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Journal articles on the topic 'HBV co-infection'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Chineze, Helen Ugwu, Nnenna Oketah Edith, Oritsegbubemi Okerentugba Phillip, Frank-Peterside Nnenna, and Omezuruike Okonko Iheanyi. "Serological Evidence of HIV/HBV Co-infection among HIV-infected patients in Onitsha, Anambra State, Nigeria." GSC Biological and Pharmaceutical Sciences 23, no. 3 (2023): 001–8. https://doi.org/10.5281/zenodo.8260283.

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Research suggests that HIV-infected individuals who have also been co-infected with HBV face a greater risk of HIV progression. Hepatitis B and HIV infections pose serious public health challenges in sub-Saharan Africa. This study examined the possible HBV co-infection with the socio-demographic traits of HIV-infected individuals attending the HIV clinic at a referral specialist mission hospital in Onitsha, Anambra State, Nigeria. Two hundred and twenty (220) HIV-infected individuals gave consent to participate in the study. Between March 2022 and October 2022, blood samples (about 5ml) were a

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2

Singh, S. K. "A Correlative Study of Biochemical, Virological & Histological Parameters of HBV Infection in HIV/HBV Co-Infection." Journal of Medical Science And clinical Research 05, no. 05 (2017): 21258–63. http://dx.doi.org/10.18535/jmscr/v5i5.09.

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Sanou-Makan, Konaté, Kayantao Kassoum, Simbo Diakité Seydou, et al. "Frequency of hepatitis and HIV co-infection markers in blood donors at the Hospital Professor Bocar Sidy Sall of Kati-Mali." GSC Biological and Pharmaceutical Sciences 23, no. 2 (2023): 189–96. https://doi.org/10.5281/zenodo.8041517.

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The transmission of infectious agents such as human immunodeficiency virus (HIV), hepatitis B (HBV), and hepatitis C (HCV) represents the greatest threat to the safety of blood transfusion to the recipient. The association of HIV infection with HBV and/or HCV is common worldwide, due to shared modes of transmission. The prevalence of HIV-HBV co-infection is estimated to be 5-10% in the United States and 20-30% in Asia and parts of sub-Saharan Africa. Other studies report HCV co-infection in 9-25% of HIV-infected patients. The aim of this study was to determine the frequency of markers of co-in

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Dr Kar H, Dr Kar H., Dr Bhesania Hodiwala A, and Batazoo A. Batazoo A. "A Study of Co-Infection of HBV in HIV Patients." Indian Journal of Applied Research 4, no. 8 (2011): 507–9. http://dx.doi.org/10.15373/2249555x/august2014/132.

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Ramezani, A., M. Mohraz, A. Aghakhani, et al. "Frequency of isolated hepatitis B core antibody in HIV-hepatitis C virus co-infected individuals." International Journal of STD & AIDS 20, no. 5 (2009): 336–38. http://dx.doi.org/10.1258/ijsa.2008.008377.

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Association between isolated hepatitis B core antibody (anti-HBc) and hepatitis C virus (HCV) infection has been noted in HIV-infected individuals. This study describes the frequency of isolated anti-HBc and its possible value for the detection of HBV-DNA in HIV-infected patients with or without HCV co-infection. Ninety-two HIV-infected patients were enrolled in the study. Hepatitis B surface antigen (HBs Ag), anti-HBs, anti-HBc, anti-HCV, HIV viral load and CD4 count were tested in all subjects. Then we compared 63 subjects with HIV-HCV co-infection with 29 subjects with HIV infection alone r

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Tumpa, Shanjida Islam, and Abdullah Al Mamun. "HIV/HBV Co-infection - A Global Challenge." Bangladesh Journal of Medical Science 14, no. 4 (2015): 316–22. http://dx.doi.org/10.3329/bjms.v14i4.19392.

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With prevalence worldwide approximately 10% of the HIV-infected population is infected with hepatitis B. In persons with HBV and HIV co-infection, HBV-related liver disease progresses more rapidly than in those with HBV mono-infection leading to increased rates of persistent infection, higher HBV DNA levels, increased cirrhosis and liver-related mortality, increased risk of hepatocellular carcinoma, and decreased efficacy of anti-HBV therapy. Furthermore, HIV-infected patients co-infected with HBV have an increased risk for antiretroviral therapy-related hepatotoxicity. The management of hepat

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Garmaeva, Tatyana Ts, Sergey M. Kulikov, Elena A. Michailova, Andrei B. Sudarikov, Felix P. Filatov, and Valeryi G. Savchenko. "Hepatitis B and Hepatitis C Co-Infection in Patients with Hematological Malignancies." Blood 118, no. 21 (2011): 2090. http://dx.doi.org/10.1182/blood.v118.21.2090.2090.

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Abstract Abstract 2090 BACKGROUND. Coinfection with hepatitis B virus (HBV) and hepatitis C virus (HCV) in immunocompromised patients (pts) with hematological malignancies is not well-studied problem. Early recognition of HBV and HCV infectioning incidence in such pts is difficult due to influence of cytostatic and immunosuppressive therapy and possible mutual HBV or HCV inhibitions. Independence of HBV and HCV infection events has to be discussed. AIM. To determine the prevalence of HBV and HCV co-infection in pts with hematological malignancies to check the possible correlation between the i

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Bhattacharya, D., D. Katzenstein, A. Wong, et al. "Alanine aminotransferase levels are not significantly elevated in patients with HIV/HBV co-infection and lamivudine resistance." International Journal of STD & AIDS 19, no. 11 (2008): 780–81. http://dx.doi.org/10.1258/ijsa.2008.008020.

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In hepatitis B virus (HBV) monoinfection, alanine aminotransferase (ALT) levels are linearly correlated with HBV DNA levels and lamivudine resistance. In human immunodeficiency virus (HIV)/HBV co-infection, little is known about the association between ALT, HBV DNA, and lamivudine resistance. We assessed HBV DNA, lamivudine resistance and ALT levels in 45 time points in 11 patients with HIV/HBV co-infection during lamivudine-containing antiretroviral therapy. High HBV DNA levels (>106 copies/mL) and lamivudine resistance developed in 45% and 91% of patients, respectively. However, ALT level

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Ranin, J., D. Salemovic, B. Brmbolic, et al. "Comparison of Demographic, Epidemiological, Immunological, and Clinical Characteristics of Patients with HIV Mono-infection Versus Patients Co-infected with HCV or/and HBV: A Serbian Cohort Study." Current HIV Research 16, no. 3 (2018): 222–30. http://dx.doi.org/10.2174/1570162x16666180717115614.

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Objective:The study aimed to correlate the status of hepatitis C (HCV) and hepatitis B virus (HBV) co-infection in patients with human immunodeficiency virus (HIV) infection with clinical and demographic data prior to starting highly active antiretroviral therapy (HAART) and assess the impact of HCV and HBV co-infection on the natural history of HIV infection.Patients and Methods:The study involved a total of 836 treatment-naive patients with available serological status for HBV and HCV at the point of therapy initiation. Patients were stratified into four groups: HIV mono-infection, HIV/HCV,

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Mendelson, Marc. "Management of HIV-hepatitis B co-infection." Southern African Journal of HIV Medicine 12, no. 1 (2011): 27–33. http://dx.doi.org/10.4102/sajhivmed.v12i1.209.

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HIV-hepatitis B virus (HBV) co-infected patients are at risk of increased morbidity and mortality. Early recognition of dual infection is a critical factor in directing appropriate therapy, and HBV screening should therefore be undertaken at the time of HIV diagnosis. Vaccination against HBV should be considered for all HIV patients who are not yet infected with HBV. Antiretroviral therapy containing two antiretrovirals active against HBV should be started if the patient either has symptomatic liver disease or is asymptomatic with a CD4 count of

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Abubakar, Gana, S. U. Ashafa, and Liman Asabe Suleiman. "Sensitivity of Malaria-HBV Co-Infection Dynamics to Parameter Changes: A Mathematical Analysis." International Journal of Science for Global Sustainability 11, no. 1 (2025): 11–24. https://doi.org/10.57233/ijsgs.v11i1.776.

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Malaria and Hepatitis B Virus (HBV) co-infection pose significant health challenges, particularly in tropical developing countries. This study develops a mathematical model describing the co-infection dynamics of Malaria and HBV diseases in human populations. The model is divided into eleven compartments, and its qualitative analysis reveals the equilibrium points, positivity of solutions, and invariant regions. The disease-free equilibrium point and reproduction numbers are determined, indicating local asymptotic stability. Sensitivity analysis identifies key parameters influencing the co-inf

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12

Volynets, G. V., and A. I. Khavkin. "Co-infection with hepatitis B and C viruses: current state of the problem." Experimental and Clinical Gastroenterology, no. 1 (January 18, 2024): 67–74. http://dx.doi.org/10.31146/1682-8658-ecg-221-1-67-74.

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Co-infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) is a complex clinical disease with an estimated worldwide prevalence of 1-15%. The transmission routes for HCV and HBV are similar. During co-infection, four serological profiles are observed: codominant, HCV dominant, HBV dominant and non-replicative. Although both HBV and HCV replicate in hepatocytes, their life cycles are quite different. Viral replication in co-infected cells is characterized by the dominance of HCV replication over HBV replication. Three theories of interaction between HCV and HBV are discussed. There a

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Park, Heiyoung, Theo Heller, and Barbara Rehermann. "Transcriptome analysis reveals distinct immune response profiles in HBeAg+ and HBeAg− HBV infection and in HBV/HDV co-infection." Journal of Immunology 198, no. 1_Supplement (2017): 158.18. http://dx.doi.org/10.4049/jimmunol.198.supp.158.18.

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Abstract In chronic hepatitis B virus (HBV) infection, HBeAg positivity is associated with an increase in liver inflammation and progression to liver cirrhosis and cancer. Super-infection with hepatitis D virus (HDV) results in more severe liver disease. The causative factors are unknown. To understand the unique immunopathogenesis of HBeAg+ chronic HBV infection and chronic HBV/HDV co-infection, we performed a comparative transcriptome analysis using peripheral blood mononuclear cells of 12 HBV infected patients (6 HBeAg+ vs. 6 HBeAg−), 10 HBV/HDV co-infected patients, and 12 uninfected contr

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Kaswa, Ramprakash, and Marietjie De Villiers. "Prevalence of hepatitis-B virus co-infection among people living with HIV in Mthatha region of South Africa." African Health Sciences 23, no. 1 (2023): 149–56. http://dx.doi.org/10.4314/ahs.v23i1.17.

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Background: Hepatitis-B virus (HBV) co-infection among people living with HIV (PLWH) is highly endemic in South Africa. Despite the availability of an effective vaccine for the last four decades, chronic HBV infection is a major cause of morbidity and mortality among PLWH. Although the incidence of most opportunistic infections has been reduced in individuals with HIV since the implementation of the universal test and treat program in South Africa, HBV co-infection among PLWH is still accounting for high morbidity and mortality. Methodology: This cross-sectional descriptive survey was co

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Tsuge, Masataka, Takuro Uchida, Kevin Walsh, et al. "Early Multiphasic HBV Infection Initiation Kinetics Is Not Clone-Specific and Is Not Affected by Hepatitis D Virus (HDV) Infection." Viruses 11, no. 3 (2019): 263. http://dx.doi.org/10.3390/v11030263.

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Backgrounds and Aims: We previously demonstrated that serum hepatitis B virus (HBV) DNA in HBV infected humanized mice exhibited a highly dynamic multiphasic kinetic pattern from infection initiation to steady-state. Here, we investigated whether this pattern is consistent across different HBV clones or in the presence of hepatitis D virus (HDV) co-infection. Methods: We analyzed early serum viral kinetics using 26 HBV genotype C (GtC) mono-infected mice [clones: PXB, Hiroshima GtC CL4 (CL4) and Hiroshima GtC CL5 (CL5)] and four HBV CL4/HDV genotype one co-infected mice. Results: The HBV kinet

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Kurawa, Muslim Musa, Tasiu Abdullah, Abuhuraira Ado Musa, et al. "Prevalence of Human Immuno-deficiency Virus (HIV) and Hepatitis B Virus (HBV) Co-Infection among People Living with HIV in Dutse Metropolis, Jigawa Nigeria." Dutse Journal of Pure and Applied Sciences 10, no. 1b (2024): 164–73. http://dx.doi.org/10.4314/dujopas.v10i1b.17.

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Hepatitis B virus (HBV) is a known major global public health problem. HBV–HIV co-infection is not uncommon due to shared risk of transmission particularly in areas of endemic HBV infection. The purpose of this study is to assess the prevalence of co-Infection of human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infection among people living with HIV in Dutse metropolis, Jigawa Nigeria. A hospital-based cross-sectional study included 100 confirmed People Living With HIV/AIDS (PLWHA) attending General Hospital Duste, Jigawa. Demographic information, risk factors, and serological an

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Makuza, Jean Damascene, Marie Paul Nisingizwe, Jean Olivier Twahirwa Rwema, et al. "Role of unsafe medical practices and sexual behaviours in the hepatitis B and C syndemic and HIV co-infection in Rwanda: a cross-sectional study." BMJ Open 10, no. 7 (2020): e036711. http://dx.doi.org/10.1136/bmjopen-2019-036711.

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ObjectivesThis study describes the burden of the hepatitis B, C and HIV co-infections and assesses associated risk factors.SettingThis analysis used data from a viral hepatitis screening campaign conducted in six districts in Rwanda from April to May 2019. Ten health centres per district were selected according to population size and distance.ParticipantsThe campaign collected information from 156 499 participants (51 496 males and 104 953 females) on sociodemographic, clinical and behavioural characteristics. People who were not Rwandan by nationality or under 15 years old were excluded.Prima

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TSUCHIYA, N., P. PATHIPVANICH, A. ROJANAWIWAT, et al. "Chronic hepatitis B and C co-infection increased all-cause mortality in HAART-naive HIV patients in northern Thailand." Epidemiology and Infection 141, no. 9 (2012): 1840–48. http://dx.doi.org/10.1017/s0950268812002397.

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SUMMARYA total of 755 highly active antiretroviral therapy (HAART)-naive HIV-infected patients were enrolled at a government hospital in Thailand from 1 June 2000 to 15 October 2002. Census date of survival was on 31 October 2004 or the date of HAART initiation. Of 700 (92·6%) patients with complete data, the prevalence of hepatitis B virus (HBV) surface antigen and anti-hepatitis C virus (HCV) antibody positivity was 11·9% and 3·3%, respectively. Eight (9·6%) HBV co-infected patients did not have anti-HBV core antibody (anti-HBcAb). During 1166·7 person-years of observation (pyo), 258 (36·9%)

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Shih, Yi-Fen, and Chun-Jen Liu. "Hepatitis C Virus and Hepatitis B Virus Co-Infection." Viruses 12, no. 7 (2020): 741. http://dx.doi.org/10.3390/v12070741.

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Hepatitis C virus (HCV) and hepatitis B virus (HBV) co-infection can be encountered in either virus endemic countries. Co-infection can also be found in populations at risk of parenteral transmission. Previous studies demonstrated a high risk of liver disease progression in patients with HCV/HBV co-infection; thus, they should be treated aggressively. Previous evidence recommended therapy combining peginterferon (pegIFN) alfa and ribavirin for co-infected patients with positive HCV RNA. Recent trials further advise using direct-acting antivirals (DAAs) for the clearance of HCV in the co-infect

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Ahmed, Syed Minhaj Uddin, Quazi Manjurul Haque, Kazi Shihab Uddin, and Md Zulfikar Ali. "Viral Hepatitis: HBV-HCV co-infection." KYAMC Journal 14, no. 03 (2024): 178–80. http://dx.doi.org/10.3329/kyamcj.v14i03.68704.

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Co-infection with HBV and HCV is a complex clinical existence which estimated prevalence is reported 0.7% to 16% worldwide. HCV superinfection is very common due to viral replication in HCV is more dominant over HBV. Most of the clinical studies reported that disease progression is faster in HBV and HCV co-infected patients in compare to those with mono-infection. Therefore, early diagnosis and proper treatment is important for withholding the disease progression. Here a case of 45 years old male with fever, anorexia, vomiting and mucus mixed stool. HBsAg and anti-HCV are positive. USG of whol

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Hsu, Cheng-Er, Yen-Chun Liu, Ya-Ting Cheng, et al. "Hepatitis B Co-Infection Has Limited Impact on Liver Stiffness Regression in Chronic Hepatitis C Patients Treated with Direct-Acting Antivirals." Viruses 14, no. 4 (2022): 786. http://dx.doi.org/10.3390/v14040786.

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Introduction: High sustained virological response (SVR) rate (>95%) and liver stiffness regression can be achieved with direct acting antivirals treatment (DAA) in patients with chronic hepatitis C virus (CHC) infection. Reactivation of hepatitis B virus (HBV) was reported during DAA treatment in patients co-infected with HBV, although its impact on liver stiffness remains unknown. This study aims to investigate whether the liver stiffness (LSM) regression is different between HBV/HCV co-infected and mono-HCV-infected patients. Materials and Methods: CHC patients with/without HBV co-infecti

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Shah, N. H., Z. A. Patel, and B. M. Yeolekar. "Vertical Transmission of HIV-HBV Co-infection with Liquor Habit and Vaccination." Malaysian Journal of Mathematical Sciences 16, no. 1 (2022): 119–42. http://dx.doi.org/10.47836/mjms.16.1.10.

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In this paper, the transmission of HIV-HBV co-infection is carried out. The individuals who are infected with both diseases HIV and HBV simultaneously, are said to be HIV-HBV co-infected. These infected individuals have high risk of liver failure. It is the main cause for serious liver complications like cirrhosis and liver cancer at younger age. A deterministic model is considered with liquor habit in men and vaccination to new-borns and carrier mother. Carrier class results in the vertical transmission. In this paper, the transmission dynamics of the model is analyzed. The total population i

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Bejide, Ifeoluwa O., Tolulope A. Kayode, Angel E. Ebagua, et al. "Seroprevalence of Hepatitis B virus and human immunodeficiency virus co-infection in pregnant women from Osun State, Nigeria." Journal of Infection in Developing Countries 18, no. 01 (2024): 145–51. http://dx.doi.org/10.3855/jidc.18704.

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Introduction: Hepatitis B virus and human immunodeficiency virus (HBV/HIV) co-infection is a global health concern due to its significant impact on morbidity and mortality. Reports of HBV/HIV co-infections are increasing in Nigeria, but information on the disease burden in pregnant women and its implications on the fetus is scarce. This study aimed to determine the prevalence of HBV/HIV co-infection in pregnant women. In addition, the study identified the risk factors for the disease in pregnant women attending antenatal clinics in Osun State, Nigeria. Methodology: We collected plasma samples

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Chonco, F. M., and S. Rangiah. "Susceptibility to hepatitis B infection, hepatitis B/HIV co-infections and hepatitis B immunity in HIV-positive patients starting HAART in Durban, South Africa." South African Family Practice 61, no. 2 (2019): 51. http://dx.doi.org/10.4102/safp.v61i2.5004.

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Background: HIV/HBV co-infection remains a global threat to HIV management despite the available effective hepatitis B vaccine and hepatitis B covering antiretroviral therapy. Many studies done in South Africa and internationally showed high prevalence of HIV/hepatitis B co-infection, which mandated routine screening for both infections before initiating HAART. Fewer studies have highlighted the prevalence of hepatitis B susceptibility in the general population starting HAART and most of them were limited to children and high-risk groups. The aim of this study was to demonstrate the extent of

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Elmaghloub, Reem, Ashraf Elbahrawy, Gamal El Didamony, et al. "Hepatitis B virus genotype E infection among Egyptian health care workers." Journal of Translational Internal Medicine 5, no. 2 (2017): 100–105. http://dx.doi.org/10.1515/jtim-2017-0012.

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AbstractBackground and ObjectivesHealth Care Workers (HCWs) are at a high risk of needle stick injuries and HBV infection in Egypt; this problem is further aggravated by low Hepatitis B (HB) vaccination coverage. Limited data are available on the prevalence of HBV infection in Egyptian HCWs. In this study, we aimed to assess the HBV infection rate and genotypes among Egyptian HCWs.MethodsFive hundred and sixty-four (564) HCWs were included. Of them, 258 (45.74%) were health care providers and 306 (54.25%) were non-health care providers. All HCWs completed both the study questionnaires and prov

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Choy, Chiaw Yee, Li Wei Ang, Oon Tek Ng, Yee Sin Leo, and Chen Seong Wong. "Factors Associated with Hepatitis B and C Co-Infection among HIV-Infected Patients in Singapore, 2006–2017." Tropical Medicine and Infectious Disease 4, no. 2 (2019): 87. http://dx.doi.org/10.3390/tropicalmed4020087.

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Co-infection of hepatitis B virus (HBV) and hepatitis C virus (HCV) with human immunodeficiency virus (HIV) is associated with increased risk of hepatic complications and mortality. A retrospective study to estimate the proportion of HBV and HCV co-infections in Singapore was conducted using a clinical database. We included 3065 patients who were seen under the Clinical HIV Programme at the largest referral centre for HIV care between 2006 and 2017 and were tested for both HBV and HCV. Factors associated with HIV-HBV and HIV-HCV co-infections were determined using logistic regressions. The maj

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Alam, Shahinul, Saiful Islam, Asma Helen Khan, et al. "Clinical Practice Guidance for Management of Anti HBc Positive Patients." Journal of Bangladesh College of Physicians and Surgeons 37, no. 4 (2019): 196–201. http://dx.doi.org/10.3329/jbcps.v37i4.43350.

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Hepatitis B core antibody (Anti HBc) is currently considered the most sensitive serological marker for a patient’s history of hepatitis B virus (HBV) infection given its long-term persistence in the bloodstream. The serological pattern of isolated Anti HBc (IAHBc) has been of clinical interest over the past several years.,Thegrowing data of IAHBcsuggestingit as a marker for occult HBV infection (OBI). Occult HBV infection defined as HBV DNA detection in serum or the liver by sensitive diagnostic tests in HBsAg negative individuals with or without serologic markers of previous viral exposure. O

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Tavakoli, Soheila, Wibke Schwerin, Andreas Rohwer, et al. "Phenotype and function of monocyte derived dendritic cells in chronic hepatitis B virus infection." Journal of General Virology 85, no. 10 (2004): 2829–36. http://dx.doi.org/10.1099/vir.0.80143-0.

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The antiviral T cell failure of patients with chronic hepatitis B virus (HBV) infection was suggested to be caused by a T cell stimulation defect of dendritic cells (DC). To address this hypothesis, monocyte derived DC (MDDC) of patients with chronic or resolved acute HBV infection and healthy controls were studied phenotypically by FACS analyses and functionally by mixed lymphocyte reaction, ELISA, ELISpot and proliferation assays of MDDC cultures or co-cultures with an allogeneic HBc-specific Th cell clone. HBV infection of MDDC was studied by quantitative PCR. MDDC from HBV patients seemed

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Nim, Ranjit Kumar, Vivek Kumar Verma, Manoj Kumar, et al. "HIV and hepatitis B co-infection - prevalence and clinical spectrum in a rural tertiary care centre of Northern India." International Journal of Research in Medical Sciences 5, no. 7 (2017): 3154. http://dx.doi.org/10.18203/2320-6012.ijrms20173005.

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Background: HBV and HIV are both endemic in India. Currently, it is not well established what proportion of HIV-positive patients harbours HBV infection in India. No study was done to know the epidemiology of HBV HIV Co infection in rural population of Northern India. So, this study was done to explore the impact of HBV in HIV patients.Methods: Prospective cohort study was conducted on HIV-HBV co infected patients who attended the ART Clinic at ART centre, Department of Medicine, UPUMS, Saifai, Etawah, after obtaining informed consent.Results: Out of these 1751 HIV patients 919 were eligible f

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Osiowy, Carla, Diane Gordon, Jamie Borlang, Elizabeth Giles, and Jean-Pierre Villeneuve. "Hepatitis B virus genotype G epidemiology and co-infection with genotype A in Canada." Journal of General Virology 89, no. 12 (2008): 3009–15. http://dx.doi.org/10.1099/vir.0.2008/005124-0.

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Hepatitis B virus (HBV) genotype G (HBV/G) is an unusual variant, and little is known about its epidemiology and natural history, particularly the requirement for a co-infecting HBV genotype and their relationship during infection. This study investigated the quasispecies nature of co-infecting genotypes in 39 samples collected over a 6 year period from 13 HBV/G-infected patients. HBV/G infections were found to occur predominantly in males (92 %) and were primarily associated with male homosexual sex (67 %). All patients were infected with HBV/G and HBV/A, or a recombinant HBV/A/G strain. Co-i

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Lui, Grace, Terry Yip, Becky Yuen, et al. "358. HIV Infection and the Risk of Hepatocellular Carcinoma in Patients with Hepatitis B Virus (HBV) Co-infection: a Propensity Score-matched Cohort Study." Open Forum Infectious Diseases 6, Supplement_2 (2019): S188. http://dx.doi.org/10.1093/ofid/ofz360.431.

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Abstract Background There is a paucity of data to show whether HIV infection would affect the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus (HBV) infection. Methods A territory-wide cohort study was performed to determine the risk of HCC in patients with HBV with and without HIV co-infection. All patients with HBV/HIV co-infection and HBV mono-infection treated with antiviral therapy in public hospitals in Hong Kong from 2000 to 2017 were identified from an electronic database. Patients with hepatitis C virus (HCV) infection, HCC diagnosed within six months,

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Basso, Maria, Stefan Hohaus, Giulia Bosco, et al. "Hepatitis B Virus (HBV) Reactivation In Anti-HB Core Antigen (anti-HBc) Positive Patients with Hematological Malignancies: A Prospective Multicenter Study." Blood 116, no. 21 (2010): 4911. http://dx.doi.org/10.1182/blood.v116.21.4911.4911.

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Abstract Abstract 4911 Patients with haematological malignancies and overt hepatitis B (HB) infection defined by the presence of HB surface antigen (HBsAg) are at risk of hepatitis reactivation, and antiviral prophylaxis is generally recommended. HBV reactivation can also occur during immunosuppressive therapy in patients who are HBsAg negative, but are positive for antibodies to HB core antigen (anti-HBc) which suggests prior contact with HBV and potential occult infection. The risk of HBV reactivation for these patients who have evidence of viral clearance (HBV-DNA negative) and developed po

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Ould SALEM, Mohamed Lemine, Ahmedna Sidi Abdalla, and Ghaber Sidi Mohamed. "Hepatitis B and Delta Co-Infection: Prevalence and Serological Characteristics in Mauritania." General Medicine and Clinical Practice 5, no. 1 (2022): 01–09. http://dx.doi.org/10.31579/2639-4162/062.

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Background: Hepatitis B is one of the major public health concerns worldwide. In Mauritania, its prevalence in the general population is very high. The hepatitis D virus (HDV) borrows the envelope from the hepatitis B virus (HBV) during its infectious cycle. We thus observe co-infections during which the two viruses are acquired simultaneously and superinfections by HDV in patients who are already chronic carriers of the B virus. Objective: to assess the prevalence of HBV and HDV infection Material and Methods: this is a prospective descriptive study, conducted from January 1 to November 30, 2

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Boyd, Anders, Lorenza N. C. Dezanet, and Karine Lacombe. "Functional Cure of Hepatitis B Virus Infection in Individuals With HIV-Coinfection: A Literature Review." Viruses 13, no. 7 (2021): 1341. http://dx.doi.org/10.3390/v13071341.

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In individuals infected with hepatitis B virus (HBV), the loss of hepatitis B surface antigen (HBsAg) is the ultimate therapeutic goal, which defines “functional cure.” For individuals living with human immunodeficiency virus (HIV), functional cure occurs roughly 2 per 100 person-years during potent anti-HBV containing antiretroviral therapy. Although this rate may be higher than expected in treated HBV mono-infected individuals, rates of functional cure widely vary between studies (0.6–10.5 per 100 person-years). Similar to HBV mono-infection, the phase of HBV infection, HBV (sub-)genotypes a

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Sun, Guofang. "Advances in the Treatment of Human Immunodeficiency Virus and Hepatitis B Virus Co-infection." Infection International 5, no. 2 (2016): 54–58. http://dx.doi.org/10.1515/ii-2017-0131.

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AbstractHepatitis B virus (HBV) and human immunodeficiency virus (HIV) are transmitted through the same pathways. Therefore, the incidence of HBV in the HIV-infected population is higher than that in the healthy population, and is more obvious in China given the high HBV prevalence in the country. HIV and HBV co-infection can accelerate the disease process of HBV. Moreover, the incidence of cirrhosis and end-stage liver disease is higher in patients co-infected with HIV and HBV than in patients infected HBV alone. When treating patients co-infected with HIV and HBV for HBV infection alone, car

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Jemuel, Jesse Banas, and Henry Gabriel Bishop. "Malaria and hepatitis B virus co-infection among pregnant women in Samaru-Zaria, Nigeria." MOJ Public Health 14, no. 1 (2025): 7–12. https://doi.org/10.15406/mojph.2025.14.00464.

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Background: Malaria and Hepatitis B virus (HBV) infection are endemic in Nigeria. These infections pose significant public health concerns, putting the well-being of both an expectant mother and the unborn child at risk. This study was aimed at determining the co-infection and risk factors of malaria and HBV among pregnant women on antenatal visits in selected hospitals within Samaru-Zaria, Nigeria. Methods: A total of 150 pregnant women were included in this study. Structured questionnaires were used to gather data on socio-demographic and risk factors associated with the infections among the

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He, Yaozu, Weiyin Lin, Fei Gu, Xianglong Lan, and Linghua Li. "Co-infection with hepatitis B and human immunodeficiency virus: epidemiology, pathogenesis, and treatment." Infectious Diseases & Immunity 5, no. 1 (2024): 56–61. https://doi.org/10.1097/id9.0000000000000123.

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Abstract Co-infection with hepatitis B virus (HBV) and human immunodeficiency virus (HIV) is common as the modes of disease transmission are similar. HIV affects the development of chronic HBV infection, leading to higher HBV DNA levels, cirrhosis, and end-stage liver duisease, and potentially leading to hepatocellular carcinoma. One of the leading causes of mortality and morbidity in HIV-infected individualsis liver disease, despite the administration of antiretroviral therapy for HIV and HBV. Thus, the screening and follow-up of co-infected patients are vital formonitoring of liver disease p

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Goldin, R., M. McGarvey, S. Dourakis, M. Easton, G. Gill, and HC Thomas. "HBV-DNA polymerase in chronic HBV infection: Co-infection with HIV increases expression." Journal of Hepatology 9 (January 1989): S156. http://dx.doi.org/10.1016/0168-8278(89)90488-1.

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Colagrossi, L., R. Scutari, A. Battisti, et al. "HBV-HDV Co-Infection Constrains HBV Genetic Evolution in HBsAg." Journal of Hepatology 64, no. 2 (2016): S355. http://dx.doi.org/10.1016/s0168-8278(16)00519-5.

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Colagrossi, L., R. Scutari, R. Salpini, et al. "HBV-HDV co-infection constrains HBV genetic evolution in HBsAg." Digestive and Liver Disease 48 (February 2016): e47-e48. http://dx.doi.org/10.1016/j.dld.2015.12.110.

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Gitau, Samuel Nguku, Sudhir Vinayak, Micah Silaba, Rodney Adam, and Reena Shah. "High Prevalence of Liver Fibrosis in Patients with Human Immunodeficiency Virus Monoinfection and Human Immunodeficiency Virus Hepatitis-B Co-infection as Assessed by Shear Wave Elastography: Study at a Teaching Hospital in Kenya." Journal of Clinical Imaging Science 6 (June 7, 2016): 22. http://dx.doi.org/10.4103/2156-7514.183582.

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Objectives: The aim of this study was to determine the prevalence of liver fibrosis in patients with human immunodeficiency virus (HIV) monoinfection versus those with HIV hepatitis-B virus (HBV) co-infection as assessed with shear wave elastography (SWE) in a tertiary sub-Saharan Africa hospital. Materials and Methods: A total of 105 consecutive patients, 70 with HIV monoinfection and 35 with HIV-HBV co-infection, had liver elastography obtained using SWE to assess for the presence of liver fibrosis the cutoff of which was 5.6 kPa. Assessment of aspartate aminotransferase-to-platelet ratio in

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Adesina, Evaristus, Oladokun Omojola, David Imhonopi, Babatunde Adeyeye, Charity Ben-Enukora, and Scholastica Anake. "Information Sources, Knowledge and Practice Towards HIV/ Hepatitis B Co-Infection In Lagos, Nigeria." International Journal of Biology and Biomedical Engineering 15 (July 20, 2021): 285–97. http://dx.doi.org/10.46300/91011.2021.15.34.

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Attaining the objective of healthy lives and wellbeing Sustainable Development Goal 3 is hinged on effective health communication. This study investigates the information source usage, knowledge, attitude and practices of 200 dwellers of Lagos, Nigeria towards HIV/HBV co-infection. In this cross-sectional study, the simple random sampling method was employed in selecting 200 participants in the most populated local government in Lagos state, Nigeria. Questionnaire instrument was created, to elicit responses on four major areas: uses of information sources, knowledge, attitude, health practice

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Oberhardt, Valerie, Maike Hofmann, Robert Thimme, and Christoph Neumann-Haefelin. "Adaptive Immune Responses, Immune Escape and Immune-Mediated Pathogenesis during HDV Infection." Viruses 14, no. 2 (2022): 198. http://dx.doi.org/10.3390/v14020198.

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The hepatitis delta virus (HDV) is the smallest known human virus, yet it causes great harm to patients co-infected with hepatitis B virus (HBV). As a satellite virus of HBV, HDV requires the surface antigen of HBV (HBsAg) for sufficient viral packaging and spread. The special circumstance of co-infection, albeit only one partner depends on the other, raises many virological, immunological, and pathophysiological questions. In the last years, breakthroughs were made in understanding the adaptive immune response, in particular, virus-specific CD4+ and CD8+ T cells, in self-limited versus persis

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Curici, Antoanela, Olivia Mioara Ilie, and Dana Elena Mindru. "Prevalence of HDV, HCV, and HIV Infection in the Population of Patients Infected with HBV in a Romanian Cohort." Microorganisms 13, no. 1 (2025): 118. https://doi.org/10.3390/microorganisms13010118.

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Hepatitis B virus (HBV) infections remain a significant global health challenge, especially in low- and middle-income countries where access to healthcare services is often limited. This study aimed to assess the prevalence of hepatitis B virus (HBV), hepatitis delta virus (HDV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) co-infections in a cohort of 426,528 patients tested for HBsAg in Romania between 2018 and 2023. Of the 17,082 HBsAg-positive individuals (4.0% prevalence), the highest HBV positivity rates were observed in the 30–39 and over 60 age groups. Chronic HBV in

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Asantewaa, Gloria, Nsoh Godwin Anabire, Michael Bauer, et al. "Serum Metabolome Signatures Characterizing Co-Infection of Plasmodium falciparum and HBV in Pregnant Women." Diseases 11, no. 3 (2023): 94. http://dx.doi.org/10.3390/diseases11030094.

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Plasmodium falciparum (P. falciparum) and hepatitis B virus (HBV) co-infection is on the rise among pregnant women in northern Ghana. Mono-infection with either of these two pathogens results in unique metabolic alterations. Thus, we aimed to explicate the effects of this co-infection on the metabolome signatures of pregnant women, which would indicate the impacted metabolic pathways and provide useful prognostic or diagnostic markers. Using an MS/MS-based targeted metabolomic approach, we determined the serum metabolome in pregnant women with P. falciparum mono-infection, HBV mono-infection,

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Alaku, Sarah, Isa Mohammed Haruna, and Grace Rinmecit Pennap. "Prevalence and determinants of hepatitis B virus infection among human immunodeficiency virus patients at a tertiary health care facility in Central Nigeria." World Journal of Advanced Research and Reviews 6, no. 2 (2020): 227–33. https://doi.org/10.5281/zenodo.4313224.

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Hepatitis B virus (HBV) co-infection with human immunodeficiency virus is a major public health problem especially in developing countries. In this study, the prevalence of HBV infection was evaluated among 400 consenting HIV patients accessing healthcare in Federal Medical Center, Keffi, Nigeria using HBsAg detection as the surrogate. Blood samples were collected and screened for HBsAg using ACON screening kit (ACON Laboratories Inc, USA). The Chi-square statistical test was performed to identify possible determining factors associated with the viral infection. Overall, 30 (7.5%) of the parti

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Rana, Urvi, Matt Driedger, Paul Sereda, et al. "Clinical and demographic predictors of antiretroviral efficacy in HIV–HBV co-infected patients." Official Journal of the Association of Medical Microbiology and Infectious Disease Canada 6, no. 2 (2021): 137–48. http://dx.doi.org/10.3138/jammi-2020-0011.

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Background: The clinical and demographic characteristics that predict antiretroviral efficacy among patients co-infected with HIV and hepatitis B virus (HBV) remain poorly defined. We evaluated HIV virological suppression and rebound in a cohort of HIV–HBV co-infected patients initiated on antiretroviral therapy. Methods: A retrospective cohort analysis was performed with Canadian Observation Cohort Collaboration data. Cox proportional hazards models were used to determine the factors associated with time to virological suppression and time to virological rebound. Results: HBV status was avail

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Firnhaber, Cynthia S., and Prue Ive. "Hepatitis B and HIV co-infection in South Africa: Just treat it!" Southern African Journal of HIV Medicine 10, no. 1 (2009): 4. http://dx.doi.org/10.4102/sajhivmed.v10i1.998.

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There are an estimated 350 million hepatitis B carriers worldwide. The prevalence of mono-infection with hepatitis B in South Africa has been estimated at approximately 10% for the rural population and 1% in urban areas. The transmission routes of hepatitis B and HIV are similar, but hepatitis B is more efficient. Co-infection with HIV and hepatitis B is therefore not unusual. Recent studies have shown that the prevalence of HIV/HBV co-infection (using HBV surface antigen (HBsAg) as a marker for HBV) in South Africa ranges from 4.8% to 17%, depending on the population studied.The guidelines fo

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Lima, Leandro Júnior de, Ana Lúcia Lyrio de Oliveira, Valdir Aragão Nascimento, et al. "Hiv And Hepatitis B Virus Co-Infection." International Journal for Innovation Education and Research 9, no. 9 (2021): 99–109. http://dx.doi.org/10.31686/ijier.vol9.iss9.3319.

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The clinical importance of HBV-HIV co-infection comes from the fact that both viruses are highly transmissible and share similar routes of transmission. Co-infected individuals are more likely to develop liver cirrhosis and hepatocellular carcinoma. In view of the above, this manuscript is a quantitative, sectional, descriptive study with secondary data obtained from the analysis of medical records of 88 individuals with chronic hepatitis B. Thus, the purpose of this manuscript is to estimate the frequency of HBV-HIV co-infection and to identify the presence of liver damage. The results reveal

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BUREK, V., J. HORVAT, K. BUTORAC, and R. MIKULIĆ. "Viral hepatitis B, C and HIV infection in Croatian prisons." Epidemiology and Infection 138, no. 11 (2010): 1610–20. http://dx.doi.org/10.1017/s0950268810000476.

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SUMMARYIncarcerated persons comprise about 0·4% of the Croatian population, of whom 25–30% misuse drugs. We attempted to determine the structure of the prison population, prevalence of HBV, HCV, HIV markers, co-infections with HBV, HCV and HIV and acute HBV, HCV and HIV infection. In total, 25·9% of prisoners were positive for some markers for viral hepatitis (HBV 11·3%, HCV 8·3%, HBV/HCV 6·3%). Prevalence of HBV infection in intravenous drug users (IDUs) was 26·2% (highly promiscuous group 20·4%, individuals with psychiatric diseases and personality disorders 16·0%). HCV infection in IDUs was

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