Academic literature on the topic 'Gut-brain axis. Microbial diversity'

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Journal articles on the topic "Gut-brain axis. Microbial diversity"

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Kerstens, Rebecca, Yong Zhi Ng, Sven Pettersson, and Anusha Jayaraman. "Balancing the Oral–Gut–Brain Axis with Diet." Nutrients 16, no. 18 (2024): 3206. http://dx.doi.org/10.3390/nu16183206.

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Background: The oral microbiota is the second largest microbial community in humans. It contributes considerably to microbial diversity and health effects, much like the gut microbiota. Despite physical and chemical barriers separating the oral cavity from the gastrointestinal tract, bidirectional microbial transmission occurs between the two regions, influencing overall host health. Method: This review explores the intricate interplay of the oral–gut–brain axis, highlighting the pivotal role of the oral microbiota in systemic health and ageing, and how it can be influenced by diet. Results: R
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Cryan, John F., Kenneth J. O'Riordan, Caitlin S. M. Cowan, et al. "The Microbiota-Gut-Brain Axis." Physiological Reviews 99, no. 4 (2019): 1877–2013. http://dx.doi.org/10.1152/physrev.00018.2018.

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The importance of the gut-brain axis in maintaining homeostasis has long been appreciated. However, the past 15 yr have seen the emergence of the microbiota (the trillions of microorganisms within and on our bodies) as one of the key regulators of gut-brain function and has led to the appreciation of the importance of a distinct microbiota-gut-brain axis. This axis is gaining ever more traction in fields investigating the biological and physiological basis of psychiatric, neurodevelopmental, age-related, and neurodegenerative disorders. The microbiota and the brain communicate with each other
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Mehnaz, Khan, Ahmad Sharique, and D. Pratap Pushpendra. "Microbial dysbiosis and associated human diseases." GSC Advanced Research and Reviews 20, no. 2 (2024): 021–35. https://doi.org/10.5281/zenodo.14948624.

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Dysbiosis, a disturbance in the normal balance of microbial communities within the body, particularly the gut, is linked to various diseases. The human microbiota is essential for health, aiding digestion, synthesizing vitamins, modulating the immune system, and protecting against pathogens. Dysbiosis can result from factors like antibiotic use, dietary changes, infections, and chronic diseases, potentially leading to or worsening multiple health conditions. Gastrointestinal diseases are prominently associated with dysbiosis, Conditions such as inflammatory bowel disease (IBD), irritable bowel
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De Sales-Millán, Amapola, José Félix Aguirre-Garrido, Rina María González-Cervantes, and José Antonio Velázquez-Aragón. "Microbiome–Gut–Mucosal–Immune–Brain Axis and Autism Spectrum Disorder (ASD): A Novel Proposal of the Role of the Gut Microbiome in ASD Aetiology." Behavioral Sciences 13, no. 7 (2023): 548. http://dx.doi.org/10.3390/bs13070548.

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Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterised by deficits in social interaction and communication, as well as restricted and stereotyped interests. Due of the high prevalence of gastrointestinal disorders in individuals with ASD, researchers have investigated the gut microbiota as a potential contributor to its aetiology. The relationship between the microbiome, gut, and brain (microbiome–gut–brain axis) has been acknowledged as a key factor in modulating brain function and social behaviour, but its connection to the aetiology of ASD is not well understo
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Chidambaram, Saravana Babu, Annan Gopinath Rathipriya, Arehally M. Mahalakshmi, et al. "The Influence of Gut Dysbiosis in the Pathogenesis and Management of Ischemic Stroke." Cells 11, no. 7 (2022): 1239. http://dx.doi.org/10.3390/cells11071239.

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Recent research on the gut microbiome has revealed the influence of gut microbiota (GM) on ischemic stroke pathogenesis and treatment outcomes. Alterations in the diversity, abundance, and functions of the gut microbiome, termed gut dysbiosis, results in dysregulated gut–brain signaling, which induces intestinal barrier changes, endotoxemia, systemic inflammation, and infection, affecting post-stroke outcomes. Gut–brain interactions are bidirectional, and the signals from the gut to the brain are mediated by microbially derived metabolites, such as trimethylamine N-oxide (TMAO) and short-chain
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Long, Emily S., Beatriz Penalver Bernabe, Kai Xia, et al. "The microbiota-gut-brain axis and perceived stress in the perinatal period." Archives of Women's Mental Health 26, no. 2 (2023): 227–34. http://dx.doi.org/10.1007/s00737-023-01300-9.

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Abstract Perinatal perceived stress can contribute to worse health outcomes for the parent–child dyad. Given the emerging relationship between the microbiota-gut-brain axis and stress, this study sought to elucidate connections between bowel symptoms and the gut microbiome in relation to perceived stress at three time points in the perinatal period: two during pregnancy and one postpartum. Ninety-five pregnant individuals participated in a prospective cohort study from April 2017 to November 2019. Researchers assessed Perceived Stress Scale-10 (PSS); bowel symptoms (according to the IBS Questi
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Zhang, Li, Renhe Liu, Zheyi Song, and Xin Zhang. "Exercise, Diet, and Brain Health: From the Perspective of Gut Microbiota Regulation." Nutrients 17, no. 10 (2025): 1686. https://doi.org/10.3390/nu17101686.

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The existing body of evidence has highlighted gut microbiota as a versatile regulator of body wellness affecting not only multiple physiological metabolisms but also the function of remote organs. Emerging studies revealed a reciprocal relationship between physical exercise and intestinal microbiota, suggesting that physical exercise could enhance gut health, including regulating intestinal barrier integrity, increasing microbial diversity, and promoting beneficial microbial metabolism. Furthermore, the beneficial outcomes of exercise on the intestine may also promote brain health through the
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Anand, Nikhilesh, Vasavi Rakesh Gorantla, and Saravana Babu Chidambaram. "The Role of Gut Dysbiosis in the Pathophysiology of Neuropsychiatric Disorders." Cells 12, no. 1 (2022): 54. http://dx.doi.org/10.3390/cells12010054.

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Mounting evidence shows that the complex gut microbial ecosystem in the human gastrointestinal (GI) tract regulates the physiology of the central nervous system (CNS) via microbiota and the gut–brain (MGB) axis. The GI microbial ecosystem communicates with the brain through the neuroendocrine, immune, and autonomic nervous systems. Recent studies have bolstered the involvement of dysfunctional MGB axis signaling in the pathophysiology of several neurodegenerative, neurodevelopmental, and neuropsychiatric disorders (NPDs). Several investigations on the dynamic microbial system and genetic–envir
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Santos, João Víctor Ferreira, and Mariana Heyden Barbosa. "ROLE OF MICROBIOTA-GUT-BRAIN AXIS IN AUTISM SPECTRUM DISORDER." International Seven Journal of Health Research 4, no. 2 (2025): 102–13. https://doi.org/10.56238/isevjhv4n2-003.

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Background: This narrative literature review shows a close link between autism spectrum disorder and the severity of gastrointestinal symptoms, as there is a two-way communicative linking known as the gut-brain axis, and a large amount of research shows the importance of a balanced microbiota to guarantee normal development and sustainment of brain function. Methods: A systematic review was performed utilizing the PubMed (Medline) database to explore literature published within the last 6 years, focusing on studies investigating the correlation between the gut-brain axis and autism spectrum di
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Rea, Kieran, Siobhain M. O' Mahony, Timothy G. Dinan, and John F. Cryan. "Visceral pain: role of the microbiome-gut-brain axis." Biochemist 39, no. 2 (2017): 6–9. http://dx.doi.org/10.1042/bio03902006.

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A growing body of preclinical and clinical evidence supports a relationship between the complexity and diversity of the microorganisms that inhabit our gut (human gastrointestinal microbiome) and health status. These microbes can influence centrally regulated emotional behaviour through mechanisms including microbially derived bioactive molecules, mucosal immune and enteroendocrine cell activation, as well as vagal nerve stimulation. Changes to the microbial environment, as a consequence of illness, stress or injury can lead to a broad spectrum of local physiological and behavioural effects in
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Dissertations / Theses on the topic "Gut-brain axis. Microbial diversity"

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Cobb, Christina. "A Link Between Gut Microbes & Depression: Microbial Activation of the Human Kynurenine Pathway." Scholarship @ Claremont, 2018. http://scholarship.claremont.edu/cmc_theses/1799.

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Our gut microbiota is involved in human development, nutrition, and the pathogenesis of gut disorders, but has more recently been implicated as a possible mechanism in the pathophysiology of several brain disorders, including disorders of mood and affect, such as depression. Researchers have referred to this dynamic, bidirectional signaling pathway between the gut and the brain as the “gut-brain axis.” However, most research on this axis has been limited to rodent studies, and there has been little insight into the mechanism behind it. I propose that the kynurenine pathway, where tryptophan is
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Lisko, Daniel Joseph. "The Effect of Probiotics on Human Gastrointestinal Microbial Communities." Youngstown State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1442437599.

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Books on the topic "Gut-brain axis. Microbial diversity"

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Lyte, Mark, and John F. Cryan, eds. Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0897-4.

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Lyte, Mark, and J. F. Cryan. Microbial endocrinology: The microbiota-gut-brain axis in health and disease. Springer, 2014.

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Lyte, Mark, and John F. Cryan. Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease. Springer, 2016.

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Book chapters on the topic "Gut-brain axis. Microbial diversity"

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Gupta, Chamma, Abhishek Byahut, Chandrali Deka, Arundhati Bag, and Bidita Khandelwal. "The Gut-Brain Axis and the Human Microbiome." In Microbial Ecology. CRC Press, 2024. http://dx.doi.org/10.1201/9781003399247-3.

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Mayekar, Kshitij, Tanmayee Joshi, Rohini Waghmare, and Ginpreet Kaur. "Microbial Modulation of Gut–Brain Axis: Implications for Mental Health." In Gut Microbiota. Jenny Stanford Publishing, 2025. https://doi.org/10.1201/9781003596844-8.

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Lyte, Mark. "Microbial Endocrinology and the Microbiota-Gut-Brain Axis." In Advances in Experimental Medicine and Biology. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0897-4_1.

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Jain, Pranay, Ram Kumar Pundir, and Ram Prakash Pandey. "Exploring the Impact of Microbial Invasion on the Diseases Involving Gut-Brain Axis in Animals." In Livestock Diseases and Management. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-2209-3_11.

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Ledo, A., B. S. Rocha, and J. Laranjinha. "Bioactive Lipids and the Gut-Brain Axis: Diet as a Modulator of Bioactivity and Diversity of Lipids in the Brain." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-11488-6_10.

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Upaganlawar, Aman Babanrao, Nitu Wankhede, Mayur Kale, et al. "Microbiome and Brain-Gut Microbiota's Influence on Autism Pathogenesis." In Empowering Innovations in Advanced Autism Research and Management. IGI Global, 2025. https://doi.org/10.4018/979-8-3693-8176-2.ch004.

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Autism Spectrum Disorders (ASD) are neurodevelopmental conditions characterized by social communication challenges and repetitive behaviors. Emerging evidence suggests that gut microbiota, through the gut-brain axis, play a significant role in ASD pathogenesis. This complex communication network influences neurodevelopment by modulating immune responses, producing neuroactive metabolites, and maintaining gut barrier integrity. In individuals with ASD, specific microbial imbalances and reduced diversity are commonly observed, which are linked to these pathophysiological processes. Genetic predi
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Bucurica, Sandica. "Microbiota Involvement in Acute and Chronic Pancreatitis." In Acute and Chronic Pancreatitis [Working Title]. IntechOpen, 2024. https://doi.org/10.5772/intechopen.1008326.

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The microbiota plays a significant role in the development, progression, and severity of both acute and chronic pancreatitis through mechanisms involving immune modulation, microbial translocation, and gut permeability. The intricate relationship between gut microbiota and pancreatitis reveals distinct mechanisms through which acute and chronic forms of the disease manifest. In acute pancreatitis, microbial dysbiosis leads to significant alterations in gut flora, characterized by reduced diversity and an overrepresentation of pathogenic bacteria. This dysbiosis is associated with compromised g
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Kature, Dattatraya, Vikesh Kukade, and Rajendra Patil. "FECAL MICROBIOTA TRANSPLANTATION IN ASTHMA." In Futuristic Trends in Chemical Material Sciences & Nano Technology Volume 3 Book 5. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3becs5p1ch4.

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Asthma is a chronic lung disease that affects people of all ages and is expected to affect 400 million people by 2025, with over 250,000 deaths recorded each year and enormous health-care costs. Chronic inflammation causes airway hyper responsiveness, which results in recurring episodes of wheezing, dyspnea, chest tightness, and/or coughing that increase in frequency and intensity over time. Although the pathophysiology of asthma is unknown, it has been linked to a variety of genetic, environmental, viral, and dietary factors. Asthma has been linked to microbial triggers in the gut as a major
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Westfall, Susan, Duy M. Dinh, and Giulio Maria Pasinetti. "Investigation of Potential Brain Microbiome in Alzheimer’s Disease: Implications of Study Bias." In Advances in Alzheimer’s Disease. IOS Press, 2022. http://dx.doi.org/10.3233/aiad220004.

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Background: Dysbiotic microbiota in the gastrointestinal tract promotes and aggravates neurodegenerative disorders. Alzheimer’s disease (AD) has been shown to correlate to dysbiotic bacteria and the immune, metabolic, and endocrine abnormalities associated with abnormal gut-brain-axis signaling. Recent reports also indicate that brain dysbacteriosis may play a role in AD pathogenesis. Objective: To evaluate the presence and differences of brain-region dependent microbiomes in control and AD subjects and the contribution of study bias. Methods: Two independent cohorts of postmortem AD brain sam
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Lyte, M. "Microbial Endocrinology." In The Gut-Brain Axis. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-12-802304-4.00006-2.

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Conference papers on the topic "Gut-brain axis. Microbial diversity"

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Ahmed, Saad, Zackary Harris, and Russell David Levi. "Relationship Between Gut Microbiota and Dementia." In 28th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2024. http://dx.doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.90_2024.

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This paper explores the complex relationship between gut microbiota, dietary habits, and dementia, focusing particularly on Alzheimer's disease (AD). Growing evidence suggests a significant link between the composition of gut bacteria, dietary choices, and susceptibility to dementia. Notably, individuals with dementia demonstrate a noticeable reduction in gut bacteria diversity, highlighting the crucial role of a balanced microbiome in maintaining cognitive health. Conversely, dietary preferences characterized by excessive consumption of processed foods and sugars are associated with an increa
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Nogueira, Fábio Dias, Ana Klara Rodrigues Alves, Barbara Beatriz Lira da Silva, et al. "The autistic spectrum disorder and its relation to intestinal dysbiosis." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.283.

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Introduction: Autistic Spectrum Disorder (ASD) is characterized by a neurodevelopmental disorder, in which the child has persistent deficits in verbal and / or non-verbal communication, social interaction and behavior. One of the factors related to the cause of ASD are nutritional aspects, such as intestinal dysbiosis. Objective: To analyze the relationship between imbalance in the intestinal microbiota and the pathophysiological characteristics of ASD. Methodology: This is a systematic review, carried out in the Pubmed, SciELO databases, in order to answer the question: what is the relationsh
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