoparticulate systems and ex vivo studies. The nanoparticles were prepared by the ion gelation method. Particle size distribution, zeta potential, and polydispersity index of the nanoparticles were determined. It was found that the nanoparticles carried positive charges and showed a size distribution in the range of 170–200 nm. The electrostatic interactions between the positively charged group of chitosan and negatively charged groups of Arabic gum play an important role in the association efficiency of insulin in nanoparticles. In vitro insulin release studies showed an initial burst followed by a slow release of insulin. The mucoadhesion of the nanosystem was evaluated using excised rat jejunum. Ex vivo studies have shown a significant increase in absorption of insulin in the presence of chitosan nanoparticles in comparison with free insulin.
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13

Padil, Vinod Vellora Thekkae, Stanisław Wacławek, and Miroslav Černík. "Green Synthesis: Nanoparticles and Nanofibres Based on Tree Gums for Environmental Applications." Ecological Chemistry and Engineering S 23, no. 4 (December 1, 2016): 533–57. http://dx.doi.org/10.1515/eces-2016-0038.

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AbstractThe recent advances and potential applications of nanoparticles and nanofibres for energy, water, food, biotechnology, the environment, and medicine have immensely conversed. The present review describes a ‘green’ method for the synthesis and stabilization of nanoparticles and ‘green electrospinning’ both using tree gums (arabic, tragacanth, karaya and kondagogu). Furthermore, this review focuses on the impending applications of both gum stabilized nanoparticles and functionalized membranes in remediation of toxic metals, radioactive effluents, and the adsorptive removal of nanoparticulates from aqueous environments as well as from industrial effluents. Besides, the antibacterial properties of gum derivatives, gum stabilized nanoparticles, and functionalized electrospun nanofibrous membranes will also be highlighted. The functionalities of nanofibrous membranes that can be enhanced by various plasma treatments (oxygen and methane, respectively) will also be emphasized.
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14

Majeed, Noor Sabeeh, Hussein A. Alabdly, Hussam Nadum Abdalraheem Al Ani, Dumitru Pascu, and Aurelia Cristina Nechifor. "Study the Effect of Gum Arabic and Triton X-100 on Stability and Thermal Conductivity of ZnO/ethylene glycol Nanofluids." Revista de Chimie 72, no. 1 (February 3, 2021): 18–24. http://dx.doi.org/10.37358/rc.21.1.8400.

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Stability of nanofluids is one of the most important factors to ensure the most benefit of the properties of nanoparticles. Zinc oxide was used in the research with concentration between (0.2-1) wt. % with ethylene glycol base fluid. The stability of ZnO nanofluid was enhanced by adding two types of surfactants Tx-100 and Gum Arabic with concentration of (0.1-0.5) vol. % to stabilize the ZnO nanoparticles in the base fluid. The results showed that the Gum Arabic surfactant led to more stable fluid than that of Tx-100; this was shown from zeta potential and UV spectroscopy measurements. The thermal conductivity coefficient was also measured, and the results showed that the thermal conductivity increased with adding surfactant than without using a stabilizer.
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15

Ribeiro de Barros, Heloise, Mateus Borba Cardoso, Carolina Camargo de Oliveira, Célia Regina Cavichiolo Franco, Daniel de Lima Bellan, Marcio Vidotti, and Izabel C. Riegel-Vidotti. "Correction: Stability of gum Arabic-gold nanoparticles in physiological simulated pHs and their selective effect on cell lines." RSC Advances 8, no. 71 (2018): 40596. http://dx.doi.org/10.1039/c8ra90090f.

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16

Wilson, Otto C., Erin Blair, Stephanie Kennedy, Gloryvee Rivera, and Patrick Mehl. "Surface modification of magnetic nanoparticles with oleylamine and gum Arabic." Materials Science and Engineering: C 28, no. 3 (April 2008): 438–42. http://dx.doi.org/10.1016/j.msec.2007.04.008.

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17

LI, Ying-fen, Wei-ping GAN, Jian ZHOU, Zhi-qiang LU, Chao YANG, and Tian-tian GE. "Hydrothermal synthesis of silver nanoparticles in Arabic gum aqueous solutions." Transactions of Nonferrous Metals Society of China 25, no. 6 (June 2015): 2081–86. http://dx.doi.org/10.1016/s1003-6326(15)63818-3.

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18

Roque, Ana C. A., A. Bicho, Iris L. Batalha, Ana S. Cardoso, and Abid Hussain. "Biocompatible and bioactive gum Arabic coated iron oxide magnetic nanoparticles." Journal of Biotechnology 144, no. 4 (December 2009): 313–20. http://dx.doi.org/10.1016/j.jbiotec.2009.08.020.

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19

Kong, Huiling, Jixin Yang, Yifeng Zhang, Yapeng Fang, Katsuyoshi Nishinari, and Glyn O. Phillips. "Synthesis and antioxidant properties of gum arabic-stabilized selenium nanoparticles." International Journal of Biological Macromolecules 65 (April 2014): 155–62. http://dx.doi.org/10.1016/j.ijbiomac.2014.01.011.

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20

Humbatova, Seadet, Shamo Tapdigov, Nizami Zeynalov, Dilgam Taghiyev, and Samira Mammadova. "Synthesis and Study of Structure Silver Nanoparticles by Polyethyleneglycol - Gum Arabic Polymers." Journal of Nano Research 45 (January 2017): 25–33. http://dx.doi.org/10.4028/www.scientific.net/jnanor.45.25.

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Silver nanoparticles were synthesized at 293÷353 K temperature range by NaBH4 and HCOOH solutions with low concentration at polyethyleneglycol having average molecular weight of 40000 and 200 kDa gum arabic medium. Obtained silver nanoparticles were studied using methods of X-ray diffraction, UV-Vis, FTIR spectroscopy, scanning electron microscope. It was determined that sizes of silver nanoparticles which stabilize at polymer medium vary from 12 to 26 nm range depending on mole ratio, temperature and reduction medium of initial substances. It was shown by FTIR-spectroscopy that -OH and -COOH groups in polymer take an active part in stabilization of silver nanoparticles. It was determinated by UV-Vis study of silver nanoparticles containing polymer composition in aqueous condition that 412 nm which is specific to silver atoms do not change sharply for 4-5 days.
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21

Pauzi, Norlin, Norashikin Mat Zain, and Nurul Amira Ahmad Yusof. "Microwave-assisted Synthesis of ZnO Nanoparticles Stabilized with Gum Arabic: Effect of Microwave Irradiation Time on ZnO Nanoparticles Size and Morphology." Bulletin of Chemical Reaction Engineering & Catalysis 14, no. 1 (April 15, 2019): 182. http://dx.doi.org/10.9767/bcrec.14.1.3320.182-188.

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The conventional heating methods of nanoparticle synthesis regularly depend on the energy inputs from outer heat sources that resulted high energy intake and low reaction competences. In this paper ZnO nanoparticles stabilized with gum arabic are synthesized using precipitating method assisted by simple and cost effective microwave heating technique. The objective of this work is to investigate the effect of microwave irradiation time towards ZnO nanoparticles morphology and size. The effect of microwave irradiation time has been investigated at 2, 4, 6, and 10 minutes. Dynamic Light Scattering (DLS) was employed to measure the size of ZnO nanoparticles. Ultraviolet–Visible spectroscopy (UV-vis), Fourier-Transform Infrared Spectroscopy (FTIR) and X-Ray Diffraction (XRD) were used for the characterization of the ZnO nanoparticles. UV-vis absorption spectrum was found in the range of 350 nm indicating the absorption peak of ZnO nanoparticles. FTIR spectra showed peaks range from 424 to 475 cm–1 which indicating standard of Zn–O stretching. The presence of (100), (002), and (101) planes were apparent in the XRD result, indicating the crystalline phase of ZnO nanoparticles. The increase in the microwave irradiation time affected the processes of nucleation and crystal growth promoted larger ZnO nanoparticles size. Microwave irradiation time at 2 minutes was selected as the best microwave irradiation time for smallest ZnO nanoparticles averaging about 168 nm sizes based on DLS analysis. Copyright © 2019 BCREC Group. All rights reservedReceived: 1st October 2018; Revised: 22nd November 2018; Accepted: 12nd December 2018; Available online: 25th January 2019; Published regularly: April 2019How to Cite: Pauzi, N., Zain, N.M., Yusof, N.A.A. (2019). Microwave-assisted Synthesis of ZnO Nanoparticles Stabilized with Gum Arabic: Effect of Microwave Irradiation Time on ZnO Nanoparticles Size and Morphology. Bulletin of Chemical Reaction Engineering & Catalysis, 14 (1): 182-188 (doi:10.9767/bcrec.14.1.3320.182-188)Permalink/DOI: https://doi.org/10.9767/bcrec.14.1.3320.182-188
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Youssef, Ahmed M., Hoda S. El-Sayed, Islam EL-Nagar, and Samah M. El-Sayed. "Preparation and characterization of novel bionanocomposites based on garlic extract for preserving fresh Nile tilapia fish fillets." RSC Advances 11, no. 37 (2021): 22571–84. http://dx.doi.org/10.1039/d1ra03819b.

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In current work a new bionanocomposite based on carboxymethyl cellulose, Arabic gum and gelatin, incorporating garlic extract and TiO2 nanoparticles as an edible coating for preserving the fresh Nile tilapia fish fillets during cold storage.
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Chawla, Prince, Agnieszka Najda, Aarti Bains, Renata Nurzyńska-Wierdak, Ravinder Kaushik, and Mansuri M. Tosif. "Potential of Gum Arabic Functionalized Iron Hydroxide Nanoparticles Embedded Cellulose Paper for Packaging of Paneer." Nanomaterials 11, no. 5 (May 15, 2021): 1308. http://dx.doi.org/10.3390/nano11051308.

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Recently, the interest of scientists has turned towards eco-friendly metal nanoparticles due to their distinctive physicochemical properties that have been used in several biochemical and food applications, including drug and bioactive component delivery, sensing of food pathogenic bacteria, imaging techniques, and theranostics. Therefore, this study aimed to fabricate gum arabic stabilized iron hydroxide nanoparticles (IHNPs) using the co-precipitation process and to develop nanoparticles decorated antimicrobial cellulose paper. The agglomeration of IHNPs is a major concern, therefore, the varied concentration (0.25–2.0%) of gum arabic was used to functionalize and stabilize the nanoparticles, and based on UV-visible spectroscopy and particle size analysis, 1% gum arabic concentration was screened out. Scanning electron microscopy displayed polygonal disc shapes of IHNPs that had sides of approximately equal lengths. Energy dispersive spectroscopy was used to determine the purity of the IHNPs and results illustrated the elemental iron peak at 0.8 keV and 6.34 keV. For thermal stability, differential scanning calorimetry (DSC) was employed, and the glass transition temperature was observed at 138.50 °C with 138.31 °C onset and 147.14 °C endset temperature, respectively. Functionalized IHNPs showed a significantly (p < 0.05) higher zone of inhibition against S. aureus (29.63 mm) than that of E. coli and were found to be non-toxic to Caco-2 cells during cell viability assay. Time-kill kinetics showed that cellulose paper embedded with nanoparticles possessed excellent antibacterial activity against S. aureus. To explore the food application of developed cellulose paper, citric acid coagulated dairy product (Paneer), similar to cottage cheese was formulated, and it was evaluated for its microbial shelf life. The unwrapped sample showed higher microbial load during the fourth day of the storage. However, both wrapped samples were acceptable till the 10th of storage.
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Fardood, Saeid Taghavi, Ali Ramazani, and Sajjad Moradi. "A Novel Green Synthesis of Nickel Oxide Nanoparticles Using Arabic Gum." Chemistry Journal of Moldova 12, no. 1 (May 2017): 115–18. http://dx.doi.org/10.19261/cjm.2017.383.

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Appolonia Ibekwe, Chinenye, Grace Modupe Oyatogun, Temitope Ayodeji Esan, and Kunle Michael Oluwasegun. "Synthesis and Characterization of Chitosan/Gum Arabic Nanoparticles for Bone Regeneration." American Journal of Materials Science and Engineering 5, no. 1 (September 17, 2017): 28–36. http://dx.doi.org/10.12691/ajmse-5-1-4.

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Batalha, Iris L., Abid Hussain, and A. C. A. Roque. "Gum Arabic coated magnetic nanoparticles with affinity ligands specific for antibodies." Journal of Molecular Recognition 23, no. 5 (January 29, 2010): 462–71. http://dx.doi.org/10.1002/jmr.1013.

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Gils, Palapparambil Sunny, Debajyoti Ray, and Prafulla Kumar Sahoo. "Designing of silver nanoparticles in gum arabic based semi-IPN hydrogel." International Journal of Biological Macromolecules 46, no. 2 (March 2010): 237–44. http://dx.doi.org/10.1016/j.ijbiomac.2009.12.014.

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28

Kazimierczak, Honorata, Krzysztof Szymkiewicz, Eliezer Gileadi, and Noam Eliaz. "The Effect of Direct and Pulsed Current in the Presence of Surfactants on the Electrodeposition of Zn–SiC Nanocomposite Coatings." Coatings 9, no. 2 (February 3, 2019): 93. http://dx.doi.org/10.3390/coatings9020093.

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Zn–SiC nanocomposite coatings were electrodeposited from aqueous citrate electrolytes using either direct current deposition (DCD) or pulsed electrodeposition (PED). The effects of various surface-active organic compounds (SDS, gum arabic, gelatin, CTAB, PEG 20000, and Triton X–100) on the coatings’ surface morphology and chemical composition were studied. The influence of pulse frequency and duty cycle on the percentage of the SiC nanoparticles (NPs) incorporated and on the quality of the deposits was also investigated. The amount of SiC NPs incorporated in the Zn matrix was similar for layers obtained by DCD compared to PED. The Zn–SiC coating deposited by PED exhibited a more fine-grained surface morphology. The percentage of SiC co-deposited with Zn was mainly affected by the type of surfactant used. The ionic surfactants (cationic gelatin and CTAB or anionic gum arabic) allowed the co-deposition of considerably higher amounts of SiC NPs with Zn, compared to the non-ionic compounds PEG 20000 and Triton X–100. However, the use of high molecular weight organic compounds such as gelatin and gum arabic led to aggregation of SiC NPs within the Zn matrix.
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Leong, Kin Yuen, Ibnorita Che Ibrahim, Noor Hafizah Amer, and M. S. Risby. "Thermal Conductivity of Carbon Nanotube Based Nanofluids as Heat Transfer Fluids." Applied Mechanics and Materials 819 (January 2016): 29–33. http://dx.doi.org/10.4028/www.scientific.net/amm.819.29.

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Conventional heat transfer fluids such as water and ethylene glycol exhibit low thermal conductivity. These fluids have certain influences on the efficiency of the thermal system. Efficiency of the thermal system is dependent on the thermal conductivity of the heat transfer fluid. New generation of heat transfer fluid such as nanofluid has potential to address this major problem. Therefore in this study, the thermal conductivity characteristic and stability of multiwalled carbon nanotube based water nanofluids was investigated. Two types of surfactants namely gum arabic and sodium dodecylbenzene sulphate (SDBS) were used to stabilize the nanofluid. Findings implied that thermal conductivity of water increases with the loading of multiwalled carbon nanotube nanoparticles. As for the stability, study shows that nanofluids added with SDBS are more stable compared to that of samples with gum Arabic.
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Eskandari-Nojehdehi, Maryam, Hoda Jafarizadeh-Malmiri, and Abbas Jafarizad. "Microwave Accelerated Green Synthesis of Gold Nanoparticles Using Gum Arabic and their Physico-Chemical Properties Assessments." Zeitschrift für Physikalische Chemie 232, no. 3 (March 28, 2018): 325–43. http://dx.doi.org/10.1515/zpch-2017-1001.

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AbstractMicrowave enhanced gold nanoparticles (Au NPs) were synthesized using gum Arabic as both reducing and stabilizing agents. Response surface methodology was applied to study effects of the Au NPs synthesized parameters, namely, microwave exposure time (90–180 s) and the amount of AgNO3solution (1–10 mL) on the mean particle size, mixture solution color and concentration of the synthesized Au NPs. The colloidal solution containing well-dispersed and spherical fabricated Au NPs with mean particle size (22 nm) and maximum concentration (159 ppm) and color (1.12 absorbance unit, a.u.), were obtained at the optimal synthesis conditions, using 8.17 mL of HAuCl4(1 mM) and 2 mL of gum Arabic solution (4% w/v) during microwave exposure time of 180 s. The physico-chemical properties of the synthesized Au NPs at obtained optimum synthesis conditions were characterized by Fourier transform-infrared spectroscopy, UV-Vis spectroscopy, dynamic light scattering, X-ray diffraction, transmission electron microscopy and field emission scanning electron microscopy.
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Kędzierska, Magdalena, Piotr Potemski, Anna Drabczyk, Sonia Kudłacik-Kramarczyk, Magdalena Głąb, Beata Grabowska, Dariusz Mierzwiński, and Bożena Tyliszczak. "The Synthesis Methodology of PEGylated Fe3O4@Ag Nanoparticles Supported by Their Physicochemical Evaluation." Molecules 26, no. 6 (March 20, 2021): 1744. http://dx.doi.org/10.3390/molecules26061744.

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Many investigations are currently being performed to develop the effective synthesis methodology of magnetic nanoparticles with appropriately functionalized surfaces. Here, the novelty of the presented work involves the preparation of nano-sized PEGylated Fe3O4@Ag particles, i.e., the main purpose was the synthesis of magnetic nanoparticles with a functionalized surface. Firstly, Fe3O4 particles were prepared via the Massart process. Next, Ag+ reduction was conducted in the presence of Fe3O4 particles to form a nanosilver coating. The reaction was performed with arabic gum as a stabilizing agent. Sound energy-using sonication was applied to disintegrate the particles’ agglomerates. Next, the PEGylation process aimed at the formation of a coating on the particles’ surface using PEG (poly(ethylene glycol)) has been performed. It was proved that the arabic gum limited the agglomeration of nanoparticles, which was probably caused by the steric effect caused by the branched compounds from the stabilizer that adsorbed on the surface of nanoparticles. This effect was also enhanced by the electrostatic repulsions. The process of sonication caused the disintegration of aggregates. Formation of iron (II, III) oxide with a cubic structure was proved by diffraction peaks. Formation of a nanosilver coating on the Fe3O4 nanoparticles was confirmed by diffraction peaks with 2θ values 38.15° and 44.35°. PEG coating on the particles’ surface was proven via FT-IR (Fourier Transform Infrared Spectroscopy) analysis. Obtained PEG–nanosilver-coated Fe3O4 nanoparticles may find applications as carriers for targeted drug delivery using an external magnetic field.
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Spasojević, Ljiljana, Sandra Bučko, Davor Kovačević, Klemen Bohinc, Jasmina Jukić, Anže Abram, Josip Požar, and Jaroslav Katona. "Interactions of zein and zein/rosin nanoparticles with natural polyanion gum arabic." Colloids and Surfaces B: Biointerfaces 196 (December 2020): 111289. http://dx.doi.org/10.1016/j.colsurfb.2020.111289.

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Wu, Weihao, Xiangzhen Kong, Caimeng Zhang, Yufei Hua, and Yeming Chen. "Improving the stability of wheat gliadin nanoparticles – Effect of gum arabic addition." Food Hydrocolloids 80 (July 2018): 78–87. http://dx.doi.org/10.1016/j.foodhyd.2018.01.042.

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34

Elbeshir, E. I. A. "On the gum arabic to improve the thermal properties of Fe3O4 nanoparticles." AIP Advances 11, no. 4 (April 1, 2021): 045224. http://dx.doi.org/10.1063/5.0044472.

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AbouAitah, Khaled, Agata Stefanek, Iman M. Higazy, Magdalena Janczewska, Anna Swiderska-Sroda, Agnieszka Chodara, Jacek Wojnarowicz, et al. "Effective Targeting of Colon Cancer Cells with Piperine Natural Anticancer Prodrug Using Functionalized Clusters of Hydroxyapatite Nanoparticles." Pharmaceutics 12, no. 1 (January 16, 2020): 70. http://dx.doi.org/10.3390/pharmaceutics12010070.

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Targeted drug delivery offers great opportunities for treating cancer. Here, we developed a novel anticancer targeted delivery system for piperine (Pip), an alkaloid prodrug derived from black pepper that exhibits anticancer effects. The tailored delivery system comprises aggregated hydroxyapatite nanoparticles (HAPs) functionalized with phosphonate groups (HAP-Ps). Pip was loaded into HAPs and HAP-Ps at pH 7.2 and 9.3 to obtain nanoformulations. The nanoformulations were characterized using several techniques and the release kinetics and anticancer effects investigated in vitro. The Pip loading capacity was >20%. Prolonged release was observed with kinetics dependent on pH, surface modification, and coating. The nanoformulations fully inhibited monolayer HCT116 colon cancer cells compared to Caco2 colon cancer and MCF7 breast cancer cells after 72 h, whereas free Pip had a weaker effect. The nanoformulations inhibited ~60% in HCT116 spheroids compared to free Pip. The Pip-loaded nanoparticles were also coated with gum Arabic and functionalized with folic acid as a targeting ligand. These functionalized nanoformulations had the lowest cytotoxicity towards normal WI-38 fibroblast cells. These preliminary findings suggest that the targeted delivery system comprising HAP aggregates loaded with Pip, coated with gum Arabic, and functionalized with folic acid are a potentially efficient agent against colon cancer.
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36

Balantrapu, Krishna, and Dan V. Goia. "Silver nanoparticles for printable electronics and biological applications." Journal of Materials Research 24, no. 9 (September 2009): 2828–36. http://dx.doi.org/10.1557/jmr.2009.0336.

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An environmentally friendly route to prepare stable concentrated aqueous dispersions of silver nanoparticles is described. It was found that Arabic gum, a well known stabilizing agent, can also rapidly and completely reduce Ag2O to metallic silver in alkaline solutions (pH > 12.0) and elevated temperature (65 °C). The average size of the silver nanoparticles could be tailored from 10 to 30 nm by varying the experimental conditions. By hydrolyzing either enzymatically or chemically the polysaccharide, it was possible to isolate dispersed silver nanoparticles suitable for both biological and printable electronics applications. For the latter purpose, concentrated dispersions of silver particles were prepared and used for depositing thin uniform layers, which could be sintered into conductive films at low temperatures.
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Bicho, Ana, Ana Cecília A. Roque, Ana Sofia Cardoso, Patrícia Domingos, and Íris Luz Batalha. "In vitro studies with mammalian cell lines and gum arabic-coated magnetic nanoparticles." Journal of Molecular Recognition 23, no. 6 (October 28, 2010): 536–42. http://dx.doi.org/10.1002/jmr.1066.

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Ye, Aiqian, John Flanagan, and Harjinder Singh. "Formation of stable nanoparticles via electrostatic complexation between sodium caseinate and gum arabic." Biopolymers 82, no. 2 (2006): 121–33. http://dx.doi.org/10.1002/bip.20465.

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Chockalingam, Ashwin, Heman Babu, Raghuraman Chittor, and Jai Tiwari. "Gum arabic modified Fe3O4 nanoparticles cross linked with collagen for isolation of bacteria." Journal of Nanobiotechnology 8, no. 1 (2010): 30. http://dx.doi.org/10.1186/1477-3155-8-30.

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Dai, Lei, Cuixia Sun, Yang Wei, Like Mao, and Yanxiang Gao. "Characterization of Pickering emulsion gels stabilized by zein/gum arabic complex colloidal nanoparticles." Food Hydrocolloids 74 (January 2018): 239–48. http://dx.doi.org/10.1016/j.foodhyd.2017.07.040.

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41

Gamal-Eldeen, Amira M., Houry M. Baghdadi, Nermeen S. Afifi, Ebtehal M. Ismail, Walaa F. Alsanie, Fayez Althobaiti, and Bassem M. Raafat. "Gum arabic-encapsulated gold nanoparticles modulate hypoxamiRs expression in tongue squamous cell carcinoma." Molecular & Cellular Toxicology 17, no. 2 (January 26, 2021): 111–21. http://dx.doi.org/10.1007/s13273-021-00117-w.

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42

Banerjee, Shashwat S., and Dong-Hwang Chen. "Glucose-Grafted Gum Arabic Modified Magnetic Nanoparticles: Preparation and Specific Interaction with Concanavalin A." Chemistry of Materials 19, no. 15 (July 2007): 3667–72. http://dx.doi.org/10.1021/cm070461k.

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Renuga Devi, P., C. Senthil Kumar, P. Selvamani, N. Subramanian, and K. Ruckmani. "Synthesis and characterization of Arabic gum capped gold nanoparticles for tumor-targeted drug delivery." Materials Letters 139 (January 2015): 241–44. http://dx.doi.org/10.1016/j.matlet.2014.10.010.

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Hassani, A., S. A. Hussain, H. H. Enezei, S. Saeed, W. N. Ibrahim, M. S. Al-Qubaisi, H. Zentou, R. Rosli, and A. A. Doolaanea. "Formulation and antioxidant properties of curcumin gum Arabic nanoparticles for delivery to cancer cells." IOP Conference Series: Materials Science and Engineering 991 (December 22, 2020): 012101. http://dx.doi.org/10.1088/1757-899x/991/1/012101.

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Ba-Abbad, Muneer M., Mohd S. Takriff, Abdelbaki Benamor, Ebrahim Mahmoudi, and Abdul Wahab Mohammad. "Arabic gum as green agent for ZnO nanoparticles synthesis: properties, mechanism and antibacterial activity." Journal of Materials Science: Materials in Electronics 28, no. 16 (May 2, 2017): 12100–12107. http://dx.doi.org/10.1007/s10854-017-7023-2.

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Tan, Chen, Jiehong Xie, Xiaoming Zhang, Jibao Cai, and Shuqin Xia. "Polysaccharide-based nanoparticles by chitosan and gum arabic polyelectrolyte complexation as carriers for curcumin." Food Hydrocolloids 57 (June 2016): 236–45. http://dx.doi.org/10.1016/j.foodhyd.2016.01.021.

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Hu, Qiaobin, Taoran Wang, Mingyong Zhou, Jingyi Xue, and Yangchao Luo. "Formation of redispersible polyelectrolyte complex nanoparticles from gallic acid-chitosan conjugate and gum arabic." International Journal of Biological Macromolecules 92 (November 2016): 812–19. http://dx.doi.org/10.1016/j.ijbiomac.2016.07.089.

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Jafarizad, Abbas, Khadijeh Safaee, and Duygu Ekinci. "Green Synthesis of Gold Nanoparticles Using Aqueous Extracts of Ziziphus jujuba and Gum arabic." Journal of Cluster Science 28, no. 5 (June 30, 2017): 2765–77. http://dx.doi.org/10.1007/s10876-017-1258-1.

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Ibrahim, Mayza, Michal Krejčík, Karel Havlíček, Stanislav Petrík, and Mohamed Eldessouki. "Evaluation of chemical and physical properties of biodegradable gum Arabic/PVA/Ag nanofibrous membranes as a potential wrapping material." Journal of Engineered Fibers and Fabrics 15 (January 2020): 155892502094645. http://dx.doi.org/10.1177/1558925020946451.

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There is a growing public interest in utilizing biomass and biomaterials to obtain products with high sustainability and less harm to the environment. This study reports on using electrospinning technique to produce nanofiber membranes based on homogeneous polymeric blends of gum Arabic, polyvinyl alcohol, and silver nanoparticles. The produced interconnected membranes were cross-linked via heat and plasma treatments, and the membranes were characterized for their chemical and physical characteristics. Fourier transform infrared spectroscopy shows a cross-linking of gum Arabic and polyvinyl alcohol through esterification during the heat treatment, and through graft polymerization with methyl groups after methane plasma treatment. The mechanical performance of the membranes showed an increase in the modulus of elasticity in the longitudinal direction (parallel to electrospun nanofibers) from 85 ± 4 MPa to 148 ± 5 MPa compared with the transverse direction. Also, well-dispersed nanoparticles in the spinning solution tend to increase the elasticity from 41 ± 3 MPa to 148 ± 5 MPa, while the agglomeration of these nanoparticles decreases the mechanical properties of the nanofibers. Results of the biodegradation tests confirmed the significant biodegradable nature of the produced nanofibers, where 99.09% of the material was degraded within 28 days. Moreover, samples showed significant bactericidal activity against Micrococcus luteus with significantly less-observed bacteria in the measured plate, while the inhibition zone for Escherichia coli was 1 cm. The produced biodegradable electrospun membranes have multiple potential applications in many fields; especially for medical, antibacterial, and food packaging. This work reports the results for moisture and oxygen transfer of the membranes as a proposed application in food wrapping.
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Hassani, Abdelkader, Syed Mahmood, Hamid Hammad Enezei, Siti Aslina Hussain, Hamad Ali Hamad, Ahmed Faris Aldoghachi, Abdullah Hagar, Abd Almonem Doolaanea, and Wisam Nabeel Ibrahim. "Formulation, Characterization and Biological Activity Screening of Sodium Alginate-Gum Arabic Nanoparticles Loaded with Curcumin." Molecules 25, no. 9 (May 10, 2020): 2244. http://dx.doi.org/10.3390/molecules25092244.

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The approach of drug delivery systems emphasizes the use of nanoparticles as a vehicle, offering the optional property of delivering drugs as a single dose rather than in multiple doses. The current study aims to improve antioxidant and drug release properties of curcumin loaded gum Arabic-sodium alginate nanoparticles (Cur/ALG-GANPs). The Cur/ALG-GANPs were prepared using the ionotropic gelation technique and further subjected to physico-chemical characterization using attenuated total reflectance–Fourier transform infrared (ATR-FTIR), X-ray diffractometry (XRD), differential scanning calorimetry (DSC), size distribution, and transmission electron microscopy (TEM). The size of Cur/ALG-GANPs ranged between 10 ± 0.3 nm and 190 ± 0.1 nm and the zeta potential was –15 ± 0.2 mV. The antioxidant study of Cur/ALG-GANPs exhibited effective radical scavenging capacity for 1,1-diphenyl-2-picrylhydrazyl (DPPH) at concentrations that ranged between 30 and 500µg/mL. Cytotoxicity was performed using MTT assay to measure their potential in inhibiting the cell growth and the result demonstrated a significant anticancer activity of Cur/ALG-GANPs against human liver cancer cells (HepG2) than in colon cancer (HT29), lung cancer (A549) and breast cancer (MCF7) cells. Thus, this study indicates that Cur/ALG-GANPs have promising anticancer properties that might aid in future cancer therapy.
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