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Journal articles on the topic 'Health aspects of Selenium'
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Brenneisen, Peter, Holger Steinbrenner, and Helmut Sies. "Selenium, oxidative stress, and health aspects." Molecular Aspects of Medicine 26, no. 4-5 (August 2005): 256–67. http://dx.doi.org/10.1016/j.mam.2005.07.004.
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Heninger, I., M. Potin-gautier, M. Astruc, D. Snidaro, V. Vignier, and J. Manem. "Selenium in Sewage Sludge; General Aspects and Analytical Challenge." International Journal of Environmental Analytical Chemistry 67, no. 1-4 (June 1997): 1–13. http://dx.doi.org/10.1080/03067319708031389.
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Garousi, Farzaneh. "The toxicity of different selenium forms and compounds – Review." Acta Agraria Debreceniensis, no. 64 (March 5, 2015): 33–38. http://dx.doi.org/10.34101/actaagrar/64/1859.
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Selenium (Se) is an unusual metalloid of considerable interest from both a toxicological and a nutritional perspective, with a very narrow safe range of intake. Although there are many reports about its detoxification properties, toxicity aspects of it have also been tracked for several decades. Lots of studies demonstrated that low Se is an efficacious avail whereas high Se can induce toxicity and the significant toxicity of selenium emphasizes the need to assess the health risk of various selenocompounds as nutritional supplements. The toxicity of different forms and compounds of selenium is also summarized in this review.
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In, Shian. "Trace Elements and Human Health with Emphasis in Those Aspects Peculair to Selenium." Japanese Journal of Nutrition and Dietetics 50, no. 5 (1992): 253–64. http://dx.doi.org/10.5264/eiyogakuzashi.50.253.
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Kumari, Mannu, and Aparajita Gupta. "Cultivation of oyster mushroom to combat pandemics: medicinal and social aspects." Environment Conservation Journal 23, no. 3 (October 19, 2022): 267–72. http://dx.doi.org/10.36953/ecj.13552398.
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Mushrooms are the spore bearings fruiting bodies that have been used by human being since ancient times for good health. Mushroom is the choicest food of nutrition because it provides important nutrients like proteins, selenium, potassium, riboflavin, Niacin, Vitamin D and more. Oyster mushroom are known for their health benefits. Oyster mushroom protect the heart against cardiovascular diseases, helps in lowering the blood pressure, regulate the cholesterol level, improve immune health and have anti cancer, anti inflammatory and other properties. , Cultivation of oyster mushroom on waste straw not only solve the pollution problem but also improves the economic conditions of farmers.
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FARKHUTDINOV, ISKHAK, LEYLA FARKHUTDINOVA, ANASTASIYA ZLOBINA, ANVAR FARKHUTDINOV, IOSIF VOLFSON, and IRINA MATVEENKO. "HISTORICAL ASPECTS OF MEDICAL GEOLOGY." Earth Sciences History 39, no. 1 (January 1, 2020): 172–83. http://dx.doi.org/10.17704/1944-6187-39.1.172.
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The article examines the relationship between geology and human health from antiquity to today. The doctrine that man is a reflection of the universe was widespread in antiquity. In the Renaissance, the Swiss alchemist, physician and philosopher Paracelsus proclaimed the principle: “Everything is poison, everything is medicine; both depend on the dose”. Until the twentieth century, the role of microelements was identified in the development of only two diseases—hypoferric anemia and endemic goiter. The development of atomic-emission spectroscopy in the 1920s permitted the analysis of elements with exceedingly low concentrations in the environments being studied. Application of this analytical technique made it possible to measure the microelemental composition of soils, plants, animal tissues, and other matter, resulting in important scientific discoveries. Then information was collected on the vital necessity of microelements that previously had been considered as toxic to living organisms. The explanation of different diseases caused by deficiency or excess of different elements was made—‘Bush disease’ among New Zealand cattle by the low content of cobalt in rocks, ataxia of lambs in some regions of Western Australia caused by copper deficiency, osteomalacia in a region of Norway caused by phosphorus deficiency in rocks, ‘white muscle disease’—cardiac muscle dystrophy caused by selenium deficiency, Keshan disease or endemic cardiomyopathy caused by selenium deficiency in soils and other. With the increasing interest in medico-geological research there was a need to unite scientists from different countries. In 2004 the International Medical Geology Association (IMGA) was established. Its aim is to promote awareness concerning this issue among geoscientists, medical specialists, and the public at large. Medical geology is a relatively new scientific field that studies the influence of geological factors on health. The obtained results testify to the prospects of scientific research at the junction of medicine, geology, ecology, and the expediency of further in-depth study of the biological role of geological factors.
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Gliga, Maximilian Cosma, Ionela Maria Pascanu, Camelia Gliga, Ancuta Elena Zahan, and Iulian Merlan. "A Prospective Study about the Influence of Selenium Based Supplements on the Autoimmune Process Evolution and the Health-Related Quality of Life in Patients with Chronic Autoimmune Thyroiditis." Acta Medica Marisiensis 65, no. 3 (September 1, 2019): 97–102. http://dx.doi.org/10.2478/amma-2019-0009.
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AbstractObjective: The purpose of this study was to investigate the benefits of two different Selenium based supplements on patients with chronic autoimmune thyroiditis.Methods: We conducted a prospective study on 50 patients with chronic autoimmune thyroiditis, who were divided into three different treatment groups, one group taking Selenium 100 μg, one Procor T (a combination of Selenium 100 μg and other elements like copper, Zinc and Q10 Conenzyme) and one control group taking Placebo pills. We measured on two follow up visits the antibody levels (anti-thyroidperoxidase- TPO Ab) and offered each patient a standardised questionnaire regarding the thyroid-related quality of life (THYPROro).Results: At the 6 months follow up visit there was a statistically significant decrease in the antibody levels for each treatment group compared to the base levels. The THYPROro questionnaire scores showed an improvement in most aspects regarding the quality of life as well, but there was no significant difference between the placebo and the treated groups in the magnitude of this improvement.Conclusions: Based on our results, we could not identify a certain benefit in improving quality of life with the supplementation of Selenium, as the improvements were at a similar level for the patients who took Placebo pills. Further studies with more patients, as well as taking the Selenium defficiency in consideration (by measuring the basal serum level of Selenium for each patient) would be required to find the target group of patients who could have most benefits of Selenium-based supplementation.
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Schomburg, Lutz. "Selenium Deficiency in COVID-19—A Possible Long-Lasting Toxic Relationship." Nutrients 14, no. 2 (January 11, 2022): 283. http://dx.doi.org/10.3390/nu14020283.
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In the last two years, there has been a surge in the number of publications on the trace element selenium (Se) and selenocysteine-containing selenoproteins in human health, largely due to the pandemic and the multiple roles that this micronutrient and Se-dependent selenoproteins play in various aspects of the disease [...]
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Lapčík, O. "Endocrinological aspects of dietary habits." Czech Journal of Food Sciences 22, No. 1 (November 16, 2011): 29–38. http://dx.doi.org/10.17221/3404-cjfs.
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Dietary habits reflect both the recent economic possibilities and the cultural history of individual human populations. They may influence endocrine systems and thus affect the health of the respective populations in several manners: (1) People consuming exclusively local products may lack certain micronutrients. This is important especially in areas with low levels of iodine and/or selenium in the environment. Thyroid gland insufficiency resulting from the iodine deficiency was widespread in many areas of Central Europe until the introduction of iodine supplementation in the second half of 20<sup><sup>th</sup> </sup>century. Iodine deficiency is still a serious problem in many areas of Africa and Asia. (2) Numerous cultural plants contain compounds able to influence important metabolic pathways. Iodine deficiency is usually worsened by thyroidal peroxidase inhibitors, so-called goitrogens. Phenolic and terpenoid compounds may interfere in the metabolism of steroid hormones. Glycyrrhetinic acid from licorice is a potent inhibitor of 11-beta-hydroxysteroid dehydrogenase. Isoflavonoids from legumes (e.g. genistein and daidzein) and their metabolites (e.g. equol) were found to inhibit the following enzymes: aromatase, 5alfa-reductase, 7alfa-hydroxylase, 3beta-hydroxysteroid and 17beta-hydroxysteroid dehydrogenases, etc. Isoflavonoid sulphates influence local availability of steroids by inhibiting sterol sulphatases. (3) Plant-derived compounds are able to interact with nuclear receptors and act either as hormone agonists or as antagonists. Recently, the attention has been paid namely to the phenolic substances interacting with oestrogen receptors so-called phyto-oestrogens.
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Oehlenschläger, Jörg. "Seafood: Nutritional Benefits and Risk Aspects." International Journal for Vitamin and Nutrition Research 82, no. 3 (June 1, 2012): 168–76. http://dx.doi.org/10.1024/0300-9831/a000108.
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Seafood, such as fish, crustacean and molluscan shellfish, and echinoderms, provides in the edible part (e. g., filet, abdominal muscle) many nutritional components beneficial for the human diet like n-3 polyunsaturated long chain fatty acids (PUFAs), namely eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), essential elements such as selenium and iodine, high potassium and low sodium concentrations, and the vitamins D, A, E, and B12, as well as taurine (2-aminoethanesulfonic acid) among others. Its protein is highly digestible due to low connective tissue content, and cholesterol content is also low in fish. Lean fish species are extremely low in fat content (<1 %), while fatty species are extremely rich in PUFAs. However, being subject to environmental influences from its habitat, seafood also entails water-borne health risks such as organic pollutants, toxins, parasites, and heavy metals. Nevertheless, the vast majority of experimental and epidemiological studies have proven that the benefits of fish intake exceed the potential risks even for vulnerable consumer groups.
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Yadav, Sapna, Sinky Sharma, Kamal Dutt Sharma, Pooja Dhansu, Suman Devi, Kumar Preet, Pooja Ahlawat, et al. "Selenium Mediated Alterations in Physiology of Wheat under Different Soil Moisture Levels." Sustainability 15, no. 3 (January 17, 2023): 1771. http://dx.doi.org/10.3390/su15031771.
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Soil moisture stress is one of the most serious aspects of climate change. Selenium (Se) is regarded as an essential element for animal health and has been demonstrated to protect plants from a number of abiotic challenges; however, our knowledge of Se-regulated mechanisms for enhancing crop yield is limited. We investigated the effects of exogenous Se supplementation on physiological processes that may impact wheat productivity during soil moisture stress. The plants were grown in plastic containers under screen-house conditions. The experiment was laid out in CRD consisting of three soil moisture regimes, i.e., control (soil moisture content of 12.5 ± 0.05%), moderate (soil moisture content of 8.5 ± 0.05%), and severe moisture stress (soil moisture content of 4.5 ± 0.05%). Selenium was supplied using sodium selenite (Na2SeO3) through soil application before sowing (10 ppm) and foliar application (20 ppm and 40 ppm) at two different growth stages. The foliar spray of Se was applied at the vegetative stage (70 days after planting) and was repeated 3 weeks later, whereas the control consisted of a water spray. The water status, photosynthetic efficiency, and yield were significantly decreased due to the soil’s moisture stress. The exogenous Se application of 40 ppm resulted in decreased negative leaf water potential and improved relative water contents, photosynthetic rate, transpiration rate, and stomatal conductance in comparison to the control (without selenium) under water shortage conditions except the plants treated with soil application of selenium under severe moisture stress at 70 DAS. Subsequently, Se-regulated mechanisms improved 100 seed weight, biological yield, and seed yield per plant. We suggest that Se foliar spray (40 ppm) is a practical and affordable strategy to increase wheat output in arid and semi-arid regions of the world that are experiencing severe water shortages.
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Conway, Eadaoin, Torres Sweeney, Alison Dowley, Stafford Vigors, Marion Ryan, Supriya Yadav, Jude Wilson, and John V. O’Doherty. "Selenium-Enriched Mushroom Powder Enhances Intestinal Health and Growth Performance in the Absence of Zinc Oxide in Post-Weaned Pig Diets." Animals 12, no. 12 (June 9, 2022): 1503. http://dx.doi.org/10.3390/ani12121503.
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This study was conducted to examine the effects of varying selenium (Se) inclusion levels, in the form of Se-enriched mushroom powder (SeMP) and selenite, on post-weaning growth performance (Period 1; day 1–21), intestinal health and antioxidant capacity (Period 2; day 21–39). Weaned pigs were blocked according to live weight, sex and litter of origin and randomly assigned to the following experimental groups: basal (basal + selenite (0.3 ppm Se)); ZnO (basal + ZnO + selenite (0.3 ppm Se)); 0.15 SeMP (basal + SeMP (0.15 ppm Se)); 0.3 SeMP (basal + SeMP (0.3 ppm Se)) and 0.6 SeMP/Sel (basal + SeMP (0.3 ppm Se) + selenite (Sel) (0.3 ppm Se)) with eight replicates/experimental group. After 21 days, the ZnO experimental group was removed from the experiment and the remaining pigs continued on their respective diet until day 39 post-weaning (Period 2). In Period 1, 0.15 SeMP supplementation reduced (p < 0.05) average daily gain (ADG), average daily feed intake (ADFI) and day 21 body weight, and increased (p < 0.05) faecal scores compared to the ZnO group. Supplementation with 0.3 SeMP and 0.6 SeMP/Sel during Period 1 resulted in similar (p > 0.05) ADG, ADFI, gain-to-feed ratio (G:F) and body weight compared to the ZnO group. However, 0.6 SeMP/Sel supplementation increased (p < 0.05) faecal scores compared to the ZnO group. In Period 2, 0.6 SeMP/Sel increased (p < 0.05) ADG, feed efficiency and day 39 body weight compared to the basal group. Supplementation with Se-enriched mushroom powder, at all inclusion levels, increased (p < 0.05) the abundance of Prevotellaceae and Prevotella, decreased (p < 0.05) the abundance of Sporobacter and increased (p < 0.05) the expression of SELENOP in the jejunum compared to the basal group. Lactobacillaceae and Lactobacillus was increased (p < 0.05) in 0.15 SeMP and 0.3 SeMP pigs compared to the basal group. Selenium deposition in muscle and liver tissue increased (p < 0.001) as a function of inclusion level while pigs supplemented with 0.3 ppm organic Se (0.3 SeMP) had an increase (p < 0.05) in total Se in the muscle compared to pigs supplemented with 0.3 ppm inorganic Se (basal). In conclusion, 0.3 SeMP supplementation led to positive effects on faecal scores and had similar pig performance compared to ZnO in Period 1, while the addition of 0.3 ppm selenite to 0.3 SeMP (0.6 SeMP/Sel) in Period 2 led to enhanced pig performance and aspects of gastrointestinal health.
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Pinheiro, Maria da Conceição Nascimento, José Luiz Martins do Nascimento, Luiz Carlos de Lima Silveira, João Batista Teixeira da Rocha, and Michael Aschner. "Mercury and Selenium – A Review on Aspects Related to the Health of Human Populations in the Amazon." Environmental Bioindicators 4, no. 3 (August 31, 2009): 222–45. http://dx.doi.org/10.1080/15555270903143440.
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Bhattacharya, Preeti Tomar, Satya Ranjan Misra, and Mohsina Hussain. "Nutritional Aspects of Essential Trace Elements in Oral Health and Disease: An Extensive Review." Scientifica 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/5464373.
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Human body requires certain essential elements in small quantities and their absence or excess may result in severe malfunctioning of the body and even death in extreme cases because these essential trace elements directly influence the metabolic and physiologic processes of the organism. Rapid urbanization and economic development have resulted in drastic changes in diets with developing preference towards refined diet and nutritionally deprived junk food. Poor nutrition can lead to reduced immunity, augmented vulnerability to various oral and systemic diseases, impaired physical and mental growth, and reduced efficiency. Diet and nutrition affect oral health in a variety of ways with influence on craniofacial development and growth and maintenance of dental and oral soft tissues. Oral potentially malignant disorders (OPMD) are treated with antioxidants containing essential trace elements like selenium but even increased dietary intake of trace elements like copper could lead to oral submucous fibrosis. The deficiency or excess of other trace elements like iodine, iron, zinc, and so forth has a profound effect on the body and such conditions are often diagnosed through their early oral manifestations. This review appraises the biological functions of significant trace elements and their role in preservation of oral health and progression of various oral diseases.
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Skrypnik, Liubov, Pavel Feduraev, Anton Golovin, Pavel Maslennikov, Tatiana Styran, Maria Antipina, Anastasiia Riabova, and Dmitriy Katserov. "The Integral Boosting Effect of Selenium on the Secondary Metabolism of Higher Plants." Plants 11, no. 24 (December 8, 2022): 3432. http://dx.doi.org/10.3390/plants11243432.
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Selenium is a micronutrient with a wide range of functions in animals, including humans, and in microorganisms such as microalgae. However, its role in plant metabolism remains ambiguous. Recent studies of Se supplementation showed that not only does it increase the content of the element itself, but also affects the accumulation of secondary metabolites in plants. The purpose of this review is to analyze and summarize the available data on the place of selenium in the secondary metabolism of plants and its effect on the accumulation of some plant metabolites (S- and N-containing secondary metabolites, terpenes, and phenolic compounds). In addition, possible molecular mechanisms and metabolic pathways underlying these effects are discussed. It should be noted that available data on the effect of Se on the accumulation of secondary metabolites are inconsistent and contradictory. According to some studies, selenium has a positive effect on the accumulation of certain metabolites, while other similar studies show a negative effect or no effect at all. The following aspects were identified as possible ways of regulating plant secondary metabolism by Se-supplementation: changes occurring in primary S/N metabolism, hormonal regulation, redox metabolism, as well as at the transcriptomic level of secondary metabolite biosynthesis. In all likelihood, the confusion in the results can be explained by other, more complex regulatory mechanisms in which selenium is involved and which affect the production of metabolites. Further study on the involvement of various forms of selenium in metabolic and signaling pathways is crucial for a deeper understanding of its role in growth, development, and health of plants, as well as the regulatory mechanisms behind them.
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Buturi, Camila Vanessa, Rosario Paolo Mauro, Vincenzo Fogliano, Cherubino Leonardi, and Francesco Giuffrida. "Mineral Biofortification of Vegetables as a Tool to Improve Human Diet." Foods 10, no. 2 (January 21, 2021): 223. http://dx.doi.org/10.3390/foods10020223.
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Vegetables represent pillars of good nutrition since they provide important phytochemicals such as fiber, vitamins, antioxidants, as well as minerals. Biofortification proposes a promising strategy to increase the content of specific compounds. As minerals have important functionalities in the human metabolism, the possibility of enriching fresh consumed products, such as many vegetables, adopting specific agronomic approaches, has been considered. This review discusses the most recent findings on agronomic biofortification of vegetables, aimed at increasing in the edible portions the content of important minerals, such as calcium (Ca), magnesium (Mg), iodine (I), zinc (Zn), selenium (Se), iron (Fe), copper (Cu), and silicon (Si). The focus was on selenium and iodine biofortification thus far, while for the other mineral elements, aspects related to vegetable typology, genotypes, chemical form, and application protocols are far from being well defined. Even if agronomic fortification is considered an easy to apply technique, the approach is complex considering several interactions occurring at crop level, as well as the bioavailability of different minerals for the consumer. Considering the latter, only few studies examined in a broad approach both the definition of biofortification protocols and the quantification of bioavailable fraction of the element.
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Gore, Fiona, John Fawell, and Jamie Bartram. "Too much or too little? A review of the conundrum of selenium." Journal of Water and Health 8, no. 3 (December 4, 2009): 405–16. http://dx.doi.org/10.2166/wh.2009.060.
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Chemical elements such as selenium, fluoride, iron, calcium and magnesium are essential to the human being, although some are toxic when absorbed in high doses. In this paper, the risks associated with insufficient and excessive intake of selenium in the diet are reviewed, focusing on drinking water. Two different approaches are used to derive recommended nutrient intakes (RNI) for adequate nutritional status and guideline values to prevent excessive exposure. The former is based on the daily intake which meets the nutrient requirements of 97.5% of the population. The latter is a value derivation based on an assumed daily per capita consumption at the individual level, a conservative approach used where there is any uncertainty and is related to a negligible risk to health at population level across life stages. There is an increasing need to develop a conceptual framework bringing together aspects of toxicity and essentiality especially for elements apparently exhibiting narrow or overlapping ranges between essentiality and toxicity and to provide guidance on the nature and severity of risks in order to better protect human. While there are a number of frameworks available, these generally only consider food. There is a need to include water, which can be a significant source in some circumstances.
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ROOKE, J. A., J. J. ROBINSON, and J. R. ARTHUR. "Effects of vitamin E and selenium on the performance and immune status of ewes and lambs." Journal of Agricultural Science 142, no. 3 (June 2004): 253–62. http://dx.doi.org/10.1017/s0021859604004368.
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Inclusion in the diet of concentrations of vitamin E and selenium (Se) above requirement is associated with variable improvements in animal performance and immune function. At the cellular and molecular level, research in the last decade has produced a clearer understanding of the mechanisms underlying the multiple functions of vitamin E and Se and it is apparent that these functions extend beyond antioxidant protection. This paper reviews recent research relating to the functionality of vitamin E and Se in relation to the ewe and her lambs and attempts to relate this understanding to the whole animal level. Important aspects of this improved understanding are descriptions of three groups of seleno-proteins and the appreciation that there is a hierarchy in both the distribution of selenium between tissues and in the synthesis of different enzymes within tissues. In addition, there is diversity in the effects of vitamin E and Se derivatives on immune cell function. Given this heterogeneity in function it is not surprising that published responses for the production and health of ewes and lambs to supplementary vitamin E and selenium are variable and not always positive. Coupled with information on factors influencing variability in supply of vitamin E and Se from fresh and conserved forages and concentrate supplements, this review highlights the need for greater awareness of the importance of adequate supplementation of ewe and lamb diets with vitamin E and Se.
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Asín, Javier, Gustavo A. Ramírez, Mauricio A. Navarro, Akinyi C. Nyaoke, Eileen E. Henderson, Fábio S. Mendonça, Jéssica Molín, and Francisco A. Uzal. "Nutritional Wasting Disorders in Sheep." Animals 11, no. 2 (February 15, 2021): 501. http://dx.doi.org/10.3390/ani11020501.
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The different ovine production and breeding systems share the cornerstone of keeping a good body condition to ensure adequate productivity. Several infectious and parasitic disorders have detrimental effects on weight gains and may lead to emaciation. Flock health management procedures are aimed to prevent such conditions. Nutritional management is equally important to guarantee adequate body condition. Persistent bouts of low ruminal pH due to excess concentrate in the diet may lead to subacute ruminal acidosis. Pre-stomach motility disorders may also lead to ill-thrift and emaciation. An adequate mineral supplementation is key to prevent the effects of copper, selenium, and other micronutrients deprivation, which may include, among others, loss of condition. This review elaborates on the clinico-pathologic, diagnostic, and therapeutic aspects of some of these conditions, and highlights the necessity of considering them as contributors to states of wasting in sheep flocks.
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Sies, Helmut. "Findings in redox biology: From H2O2 to oxidative stress." Journal of Biological Chemistry 295, no. 39 (September 25, 2020): 13458–73. http://dx.doi.org/10.1074/jbc.x120.015651.
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My interest in biological chemistry proceeded from enzymology in vitro to the study of physiological chemistry in vivo. Investigating biological redox reactions, I identified hydrogen peroxide (H2O2) as a normal constituent of aerobic life in eukaryotic cells. This finding led to developments that recognized the essential role of H2O2 in metabolic redox control. Further research included studies on GSH, toxicological aspects (the concept of “redox cycling”), biochemical pharmacology (ebselen), nutritional biochemistry and micronutrients (selenium, carotenoids, flavonoids), and the concept of “oxidative stress.” Today, we recognize that oxidative stress is two-sided. It has its positive side in physiology and health in redox signaling, “oxidative eustress,” whereas at higher intensity, there is damage to biomolecules with potentially deleterious outcome in pathophysiology and disease, “oxidative distress.” Reflecting on these developments, it is gratifying to witness the enormous progress in redox biology brought about by the science community in recent years.
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Abdelrahman, Mutassim M., Ibrahim A. Alhidary, Riyadh S. Aljumaah, and Bernard Faye. "Blood Trace Element Status in Camels: A Review." Animals 12, no. 16 (August 18, 2022): 2116. http://dx.doi.org/10.3390/ani12162116.
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Trace minerals play an important role in animal health and productivity. They are involved also in many physiological activities, and their deficiency causes a variety of pathological problems and metabolic defects, reducing consequently the animal productivity. The demand for animal products in semi-arid areas is rapidly increasing, and the supply is still below the required level, partially due to low animal productivity. Camels (Camelus dromedarius and Camelus bactrianus) are considered one of the main sources of healthy, high-quality meat and milk for human consumption within most of the countries in the semi-arid regions. Despite their efficient adaptation to their environment, camels can suffer from the growth retardation of newborns, low feed efficiency, anemia, poor fertility, poor reproduction and many other metabolic disorders. It is well known that trace mineral deficiencies and trace mineral toxicities can influence camels’ production and reproductive efficiency, as well as many aspects of their growth and metabolism. Evaluating the trace minerals status of camels and their variability is an obvious step toward improving camels’ productivity and health. Thus, the present article reviews the data regarding the status of trace minerals (copper, zinc, iron, selenium, manganese, cobalt, iodine, fluorine, molybdenum, sulfur, bromide and nickel) in camel blood and their physiological variability, with a focus on their deficiency and toxicity effects.
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Toninello, Paolo, Alvise Montanari, Franco Bassetto, Vincenzo Vindigni, and Antonio Paoli. "Nutritional Support for Bariatric Surgery Patients: The Skin beyond the Fat." Nutrients 13, no. 5 (May 6, 2021): 1565. http://dx.doi.org/10.3390/nu13051565.
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Body contouring surgery after the massive weight loss due to bariatric surgery deals with different kinds of complications. The aim of this review is to analyze the role that some nutrients may play in tissue healing after surgery, thus helping plastic surgeons to improve the aesthetic and health outcomes in massive weight loss patients under a multidisciplinary approach. As a matter of fact, preoperative nutritional deficiencies have been shown for vitamins and minerals in a large percentage of post-bariatric patients. Preoperative deficiencies mainly concern iron, zinc, selenium, and vitamins (both fat-soluble and water-soluble), but also total protein. During the postoperative period, these problems may increase because of the patients’ very low intake of vitamins and minerals after bariatric surgery (below 50% of the recommended dietary allowance) and the patients’ low compliance with the suggested multivitamin supplementation (approximately 60%). In the postoperative period, more attention should be given to nutritional aspects in regard to the length of absorptive area and the percentage of weight loss.
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KOENHEMSİ, LORA, FATMA ATEŞ ALKAN, GİULİA MORGANTİ, BORA Ü. BARUTÇU, and ERMAN M. OR. "Evaluation of trace elements in equine piroplasmosis." Medycyna Weterynaryjna 75, no. 02 (2019): 6230–2019. http://dx.doi.org/10.21521/mw.6230.
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Equine piroplasmosis (EP) is a tick-borne disease caused by Babesia caballi and Theileria equi, which causes a significant economic loss. The aim of this study was to determine the disease-related changes of serum trace elements that play an important role in the immune system. Our study was conducted on 20 horses with piroplasmosis and 20 healthy horses. It was performed to evaluate some of the serum trace element levels (chromium (Cr), copper (Cu), iron (Fe), magnesium (Mg) manganese (Mn), selenium (Se), zinc (Zn), arsenic (As), boron (B), and nickel (Ni)) in equine piroplasmosis. The elements were analyzed in serum using ICP-OES. Infected horses had significantly higher serum Mg and Mn levels. In conclusion, changes of serum trace elements in infected horses can provide valuable information about pathophysiological aspects and they are also good indicators for diagnosis, prognosis and treatment evaluation. Much more scientific research is required to evaluate the trace elements related to equine piroplasmosis.
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Krupp, Eva M. "Preface." Pure and Applied Chemistry 84, no. 2 (January 1, 2012): iv. http://dx.doi.org/10.1351/pac20128402iv.
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Trace elements are a vital ingredient in our food, which directly relates to our health and well-being. The study of health effects related to the abundance or deficiency of trace elements that we are exposed to in our daily life is of prime importance in order to understand mechanisms and interactions of those elements within the human body. Trace elements taken up with food may exert toxic actions (e.g., in the case of arsenic or mercury), others are essential and a deficiency in these trace elements (e.g., iron, selenium, zinc, or iodine) can have drastic health effects and cause diseases.Therefore, toxic as well as essential aspects of trace elements must be studied and understood, so that regulating or governing bodies may advise on permissible levels for toxic elements, or recommend daily doses for the uptake of essential elements.The 4th International Conference on Trace Elements in Food (TEF-4) addressed a range of issues related to the health effects of trace elements and provided a podium for researchers from different scientific backgrounds: analytical chemists, toxicologists, nutritionists, environmental scientists, and members of health authorities came together to present and discuss recent advances and findings.The conference was held from 19 to 22 June 2011 in the King’s Conference Centre at the University of Aberdeen in Scotland (UK), with Prof. John Beattie (Rowett Institute for Nutrition and Health/University of Aberdeen) and Prof. Jörg Feldmann (University of Aberdeen) acting as Conference Chairs. TEF-4 attracted 150 delegates from 39 countries; 38 oral lectures were presented, 13 of which were given by internationally renowned invited speakers. The scientific program also included a poster exhibition with 108 papers and was completed by 9 exhibiting sponsors, including major analytical instrument manufacturers and representatives of reference material laboratories and government institutes.The scientific program comprised four larger themes, each of which was represented by invited speakers and further oral presentations on the following topics:- source and transfer of trace elements into food and feed- trace elements in nutrition and health- toxicology and risk assessment of trace elements in food- analytical advances in trace elements in foodSpecial attention was paid to selenium as an essential element, and a variety of talks explored the toxic actions of arsenic in different foodstuffs and in epidemiology, completed with topics on mercury, zinc, manganese, iodine, cerium, and other trace metals.The collection of papers in this issue of Pure and Applied Chemistry is a representation of the main topics covered in the lectures held during TEF-4, providing an overview of recent advances in research techniques and findings. We hope that it proves a useful source of new and exciting results, leading the way into the future of food analysis, and that fruitful interdisciplinary collaboration will enhance the impact of fundamental and applied research.Eva M. KruppConference Editor
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Levitsky, I. V., and N. M. Kinash. "MODERN ASPECTS OF THE ETIOPATHOGENESIS OF ISTMIC-CERVICAL INSUFFICIENCY." Art of Medicine 22, no. 2 (July 20, 2022): 136–41. http://dx.doi.org/10.21802/artm.2022.2.22.136.
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Isthmic-cervical insufficiency (ICI), which results in the failure of the circular muscles of the internal os, isthmus and cervix of the uterus is important in the pathogenesis of preterm birth. The existing types are anatomical, functional and congenital ICI. ICI is a pathological condition of the cervix and the isthmus, in which they are unable to withstand the intrauterine pressure and keep a fertilized egg in the uterine cavity until birth. ICI is a serious complication of pregnancy. Genetic, hormonal, inflammatory-infectious, immunological, traumatic factors play a role in the occurrence of ICI. The aim of the study is to study the peculiarities of reproductive health and gestational process of pregnant women with ICI, according to the literature. For the study, we analyzed domestic and foreign publications on this topic in professional journals, as well as data from Internet resources. Results of the research show that ICI plays a special role among many causes that lead to preterm termination of pregnancy and premature birth in the II-III trimesters. The properties of the cervix depend on the ratio of connective and muscle tissue. Today, most authors distinguish between congenital, acquired, organic and functional isthmic-cervical insufficiency.Organic (post-traumatic, secondary) ICI occurs due to mechanical damage to the cervix. Functional ICI is the result of a violation of the relationship between the muscular and connective tissues of the cervix, as well as the result of changes in the response of its structural elements to neurohumoral stimuli. Functional ICI most often occurs as a consequence of a violation of the hormonal background of women (ovarian hypofunction, hyperandrogenism). Congenital ICI occurs in malformations of the uterus, genital infantilism. Histological examination of cervical tissue in women with ICI reveals an increase in muscle tissue up to 50%, which leads to early softening of the cervix of the uterus and development of its functional insufficiency. According to Kaufman KP (2021), the role of connective tissue in the development of ICI is confirmed by the fact, that this pathological condition of the cervix is found in women with Marfan syndrome and Ehlers-Danlos syndrome. The role of undifferentiated connective tissue dysplasia (UCTD) as a risk factor for complicated pregnancy, including ICI.Research of Huang J and co-authors (2021) found the presence of nutritional imbalance in patients with UCTD, which was manifested by changes in serum concentrations of magnesium, calcium, zinc, iron, copper, selenium, inorganic phosphorus. The relationship between changes in the microcirculation system, tissue perfusion and cervical condition is currently being actively discussed and confirmed in numerous studies.Fettweis JM (2019) believes that the mechanism of abortion at different stages of gestation is not the same in pregnant women with ICI. At the same time, all pregnant women with ICI at all stages of gestation have increased cytokine levels. However, an important factor in the premature termination of pregnancy in ICI is assigned to the infectious factor. The results of the study of the pathogenetic role of local immune responses in women with habitual miscarriage are often contradictory and dictate the need for further researches.Eventually, isthmic-cervical insufficiency is a multifactorial complication of pregnancy, in which genetic, hormonal, inflammatory-infectious, immunological or traumatic factors play a role.
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Barani, Mahmood, Saman Sargazi, Vahideh Mohammadzadeh, Abbas Rahdar, Sadanand Pandey, Niraj Kumar Jha, Piyush Kumar Gupta, and Vijay Kumar Thakur. "Theranostic Advances of Bionanomaterials against Gestational Diabetes Mellitus: A Preliminary Review." Journal of Functional Biomaterials 12, no. 4 (September 28, 2021): 54. http://dx.doi.org/10.3390/jfb12040054.
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Gestational diabetes mellitus (GDM) is the most frequent complication during pregnancy. This complex disease is characterized by glucose intolerance and consequent hyperglycemia that begins or is first diagnosed in pregnancy, and affects almost 7% of pregnant women. Previous reports have shown that GDM is associated with increased pregnancy complications and might cause abnormal fetal development. At present, treatments are not suitable for the prevention and management of these patients. As an alternative therapeutic opportunity and a leading scientific technique, nanotechnology has helped enlighten the health of these affected women. Theranostic nanomaterials with unique properties and small sizes (at least <100 nm in one of their dimensions) have been recently engineered for clinics and pharmaceutics. Reducing materials to the nanoscale has successfully changed their properties and enabled them to uniquely interact with cell biomolecules. Several biosensing methods have been developed to monitor glucose levels in GDM patients. Moreover, cerium oxide nanoparticles (NPs), selenium NPs, polymeric NPs, and drug-loaded NPs loaded with therapeutic agents have been used for GDM treatment. Still, there are some challenges associated with the detection limits and toxicity of such nanomaterials. This preliminary review covers the aspects from a fast-developing field to generating nanomaterials and their applications in GDM diagnosis and treatment.
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Dokkum, W. Van, R. H. De Vos, TH Muys, and J. A. Wesstra. "Minerals and trace elements in total diets in The Netherlands." British Journal of Nutrition 61, no. 1 (January 1989): 7–15. http://dx.doi.org/10.1079/bjn19890087.
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1. During a period of 2·5 years, every 3 months 221 different food items forming a ‘market basket’ were purchased, prepared and divided into twenty-three food-commodity groups. The ‘market basket’ was based on a study of the dietary intake of 18-year-old male, Dutch adolescents. In the (homogenized) food groups various minerals and trace elements were determined.2. The mean daily amounts of cadmium (21 μg), mercury (0·7 μg), lead (32 μg), tin (0·65 mg), arsenic (38 μg) and bromine (8 mg) in the diet of adolescents, as calculated from the concentrations analysed in the food groups, were all (well) below the Food and Agriculture Organization/World Health Organization acceptable daily intake (ADI) value (Codex Alimentarius Commission, 1984).3. The mean daily amounts of zinc (14 mg) and selenium (72 μg) seemed to be adequate compared with the Dutch recommendations, (Voedingsraad (Dutch Nutrition Council) 1986). The amounts of copper (mean value 1·5 mg/d) and iron (mean value 14 mg/d) in the total diet were marginal. Contents of calcium (1340 mg/d), magnesium (433 mg/d) and iodine (402 μg/d) were all well above the Dutch recommendations for male adolescents. Sodium intake, corresponding to 11 g sodium chloride/d, was higher than advised.4. It is concluded that the amounts of As, Br and toxic heavy metals in Dutch total-diet samples of male adolescents are of little concern as regards health aspects. Among the essential trace elements, Fe and Cu contents seem to be marginal. Some concern regarding the salt content is indicated.
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Cubadda, Francesco. "Preface." Pure and Applied Chemistry 82, no. 2 (January 1, 2010): iv. http://dx.doi.org/10.1351/pac20108202iv.
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Diet is the main source of trace elements, and exposure to dietary trace elements has a direct impact on the health of hundreds of millions worldwide. Insufficient intake of essential trace elements is a global issue. Deficiencies of iron, zinc, iodine, and selenium result in millions of people being affected by various diseases, with very serious consequences in those countries where malnutrition is widespread. On the other hand, the impact of toxic element species such as inorganic arsenic and methylmercury on entire populations has come to the fore again as a priority for both the scientific community and health authorities. The presence of trace elements in feeds, either as contaminants or as nutritional or zootechnical additives, and their transfer across the food chain to humans also raises questions within the scientific community and regulators.Different facets of trace elements, from essentiality to toxicity, were addressed throughout the 3rd International IUPAC Symposium on Trace Elements in Food (TEF-3). The meeting was organized by the Istituto Superiore di Sanità and held on 1-3 April 2009 in Rome, Italy. The objective was to gather experts with different backgrounds to discuss all aspects of trace elements in food in relation to human health, with special emphasis on biological effects of elements. The main topics included essentiality, toxicity, bioaccessibility, bioavailability, speciation, sources and transfer in the food chain, effects of processing, food and feed fortification, supplementation, international legislation and standards, analytical developments, analytical quality assurance and reference materials. In accordance with practice in previous events of this series (Warsaw, 2000, and Brussels, 2004), TEF-3 provided a forum for the exchange of new ideas and experiences in trace element research, and a basis for influencing policy, advisory practice, and risk-management tools to protect public health.Over 200 participants, representing some 40 countries, joined the event. In addition to the 15 invited lectures, delegates from Europe, Asia, Africa, North and South America enriched this edition with 20 oral and about 130 poster contributions. TEF-3 actually resulted in a lively interdisciplinary symposium on current and emerging research and development efforts.Special emphasis was placed on the following topics:- analytical techniques for element speciation studies in food and food supplements- reliability and quality control of analytical data on trace elements in foodstuffs- detection, characterization, and potential health risks of inorganic nanoparticles- arsenic speciation and toxicology- gender differences in susceptibility to toxic trace elements in food- exposure assessment of toxic element species- assessment of risks and benefits of the organic forms of trace elements as feed additives- metabolism of metal(loid)s by intestinal microorganisms- absorption and metabolism of iron, zinc, and other essential elements- use of stable isotopes to study trace mineral metabolism- selenium and iodine speciation and biological effectsAdvancements in the above-mentioned areas were discussed, and special attention was paid to the means in order to prevent adverse health effects on those individuals and populations most vulnerable to trace-element inadequacies, excesses, or imbalances.The following collection of papers based upon authoritative lectures presented at TEF-3 addresses many of the topics discussed during the symposium. Overall, it provides an excellent overview of the state of the art in the area of trace elements in food and sheds light on future challenges and subjects of research.Francesco CubaddaConference Chair
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Mladěnka, Přemysl, Radomír Hrdina, Zuzana Bobrovová, Vladimír Semecký, Jaroslava Vávrová, Magdaléna Holečková, Vladimir Palicka, Yvona Mazurová, and Petr Nachtigal. "Cardiac biomarkers in a model of acute catecholamine cardiotoxicity." Human & Experimental Toxicology 28, no. 10 (October 2009): 631–40. http://dx.doi.org/10.1177/0960327109350665.
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Coronary heart disease and in particular its most serious form — acute myocardial infarction (AMI) — represents the most common cause of mortality in developed countries. Better prognosis may be achieved by understanding the etiopathogenetic mechanisms of AMI. Therefore, a catecholamine model of myocardial injury, which has appeared to be very similar to AMI in human in some aspect, was used. Male Wistar:Han rats were randomly divided into two groups: control group (saline) and isoprenaline group (ISO; synthetic catecholamine, 100 mg.kg— 1 subcutaneously [s.c.]). After 24 hours, functional parameters were measured, biochemical markers in the blood and metals content in the heart tissue were analysed and histological examination was performed. ISO caused marked myocardial injury that was associated with myocardial calcium overload. Close correlation between myocardial impairment (i.e. serum TnT, stroke volume index and wet ventricles weight) and the levels of myocardial calcium was observed. Direct reactive oxygen species (ROS) involvement was documented only by non-significant increase in malonyldialdehyde 24 hours after ISO injury. Moreover, myocardial element analysis revealed no significant changes as for the content of zinc and iron while selenium and copper increased in the ISO group although it reached statistical significance only for the latter.
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Soda, Kenji. "Biochemical Aspects of Selenium Amino Acids and Selenium Peptides." Phosphorus, Sulfur, and Silicon and the Related Elements 67, no. 1-4 (April 1, 1992): 461–72. http://dx.doi.org/10.1080/10426509208045872.
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Zumkley, H. "Clinical aspects of selenium metabolism." Biological Trace Element Research 15, no. 1 (January 1988): 139–46. http://dx.doi.org/10.1007/bf02990132.
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Krivošíková, Alexandra, Ľudmila Nagyová, and Andrej Géci. "Perception of sensory attributes and marketing tools of selected milk brands." Potravinarstvo Slovak Journal of Food Sciences 14 (October 28, 2020): 905–13. http://dx.doi.org/10.5219/1363.
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The research has shown that in the last 5,000 years the human evolution has made the greatest leap in the human history. As a result of these changes, thanks to relatively recent discovery of a specific gene, even adult Europeans can digest milk. In their nutritional guidelines based on the scientific evidence, the official health organizations and institutions recommend drinking milk and eating low-fat dairy products such as yoghurts or cheese. The human body absorbs the necessary amount of calcium in the easiest form from cow's milk. Calcium is the essential element not only for healthy bones and teeth but it is also the important factor for the transmission of nerve impulses, it supports heart activity, helps reduce high blood pressure and "bad" LDL cholesterol levels and alleviate allergic reactions. It has impact on proper blood clotting, affects sperm mobility, helps prevent arthritis or can also contribute to better sleep. Milk is a valuable food not only for calcium content but also for selenium which slows down the aging process and contributes to the protection of the immune system. Acid dairy products prevent the digestive disorders, protect against gastrointestinal infections and improve skin condition. Despite all these positive aspects the consumption of milk, as well as dairy products, has the downward trend in Slovakia. In the last decade, the consumption was at a historical minimum and below the recommended annual dose, which is 91 liters of milk per person. Therefore, the main objective of this research paper was to examine the quality of milk produced by two selected competing companies and identify the various factors affecting consumers´ decision-making process when purchasing milk and dairy products. The attention was concentrated on the sensory attributes (colour, appearance, smell, taste and quality) and marketing tools (brand, packaging, label and price). The primary data were obtained by the questionnaire survey, which was conducted in the Slovak Republic with 284 respondents. For a deeper analysis, the data were evaluated by the statistical methods. Based on the results of the blind testing it was determined that even though the quality of monitored milk is the same, the respondents prefer the sensory attributes of Rajo semi-skimmed milk. When it comes to brand, packaging, label and price Tami semi-skimmed milk also lagged behind.
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Vilms, Elena A., D. V. Turchaninov, O. A. Pasechnik, T. M. Obukhova, V. G. Demchenko, I. A. Sokhoshko, and V. A. Shirinsky. "FEATURES OF THE MICRONUTRIENT COMPOSITION OF THE DIET IN TUBERCULOSIS PATIENTS AFFECTING." Hygiene and sanitation 98, no. 12 (December 15, 2019): 1420–24. http://dx.doi.org/10.18821/0016-9900-2019-98-12-1420-1424.
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Introduction. The status of polyhypovitaminosis accompanying tuberculosis infection being widespread develops both as a result of the disease and side effects of drugs, and because of insufficient food intake. The purpose of the study is to evaluate the micronutrient composition of the diet of tuberculosis patients in the acute stage and healthy people in a comparative aspect. Material and Methods. The method of analyzing the frequency of food consumption assessed the actual nutrition of tuberculosis patients in the acute stage (n = 300) and healthy residents of the region (n = 189). Data on the actual nutrition was collected using a standard questionnaire. In tuberculosis patients, nutrition was evaluated in the month preceding hospitalization. The consumption in the main product groups was calculated, the indices of the vitamin and mineral value of the diet were analyzed. Results. In most patients, the profile of actual consumption was assessed as deficient for several vitamins and trace elements simultaneously. All the examined showed a deficiency in the diet of vitamin D, 80.7 ± 2.3% - vitamin A, 82.0 ± 2.2% - beta-carotene, 90.3 ± 1.7% - folic acid, 63, 7 ± 2.8% of biotin, 45.7 ± 2.8% of ascorbic acid, 49.0 ± 2.8% of vitamin B1, 53.3 ± 2.8% of vitamin PP. Calcium, iodine and selenium are also among the priority ones for the correction of micro- and macro-elements. Differences in the values of actual micronutrient intake were found: in patients with tuberculosis, the levels of beta-carotene, vitamins B2, pantothenic acid, C, D, biotin, choline, calcium, phosphorus are lower; above - consumption of sodium, fluorine, manganese. Differences in micronutrient ration security are determined by unequal amounts of food groups consumed: the nutrition of tuberculosis patients is lower in terms of the content of fruits, dairy, meat products, eggs, and more bread products and drinks. Conclusion. The features of the micronutrient composition of the diet of tuberculosis patients, which determine the need for their correction in the organization of medical nutrition, are established.
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Szöllősi, János, Zoltán Závaczki, and Attila Pál. "Selenium deficiency and infertility. Andrological aspects." Orvosi Hetilap 149, no. 37 (September 1, 2008): 1749–51. http://dx.doi.org/10.1556/oh.2008.28426.
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A szelén abszolút hiánya az emberi szervezetben igen ritkán következik be, de a szuboptimális napi szelénbevitel miatt kialakuló relatív szelénhiány észrevétlenül is kialakulhat. A szelénhiány számos ismert következménye közül a jelen közleményben a szerzők a férfifertilitásra gyakorolt hatásokat emelik ki, összefoglalva a legfontosabb biokémiai, állatkísérletes és humán vonatkozásokat.
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Alaejos, M. Sanz, F. J. Dı́az Romero, and C. Dı́az Romero. "Selenium and cancer: some nutritional aspects." Nutrition 16, no. 5 (May 2000): 376–83. http://dx.doi.org/10.1016/s0899-9007(99)00296-8.
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El Mehdawi, A. F., and E. A. H. Pilon-Smits. "Ecological aspects of plant selenium hyperaccumulation." Plant Biology 14, no. 1 (December 1, 2011): 1–10. http://dx.doi.org/10.1111/j.1438-8677.2011.00535.x.
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SODA, K. "ChemInform Abstract: Biochemical Aspects of Selenium Amino Acids and Selenium Peptides." ChemInform 23, no. 29 (August 21, 2010): no. http://dx.doi.org/10.1002/chin.199229254.
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Mayurnikova, Larisa, Arkadiy Koksharov, Tatyana Krapiva, and Sergey Novoselov. "Food Fortification as a Preventive Factor of Micronutrient Deficiency." Food Processing: Techniques and Technology 50, no. 1 (March 27, 2020): 124–39. http://dx.doi.org/10.21603/2074-9414-2020-1-124-139.
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Introduction. The problem of micronutrient deficiency remains a relevant issue all over the world. However, it is mostly developed countries that practice food fortification. The FAO and the WHO accumulate related experience and summarize it in various documents. Yet some aspects of the problem can be solved on state level. The present research featured micronutrient deficit and preventive measures in several countries taking into account local food traditions. Since 1920, a number of industrially developed northern countries have started developing and implementing various food fortification programs. Similar programs are being introduced in East, Central, and South Africa and Southeast Asia. For 40 years, Russia has been taking various measures to prevent micronutrient deficiency and related diseases.
Results and discussion. The research revealed the social and economic measures of food fortification that were found lacking in these countries. The main problem proved to be iodine, iron, and vitamin A deficiency. However, lack of other micronutrients also remains a burning issue. The present paper gives an overview of iodine, selenium, and iron deficiencies in several countries. The authors proposed several solutions, e.g. food group selection, food additives (mono or premix), various ways of fortification, etc. The article also contains a list of main Russian regulatory documents that control the production and turnover of food fortification. The authors showed advantages of food fortification of mass consumption products, e.g. the low cost of processing, the affordability of enriched products, their availability for different social population, the well-developed regulation standards, the good social effect of food fortification projects, their economic efficiency, etc. Taking into consideration the environmental changes and various geopolitical and economic factors that negatively affect nutrition and population health, the authors recommend to continue evidence-based research in this direction to develop new technologies and food supplements.
Conclusion. The novelty of the research lies in the fact that it reveals priority areas for prospective scientific research in food fortification based on a thorough analysis of the existing experience. From the point of view of practical application, the research offers a deeper understanding of the problem, stresses its relevance, sets goals and objectives of future studies, and offers some ideas for preventive programs.
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Czauderna, M., J. Kowalczyk, and K. A. Krajewska. "Influence of dietary selenium level on the concentration of conjugated linoleic acid isomers, other fatty acids and amino acids in the liver and femoral muscles of rats." Czech Journal of Animal Science 56, No. 2 (February 25, 2011): 81–94. http://dx.doi.org/10.17221/55/2010-cjas.
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The purpose of the present study was to determine the influence of diets containing conjugated linoleic acid isomers (CLAmix) with or without low (<sub>L</sub>Se) or high (<sub>H</sub>Se) concentration of selenised yeast (SeY) on body weight gain (BWG), feed conversion efficiency (FCE), and concentrations of CLA isomers and other fatty acids (FA) in the liver and femoral muscle of rats. The investigation was performed on 48 female rats (Wistar, Hsd Brl Han: WIST), aged 8 weeks with an initial body weight of 195.7 ± 0.8 g. After one week of submaintenance feeding, for 6 weeks the rats were fed ad libitum the Labofeed H diet supplemented with 1.5% CLAmix with or without low (0.2 μg Se/g diet) or high (0.5 μg Se/g diet) concentration of Se as SeY. The diet enriched with <sub>L</sub>Se or <sub>H</sub>Se elevated the BWG of rats compared with the control group, while the <sub>L</sub>Se diet resulted in the most efficient increase in BWG. The diet containing CLAmix, irrespective of the presence of SeY, stimulated the accumulation of Se in the liver and muscles in comparison with the diet enriched with SeY. The addition of SeY to the diet enriched with CLAmix stimulated the accumulation of cis9trans11 (c9t11), t10c12 and cc isomers of CLA in the liver. The diet containing CLAmix and LSe most efficiently increased the concentration of these CLA isomers in muscles. The diets enriched with SeY increased the concentration of essential, endogenous and total amino acids (AA) in the liver, whereas the diets enriched with SeY or CLAmix reduced the concentration of these AA in muscles. The diets enriched with CLAmix and/or SeY decreased the Δ9-desaturase index in the liver and muscles compared with the control group. These diets increased Δ4-, Δ5- and Δ6-desaturase indexes in muscles, but significantly reduced the elongase index compared with the control group. Our study shows that dietary CLAmix increased the concentration of C14:0, C18:0 and the sum of saturated FA (SFA) in the liver, whereas the diets enriched with SeY, irrespective of the presence of CLAmix, slightly reduced the concentration of C14:0, C18:0, and SFA in muscles compared with the control group. The diets containing SeY and/or CLAmix increased the accumulation of arachidonic acid (ArA), linolenic acid (αLNA) and c4c7c10c13c16c19C22:6 in the liver compared with the control rats. Negative effects of dietary SeY and/or CLAmix on the accumulation of αLNA, c5c8c11c14c17C20:5, c7c10c13c16c19C22:5, c4c7c10c13c16c19C22:6, linoleic acid, ArA and c8c11c14C20:3 in muscles were found out. The CLAmix diet increased the Δ4-, Δ5-desaturase and elongase indexes in the liver. It also increased the Δ4-, Δ5- and Δ6-desaturase indexes in muscles, but significantly reduced the elongase index compared with the control group. The finding that the diet with CLAmix and <sub>H</sub>Se fed to rats decreased total FA and most efficiently increased the content of Se and essential AA in muscles is valuable information for nutritionists carrying out research on farm animals to improve the nutritive value of food from the aspect of human health.
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Kim, Y. Y., and D. C. Mahan. "Biological Aspects of Selenium in Farm Animals." Asian-Australasian Journal of Animal Sciences 16, no. 3 (January 1, 2003): 435–44. http://dx.doi.org/10.5713/ajas.2003.435.
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Berger, Stuart B. "CHEMICAL ASPECTS OF SELENIUM AS A PHOTORECEPTOR." Phosphorus and Sulfur and the Related Elements 38, no. 3-4 (August 1988): 375–84. http://dx.doi.org/10.1080/03086648808079732.
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Galmés, Sebastià, Francisca Serra, and Andreu Palou. "Current State of Evidence: Influence of Nutritional and Nutrigenetic Factors on Immunity in the COVID-19 Pandemic Framework." Nutrients 12, no. 9 (September 8, 2020): 2738. http://dx.doi.org/10.3390/nu12092738.
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The pandemic caused by the new coronavirus has caused shock waves in many countries, producing a global health crisis worldwide. Lack of knowledge of the biological mechanisms of viruses, plus the absence of effective treatments against the disease (COVID-19) and/or vaccines have pulled factors that can compromise the proper functioning of the immune system to fight against infectious diseases into the spotlight. The optimal status of specific nutrients is considered crucial to keeping immune components within their normal activity, helping to avoid and overcome infections. Specifically, the European Food Safety Authority (EFSA) evaluated and deems six vitamins (D, A, C, Folate, B6, B12) and four minerals (zinc, iron, copper and selenium) to be essential for the normal functioning of the immune system, due to the scientific evidence collected so far. In this report, an update on the evidence of the contribution of nutritional factors as immune-enhancing aspects, factors that could reduce their bioavailability, and the role of the optimal status of these nutrients within the COVID-19 pandemic context was carried out. First, a non-systematic review of the current state of knowledge regarding the impact of an optimal nutritional status of these nutrients on the proper functioning of the immune system as well as their potential role in COVID-19 prevention/treatment was carried out by searching for available scientific evidence in PubMed and LitCovid databases. Second, a compilation from published sources and an analysis of nutritional data from 10 European countries was performed, and the relationship between country nutritional status and epidemiological COVID-19 data (available in the Worldometers database) was evaluated following an ecological study design. Furthermore, the potential effect of genetics was considered through the selection of genetic variants previously identified in Genome-Wide Association studies (GWAs) as influencing the nutritional status of these 10 considered nutrients. Therefore, access to genetic information in accessible databases (1000genomes, by Ensembl) of individuals from European populations enabled an approximation that countries might present a greater risk of suboptimal status of the nutrients studied. Results from the review approach show the importance of maintaining a correct nutritional status of these 10 nutrients analyzed for the health of the immune system, highlighting the importance of Vitamin D and iron in the context of COVID-19. Besides, the ecological study demonstrates that intake levels of relevant micronutrients—especially Vitamins D, C, B12, and iron—are inversely associated with higher COVID-19 incidence and/or mortality, particularly in populations genetically predisposed to show lower micronutrient status. In conclusion, nutrigenetic data provided by joint assessment of 10 essential nutrients for the functioning of the immune system and of the genetic factors that can limit their bioavailability can be a fundamental tool to help strengthen the immune system of individuals and prepare populations to fight against infectious diseases such as COVID-19.
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CHARATIS, G., G. E. BUSCH, C. L. SHEPARD, P. M. CAMPBELL, and M. D. ROSEN. "HYDRODYNAMIC ASPECTS OF SELENIUM X-RAY LASER TARGETS." Le Journal de Physique Colloques 47, no. C6 (October 1986): C6–89—C6–98. http://dx.doi.org/10.1051/jphyscol:1986612.
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Fordyce, Fiona. "Selenium Geochemistry and Health." AMBIO: A Journal of the Human Environment 36, no. 1 (February 2007): 94–97. http://dx.doi.org/10.1579/0044-7447(2007)36[94:sgah]2.0.co;2.
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Vinciguerra, Manlio. "Selenium improves hippocampus health." Nature Aging 2, no. 3 (March 2022): 188. http://dx.doi.org/10.1038/s43587-022-00202-2.
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Sneddon, Alan A. "Selenium and vascular health." Pure and Applied Chemistry 84, no. 2 (December 31, 2011): 239–48. http://dx.doi.org/10.1351/pac-con-11-09-01.
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Selenium (Se) is an important dietary micronutrient required for sustaining optimal health. Se is incorporated into proteins, many of which are antioxidants that protect the body against oxidative damage. As oxidative damage may contribute to the development of chronic diseases including cardiovascular disease (CVD), Se has been proposed to provide a protective role against this disease. Studies in vitro and in animals continue to provide increasing insight into the role of Se in promoting vascular health and ameliorating CVD. Se within vascular cells limits the adhesion together of such cells, an important early step in the development of vascular disease. Organic forms of Se may also afford vascular cells greater protection against oxidative challenge compared to inorganic forms. Nevertheless, current studies in humans investigating the relationship between Se and CVD have so far proved equivocal; larger randomized trials with different Se exposures in populations spanning the broad physiological Se status are needed to determine the criteria whereby Se may influence CVD outcome within different populations. Further studies are also needed to explore the effects of different Se species and the role of different selenoprotein genotypes in modifying Se status and their resultant impact on cardiovascular function.
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Ørskov, Hans, and Allan Flyvbjerg. "Selenium and human health." Lancet 356, no. 9233 (September 2000): 942–43. http://dx.doi.org/10.1016/s0140-6736(05)73926-x.
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Sher, Leo. "Selenium and human health." Lancet 356, no. 9233 (September 2000): 943. http://dx.doi.org/10.1016/s0140-6736(05)73927-1.
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