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Dissertations / Theses on the topic 'HDR brachytherapy'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Holm, Åsa. "Mathematical Optimization of HDR Brachytherapy." Doctoral thesis, Linköpings universitet, Optimeringslära, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-99795.

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One out of eight deaths throughout the world is due to cancer. Developing new treatments and improving existing treatments is hence of major importance. In this thesis we have studied how mathematical optimization can be used to improve an existing treatment method: high-dose-rate (HDR) brachytherapy. HDR brachytherapy is a radiation modality used to treat tumours of for example the cervix, prostate, breasts, and skin. In HDR brachytherapy catheters are implanted into or close to the tumour volume. A radioactive source is moved through the catheters, and by adjusting where the catheters are pl

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2

Kolkman-Deurloo, Inger Karine Kirsten. "Intraoperative HDR brachytherapy: present and future." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2007. http://hdl.handle.net/1765/8621.

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3

Amoush, Ahmad A. "Error Analysis of non-TLD HDR Brachytherapy Dosimetric Techniques." University of Cincinnati / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1307105202.

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4

Toye, Warren, and michelletoye@optusnet com au. "HDR Brachytherapy: Improved Methods of Implementation and Quality Assurance." RMIT University. Applied Sciences, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080528.091630.

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This thesis describes experimental work performed (1998-2001) during the author's involvement with the Brachytherapy group at the Peter MacCallum Cancer Centre (PMCC), where he was employed by its Department of Physical Sciences and subsequent modeling and analytical studies. When PMCC added HDR brachytherapy to its radiation therapy practice, an existing operating suite was considered the ideal location for such procedures to be carried out. The integration of brachytherapy into the theatre environment was considered logical due to the relatively invasive nature of brachytherapy techniques an

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5

Aldelaijan, Saad. "Reference dosimetry of HDR Ir-192 brachytherapy source using radiochromic film." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95205.

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A protocol of establishing radiochromic film based reference dosimetry for high dose rate Ir-192 brachytherapy source was assessed and described. A comparison between calibration curves created in water and Solid Water are provided. Solid Water was shown to be a viable alternative to water in establishing calibration curve for Ir-192 radiation beam. A Monte Carlo correction factor was calculated to convert the dose to water into dose to Solid Water and the experimental methods that we performed agreed with the Monte Carlo results where the ratio (DSW/DW)Ir-192 was found to be 0.9808 ± 0.14% (1

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6

Williams, Eric. "Dose Modification Factor Analysis of Multi-Lumen Brachytherapy Applicator with Monte Carlo Simulation." University of Toledo Health Science Campus / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=mco1352570600.

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7

Shum, Tsz-hang, and 岑梓恆. "A high spatial and temporal resolutions quality assurance tool for checking the accuracy of HDR source dwell positions and times." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193526.

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In High Dose Rate (HDR) brachytherapy, treatment dose to patients is highly dependent on the accuracy of positioning and duration of the source. Source misplacement or wrong duration of treatment could potentially result in adverse clinical side effects to patients. In order to maintain successful treatment for patients, an independent Quality Assurance (QA) verification is crucial to measure the High Dose Rate (HDR) source positioning and dwell time periodically to ensure the prescribed dose is correct and safe for brachytherapy treatment. The current QA practice used to validate the accur

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8

Fonseca, Gabriel Paiva. "Modelagem pelo método de Monte Carlo do paciente e das complexidades dos tratamentos braquiterápicos com alta taxa de dose." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/85/85133/tde-06012016-155103/.

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Tratamentos braquiterápicos são comumente realizados conforme o relatório da American Association of Physicists in Medicine (AAPM), Task Group report TG-43U1, o qual define o formalismo para cálculo de dose absorvida na água e não considera a composição dos materiais, densidades, dimensões do paciente e o efeito dos aplicadores. Estes efeitos podem ser significantes, conforme descrito pelo recente relatório da AAPM, Task Group report TG- 186, que define diretrizes para que sistemas de planejamento modernos, capazes de considerar as complexidades descritas acima, sejam implementados. Esta tese

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9

Hliziyo, Freedom. "Dose intercomparisons between computer planning, in-vivo and phantom measurements for Iridium-192 HDR Brachytherapy." Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/2800.

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During gynaecological high-dose rate (HDR) intracavitary brachytherapy (ICBT), invivo dosimetry is done to monitor the dose received by the bladder and rectum. This study was aimed at validating the need to do in-vivo dosimetry during ICBT. Thirty patients were recruited to participate in the study. Treatment setup data from the thirty patients was used to reproduce applicator and in-vivo diode treatment setups in a water phantom. Radiation doses administered to the patients were replicated in the water phantom to measure the doses at marked dose reference positions.

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10

Macey, Nathaniel J. "Evaluation of a MapCHECK2^TM Diode Array for High Dose Rate Brachytherapy Quality Assurance." University of Toledo Health Science Campus / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=mco1430301747.

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11

Moosavi, Askari Reza, and Askari Reza Moosavi. "A quality control tool for HDR prostate brachytherapy based on patient-specific geometry and stochastic frontier analysis." Master's thesis, Université Laval, 2019. http://hdl.handle.net/20.500.11794/37078.

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Cette étude porte sur le développement d’un outil de contrôle qualité basé sur l’expérience, dérivé du concept de frontière stochastique en économie et s’appuyant sur des connaissances géométriques spécifiques au patient pour améliorer la qualité des traitements de curiethérapie à haut débit de dose pour le cancer de la prostate. Cent plans cliniques de curiethérapie à haut débit de dose de la prostate ont été utilisés dans cette étude, dans laquelle l’échographie transrectale était la seule modalité d’imagerie. Une fraction unique de 15 Gy a était prescrite à tous ces patients. Un algorithme

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12

König, Tim [Verfasser], and Klaus [Gutachter] Tönnies. "Computer-assisted image registration for HDR brachytherapy of the liver in MRI / Tim König ; Gutachter: Klaus Tönnies." Magdeburg : Universitätsbibliothek Otto-von-Guericke-Universität, 2019. http://d-nb.info/1219965383/34.

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13

Moosavi, Askari Reza. "A quality control tool for HDR prostate brachytherapy based on patient-specific geometry and stochastic frontier analysis." Master's thesis, Université Laval, 2019. http://hdl.handle.net/20.500.11794/37078.

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Cette étude porte sur le développement d’un outil de contrôle qualité basé sur l’expérience, dérivé du concept de frontière stochastique en économie et s’appuyant sur des connaissances géométriques spécifiques au patient pour améliorer la qualité des traitements de curiethérapie à haut débit de dose pour le cancer de la prostate. Cent plans cliniques de curiethérapie à haut débit de dose de la prostate ont été utilisés dans cette étude, dans laquelle l’échographie transrectale était la seule modalité d’imagerie. Une fraction unique de 15 Gy a était prescrite à tous ces patients. Un algorithme

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14

König, Tim Verfasser], and Klaus [Gutachter] [Tönnies. "Computer-assisted image registration for HDR brachytherapy of the liver in MRI / Tim König ; Gutachter: Klaus Tönnies." Magdeburg : Universitätsbibliothek Otto-von-Guericke-Universität, 2019. http://d-nb.info/1219965383/34.

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15

Bondal, Aditya. "REAL TIME 3-D TRACKING OF THE HIGH DOSE RATE RADIATION SOURCE USING A FLAT PANEL DETECTOR." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/2236.

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A number of QA procedures have been developed for Breast Brachytherapy treatments, yet none guarantee accurate dose delivery or allow conformation of the actual source position leading to errors sometimes going unnoticed. The objective of this study is to track the exact path the HDR source would follow in real time. The exit radiation of the HDR source was used to image a well defined matrix of markers. The images were acquired using FPD and were processed to obtain projection coordinates while an x-ray calibration image was processed to obtain marker coordinates. Each marker along with its

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16

Howie, Andrew Gordon, and howie andrew@gmail com. "Improving high dose rate and pulsed dose rate prostate brachytherapy - alternative prostate definition and treatment delivery verification methods." RMIT University. Applied Sciences, 2009. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20091007.091553.

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Brachytherapy is a form of radiotherapy in which radioactive sources are placed at short distances from, or even inside the target volume. The use of high dose rate brachytherapy is a widely accepted and clinically proven treatment for some stages of prostate cancer. The aim of this project was to investigate potential improvements on two of the most important aspects of high dose rate (HDR) and pulsed dose rate (PDR) prostate brachytherapy - prostate definition and treatment delivery verification. The use of magnetic resonance (MR) imaging in addition to the conventional compu

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17

Wong, Tony Po Yin, and tony wong@swedish org. "Improving Treatment Dose Accuracy in Radiation Therapy." RMIT University. Applied Sciences, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080104.144139.

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The thesis aims to improve treatment dose accuracy in brachytherapy using a high dose rate (HDR) Ir-192 stepping source and in external beam therapy using intensity modulated radiation therapy (IMRT). For HDR brachytherapy, this has been achieved by investigating dose errors in the near field and the transit dose of the HDR brachytherapy stepping source. For IMRT, this study investigates the volume effect of detectors in the dosimetry of small fields, and the clinical implementation and dosimetric verification of a 6MV photon beam for IMRT. For the study of dose errors in the near field o

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18

Wolf, Sabine Charlotte [Verfasser]. "Inverse Dosisoptimierung für die HDR-Brachytherapie des Prostatakarzinoms / Sabine Charlotte Wolf." Kiel : Universitätsbibliothek Kiel, 2013. http://d-nb.info/104218559X/34.

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19

Broschk, Janina [Verfasser]. "Effektivität und Sicherheit der HDR-Brachytherapie in der Therapie des Prostatakarzinoms / Janina Broschk." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2017. http://d-nb.info/1133311180/34.

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20

Müller, Klaudia [Verfasser]. "Biologische Bestrahlungsplanung in der HDR-Brachytherapie beim Prostatakarzinom : Fiktion oder Realität / Klaudia Müller." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2017. http://d-nb.info/1140605046/34.

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21

Heydemann-Obradovic, Antonela. "Tumorkontrolle und Spätfolgen nach alleiniger vaginaler HDR-Brachytherapie in der adjuvanten Behandlung des operierten Endometriumkarzinoms." kostenfrei, 2008. http://mediatum2.ub.tum.de/doc/630257/630257.pdf.

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22

Neumann, Sophie [Verfasser], Marino [Gutachter] Venerito, and Walter A. [Gutachter] Wohlgemuth. "Sicherheit und Effektivität der CT-gestützten HDR-Brachytherapie von abdominalen Lymphknotenmetastasen / Sophie Neumann ; Gutachter: Marino Venerito, Walter A. Wohlgemuth." Magdeburg : Universitätsbibliothek Otto-von-Guericke-Universität, 2020. http://d-nb.info/1237047420/34.

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23

Sieber, Fabian [Verfasser], Thorsten [Gutachter] Walles, and Nikolaos [Gutachter] Tselis. "Sicherheit und Effektivität der CT-gestützten interstitiellen HDR-Brachytherapie primärer und sekundärer Lungenmalignome / Fabian Sieber ; Gutachter: Thorsten Walles, Nikolaos Tselis." Magdeburg : Universitätsbibliothek Otto-von-Guericke-Universität, 2019. http://d-nb.info/1228071632/34.

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24

Touet, Amadeo [Verfasser], Frank [Gutachter] Meyer, and Bernhard [Gutachter] Gebauer. "Volumenänderungen des linken Leberlappens (Segment II/III) nach CT-gesteuerter interstitieller HDR-Brachytherapie des rechten Leberlappens / Amadeo Touet ; Gutachter: Frank Meyer, Bernhard Gebauer." Magdeburg : Universitätsbibliothek Otto-von-Guericke-Universität, 2020. http://d-nb.info/1228071683/34.

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25

Touet, Amadeo Verfasser], Frank [Gutachter] [Meyer, and Bernhard [Gutachter] Gebauer. "Volumenänderungen des linken Leberlappens (Segment II/III) nach CT-gesteuerter interstitieller HDR-Brachytherapie des rechten Leberlappens / Amadeo Touet ; Gutachter: Frank Meyer, Bernhard Gebauer." Magdeburg : Universitätsbibliothek Otto-von-Guericke-Universität, 2020. http://d-nb.info/1228071683/34.

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26

Utzig, Dorothea [Verfasser], G. [Akademischer Betreuer] Hänsgen, J. [Akademischer Betreuer] Dunst, and H. [Akademischer Betreuer] Schmidberger. "Ergebnisse und Analyse der primären perkutanen Strahlentherapie des Uteruszervixkarzinoms in Kombination mit HDR-Brachytherapie / Dorothea Utzig. Betreuer: G. Hänsgen ; J. Dunst ; H. Schmidberger." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2010. http://d-nb.info/1025134753/34.

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27

Strouthos, Iosif [Verfasser], Nikolaos [Gutachter] Tselis, and Friedhelm E. [Gutachter] Zanella. "Wertigkeit der interstitiellen HDR-Brachytherapie bei der Behandlung des lokalisierten Prostatakarzinoms: Offenbacher Ergebnisse mit einem fraktionierten Monotherapieprotokoll / Iosif Strouthos ; Gutachter: Nikolaos Tselis, Friedhelm E. Zanella." Frankfurt am Main : Universitätsbibliothek Johann Christian Senckenberg, 2018. http://d-nb.info/1156326605/34.

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28

Drewes, Ralph [Verfasser], Frank [Gutachter] Fischbach, and Patrick [Gutachter] Asbach. "Evaluierung der Effektivität der bildgeführten, interstitiellen HDR-Brachytherapie in der Behandlung gastrointestinaler, hepatisch und peritoneal metastasierter Tumorentitäten : [kumulative Dissertation] / Ralph Drewes ; Gutachter: Frank Fischbach, Patrick Asbach." Magdeburg : Universitätsbibliothek Otto-von-Guericke-Universität, 2020. http://d-nb.info/1220035971/34.

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29

Schütze, Annette [Verfasser], Jürgen [Akademischer Betreuer] Füller, Thomas G. [Akademischer Betreuer] Wendt, and Heiko [Akademischer Betreuer] Wunderlich. "Vergleich der Akut- und Spättoxizität zwischen interstitieller HDR-Brachytherapie in Kombination mit perkutaner Strahlentherapie des Prostatakarzinoms / Annette Schütze. Gutachter: Jürgen Füller ; Thomas G. Wendt ; Heiko Wunderlich." Jena : Thüringer Universitäts- und Landesbibliothek Jena, 2014. http://d-nb.info/104943787X/34.

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30

Drewes, Ralph [Verfasser], Frank [Gutachter] Fischbach, and Patrick Rainer [Gutachter] Asbach. "Evaluierung der Effektivität der bildgeführten, interstitiellen HDR-Brachytherapie in der Behandlung gastrointestinaler, hepatisch und peritoneal metastasierter Tumorentitäten : [kumulative Dissertation] / Ralph Drewes ; Gutachter: Frank Fischbach, Patrick Asbach." Magdeburg : Universitätsbibliothek Otto-von-Guericke-Universität, 2020. http://nbn-resolving.de/urn:nbn:de:gbv:ma9:1-1981185920-339001.

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31

Jährig, Philip Leonard [Verfasser], György [Akademischer Betreuer] Kovacs, and Andreas [Gutachter] Böhle. "Darstellungsgenauigkeit verschiedener Applikatoren in TRUS, CT, CBCT und MRT zur Planung der interstitiellen HDR-Brachytherapie des Prostata-Ca / Philip Leonard Jährig ; Gutachter: Andreas Böhle ; Akademischer Betreuer: György Kovacs." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2020. http://d-nb.info/1207339768/34.

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32

Ade, Nicholas. "Transit dosimetry in 192Ir high dose rate brachytherapy." Thesis, 2010. http://hdl.handle.net/10539/8905.

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Background and purpose: Historically HDR brachytherapy treatment planning systems ignore the transit dose in the computation of patient dose. However, the total radiation dose delivered during each treatment cycle is equal to the sum of the static dose and the transit dose and every HDR application therefore results in two radiation doses. Consequently, the absorbed dose to the target volume is more than the prescribed dose as computed during treatment planning. The aim of this study was to determine the magnitude of the transit dose component of two 192Ir HDR brachytherapy units and ass

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33

Dempsey, Claire Louise. "Technology assessment and quality improvement in a clinical HDR brachytherapy setting." Thesis, 2014. http://hdl.handle.net/1959.13/1055829.

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Research Doctorate - Doctor of Philosophy (PhD)<br>High dose rate (HDR) brachytherapy is a form of radiation therapy in which the source of radiation is placed into, or as close as possible to, a cancerous tumour. Brachytherapy was first applied over 100 years ago and has been evolving and refining ever since. Often problems with introduction of new HDR brachytherapy technology and techniques into clinical departments are the lack of published guidelines regarding effective and safe implementation. Instigating change should involve systematic analysis of individual processes to improve patient

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34

Govender, Natalie. "2D brachytherapy planning versus 3D brachytherapy planning for patients with cervical cancer." Thesis, 2015. http://hdl.handle.net/10321/1258.

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Submitted in fulfillment of the requirements of the degree of the Master of Technology : Radiography, Durban University of Technology, 2014.<br>Research Aims The purpose of this study is to compare 2D HDR Brachytherapy planning and 3D HDR Brachytherapy planning in terms of dose distribution in order to accurately determine bladder and rectal doses. Further research questions were explored to determine whether relationships existed between Computer Tomography volumes and bladder and rectum dose. Methodology The 30 female patients that volunteered for the study were conveniently selected.

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35

Lopes, Ana Rita Gomes. "HDR brachytherapy as monotherapy for low risk prostate cancer: dosimetric and clinical evaluation." Master's thesis, 2016. http://hdl.handle.net/10451/24921.

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Tese de mestrado integrado, Engenharia Biomédica e Biofísica (Radiações em Diagnóstico e Terapia)Universidade de Lisboa, Faculdade de Ciências, 2016<br>Na Europa, o cancro da próstata é um dos tumores malignos mais comum nos homens. A idade média no diagnóstico é de 65 anos, raramente sendo este tumor diagnosticado antes dos 50 anos. Em Portugal, segundo a Direção Geral de Saúde, a taxa de incidência de cancro da próstata ´e aproximadamente 82 casos por 100 000 habitantes. Na Holanda, 11 158 novos casos de cancro da próstata são diagnosticados por ano. A radioterapia tem vindo a ocupar um luga

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36

Kefala, Vasiliki. "Radiobiological models based evaluation of the consequences of potential systematic catheter shifts in the HDR brachytherapy of prostate cancer." Thesis, 2009. http://nemertes.lis.upatras.gr/jspui/handle/10889/2777.

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Τhe purpose of this study is to investigate and analyze the influence of the possible errors eventually occurring in a 3D-US based HDR Brachytherapy of prostate cancer on the quality of dose delivery. The influence of modulation restriction tool on the plan quality and sensitivity is also investigated. Materials: Twelve clinical implants for HDR Brachytherapy of prostate cancer have been selected out of the clinical routine. The range of the prostate volumes was 26-101 cm3. Due to the fact that the implanted needles are fixed on the template, the most probable error should be a systematic shi

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37

Katsilieri, Zaira Christiana. "Radiobiological models based evaluation of the consequences of possible changes in the implant geometry and anatomy in the HDR erachytherapy of the prostate cancer." Thesis, 2009. http://nemertes.lis.upatras.gr/jspui/handle/10889/2778.

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The purpose of this work is to investigate the influence of possible patient movement and anatomy alteration on the quality of delivered prostate US based HDR-brachytherapy. The effect of patient movement and anatomy change (after the needle implantation and 3D image set acquisition) on catheter and organ dislocation and the consequences that this generated on the DVHs, conformity index and on radiobiological parameters. Materials and methods: This work is based on 3D image sets and treatment plans of 48 patients obtained right after the needle implantation (clinical plan is based on this 3D

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38

Scharnberg, Eike Katrin. "HDR/PDR Brachytherapie als sinnvolle Behandlungsmöglichkeit bei rezidivierenden Kopf-Hals-Malignomen." 2006. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015470540&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Heydemann-Obradovic, Antonela [Verfasser]. "Tumorkontrolle und Spätfolgen nach alleiniger vaginaler HDR-Brachytherapie in der adjuvanten Behandlung des operierten Endometriumkarzinoms / Antonela Heydemann-Obradovic." 2008. http://d-nb.info/990295753/34.

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40

Gottschling, Birgit. "Brachytherapie (HDR-Iridium 192) bei Kopf-Hals-Tumoren : Indikation, Durchführung und Ergebnisse bei 131 Patienten in der Zeit von 1993 bis 2001 /." 2006. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=014967964&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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41

Anagnostopoulos, Georgios [Verfasser]. "Untersuchung des Einflusses der Patientenkörperanatomie auf die Dosimetrie und Entwicklung eines analytischen Dosisberechnungsmodells für die 192-Ir-HDR-Brachytherapie / vorgelegt von Georgios Anagnostopoulos." 2006. http://d-nb.info/978709853/34.

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