Academic literature on the topic 'Hard gelatin capsules'

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Journal articles on the topic "Hard gelatin capsules"

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Sonar, Shivani, Sheetal Gondkar, and Ravindranath B. Saudagar. "Liquid Filled Hard Gelatin Capsule." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 832–35. http://dx.doi.org/10.22270/jddt.v9i3-s.2794.

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Novel dosage forms emerges more and more in recent years. One of them is liquid-filled hard gelatin capsules, which have gelatin or the hydroxypropyl methyl cellulose (HPMC) as capsule shell. The liquid-filled hard gelatin capsule is gradually getting attention because of its new-concept dosage form design, which bring liquid drugs by solid form. The paper mostly presents application, pharmaceutical manufacturing, quality assessment, vision of liquid-filled hard gelatin capsules and emphases on the application and pharmaceutical manufacturing of liquid-filled capsule. It is recommended that th
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Nurilmala, Mala, Noviyan Darmawan, Erin Apriliani Wulandari Putri, Agoes M. Jacoeb, and Tun Tedja Irawadi. "Pangasius Fish Skin and Swim Bladder as Gelatin Sources for Hard Capsule Material." International Journal of Biomaterials 2021 (August 27, 2021): 1–6. http://dx.doi.org/10.1155/2021/6658002.

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In this paper, we report the extraction and characterization of gelatin from the abundant industrial fishery waste of Pangasius skin and swim bladder and its application as the base material for hard capsule shells. The yield of gelatin ranged between 19 and 23%, content of moisture is 7.6–9.2%, ash is 1.1–1.7%, pH is 4.1–5.2, gel strength is 238–278 bloom, and viscosity is 65–74.7% mP. SDS-PAGE showed all gelatins have chains of α1, α2, and β-peptides. The skin, swim bladder, and mixed gelatins were successfully used in the production of hard capsule shells. The dimensions, weight, disintegra
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Zilhadia, Zilhadia, Yahdiana Harahap, Irwandi Jaswir, and Effionora Anwar. "Evaluation and Characterization of Hard-Shell Capsules Formulated by Using Goatskin Gelatin." Polymers 14, no. 20 (2022): 4416. http://dx.doi.org/10.3390/polym14204416.

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Gelatin is used as an additive in medicine, food, and cosmetics. Gelatin from goatskin is a new excipient that has not been explored by researchers, including for hard-shell capsules. The aim of this study was to evaluate and characterize the hard-shell capsules produced from goatskin gelatin. The goatskin gelatin was extracted by an acid hydrolysis method, and the functional properties were investigated. Hard-shell capsules were then produced from goatskin gelatin, evaluated, and characterized. The gelatin extracted from goatskin had 56.9% ± 0.95 clarity and a pH of 5.11 ± 0.09, 97.51% ± 1.1
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Ramli, Nur Amalina, Nurul Natasya Amira Kamaluddin, and Fatmawati Adam. "Mechanical, Structural and Physical Properties of Carrageenan-Gum Arabic Biocomposite Film for Hard Capsule Application." Solid State Phenomena 340 (December 23, 2022): 11–18. http://dx.doi.org/10.4028/p-c2wejl.

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The hard capsule market growth is mainly driven by the demand for gelatin capsules made of animals. Plant-based hard capsules, such as hydroxypropyl methylcellulose are currently in high demand for drug delivery, but the manufacturing process is costly with limited reagent supply. As an alternative, carrageenan from seaweed was used as a film-forming agent in this work. Carrageenan film possesses low mechanical strength, thus gum Arabic is incorporated to strengthen the biocomposite film. The films and hard capsules were produced with different concentrations of gum Arabic, ranging from 0 to 2
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Kaur, Darshan. "FORMULATION AND EVALUATION OF HARD GELATIN CAPSULES CONTAINING Bacopa Monnieri." INTERNATIONAL JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH (IJPER) 1, no. 02 (2020): 33–37. http://dx.doi.org/10.37021/ijper.v1i2.2.

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Introduction: The present work deals the formulation of hard gelatin capsules containing granules of Brahmi (Bacopa monnieri). Bacopa monnieri is used in Ayurvedic traditional medicine to improve memory and to treat various ailments. The aim of the project is to achieve immediate release of drug from dosage form to achieve therapeutic efficacy and patient compliance. Hard gelatin capsules offer rapid drug release and protection from atmospheric oxygen. Materials and methods: In this work we have prepared the granules of Brahmi and filled into the empty hard gelatin capsule shells. The hard gel
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Al-Tabakha, Moawia M. "HPMC Capsules: Current Status and Future Prospects." Journal of Pharmacy & Pharmaceutical Sciences 13, no. 3 (2010): 428. http://dx.doi.org/10.18433/j3k881.

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Hydroxypropyl methylcellulose (HPMC) is employed for a wide variety of pharmaceutical and food preparations. Its applications as viscolizing agent (thickening agent), coating polymer, bioadhesive, in solid dispersion to enhance solubility, binder in the process of granulation and in modified release formulations have been well documented. One other notable use is in the production of capsule shells, replacing the animal derived gelatin in conventional two-piece capsules. The aim of this review is to systemically survey published literature on the HPMC use in capsule shells and resolve question
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Uchimura, Érica Mayumi Takase, Irene Harumi Kamata Barcelos, Deborah Brandão de Paiva, Lucia Figueiredo Mourão, and Agricio Nubiato Crespo. "Evaluation of the location of capsules swallowed with food during the pharyngeal phase triggering in asymptomatic adults." CoDAS 26, no. 6 (2014): 476–80. http://dx.doi.org/10.1590/2317-1782/20140000045.

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OBJECTIVE: To assess the location of hard gelatin capsules in the pharyngeal phase triggering among asymptomatic adults. INTRODUCTION: The location of the bolus during the pharyngeal phase triggering provides information about the sensorimotor model of the beginning of deglutition onset. PURPOSE: To evaluate the location of hard gelatin capsules in the pharyngeal phase triggering among asymptomatic adults. METHODS: A videofluoroscopy swallowing study was carried out in 60 subjects (14 male and 46 female participants) aged between 27 and 55 years, who were evaluated with hard gelatin capsules #
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Controulis, John, and Parke Davis. "Hard Gelatin Capsules – New Developments from Capsugel." Drug Development and Industrial Pharmacy 11, no. 2-3 (1985): 585–90. http://dx.doi.org/10.3109/03639048509056889.

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GARG, RAM, SARFARAZ ALAM, and VANDANA SHARMA. "A Review on Gelatin Production and a Special Type of Hard Gelatin Capsules With Their Packaging and Storage." Indian Journal of Health Care, Medical & Pharmacy Practice 4, no. 2 (2023): 71–78. http://dx.doi.org/10.59551/ijhmp/25832069/2023.4.2.60.

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In this review it is explained about production of gelatin and a special type of hard gelatin capsules with their packaging and storage. Capsules are solid dosage preparations that contain a soft soluble shell of gelatin that encloses the drug substance(s) and/or excipients whereas hard capsules are made up of two pieces that resemble cylinders that are closed at one end: the longer piece is called the "body," and the shorter piece is called the "cap." A variety of formulation types, the majority of which are meant for oral administration, can be filled into capsules. Special applications incl
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Majee, Sutapa Biswas, Dhruti Avlani, and Gopa Roy Biswas. "HPMC AS CAPSULE SHELL MATERIAL: PHYSICOCHEMICAL, PHARMACEUTICAL AND BIOPHARMACEUTICAL PROPERTIES." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 10 (2017): 1. http://dx.doi.org/10.22159/ijpps.2017v9i10.20707.

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The most common instability problem of gelatin capsules arises from negative impact of extremes of temperature and especially atmospheric relative humidity on the mechanical integrity of the capsule shells with adverse effect extended even to the fill material. Moreover, choice of fill materials is highly restricted either due to their specific chemical structure, physical state or hygroscopicity. Additional reports of unpredictable disintegration and dissolution of filled hard gelatin capsules in experimental studies have prompted the search for a better alternative capsule shell material. Th
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Dissertations / Theses on the topic "Hard gelatin capsules"

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Chatham, Sarah Marianna. "Characterisation of molten filled hard gelatin capsules." Thesis, King's College London (University of London), 1985. https://kclpure.kcl.ac.uk/portal/en/theses/characterisation-of-molten-filled-hard-gelatin-capsules(5b2e73bf-b02c-4ecc-b00a-146fd90ec814).html.

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Tan, Soo Bin. "Filling of hard gelatin capsules with powders of different flow properties." Thesis, University College London (University of London), 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.252001.

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Dordunoo, Stephen Kwaku. "Characterization of drug-carrier systems for liquid filling of hard gelatin capsules." Thesis, Liverpool John Moores University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261411.

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Veski, Peep. "Use of hard gelatin capsules and sodium alginates in peroral prolonged-release formulations /." Helsinki, 1994. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=006530628&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Saeed, Tariq. "Rheological characterization of poloxamer/silicon dioxide gels for liquid filled hard gelatin capsules." Thesis, University of Sunderland, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312083.

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Guterres, Silvia Stanisçuaski. "Influência de adjuvantes sobre as características farmacêuticas de cápsulas de gelatina dura contendo hidroclorotiazida." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 1990. http://hdl.handle.net/10183/144071.

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A biodisponibilidade é uma característica decisiva para a eficácia dos medicamentos, podendo sua intensidade ser estimada através da cedência "in vitro". Vários fatores são capazes de influenciá-la, entre eles a composição quali e quantitativa dos adjuvantes, assim como as características da substância ativa e da forma farmacêutica. A hidroclorotiazida é um diurético de amplo emprego, que apresenta problemas de biodisponibilidade e bioequivalência devido a sua baixa hidrossolubilidade. Através de planejamento fatorial 2 3 foram preparadas formulações de cápsulas de gelatina dura contendo 50 mg
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Marx, Amor. "To investigate the effect of a change in hard gelatin capsule supplier on a phenytoin sodium capsule formulation." Thesis, Port Elizabeth Technikon, 2004. http://hdl.handle.net/10948/265.

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Stability studies were undertaken at ambient (25ºC/60%RH) and accelerated conditions (40ºC/75%RH) to determine the effect of changing of hard gelatin capsule supplier on a phenytoin sodium (100 mg) capsule formulation. Three hard gelatin capsule suppliers: RP Scherer (Supplier A), Capsugel (supplier B) and Associated Caps (Supplier C) were used in the study. Capsules were analyzed just after filling of the capsules (T0), after 1 month (T1), after 2 months (T2) and after 3 months (T3) after being stored in securitainers under the above-mentioned conditions. The moisture content of the empty she
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Walters, Philippa Anne. "A rheological approach to the formulation and drug release of thixotropic gels for hard gelatin capsules." Thesis, University of Sunderland, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239687.

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Utting, Anita A. "Liquid filled hard gelatin capsules : an investigation of thermosoftened drug/poloxamer solid dispersion formulations in relation to drug release mechanisms." Thesis, University of Sunderland, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327315.

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Takase, Erica Mayumi 1985. "Avaliação da deglutição de alimentos e cápsulas gelatinosas duras em adultos assintomáticos = Evaluation of swallowing food and hard gelatin capsules in asymptomatic adults." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/313719.

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Orientador: Agricio Nubiato Crespo<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-22T21:10:45Z (GMT). No. of bitstreams: 1 Takase_EricaMayumi_M.pdf: 1010847 bytes, checksum: 5c86c3afa9fc26a724e923475e8907ec (MD5) Previous issue date: 2013<br>Resumo: As medidas de duração e a localização do bolo no disparo da fase faríngea são significantes no estudo da deglutição. Objetivo: avaliar a interferência de a consistência alimentar e da idade do sujeito na duração das fases oral, de transição e faríngea na deglutiç
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Book chapters on the topic "Hard gelatin capsules"

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M. Ofner Iii, Clyde, and Bill Bowman. "Hard Gelatin Capsules." In Protein-Based Films and Coatings. CRC Press, 2002. http://dx.doi.org/10.1201/9781420031980.ch15.

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Saha, Gourab. "Capsules." In A Text Book of Pharmaceutics for I Year Diploma in Pharmacy. THINKPLUS PHARMA PUBLICATIONS, 2024. http://dx.doi.org/10.69613/ghtjh139.

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Capsules are versatile solid dosage forms that offer unique advantages in drug delivery and patient acceptance. This section covers both hard and soft gelatin capsules, exploring their composition, manufacturing processes, and applications. The properties of gelatin and alternative shell materials, including vegetable-based and hydroxypropyl methylcellulose (HPMC) capsules, are discussed in relation to their impact on drug stability and release. Capsule filling processes for powders, granules, pellets, and liquids are examined, including manual, semi-automatic, and fully automatic filling meth
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Bukhari, Mr Syed Basharat, and Mr Jonny Kumar. "TABLETS AND CAPSULES IN PHARMACEUTICAL DOSAGE FORMS." In PRELIMINARY PHARMACEUTICS. KAAV PUBLICATIONS, 2023. http://dx.doi.org/10.52458/9788196830045.2023.eb.ch-13.

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Tablets and capsules, fundamental pharmaceutical dosage forms, are explored in this chapter, encompassing uncoated and coated tablets, modified release tablets, and hard and soft gelatin capsules. Tablets, solid and precise in dosing, come in uncoated and coated variations, each with distinct advantages and disadvantages. Modified release tablets offer diverse drug release patterns. Capsules, with versatile types such as hard gelatin, soft gelatin, vegetarian, and enteric-coated, provide advantages like ease of swallowing and taste masking. This chapter delves into their definitions, manufactu
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Kosasih, Kosasih, and Fitri Weningtyas. "Release Profiles of Natural Antioxidant Microcapsules from Hard Gelatin Capsules." In Pharmaceutical Science: New Insights and Developments Vol. 2. BP International, 2025. https://doi.org/10.9734/bpi/psnid/v2/4174.

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"Liquid-Filled and -Sealed Hard Gelatin Capsule Technologies." In Modified-Release Drug Delivery Technology. CRC Press, 2002. http://dx.doi.org/10.1201/9780203910337-17.

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Cole, Ewart. "Liquid-Filled and -Sealed Hard Gelatin Capsule Technologies." In Drugs and the Pharmaceutical Sciences. Informa Healthcare, 2002. http://dx.doi.org/10.1201/9780203910337.ch14.

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Conference papers on the topic "Hard gelatin capsules"

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Putri, Renny Primasari Gustia, Maya Soraya, Hendrawan Laksono, et al. "Comparison of free fatty acid value and peroxide value of shark liver oil in carrageenan hard capsules and gelatin soft capsules." In INTERNATIONAL CONFERENCE ON ORGANIC AND APPLIED CHEMISTRY (ICOAC) 2022. AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0184032.

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Poeloengasih, Crescentiana Dewi, Yudi Pranoto, Frida Dwi Anggraheni, and Djagal Wiseso Marseno. "Potential of sago starch/carrageenan mixture as gelatin alternative for hard capsule material." In PROCEEDINGS FROM THE 14TH INTERNATIONAL SYMPOSIUM ON THERAPEUTIC ULTRASOUND. Author(s), 2017. http://dx.doi.org/10.1063/1.4978108.

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