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1

Provenat, Véronique. "Les effets toxiques et allergiques de l'halothane." Paris 5, 1989. http://www.theses.fr/1989PA05P046.

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2

Zhang, Ke. "Cardiac electrophysiology and cardiotoxicity of halothane /." The Ohio State University, 1989. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487676261012213.

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3

Knight, Trudy Lynn. "The molecular basis of halothane-induced hepatotoxicity." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321782.

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4

Siadat, Pajouh Majid 1959. "GENERATION OF HALOTHANE INDUCED ANTIBODY IN GUINEA PIGS AND ITS POSSIBLE ROLE IN THE PATHOGENESIS OF HALOTHANE INDUCED LIVER INJURY." Thesis, The University of Arizona, 1986. http://hdl.handle.net/10150/276363.

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5

LAUNAY, FREDERIC. "Toxicologie de l'halothane." Strasbourg 1, 1991. http://www.theses.fr/1991STR15020.

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6

Molliex, Serge. "Effets de l'halothane sur les pneumocytes II de rat en culture primaire." Saint-Etienne, 1991. http://www.theses.fr/1991STET6417.

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7

Vinh, Vu Huu. "Comparative contractile effects of halothane and sevoflurane in rat aorta." Kyoto University, 2001. http://hdl.handle.net/2433/150545.

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8

Goddard, Helen. "Electrophysiological effects of fentanyl, halothane and isoflurane on guinea-pig isolated ventricular myocytes." Thesis, University of Oxford, 2002. http://ora.ox.ac.uk/objects/uuid:58f6f4e2-aaa9-4913-a7c2-5568e2f8d72f.

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9

Torske, Kristine E. "An evaluation of epidural oxymorphone and bupivacaine during halothane anesthesia in dogs." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0026/NQ31906.pdf.

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10

Darling, John R. "The effects of halothane, isoflurane and sevoflurane on hepatic and renal function." Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261937.

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11

Southwood, Olwen Irene. "Studies on the genetics and dynamics of the halothane gene in pigs." Thesis, University of Edinburgh, 1986. http://hdl.handle.net/1842/14460.

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12

Harris, Natalie K. "Gas detection using semiconducting polymers." Thesis, University of Manchester, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262652.

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13

Gérard, Alain. "Determination des caracteristiques cliniques de la crise d'hyperthermie maligne per-anesthesique : analyse d'une serie de 95 propositus classes par les tests de contracture halothane et cafeine." Lille 2, 1994. http://www.theses.fr/1994LIL2M147.

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14

Brown, Alan Perry. "Generation and expression of halothane derived protein adducts in the guinea pig liver." Diss., The University of Arizona, 1993. http://hdl.handle.net/10150/186218.

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The volatile anesthetic halothane can be bioactivated in the liver to the reactive intermediate, trifluoroacetyl chloride, which is capable of covalently modifying liver protein. The product of this reaction is trifluoroacetyl-N-ε-amino lysine, which can act as a foreign epitope in altering both protein immunogenicity and antigenicity. Protein adduct formation appears to be responsible for the development of both an acute and an immune-mediated hepatotoxicity. The goal of this research project was to detect, quantify, and characterize the formation of protein adducts in the guinea pig liver, f
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15

Lyons, Jeremy D. M. "Effects of anaesthesia and nutrition on immunology and hepatic function in adults and children." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326386.

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16

Sassou-Toussaint, Etchrivi. "Effet de l'halothane sur les propriétés mécaniques intrinsèques du muscle squelettique : application à l'hyperthermie maligne." Lille 1, 1995. http://www.theses.fr/1995LIL10054.

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L'hyperthermie maligne (hm) est une myopathie génétiquement déterminée. L'anomalie génétique est situé sur le chromosome 19 (locus q12-13. 2) proche de celui codant pour le récepteur à la ryanodine. La susceptibilité à l'hm est dépistée par des tests de contracture musculaire halothane-caféine réalisés in vitro sur des biopsies musculaires. La première partie de cette étude a permis de mettre en évidence la relation qui existe entre la contracture et les paramètres mécaniques du couplage contraction-relaxation et leurs modifications respectives chez le muscle squelettique sensible à l'hm. Nous
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17

Onimus, Jerome. "Dose test en anesthesie locoregionale pediatrique : evaluation de la lidocaine 1 % adrenalinee chez l'enfant anesthesie par halothane." Lille 2, 1994. http://www.theses.fr/1994LIL2M272.

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18

Wodey, Eric. "Role de la po2 dans la toxicite hepatique de l'halothane : etude sur primoculture d'hepatocyte de rat." Rennes 1, 1992. http://www.theses.fr/1992REN1M131.

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19

Chiari, Pascal. "Effets cardiovasculaires du propofol : a propos d'une etude experimentale ; effets sur les debits sanguins regionaux et l'hemodynamique globale et regionale myocardique compares a l'halothane chez le chien." Lyon 1, 1993. http://www.theses.fr/1993LYO1M258.

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20

Heyer, Laurent. "Effets respiratoires du propofol et de l'halothane chez le jeune enfant." Lyon 1, 1993. http://www.theses.fr/1993LYO1M336.

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21

Jaramillo, Cárdenas Jairo [UNESP]. "Estudo comparativo entre a lindocaína e a acupuntura no tratamento da taquicardia ventricular induzida com infusão contínua de dopamina em equinos sob anestesia geral com halotano." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/103779.

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Made available in DSpace on 2014-06-11T19:32:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-02Bitstream added on 2014-06-13T18:44:21Z : No. of bitstreams: 1 jaramillocardenas_j_dr_botfmvz.pdf: 242577 bytes, checksum: 5dcc866f1ed70acb337558dd3e761c21 (MD5)<br>Universidade Estadual Paulista (UNESP)<br>A alta mortalidade relacionada a anestesia na espécie eqüina em relação à outras espécies, se deve principalmente à depressão cardiovascular. A taquicardia ventricular (TV) é uma das possíveis arritmias observadas durante a anestesia, classicamente tratada com lidocaina. Objetivou-se a
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22

Giovanelli, Debora. "Electrochemical detection of gases." Thesis, University of Oxford, 2004. http://ora.ox.ac.uk/objects/uuid:fd447153-b6dd-4be1-aae5-4ece5dc36856.

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This thesis discusses diverse electrochemical strategies for the determination of the concentration of the gases hydrogen sulfide, ammonia and halothane. The chemical tagging of sulfide by a variety of structurally diverse substituted benzoquinone species was studied over a wide range of pH (2<pH<10). Each derivative was found to respond to increasing concentration of sulfide (typically over a range 10-200 μM). The electrochemically initiated reaction of N,N-diethyl-pphenylenediamine (DEPD) with sulfide in N,N-dimethylformamide (DMF) was next examined with quantitative detection of sulfide (li
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23

Khazzaka, Aline. "Les protéines de choc thermique-70 kDa (HSPs 70) chez le porc suite à un stress." Lyon 1, 2006. http://www.theses.fr/2006LYO10186.

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Les protéines de choc thermique (hsps) sont des familles de protéines parfaitememnt conservées à travers l'évolution des sxpèces, induites par un choc thermique ou bien par d'autres stresseurs environnementaux. Ce sont des chaperons moléculaires, elles protègent les cellules du stress et facilitent le reploiement et la maturation des protéines cellulaires. Le présent travail consite à étudier la réponse au stress des hsps 70 chez le porc de génotypes NN, Nn et nn au locus halothane (HAL) au niveau sanguin, musculaire et cellulaire. In vitro, le génotype HAL affecte la réponse hsps 70 à tous le
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24

David, Jean-Stéphane. "Étude in vitro de l'effet sur myocarde sain et pathologique d'agents de l'anesthésie." Lyon 1, 2006. http://www.theses.fr/2006LYO10034.

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Les effets de différents produits de l'anesthésie ont été étudiés à l'aide d'un modèle de muscle papillaire. Chez le rat, la protamine a induit un effet inotrope négatif marqué qui s'accompagnait d'une contracture du muscle probablement en relation avec une surcharge calcique intracytosolique. De plus, la réponse inotrope aux agonistes α- et β- adrénergiques était abolie alors que la réponse lusitrope était préservée, suggérant une action en aval de la chaine des phosphorylations AMPc dépendante. Sur le myocarde diabétique, l'effet des gaz halogénés était plus important et en relation avec une
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25

Green, Brent Kenneth II. "The Effects of Genotype, Chromium Picolinate Supplementation, Sex, and Their Interactions on Growth Performance, Carcass Characteristics, and Muscle Quality in Pigs." Thesis, Virginia Tech, 1997. http://hdl.handle.net/10919/35853.

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Two trials (n = 160) were conducted to evaluate the effects of the halothane gene, chromium picolinate supplementation, and sex on growth performance, carcass characteristics, and meat quality in pigs. Halothane negative (NN) and halothane carrier (Nn) pigs (barrows, gilts) were supplemented with either 0 or 200 ppb chromium picolinate from 28.7 to 107.3 kg. There were no differences between genotypes for ADG or G/F. Chromium had no significant effect on any growth, carcass, or muscle quality characteristics, although chromium-fed pigs were slightly fatter. <p> Barrows gained faster (P <
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26

McKinney, Maurice Stanley. "Aspects of cardiac function and the influence of age during anaesthesia with isoflurane and halothane." Thesis, Queen's University Belfast, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333778.

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27

Kobata, Robert Steven 1954. "AN AUTOMATED METHOD OF MEASURING ISOLATED MUSCLE CONTRACTION (VERAPAMIL, HALOTHANE, CALCIUM-CHLORIDE, MAGNESIUM SULFATE, GUINEA PIG)." Thesis, The University of Arizona, 1986. http://hdl.handle.net/10150/277003.

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28

Jaramillo, Cárdenas Jairo. "Estudo comparativo entre a lindocaína e a acupuntura no tratamento da taquicardia ventricular induzida com infusão contínua de dopamina em equinos sob anestesia geral com halotano /." Botucatu : [s.n.], 2006. http://hdl.handle.net/11449/103779.

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Orientador: Stelio Pacca Loureiro Luna<br>Banca: Denise Saretta Schwartz<br>Banca: Denise Fantoni<br>Banca: Renata Navarro Cassu<br>Banca: Francisco Teixeira Neto<br>Resumo: A alta mortalidade relacionada a anestesia na espécie eqüina em relação à outras espécies, se deve principalmente à depressão cardiovascular. A taquicardia ventricular (TV) é uma das possíveis arritmias observadas durante a anestesia, classicamente tratada com lidocaina. Objetivou-se avaliar os efeitos cardiorrespiratórios da TV induzida por dopamina, na anestesia por halotano em eqüinos, comparando o efeito da lidocaina e
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29

Pottie, Robert George. "A CLINICAL STUDY OF INHALANT ANAESTHESIA IN DOGS." University of Sydney, 2004. http://hdl.handle.net/2123/559.

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A clinical trial was undertaken using three different inhalant anaesthetic agents and one intravenous anaesthetic agent in dogs undergoing routine desexing surgery. Healthy adult dogs undergoing either ovariohysterectomy or castration were assessed as to their demeanour, with the more excitable dogs being placed in groups receiving premedication with acepromazine and morphine. All dogs were then randomly assigned an anaesthetic agent for induction of general anaesthesia. The agents were the inhalants halothane, isoflurane and sevoflurane, and the intravenous agent propofol. Inhalant inductio
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30

Baudy, Yves. "L'examen ophtalmologique sous anesthésie générale de courte durée chez l'enfant." Montpellier 1, 1989. http://www.theses.fr/1989MON11156.

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31

Juvin, Philippe. "Régulation du métabolisme des pneumocytes II : effets des halogénés et des particules diesel." Paris 7, 2001. http://www.theses.fr/2001PA077263.

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32

Gatecel, Claire. "Incidence de l'halothane et de l'isoflurane sur les debits sanguins arteriels hepatiques et veineux porte chez l'homme mesures par methode doppler pulse avec microcapteurs implantes : validation de la methode." Rennes 1, 1992. http://www.theses.fr/1992REN1M022.

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33

Ito, Tatsuya. "Reversible inhibition of hypoxia-inducible factor 1 activation by exposure of hypoxic cells to the volatile anesthetic halothane." Kyoto University, 2002. http://hdl.handle.net/2433/149718.

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34

Sobair, Abbas Taha Hamza. "The influence of body temperature on MAC of halothane in the rabbit determined using controlled mechanical and heat stimulation." Thesis, University of Edinburgh, 1995. http://hdl.handle.net/1842/30002.

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The determination of the minimum alveolar concentration (MAC) of any inhalation anaesthetic requires repeated application of the stimulus. The investigation of the influence of body temperature on MAC in the same animal, requires even more applications of the stimulus. The use of what is commonly known as a "supramaximal stimulus", beyond which there is no increase in MAC with any further increase in stimulus intensity, is generally held to provide for the reproducibility of MAC. However, there are many conflicting reports with regard to the MAC values obtained using "supramaximal stimuli" and
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35

Freeman, Lisa C. "The effects of halothane on impulse propagation in Purkinje fibers and across the Purkinje-muscle junction during [alpha]-adrenergic stimulation /." The Ohio State University, 1989. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487673114114476.

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36

Hashiguchi(Ikeda), Mitsuko. "Halothane inhibits an intermediate conductance Ca[2+]-activated K[+] channel by acting at the extracellular side of the ionic pore." Kyoto University, 2004. http://hdl.handle.net/2433/145289.

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37

Nyström, Per-Erik. "Quantitative trait loci in pig production /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5712-2.pdf.

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38

Júnior, Ewaldo de Mattos. "Avaliação biespectral, cardiorrespiratória e hemogasométrica em cadelas submetidas a ovariosalpingohisterectomia, tratadas com acepromazina associada ou não a meperidina e anestesiadas com halotano, isofluorano ou sevofluorano." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/10/10137/tde-17112008-153956/.

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O presente estudo teve como objetivo avaliar os efeitos do halotano, isofluorano e sevofluorano sobre o índice biespectral, parâmetros cardiorrespiratórios e hemogasométricos em cadelas submetidas a ovariosalpingohisterectomia. Foram utilizadas 48 cadelas, sem raça definida, com peso médio de 15,09±4,29 kg, com idade média de 3,9±1,23 anos, encaminhadas para realização do procedimento de orivariosalpingohisterectomia. Os animais foram distribuídos aleatoriamente em seis grupos de oito animais, sendo designados como AH, AMH, AI, AMI, AS e AMS. Os animais dos grupos AH, AI e AS receberam aceprom
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39

Gray, Deborah Lynn. "The effects of cocaine and two major metabolites on epinephrine induced cardiac arrhythmias, electrocardiographic parameters, and mortality in halothane anesthetized male Sprague-Dawley rats /." The Ohio State University, 1990. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487682558446853.

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40

Mercier, Frédéric. "Anesthésiques halogènes et réactivité bronchique : étude chez le cobaye et chez l'homme." Paris 5, 2002. http://www.theses.fr/2001PA05WO72.

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L'halothane, l'isolflurane et le sévoflurane sont de puissants bronchodilatateurs chez l'animal et chez l'homme. Néanmoins, ces effets n'ont jamais été étudiés lors du réveil anesthésique, bien qu'une hyporéactivité trachéale in vitro ait été suggérée chez l'animal après une anesthésie générale. Le desflurane est un bronchodilatateur chez l'animal mais pas chez l'homme ; aucune étude n'a été réalisée sur la bronche humaine isolée jusqu'à présent. Dans la première publication, nous avons étudié 7 sujets asthmatiques deux fois et à une semaine d'intervalle. Un test à la méthacholine a été effect
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41

Kaikarienė, Veslava. "Laukinių ir naminių kiaulių HAL geno tyrimas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140305_141919-10643.

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Šiuo tyrimo tikslas buvo ištirti laukinių ir naminių kiaulių halotano geną. Tyrimo metodika. Tyrimas atliktas 2012-2013 m. LSMU Biologinių sistemų ir genetinių tyrimų institute K. Janušausko gyvūnų genetikos laboratorijoje. Viso, HAL geno atžvilgiu, ištirta 137 kiaulė (45 šernai, 5 Vietnamietiškos kiaulės, 12 Pekariai, 25 Landrasai, 25 Jorkšyrai ir 25 Pjetrėnai). Kiaulių šeriai buvo naudojami kaip genetinės medžiagos šaltinis. Halotano geno nustatymui buvo atliekama polomerazės grandininės reakcija (PGR). HAL geno įtakai mėsinėms ir penėjimosi savybėms įvertinti buvo atrinkti mišrūnai LxJxP
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42

Yerle-Bouissou, Martine. "Contribution à la carte génique du porc par hybridation moléculaire in situ sur des chromosomes en métaphase et en fin de prophase : application à l'étude du gène halothane." Toulouse, INSA, 1990. http://www.theses.fr/1990ISAT0018.

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L'analyse du genome chez l'homme et la souris est maintenant tres avancee grace a l'etablissement de cartes geniques detaillees. La situation est tout a fait differente dans le cas des especes domestiques ou les cartes geniques sont encore sommaires ou inexistantes. L'objectif de ce travail est d'une part, de contribuer a l'etablissement d'une carte physique globale pour l'espece porcine et d'autre part, de realiser la carte fine du chromosome 6, qui porte un gene d'interet zootechnique: le gene de sensibilite a l'halothane (hal). Nous avons etabli le caryotype des chromosomes porcins en fin d
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43

Freitag, F?bio Batista. "Encoding mechanisms based on fast oscillations in the retina of the cat and their dependencies on anesthesia." Universidade Federal do Rio Grande do Norte, 2013. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17028.

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Made available in DSpace on 2014-12-17T15:28:53Z (GMT). No. of bitstreams: 1 FabioBF_DISSERT.pdf: 6339300 bytes, checksum: d864db11d9029d4bcca9a2aaf6e2f131 (MD5) Previous issue date: 2013-08-27<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior<br>Processing in the visual system starts in the retina. Its complex network of cells with different properties enables for parallel encoding and transmission of visual information to the lateral geniculate nucleus (LGN) and to the cortex. In the retina, it has been shown that responses are often accompanied by fast synchronous oscillation
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44

Gueugniaud, Pierre-Yves. "Contractilité myocardique et agents anesthésiques halogénés : de l'étude expérimentale in vitro à l'approche clinique par débitmétrie aortique écho-Doppler." Lyon 1, 1998. http://www.theses.fr/1998LYO1T221.

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45

Saunier, Claude François. "Interactions entre l'anesthésie générale et le système noradrénergique du Locus Coeruleus : approche expérimentale chez le rat." Lyon 1, 1997. http://www.theses.fr/1997LYO1T238.

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46

Singaram, Vinod Krishnan. "The Role of Neuronal Leak Channels in Anesthesia." Case Western Reserve University School of Graduate Studies / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=case1339372305.

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47

Orliaguet, Gilles. "Effets diaphragmatiques des médicaments utilisés en anesthésie au cours du développement postnatal." Paris 6, 2002. http://www.theses.fr/2002PA066278.

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48

Kuhn, Mathias. "Vergleichende Untersuchung von Halothan und Isofluran während laparoskopischer Eingriffe beim Pferd." [S.l. : s.n.], 2003. http://dol.uni-leipzig.de/pub/2003-52.

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49

Schmucker, Nicola. "Duplexsonographische Untersuchung kopfversorgender Gefässe beim Pferd unter Halothan-Narkose in verschiedenen Lagerungen /." [S.l.] : [s.n.], 1997. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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50

Wenger, Sandra. "Die Kurznarkose zur Ferkelkastration mit Halothan : eine Feldstudie zur Überprüfung der Machbarkeit, des Aufwandes und der Kosten /." [S.l.] : [s.n.], 2001. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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