Relevant bibliographies by topics / H2-receptor antagonist (H2RA)

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Academic literature on the topic 'H2-receptor antagonist (H2RA)'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "H2-receptor antagonist (H2RA)"

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Saroh, Muya, Agung Endro Nugroho, and I. Dewa Putu Pramantara. "Efektivitas H2-Receptor Antagonist dan Proton Pump Inhibitor sebagai Profilaksis Stress Ulcer pada Pasien dengan Ventilator Mekanik." Majalah Farmaseutik 20, no. 2 (2024): 211. http://dx.doi.org/10.22146/farmaseutik.v20i2.88994.

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Pasien kritis lebih berisiko mengalami stress ulcer yang dikarenakan oleh perubahan perfusi mukosa lambung, penurunan faktor pelindung mukosa dan peningkatan asam lambung, sehingga menyebabkan risiko perdarahan saluran pencernaan bagian atas. Pemberian profilaksis stress ulcer direkomendasikan pada pasien yang memiliki faktor risiko terjadinya perdarahan stress ulcer, terutama pasien dengan penggunaan ventilator mekanis. Penelitian ini bertujuan untuk mengetahui perbandingan efikasi PPI dan H2RA sebagai profilaksis stress ulcer pada pasien dengan penggunaan ventilator mekanis.Pada studi kohort
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Vashistha, Nitin, Dinesh Singhal, Gurpreet Makkar, Suneel Chakravarty, and Vivek Raj. "Management of Giant Gastric Ulcer Perforation: Report of a Case and Review of the Literature." Case Reports in Surgery 2016 (2016): 1–3. http://dx.doi.org/10.1155/2016/4681989.

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Giant gastric ulcer (GGU) is defined as an ulcer more than 3 cm in diameter. Now infrequent in clinical practice, in the pre-H2 receptor antagonist (H2RA) era, the incidence of GGU varied between 12 and 24% of all gastric ulcers. Proton pump inhibitors reportedly achieve better healing rates and symptom relief in comparison to H2RA. The GGU is associated with high incidence of serious complications such as hemorrhage. A perforated GGU though rare (<2%) offers serious challenges in management. We report one such case wherein the role of multidetector CT scan (MDCT) for diagnosis and treatmen
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Macaione, Francesca, Carla Montaina, Salvatore Evola, Giuseppina Novo, and Salvatore Novo. "Impact of Dual Antiplatelet Therapy with Proton Pump Inhibitors on the Outcome of Patients with Acute Coronary Syndrome Undergoing Drug-Eluting Stent Implantation." ISRN Cardiology 2012 (June 27, 2012): 1–8. http://dx.doi.org/10.5402/2012/692761.

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This study aimed to assess if proton pump inhibitors (PPIs) may reduce the effectiveness of clopidogrel, than H2 antagonist (anti-H2) in order to determine rehospitalization for acute coronary syndrome (re-ACS), target vessel revascularization (TVR) and cardiac death. This case-control study included 176 patients with ACS undergoing angioplasty (PCI) with drug-eluting stent implantation. The population was divided into two groups: PPI group (n=121) consisting of patients receiving at discharge dual antiplatelet therapy (DAT) plus PPI and anti-H2 group (n=55), consisting of patients receiving a
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Jiang, Mengyuan, Pan Chen, and Qiang Gao. "Systematic Review and Net-Work Meta-Analysis of Upper Gastrointestinal Hemorrhage Interventions." Cellular Physiology and Biochemistry 39, no. 6 (2016): 2477–91. http://dx.doi.org/10.1159/000452515.

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Background/Aims: Upper gastrointestinal hemorrhage (UGH) is a serious medical condition which affects a large number of individuals. Endoscopic therapy accompanied by medication is a standard approach that is used to improve the prognosis of UGH patients and a few medications have been developed including proton pump inhibitors (PPIs), histamine H2 receptor antagonist (H2RA), somatostatin analogues and tranexamic acid. This study is set to compare the efficacy and safety of various medical interventions that are used to manage upper gastrointestinal bleeding. Methods: We searched PubMed, Cochr
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Lin, Tsung-Kun, Chin-Feng Tsai, Jing-Yang Huang, Lung-Fa Pan, and Gwo-Ping Jong. "Exposure to Proton Pump Inhibitors and the Risk of Incident Asthma in Patients with Coronary Artery Diseases: A Population-Based Cohort Study." Journal of Personalized Medicine 12, no. 5 (2022): 824. http://dx.doi.org/10.3390/jpm12050824.

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We aimed to determine the association between proton pump inhibitor (PPI) use and incident asthma in patients with coronary artery disease (CAD). This nationwide cohort study collected claims data from the Taiwanese Bureau of National Health Insurance from 2004 to 2013. The primary outcome, i.e., the risk of incident asthma, was assessed by estimating hazard ratios (HRs) and 95% confidence intervals (CIs). The adjusted HR of asthma development was estimated using the Cox regression model. Sensitivity and subgroup analyses were also conducted. A total of 8894 PPI users and 12,684 H2-receptor an
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Abdul-Hussein, Mustafa, Janice Freeman, and Donald O. Castell. "Mo1149 Concomitant Administration of H2 Receptor Antagonist (H2RA) and Proton Pump Inhibitor (PPI). Reasonable or Ridiculous?" Gastroenterology 148, no. 4 (2015): S—621. http://dx.doi.org/10.1016/s0016-5085(15)32094-1.

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Mosholder, Andrew D., Hector S. Izurieta, Rongmei Zhang, et al. "Use of proton pump inhibitors and risk of severe COVID‐19: A case–control study in United States Medicare beneficiaries." Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 44, no. 10 (2024): 803–10. http://dx.doi.org/10.1002/phar.4614.

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AbstractBackgroundConcerns have been raised regarding proton pump inhibitor (PPI) use and risk of severe coronavirus disease 2019 (COVID‐19). Observational studies have yielded heterogeneous results and were subject to important methodological limitations.AimsTo examine the association between the receipt of PPIs and risk of COVID‐19 hospitalizations and severe in‐hospital outcomes or death.MethodsCase–control study among Medicare fee‐for‐service beneficiaries 66+ years old with gastroesophageal reflux disorder (GERD). Within this population, we identified cases by an incident hospital dischar
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Yamamichi, Nobutake, Takeshi Shimamoto, Yu Takahashi, et al. "Trends in proton pump inhibitor use, reflux esophagitis, and various upper gastrointestinal symptoms from 2010 to 2019 in Japan." PLOS ONE 17, no. 6 (2022): e0270252. http://dx.doi.org/10.1371/journal.pone.0270252.

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The increasing usage of proton pump inhibitors (PPIs) has been reported worldwide, but information on PPI use in East Asia is inadequate. This study aimed to examine the trends in PPI use in Japan, along with the changes in histamine H2 receptor antagonist (H2RA) use, disease rate of reflux esophagitis, and the prevalence of upper gastrointestinal symptoms. We analyzed 217,712 healthy subjects (127,607 men and 90,105 women; 51.4 ± 9.7 years old) participating in the health check program from 2010 to 2019. Various upper gastrointestinal symptoms were evaluated using the frequency scale for the
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FUKUDA, T., S. SAKURAI, and M. KUDO. "A STUDY ON THE RELATIONSHIP BETWEEN HELICOBACTER PYLORI AND TRACE ELEMENTS IN GASTRIC MUCOSA." International Journal of PIXE 16, no. 01n02 (2006): 55–68. http://dx.doi.org/10.1142/s0129083506000812.

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H2 receptor antagonist (H2RA) and proton pump inhibitor(PPI) are often used to treat gastric ulcers, in addition to the zinc-L-carcino-complex which is commonly adopted for such therapies. However, there have been no previous reports detailing the levels and distribution of zinc in human gastric mucosa. The aim of our current study is to clarify the relationship between Helicobacter pylori infection and trace elements such as zinc in gastric mucosa using particle induced X-ray emission (PIXE). Forty gastric ulcer patients were chosen as subjects of this study and divided into two groups. One i
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Park, Hyun Jin, Minoh Ko, In-Wha Kim, and Jung Mi Oh. "Personalized Risk Assessment for Taxane-Induced Hypersensitivity Reactions: A Systematic Review and Meta-Analysis." Journal of Personalized Medicine 15, no. 1 (2024): 2. https://doi.org/10.3390/jpm15010002.

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Background/Objectives: Taxanes, including paclitaxel and docetaxel, are widely used in cancer treatment but frequently cause hypersensitivity reactions (HSRs), disrupting treatment continuity. This meta-analysis aimed to identify consistent risk factors for taxane-induced HSRs to support personalized risk assessments and optimize therapeutic outcomes. Methods: This systematic review and meta-analysis followed the PRISMA guidelines and was registered with PROSPERO (CRD42023476738). Comprehensive literature searches were conducted up to 30 June 2024. The quality of the studies was assessed using
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Book chapters on the topic "H2-receptor antagonist (H2RA)"

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Faruk Khan, M. O. "Antihistamines, Proton Pump Inhibitors and Related Drugs." In Medicinal Chemistry for Pharmacy Students. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815179729124030008.

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This chapter is a comprehensive account of the medicinal chemistry of antihistamines, H2 receptor (H2R) blockers, H3 receptor (H3R) blockers, and proton pump inhibitors (PPIs). It provides the mechanism of drug action and detailed structure-activity relationship (SAR) of the drugs in these classes to give the knowledge base for pharmacists. After studying this chapter, students will be able to: Describe the physiochemical properties of histamine and histamine receptors. • Identify chemical classifications and describe the SAR of antihistamines, H2R and H3R antagonists. • Differentiate receptor
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Wallmark, Bjorn, David Keeling, and Per Lindberg. "Inhibitors of Gastric H +, K+ -ATPase." In Pre-Equilibrium Nuclear Reactions. Oxford University PressOxford, 1992. http://dx.doi.org/10.1093/oso/9780198517344.003.0014.

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Abstract Acid-related diseases include reflux oesophagitis, duodenal ulcer, gastric ulcer, and the Zollinger-Ellison syndrome. These disorders are treated by a reduction of gastric acid secretion which can be achieved by surgery, antacids, or pharmacological agents. Several classes of antisecretory agent have been developed and introduced into clinical use. These include anti cholinergic compounds, such as pirenzipine, and the histamine H2-receptor antagonists (H2RAs), such as cimetidine (Black et al. 1972). The intro duction of cimetidine was followed later by other H2RAs, such as ranitidine
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Garg, Dr Gopal. "Antiulcer Agents." In Edited Book of Pharmacology-III [According to Latest Syllabus of B. Pharm-VI Semester of Pharmacy Council of India]. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/nbennurphch2.

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Antiulcer agents are essential medications used to manage and treat conditions like peptic ulcers, gastroesophageal reflux disease (GERD), and other acid-related disorders of the gastrointestinal tract. These agents are classified into several categories based on their mechanisms of action: proton pump inhibitors (PPIs), H2-receptor antagonists (H2RAs), antacids, mucosal protective agents, antibiotics, and prostaglandin analogues. PPIs, such as omeprazole and lansoprazole, work by irreversibly inhibiting the hydrogen-potassium ATPase enzyme, significantly reducing gastric acid secretion. H2RAs
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