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Dissertations / Theses on the topic 'Haemorrhage'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Aquilina, Kristian. "Animal models of intraventricular haemorrhage and post-haemorrhagic ventricular dilatation." Thesis, University of Bristol, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.574598.

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Continuing improvements in neonatal care have allowed significant progress in the clinical outcome of prematurity, with improvement t in both survival and neurological outcome. Although the incidence of intraventricular haemorrhage associated with prematurity has been lowered, it still represents a significant source of neurological morbidity. Several management strategies have attempted to reduce the neurological impact of IVH and its progression to post-haemorrhagic ventricular dilatation (PHVD). Studies have evaluated the impact of serial withdrawal of cerebrospinal fluid (CSD) by lumbar pu

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2

Samarasekera, Neshika Erangi. "Does lobar intracerebral haemorrhage differ from non-lobar intracerebral haemorrhage?" Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/15836.

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Spontaneous (non-traumatic) intracerebral haemorrhage accounts for ~10% of all strokes in Western populations. Investigations may identify intracerebral haemorrhage (ICH) as ‘secondary’ to underlying causes such as tumours or aneurysms, but ~80% of ICHs which have no apparent underlying cause (so-called ‘primary’ ICH) tend to be attributed to small vessel vasculopathies such as arteriolosclerosis or cerebral amyloid angiopathy (CAA), on the basis of an adult’s risk factors and clinical and radiographic features of the ICH. The commonly accepted hypothesis is that CAA contributes to lobar ICH a

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3

Sobowale, Oluwaseun. "Intracerebral haemorrhage and inflammation." Thesis, University of Manchester, 2018. https://www.research.manchester.ac.uk/portal/en/theses/intracerebral-haemorrhage-and-inflammation(7139560f-bd3c-4ff0-b628-f86ffc6477d2).html.

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Intracerebral haemorrhage (ICH) is a significant healthcare concern worldwide. Following ICH, primary injury occurs due to physical injury to neurones and glia as a result of mass effect from the haematoma. Secondary mechanisms of injury include haematoma expansion, toxic effects of the products of coagulation and blood breakdown products and sterile inflammation. Perihaematomal oedema can exacerbate mass effect in the acute and sub-acute phase of ICH. At present, the pathophysiology behind the secondary mechanisms of injury following ICH is not fully understood and this has led to inability t

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4

Garner, Jeffrey Philip. "Resuscitation after blast and haemorrhage." Thesis, University of Newcastle upon Tyne, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.440563.

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5

McEvoy, Andrew William. "Haemostatic studies in subarachnoid haemorrhage." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1444986/.

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Object. The primary objective of this thesis was to establish the pattern of change in haemostatic systems in patients following a subarachnoid haemorrhage (SAH). I hypothesise that following a SAH there is an undefined period of increasing hypercoagulability, which if present would predispose to ischaemic stroke. Methods. This was a prospective, observational study on 67 consecutive patients admitted with a primary diagnosis of SAH. There were 24 males, median age 47.5 years (25-75) and 43 females, median age 53 years (23- 80). Blood was taken at 4 time periods (<48hours, 4-5, 9-10 and 15-16

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6

Belachew, Johanna. "Retained Placenta and Postpartum Haemorrhage." Doctoral thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-246185.

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The aim was to explore the possibility to diagnose retained placental tissue and other placental complications with 3D ultrasound and to investigate the impact of previous caesarean section on placentation in forthcoming pregnancies. 3D ultrasound was used to measure the volumes of the uterine body and cavity in 50 women with uncomplicated deliveries throughout the postpartum period. These volumes were then used as reference, to diagnose retained placental tissue in 25 women with secondary postpartum haemorrhage. All but three of the 25 women had retained placental tissue confirmed at histopat

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7

Krishnan, Kailash. "Outcomes after acute intracerebral haemorrhage." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/43228/.

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Primary Intracerebral haemorrhage is a severe form of stroke with poor prognosis attributed to haematoma characteristics. High blood pressure is present during the acute phase of intracerebral haemorrhage and associated with poor outcome in part through expansion of haematoma. Data from the ‘Efficacy of Nitric Oxide in Stroke trial’ (ENOS) was used to analyse the performance characteristics of qualitative and quantitative descriptors of intracerebral haematoma. The results showed that formal measurement of haemorrhage characteristics and visual estimates are reproducible. Intracerebral haemorr

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8

Budohoski, Karol Paweł. "Cerebral autoregulation and subarachnoid haemorrhage." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648435.

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9

Lindgren, Cecilia. "Subarachnoid haemorrhage : clinical and epidemiological studies." Doctoral thesis, Umeå universitet, Anestesiologi och intensivvård, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-87553.

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Background: Subarachnoid haemorrhage (SAH) is a severe stroke that in 85% of all cases is caused by the rupture of a cerebral aneurysm. The median age at onset is 50-55 years and the overall mortality is approximately 45%.Sufficient cortisol levels are important for survival. After SAH hypothalamic/pituitary blood flow may be hampered this could result in inadequate secretion of cortisol. SAH is also associated with a substantial inflammatory response. Asymmetric dimethyl arginine (ADMA), an endogenous inhibitor of nitric oxide synthase, mediates vasoconstriction and increased ADMA levels may

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10

Naumann, David Nathaniel. "Early microcirculatory dysfunction following traumatic haemorrhage." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8351/.

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Traumatic haemorrhagic shock (THS) is the most frequent cause of preventable death after severe injury. Shock is characterised by inadequate provision of oxygen and substrates to tissues in relation to their requirements, and it is within the microcirculation that this process is regulated. Investigation of the microcirculation is therefore key to understanding the pathological processes following THS. In Part I, some mechanisms of microcirculatory dysfunction following trauma are presented. Endotheliopathy of trauma is associated with poor microcirculatory flow, and occurs within minutes of i

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11

Mjoli, Ntethelelo. "Brain arteriovenous malformations presenting with haemorrhage." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/2886.

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12

Abid, Kamran. "Modulation of inflammation in intracerebral haemorrhage." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/modulation-of-inflammation-in-intracerebral-haemorrhage(1a1793e0-0013-4f6b-9e51-a5c15828a8a5).html.

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Intracerebral Haemorrhage (ICH) exhibits the worst mortality and morbidity of any stroke subtype. There are no efficacious treatments for this condition and little improvement in patient outcome has been noted despite advancements in medical science over the previous three decades. Furthermore, current available data is increasingly obsolete as the population suffering the disease burden rapidly ages and develops co-morbidities. It is thought that future therapies for this condition may be able to target neuroinflammatory response triggered by the formation of brain haemorrhage however there i

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13

Hales, Majella. "Postoperative antifibrinolytic drugs to control haemorrhage." Thesis, Queensland University of Technology, 2002.

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14

Church, Nicholas I. "Endoscopic therapy for major peptic ulcer haemorrhage." Thesis, University of Edinburgh, 2004. http://hdl.handle.net/1842/24456.

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This thesis is based on a randomized, placebo controlled trial comparing heater probe plus thrombin injection with heater probe plus placebo injection for the treatment of high-risk patients with peptic ulcer bleeding. Two hundred and fifty six patients were randomized. There were nine protocol violations, and these were excluded from the analysis. One hundred and twenty seven patients were treated with the heater probe plus thrombin injection; the remainder received heater probe plus placebo injection. Re-bleeding developed in 9 (15%) of thrombin plus heater probe and 17 (15%) of placebo plus

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15

Nandra, Kiran Kaur. "Novel therapeutic approaches for experimental trauma-haemorrhage." Thesis, Queen Mary, University of London, 2013. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8470.

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Haemorrhagic shock (HS) is commonly associated with trauma. Severe haemorrhage causes hypoperfusion of tissues resulting in a global ischaemic state, and resuscitation is performed to restore circulating volume. However, the return of oxygen to ischaemic tissues causes the induction of a systemic inflammatory response, which contributes to cell death leading to organ failure. In trauma patients, failure of more than four organs is linked to certain mortality, highlighting the need for interventions that may reduce or prevent the deterioration in organ function. The aim of this thesis was to in

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16

Morrison, Jonathan James. "Resuscitative endovascular haemorrhage control in wartime injury." Thesis, University of Glasgow, 2014. http://theses.gla.ac.uk/5669/.

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Non-compressible haemorrhage from within the torso and junctional regions constitutes the leading cause of potentially preventable death on the battlefield. It can be defined as haemorrhagic shock arising from injury to named torso vessels, pulmonary parenchyma, high grade solid organ injury and/or disruption of the bony pelvis. Data from the US Department of Defence Trauma Registry demonstrate a torso injury rate of 12.7% with 17.1% of casualties exhibiting torso injury and shock. The overall mortality is 18.7%, with major arterial injury and pulmonary injury identified as independent predict

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17

Curry, Nicola Suzanne. "The coagulopathy of trauma related major haemorrhage." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608299.

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18

Garden, O. James. "Prediction of outcome following acute variceal haemorrhage." Thesis, University of Edinburgh, 1986. http://hdl.handle.net/1842/18218.

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Between August 1979 and September 1982, acute variceal haemorrhage has been managed in the University Department of Surgery, Glasgow Royal Infirmary by a policy of oesophageal tamponade and injection sclerotherapy. Haemorrhage was controlled in 90% of admissions with an admission mortality of 28%. Recurrent haemorrhage occurred in half the patients surviving their first admission to hospital despite entering a programme of elective sclerotherapy. The results of this management policy are reviewed and the means of selecting patients for more aggressive therapy discussed. The deficiencies of a m

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19

Tooth, Claire L. "Outcome following neurosurgical treatment of aneurysmal subarachnoid haemorrhage." Thesis, University of Sheffield, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.421001.

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20

Roos, Yvo Benjamin Walther Elisabeth Maria. "Fibrinolysis and antifibrinolytic treatment in aneurysmal subarachnoid haemorrhage." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2000. http://dare.uva.nl/document/55676.

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21

Wheatley, K. E. "Peptic ulcer haemorrhage : the role of intragastric fibrinolysis." Thesis, University of Newcastle Upon Tyne, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308741.

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22

Sinha, S. K. "Vitamin E and periventicular haemorrhage in preterm babies." Thesis, University of Manchester, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234205.

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23

Tait, Matthew James. "The role of aquaporin-4 in subarachnoid haemorrhage." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:9b50df6f-9949-4ac2-a920-c1f44872aeb1.

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Introduction. The glial cell water channel aquaporin-4 (AQP4) plays an important ro le in brain oedema, astrocyte migration and neuronal excitability. Current theories of AQP4 function are based largely on experiments using AQP4 -1- mice. These mice have only been partially characterized. I therefore undertook a detailed investigation of baseline brain properties in AQP4 -1- mice. In the second part of my experiments I investigated the role of AQP4 in brain oedema in a mouse model of subarachnoid haemorrhage. Method. Gross anatomical measurements included estimates of brain and ventricle size.

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24

Fullarton, Grant M. "Studies on the pathophysiology of upper gastrointestinal haemorrhage." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/18895.

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25

Menezes, Kevin Gerard. "A computer model of acute haemorrhage and resuscitation." Thesis, University of Aberdeen, 1998. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU114245.

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Acute haemorrhage cases are extremely difficult to analyse using randomised experimental studies and are well suited to computer modelling. The two main areas of current research are whether intravenous fluids should be administered to patients at the scene of an accident or not and what type of fluid should be given. A computer model was designed which analyses the fluid volume compartments within the human body. The relationship between the blood volume and blood pressure was examined, as was the transcipillary refill effect and the mechanics of the bleeding site. The model was then validate

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26

Brooke, Nicholas S. R. "The study of human cerebral metabolism using 31-phosphorus magnetic resonance spectroscopy." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364064.

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27

Lentsoane, Tiisotso Lenake. "Intraventricular haemorrhage in premature babies at Dr George Mukhari Hospital, Pretoria." Thesis, University of Limpopo (Medunsa Campus), 2011. http://hdl.handle.net/10386/670.

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Thesis MSc.(Med)(Virology)-- University of Limpopo, 2011<br>Background: Intraventricular hemorrhage (IVH) is a known complication occurring in the first week of life in premature neonates. The exact time of its occurrence and the ideal time to perform diagnostic imaging investigation remain controversial. Objectives: 1. To determine the incidence of intraventicular hemorrhage in premature babies at Dr George Mukhari Hospital, Pretoria. 2. To determine the timing at which bleeding occurs. 3. To determine if the rate of diagnosing intraventicular hemorrhage improves when performing ultraso

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28

Zetterling, Maria. "Clinical Studies in the Acute Phase of Subarachnoid Haemorrhage." Doctoral thesis, Uppsala universitet, Neurokirurgi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-129160.

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Patients admitted in similar clinical condition after spontaneous SAH can develop very different clinical courses. This could depend on the severity of the initial global ischemic brain injury at ictus. In the present study, we explored relations between clinical and radiological parameters at admission that indicate a more severe initial impact, and the following days hormone levels and brain metabolism. Early global cerebral oedema (GCE) on computed tomography occurred in 57 % of SAH patients and was associated with a more severe clinical condition. The brain’s glucose metabolism, measured w

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29

Domingo, Zayne. "Ischaemia following subarachnoid haemorrhage : magnetic resonance spectroscopy and imaging." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360214.

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30

Jacobs, Neal. "Novel resuscitation strategies for casualties of blast and haemorrhage." Thesis, University of Newcastle Upon Tyne, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556122.

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Blast injury is a dominant and increasing mode of battlefield injuries. The resulting complex injury pattern may include hypoxia due to primary blast lung injury and haemorrhage due to severe secondary and tertiary blast injuries. It has been previously shown that hypotensive resuscitation, as recommended by NICE for pre-hospital trauma resuscitation, is not compatible with survival over extended evacuation times following combined blast injury and haemorrhage, due to underlying inadequacy of systemic tissue oxygen delivery. This thesis investigates a hybrid resuscitation strategy, utilising a

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31

McMahon, Catherine Jane. "Inflammation and delayed cerebral ischaemia induced byaneurysmal subarachnoid haemorrhage." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491335.

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Stroke is a sudden, unpredictable, often devastating neurological event. The commonest cause of morbidity and mortality associated with subarachnoid haemorrhage (SAH) is delayed cerebral ischaemia (DCI). Ischaemic and haemorrhagic strokes are recognised to induce a significant peripheral and central inflammatory response. These responses may be important in the exacerbation of ischaemic damage and in the development and exacerbation of DCI after SAH. A number of studies have examined the potential contribution of pro-inflammatory cytokines, such as interleukin-l (IL-l) and interleukin-6 (IL-6)

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32

Estcourt, Lise Jane. "Risk factors for haemorrhage in patients with haematological malignancies." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:4efbd9b1-62e5-4536-a5ee-df5eea4620d0.

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Haematological malignancies and their treatment lead to prolonged periods of severe thrombocytopenia (platelet count ≤ 50 x 10<sup>9</sup>/l). Despite the use of prophylactic platelet transfusions, haemorrhage remains an important complication during this thrombocytopenic period. Within a 30 day period up to 70% of patients have clinically significant haemorrhage (World Health Organization (WHO) grade 2 or above bleeding) and up to 10% have severe or life-threatening haemorrhage (WHO grade 3 or 4 bleeding). Hence our current management of these patients to prevent haemorrhage is sub-optimal. T

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33

Wang, Xia. "Rapid blood pressure lowering treatment in acute intracerebral haemorrhage." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/15431.

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Acute spontaneous intracerebral haemorrhage (ICH) occurs when a diseased blood vessel ruptures within the brain, allowing blood to track inside the brain to damage tissues and raise intracranial pressure from the mass effect of the resulting haematoma. ICH is less common than acute ischaemic stroke due to occlusion of an intracerebral vessel, accounting for between 10% and 35% of strokes according to the at-risk population. Temporal trends in the incidence of ICH appear stable and its prevalence is increasing in aging populations. The high burden of premature death and disability associated wi

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34

Dawes, William John. "Neural stem cells as therapeutic targets in germinal matrix haemorrhage." Thesis, Queen Mary, University of London, 2017. http://qmro.qmul.ac.uk/xmlui/handle/123456789/24869.

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Haemorrhage within the germinal matrix with extension into the ventricle is commonly seen in very low birth weight babies. Outcome following severe haemorrhage, in particular when associated with post haemorrhagic hydrocephalus and congestive venous infarction is poor, whilst outcome following moderate degrees of haemorrhage remains variable. The Neural Stem Progenitor Cells (NSPC) within the GM have been shown to be exquisitely sensitive to micro-environmental cues, as such, haemorrhage within the GM is postulated to impact on neurological outcome through aberration of normal NSPC behaviour.

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35

Horne, Margaret Anne. "Investigating the risk of intracranial haemorrhage or focal neurological deficit in adults diagnosed with cerebral cavernous malformation." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/15879.

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Background A cerebral cavernous malformation (CCM) is a small cluster of thin-walled, dilated blood vessels within the brain which is prone to bleed. Although the quantity of blood leaking tends to be small, even a small intracranial haemorrhage (ICH) can result in a clinically significant neurological deficit. Because some focal neurological deficits (FND) may in fact be haemorrhages that were undetected by imaging, FND were also included in the analysis wherever possible. In Scotland, between 2006 and 2010, the annual CCM detection rate was 0.8 per 100,000 people. Since estimates of prognosi

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36

Brookes, Zoe L. S. "The effects of haemorrhage on the microcirculation during intravenous anaesthesia." Thesis, University of Sheffield, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327629.

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37

Galea, James. "Pharmacokinetics of intravenous interleukin-1 receptor antagonist in subarachnoid haemorrhage." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509780.

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38

Clarke, Samantha A. "Increased body temperature following subarachnoid haemorrhage : a retrospective correlational study." Thesis, Queensland University of Technology, 2009. https://eprints.qut.edu.au/26542/1/Samantha_Clarke_Thesis.pdf.

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Introduction: Nursing clinicians are primarily responsible for the monitoring and treatment of increased body temperature. The body temperature of patients during their acute care hospital stay is measured at regular repeated intervals. In the event a patient is assessed with an elevated temperature, a multitude of decisions are required. The action of instigating temperature reducing strategies is based upon the assumption that elevated temperature is harmful and that the strategy employed will have some beneficial effect. Background and Significance: The potential harmful effects of in

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Clarke, Samantha A. "Increased body temperature following subarachnoid haemorrhage : a retrospective correlational study." Queensland University of Technology, 2009. http://eprints.qut.edu.au/26542/.

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Introduction: Nursing clinicians are primarily responsible for the monitoring and treatment of increased body temperature. The body temperature of patients during their acute care hospital stay is measured at regular repeated intervals. In the event a patient is assessed with an elevated temperature, a multitude of decisions are required. The action of instigating temperature reducing strategies is based upon the assumption that elevated temperature is harmful and that the strategy employed will have some beneficial effect. Background and Significance: The potential harmful effects of in

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40

Dreier, Jens P. "Cortical spreading ischaemia and delayed ischaemic neurological deficits after subarachnoid haemorrhage." Doctoral thesis, [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=970109342.

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41

Gill, Navjot. "Long-term functional and neuropsychological outcomes of subarachnoid haemorrhage (SAH) survivors." Thesis, University of Auckland, 2011. http://hdl.handle.net/2292/6879.

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Stroke is the second commonest cause of death worldwide and the most frequent cause of disability in adults. Although Subarachnoid Haemorrhage (SAH) accounts for a small percentage of stroke, it impacts people at a younger age and with debilitating consequences, in the areas of mood, functioning and cognitive deficits which may persist for years after the SAH. However, very little research has been done to examine the long-term (beyond 1-3 years) outcomes of SAH. Furthermore, previous studies have not been population based, nor have they examined the impact of long-term cognitive outcomes usin

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42

Dinh, The Trung. "Pathogenesis of haemorrhage associated with dengue infection in adults in Vietnam." Thesis, Open University, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.576668.

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Clinical experience suggests that adults with dengue manifest a pattern of complications different from those observed in children, but direct comparisons among populations experiencing the same exposure have rarely been published. I conducted a large prospective descriptive study of dengue across all age-groups presenting to a single institution in an endemic country during a defined time-period. Vascular leakage was more severe in the paediatric patients and DSS developed much more frequently in this age-group. In contrast haemorrhagic manifestations and severe organ involvement were more co

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43

Morris, Paul Graham. "Long-term neuropsychological outcome following subarachnoid haemorrhage or traumatic brain injury." Thesis, University of Stirling, 2001. http://hdl.handle.net/1893/1877.

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Purpose: The principal aim of this project was to investigate the influence of clinical indices of injury severity and polymorphism of the apolipoprotein E gene upon the long-term physical, cognitive and emotional sequelae of traumatic brain injury and spontaneous subarachnoid haemorrhage. It was also intended to determine the extent to which changes occur in these sequelae beyond the initial six months post injury. Method: Sixty-two brain injury patients who had previously taken part in a neuropsychological assessment at six months post injury were traced and participated in a follow-up asses

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44

Doran, Catherine Margaret. "Effect of resuscitation strategies on coagulation following haemorrhage and blast exposure." Thesis, University of Newcastle upon Tyne, 2013. http://hdl.handle.net/10443/1868.

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Approximately one-third of trauma patients are coagulopathic on arrival to the emergency department. Acute traumatic coagulopathy and systemic inflammatory responses are serious secondary consequences of severe trauma and are linked to increased morbidity and mortality. Early tissue hypoxia is a major component in the aetiology of both complications. New resuscitation strategies are aimed at improving tissue oxygenation in the pre-hospital phase, and may attenuate coagulopathy and inflammatory sequelae. This is of particular importance in military personnel who suffer complex injuries, often f

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45

Charidimou, A. "Applied clinical neuroimaging in cerebral amyloid angiopathy and spontaneous intracerebral haemorrhage." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1461023/.

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Sporadic cerebral amyloid angiopathy is a common small vessel disease that preferentially involves small cortical and leptomeningeal arteries due to progressive amyloid-β deposition in their walls. Cerebral amyloid angiopathy occurs frequently in elderly people, and is a common and important cause of symptomatic lobar intracerebral haemorrhage and cognitive impairment. There is currently a growing interest in cerebral amyloid angiopathy, at least partly thanks neuroimaging, which now allows an unprecedented ability to investigate the disease dynamics in vivo using MRI to reveal complex pattern

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46

Zarros, Apostolos. "Development and assessment of in vitro simulation approaches to intracerebral haemorrhage." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8119/.

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This current PhD Thesis in Neuropathology focuses on the development and assessment of in vitro simulation approaches to intracerebral haemorrhage. The PhD Thesis provides a clinical and experimental neuropathological overview of intracerebral haemorrhage as well as an account of the in vitro simulation approaches to the disease, before proceeding to the presentation of the experimental work designed and performed by the author. The development of the herein presented in vitro simulation approaches to intracerebral haemorrhage was based on the use of an immortalized embryonic murine hippocampa

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47

Hreash, Fatma. "The cardiovascular effects of vasopressin following acute haemorrhage in anaesthetized rats." Thesis, Imperial College London, 1988. http://hdl.handle.net/10044/1/47113.

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48

Hellawell, Deborah Jane. "Cognitive and funtional outcome following traumatic brain injury or subarachnoid haemorrhage." Thesis, University of Edinburgh, 1998. http://hdl.handle.net/1842/21299.

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The present study was designed to investigate the outcome of 100 surviving patients who were admitted consecutively to a regional neurosurgical unit with a diagnosis of either moderate or severe TBI. An additional group of 44 SAH patients was recruited to enable tentative comparisons to be drawn between groups with acute brain injury arising from these different causes. At intervals of 6, 12 and 24 months post-injury, global outcome was estimated using the Glasgow Outcome Scale (GOS) and patients were assessed using a battery of neuropsychological tests. Information concerning the extent of th

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49

Chaudery, Muzzafer. "A reflection of pre-hospital imaging on traumatic intra-abdominal haemorrhage." Thesis, Imperial College London, 2016. http://hdl.handle.net/10044/1/47965.

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Torso haemorrhage remains one of the leading causes of preventable morbidity and mortality from trauma particularly in the prehospital setting. Early identification of the haemorrhage source is essential in order to improve outcomes and an effective imaging modality may help to establish the diagnosis. This thesis examines how to improve abdominal haemorrhage identification in the prehospital setting in order to achieve rapid haemorrhage control. The current literature is appraised and a national questionnaire distributed to frontline trauma care physicians. For haemorrhage identification rese

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Abdul-Kadir, Rezan Ahmed. "Inherited bleeding disorders in obstetrics and gynaecology." Thesis, University of London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391628.

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