Academic literature on the topic 'H‐insertion reaction'

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Journal articles on the topic "H‐insertion reaction"

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Calter, Michael A. "Transition Metal-Catalyzed, Asymmetric Reactions of Diazo Compounds." Current Organic Chemistry 1, no. 1 (1997): 37–70. http://dx.doi.org/10.2174/1385272801666220121184444.

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The past ten years have seen impressive advances in asymmetric synthesis. This review summarizes the recent advances in a particular set of asymmetric reactions, the reactions of diazo compounds catalyzed by transition metal complexes. Additionally, the emphasis of this summary is on reactions wherein the induction arises from a catalyst or an auxiliary, rather than some inherent asymmetry of the substrate. The covered reactions fall into two reaction types; cyclopropanations and insertions. The cyclopropanation section of this review describes how high stereoselectivities are possible using e
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YAN, BING-FEI, WEN-ZUO LI, YU-WEI PEI, QING-ZHONG LI, and JIAN-BO CHENG. "THEORETICAL INVESTIGATION ON THE INSERTION REACTIONS OF THE GERMYLENOIDH2GeLiFWITHRH(R=Cl,SH,PH2)." Journal of Theoretical and Computational Chemistry 12, no. 03 (2013): 1350003. http://dx.doi.org/10.1142/s021963361350003x.

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The insertion reactions of the germylenoid H2GeLiF with RH (R = Cl, SH , PH2) were studied for the first time by using the DFT B3LYP and QCISD methods. The geometries of the stationary points on the potential energy surfaces of the reactions were optimized at the B3LYP/6-311+G (d,p) level of theory. The calculated results indicated that the mechanisms of the insertion reactions of H2GeLiF with HCl , H2S , and PH3are identical to each other. The QCISD/6-311++G(d,p)//B3LYP/6-311+G(d,p) calculated potential energy barriers of the three reactions are 81.80, 123.39 and 205.56 kJ/mol, and the reacti
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Kakiuchi, Fumitoshi, Naoki Kimura, Shiori Katta, Yoichi Kitazawa, and Takuya Kochi. "Deuterium-Labeling Studies on the C–H/Olefin Coupling of Aromatic Ketones Catalyzed by Fe(PMe3)4." Synthesis 53, no. 18 (2021): 3383–89. http://dx.doi.org/10.1055/s-0040-1706040.

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AbstractDeuterium-labeling experiments were performed for the Fe(PMe3)4-catalyzed C–H/olefin coupling using a deuterium-labeled aromatic ketone with various alkenes. While the reactions with a variety of alkenes provided the linear alkylation products formed via 1,2-insertion of alkene into an Fe–H bond, the reversible 2,1-insertion proceeded during the reaction highly depends on the choice of the alkene. No H/D scrambling resulting from 2,1-insertion/β-elimination was detected for the reactions with a vinylsilane and N-vinylcarbazole, but the reactions­ with styrenes are considered to involve
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Wiberg, N., G. Preiner, G. Wagner, and H. Köpf. "Reaktivität des labilen, durch Adduktbildung mit Ph2C=NSiMe3 gespeicherten Silaethens Me2Si=C(SiMe3)2 / Reactivity of the Labile Silaethene Me2Si = C(SiMe3)2, Stored as Ph2C =NSiMe3 Adducts." Zeitschrift für Naturforschung B 42, no. 9 (1987): 1062–74. http://dx.doi.org/10.1515/znb-1987-0902.

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Silaethene Me2Si = C(SiMe3)2 (1), stored as Ph2C=NSiMe3 adducts and regenerated from the adducts at about 100 °C as a reaction intermediate, combines with reactants a-b (e. g. HO-H, RO-H. RCOO-H, RS-H. RHN-H, Ph2CN-H, RO-SiR3, R2N-SiR3, Ph2CN-SiR3, Cl-GeR3, Cl-SnR3) with insertion into the a-b bond, with a=b (e.g. 0 = CPh2, Me3SiN = CPh2, CH2=CHOMe, cis-piperylene), a=b=c (e.g. RN = N = N, O = N=N). a=b-c=d (e.g. butadiene, isoprene, trans-piperylene, 2,3-dimethylbutadiene, cyclopentadiene, anthracene, benzophenone, N-trimethylsilylbenzophenoneimine) under [2+2]-, [2+3]- as well as [2+A]-cyclo
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Khade, Rahul, Xinyi Zhao, Carolyn Wang, and Yong Zhang. "Biocatalytic Carbenoid N-H Insertions Via Engineered Myoglobins: A Systematic Reaction Mechanism Study." ECS Meeting Abstracts MA2024-01, no. 14 (2024): 1114. http://dx.doi.org/10.1149/ma2024-01141114mtgabs.

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Recently engineered myoglobins have demonstrated excellent biocatalytic activities for a broad range of carbenoid N-H insertion reactions with up to >99% yield. Such biocatalysts offer various tuning points beyond protein residues, such as metal center, and axial ligand, to regulate different chemical reactivities. However, there is no computational mechanistic study to reveal its basic reaction mechanism, which could be utilized to study effects of different catalyst component for rational biocatalyst design. The reported computational mechanistic papers of other heme protein catalyzed N-H
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Zhang, Xiaomei, Ming Ma, and Jianbo Wang. "Catalytic asymmetric S-H insertion reaction of carbenoids." Arkivoc 2003, no. 2 (2003): 84–91. http://dx.doi.org/10.3998/ark.5550190.0004.210.

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Li, Mao-Lin, Jin-Han Yu, Yi-Hao Li, Shou-Fei Zhu, and Qi-Lin Zhou. "Highly enantioselective carbene insertion into N–H bonds of aliphatic amines." Science 366, no. 6468 (2019): 990–94. http://dx.doi.org/10.1126/science.aaw9939.

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Aliphatic amines strongly coordinate, and therefore easily inhibit, the activity of transition-metal catalysts, posing a marked challenge to nitrogen-hydrogen (N–H) insertion reactions. Here, we report highly enantioselective carbene insertion into N–H bonds of aliphatic amines using two catalysts in tandem: an achiral copper complex and chiral amino-thiourea. Coordination by a homoscorpionate ligand protects the copper center that activates the carbene precursor. The chiral amino-thiourea catalyst then promotes enantioselective proton transfer to generate the stereocenter of the insertion pro
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Cai, Yan, Haihong Ge, Weize Sun, and Zhiwei Miao. "Trifluoroborane-Catalyzed C–H Functionalization/S–H Insertion Reaction: Construction of N,S-Acetal Quaternary Centers." Synthesis 47, no. 11 (2015): 1669–77. http://dx.doi.org/10.1055/s-0034-1380384.

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The trifluoroborane-catalyzed C–H functionalization/S–H insertion reaction of α-diazophosphonates with thiols has been developed. A plausible reaction mechanism has been proposed to understand the combined reaction. This process provides straightforward access to N,S-acetals containing quaternary centers in moderate to good yields and chemoselectivity.
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Zhang, Ming-Xia, Ming-Jun Zhang, Wen-Zuo Li, Qing-Zhong Li, and Jian-Bo Cheng. "Structure ofH2GeFMgFand its insertion reactions withRH(R=F,OH,NH2)." Journal of Theoretical and Computational Chemistry 14, no. 01 (2015): 1550004. http://dx.doi.org/10.1142/s0219633615500042.

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The structures of the germylenoid H2GeFMgF and its insertion reactions with RH ( R = F , OH , NH2) were studied using the DFT B3LYP and QCISD approaches for the first time. The geometries of all of the stationary points were optimized at the B3LYP/6-311+G (d, p) level of theory. And then the QCISD/6-311++G (d, p) single-point energies were calculated. The solvent effects on the geometries and insertion reactions were also computed using the PCM model. The calculated results suggested that H2GeFMgF had three equilibrium configurations, in which the p-complex structure had the lowest energy and
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Chen, Lianfen, Chaoyi Zhao, Weixian Mo, Chunsheng Li, and Xiaoming Lin. "X-H Bond Insertion Promoted by Heterogeneous Dirhodium Metal–Organic Cage with Alkynes as Safe Carbene Precursors." Molecules 28, no. 2 (2023): 608. http://dx.doi.org/10.3390/molecules28020608.

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A facile and efficient methodology for the generation of the C-X (X = Si, B) bond through a carbene insertion process was demonstrated using a dirhodium metal–organic cage, MOC-Rh-1, as a heterogeneous catalyst. A series of functionalized alkynes were utilized as safe carbene precursors to furnish Si-H and B-H insertion products in moderate to excellent yields. These reactions featured a high atom-economy, a broad substrate scope, and mild reaction conditions. Moreover, the as-prepared MOC-Rh-1 catalyst was recovered easily from the reaction system by simple centrifugation and reused for ten r
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Dissertations / Theses on the topic "H‐insertion reaction"

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Burtoloso, Antonio Carlos Bender. "3-azetidinonas e 3-azetidinois : preparação e aplicações na sintese de azetidinas substituidas." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249762.

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Orientador: Carlos Roque Duarte Correia<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Quimica<br>Made available in DSpace on 2018-08-05T22:30:16Z (GMT). No. of bitstreams: 1 Burtoloso_AntonioCarlosBender_D.pdf: 10110814 bytes, checksum: 1e36973f12232933308e658cdad952fe (MD5) Previous issue date: 2006<br>Doutorado<br>Quimica Organica<br>Doutor em Ciências
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Kawamura, Meire Yasuko. "Emprego de diazocetonas α,β-insaturadas com geometria Z na direta construção de esqueletos indolizidínicos e piperidínicos funcionalizados." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/75/75133/tde-26082016-104019/.

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Pumiliotoxinas e seus congêneres são compostos isolados da pele de algumas espécies de sapos das famílias Dendrobatidae, Mantellidae, Bufonidae, e Myobatrachidae, apresentando interessantes propriedades farmacológicas. As pumiliotoxinas, embora tóxicas, apresentam consideráveis atividades cardiotônicas, assim, acredita-se que as homopumiliotoxinas, as desmetilpumiliotoxinas e as desidrodesmetilpumiliotoxinas também devam apresentar. Nesse sentido, a síntese destes compostos é de extrema valia para a comunidade científica. As diazocetonas &alpha;,&beta;-insaturadas são intermediários promissore
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Bailey, Christopher David. "New Pd(II) Catalysed C-H Insertion Reactions of Aryl Ureas." Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520217.

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Erhunmwunse, Orobosa Marvis. "Template directed C-H insertion reactions for stereocontrolled synthesis of heterocycles." Thesis, Durham University, 2009. http://etheses.dur.ac.uk/259/.

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Template Directed C-H Insertion Reactions for Stereocontrolled Synthesis of Heterocycles Orobosa Marvis Erhunmwunse, PhD. Non aromatic heterocycles and their analogues are abundant in a large variety of bioactive natural products and continue to play crucial roles in modern day chemotherapy. The bioactivities of these heterocycles are highly dependent on the stereochemistry of the substituents and therefore the development of elegant new methodologies for the selective construction of heterocycles remains attractive to the synthetic chemist. Described in this thesis, is a tandem methodology fo
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Annapureddy, Raja Sekarreddy. "Ruthenium porphyrin catalyzed carbene mediated C-H insertion and cycloaddition reactions." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/206316.

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Pintori, Didier Gil. "Novel benzyne insertion reactions & medium-ring synthesis by oxidative C-H coupling." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5669.

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This thesis is divided into two main chapters, which are focused on two separated and uncorrelated research areas. The first part of this thesis is dedicated to the research I carried out in benzyne chemistry and the second part is focused on catalytic C-H bond activation. In the first place, a novel insertion reaction of arynes into the nitrogen-carbonyl σ-bond of amides has been investigated as a rapid and powerful approach for the preparation of valuable ortho-disubstituted arenes. Readily available aromatic amides undergo smooth insertion when treated with O-triflatophenyl silane aryne pre
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Grand, Simon Christopher. "The synthesis of carbocyclic nucleoside analogues using rhodium carbenoid C-H insertion reactions." Thesis, University of Nottingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367403.

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Mariani, Francesco. "New Palladium-Catalysed Intramolecular Coupling Reactions: Nucleophilic Addition toAldehydes and C-H Carbene Insertion." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/398849.

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Although sygma-aryl and sygma-vinylpalladium(II) complexes are commonly used as electrophiles in C—C bond forming reactions, recent research has demonstrated that the same palladium intermediates can also react with carbon-heteroatom multiple bonds in a nucleophilic manner. Continuing with the interest of our group on the palladium-catalysed intramolecular coupling of aryl halides whit carbonyl compounds, we have expanded our previous findings to substrates containing other carbon-heteroatom multiple bonds. In this context, the first objective of the PhD Thesis has been the study of the dua
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Cleary, Sarah Elizabeth. "Fragmentation, Rearrangement, And C-H Insertion: Reactions Of Vinyl Cations Derived From Diazo Carbonyls." ScholarWorks @ UVM, 2018. https://scholarworks.uvm.edu/graddis/925.

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Many commercialized medicinal compounds are analogs of chemicals isolated from sources found in nature (also called natural products). However, the natural sources of these chemicals, such as plants, fungi, or insects, only offer small quantities of these bioactive agents. Thus, it is typically desirable to find ways to synthesize these products and their analogs in large quantities using cost-effective methods that also minimize the impact on the environment. It is also important to develop strategies that expedite the process of modifying the natural products, which allows medicinal chemists
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Lee, Elaine C. "Improved synthesis and application of planar-chiral nucleophilic catalysts in asymmetric reactions and copper-catalyzed enantioselective N-H insertion reactions." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/39741.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2007.<br>Vita.<br>Includes bibliographical references.<br>The development of an improved synthesis of nucleophilic planar-chiral catalysts is described in Chapter 1. This route is amenable to scale-up and preparative chiral HPLC is unnecessary to resolve the racemic catalysts. Using planar-chiral catalysts, two synthetic methodology projects have been developed: Chapter 2 describes the first asymmetric synthesis of trans P-lactams, and Chapter 3 describes the asymmetric synthesis of tertiary a-chloroesters. In the chap
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Book chapters on the topic "H‐insertion reaction"

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Zhao, Da. "Synthesis of Carborane-Functionalized Heterocycles: Dearomative [2 + 2] Cycloaddition and sp2 C–H Insertion Reaction." In Functionalization of Carborane via Carboryne Intermediates. Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-1569-4_3.

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Taber, Douglass F., and Pramod V. Joshi. "Cyclopentane Construction by Rhodium(II)-Mediated Intramolecular C-H Insertion." In Modern Rhodium-Catalyzed Organic Reactions. Wiley-VCH Verlag GmbH & Co. KGaA, 2005. http://dx.doi.org/10.1002/3527604693.ch16.

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Ward, Thomas R., and Michela M. Pellizzoni. "Hybrid Catalysts for CH Activation and Other XH Insertion Reactions." In Artificial Metalloenzymes and MetalloDNAzymes in Catalysis. Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527804085.ch9.

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Rosi, Marzio, Leonardo Pacifici, Dimitrios Skouteris, et al. "A Computational Study on the Insertion of N(2D) into a C—H or C—C Bond: The Reactions of N(2D) with Benzene and Toluene and Their Implications on the Chemistry of Titan." In Computational Science and Its Applications – ICCSA 2020. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-58808-3_54.

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Taber, Douglass F. "Natural Product Synthesis by C–H Functionalization: (±)-Allokainic Acid (Wee), (–)-Cameroonan-7α-ol (Taber), (+)-Lithospermic Acid (Yu), (–)-Manabacanine (Kroutil), Streptorubin B, and Metacycloprodigiosin (Challis)." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0022.

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Andrew G.H. Wee of the University of Regina showed (Org. Lett. 2010, 12, 5386) that with the bulky BTMSM group on N and the electron-withdrawing pivaloyloxy group deactivating the alternative C–H insertion site, the diazo ketone 1 cleanly cyclized to 2, with 21:1 diastereocontrol. Oxidative cleavage of the arene followed by amide reduction and methylenation of the ketone converted 2 into (±)-allokainic acid 3. Intermolecular C–H insertion was the key step in a complementary route to (±)-kainic acid reported (Org. Lett. 2011, 13, 2674) by Takehiko Yoshimitsu of Osaka University. Rh-mediated int
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Stephenson, G. R., M. Perseghini, and A. Togni. "C—H Insertion Reactions." In Compounds with Transition Metal-Carbon pi-Bonds and Compounds of Groups 10-8 (Ni, Pd, Pt, Co, Rh, Ir, Fe, Ru, Os). Georg Thieme Verlag KG, 2001. http://dx.doi.org/10.1055/sos-sd-001-00825.

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"Catalytic C-H Insertion Reactions." In Active Pharmaceutical Ingredients in Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527807253.ch10.

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Wang, P. S., M. Sayed, and L. Z. Gong. "47.1.2.5 Allylic C—H Functionalization." In Knowledge Updates 2023/1. Georg Thieme Verlag KG, 2023. http://dx.doi.org/10.1055/sos-sd-147-00159.

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AbstractThe direct functionalization of allylic C(sp3)—H bonds allows alkenes to serve as versatile allylating agents capable of undergoing diverse bond-forming reactions, thereby enabling rapid access to alkene-bearing structural complexity from readily accessible feedstocks. In this review, representative reports on allylic C—H functionalization reactions published since 2013 are summarized by describing six types of allylic C—H activation modes: C—H insertion, hydrogen-atom transfer, concerted metalation/deprotonation (CMD), concerted proton and two-electron transfer (CPTET), base-mediated
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Heydt, H. "Insertion Reactions into Various X—H Bonds." In Heteroatom Analogues of Aldehydes and Ketones. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-027-00796.

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Taber, Douglass F., Michael J. Hennessy, R. Scott Hoerrne, Krishna Raman, Robert E. Ruckle, and Jonathan S. Schuchardt. "Cyclopentane Construction by Rh-Catalyzed Intramolecular C-H Insertion." In Catalysis of Organic Reactions. CRC Press, 2020. http://dx.doi.org/10.1201/9781003066446-5.

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Conference papers on the topic "H‐insertion reaction"

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Cancio, María José, Juan R. Collet-Lacoste, and Teresa E. Perez. "Environmental and Metallurgical Parameters Affecting Sulfide Stress Cracking Resistance of High Strength Steels." In CORROSION 2010. NACE International, 2010. https://doi.org/10.5006/c2010-10283.

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Abstract Crack propagation in the presence of sour gas is the conjunction of electrochemical reactions and metallurgical processes that increase hydrogen absorption at the crack tip and therefore produces embrittlement. To evaluate Oil Country Tubular Goods (OCTG) susceptibility to Sulfide Stress Cracking (SSC) in wet H2S environments NACE International adopted different testing methods. Particularly, Method D is used for design/fitness-for-service, material qualification and specification purposes. The material resistance to crack propagation in an aggressive environment is expressed in terms
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Lian, T., S. E. Bromberg, H. Yang, M. Asplund, R. G. Bergman, and C. B. Harris. "Femtosecond IR Studies of Alkane C-H Bond Activation by Organometallic Compounds." In International Conference on Ultrafast Phenomena. Optica Publishing Group, 1996. http://dx.doi.org/10.1364/up.1996.fe.27a.

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The mechanism of alkane C-H bond activation by transition metal complexes such as CpM(CO)2 (M=Rh, Ir) has been intensely studied because it represents a first step in a catalytic process using unreactive hydrocarbons.[1] The bond activation reaction starts with the formation of monocarbonyl intermediates such as CpRh(CO). These species have been detected in the gas phase[2] and in liquefied rare Kr and Xe[3] by µs time resolved IR spectroscopy. Unfortunately, the subsequent oxidative insertion of CpRh(CO) into the C-H bond is not well understood due to its rapid rate and low quantum yield (~1%
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Patel, Sanket B., Sunil V. Dingare, and Sandeep S. Kore. "Experimental and Computational Analysis of Heat Transfer Performance of Different Ribs Shapes in Forced Convection." In ASME 2017 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/imece2017-72721.

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In applications such as gas turbine blades, electronic cooling devices, heat exchangers and gas-cooled nuclear reactor fuel pins high inlet temperatures has n major impact on components. Insertion of increases the production of turbulent kinetic energy, which improves turbulent heat transfer in the channel. Hence evaluating different shapes will help finding optimum geometry for enhancement in heat transfer. Based on the numerical analysis done by [10]Mi-Ae Moon, Min-Jung Park and Kwang-Yong Kim, the heat transfer and friction loss performances of rib roughened rectangular cooling channels hav
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Dejana, E., L. R. Languino, S. Colella, E. Plow, M. Ginsberg, and P. C. Marchisio. "THE LOCALIZATION OF PLATELET GpIIb-IIIa RELATED PROTEINS IN ENDOTHELIAL CELL ADHESION STRUCTURE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642814.

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Different laboratories bave reported that human endothelial cells (EC) synthesize and express surface proteins biochemically and immunologically related to platelet GpIIb-IIIa. However the functional role of this glycoprotein complex in EC has not yet been elucidated. In this study we investigated whether these molecules are involved in the process of EC adhesion to different substrata. Cultured human umbilical vein ECs ,seeded on purified fibrinogen(fg), or vitronectin(VN) coated coverslips, adhered ,underwent spreading, organization of thick microfilament bundles and formation of focal conta
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Di Piazza, I., M. Tarantino, P. Agostini, and P. Gaggini. "HELENA: A Heavy Liquid Metal Multi-Purpose Loop for Thermal-Hydraulics, Corrosion and Component Test." In 2014 22nd International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/icone22-30784.

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Since the Lead-cooled Fast Reactor (LFR) has been conceptualized in the frame of GEN IV International Forum (GIF), ENEA is strongly involved on the HLM technology development. Currently ENEA has implemented large competencies and capabilities in the field of HLM thermal-hydraulic, coolant technology, material for high temperature applications, corrosion and material protection. In this frame, the HELENA facility is well instrumented and it represents a loop working in pure lead for experiments in the field of corrosion for LFR structural materials, component test, and thermal-hydraulic investi
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Reports on the topic "H‐insertion reaction"

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Klobukowski, Erik. Bulk gold catalyzed oxidation reactions of amines and isocyanides and iron porphyrin catalyzed N-H and O-H bond insertion/cyclization reactions of diamines and aminoalcohols. Office of Scientific and Technical Information (OSTI), 2011. http://dx.doi.org/10.2172/1048517.

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