Academic literature on the topic 'HaCaT Cells Lines'

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Journal articles on the topic "HaCaT Cells Lines"

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Karatay, Kadriye Busra, Fazilet Zumrut Biber Muftuler, Benedict Law, and Omer Aras. "Methanolic extract of Kigelia africana and wound healing: an in vitro study." Journal of Wound Care 32, no. 6 (2023): 392–98. http://dx.doi.org/10.12968/jowc.2023.32.6.392.

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Objective: Kigelia africana (Lam.) Benth. (Bignoniaceae) syn. Kigelia pinnata (Jacq. DC) is a tropical plant that is native to tropical Africa. The aim of this study was to determine if a methanolic extract prepared from Kigelia africana (KAE) can promote wound healing in treated human normal epidermal keratinocyte (HaCaT) cells and human normal foreskin fibroblast cell line (BJ) cells compared with untreated cells. Method: Experimental steps included: the methanolic extraction of the leaf and fruit of the Kigelia africana plant; the preparation of HaCaT and BJ cell lines; cell culture with a
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Mantso, Theodora, Dimitrios Trafalis, Sotiris Botaitis, et al. "Novel Docosahexaenoic Acid Ester of Phloridzin Inhibits Proliferation and Triggers Apoptosis in an In Vitro Model of Skin Cancer." Antioxidants 7, no. 12 (2018): 188. http://dx.doi.org/10.3390/antiox7120188.

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Skin cancer is among the most common cancer types accompanied by rapidly increasing incidence rates, thus making the development of more efficient therapeutic approaches a necessity. Recent studies have revealed the potential role of decosahexaenoic acid ester of phloridzin (PZDHA) in suppressing proliferation of liver, breast, and blood cancer cell lines. In the present study, we investigated the cytotoxic potential of PZDHA in an in vitro model of skin cancer consisting of melanoma (A375), epidermoid carcinoma (A431), and non-tumorigenic (HaCaT) cell lines. Decosahexaenoic acid ester of phlo
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Vildanova, Mariya, Polina Vishnyakova, Aleena Saidova, Victoria Konduktorova, Galina Onishchenko, and Elena Smirnova. "Gibberellic Acid Initiates ER Stress and Activation of Differentiation in Cultured Human Immortalized Keratinocytes HaCaT and Epidermoid Carcinoma Cells A431." Pharmaceutics 13, no. 11 (2021): 1813. http://dx.doi.org/10.3390/pharmaceutics13111813.

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Diterpenoid plant hormone gibberellic acid (GA) plays an important role in regulation of plant growth and development and is commonly used in agriculture for activation of plant growth and food production. It is known that many plant-derived compounds have miscellaneous biological effects on animals and humans, influencing specific cellular functions and metabolic pathways. However, the effect of GA on animal and human cells remains controversial. We investigated the effect of GA on cultured human cell lines of epidermoid origin—immortalized non-tumorigenic keratinocytes HaCaT and carcinoma A4
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Elliyanti, Aisyah, Andani Eka Putra, Yunia Sribudiani, et al. "Epidermal Growth Factor and Adenosine Triphosphate Induce Natrium Iodide Symporter Expression in Breast Cancer Cell Lines." Open Access Macedonian Journal of Medical Sciences 7, no. 13 (2019): 2088–92. http://dx.doi.org/10.3889/oamjms.2019.620.

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AIM: This study aims to investigate the effect of ATP, EGF and combination of those two to the Natrium Iodide Symporter (NIS) expression in MCF7, SKBR3 and HaCaT cell lines.
 METHODS: MCF7, SKBR3 and HaCaT cell lines were treated with ATP, EGF and combination of those two for 6, 12 and 24 hours. The expression of NIS mRNA was measured through quantitative-reverse transcription-polymerase chain reaction (qRT-PCR). The NIS protein expression was confirmed by immunocytofluorescence.
 RESULTS: NIS mRNA was expressed in SKBR3 and HaCaT cell lines but not in MCF7. The levels of NIS mRNA ex
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Traver-Méndez, Valeria, Octavi Camps-Font, Francesc Ventura, et al. "In Vitro Characterization of an Anodized Surface of a Dental Implant Collar and Dental Abutment on Peri-Implant Cellular Response." Materials 16, no. 17 (2023): 6012. http://dx.doi.org/10.3390/ma16176012.

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The purpose of this paper was to determine the effect of anodization on the in vitro proliferation and adhesion of immortalized human keratinocytes (HaCats) and mouse bone marrow-derived mesenchymal stem cells (BM-MSCs) in Titanium Grade 23 (Ti6Al4V ELI) discs and to describe the surface topography, roughness, and composition of dental implants (body and collar) and abutments submitted to an area-specific anodization process. HaCat cells and BM-MSCs were seeded onto discs with three different surface treatments: machined, area-specific anodization for abutments, and area-specific anodization f
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Boukamp, P., R. T. Petrussevska, D. Breitkreutz, J. Hornung, A. Markham, and N. E. Fusenig. "Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line." Journal of Cell Biology 106, no. 3 (1988): 761–71. http://dx.doi.org/10.1083/jcb.106.3.761.

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In contrast to mouse epidermal cells, human skin keratinocytes are rather resistant to transformation in vitro. Immortalization has been achieved by SV40 but has resulted in cell lines with altered differentiation. We have established a spontaneously transformed human epithelial cell line from adult skin, which maintains full epidermal differentiation capacity. This HaCaT cell line is obviously immortal (greater than 140 passages), has a transformed phenotype in vitro (clonogenic on plastic and in agar) but remains nontumorigenic. Despite the altered and unlimited growth potential, HaCaT cells
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Schadich, Ermin, Jan Hlaváč, Tereza Volná, Lakshman Varanasi, Marián Hajdúch, and Petr Džubák. "Effects of Ginger Phenylpropanoids and Quercetin on Nrf2-ARE Pathway in Human BJ Fibroblasts and HaCaT Keratinocytes." BioMed Research International 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/2173275.

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Quercetin and phenylpropanoids are well known chemoprotective compounds identified in many plants. This study was aimed at determining their effects on activation of Nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant response element (Nrf2-ARE) signalling pathway and expression of its important downstream effector phase II detoxification enzyme glutathione-S-transferase P1 (GSTP1) in BJ foreskin fibroblasts and skin HaCaT keratinocytes. Cell lines and their corresponding Nrf2-ARE luciferase reporter cells were treated by ginger phenylpropanoids and quercetin for 10 h and the level
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Husain, Noreen. "Sulphide Donor Exhibits Cytoprotective and Antioxidative Activity in UV-induced HaCaT Cell Lines." ASM Science Journal 17 (December 21, 2022): 1–6. http://dx.doi.org/10.32802/asmscj.2022.1242.

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Oxidative stress due to excessive of reactive oxygen species (ROS) in the body is commonly associated as one of the underlying mechanisms of ultraviolet radiation (UV)-induced damage in the skin. Reactive sulphur species (RSS) has been implicated with potent antioxidant properties and involves in modulating cellular signalling transduction pathway. In this current study, the potential involvement of the RSS in alleviating UV-induced damage in HaCaT keratinocytes was explored. We first established the suitable dose of UVA and UVB radiation that can depressed HaCaT cells population, 80 mJ/cm2 an
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Perde-Schrepler, Maria, Luminita David, Liliana Olenic, et al. "Gold Nanoparticles Synthesized with a Polyphenols-Rich Extract from Cornelian Cherry (Cornus mas) Fruits: Effects on Human Skin Cells." Journal of Nanomaterials 2016 (2016): 1–13. http://dx.doi.org/10.1155/2016/6986370.

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Gold nanoparticles (GNPs) were obtained by green synthesis with an extract fromCornus masfruits (GNPs-CM), characterized by several methods, and their biologic effects were evaluated on two cell lines: HaCaT, normal keratinocytes, and A431, epidermoid carcinoma. GNPs were spherical with sizes between 2 and 24 nm. Their optical spectra had a dominant plasmonic band centered at 525 nm; zeta potential distribution was narrow, centered at −19.7 mV, and the mean hydrodynamic diameter was 58 nm. GNPs were visualized in both cell types entering the cells by endocytosis. The amount of gold uptaken by
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Gandamalla, Durgaiah, Harikiran Lingabathula, and Narsimha Reddy Yellu. "CYTOTOXICITY EVALUATION OF TITANIUM AND ZINC OXIDE NANOPARTICLES ON HUMAN CELL LINES." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 10 (2017): 240. http://dx.doi.org/10.22159/ijpps.2017v9i11.21924.

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Objective: In vitro cytotoxicity evaluation of titanium dioxide, 20 nm (TNP 20) and zinc oxide, 20 nm (ZNP 20) nanoparticles (NP) were tested on different types of human skin (HaCat), lung (A549), liver (Hep G2) and colon (Caco-2) cell cultures in relevance to human risk assessmentMethods: The different concentrations of test TNP 20 and ZNP 20 1-300 µg/ml were exposed to determine the cell viability reduction on four human cell lines after 48 h post exposure using 3-(4, 5-dimethyl thiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT). The mitochondrial membrane activities of the viable cells we
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Dissertations / Theses on the topic "HaCaT Cells Lines"

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Bretland, Amanda Jane. "Growth, survival and cell death in the epithelial cell lines HaCaT, HT29 and SW742." Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286914.

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Barbosa, João Emanuel Vieira. "Toxic and biochemical impacts of Primextra® Gold TZ and S-metolachlor on human skin and liver cells." Master's thesis, 2021. http://hdl.handle.net/10773/30858.

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With the increase in the human population, came the need to optimize and intensify agricultural production by increasing the use of pesticides and fertilizers. The use of pesticides has been very important in combating pests that, if not stopped, would make it impossible to meet food demand. However, the use of these compounds has harmful consequences. It has been proven that pesticides can have deleterious effects on public and occupational health, by contaminating the drinking water supply, by depositing residues in food, through contamination along the food chain or simply by
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Graham, Stan, Roy Phillip, Myra Zahid, et al. "Ibuprofen Nanoparticles and its cytotoxicity on A549 and HaCaT cell lines." 2016. http://hdl.handle.net/10454/10910.

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yes<br>Ibuprofen (IBF) is an outstanding non-steroidal drug for analgesic and anti-inflammatory therapies but it exhibits poor solubility in water [1, 2]. Increased dosage administration has been linked to gastrointestinal and cardiovascular complications [3]. Many techniques have been employed to improve the solubility of NSAIDs [4]. In this study, the anti-solvent precipitation method was used to make Ibuprofen nanoparticles (IBF NPs). Optimised preparation parameters such as solvent (ethanol), raw drug concentration (400 mg), solvent/anti-solvent ratio (1:50) and surfactant concentrati
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Hong, Ming-Jie, and 洪明杰. "The Effects of Combined Curcumin and Spermine On Human A375 and HaCaT Cell Lines." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/xqfy56.

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碩士<br>高雄醫學大學<br>醫學研究所碩士班<br>106<br>Turmeric has a thousand years of history. Curcumin has many therapeutic effects, including anti-inflammatory, anti-oxidation, anti-cancer, and wound healing. However, one of the major problems with curcumin is perceived to be the low bioavailability. Curcumin can be excluded with human metabolish. Polyamines metabolism is one of the important metabolic pathways in the body. In previous study, it has been that MOdulation of chromatin structure, gene transcription and translation, DNA stabilization, signal transduction, cell growth and proliferation, migration,
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Book chapters on the topic "HaCaT Cells Lines"

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"Investigating the potential effects of 26 GHz 5G microwaves on UV-induced CPD levels in HaCaT keratinocytes in vitro." In Book of Abstracts - RAD 2025 Conference. RAD Centre, Niš, Serbia, 2025. https://doi.org/10.21175/rad.abstr.book.2025.4.10.

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The 5G, the fifth generation of wireless cellular network technology, promises faster speeds, higher data transfer, and lower latency. It is being deployed globally, making it crucial to understand how exposure to 5G networks affects human tissues. In Europe, the 26 GHz frequency band has been approved for 5G telecommunications. While radiofrequency used in 4G networks has been extensively studied, millimeter-wavelength microwaves like those in the 26 GHz range remain less researched. As frequency increases, penetration into human tissue decreases, therefore 26 GHz microwaves mainly absorbed b
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Conference papers on the topic "HaCaT Cells Lines"

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Selvaag, Edgar, Anita B. Petersen, Robert Gniadecki, Tine Thorn, and Hans Christian Wulf. "Antidiabetics and diuretics show phototoxicity in HaCaT cells." In European Conference on Biomedical Optics. Optica Publishing Group, 2001. http://dx.doi.org/10.1364/ecbo.2001.4433_158.

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The antidiabetics tolbutamide, glibenclamide, and glipizide, and the diuretics bendroflumethiazide, butizide, furosemide, hydrochlorothiazide, and trichlormethiazide were investigated for potential phototoxicity in the HaCaT cell line. The cells were incubated with the drugs and then exposed to UVA1 irradiation. The effects of the antioxidants L-ascorbic acid, and α-tocopherol on oxidative DNA damage were assessed. Bendroflumethiazide, furosemide, hydrochlorothiazide, trichlormethiazide, or tolbutamide induced dose-dependent phototoxicity. Cells incubated with bendroflumethiazide, tolbutamide,
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Meister, Joerg, Florian Schelle, Imke Beier, Christoph Bourauel, Matthias Frentzen, and Dominik Kraus. "Influence of USP laser radiation on cell morphology: HaCat and MG-63 cell lines for bone and soft tissue modelling in dentistry." In SPIE BiOS, edited by Peter Rechmann and Daniel Fried. SPIE, 2013. http://dx.doi.org/10.1117/12.2007559.

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Kim, Yejin, Hyemin Kim, Jiwon Choi, et al. "Abstract 4900: The role of Interleukin (IL)-22 on the UVB-induced proliferation and inflammation of human keratinocyte cell line, HaCaT." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4900.

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Sevim, Zeynep, Hulya Dogan, Zeynep Demir, Feride Sena Sezen, and Ramazan Ozgur Dogan. "An Extensive Study: Creation of A New Inverted Microscope Image Data Set and Improving Auto-Encoder Models for Higher Accuracy Segmentation of HaCaT Cell Culture Line." In 2023 5th International Congress on Human-Computer Interaction, Optimization and Robotic Applications (HORA). IEEE, 2023. http://dx.doi.org/10.1109/hora58378.2023.10156778.

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