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1

Statham, Helen. Detection of fetal abnormality at different gestations: Impact on parents and service implications. Centre for Family Research, University of Cambridge, 2001.

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2

Anderson, Kim. Aboriginal approaches to fetal alcohol syndrome-effects. Edited by Ontario Federation of Indian Friendship Centres. Ontario Federation of Indian Friendship Centres, 2002.

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3

E, Aldred Heather, ed. Pregnancy and birth sourcebook: Basic information about planning for pregnancy, maternal health, fetal growth and development ... Omnigraphics, 1997.

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4

Twilley, Leslie. Predictors of preterm and small-for-gestational-age births in Alberta: Report. Public Health Surveillance & Environmental Health, 2007.

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5

Brian, Dale, ed. In vitro fertilization. 2nd ed. Cambridge University Press, 2000.

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6

Spanish Biochemical Society. Perinatal Biochemical Group. Meeting. Endocrine and biochemical development of the fetus and neonate. Plenum Press, 1990.

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7

Institute of Medicine (U.S.). Committee to Study the Prevention of Low Birthweight. Preventing low birthweight: Summary. National Academy Press, 1985.

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8

Gluckman, Sir Peter, Mark Hanson, Chong Yap Seng, and Anne Bardsley. Conceptual background to healthy growth and development. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780198722700.003.0002.

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This chapter reviews the concepts of developmental plasticity and mismatch, critical periods for exposures, and the emergent science of epigenetics to explain how relatively subtle changes in parental behaviour can affect the outcomes of pregnancy, and why there are echoes of such influences across the whole of life. Contrary to earlier belief that embryonic and fetal development is set by a genetic programme, it is now clear that the fetus responds to cues in the in utero environment and can alter its development and metabolism accordingly. The ‘decisions’ that the developing fetus makes are
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9

Bonnet, Marie-Pierre, and Anne Alice Chantry. Placenta and uteroplacental perfusion. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713333.003.0003.

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The placenta is a complex and changing organ necessary for normal fetal growth and development and for maintenance of a healthy pregnancy. It has three major functions: a protective function of the fetus, an endocrine function, and a metabolic function. The main functional unit of the placenta is the chorionic villous, responsible for the majority of the fetal–maternal exchanges. Migration of trophoblastic cells induces a remodelling of the uterine arteries, with vasodilatated and compliant vessels, unresponsive to maternal vasomotor control. Therefore, any significant change in maternal blood
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10

Quilligan, Edward J., and Norman Kretchmer. Prenatal and Perinatal Biology and Medicine: Physiology and Growth. Harwood Academic Pub, 1987.

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11

Fox, Grenville, Nicholas Hoque, and Timothy Watts. Antenatal care, obstetrics, and fetal medicine. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198703952.003.0001.

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This chapter contains details of methods used for screening and diagnosis of fetal anomalies using antenatal blood tests, ultrasound scanning, chorionic villous sampling, amniocentesis, and fetal blood sampling. There are sections on pre-existing maternal diseases presenting risks to the fetus including maternal diabetes, systemic lupus erythematosus, thrombocytopenia, and neuromuscular disease, as well as those specific to pregnancy—pre-eclampsia, HELLP syndrome, and eclampsia. Intrauterine growth restriction and monitoring is covered in detail. The increased fetal risks of multiple birth due
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12

Gluckman, Sir Peter, Mark Hanson, Chong Yap Seng, and Anne Bardsley. Vitamin B6 (pyridoxine) in pregnancy and breastfeeding. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780198722700.003.0010.

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Vitamin B6 is required for the activity of a large number of enzymes with varied essential functions. Along with other B vitamins, it is involved in the metabolism of homocysteine to cysteine; if this reaction is disrupted, blood homocysteine levels rise, along with increased risks for cardiovascular disease, neuropsychiatric problems, and other adverse effects. Elevated homocysteine in pregnancy it is associated with anaemia, pre-eclampsia, preterm birth, and low birthweight. Vitamin B6 deficiency can also affect fetal brain development, as well as weight gain and linear growth in infancy. Al
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13

Aldred, Heather E. Pregnancy and Birth Sourcebook: Basic Information About Planning for Pregnancy, Maternal Health, Fetal Growth and Development (Health Reference Series). Omnigraphics, 1997.

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14

Kharrazi, Martin. The relationship of health care and demographic factors to secular trends in the rate of intrauterine growth and gestational duration in Westchester County, New York: 1976-1987. 1990.

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15

Mothers, babies, and health in later life. 2nd ed. Churchill Livingstone, 1998.

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16

Gluckman, Sir Peter, Mark Hanson, Chong Yap Seng, and Anne Bardsley. Effects of maternal age on pregnancy outcomes. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780198722700.003.0034.

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Maternal age on both ends of the reproductive spectrum (teenage and 35+) is associated with increased risk of adverse pregnancy outcomes, as compared with the age range from 20–34 years old. Some of the increase in pregnancy complications in older mothers is caused by underlying age-related health issues such as hypertension and diabetes, the prevalence of which increases linearly with age. The risks associated with young maternal age are more related to nutritional deficits and the fact that pregnant adolescents may still be growing themselves. Poor fetal growth often seen in adolescent pregn
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17

Cuezva, Jose M., Ana M. Pascual-Leone, and Mulchand S. Patel. Endocrine and Biochemical Development of the Fetus and Neonate. Springer, 2013.

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18

Cuezva, Jose M., Ana M. Pascual-Leone, and Mulchand S. Patel. Endocrine and Biochemical Development of the Fetus and Neonate. Springer, 2013.

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19

Preventing Low Birthweight. National Academies Press, 1985.

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20

Preventing Low Birthweight. National Academies Press, 1985.

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21

Preventing Low Birthweight: Summary. National Academies Press, 1985.

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22

Preventing Low Birthweight. National Academies Press, 1985.

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23

Preventing low birthweight. National Academy Press, 1985.

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24

Preventing Low Birthweight: Summary. National Academies Press, 1985.

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25

Human Embryology and Developmental Biology. Elsevier - Health Sciences Division, 2018.

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26

Human embryology and developmental biology. Mosby, 1994.

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27

Human Embryology and Developmental Biology: With STUDENT CONSULT Online Access. Elsevier - Health Sciences Division, 2013.

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28

Human embryology and developmental biology. 4th ed. Mosby/Elsevier, 2009.

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29

Human embryogenesis: Methods and protocols. Humana Press, 2009.

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30

Lafond, Julie, and Cathy Vaillancourt. Human Embryogenesis: Methods and Protocols. Humana Press, 2014.

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