Academic literature on the topic 'HCT 116 Carcinoma'

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Journal articles on the topic "HCT 116 Carcinoma"

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Apaydin, Yildirim Betul. "Anti-cancer, antiproliferative activity of active anionic H2O8 oxygen solution on HCT-116 cancer cell." World Journal of Advanced Research and Reviews 12, no. 2 (2021): 179–84. https://doi.org/10.5281/zenodo.5716648.

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HCT116 cells are adherent epithelial cells derived from the human colorectal carcinoma cell line commonly used to study inflammatory responses in colonic epithelial cells. In this study, it was aimed to evaluate the effects of active anionic H2O8 oxygen solution, which is a very strong antiviral and antimicrobial agent, on HCT-116 human colorectal cancer cell line. Cell viability was determined by MTT analysis. Antiproliferative activity of the anionic H2O8 was investigated on HCT 116 (human colorectal carcinoma) cancer cells. Anionic H2O8 displayed the outstanding activities for MTT test, IC5
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Apaydin Yildirim Betul. "Anti-cancer, antiproliferative activity of active anionic H2O8 oxygen solution on HCT-116 cancer cell." World Journal of Advanced Research and Reviews 12, no. 2 (2021): 179–84. http://dx.doi.org/10.30574/wjarr.2021.12.2.0560.

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HCT116 cells are adherent epithelial cells derived from the human colorectal carcinoma cell line commonly used to study inflammatory responses in colonic epithelial cells. In this study, it was aimed to evaluate the effects of active anionic H2O8 oxygen solution, which is a very strong antiviral and antimicrobial agent, on HCT-116 human colorectal cancer cell line. Cell viability was determined by MTT analysis. Antiproliferative activity of the anionic H2O8 was investigated on HCT 116 (human colorectal carcinoma) cancer cells. Anionic H2O8 displayed the outstanding activities for MTT test, IC5
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Leong, Lek Mun, Kok Meng Chan, Asmah Hamid, Jalifah Latip, and Nor Fadilah Rajab. "Herbal Formulation C168 Attenuates Proliferation and Induces Apoptosis in HCT 116 Human Colorectal Carcinoma Cells: Role of Oxidative Stress and DNA Damage." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/2091085.

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The use of herbal formulations has gained scientific interest, particularly in cancer treatment. In this study, the herbal formulation of interest, denoted as C168, is a mixture of eight genera of plants. This study aims to investigate the antiproliferative effect of C168 methanol extract (CME) on various cancer cells and its underlying mechanism of action on the most responsive cell line, namely, HCT 116 cells. CME exerted antiproliferative activities on HCT 116 colorectal carcinoma cells and HepG2 hepatocellular carcinoma cells but not on CCD-841-CoN normal colon epithelial cells, Jurkat E6.
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Leischner, Christian, Markus Burkard, Anja Michel, et al. "Comparative Analysis of the Antitumor Activity of Cis- and Trans-Resveratrol in Human Cancer Cells with Different p53 Status." Molecules 26, no. 18 (2021): 5586. http://dx.doi.org/10.3390/molecules26185586.

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Resveratrol, a natural plant phytoalexin, is produced in response to fungal infection or− UV irradiation. It exists as an isomeric pair with cis- and trans-conformation. Whereas multiple physiological effects of the trans-form, including a pronounced anti-tumoral activity, are nowadays elucidated, much less knowledge exists concerning the cis-isomer. In our work, we analyzed the antiproliferative and cytotoxic properties of cis-resveratrol in four different human tumor entities in direct comparison to trans-resveratrol. We used human cell lines as tumor models for hepatocellular carcinoma (HCC
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Chandrani, Jeenkal P., and Kalpesh J. Ganatra. "An Efficient And Catalytically Free Chemical Transformation of Pyrimidin-2(1H)-one to 2-(N-Arylamino)pyrimidines and their in vitro Cytotoxicity Evaluation." Asian Journal of Organic & Medicinal Chemistry 5, no. 2 (2020): 133–37. http://dx.doi.org/10.14233/ajomc.2020.ajomc-p260.

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With the aim to develop an efficient strategy to synthesize pyrimidine derivatives bearing diversely substituted amines involves four step linear protocols started with Biginelli multi-component reaction leading to dihydropyrimidines which passing throug multistep sequantial process containing oxidation, chlorination and catalytically free transformation of pyrimidin-2(1H)-one to 2-(N-arylamino)pyrimidines, were evaluated for cytotoxicity study against human cancer lines HCT-116, Hep-G2 and QG-56. Compound 4j exhibit significant anticancer activity showed against: human hepato carcinoma (Hep-G
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Tan, Maria Carmens, Glenn G. Oyong, Chien Chang Shen, and Consolacion Y. Ragasa. "CYTOTOXIC LABDANE DITERPENOIDS FROM ANDROGRAPHIS PANICULATA (BURM.F.) NEES." Asian Journal of Pharmaceutical and Clinical Research 10, no. 12 (2017): 99. http://dx.doi.org/10.22159/ajpcr.2017.v10i12.19194.

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Objective: The primary objective of this study was to probe the cytotoxic capacity of the labdane diterpenoids andrographolide (1), 14-deoxyandrographolide (2), 14-deoxy-12-hydroxyandrographolide (3), and neoandrographolide (4) on mutant and wild-type immortalized cell lines.Methods: Breast adenocarcinoma (MCF-7), colon carcinomas (HCT-116 and HT-29), small cell lung carcinoma (H69PR), human acute monocytic leukemia (THP-1), and wild-type primary normal human dermal fibroblasts - neonatal cells (HDFn) were incubated with 1-4, and the degree of cytotoxicity was analyzed by employing the in vitr
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Budu, Oana, Christian Dragos Banciu, Codruta Soica, et al. "Lacticaseibacillus rhamnosus—A Promising Tool for Colorectal Cancer Treatment." Processes 11, no. 3 (2023): 781. http://dx.doi.org/10.3390/pr11030781.

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Probiotic strains such as Lactobacillus spp. are already known for their beneficial effect on human health and new research supports their role in colon cancer prevention and treatment. The current study reports the effect of different concentrations of Lacticaseibacillus rhamnosus (LGG, 106–109 CFU/mL), alone or in association with 5-fluorouracil (5-FU, 10 μM), tested against normal HaCaT cells, HT-29 colorectal adenocarcinoma and HCT-116 colorectal carcinoma cell lines. The underlying cytotoxic effect was further investigated. LGG treatment of HT-29 and HCT-116 cells caused a variety of apop
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Khulud M Alshehr and Madeha O I Ghobashy. "Antitumor, Antimicrobial activities and Phytochemicals Constituent of different Extracts of Pulicaria undulata (Forssk.) Oliver. Grown Naturally in Saudi Arabia." International Journal of Research in Pharmaceutical Sciences 11, no. 3 (2020): 4889–901. http://dx.doi.org/10.26452/ijrps.v11i3.2790.

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Antitumor and antimicrobial resistance are a habitual global issue, which continually demands finding new natural compounds to encounter the resistance. Pulicaria undulata (Forssk.) Oliver. (Asteraceae family) has numerous promising medicinal properties. The recent work aimed at determination of antitumor effects of three extracts of P. undulata on three types of human carcinoma; HEPG-2 hepatocellular carcinoma, MCF-7 breast carcinoma and HCT-116 colon carcinoma cell lines. Anticancer activity was assessed through studying the viability of the cancer cells and apoptotic pathway. Also, antimicr
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Vaziri, S. A., A. Al-Hazzouri, D. R. Grabowski, M. K. Ganapathi, R. M. Bukowski, and R. Ganapathi. "Sorafenib treatment of clear-cell renal cell carcinoma (CCRCC) and colorectal carcinoma (CRC) cells: Differential effects on gene expression and cell death pathways." Journal of Clinical Oncology 25, no. 18_suppl (2007): 15612. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.15612.

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15612 Background: The von Hippel Lindau gene (VHL) is often mutated in CCRCC and leads to loss of VHL protein (pVHL) expression. Sorafenib is a TKI with clinical activity in metastatic CCRCC. Studies to define mechanisms governing anti-tumor activity of this agent in CCRCC or CRC cell lines that express wild-type pVHL were conducted. Methods: We evaluated CAKI-1 (CCRCC) and HCT- 116/p53 +/+ (CRC) cell lines as model systems expressing wild-type pVHL. Cells were treated at 37°C in an atmosphere of normoxia (21% O2) or hypoxia (1% O2), 5% CO2 and the remainder N2 in the absence (control) or pres
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Kanti Das, Sabuj, Snehasis Mishra, Krishnendu Manna та ін. "A new triazine based π-conjugated mesoporous 2D covalent organic framework: itsin vitroanticancer activities". Chemical Communications 54, № 81 (2018): 11475–78. http://dx.doi.org/10.1039/c8cc07289b.

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Dissertations / Theses on the topic "HCT 116 Carcinoma"

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Kashyap, Srishti. "Isolation, Structure Elucidation and Functional Characterization of a Novel Cytotoxic Secondary Metabolite Phomafuranone, 2-Hydroxy-2, 4-dimethyl-5-[-1-propen-1-yl]-3(2H)-furanone, from Phoma tropica an Endophytic Fungus Isolated from Mappia foetida." Thesis, 2017. http://etd.iisc.ac.in/handle/2005/4135.

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Cancer has become the leading disease-related cause of death in the human population. For example, in the United States, cancer is the second leading cause of death behind cardiovascular disease, and it is projected that cancer will become the leading cause of death in the coming years. The medical treatment of cancer still has many unmet needs. The main curative therapies for cancer, surgery and radiation, are generally only successful if the cancer is found at an early localized stage. Once cancer has progressed to metastatic stage, these therapies are less successful. Hence, chemotherapeuti
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Chung, Ming-Hsien, and 鍾明憲. "Positron Emission Tomography-based study in Hepatocellular carcinoma: 18F-FDG and 11C-MET uptake in HCC cell line." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/78026005703905063226.

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碩士<br>國防醫學院<br>生物及解剖學研究所<br>99<br>Hepatocellular carcinoma (primary liver malignancy or called hepatoma) is the most common type of liver cancer. In Taiwan, the incidence of hepatoma has been estimated to be 27.7 of 100,000 peoples every year. It ranks the first and second cancer-related death in male and female, respectively. The clinical assessment tools for patients with hepatoma include serum alpha-fetoprotein (AFP) check up and several modalities of imaging study. The latter ones consist of sonography, computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomogr
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Book chapters on the topic "HCT 116 Carcinoma"

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Dossoki, Farid I. El, Sarah Rady, Lamiaa A. A. Barakat, and Nasser M. Hosny. "Biosynthesis and Cytotoxicity of Curcumin Loaded on CuO NPs Against Hepatocellular (HEPG-2) and Colorectal (HCT-116) Carcinoma." In Proceedings of The First International Conference on Green Sciences. Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-62672-2_23.

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Conference papers on the topic "HCT 116 Carcinoma"

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Šeklić, Dragana, Milena Jovanović, Nevena Milivojević, and Marko Živanović. "PLATINUM(IV) COMPLEX AND ITS CORRESPONDING LIGAND SUPPRESS CELL MOTILITY AND PROMOTE EXPRESSION OF FRIZZLED-7 RECEPTOR IN COLORECTAL CANCER CELLS." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.288s.

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Suppression of cell movement is an imperative in the effectiveness of future generations of chemotherapeutics. Frizzled 7 receptor (FZD7), as the first protein of Wnt/β-catenin signaling cascade, plays a significant role in regulation of cell differentiation, proliferation, and cell migration. This study aimed to investigate the potential effects of platinum (IV) complex: [PtCl4 (dbu-S, S-eddp)] – C1, and its corresponding ligand – L1 on cell movement, as well as the FZD7 expression and localization after treatments on two human colorectal carcinoma cell lines (HCT-116, SW-480). A Wound healin
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Othmar, Filipe de Santana, Luiza Rayanna Amorim de Lima, Priscilla Barbosa Sales de Albuquerque, and Natalie Emanuelle Ribeiro Rodrigues. "CITOTOXICIDADE DO EXTRATO AQUOSO DE Chrysobalanus icaco EM CÉLULAS DE CARCINOMA COLORRETAL HCT-116." In I Congresso Internacional em Saúde e Desenvolvimento Socioambiental. Even3, 2024. http://dx.doi.org/10.29327/i-congresso-internacional-saude-desenvolvimento-socioambiental.1013205.

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Milenković, Dejan A., Marko N. Živanović, Milan S. Dekić, Marijana Stanojević Pirković, and Jelena R. Đorović Jovanović. "CYTOTOXIC ACTIVITY AND MOLECULAR DOCKING STUDY OF 4- SUBSTITUTED FLAVYLIUM SALT." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.466m.

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In the present manuscript, the cytotoxic activity of flavylium cation substituted at 4- position with phenyl (FC-4Ph) was tested to two cells lines (human colorectal carcinoma, HCT-116, and human fibroblast lung, MRC-5). In vitro cytotoxicity experiments were performed to elucidate the possible anticancer activity of tested substance. Investigated compound did not show cytotoxic effect on HCT-116 after 24 h, while after 72 h exerted significant effect. A significant selectivity towards colorectal carcinoma cells was observed. On the other hand, this compound did not show any effect on MRC-5 ce
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Potočňák, Ivan, Miroslava Litecká, Jitka Prachařová, Monika Hreusová, and Jana Kašpárková. "Anticancer gallium(III) complexes with halogen- and nitroderivatives of 8- hydroxyquinoline." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.451p.

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Six gallium(III) complexes with halogen- or nitroderivatives of 8-hydroxyquinoline, [Ga(ClQ)3] (1), [Ga(BrQ)3] (2), [Ga(dIQ)3] (3), [Ga(CQ)3] (4), [Ga(NQ)3] (5) and [Ga(ClNQ)3]·MeOH were prepared as possible anticancer drugs (HClQ = 5-chloro-8-hydroxyquinoline, HBrQ = 7-bromo-8-roxyquinoline, HdIQ = 5,7-diiodo-8-hydroxyquinoline, HCQ = 5-chloro-7-iodo-8-ydroxyquinoline, HNQ = 5-nitro-8-hydroxyquinoline and HClNQ = 5-chloro-7-nitro-8-hydroxyquinoline). X-ray single crystal structure analysis of [Ga(ClQ)3]·MeOH (1 – MeOH) and 5 showed that both complexes are molecular complexes with Ga(III) coor
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Ekine-Afolabi, Bene Akromaa, Sandra Appiah, Azra Pachenari, and Lucy Ghali. "Abstract LB-271: Inulin inhibits free radical species in HCT 116 adenoma carcinoma and normal human HK (keratinocyte) cell line." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-lb-271.

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Pogorzelska, Aneta, Jarosław Sławiński, and Anna Kawiak. "New N-Benzenesulfonylguanidine Derivatives and Their Selective Growth Inhibition of Human Breast Cancer Cell Line MCF-7 and Colon Carcinoma HCT-116." In ECMC 2022. MDPI, 2022. http://dx.doi.org/10.3390/ecmc2022-13281.

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Lee, Michael J., Robert J. M. Frey, Steven D. Frey, et al. "Abstract LB-21:Taraxacum officinale(common dandelion) inhibits azoxymethane-induced aberrant crypt foci formation in C67BL/6 mice and regulates apoptosis in mice and in human colorectal carcinoma HCT-116 cells." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-lb-21.

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Hotta, Naoki. "IDDF2023-ABS-0005 Hepatocellular carcinoma (HCC) treatment experience using smart fusion in dialysis patients." In Abstracts of the International Digestive Disease Forum (IDDF), Hong Kong, 10–11 June 2023. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2023. http://dx.doi.org/10.1136/gutjnl-2023-iddf.123.

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Xu, Ming Jing, Kit Ho Lai, Shu Hai Lin, et al. "Abstract 1058: Targeting pentose phosphate pathway (PPP) represents a novel therapeutic strategy for hepatocellular carcinoma (HCC) treatment." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1058.

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Cheo, Feng-Yi, Kai-Siang Chan, Wei-Xuan Tay, and Vishal Shelat. "IDDF2022-ABS-0193 Outcomes of preoperative transarterial chemoembolization (TACE) compared to upfront liver resection for large (≥5cm) hepatocellular carcinoma (HCC): a systematic review and meta-analysis." In Abstracts of the International Digestive Disease Forum (IDDF), Hong Kong, 2–4 September 2022. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2022. http://dx.doi.org/10.1136/gutjnl-2022-iddf.119.

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