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Journal articles on the topic 'Hauschka'

Author: Grafiati

Published: 4 June 2021

Last updated: 8 February 2022

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1

Bertram, Mathias, Thomas Ostermann, and Peter F. Matthiessen. "Erforschung der Rhythmischen Einreibungen nach Wegman/Hauschka – eine Strukturphänomenologische Untersuchung." Pflege 18, no. 4 (August 1, 2005): 227–35. http://dx.doi.org/10.1024/1012-5302.18.4.227.

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Einleitung: Die in den 1990er Jahren begonnene Forschung über die Rhythmischen Einreibungen nach Wegman/Hauschka (RE) ist ein wesentlicher pflegewissenschaftlicher Beitrag zur Anerkennung komplementärer Verfahren der Pflege. Ziel, Material und Methoden: Auf der methodischen Basis einer durch Goethes Forschungsart inspirierten Leibphänomenologie wurde die Fragestellung untersucht: Was sind typische psychosomatische Reaktionsweisen von PatientInnen auf eine RE? Die durch theoretisches Sampling ermittelte Stichprobe bestand aus 13 PflegeexpertInnen für RE. Ergebnisse: Es wurden drei typische Reaktionsmuster gefunden: Lösen, Wiedereinssein und Neuvermögen. Diese Muster beschränken sich nicht auf Veränderungen körperlicher Parameter, sondern indizieren neben der physiologisch-vegetativen auch eine seelisch-geistige Dimension. Schlussfolgerung: Eine vorsichtige Interpretation der Ergebnisse kann den Schluss nahelegen, dass die hier generierten Konzepte als Archetypen menschlicher Reaktionen auf bestimmte Formen von therapeutischer Berührung verstanden werden können.

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2

Azawi, Shaymaa, Thomas Liehr, Martina Rincic, and Mattia Manferrari. "Molecular Cytogenomic Characterization of the Murine Breast Cancer Cell Lines C-127I, EMT6/P and TA3 Hauschka." International Journal of Molecular Sciences 21, no. 13 (July 1, 2020): 4716. http://dx.doi.org/10.3390/ijms21134716.

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Background: To test and introduce effective and less toxic breast cancer (BC) treatment strategies, animal models, including murine BC cell lines, are considered as perfect platforms. Strikingly, the knowledge on the genetic background of applied BC cell lines is often sparse though urgently necessary for their targeted and really justified application. Methods: In this study, we performed the first molecular cytogenetic characterization for three murine BC cell lines C-127I, EMT6/P and TA3 Hauschka. Besides fluorescence in situ hybridization-banding, array comparative genomic hybridization was also applied. Thus, overall, an in silico translation for the detected imbalances and chromosomal break events in the murine cell lines to the corresponding homologous imbalances in humans could be provided. The latter enabled a comparison of the murine cell line with human BC cytogenomics. Results: All three BC cell lines showed a rearranged karyotype at different stages of complexity, which can be interpreted carefully as reflectance of more or less advanced tumor stages. Conclusions: Accordingly, the C-127I cell line would represent the late stage BC while the cell lines EMT6/P and TA3 Hauschka would be models for the premalignant or early BC stage and an early or benign BC, respectively. With this cytogenomic information provided, these cell lines now can be applied really adequately in future research studies.

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3

Nicolls, Sarah. "‘New Blood’: 130701, 15th Anniversary Showcase, Brighton Festival." Tempo 70, no. 278 (September 28, 2016): 88–89. http://dx.doi.org/10.1017/s0040298216000425.

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The Spire, St Mark's chapel, is an artist-led creation space in Brighton. Normally it's a blank space without heating or equipment but for the night of 10 May it is fantastically dressed up with lights, pictures and a projection saying ‘landmark post-classical recordings’. This is a label showcase for 130701, an offshoot of FatCat Records set up by Dave Howell in 2001. Hauschka, one of the label's longstanding artists who has opened up his imaginative and playful inside-piano playing to commercial audiences, and the label's willingness to support live experimental music are the reasons I'm here.

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4

Kierey, Beate. "Zur Wirkungskraft und Anwendung der Rhythmischen Einreibungen nach Wegman/Hauschka in der ambulanten Pflege." Schweizerische Zeitschrift für Ganzheitsmedizin / Swiss Journal of Integrative Medicine 28, no. 6 (2016): 333–35. http://dx.doi.org/10.1159/000452847.

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5

Santesmases, María Jesús. "Human Chromosomes and Cancer." Historical Studies in the Natural Sciences 45, no. 1 (2014): 85–114. http://dx.doi.org/10.1525/hsns.2015.45.1.85.

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In this paper I analyze the trajectory of research objects and experiments on tumor cells that led the Swedish geneticist, Albert Levan, through successive collaborations with Theodore Hauschka in Philadelphia (U.S.) and Joe Hin Tjio in Lund (Sweden), from plants to mice and from mice to human chromosomes. Tumor chromosomes were created and recreated in mice bodies by Eva Klein and Georg Klein as ascites—fluid—tumors, whereas human tumors were transplanted from the bodies of cancer patients into mice by Helene W. Toolan. The cultures of cytogenetics and microscopic observation were therefore opened up, from agricultural and botanical research to the clinical laboratory. I suggest it was research on tumors and cancer cells that led to a method for obtaining clear slides, thereby providing evidence of the new number of forty-six human chromosomes, as presented by Tjio and Levan in 1956. Along this research trajectory, the knowledge and practices of cytogenetics were medicalized—a medicalization that situated both cancer research and cytogenetics at the origins of biomedicine.

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6

Clegg, C. H., and S. D. Hauschka. "Heterokaryon analysis of muscle differentiation: regulation of the postmitotic state." Journal of Cell Biology 105, no. 2 (August 1, 1987): 937–47. http://dx.doi.org/10.1083/jcb.105.2.937.

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MM14 mouse myoblasts withdraw irreversibly from the cell cycle and become postmitotic within a few hours of being deprived of fibroblast growth factor (Clegg, C. H., T. A. Linkhart, B. B. Olwin, and S. D. Hauschka, 1987, J. Cell Biol., 105:949-956). To examine the mechanisms that may regulate this developmental state of skeletal muscle, we tested the mitogen responsiveness of various cell types after their polyethylene glycol-mediated fusion with post-mitotic myocytes. Heterokaryons containing myocytes and quiescent nonmyogenic cells such as 3T3, L cell, and a differentiation-defective myoblast line (DD-1) responded to mitogen-rich medium by initiating DNA synthesis. Myonuclei replicated DNA and reexpressed thymidine kinase. In contrast, (myocyte x G1 myoblast) heterokaryons failed to replicate DNA in mitogen-rich medium and became postmitotic. This included cells with a nuclear ratio of three myoblasts to one myocyte. Proliferation dominance in (myocyte x 3T3 cell) and (myocyte x DD-1) heterokaryons was conditionally regulated by the timing of mitogen treatment; such cells became postmitotic when mitogen exposure was delayed for as little as 6 h after cell fusion. In addition, (myocyte x DD-1) heterokaryons expressed a muscle-specific trait and lost epidermal growth factor receptors when they became postmitotic. These results demonstrate that DNA synthesis is not irreversibly blocked in skeletal muscle; myonuclei readily express proliferation-related functions when provided with a mitogenic signal. Rather, myocyte-specific repression of DNA synthesis in heterokaryons argues that the postmitotic state of skeletal muscle is regulated by diffusible factors that inhibit processes of cellular mitogenesis.

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7

Parker, Gretchen E., Bartholomew A. Pederson, Mariko Obayashi, Jill M. Schroeder, Robert A. Harris, and Peter J. Roach. "Gene expression profiling of mice with genetically modified muscle glycogen content." Biochemical Journal 395, no. 1 (March 15, 2006): 137–45. http://dx.doi.org/10.1042/bj20051456.

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Glycogen, a branched polymer of glucose, forms an energy re-serve in numerous organisms. In mammals, the two largest glyco-gen stores are in skeletal muscle and liver, which express tissue-specific glycogen synthase isoforms. MGSKO mice, in which mGys1 (mouse glycogen synthase) is disrupted, are devoid of muscle glycogen [Pederson, Chen, Schroeder, Shou, DePaoli-Roach and Roach (2004) Mol. Cell. Biol. 24, 7179–7187]. The GSL30 mouse line hyper-accumulates glycogen in muscle [Manchester, Skurat, Roach, Hauschka and Lawrence (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 10707–10711]. We performed a microarray analysis of mRNA from the anterior tibialis, medial gastrocnemius and liver of MGSKO mice, and from the gastroc-nemius of GSL30 mice. In MGSKO mice, transcripts of 79 genes varied in their expression in the same direction in both the anterior tibialis and gastrocnemius. These included several genes encoding proteins proximally involved in glycogen metabolism. The Ppp1r1a [protein phosphatase 1 regulatory (inhibitor) sub-unit 1A] gene underwent the greatest amount of downregulation. In muscle, the downregulation of Pfkfb1 and Pfkfb3, encoding isoforms of 6-phosphofructo-2-kinase/fructose-2,6-bisphospha-tase, is consistent with decreased glycolysis. Pathways for branched-chain amino acid, and ketone body utilization appear to be downregulated, as is the capacity to form the gluconeogenic precursors alanine, lactate and glutamine. Expression changes among several members of the Wnt signalling pathway were identified, suggesting an as yet unexplained role in glycogen meta-bolism. In liver, the upregulation of Pfkfb1 and Pfkfb3 expression is consistent with increased glycolysis, perhaps as an adaptation to altered muscle metabolism. By comparing changes in muscle expression between MGSKO and GSL30 mice, we found a subset of 44 genes, the expression of which varied as a function of muscle glycogen content. These genes are candidates for regulation by glycogen levels. Particularly interesting is the observation that 11 of these genes encode cardiac or slow-twitch isoforms of muscle contractile proteins, and are upregulated in muscle that has a greater oxidative capacity in MGSKO mice.

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8

Olwin, B. B., and S. D. Hauschka. "Cell surface fibroblast growth factor and epidermal growth factor receptors are permanently lost during skeletal muscle terminal differentiation in culture." Journal of Cell Biology 107, no. 2 (August 1, 1988): 761–69. http://dx.doi.org/10.1083/jcb.107.2.761.

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One characteristic of skeletal muscle differentiation is the conversion of proliferating cells to a population that is irreversibly postmitotic. This developmental change can be induced in vitro by depriving the cultures of specific mitogens such as fibroblast growth factor (FGF). Analysis of cell surface FGF receptor (FGFR) in several adult mouse muscle cell lines and epidermal growth factor receptor (EGFR) in mouse MM14 cells reveals a correlation between receptor loss and the acquisition of a postmitotic phenotype. Quiescent MM14 cells, mitogen-depleted, differentiation-defective MM14 cells, and differentiated BC3H1 muscle cells (a line that fails to become postmitotic upon differentiation) retained their cell surface FGFR. These results indicate that FGFR loss is not associated with either reversible cessation of muscle cell proliferation or biochemical differentiation and thus, further support a correlation between receptor loss and acquisition of a postmitotic phenotype. Comparison of the kinetics for growth factor receptor loss and for commitment of MM14 cells to a postmitotic phenotype reveals that FGFR rises transiently from approximately 700 receptors/cell to a maximum of approximately 2,000 receptors/cell 12 h after FGF removal, when at the same time, greater than 95% of the cells are postmitotic. FGFR levels then decline to undetectable levels by 24 h after FGF removal. During the interval in which FGFR increases and then disappears there is no change in its affinity for FGF. The transient increase in growth factor receptors appears to be due to a decrease in ligand-mediated internalization because EGFR, which undergoes an immediate decline when cultures are deprived of FGF (Lim, R. W., and S. D. Hauschka. 1984. J. Cell Biol. 98:739-747), exhibits a similar transient rise when cultures are grown in media containing both EGF and FGF before switching the cells to media without these added factors. These results indicate that the loss of certain growth factor receptors is a specific phenotype acquired during skeletal muscle differentiation, but they do not resolve whether regulation of FGFR number is causal for initiation of the postmitotic phenotype. A general model is presented in the discussion.

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9

Mathew, Thomas. "Bioequivalence Studies in Drug Development: Methods and Applications by Dieter Hauschke, Volker Steinijans, Iris Pigeot." International Statistical Review 75, no. 2 (August 2007): 272–73. http://dx.doi.org/10.1111/j.1751-5823.2007.00015_24.x.

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10

Chow, Shein-Chung. "Bioequivalence Studies in Drug Development, Methods and Applications by D. HAUSCHKE, V. STEINIJANS, and I. PIGEOT." Biometrics 63, no. 3 (August 31, 2007): 969–70. http://dx.doi.org/10.1111/j.1541-0420.2007.00856_4.x.

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11

Patterson, Scott. "A Review of: “Bioequivalence Studies in Drug Development: Methods and Applications, by D. Hauschke, V. Steinijans and I. Pigeot”." Journal of Biopharmaceutical Statistics 18, no. 1 (December 10, 2007): 208–9. http://dx.doi.org/10.1080/10543400701668357.

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12

Ghaderi, A., L. Leda, M. Schobben, D. Korn, and A. R. Ashouri. "High-resolution stratigraphy of the Changhsingian (Late Permian) successions of NW Iran and the Transcaucasus based on lithological features, conodonts and ammonoids." Fossil Record 17, no. 1 (March 7, 2014): 41–57. http://dx.doi.org/10.5194/fr-17-41-2014.

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Abstract. The Permian–Triassic boundary sections in north-western Iran belong to the most complete successions, in which the largest mass extinction event in the history of the Earth can be studied. We investigated the Changhsingian stage in six sections in the area of Julfa (Aras Valley) for their lithology, conodonts and ammonoids. Revision of the biostratigraphy led to the separation of 10 conodont zones (from bottom to top Clarkina orientalis–C. subcarinata interval zone, C. subcarinata, C. changxingensis, C. bachmanni, C. nodosa, C. yini, C. abadehensis, C. hauschkei, Hindeodus praeparvus–H. changxingensis and Merrilina ultima–Stepanovites ?mostleri zones) and 8 ammonoid zones (from bottom to top Iranites transcaucasius–Phisonites triangulus, Dzhulfites nodosus, Shevyrevites shevyrevi, Paratirolites trapezoidalis, P. waageni, Stoyanowites dieneri, Abichites stoyanowi and Arasella minuta zones). The new ammonoid genera Stoyanowites and Arasella are described.

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13

Julious, Stevens. "Bioequivalence studies in drug development methods and applications Hauschke D, Steinijans V, Pigeot I (2007) Wiley, Chichester, England, www.wiley.com; $110.00, £61.95." Pharmaceutical Statistics 11, no. 2 (April 20, 2011): 191. http://dx.doi.org/10.1002/pst.488.

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14

Munzel, Ullrich. "Bioequivalence Studies in Drug Development. D. Hauschke, V. Steinijans, I. Pigeot (2007). New York, Wiley. ISBN 978-0-470-0975-4." Biometrical Journal 51, no. 2 (April 2009): 375–76. http://dx.doi.org/10.1002/bimj.200800204.

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15

Newlands, Amy. "Book review: Hauschke D, Steinijans V and Pigeot I 2007: Bioequivalence studies in drug development methods and application. Chichester: John Wiley & Sons Ltd. 311 p. ISBN 978-0-470-09475-4." Statistical Methods in Medical Research 18, no. 1 (February 2009): 112–13. http://dx.doi.org/10.1177/09622802090180010802.

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16

INNOCENTE, NADIA, and GERARDO PALLA. "Occurrence of D-amino acids in a typical semi-hard cheese." Journal of Dairy Research 66, no. 4 (November 1999): 633–37. http://dx.doi.org/10.1017/s0022029999003829.

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D-alanine (D-Ala), D-aspartic acid (D-Asp) and D-glutamic acid (D-Glu) are important constituents of the cell walls of bacteria responsible for fermentation processes, and have been detected in several fermented foods, such as cheeses, yogurt and vinegar (Palla et al. 1989; Brückner & Hausch, 1990; Dossena et al. 1991; Brückner et al. 1992; Gandolfi et al. 1992). In particular, D-amino acids have been found, free and abundant, in cheeses requiring long ripening periods (1–2 years; Santaguida et al. 1995). Their presence in cheeses could be related mainly to lysis of the bacterial wall, to which short-chain D-amino acids are bound, but also to the activity of bacterial racemases (Adams, 1972), which convert free L-amino acids generated during proteolysis. The content of these D-amino acids and the D:L ratio have been recently proposed as indicators of ripening and for quality assessment of Parmigiano Reggiano and Grana Padano cheeses (Marchelli et al. 1997).The aim of the present study was to determine D-amino acids in cheeses with shorter ripening periods to evaluate whether they could be useful as indicators of ripening and for quality assessment. The work was carried out with Montasio, a typical cheese produced in north-east Italy using traditional methods. Montasio is a semi-hard cheese produced from unpasteurized milk, cooked at 44–46 °C and consumed after at least 2 months ripening. This study represents an extension of previous work on free amino acid contents and ripening in semi-hard cheeses (Innocente, 1997).

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17

"Erforschung der Rhythmischen Einreibungen nach Wegman/Hauschka – ein lebenswissenschaftliches Problem." Der Merkurstab, 2004. http://dx.doi.org/10.14271/dms-18511-de.

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18

"Rudolf Hauschka - zur Wiederkehr seines 100. Geburtstages am 6. November 1991." Der Merkurstab, 1992. http://dx.doi.org/10.14271/dms-16029-de.

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19

"Zur Maltherapie. Ita Wegmans Zusammenarbeit mit Margarethe Hauschka und Liane Collot d'Herbois." Der Merkurstab, 1990. http://dx.doi.org/10.14271/dms-15682-de.

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20

""Studieren Sie den Rhythmus. Rhythmus trägt Leben." - Das Gespräch Steiner/Hauschka im Kontext der Arnheimer Vorträge 1924." Der Merkurstab, 2008. http://dx.doi.org/10.14271/dms-19256-de.

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21

"Erratum for the Research Article: “Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy” by L. Amoasii, C. Long, H. Li, A. A. Mireault, J. M. Shelton, E. Sanchez-Ortiz, J. R. McAnally, S. Bhattacharyya, F. Schmidt, D. Grimm, S. D. Hauschka, R. Bassel-Duby, E. N. Olson." Science Translational Medicine 10, no. 425 (January 24, 2018): eaat0240. http://dx.doi.org/10.1126/scitranslmed.aat0240.

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22

"GDCh‐Ortsverband Darmstadt: Neuer Vorsitzender Felix Hausch." Nachrichten aus der Chemie 67, no. 5 (May 2019): 93. http://dx.doi.org/10.1002/nadc.20194088150.

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