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Journal articles on the topic 'HDOP'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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1

Tang, Wenjie, Junping Chen, Chao Yu, Junsheng Ding, and Ruyuan Wang. "A New Ground-Based Pseudolite System Deployment Algorithm Based on MOPSO." Sensors 21, no. 16 (2021): 5364. http://dx.doi.org/10.3390/s21165364.

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Pseudolite deployment is the premise of ground-based pseudolite system networking, which affects the coverage and positioning accuracy of ground-based pseudolite systems. Optimal deployment algorithms can help to achieve a higher signal coverage and lower mean horizontal precision factor (HDOP) with a limited number of pseudolites. In this paper, we proposed a multi-objective particle swarm optimization (MOPSO) algorithm for the deployment of a ground-based pseudolite system. The new algorithm combines Digital Elevation Model (DEM) data and uses the mean HDOP of the DEM grid to measure the geo

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Bian, Yuxia, Meizhen Wang, Yongbin Chu, et al. "A Cost Function for the Uncertainty of Matching Point Distribution on Image Registration." ISPRS International Journal of Geo-Information 10, no. 7 (2021): 438. http://dx.doi.org/10.3390/ijgi10070438.

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Computing the homography matrix using the known matching points is a key step in computer vision for image registration. In practice, the number, accuracy, and distribution of the known matching points can affect the uncertainty of the homography matrix. This study mainly focuses on the effect of matching point distribution on image registration. First, horizontal dilution of precision (HDOP) is derived to measure the influence of the distribution of known points on fixed point position accuracy on the image. The quantization function, which is the average of the center points’ HDOP* of the ov

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Wilkinson, Luke A., Kevin B. Vincent, Anthony J. H. M. Meijer, and Nathan J. Patmore. "Mechanistic insight into proton-coupled mixed valency." Chemical Communications 52, no. 1 (2016): 100–103. http://dx.doi.org/10.1039/c5cc07101a.

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Stabilisation of the mixed-valence state in [Mo<sub>2</sub>(TiPB)<sub>3</sub>(HDOP)]<sub>2</sub><sup>+</sup> (HTiPB = 2,4,6-triisopropylbenzoic acid, H<sub>2</sub>DOP = 3,6-dihydroxypyridazine) by electron transfer (ET) is related to the proton coordinate of the bridging ligands.

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Chew, Wi Kang, and Muhammad Aizzat Zakaria. "Outdoor Localisation for Navigation Tracking using Differential Global Positioning System Estimation (DGPS) : Positioning Errors Analysis." Mekatronika 1, no. 2 (2019): 103–14. http://dx.doi.org/10.15282/mekatronika.v1i2.4994.

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    Global Positioning System (GPS) is a very popular outdoor positioning system. Due to the satellites’ errors signal, the Global Positioning System (GPS) receivers determine the accuracy of a current location with about 100 meters in latitude and 156 meters in longitude. In this few years, the technology on autonomous vehicles is rising. Autonomous vehicles need to navigate with high positioning accuracy for preventing any potential danger to road user. So in this paper, Differential Global Positioning System (DGPS) experiment will be introduced for improve the positi

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Akopian, David, Arsen Melkonyan, and C. L. Philip Chen. "Validation of HDOP Measure for Impact Detection in Sensor Network-Based Structural Health Monitoring." IEEE Sensors Journal 9, no. 9 (2009): 1098–102. http://dx.doi.org/10.1109/jsen.2009.2026002.

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Zhao, Xinyang, Qiangqiang Shuai, Guangchen Li, Fangzhou Lu, and Bocheng Zhu. "A Geometric Layout Method for Synchronous Pseudolite Positioning Systems Based on a New Weighted HDOP." ISPRS International Journal of Geo-Information 10, no. 9 (2021): 601. http://dx.doi.org/10.3390/ijgi10090601.

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The positioning accuracy of a ground-based system in an indoor environment is closely related to the geometric configuration of pseudolites. This paper presents a simple closed-form equation for computing the weighted horizontal dilution of precision (WHDOP) with four eigenvalues, which can reduce the amount of calculation. By comparing the result of WHDOP with traditional matrix inversion operation, the effectiveness of WHDOP of the proposed simple calculation method is analyzed. The proposed WHDOP has a linear relationship with the actual static positioning result error in an indoor environm

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Mun, Seung-Hwan, Jong-Woo An, and Jang-Myung Lee. "Robust Positioning Algorithm for a Yard Transporter Using GPS Signals with a Modified FDI and HDOP." International Journal of Precision Engineering and Manufacturing 19, no. 8 (2018): 1107–13. http://dx.doi.org/10.1007/s12541-018-0131-y.

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Gururajan, Srikanth, and Ye Bai. "Autonomous “Figure-8” Flights of a Quadcopter: Experimental Datasets." Data 4, no. 1 (2019): 39. http://dx.doi.org/10.3390/data4010039.

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This article describes the data acquired from multiple flights of a custom-built quadcopter. The Quadcopter was programmed to fly a pre-defined “Figure-8” flight path, at a constant altitude. The data set includes flights with a varying number of waypoints (10 and 15 waypoints in each lobe of the “Figure-8”) and at two different velocities (1.5 and 2.5 m/s). The data also contains information on the output of the flight controller in terms of the Pulse Width Modulation (PWM) signals to each of the four Electronic Speed Controllers (ESC) driving the motors, the recorded outputs of the Inertial

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Vista IV, Felipe P., Deok Jin Lee, and Kil To Chong. "Fusing Multiple Inexpensive GPS Heading Data via Fuzzified Ad-Hoc Weighing." Applied Mechanics and Materials 776 (July 2015): 425–30. http://dx.doi.org/10.4028/www.scientific.net/amm.776.425.

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Applying the same principle behind the Ad-hoc weighing used in fusing data from two inexpensive GPS and an electronic compass (EC) brought up the problem of numerous conditions when trying to fuse data from three GPS devices. Fusing data from two GPS and one EC required at least thirty-two (32) conditions while using three GPS would require 182 conditions that would have entailed a complex set of programming codes. Fuzzy logic was explored as a possible candidate to replace the hard-coding of if-then-statements but still perform the ad-hoc algorithm as desired. The GPS Fix and HDOP (horizontal

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An, Jongwoo, and Jangmyung Lee. "Robust Positioning and Navigation of a Mobile Robot in an Urban Environment Using a Motion Estimator." Robotica 37, no. 08 (2019): 1320–31. http://dx.doi.org/10.1017/s0263574718001534.

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SummaryRobust positioning and navigation of a mobile robot in an urban environment is implemented by fusing the Global Positioning System (GPS) and Inertial Navigation System (INS) data with the aid of a motion estimator. To select and isolate malicious satellite signals and guarantee the minimum number of GPS signals for the localization, an enhanced fault detection and isolation (FDI) algorithm with a short-term memory has been developed in this research. When there are sufficient satellite signals for positioning, the horizontal dilution of precision (HDOP) has been applied for selecting th

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Bian, Yuxia, Xuejun Liu, Meizhen Wang, Hongji Liu, Shuhong Fang, and Liang Yu. "Quantification Method for the Uncertainty of Matching Point Distribution on 3D Reconstruction." ISPRS International Journal of Geo-Information 9, no. 4 (2020): 187. http://dx.doi.org/10.3390/ijgi9040187.

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Matching points are the direct data sources of the fundamental matrix, camera parameters, and point cloud calculation. Thus, their uncertainty has a direct influence on the quality of image-based 3D reconstruction and is dependent on the number, accuracy, and distribution of the matching points. This study mainly focuses on the uncertainty of matching point distribution. First, horizontal dilution of precision (HDOP) is used to quantify the feature point distribution in the overlapping region of multiple images. Then, the quantization method is constructed. H D O P ∗ ¯ , the average of 2 × arc

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Kitt, Wong, Ali Chekima, Jamal Dhargam, Farrah Wong, and Tamer Tabet. "A Framework for Sensor Fusing Using Fuzzy Logic for Navigation Systems." Iraqi Journal for Electrical and Electronic Engineering 6, no. 2 (2010): 83–88. http://dx.doi.org/10.37917/ijeee.6.2.1.

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Navigational sensors are evolving both on a commercial and research level. However, the limitation still lies in the accuracy of the respective sensors. For a navigation system to reach a certain accuracy, multi sensors or fusion sensors are used. In this paper, a framework of fuzzy sensor data fusing is proposed to obtain an optimised navigational system. Different types of sensors without a known state of inaccuracy can be fused using the same method proposed. This is demonstrated by fusing compass/accelerometer and GPS signal. GPS has evolved as a choice of navigation method for outdoor aut

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Jwo, Dah-Jing. "Efficient DOP Calculation for GPS with and without Altimeter Aiding." Journal of Navigation 54, no. 2 (2001): 269–79. http://dx.doi.org/10.1017/s0373463301001321.

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Geometric Dilution Of Precision (GDOP) is a factor that describes the effect of geometry on the relationship between measurement error and position determination error. It is used to provide an indication of the quality of the solution. Conventional closed-form GDOP calculation formula applied to all possible combinations of visible satellites is rather time consuming, especially as the number of satellites grows. Approximations, such as the maximum volume method, are faster but optimum selection is not guaranteed. In this paper, a more concise but efficient solution for the calculation of GDO

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Tang, Xu, Xiufeng He, and Samuel A. Andam-Akorful. "The performance of bds relative positioning usage with real observation data." Boletim de Ciências Geodésicas 20, no. 2 (2014): 223–36. http://dx.doi.org/10.1590/s1982-21702014000200014.

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With the first phase of COMPASS/BeiDou-2 (BDS) completed, the assessment of positioning performance and the characterization of its system are analyzed and presented. Pseudo-range and carrier phase measurements modulated on B1 and B2 have been collected in Shanghai, from 00:00 to 24:00 on 28 December, 2012. Compared with GPS, visibility and measurement quality of BDS's GEO, IGSO and MEO satellites are analyzed. DOP during the whole orbital period is also analyzed the results demonstrate that BDS's HDOP is better than GPS's one, but VDOP opposite. Furthermore, the result of positioning is also

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Marie, Nicolas, Benjamin Aguila, Ahmed Hasbi, Audrey Davis, Philippe Jauzac та Stéphane Allouche. "Different kinases desensitize the human δ-opioid receptor (hDOP-R) in the neuroblastoma cell line SK-N-BE upon peptidic and alkaloid agonists". Cellular Signalling 20, № 6 (2008): 1209–20. http://dx.doi.org/10.1016/j.cellsig.2008.02.010.

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Xia, Xuejuan, Darel Wee Kiat Toh, Kian Keong Poh, et al. "Consuming Wolfberry (Lycium Barbarum L.) with a Healthy Dietary Pattern Improves the Function of Blood Outgrowth Endothelial Cells Derived from Middle-Aged and Older Adults." Current Developments in Nutrition 4, Supplement_2 (2020): 90. http://dx.doi.org/10.1093/cdn/nzaa040_090.

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Abstract Objectives Endothelial progenitor cells (EPCs), a novel biomarker of cardiovascular disease, are involved in the maintenance of endothelial homeostasis and vascular repair and the number of EPCs could be altered by dietary modification. Wolfberry is widely known for the potential cardiovascular benefits, however, its impact on EPC count and function is not reported. This study aims to investigate the effect of consuming wolfberry as part of a healthy dietary pattern (HDP) on the number and function of EPCs derived from blood (BOECs). Methods Twenty-four subjects from Singapore were ra

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Yelton, Steven J., and Brad Schoener. "Research: The Evolution of Healthcare Technology Management in Leading Healthcare Delivery Organizations." Biomedical Instrumentation & Technology 54, no. 2 (2020): 119–24. http://dx.doi.org/10.2345/0899-8205-54.2.119.

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Abstract This descriptive research study examined adaptation to advances in technology by healthcare technology management (HTM) departments in U.S.-based healthcare delivery organizations (HDOs). HDOs that have made or are making significant changes to address this technology evolution were identified through discussions with subject matter experts. Interviews were conducted with HDO leaders responsible for patient care technology and systems. The research described here examined drivers of change, response to change, evolution of strategies, and directions forward. This article shares common

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Meng, Lingdong, Jiexian Wang, Junping Chen, Bin Wang, and Yize Zhang. "Extended Geometry and Probability Model for GNSS+ Constellation Performance Evaluation." Remote Sensing 12, no. 16 (2020): 2560. http://dx.doi.org/10.3390/rs12162560.

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We proposed an extended geometry and probability model (EGAPM) to analyze the performance of various kinds of (Global Navigation Satellite System) GNSS+ constellation design scenarios in terms of satellite visibility and dilution of precision (DOP) et al. on global and regional scales. Different from conventional methods, requiring real or simulated satellite ephemerides, this new model only uses some basic parameters of one satellite constellation. Verified by the reference values derived from precise satellite ephemerides, the accuracy of visible satellite visibility estimation using EGAPM g

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Cui, Haomeng, and Shoujian Zhang. "Satellite Availability and Service Performance Evaluation for Next-Generation GNSS, RNSS and LEO Augmentation Constellation." Remote Sensing 13, no. 18 (2021): 3698. http://dx.doi.org/10.3390/rs13183698.

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Positioning accuracy is affected by the combined effect of user range errors and the geometric distribution of satellites. Dilution of precision (DOP) is defined as the geometric strength of visible satellites. DOP is calculated based on the satellite broadcast or precise ephemerides. However, because the modernization program of next-generation navigation satellite systems is still under construction, there is a lack of real ephemerides to assess the performance of next-generation constellations. Without requiring real ephemerides, we describe a method to estimate satellite visibility and DOP

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McBride, Molly J., Sarah R. Pope, Kai Hu, et al. "Structure and assembly of the diiron cofactor in the heme-oxygenase–like domain of the N-nitrosourea–producing enzyme SznF." Proceedings of the National Academy of Sciences 118, no. 4 (2021): e2015931118. http://dx.doi.org/10.1073/pnas.2015931118.

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In biosynthesis of the pancreatic cancer drug streptozotocin, the tridomain nonheme-iron oxygenase SznF hydroxylates Nδ and Nω′ of Nω-methyl-l-arginine before oxidatively rearranging the triply modified guanidine to the N-methyl-N-nitrosourea pharmacophore. A previously published structure visualized the monoiron cofactor in the enzyme’s C-terminal cupin domain, which promotes the final rearrangement, but exhibited disorder and minimal metal occupancy in the site of the proposed diiron cofactor in the N-hydroxylating heme-oxygenase–like (HO-like) central domain. We leveraged our recent observa

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Jha, Manoj K., and Paul Schonfeld. "Geographic Information System–Based Analysis of Right-of-Way Cost for Highway Optimization." Transportation Research Record: Journal of the Transportation Research Board 1719, no. 1 (2000): 241–49. http://dx.doi.org/10.3141/1719-32.

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At the planning stages of a highway project, various location alternatives must be explored, subject to a set of design constraints. A computerized tool with which to compare alignment alternatives would significantly reduce the time and resources spent as well as help find a minimum cost (or maximum net benefit) solution. Highway design optimization (HDO) is a computerized process that minimizes an objective function composed of significant highway costs, subject to a set of design constraints, including curvature, gradient, and sight distance. Several costs of alignments, such as right-of-wa

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Morrison, Brad E., Nazanin Majdzadeh, Xiaoguang Zhang, et al. "Neuroprotection by Histone Deacetylase-Related Protein." Molecular and Cellular Biology 26, no. 9 (2006): 3550–64. http://dx.doi.org/10.1128/mcb.26.9.3550-3564.2006.

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ABSTRACT The expression of histone deacetylase-related protein (HDRP) is reduced in neurons undergoing apoptosis. Forced reduction of HDRP expression in healthy neurons by treatment with antisense oligonucleotides also induces cell death. Likewise, neurons cultured from mice lacking HDRP are more vulnerable to cell death. Adenovirally mediated expression of HDRP prevents neuronal death, showing that HDRP is a neuroprotective protein. Neuroprotection by forced expression of HDRP is not accompanied by activation of the phosphatidylinositol 3-kinase-Akt or Raf-MEK-ERK signaling pathway, and treat

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Mahashabde, Ruchira, and Chenghui Li. "Nonelderly Adult Cancer Survivors in High Deductible Health Plan: Healthcare Expenditure, Utilization and Access." Healthcare 9, no. 9 (2021): 1090. http://dx.doi.org/10.3390/healthcare9091090.

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Background: To compare healthcare expenditure, utilization and access between nonelderly adult cancer survivors enrolled in a high deductible health plan with a health savings account (“HDHP+HSA”), HDHP without HSA (“HDHP alone”) and low deductible health plan (“LDHP”). Methods: 1735 cancer survivors, aged 18–64 years, with continuous private coverage identified from the 2012–2017 Medical Expenditure Panel Survey: HDHP alone (n = 353), HDHP+HSA (n = 242) and LDHP (n = 1140). Healthcare expenditures, utilization and inability/delay obtaining medical care were analyzed using generalized linear r

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Nguyen, Marie L., Rachel M. Kraft, and John A. Blaho. "Susceptibility of cancer cells to herpes simplex virus-dependent apoptosis." Journal of General Virology 88, no. 7 (2007): 1866–75. http://dx.doi.org/10.1099/vir.0.82868-0.

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Apoptosis has recently been associated with herpes simplex virus 1 (HSV-1) latency and disease severity. There is an intricate balance between pro- and anti-apoptotic processes during HSV-1 infection. When anti-apoptotic pathways are suppressed, this balance is upset and the cells die by apoptosis, referred to here as HSV-1-dependent apoptosis (HDAP). It has been observed previously that HeLa cancer cells exhibit an enhanced sensitivity to HDAP. Here, a series of specific patient-derived cancer cells was utilized to investigate the cell-type specificity of HDAP. The results showed that a human

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Li, Feng, Yaqin Song, Miao Yao, Jun Nie, and Yong He. "Design and properties of novel photothermal initiators for photoinduced thermal frontal polymerization." Polymer Chemistry 11, no. 24 (2020): 3980–86. http://dx.doi.org/10.1039/d0py00305k.

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Three synthesized photothermal initiators (2959-HDHP, 184-HDHP, 1173-HDHP) exhibited better photoinduced thermal frontal polymerization effect than mixture system due to higher heat transfer efficiency from photopolymerization to thermal initiator.

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Gandara, D. R., J. Crowley, R. B. Livingston, et al. "Evaluation of cisplatin intensity in metastatic non-small-cell lung cancer: a phase III study of the Southwest Oncology Group." Journal of Clinical Oncology 11, no. 5 (1993): 873–78. http://dx.doi.org/10.1200/jco.1993.11.5.873.

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PURPOSE To test the concept that cisplatin dose-intensity is important in the treatment of non-small-cell lung cancer (NSCLC), the Southwest Oncology Group (SWOG) performed a randomized trial comparing standard-dose cisplatin (SDCP) 50 mg/m2 days 1 and 8 on a 28-day cycle for eight cycles, high-dose cisplatin (HDCP) 100 mg/m2 days 1 and 8 for four cycles, and high-dose cisplatin plus mitomycin (HDCP-M) 8 mg/m2 day 1. To isolate the effects of dose-intensity versus total dose, the planned cumulative cisplatin dose was 800 mg/m2 in each arm. PATIENTS AND METHODS Between July 1988 and April 1990,

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Santos, Mirela Jeffman dos, Marcelo Gattermann Perin, and Cláudio Hoffmann Sampaio. "O efeito da turbulência tecnológica no sucesso de novos produtos." Estudos do CEPE, no. 43 (January 10, 2016): 119. http://dx.doi.org/10.17058/cepe.v0i43.7639.

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O estudo visa analisar a influência das orientações ao consumidor (OC), à aprendizagem (OA) e à inovação (OI) na habilidade de desenvolvimento de novos produtos (HDNP), e desta no sucesso de novos produtos (SNP), bem como a influência da turbulência tecnológica (TT) na relação entre a HDNP e o SNP. Por meio de levantamento realizado com empresas industriais brasileiras, verificou-se efeito positivo da OC, OA e OI na HDNP e desta no SNP. Constatou-se ainda que a OI é o antecedente de maior efeito na HDNP e que a TT modera positivamente a relação entre a HDNP e o SNP.

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Prajapati, Subhash C., Ratnakar Singh, and Shyam S. Chauhan. "Human dipeptidyl peptidase III regulates G-protein coupled receptor-dependent Ca2+ concentration in human embryonic kidney 293T cells." Biological Chemistry 397, no. 6 (2016): 563–69. http://dx.doi.org/10.1515/hsz-2016-0117.

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Abstract The precise biological function of human dipeptidyl peptidase III (hDPP III) is poorly understood. Using luciferase reporter constructs responsive to change in Ca2+ and/or cAMP and Fura 2-AM fluorometric assay, we show a significant decrease in intracellular Ca2+ following hDPP III overexpression and angiotensin II stimulation in angiotensin II type 1 receptor (G-protein coupled receptor, GPCR) expressing HEK293T cells. Silencing the expression of hDPP III by siRNA reversed the effect of hDPP III overexpression with a concomitant increase in Ca2+. These results, for the first time, sh

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Hiroki, Tomoko, Stephen A. Liebhaber, and Nancy E. Cooke. "An Intronic Locus Control Region Plays an Essential Role in the Establishment of an Autonomous Hepatic Chromatin Domain for the Human Vitamin D-Binding Protein Gene." Molecular and Cellular Biology 27, no. 21 (2007): 7365–80. http://dx.doi.org/10.1128/mcb.00331-07.

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ABSTRACT The human vitamin D-binding protein (hDBP) gene exists in a cluster of four liver-expressed genes. A minimal hDBP transgene, containing a defined set of liver-specific DNase I hypersensitive sites (HSs), is robustly expressed in mouse liver in a copy-number-dependent manner. Here we evaluate these HSs for function. Deletion of HSI, located 5′ to the promoter (kb −2.1) had no significant effect on hDBP expression. In contrast, deletion of HSIV and HSV from intron 1 repressed hDBP expression and eliminated copy number dependency without a loss of liver specificity. Chromatin immunopreci

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Wharam, James, Jamie Wallace, Christine Lu, et al. "Costs after incident breast cancer diagnosis among high-deductible health plan members." Journal of Clinical Oncology 37, no. 27_suppl (2019): 120. http://dx.doi.org/10.1200/jco.2019.37.27_suppl.120.

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120 Background: High-deductible health plans (HDHP) are associated with breast cancer treatment delays of up to 10 months, but their impact on health outcomes is unknown. We hypothesized that, compared with women in generous plans, HDHP members would present with more advanced disease and thus experience higher total costs of early care. Methods: We studied 2004-2014 claims data from a large US health insurer. We included women aged 25-64 who were in traditional low-deductible (≤$500) health plans for 1 baseline year then experienced either an employer-mandated switch to HDHPs (≥$1000) for up

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Williams, Peter E. V. "135 Production of a fifty percent functional protein concentrate from the dry grind ethanol process and use of the product in diets for Atlantic salmon." Journal of Animal Science 98, Supplement_4 (2020): 100. http://dx.doi.org/10.1093/jas/skaa278.183.

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Abstract The corn distilling industry is a major processor of grain, but the high fiber co-product (DDGS), has limited application in feed. Simple mechanical stillage separation downstream of fermentation produces a high protein (52.4 % DM), highly digestible, low crude fiber (4.4% DM) product containing approximately 25% DM spent brewer’s yeast (high density distillers’ protein: HDDP). Currently, approximately 300 ktons of HDDP are produced annually in the USA, and the volume will double in 2020. The effect of graded inclusion levels of HDDP on growth, feed efficiency, nutrient utilization, b

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Lu, Kevin, Sam Li, Jing Yuan, and Minghui Li. "Economics Risks of and Growth of the High Deductible Health Plan Among Patients With Cognitive Impairment." Innovation in Aging 4, Supplement_1 (2020): 102–3. http://dx.doi.org/10.1093/geroni/igaa057.338.

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Abstract OBJECTIVES: High Deductible Health Plan (HDHP) is characterized by higher deductibles and lower monthly premiums. Nevertheless, health economists are concerned that HDHPs may reduce or delay needed care, which will ultimately lead to poorer access to care for chronically affected participants. The objectives of this research are 1) to investigate the HDHP enrollment trend over the past decade; and, 2) to determine the effects of HDHP on risks of financial access risks among adults with cognitive impairment (CI). METHODS: Data were obtained between 2010-2018 from National Health Interv

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Dushanan, R., S. Weerasinghe, D. P. Dissanayake, and R. Senthilnithy. "An In-Silico Approach to Evaluate the Inhibitory Potency of Selected Hydroxamic Acid Derivatives on Zinc-Dependent Histone Deacetylase Enzyme." Journal of Computational Biophysics and Chemistry 20, no. 06 (2021): 603–18. http://dx.doi.org/10.1142/s2737416521500356.

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Histone deacetylase (HDAC) enzymes modify the histone by removing the acetyl group from the lysine residues, known as histone deacetylation. HDACs have been involved in altering gene expressions, resulting in cancer cells in the body. This study focuses on HDAC inhibitors’ impact on histone deacetylase-like protein (HDLP) stability through computational techniques. Molecular dynamics (MD) analyses were used to examine the atomic-level description of drug binding sites and how the HDAC inhibitors change the HDLP enzyme environment. In this study, two hydroxamic acid-derived inhibitors, such as

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Ramadan, Tarek. "SYSTEM-LEVEL, POST-LAYOUT ELECTRICAL ANALYSIS FOR HIGH-DENSITY ADVANCED PACKAGING." Additional Conferences (Device Packaging, HiTEC, HiTEN, and CICMT) 2019, DPC (2019): 000856–77. http://dx.doi.org/10.4071/2380-4491-2019-dpc-presentation_wp1_015.

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INTRODUCTION High-density advanced packaging (HDAP) continues to be the promising “More” in the “More than Moore” approach for improved form factor, functionality, and integration of multiple dies built using different technology nodes. HDAP offerings from outsourced assembly and test (OSAT) companies and foundries are continuously increasing. However, the full commercial productization of such offerings will require the assurance of both an acceptable yield and correct (as intended) functionality. This assurance, like that for integrated circuits (ICs), will come from the availability of prov

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Nguyen, Marie L., Rachel M. Kraft, Martine Aubert, Edward Goodwin, Daniel DiMaio, and John A. Blaho. "p53 and hTERT Determine Sensitivity to Viral Apoptosis." Journal of Virology 81, no. 23 (2007): 12985–95. http://dx.doi.org/10.1128/jvi.01485-07.

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ABSTRACT Apoptosis is a potent host defense against microbes. Most viruses have adapted strategies to counteract this response. Herpes simplex virus (HSV) produces a balance between pro- and antiapoptotic processes during infection. When antiapoptotic signals become limiting, infected cells die through HSV-dependent apoptosis (HDAP). Oncogenic pathways were previously implicated in HDAP susceptibility. Here, we exploited our ability to selectively express all, one, or no oncogenes in the well-defined HeLa cell system to dissect the requirements for HDAP. Human papillomavirus E6 and E7 oncogene

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Zheng, Zhiyuan, Ahmedin Jemal, Matthew P. Banegas, Xuesong Han, and K. Robin Yabroff. "High-Deductible Health Plans and Cancer Survivorship: What Is the Association With Access to Care and Hospital Emergency Department Use?" Journal of Oncology Practice 15, no. 11 (2019): e957-e968. http://dx.doi.org/10.1200/jop.18.00699.

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PURPOSE: To examine the associations among high-deductible health plan (HDHP) enrollment, cancer survivorship, and access to care and utilization. MATERIALS AND METHODS: The 2010 to 2017 National Health Interview Survey was used to identify privately insured adults ages 18 to 64 years (cancer survivors, n = 4,321; individuals without a cancer history, n = 95,316). We used multivariable logistic regressions to evaluate the associations among HDHP/health savings account (HSA) status, delayed/forgone care for financial reasons, and hospital emergency department (ED) visits among cancer survivors

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Pileckyte, Valceckiene, Stoskus, et al. "Dose Intensive Rituximab and High-Dose Methylprednisolone in Elderly or Unfit Patients with Relapsed Chronic Lymphocytic Leukemia." Medicina 55, no. 11 (2019): 719. http://dx.doi.org/10.3390/medicina55110719.

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Background and Objectives: BTK and BCL2 inhibitors have changed the treatment paradigms of high-risk and elderly patients with chronic lymphocytic leukemia (CLL), but their long-term efficacy and toxicity are still unknown and the costs are considerable. Our previous data showed that Rituximab (Rtx) and high-dose methylprednisolone (HDMP) can be an effective and safe treatment option for relapsed high-risk CLL patients. Materials and Methods: We explored the efficacy and safety of a higher Rtx dose in combination with a shorter (3-day) schedule of HDMP in relapsed elderly or unfit CLL patients

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Ochem, Pascal. "Pattern avoidance and HDOL words." Electronic Proceedings in Theoretical Computer Science 63 (August 17, 2011): 30. http://dx.doi.org/10.4204/eptcs.63.5.

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Ban, Željka, Zrinka Karačić, Sanja Tomić, Hashem Amini, Todd B. Marder, and Ivo Piantanida. "Triarylborane Dyes as a Novel Non-Covalent and Non-Inhibitive Fluorimetric Markers for DPP III Enzyme." Molecules 26, no. 16 (2021): 4816. http://dx.doi.org/10.3390/molecules26164816.

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Novel dyes were prepared by simple “click CuAAC” attachment of a triarylborane–alkyne to the azide side chain of an amino acid yielding triarylborane dye 1 which was conjugated with pyrene (dye 2) forming a triarylborane–pyrene FRET pair. In contrast to previous cationic triarylboranes, the novel neutral dyes interact only with proteins, while their affinity to DNA/RNA is completely abolished. Both the reference triarylborane amino acid and triarylborane–pyrene conjugate bind to BSA and the hDPP III enzyme with high affinities, exhibiting a strong (up to 100-fold) fluorescence increase, whereb

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Quesada, Odayme, Ki Park, Janet Wei, et al. "Left ventricular mass and myocardial scarring in women with hypertensive disorders of pregnancy." Open Heart 7, no. 2 (2020): e001273. http://dx.doi.org/10.1136/openhrt-2020-001273.

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AimsHypertensive disorders of pregnancy (HDP) predict future cardiovascular events. We aim to investigate relations between HDP history and subsequent hypertension (HTN), myocardial structure and function, and late gadolinium enhancement (LGE) scar.Methods and resultsWe evaluated a prospective cohort of women with suspected ischaemia with no obstructive coronary artery disease (INOCA) who underwent stress/rest cardiac magnetic resonance imaging (cMRI) with LGE in the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction study. Self-reported history of pregnancy and HDP (gestationa

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Wen, Timothy, Noelle Breslin, Eve E. Overton, et al. "Risk of Stillbirth after Antepartum Hospitalization for Hypertensive Diseases of Pregnancy." American Journal of Perinatology 37, no. 01 (2019): 066–72. http://dx.doi.org/10.1055/s-0039-1697589.

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Abstract Objective To determine if women with an antepartum admission for hypertensive diseases of pregnancy (HDP) were at increased risk for stillbirth. Study Design This study utilized the 2010 to 2014 Nationwide Readmissions Database. Antepartum admissions with HDP were identified and linked to subsequent delivery hospitalizations. Delivery hospitalizations with HDP without a preceding antepartum HDP admission were also identified. Risk for stillbirth, abruption, or both was compared between these two groups. Results An estimated 382,621 deliveries with an HDP diagnosis were identified of w

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Semenenya, I. N., A. A. Astrouski, A. V. Shuriberko, and Yu E. Razvodovsky. "lipid composition of blood plasma high density lipoproteins as marker of metabolic reactions of urgent adaptations under acute stress." Doklady of the National Academy of Sciences of Belarus 64, no. 5 (2020): 583–89. http://dx.doi.org/10.29235/1561-8323-2020-64-5-583-589.

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The article substantiates the mechanisms and significance of the increased contents of blood plasma cholesterol and high density lipoproteins (HDLP) under acute exposure to stress factors leading to activation of metabolism. To a great extent, these changes reflect the adaptation rearrangements in cell membranes that are predominantly haracterized by a decreased content of free cholesterol in their composition due to its efflux to HDLP particles . The changes in HDLP fatty acid composition also contribute to this process resulting in a reduction of membrane microviscosity so that to intensify

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Merriam, Audrey, Julley Jung, Cynthia Gyamfi-Bannerman, and Devin Smith. "Effect of Maternal Age and Fetal Number on the Risk of Hypertensive Disorders of Pregnancy." American Journal of Perinatology 35, no. 03 (2017): 311–16. http://dx.doi.org/10.1055/s-0037-1607297.

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Objective Our primary objective was to compare the differential contribution of fetal number and maternal age to the risk of hypertensive disorders of pregnancy (HDP). Study Design This was a secondary analysis of a large study of primary cesarean delivery. Women with singleton, twin, or triplet gestations were included. Women were divided into groups based on fetal number and maternal age. The primary outcome was HDP. A logistic regression model was fit to adjust for confounders. The incidence of HDP was compared with the reference group and within exposure groups. Results Of the 70,417 women

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Leal, Lisiane Freitas, Sonia Marzia Grandi, Vanessa Iribarrem Avena Miranda, et al. "Hypertensive Disorders of Pregnancy and Medication Use in the 2015 Pelotas (Brazil) Birth Cohort Study." International Journal of Environmental Research and Public Health 17, no. 22 (2020): 8541. http://dx.doi.org/10.3390/ijerph17228541.

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Hypertensive disorders of pregnancy account for approximately 22% of all maternal deaths in Latin America and the Caribbean. Pharmacotherapies play an important role in preventing and reducing the occurrence of adverse outcomes. However, the patterns of medications used for treating women with hypertensive disorders of pregnancy (HDP) living in this country is unclear. A population-based birth cohort study including 4262 women was conducted to describe the pattern of use of cardiovascular agents and acetylsalicylic acid between women with and without HDP in the 2015 Pelotas (Brazil) Birth Coho

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Umeh, Chinedu, and Simona Ionita. "Audit of high dose antipsychotic prescribing in the havering community recovery team." BJPsych Open 7, S1 (2021): S354—S355. http://dx.doi.org/10.1192/bjo.2021.939.

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AimsThe main aim of this audit was to determine the prevalence of HDAP in Havering Community Recovery Team (CRT). The secondary aim was to determine how well HDAP has been monitored and documented - specifically, whether discussions around the reasons for continuing and the risks and benefits have been discussed.BackgroundThere is a focus to reduce high dose antipsychotic prescribing (HDAP) due to the lack of evidence that it is efficacious and that smaller doses have an equivalent effect and are better tolerated. Similarly, the consensus by the Royal College of Psychiatrists is that any presc

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WILLIAMS-CAMPBELL, ANISHA M., and MORSE B. SOLOMON. "Reduction of Spoilage Microorganisms in Fresh Beef Using Hydrodynamic Pressure Processing." Journal of Food Protection 65, no. 3 (2002): 571–74. http://dx.doi.org/10.4315/0362-028x-65.3.571.

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Hydrodynamic pressure processing (HDP) was investigated as a technology to reduce spoilage microorganisms found in fresh beef. In two separate studies (studies 1 and 2), retail ground beef and beef roasts were purchased (day 0). The roasts were divided into stew pieces (30 to 40 g). All meat samples, including control samples, were stored at 5°C for 20 h in a plastic film. After storage, designated samples were treated with HDP. In study 3, ground beef was treated with HDP (day 0) and stored aerobically (5°C) for 14 days with control samples. Each meat type was vacuum-packaged for HDP (100 g b

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Arnott, Clare, Michael Nelson, Maria Alfaro Ramirez, et al. "Maternal cardiovascular risk after hypertensive disorder of pregnancy." Heart 106, no. 24 (2020): 1927–33. http://dx.doi.org/10.1136/heartjnl-2020-316541.

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Background and objectiveHypertensive disorders of pregnancy (HDPs) affect 5%–10% of pregnancies and have been associated with excess maternal cardiovascular disease (CVD) risk. The primary aim of this study was to reliably estimate absolute and relative risks of CVD after HDP.MethodsA retrospective cohort of women who had singleton pregnancies in New South Wales, Australia, between 2002 and 2016 and identified using linked population health administrative databases. The primary exposure was new-onset HDP (pre-eclampsia/eclampsia and gestational hypertension), and the endpoint was hospitalisati

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Morrison, Brad E., and Santosh R. D’Mello. "Polydactyly in Mice Lacking HDAC9/HDRP." Experimental Biology and Medicine 233, no. 8 (2008): 980–88. http://dx.doi.org/10.3181/0802-rm-48.

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Shlachter, J. S. "Solid D2fiber experiments on HDZP-II." Plasma Physics and Controlled Fusion 32, no. 11 (1990): 1073–81. http://dx.doi.org/10.1088/0741-3335/32/11/017.

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Bohlander, George W. "Constructive Discharge—A. K. A. Was it a Quit or a Discharge? Understanding the Doctrine and Prevention of Constructive-Discharge Cases." Journal of Individual Employment Rights 8, no. 1 (1999): 47–59. http://dx.doi.org/10.2190/hdup-d097-2ebt-ge3x.

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