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Dissertations / Theses on the topic 'Haplotype diversity'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Rogers, Emma Jayne. "Haplotype evolution and human genetic diversity." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342507.

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2

Xu, Xiao. "Human alpha defensin CNV haplotype diversity." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/51262/.

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Humans have highly variable number of alpha defensin genes, with between 3-16 diploid copies. Alpha-defensin genes have important roles in human innate immunity and diseases. Recently, GWAS studies reported this locus associated with IgA nephropathy and periodontitis. However, the underlying mechanism of association is not clear. In this Ph.D. thesis, human alpha defensin CNV flanking haplotype diversity in global populations was studied and the association between diseases and haplotype classes was discussed. Then a novo method to detect variants from inside the DEFA1A3 CNV was developed and

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3

McGee, Kate. "Evolutionary Factors Shaping Haplotype and Nucleotide Diversity in Humans and Malaria." NCSU, 2008. http://www.lib.ncsu.edu/theses/available/etd-01102008-104027/.

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Cheaper and more rapid DNA sequencing has led to the accumulation of large amounts of genetic data and has fueled the development of new methods to analyze this data. Using population genetics theory and computational methods we can explore the evolutionary forces that shape genetic variation within and among populations of humans and malaria parasites. Demographic events such as population size change influence current patterns of genetic variation. Accounting for the demographic history of a population is critical in the interpretation of population genetic analyses, particularly in detectin

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4

Fletcher, Benjamin. "Haplotype diversity at the CYP2D6 locus : human demography, evolution and disease susceptibility." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404668.

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5

Dicks, Kara Leanne. "Unravelling major histocompatibility complex diversity in the Soay sheep of St Kilda." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31412.

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The major histocompatibility complex (MHC) is one of the most variable regions in the vertebrate genome. Many genes within the MHC play important roles in the development of an immune response, including the response to pathogens, by presenting pathogen fragments to T cells. Pathogen-mediated balancing selection is thought to be important in maintaining the high levels of allelic variation at these loci, though the precise mechanism remains unclear. The number of studies of MHC diversity in non-model organisms has increased dramatically in recent years as genotype data have become cheaper and

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6

Mwema, Hadija Saidi. "Forensic identification of six of Tanzanian populations using the extended haplotype markers." Thesis, University of the Western Cape, 2011. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_2349_1325671867.

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The aim of the present study was to evaluate the power of discrimination and genetic (diversity) parameters in the Y chromosome extended haploytpe markers in populations of Tanzania for forensic and populations studies. Eleven Y chromosome extended haplotype markers were selected for this study, these includes Minimal haplotypes markers i.e. DYS19, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS389I/II and two additional markers DYS438 and DYS439. Six populations of Tanzania were investigated under this study. These populations were selected based on the language family categories<br>Niger Cong

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7

Cantet, Mélissa. "Variation phénotypique de la résistance quantitative à Phytophthora capsici dans la diversité naturelle du piment, et diversité moléculaire et profil d'évolution du QTL majeur Pc5.1." Thesis, Montpellier, SupAgro, 2013. http://www.theses.fr/2013NSAM0006.

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L'utilisation de variétés présentant des résistances quantitatives polygéniques est une pratique respectueuse de l'environnement et potentiellement durable pour lutter contre les bioagresseurs. Les résistances quantitatives sont cependant mal connues et encore peu exploitées. Via l'étude de l'interaction Capsicum spp. / Phytophthora capsici, les objectifs sont de (i) caractériser la diversité naturelle de l'hôte pour le phénotype quantitatif de résistance, (ii) décrire la diversité au QTL Pc5.1, déterminant majeur de la résistance, conservé chez les géniteurs et efficace à large spectre, et (i

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8

Tano, Stina. "Seaweed in the tropical seascape : Importance, problems and potential." Doctoral thesis, Stockholms universitet, Institutionen för ekologi, miljö och botanik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-129256.

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The increasing demand for seaweed extracts has led to the introduction of non-native seaweeds for farming purposes in many tropical regions. Such intentional introductions can lead to spread of non-native seaweeds from farming areas, which can become established in and alter the dynamics of the recipient ecosystems. While tropical seaweeds are of great interest for aquaculture, and have received much attention as pests in the coral reef literature, little is known about the problems and potential of natural populations, or the role of natural seaweed beds in the tropical seascape. This thesis

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9

Perkins, Christopher J. "Ecology of Isolated Greater Sage-Grouse Populations Inhabiting the Wildcat Knolls and Horn Mountain, Southcentral Utah." DigitalCommons@USU, 2010. https://digitalcommons.usu.edu/etd/694.

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Greater sage-grouse (Centrocercus urophasianus) currently inhabit about 56% of pre-settlement distribution of potential habitat. In 2005, the Castle Country Adaptive Resources Management Local Working Group (CaCoARM) was formed to address concerns regarding local sage-grouse populations in Carbon and Emery counties. In 2006-2007, CaCoARM identified the Wildcat Knolls and Horn Mountain as areas of special concern for greater sage-grouse conservation. Both sites selected by the group were inhabited by what appeared to be small isolated sage-grouse populations. Factors limiting small isolated

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10

Cloete, Kevin Wesley. "Development of Y-STR genotyping systems suitable for sexual assault cases in South Africa." Thesis, University of the Western Cape, 2010. http://etd.uwc.ac.za/usrfiles/modules/etd/docs/etd_gen8Srv25Nme4_4315_1274816776.pdf.

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11

Cooper, Erin Elaine 1981. "Population biology and reproductive ecology of Chlorostoma (Tegula) funebralis, an intertidal gastropod." Thesis, University of Oregon, 2010. http://hdl.handle.net/1794/10916.

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xv, 99 p. : ill. (some col.) A print copy of this thesis is available through the UO Libraries. Search the library catalog for the location and call number.<br>The trochid gastropod Chlorostoma (Tegula) funebralis is found in rocky intertidal habitats along the west coast of North America from Baja California to Vancouver Island. Size-frequency distributions of populations were analyzed along a latitudinal gradient from northern Oregon to Baja California. Populations in California and southern Oregon were dominated by individuals in the juvenile size classes (0.1g-2g). Along the Oregon coast,

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12

Cantet, Mélissa. "Variation phénotypique de la résistance quantitative à Phytophthora capsici dans la diversité naturelle du piment, et diversité moléculaire et profil d'évolution du QTL majeur Pc5.1." Electronic Thesis or Diss., Montpellier, SupAgro, 2013. http://www.theses.fr/2013NSAM0006.

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L'utilisation de variétés présentant des résistances quantitatives polygéniques est une pratique respectueuse de l'environnement et potentiellement durable pour lutter contre les bioagresseurs. Les résistances quantitatives sont cependant mal connues et encore peu exploitées. Via l'étude de l'interaction Capsicum spp. / Phytophthora capsici, les objectifs sont de (i) caractériser la diversité naturelle de l'hôte pour le phénotype quantitatif de résistance, (ii) décrire la diversité au QTL Pc5.1, déterminant majeur de la résistance, conservé chez les géniteurs et efficace à large spectre, et (i

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13

Flores, Bello André 1992. "Population genetic landscape of Basques." Doctoral thesis, Universitat Pompeu Fabra, 2019. http://hdl.handle.net/10803/668156.

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Basque people have been the focus of many studies in the last decades due to cultural and genetic characteristics that place them as an outlier population within the European landscape. Despite the existence of large amount of studies, several controversies exist in the population genetics field: their highest frequencies of Rh-negative, a strong genetic differentiation, a genetic substructure, and their connections with the main ancient European groups along history. Most of the previous studies focused on Basques have suffered from methodological flowbacks and weak study designs. In this the

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14

Fowler, Elizabeth Victoria. "Genetic analysis of the koala (Phascolarctos cinerus)." Thesis, Queensland University of Technology, 1999.

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15

Mateu, Morante Eva. "Anàlisi de la variació genètica de les regions CFTR i GBA en poblacions humanes de tot el món." Doctoral thesis, Universitat Pompeu Fabra, 2001. http://hdl.handle.net/10803/7063.

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Aquest treball és una contribució als estudis de diversitat del genoma humà i pretén estudiar la variació genètica existent a nivell mundial en dos gens, causants de malaltia, el gen CFTR i el gen GBA, en cromosomes d'individus sans. Mutacions en aquests gens produeixen la fibrosi quística i la malaltia de Gaucher respectivament. La fibrosi quística és la malaltia autosòmica recessiva més comuna en poblacions europees. La malaltia de Gaucher és la malaltia lisosòmica d'acumulació lipídica més freqüent. L'estudi analitza la variació genètica en diferents polimorfismes d'ambdós gens; reconstruei

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16

Van, Dorp L. "Investigating processes driving genetic diversity in human populations using dense haplotypes." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1542974/.

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Although it is well established that DNA varies substantially among different world-wide human groups, the principal forces driving this genetic diversity are not well understood. This PhD thesis aims to describe genetic patterns among a wide range of human groups and characterize the primary historical, anthropological and sociological factors that contribute to observed levels of genetic diversity among these groups. In particular, through development and application of sophisticated haplotype-based techniques to several diverse human datasets, this work sheds light on the effects on genetic

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17

Koffi, Kouamé Guillaume. "Etude de la variabilité génétique et de la phylogéographie de Santiria trimera (Burseraceae): implications pour une conservation durable des forêts humides d'Afrique." Doctoral thesis, Universite Libre de Bruxelles, 2010. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210035.

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La phylogéographie intègre l’information géographique et génétique pour inférer l’histoire démographique et les processus évolutifs des espèces. La présente étude recherche à travers les patrons de différenciation de l’ADN chloroplastique (ADNcp) au sein de Santiria trimera (Oliv.) H.J.LAM ex AUBR. [Emend. ONANA] la reconstitution d’une histoire des végétations des écosystèmes de forêts tropicales humides d’Afrique. Le modèle S. trimera est un arbre dioïque endémique des forêts humides d’Afrique dont les drupes sont dispersées par les primates et les oiseaux. Les formes morphologiques de ce mo

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18

Alburaki, Mohamed. "Analyse de la diversité moléculaire et morphométrique des populations d'abeilles de Syrie Apis mellifera syriaca : application à la conservation et à la sélection des populations d'abeilles." Paris 6, 2011. http://www.theses.fr/2011PA066199.

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Pour étudier la diversité génétique et morphométrique des populations d'abeille syrienne Apis mellifera syriaca, nous avons réalisé un échantillonnage de 1800 colonies d'abeilles couvrant trois pays différents: la Syrie, le Liban et l'Irak. Une abeille par colonie a été échantillonnée et conservée individuellement dans de l'alcool absolu. Ces abeilles ont été disséquées et les ailes conservées pour d'éventuelles analyses morphométriques. L'extraction des ADN totaux a été effectuée sur les thorax de ces abeilles. Chaque échantillon a ensuite été analysé pour deux marqueurs moléculaires: i) l'AD

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19

Holden, Anne Duval. "Sahara passage : the post-glacial re-colonisation of North Africa by mitochondrial L haplotypes and its role in North African genetic diversity." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611420.

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20

Takenaka, Shotaro. "Genetic diversity and evolutionary relationships of emmer wheat and its related species based on novel haplotypes of Ppd-1 (photoperiod response) genes and their surrounding DNA sequences." Kyoto University, 2013. http://hdl.handle.net/2433/175040.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第17611号<br>農博第1973号<br>新制||農||1008(附属図書館)<br>学位論文||H25||N4732(農学部図書室)<br>30377<br>京都大学大学院農学研究科応用生物科学専攻<br>(主査)准教授河原太八, 教授遠藤隆, 教授奥野哲郎<br>学位規則第4条第1項該当

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21

Ba, Alhassane. "Hétérogénéité génétique des groupes sanguins au Mali : impact transfusionnel." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM5048/document.

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Les antigènes de groupes sanguins érythrocytaires peuvent être responsables d’une allo-immunisation anti-érythrocytaire et d’accidents immuno-hémolytiques lors de transfusion ou de grossesse. La transfusion des populations d’Afrique sub-saharienne est complexifiée par l’absence d’expression d’antigènes publics, l’expression d’antigènes privés et l’expression d’antigènes partiels en particulier pour le système RH. L’étude des systèmes de groupes sanguins d’intérêt transfusionnel chez les donneurs de Bamako a confirmé l’efficacité de la stratégie du génotypage multiplex incluant des polymorphism

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22

Alencar, Figueiredo Lucio Flavio. "Analyse fonctionnelle de la diversité agronomique chez le sorgho (Sorghum bicolor ssp. Bicolor) : analyse de la diversité des séquences et de la variabilité au niveau de gènes clés pour la qualité du grain." Montpellier 2, 2007. http://www.theses.fr/2007MON20253.

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23

Davila-Flores, Amanda. "Host Plant Influences on Performance and Haplotype Diversity of Dalbulus maidis, a Specialist Herbivore of Zea." Thesis, 2012. http://hdl.handle.net/1969.1/148396.

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In one study, a suite of plants from the maize genus Zea L. (Poaceae) and the specialist herbivore Dalbulus maidis (DeLong and Wolcott, 1923) (Hemiptera: Cicadellidae) were used to test the hypotheses that anti-herbivore defenses are affected by plant life-history evolution and human intervention through domestication and breeding for high yield. The suite of Zea host plants included one Mexican commercial hybrid maize Zea mays ssp. mays L., a landrace variety of maize, two populations of Balsas teosinte (Zea mays ssp. parviglumis Iltis & Doebley), and perennial teosinte (Z. diploperennis Ilti

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24

Saidi, Mwema Hadija. "Forensic identification of six of Tanzanian populations using the extended haplotype markers." Thesis, 2011. http://hdl.handle.net/11394/3571.

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The aim of the present study was to evaluate the power of discrimination and genetic(diversity) parameters in the Y chromosome extended haploytpe markers in populations of Tanzania for forensic and populations studies. Eleven Y chromosome extended haplotype markers were selected for this study, these includes Minimal haplotypes markers i.e. DYS19, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS389I/II and two additional markers DYS438 and DYS439. Six populations of Tanzania were investigated under this study. These populations were selected based on the language family categories; Niger Congo (

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