Relevant bibliographies by topics / Haematological inductions

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Academic literature on the topic 'Haematological inductions'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Haematological inductions"

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Ogbuagu, Dike H., Ikenna N. Nwachukwu, Anthony C. Nwazuluahu, and Nzoputa P. Kalakiya. "Haematotoxicological and hepatotoxic inductions of a geophagic substance (Calabash chalk) on the albino rat (Rattus norvegicus)." Journal of Environmental Toxicology and Public Health 2 (October 13, 2017): 14–26. https://doi.org/10.5281/zenodo.1010453.

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This study investigated probable effects of a geophagic material - <em>Calabash chalk</em> on the haematology and liver enzyme activities of the mammalian model- <em>Rattus norvegicus</em>. Twenty four albino rats were acclimatised and exposed to 12.5, 25.0 and 50.0 % (w/w) toxicant-feed mixture. After 2 weeks, the animals were sacrificed and their blood as well as liver enzyme function activities were assessed. The higher toxicant concentrations induced lower body weights in the mammals [F<sub>(4618.5)</sub>&gt;F<sub>crit(4.30)</sub>] at p&lt;0.05. Mean maximum white blood cell (15.0±8.84x10<
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Lavole, Armelle, Laurent Greillier, Julien Mazières, et al. "First-line carboplatin plus pemetrexed with pemetrexed maintenance in HIV-positive patients with advanced non-squamous non-small cell lung cancer: the phase II IFCT-1001 CHIVA trial." European Respiratory Journal 56, no. 2 (2020): 1902066. http://dx.doi.org/10.1183/13993003.02066-2019.

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HIV infection is an exclusion criterion in lung cancer trials. This multicentre phase II trial aimed to assess feasibility, efficacy and safety of first-line carboplatin plus pemetrexed (CaP) followed by pemetrexed (P) maintenance in people living with HIV (PLHIV) with advanced non-squamous non-small cell lung cancer (NS-NSCLC).Four cycles of CaP were followed by P-maintenance therapy in patients with Eastern Cooperative Oncology Group performance status ≤2. The primary objective was a disease control rate (DCR) ≥30% after 12 weeks.Of the 61 PLHIV enrolled, 49 (80%) had a performance status of
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Utracka-Hutka, B., M. Krzakowski, M. Provencio, et al. "Navelbine (NVB) oral (o) with cisplatin (CDDP) as induction and concomitant to radiotherapy (RT): Final results of an international phase II trial in stage III non-small cell lung cancer (NSCLC)." Journal of Clinical Oncology 25, no. 18_suppl (2007): 7691. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.7691.

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7691 Background: NVB i.v. with CDDP has reported an optimal activity/tolerance ratio when used in combination with RT. The new oral formulation of NVB should be easier to use assuming a similar activity profile. An international phase II trial with NVBo + CDDP as induction followed by NVBo+CDDP+RT was implemented in order to evaluate the efficacy of this combination. Methods: Patients (pts) between 18 and 70 years, with histologically proven untreated locally advanced inoperable stage IIIA/IIIB (supraclavicular LN and pleural effusion excluded) NSCLC, adequate bone marrow, hepatic and renal fu
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Loveikyte, R., P. W. Voorneveld, G. Dijkstra, and A. E. van der Meulen - de Jong. "P923 Haematological abnormalities during treatment with Janus kinase inhibitors in patients with Ulcerative Colitis: a post hoc analysis." Journal of Crohn's and Colitis 18, Supplement_1 (2024): i1681. http://dx.doi.org/10.1093/ecco-jcc/jjad212.1053.

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Abstract Background Janus kinase inhibitors (JAKi) are used for Ulcerative Colitis treatment and could lead to haematological abnormalities, such as anaemia. In this post hoc analysis, we evaluated whether treatment with tofacitinib or filgotinib is associated with anaemia and other haematological laboratory abnormalities. Methods Data from randomized clinical trials [OCATVE 1 (NCT01465763), OCTAVE 2 (NCT01458951), OCTAVE Sustain (NCT01458574), and summary-level data from SELECTION (NCT02914522)] evaluating the efficacy of filgotinib and tofacitinib were used in this post hoc analysis. Adult p
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Yasuhiro, Tomoko, Toshio Yoshizawa, Ryu Fujikawa, Kohei Tanaka, Tomoya Koike, and Kazuhito Kawabata. "Development of an Axl/Mer Dual Inhibitor, ONO-9330547: Promising Single Agent Activity in an Acute Myeloid Leukemia (AML) Model." Blood 124, no. 21 (2014): 999. http://dx.doi.org/10.1182/blood.v124.21.999.999.

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Abstract Purpose: Axl and Mer belong to the TAM (Tyro3, Axl, Mer) family of receptor tyrosine kinases and play a role in regulating cell proliferation, survival, migration and cytokine production. Axl/Mer are over-expressed in various types of haematological and solid tumour cancers and appear to play a key role in epithelial-to-mesenchymal transitions (EMTs), known to be important in tumour metastases and drug resistance. AML is a clonal disease of haematopoietic progenitors characterised by acquired heterogeneous genetic changes that alter cell proliferation and differentiation and Axl is an
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Gooré Guy Charles Golé NANTI, Dago Désiré KOUDOU, Bi Lané Adrien GOH, Bi Semi Anthelme NENE, and Flavien TRAORE. "Impacts of aqueous extracts of Annona senegalensis and Hallea ledermannii on hematological parameters in Wistar rats made diabetic by alloxan induction." World Journal of Advanced Research and Reviews 23, no. 3 (2024): 1156–66. http://dx.doi.org/10.30574/wjarr.2024.23.3.2269.

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Background: The costly treatment of diabetes mellitus is leading low-income populations to turn to phytotherapy, which requires preclinical testing to prevent dangerous side effects. Objective: To evaluate the impact of aqueous extracts of Annona senegalensis (EAAs) and Hallea ledermannii (EAHl) on the haematological parameters of diabetic Wistar rats. Material and methods: Diabetes was induced in normal rats by injection of alloxane. Diabetic rats were treated with the test substances for four (4) and thirteen (13) weeks. Haematological parameters were assayed after these treatments. Results:
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Martino, Bruno, Maria Cuzzola, Carmela Rigolino, et al. "Gene Expression Profile (GEP) Analysis as a Tool to Control the Efficacy Dasatinib Treatment in Relapsed Imatinib-Resistant CML Patients Previously Undergone to Allogeneic Stem Cell Transplantation. Preliminary Data of a Single Institution." Blood 112, no. 11 (2008): 4260. http://dx.doi.org/10.1182/blood.v112.11.4260.4260.

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Abstract Dasatinib was approved for use in the treatment of patients (pts) with chronic myeloid leukaemia (CML) and resistance to Imatinib. We applied a rescue treatment based on Dasatinib therapy to achieve a pharmacological immunomodulation in a setting of CML-relapsed allogenic stem cell transplantated (A-HSCT) pts. Patients were required to have both resistance to Imatinib and unresponsiveness to cellular therapy such as Donor Lymphocyte Induction (DLI). We hypothesized that Dasatinib could potentially improove the disease by immunomodulatory action. Primary aim of this therapeutic design
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Babbar, Nikhil, Gajendra S. Khandekar, Santosh D. Tripathi, Dishant Saini, Shahir V. Gaikwad, and Shalaka A. Chauhan. "Clinical Evaluation of Xylazine-Zoletil Anesthesia in Equine under Field Conditions." Indian Journal of Veterinary Sciences & Biotechnology 19, no. 1 (2023): 77–81. http://dx.doi.org/10.48165/ijvsbt.19.1.17.

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The present study was conducted on eighteen horses divided into three groups, consisting of six horses in each irrespective of their size, breed and body weight. Horses from all groups were pre-anaesthetized with xylazine (1.1 mg/kg b.wt.) intravenously and anesthetized after 5 min with doses of zoletil (Tiletamine and zolazepam) @ 0.5 mg/kg, 0.8 mg/kg and 1.1 mg/kg BW in groups I, II and III, respectively. Evaluation of different parameters like time of induction of anaesthesia, quality of induction, duration of anaesthesia, degree of muscle relaxation, time and quality of recovery were evalu
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Biswas, DS, M. Hasan, S. Mallick, NS Juyena, M. Shoriotullah, and MR Alam. "Clinical and haematological changes upon administration of Xylazine-Ketamine and Xylazine-Thiopentoneanaesthetic combinations in ewes." Bangladesh Veterinarian 34, no. 1 (2018): 9–19. http://dx.doi.org/10.3329/bvet.v34i1.38708.

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The study was done to evaluate the effect of Xylazine-Ketamine and Xylazine- Thiopentone combinations for general anaesthesia in sheep. Six healthy sheep were divided into two groups: Group XK (n = 3), anaesthetized with Xylazine-Ketamine and Group XT (n = 3), anaesthetized with xylazine-thiopentone. Anaesthesia was induced using 1.1 mg/kg xylazine with 10 mg/kg ketamine or 20 mg/kg thiopentone as a single intravenous injection. Induction, duration and recovery from anaesthesia were monitored. Respiratory rate, heart rate and rectal temperature were recorded 15 min before and 5 min after induc
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Gooré, Guy Charles Golé NANTI, Désiré KOUDOU Dago, Lané Adrien GOH Bi, Semi Anthelme NENE Bi, and TRAORE Flavien. "Impacts of aqueous extracts of Annona senegalensis and Hallea ledermannii on hematological parameters in Wistar rats made diabetic by alloxan induction." World Journal of Advanced Research and Reviews 23, no. 3 (2024): 1156–66. https://doi.org/10.5281/zenodo.14942725.

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<strong>Background:&nbsp;</strong>The costly treatment of diabetes mellitus is leading low-income populations to turn to phytotherapy, which requires preclinical testing to prevent dangerous side effects. <strong>Objective</strong>: To evaluate the impact of aqueous extracts of&nbsp;<em>Annona senegalensis</em>&nbsp;(EAAs) and&nbsp;<em>Hallea ledermannii</em>&nbsp;(EAHl) on the haematological parameters of diabetic Wistar rats. <strong>Material and methods:&nbsp;</strong>Diabetes was induced in normal rats by injection of alloxane. Diabetic rats were treated with the test substances for four (
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Book chapters on the topic "Haematological inductions"

1

Corradini, Paolo, and Lorenz Trümper. "Developments in Other Haematological Malignancies: Other Lymphoid Malignancies." In The EBMT/EHA CAR-T Cell Handbook. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94353-0_17.

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AbstractPeripheral T cell lymphomas comprise a heterogeneous group of rare diseases, representing 10–15% of all non-Hodgkin lymphomas (NHLs). Upfront treatment for peripheral T cell lymphoma (pTNHL) includes CHOP-like (cyclophosphamide, adriamycin, vincristine, prednisone) multiagent chemotherapy with or without etoposide, followed by stem cell transplantation as consolidation in responsive fit patients. This approach induces durable long-term remission in approximately 40% of cases; early refractoriness during induction occurs in approximately 25% of patients, with the remaining patients typi
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Demidova, I. A., Y. V. Olshanskaia, L. P. Poreshina, et al. "Induction of Mixed Chimerism in Patients After Non-Myeloablative Stem Cell Transplantation (SCT) for High Risk Haematological Malignancies." In Haematology and Blood Transfusion Hämatologie und Bluttransfusion. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-59358-1_87.

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Al-Foudri, Huda, Stuart Davies, and Abrie Theron. "Obesity in pregnancy." In Obstetric Anaesthesia. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780199688524.003.0016.

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Epidemiological studies show the incidence of obesity in pregnancy to be increasing, and the management of the morbidly obese woman on labour ward can be a challenge for anaesthetists. The chapter defines obesity, body mass index, classification, and prevalence, and reviews the physiological effects of obesity on the respiratory, cardiovascular, gastrointestinal, renal, endocrine, and haematological systems, as well as pharmacokinetic changes. Both fetal and maternal morbidities are listed followed by management proposals in the antenatal, peripartum, and postpartum periods. This includes ante
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Torpey, Nicholas, and John D. Firth. "Renal transplantation." In Oxford Textbook of Medicine, edited by John D. Firth. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0481.

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Renal transplantation is the preferred option for the treatment of endstage chronic renal failure in patients for whom there are no major medical contraindications. In well-selected recipients, both life expectancy and quality of life are superior to treatment with long-term dialysis. However, as the dialysis population continues to grow, the gap between supply and demand for renal transplantation is widening. Immunosuppression—excepting for transplants between HLA-identical twins, immunosuppression is required to prevent rejection, but there is no clear consensus on the best immunosuppressive
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Journal articles
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