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Kaoru, Fueda, and Onuma Kensuke. "Using data science to foster research into factors that impact on road safety." Impact 2019, no. 10 (December 30, 2019): 15–17. http://dx.doi.org/10.21820/23987073.2019.10.15.
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When managers at Aioi Nissay Dowa Insurance Co. Ltd. saw a need to stimulate research into traffic safety using existing big data, they opted to search for suitable partners with the requisite skills and experience to work with them to create an environment to help foster research into factors that impact on road safety. Seeking to leverage this research to help them promote safety on the roads and develop suitable insurance products, they founded a partnership with Shiga University's Graduate School of Data Science - the first such department in Japan - to establish the Japan Safety Society Research Center (JSSRC) to accomplish these goals. Opening in April 2017, the JSSRC has progressively worked towards improving research in this area.
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Ogbo, Felix, Blessing Akombi, Kedir Ahmed, Abdon Rwabilimbo, Akorede Ogbo, Noel Uwaibi, Osita Ezeh, and Kingsley Agho. "Breastfeeding in the Community—How Can Partners/Fathers Help? A Systematic Review." International Journal of Environmental Research and Public Health 17, no. 2 (January 8, 2020): 413. http://dx.doi.org/10.3390/ijerph17020413.
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Support from partners/fathers and families can play a significant role in a mother’s decision to initiate, continue or cease breastfeeding postnatally. This study systematically reviewed published studies to determine the impact of specific types of partner support on breastfeeding initiation, duration and exclusivity. We used the 2015 Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) guidelines for the review. Seven computerized bibliographic databases (Embase, ProQuest Central, Scopus, PsycINFO, Web of Science, MEDLINE/PubMed and CINAHL) were searched. Of a total of 695 articles retrieved from the databases, seven studies met the inclusion criteria and reported on breastfeeding initiation, duration and exclusivity. Four of the seven studies found that partner support in the form of verbal encouragement to new mothers increased breastfeeding duration and exclusivity. Other types of partner supportive actions that led to improved breastfeeding behavior included sensitivity of the partner to the nursing mother’s needs, assistance in preventing and managing breastfeeding difficulties, and helping with household and child care duties. This review showed that specific supportive actions of partners/fathers in the community positively improved breastfeeding practices. To maximise the impact of breastfeeding policies and interventions among new mothers, breastfeeding programmes should consider the involvement of partners/fathers and their specific roles.
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Hillmer, Katrin, Judith Kappesser, and Christiane Hermann. "Pain modulation by your partner: An experimental investigation from a social-affective perspective." PLOS ONE 16, no. 7 (July 22, 2021): e0254069. http://dx.doi.org/10.1371/journal.pone.0254069.
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Background Social context such as the relationship between a person experiencing pain and a caregiver has been shown to affect the experience of pain, yet, results are not consistent. Possibly, differential effects of interpersonal relationships are modulated by affective states expressed by social partners. Viewing partner pictures in experimental designs is not only associated with lowered perceived pain intensity, but also affects neural responses. However, the role of affective modulation is not clear. The present study aimed to systematically examine the pain modulating effects of stimuli varying in affect and social content including personal relevance using subjective report and psychophysiological measures of facial and autonomic activity. Methods Twenty-nine women underwent a tonic heat pain paradigm with simultaneous picture viewing to investigate the influence of their partners’ faces with a neutral facial expression compared to strangers’ happy, angry and neutral facial expressions on pain intensity and accompanying psychophysiological parameters (facial activity: corrugator muscle activity, autonomic activity: skin conductance level, heart rate). In addition to perceived partner support and relationship characteristics, the contribution of the affective value (valence, arousal) of the partner faces to the observed pain modulation was examined. Results Partner and happy faces reduced self-reported pain intensity and corrugator activity, the latter being lowest when viewing partner faces as compared to all other picture categories. As corrugator activity is indexing stimulus unpleasantness and a core feature of the facial pain expression, this physiological pattern matches well with the subjective ratings. Neutral objects, neutral and angry faces had no effect on pain self-report, although angry faces were rated as highly negative. Partner faces also led to increased skin conductance, being an index of motivational activation, and heart rate deceleration, possibly reflecting increased sensory intake. Partner-related pain modulation was primarily related to perceived arousal of the partner’s picture, i.e., the intensity of the activation of approach motivation, and pain-related catastrophizing. Discussion Our results are partially consistent with emotional pain control models, especially regarding the modulatory influence of valence. Within the context of socially adaptive behavior, they particularly underline the social signal value of emotion and attachment figures. Clinically, our results imply that just looking at pictures of one’s partner when undergoing acute painful procedures can have a robust hypoalgesic effect.
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Kovács, Zoltán. "Moral hazard in producer organizations - some experiences of an empirical survey." Applied Studies in Agribusiness and Commerce 10, no. 4-5 (December 31, 2016): 77–83. http://dx.doi.org/10.19041/apstract/2016/4-5/10.
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A wide range of empirical experiences shows that the performance of Hungarian producer organizations (aka TÉSZ) significantly falls behind the activity observed in the developed Western European countries. Regarding this issue, the present study examines how moral hazard - as one of the possible reasons - influences the producers’ activities in cooperative organizations. Information for the research was collected with the help of a questionnaire survey among the members of PaprikaKert TÉSZ Ltd. A statistical path model has been developed for the research, which assumed that - in addition to a direct effect - moral hazard also affects collaborative activity by eroding trust. The statistical model has been tested both in member-member and members-management relations. The experiences from the survey clearly show that moral hazard exists in the producer organization. According to my results, though its measure cannot be regarded numerically considerable, its negative effect on cooperative activity can be proved with statistical examinations. Its effect can be divided into two aspects: besides a direct effect, an indirect one can also be detected, which means that moral hazard is able to reduce producers’ willingness to cooperate by eroding trust. Moreover, our results have clearly pointed out that moral hazard has a negative impact on member-member and members-management relations to varying degrees and through different mechanisms. In addition to the above tests, the empirical testing of another model called Sholtes trust model has been carried out, too. The validating was successful, so the model - which attributes trust to the faith in the partner’s loyalty and capability - is basically acceptable. The argument says that high-level trust can be observed among partners only when faith both in loyalty and capability is strong enough. The research, however, revealed that the above-mentioned two factors determine it in a different way: regarding trust between members, the faith in capability is more important; while trust towards the management is more determined by faith in loyalty.
JEL code: Q12, Q13
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Liljeroos, Maria, Susanna Ågren, Tiny Jaarsma, and Anna Stromberg. "Dialogues between nurses, patients with heart failure and their partners during a dyadic psychoeducational intervention: a qualitative study." BMJ Open 7, no. 12 (December 2017): e018236. http://dx.doi.org/10.1136/bmjopen-2017-018236.
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ObjectivesTo describe nurses’ documentation of the content in a psychoeducational intervention inspired by Stuifbergen’s model addressing cognitive, supportive and behavioural needs of patient–partner dyads affected by heart failure.DesignA descriptive qualitative design was used analysing nurses’ documentation in a dialogue guide based on a health promotion model.SettingsThe dialogue guide was used during three nurse-led sessions at two heart failure clinics in Sweden with patients affected with heart failure and their partners during the years 2005–2008.ParticipantsThe dialogue guides from 71 patient–partner dyads were analysed using direct deductive content analyses. Patients’ mean age was 69 years and 31% were female, partners’ mean age was 67 years and 69% were female.ResultsThe findings supported the conceptual health promotion model and identified barriers, recourses and self-efficacy described by the dyads within each category.ConclusionThe dyads described that during the sessions, they had gained enhanced knowledge and greater confidence to handle their life situation and expressed that they needed psychoeducational support during the whole illness trajectory. The results may guide and help to improve content and quality when caring for patients affected with heart failure and their partners and also when designing new interventions.Trial registration numberNCT02398799; Post-results.
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Gino, Francesca, and Lamar Pierce. "Dishonesty in the Name of Equity." Psychological Science 20, no. 9 (September 2009): 1153–60. http://dx.doi.org/10.1111/j.1467-9280.2009.02421.x.
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Under what conditions do people act dishonestly to help or hurt others? We addressed this question by examining the influence of a previously overlooked factor—the beneficiary or victim of dishonest acts. In two experiments, we randomly paired participants and manipulated their wealth levels through an initial lottery. We then observed how inequity between partners influenced the likelihood of one dishonestly helping or hurting the other, while varying the financial incentives for dishonest behavior. The results show that financial self-interest cannot fully explain people's tendency to dishonestly help or hurt others. Rather, such dishonesty is influenced by emotional reactions to wealth-based inequity, even when the dishonesty bears a personal financial cost. Envy evoked by negative inequity led to hurting behavior, whereas guilt induced by positive inequity motivated helping behavior. Finally, inequity between the partner and third parties triggered dishonest helping through empathy with the partner.
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Barger, Sarah, Sean D. Sullivan, Gary H. Lyman, Dawn L. Hershman, Ari Bell-Brown, Kate Watabayashi, Kathryn Egan, et al. "The influence of patient engagement on the design and implementation of a clinical trial to improve cancer care delivery." Journal of Clinical Oncology 36, no. 30_suppl (October 20, 2018): 223. http://dx.doi.org/10.1200/jco.2018.36.30_suppl.223.
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223 Background: We have engaged 10 patient partners in the development and implementation of S1415CD, a five-year pragmatic clinical trial currently in year 3 assessing the effectiveness of a guideline-based colony stimulating factor standing order intervention (NCT02728596). Patient partners serve as part of a 21-person External Stakeholder Advisory Group (ESAG), which also includes providers, payers and guidelines experts. This abstract explores the influence of patient partners on the design, tools and implementation of S1415CD Methods: Patient partners advise the study team on protocol development, patient-facing materials and implementation challenges over four teleconferences each year, annual in-person meetings and targeted email communication. All patient partner input from 2014-2017 was tracked, collected and reviewed for impact on the trial. Results: Input from patient partners led to the refinement of the study’s patient-reported outcome (PRO) survey questions, the creation of a highly utilized patient brochure, and the formation of talking points for clinic staff to help explain the study. Patient partners in conjunction with high performing sites helped develop strategies for sites with lower patient accrual to optimize the approach and consent of study participants. Conclusions: The sustained engagement of patient partners in S1415CD ensured patient-centeredness in trial design and guided the development of PRO surveys and relevant, high quality patient-facing materials. Drawing on experiential knowledge and insights from their roles as caregivers and advocates, patient partners provided valuable feedback that influenced patient approach and engagement in the study. Embedding patient partners in the research continuum has catalyzed critical discussions and problem solving among the patient partners and study team, which has led to patient-centered solutions to study challenges. Clinical trial information: NCT02728596.
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Sullivan, Brittney J., and Janet Prvu Bettger. "Community-Informed Health Promotion to Improve Health Behaviors in Honduras." Journal of Transcultural Nursing 29, no. 1 (September 26, 2016): 14–20. http://dx.doi.org/10.1177/1043659616670214.
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Background: Honduras is the second poorest country in Central America. The already high burden of disease is disproportionately worse among individuals with less education and limited access to health care. Community engagement is needed to bridge the gap in health care resources with the need for health promotion and education. Culturally relevant health promotion activities can foster transcultural partnerships. Purpose: The purpose of this study was to partner nursing students with village leaders to assess a community’s health needs and implement health promotion activities in Honduras. Design: Participatory action research was used in the study. Method: U.S. nursing students ( n = 4) partnered with a nonprofit organization and community partners in Villa Soleada to interview mothers in Villa Soleada, a Honduran village of 44 families, and implement health promotion activities targeted to the health priorities of their families. Results: Structured interviews with 24 mothers identified gastrointestinal issues, health care access and quality, and malaria as the top three priorities. Ninety-two percent of respondents were interested in nurse-led health promotion. Activities engaged new community partners. Discussion: This partnership and learning model was well received and sustainable. The U.S. nurses involved in the partnership gained exposure to Honduran health issues and led locally tailored health promotions in Villa Soleada. The community’s response to health promotion were positive and future activities were planned. Implications: Nursing student’s immersion experiences to support population-based health activities in low-resource settings are a replicable model that can help build healthier communities with a sustainable local infrastructure. Transcultural nursing experiences enhance students’ perspectives, increase personal and professional development, strengthen nursing students’ critical thinking skills, and for some students, confirm their desire to practice in an international arena.
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Kolben, Kevin. "Trade, Development, and Migrant Garment Workers in Jordan." Middle East Law and Governance 5, no. 1-2 (2013): 195–226. http://dx.doi.org/10.1163/18763375-00501006.
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This article examines the consequences of the international community’s and, more specifically, the United States’ efforts to help Jordan develop through the use of Preferential Trade Arrangements (PTAs). Specifically, it looks at how an effort to encourage garment and apparel manufacturing in Jordan, through special tariff reductions that are not generally available to other trading partners of the U.S., led to some unintended and undesirable results from the perspective of labor rights compliance and development. The article concludes that PTAs that intend to promote development and labor rights need to examine the specific labor market and economic context of trading partner countries to determine how to best design trade policy.
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Drever, John L., Aysegul Yildirim, and Mattia Cobianchi. "London Street Noises: A Ground-Breaking Field Recording Campaign from 1928." Acoustics 3, no. 1 (February 18, 2021): 118–36. http://dx.doi.org/10.3390/acoustics3010010.
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In a leading article by Sir Percival Philips in the UK popular newspaper, the Daily Mail, July 16, 1928, came the following headlines: “Millions Lost by Noise – Cities’ Worst Plague – Menace to Nerves and Health – What is Being Done to Stop it”. The article was supported by research from Prof Henry J. Spooner, who had been researching and campaigning on the ill-effects of noise and its economic impact. The article sparked subsequent discussion and follow-up articles in the Daily Mail and its international partners. In an era of rapid technological change, that was on the cusp of implementing sound pressure measurements, the Daily Mail, in collaboration with the Columbia Graphophone Company Ltd, experimented with sound recording technology and commentary in the field to help communicate perceived loudness and identify the sources of “unnecessary noise”. This resulted in the making of series of environmental sound recordings from five locations across central London during September 1928, the findings of which were documented and discussed in the Daily Mail at the time, and two recordings commercially released by Columbia on shellac gramophone disc. This was probably the first concerted anti-noise campaign of this type and scale, requiring huge technological efforts. The regulatory bodies and politicians of the time reviewed and improved the policies around urban noise shortly after the presentation of the recordings, which were also broadcast from the BBC both nationally and internationally, and many members of the public congratulated and thanked the Daily Mail for such an initiative. Despite its unpreceded scale and impact, and the recent scholarly attention on the history of anti-noise campaigning, this paper charts and contextualises the Daily Mail’s London Street Noise campaign for the first time. As well as historical research, this data has also been used to start a longitudinal comparative study still underway, returning to make field recordings on the site on the 80th and 90th anniversaries and during the COVID-19 lockdown, and shared on the website londonstreetnoises.co.uk.
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Compagnon, Daniel. "« Mugabe and partners (Pvt) Ltd » ou l'investissement politique du champ économique." Politique africaine 81, no. 1 (2001): 101. http://dx.doi.org/10.3917/polaf.081.0101.
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Congello, Neomie C., and Deborah Koniak-Griffin. "Review: Partner Support and Physical Activity among Mexican American Women." Ethnicity & Disease 28, no. 4 (October 17, 2018): 555–60. http://dx.doi.org/10.18865/ed.28.4.555.
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Objective: Global recommendations on physical activity for noncommunicable disease prevention can be promoted using partner support strategies among women of Mexican descent and other ethnicities.Design/Methods: This systematic review utilized a multifaceted ecological approach by focusing comprehensively on community, individual, and social factors influencing physical activity. PubMed, SAGE Publications, EBSCO, ResearchGate, the Cochrane Library and Google Scholar search engines were used to find research on physical activity, with inclusion criteria of Mexican American women, aged ≥ 18 years, comprising at least 50% of study population sizes.Main Outcome Measures: An initial search of 232 articles with subsequent searches from reference lists led to selection of a mixture of qualitative (3), mixed methods (3), and intervention (1) studies reporting partner support for physical activity as perceived by women.Results: Primarily, studies have conceptualized physical activity as leisure time activities. Few studies have considered multiple ecological factors in examining influences of physical activity among women. Importantly, how women perceive support for physical activity received from partners has been shown to influence their levels of activity.Conclusions: Conceptualization of physical activity restricted only to leisure time eliminates other domains that a broader definition of the term encompasses. Future studies are needed to investigate partner support influences on the overall physical activity of Mexican American women within a larger ecological context. Careful attention to partner support for physical activity engagement can help ameliorate and prevent chronic diseases both nationally and around the world. Ethn Dis. 2018;28(4):555-560;doi:10.18865/ed.28.4.555.
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McKendrick, Ewan. "Pirelli re-examined." Legal Studies 11, no. 3 (November 1991): 326–37. http://dx.doi.org/10.1111/j.1748-121x.1991.tb00046.x.
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One of the interesting facets of the decision of the House of Lords in Murphy v Brentwood District Council is the fresh interpretation which it has placed upon some of the earlier leading authorities. One case which has been subjected to this process of re-interpretation is the decision of the House of Lords in Pirelli General Cable Works Ltd v Oscar Faber & Partners. It was rationalised by Lord Keith as a case which fell ‘within the principle of Hedley Byrne & Co Ltd v Heller & Partners Ltd’. The aim of this short note is to subject this re-interpretation to examination and to suggest that, ironically, its consequence may be the adoption of the very proposition of law rejected by their Lordships in Pirelli, namely that the cause of action accrued on the date on which the damage was discovered or should, with the exercise of reasonable diligence, have been discovered.
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Boker, Steven M., Jeffrey F. Cohn, Barry-John Theobald, Iain Matthews, Timothy R. Brick, and Jeffrey R. Spies. "Effects of damping head movement and facial expression in dyadic conversation using real–time facial expression tracking and synthesized avatars." Philosophical Transactions of the Royal Society B: Biological Sciences 364, no. 1535 (December 12, 2009): 3485–95. http://dx.doi.org/10.1098/rstb.2009.0152.
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When people speak with one another, they tend to adapt their head movements and facial expressions in response to each others' head movements and facial expressions. We present an experiment in which confederates' head movements and facial expressions were motion tracked during videoconference conversations, an avatar face was reconstructed in real time, and naive participants spoke with the avatar face. No naive participant guessed that the computer generated face was not video. Confederates' facial expressions, vocal inflections and head movements were attenuated at 1 min intervals in a fully crossed experimental design. Attenuated head movements led to increased head nods and lateral head turns, and attenuated facial expressions led to increased head nodding in both naive participants and confederates. Together, these results are consistent with a hypothesis that the dynamics of head movements in dyadicconversation include a shared equilibrium. Although both conversational partners were blind to the manipulation, when apparent head movement of one conversant was attenuated, both partners responded by increasing the velocity of their head movements.
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Sewerin, P., R. Freynhagen, T. Tölle, M. Hammer, C. Baerwald, J. Walter, R. Schröder, M. Schneider, and R. Baron. "THU0478 IS NEUROPATHIC PAIN IN INFLAMMATORY RHEUMATIC DISORDERS AN UNDERESTIMATED PROBLEM? RESULTS FROM THE GERMAN PAINDETECT DATABASE." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 476–77. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4457.
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Background:The aim of the study was to investigate the impact and relevance of neuropathic pain in inflammatory rheumatic disorders (IRD) and osteoarthritis (OA).Objectives:Pain is one of the main symptoms in patients with IRD and OA. To enhance a mechanistic based treatment of pain the differentiation between nociceptive and neuropathic pain via screening tools (e.g. painDETECT questionaire) might possibly be helpful. The goal of the study was to investigate (1) if neuropathic pain is a significant burden for patients with IRD and (2) if pain patterns differs from degenerative joint diseases such as OA in over 9.000 patients in each group.Methods:painDETECT is a questionnaire that has been evaluated and used in numerous clinical trials to detect neuropathic pain in various diseases. The collected data is centrally managed and evaluated. In total (end of 2019) 395.984 patients have been documented. Out of the painDETECT database 9256 patients with IRD and 9436 patients with OA were extracted, analyzed and compared on their neuropathic pain pattern (screening was performed using the painDETECT-questionaire., PDQ). Secondary parameters were: intensity of pain, functional status, depression, chronicity and sleep disorder. Patients had been recruited from general practitioners (GPs), Rheumatologists, Orthopedics and Neurologists from 862 office-based physicians into the painDETECT-database. This project is an open label registry study in Germany.Results:The median PDQ-score of patients with inflammatory rheumatic disorders adds up to 14,2 (1-38) and of OA patients to 13,8. 28.7% of inflammatory rheumatic disorders and 27.2% of OA-patients showed signs for neuropathic pain by positive PDQ. The difference was according to this high patient numbers statistically significant (P=0.0015). VAS-Score, Depressions-Score, Chronicity -Score and Functional -Score showed no clinically relevant differences between these two groups.Conclusion:Nearly one third of patients with IRD as well as patients with OA showed neuropathic pain components by using PDQ. Despite increasingly better disease control through more effective therapies, pain still remains a major burden for many patients and has a profound impact on their quality of life. The present data indicate a surprisingly high symptoms of neuropathic pain even in IRD patients and should be considered in the management of our patients. A new documentation system for Rheumatologists (RheumaAssist) could help to address these questions.Percentage of PDQ-categories (negative/unclear/positive) for patients with inflammatory rheumatic disorders (IRD) or Arthrosis (OA)Acknowledgments:This investigation was supported within a grant of Pfizer Deutschland GmbH.Disclosure of Interests: :Philipp Sewerin Grant/research support from: AbbVie Deutschland GmbH & Co. KGBristol-Myers Squibb Celgene GmbHLilly Deutschland GmbHNovartis Pharma GmbH Pfizer Deutschland GmbHRheumazentrum Rhein-Ruhr, Consultant of: AMGEN GmbH AbbVie Deutschland GmbH & Co. KG Biogen GmbHBristol-Myers Squibb Celgene GmbH Chugai Pharma arketing Ltd. / Chugai Europe GmbHHexal Pharma Janssen-CilagGmbH Johnson & Johnson Deutschland GmbHLilly Deutschland GmbH / Lilly Europe / Lilly Global Novartis Pharma GmbH Pfizer Deutschland GmbH Roche Pharma Rheumazentrum Rhein-Ruhr Sanofi-Genzyme Deutschland GmbH Swedish Orphan Biovitrum GmbH UCB Pharma GmbH, Speakers bureau: AMGEN GmbH AbbVie Deutschland GmbH & Co. KG Biogen GmbHBristol-Myers Squibb Celgene GmbH Chugai Pharma arketing Ltd. / Chugai Europe GmbHHexal Pharma Janssen-CilagGmbH Johnson & Johnson Deutschland GmbHLilly Deutschland GmbH / Lilly Europe / Lilly Global Novartis Pharma GmbH Pfizer Deutschland GmbH Roche Pharma Rheumazentrum Rhein-Ruhr Sanofi-Genzyme Deutschland GmbH Swedish Orphan Biovitrum GmbH UCB Pharma GmbH, Rainer Freynhagen Consultant of: AOP Orphan Pharma, Grünenthal, Lilly, Merck, Mitsubishi Tanabe Pharma, Pfizer, Scilex Pharmaceutics, Speakers bureau: AOP Orphan Pharma, Grünenthal, Lilly, Merck, Mitsubishi Tanabe Pharma, Pfizer, Scilex Pharmaceutics, Thomas Tölle Consultant of: AOP Orphan, Almiral Hermal, Bionest Partners, Benkitt Renkiser, Grünenthal, Hexal, Indivior, Kaia Health, Lilly, Medscape Mundipharma, MSD, Novartis, Pfizer, Recordati Pharma, Sanofi-Aventis, and TAD Pharma, Speakers bureau: AOP Orphan, Almiral Hermal, Bionest Partners, Benkitt Renkiser, Grünenthal, Hexal, Indivior, Kaia Health, Lilly, Medscape Mundipharma, MSD, Novartis, Pfizer, Recordati Pharma, Sanofi-Aventis, and TAD Pharma, Michael Hammer Consultant of: Abbvie, Pfizer, Medac and Janssen, Speakers bureau: Abbvie, Pfizer, Medac and Janssen, Christoph Baerwald Consultant of: CGB received speaker or consulting fees from AbbVie, Paid instructor for: CGB received speaker or consulting fees from AbbVie, Speakers bureau: CGB received speaker or consulting fees from AbbVie, Jochen Walter Consultant of: Pfizer, Speakers bureau: AbbVie, Frauenhofer Institut, Gilead, Janssen-Cilag, Medac, Novartis, Pfizer, Ralf Schröder Shareholder of: Pfizer Pharma GmbH, Employee of: Pfizer Pharma GmbH, Matthias Schneider Grant/research support from: GSK, UCB, Abbvie, Consultant of: Abbvie, Alexion, Astra Zeneca, BMS, Boehringer Ingelheim, Gilead, Lilly, Sanofi, UCB, Speakers bureau: Abbvie, Astra Zeneca, BMS, Chugai, GSK, Lilly, Pfizer, Sanofi, Ralf Baron Consultant of: RB received speaker or consulting fees from AbbVie, Paid instructor for: RB received speaker or consulting fees from AbbVie, Speakers bureau: RB received speaker or consulting fees from AbbVie
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Hawkins, Michelle D., Vankita Brown, and Jannie Ferrell. "Assessment of NOAA National Weather Service Methods to Warn for Extreme Heat Events." Weather, Climate, and Society 9, no. 1 (December 9, 2016): 5–13. http://dx.doi.org/10.1175/wcas-d-15-0037.1.
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Abstract Recent climate studies have predicted a future with longer, more intense, and more frequent heat events. Evolving challenges presented by this paradigm necessitate an assessment of current efforts to warn for extreme heat events. NOAA’s National Weather Service (NWS) Weather Forecast Offices (WFOs) issue Excessive Heat Watch, Excessive Heat Warning, and Heat Advisory products as conditions warrant. In the fall of 2013 the NWS conducted an internal assessment with its WFOs to 1) document variations in the usage of heat-based watch, warning, and advisory hazard messages (products) across the country; 2) learn about the degree to which locally developed criteria are applied to forecaster decision-making processes in issuing these products; and 3) gather ideas for enhancing communication of expected excessive heat events in general. Survey responses indicate that WFOs selectively use one or a combination of products, and that various methodologies are used to develop criteria for issuing heat products. Given that forecasters use meteorological and nonmeteorological factors when deciding to issue heat products, forecaster judgment is a crucial element of the warning process. Results also revealed partner confusion due to inconsistent heat product issuance criteria. Suggestions were made for eliminating or revising existing products and policies, or creating new products, policies, or issuance criteria. Results of the survey led the NWS to investigate approaches for achieving higher levels of consistency in heat product issuance criteria, and to engage health partners to examine how heat product issuance criteria could incorporate the known health impacts of heat exposure.
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Marín, Sabrina, Mayra Cortés, Mauricio Acosta, Karla Delgado, Camila Escuti, Diego Ayma, and Cecilia Demergasso. "From Laboratory towards Industrial Operation: Biomarkers for Acidophilic Metabolic Activity in Bioleaching Systems." Genes 12, no. 4 (March 25, 2021): 474. http://dx.doi.org/10.3390/genes12040474.
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In the actual mining scenario, copper bioleaching, mainly raw mined material known as run-of-mine (ROM) copper bioleaching, is the best alternative for the treatment of marginal resources that are not currently considered part of the profitable reserves because of the cost associated with leading technologies in copper extraction. It is foreseen that bioleaching will play a complementary role in either concentration—as it does in Minera Escondida Ltd. (MEL)—or chloride main leaching plants. In that way, it will be possible to maximize mines with installed solvent-extraction and electrowinning capacities that have not been operative since the depletion of their oxide ores. One of the main obstacles for widening bioleaching technology applications is the lack of knowledge about the key events and the attributes of the technology’s critical events at the industrial level and mainly in ROM copper bioleaching industrial operations. It is relevant to assess the bed environment where the bacteria–mineral interaction occurs to learn about the limiting factors determining the leaching rate. Thus, due to inability to accurately determine in-situ key variables, their indirect assessment was evaluated by quantifying microbial metabolic-associated responses. Several candidate marker genes were selected to represent the predominant components of the microbial community inhabiting the industrial heap and the metabolisms involved in microbial responses to changes in the heap environment that affect the process performance. The microbial community’s predominant components were Acidithiobacillus ferrooxidans, At. thiooxidans, Leptospirillum ferriphilum, and Sulfobacillus sp. Oxygen reduction, CO2 and N2 fixation/uptake, iron and sulfur oxidation, and response to osmotic stress were the metabolisms selected regarding research results previously reported in the system. After that, qPCR primers for each candidate gene were designed and validated. The expression profile of the selected genes vs. environmental key variables in pure cultures, column-leaching tests, and the industrial bioleaching heap was defined. We presented the results obtained from the industrial validation of the marker genes selected for assessing CO2 and N2 availability, osmotic stress response, as well as ferrous iron and sulfur oxidation activity in the bioleaching heap process of MEL. We demonstrated that molecular markers are useful for assessing limiting factors like nutrients and air supply, and the impact of the quality of recycled solutions. We also learned about the attributes of variables like CO2, ammonium, and sulfate levels that affect the industrial ROM-scale operation.
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'Sullivan, Gael. "The Saathiya Trusted Partner Program in India: Meeting Young Couples' Reproductive Health Needs." Social Marketing Quarterly 14, no. 3 (August 26, 2008): 109–20. http://dx.doi.org/10.1080/15245000802261324.
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Saathiya, or “trusted partner” in Hindi, is an apt name for a new private sector social marketing initiative designed to help young married couples in Lucknow, Uttar Pradesh make informed choices about how many children to have and when to start their families. Supported by funding from the U.S. Agency for International Development (USAID), contributions from eight different pharmaceutical and medical association partners, and technical guidance from Abt Associates through the Private Sector Partnerships-One Project (PSP-One), Saathiya was launched in October 2007 at a press conference led by local government and civic officials, USAID, and the medical community. Program innovations include an intervention/control research design to track changes in family planning-related knowledge, attitudes, and behavior, expansion of the service delivery network to include traditional medical doctors, a “basket” of four different short-acting contraceptives that are cobranded with the Saathiya program, and a youth-friendly promotional strategy that employs a helpline, short message service (SMS) text messaging, and the Internet in additional to traditional channels.
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Wyse, Marion. "Developing a method for cross-cultural dialogue with Chinese." Language and Dialogue 4, no. 3 (November 24, 2014): 404–24. http://dx.doi.org/10.1075/ld.4.3.03wys.
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China is inviting foreigners into what was a closed society. Few are prepared for what they meet. This article hopes to help with an updated method of dialogue produced by Xiamen University’s doctoral class in Cultural Linguistics, using the “Dialogue Decalogue” of Dr. Leonard Swidler and the Harvard Negotiation Project as models developed in Mediterranean-based cultures. After re-defining ‘negotiate’ and ‘dialogue’, the group examined the five preconditions and found little that matched Chinese assumptions. They then restated Swidler’s ten steps to include Chinese assumptions using linguistics and historical precedent. The language barrier is formidable, and the habit of closing out ‘outsiders’ runs deep. The hermeneutic of suspicion must be applied to anything learned due to the tendency of a Chinese to say what s/he thinks the conversation partner wants to hear. This is viewed as non-productive by Mediterranean-based cultures.
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Grover, Gitte, and Willi Fast. "Alberta making strides in mixedwood management." Forestry Chronicle 83, no. 5 (September 1, 2007): 714–18. http://dx.doi.org/10.5558/tfc83714-5.
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Driven by issues of economics, productivity, biodiversity and climate change, mixedwood management is becoming increasingly attractive. For silviculture to embrace and capitalize on natural stand dynamics, complex processes and interactions must be understood. To facilitate focused, applied research, ten Alberta forest companies have joined forces to cooperatively advance the science and management of boreal aspen/white spruce mixedwood forests. Members of the Mixedwood Management Association have committed collective research funds to develop and test practices that will sustain fibre supply, biodiversity, social and ecological values in Alberta's mixedwood forests. Forest industry members include Ainsworth Engineered Canada LP., Alberta-Pacific Forest Industries Inc., Canadian Forest Products Ltd., Daishowa-Marubeni International Ltd., Footner Forest Products Ltd., Millar Western Forest Products Ltd., Tolko Industries Ltd., Slave Lake Pulp/Alberta Plywood Ltd., Vanderwell Contractors (1971) Ltd. and Weyerhaeuser Company Ltd. The Alberta government and the University of Alberta are supporting partners in the Association. The Association's goals are to increase knowledge of aspen/white spruce mixed forests in the areas of growth and yield, crop planning, monitoring, understory protection and decision support tools. This paper highlights some of the Association-sponsored research projects. Key words: Alberta, Mixedwood Management Association, research, growth and yield, crop plans
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Krahmer, Ana. "Digital newspaper preservation through collaboration." Digital Library Perspectives 32, no. 2 (May 9, 2016): 73–87. http://dx.doi.org/10.1108/dlp-09-2015-0015.
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Purpose The Texas Digital Newspaper Program (TDNP) supports newspaper preservation and access for any title in Texas, from any date, any location and representing any community. As an active member of the Texas Press Association, TDNP also supports large-scale preservation of born-digital newspaper PDF issues for member publishers. This paper aims to explore how the early days of TDNP built a strong foundation of collaboration and support for large-scale preservation projects, including support for preserving a state press association PDF newspaper collection. Design/methodology/approach This paper is a case study of a collaborative endeavor to create a large-scale, statewide digital newspaper preservation hub in Texas. This paper details how individual partnerships led to new and larger partnerships. Figures and tables represent numbers of partner institutions served, numbers of newspapers preserved and screenshots of how these items appear within collections on the digital repository environment of The Portal to Texas History. This paper concludes with recommendations for groups interested in developing their own collaborative projects. Findings As a case study, the data explored include numbers of partnering institutions, materials contributed by partnering institutions and how these numbers help to forward the TDNP agenda. Practical Implications The final recommendations are lessons learned through collaboration, and the implications are real-world advice from the partners developed through the TDNP. Originality/value Hosting over 3.25 million pages of newspapers, the TDNP has become an enormous hub of newspaper preservation in Texas, and it is unique in the numbers of partners it supports and the numbers of pages it is able to host for free access via The Portal to Texas History. This paper is intended to help other groups across the world build their own collaborative preservation efforts, and it offers pragmatic advice derived from hands-on experience.
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Fialkow, Michael F., Carrie M. Snead, and Jay Schulkin. "New Partner Recruitment to Rural Versus Urban Ob-Gyn Practices." Health Services Research and Managerial Epidemiology 4 (January 1, 2017): 233339281772398. http://dx.doi.org/10.1177/2333392817723981.
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Purpose: The purpose of this pilot study was to investigate the recruitment efforts of practicing obstetrics and gynecology (ob-gyns) from rural and urban practices. Method: The authors surveyed practicing ob-gyns from 5 states in the Pacific Northwest in 2016 about their background, practice setting, practice profile, partner recruitment, and retention. Results: Seventy-three patients completed the study (53.2% response rate). Thirty-seven percent of respondents work in an urban practice and 43% have a rural practice, with the remainder in a suburban setting. A majority of the respondents attempted to recruit a new partner in the past 5 years. Respondents were most interested in experience and diversity in new recruits. Urban respondents, however, were more interested in hiring those with specialized skills (χ2 = 7.842, P = .02) than rural providers who were more interested in partners familiar with their community (χ2= 7.153, P = .03). Reasons most often cited to leave their practice were reimbursement, limited social/marital options, and workload, other than rural providers who more often also cited lack of access to specialty care (χ2= 13.256, P = .001). Rural providers were more likely to cite marital and family status as an advantage to recruitment, whereas urban and suburban providers were more often neutral. Conclusions: Reduced access to care has led to significant health disparities for women living in rural communities. Understanding which providers are most likely to be successful in these settings might help preserve access as our health-care systems evolves.
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Haibing, Liu, and Kan Yuyue. "Business model innovation of Qingdao Youzhu Decoration Company." E3S Web of Conferences 214 (2020): 02046. http://dx.doi.org/10.1051/e3sconf/202021402046.
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There are many problems in home decoration industry, such as imperfect industry system, lack of integrity of enterprises, low quality of construction personnel, etc. However, Qingdao Youzhu Home Decoration Co., Ltd. has achieved rapid growth with the innovation of business model. Therefore, based on Qingdao Youzhu Home Decoration Co., Ltd., this paper attempts to analyze the company’s business model innovation. The conclusion shows that the company’s business model canvas includes nine modules of important partners, value proposition, key business, core resources, customer segmentation, customer relationships, Channel access, revenue sources and cost structure, and each module plays an important role.
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Clark, J., C. Parry, M. Rowlands, A. Tessier, and D. Mazzuchelli. "The Glenlivet Field, Block 214/30a, UK Atlantic Margin." Geological Society, London, Memoirs 52, no. 1 (2020): 958–66. http://dx.doi.org/10.1144/m52-2018-24.
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AbstractThe Glenlivet Field, located in Block 214/30a within the Faroe–Shetland Basin, was put on production in August 2017. It lies approximately 70 km NW of the Shetland Islands, in a water depth of c. 440 m. The development consists of two subsea wells that produce gas condensate from the Paleocene Vaila Formation, which comprises deep-water turbidite deposits with excellent petrophysical properties. It is part of a joint development scheme along with the Edradour Field that sees the commingled multiphase production transported to the Shetland Gas Plant via tie-back to the pre-existing Laggan–Tormore flowlines. Glenlivet is operated by Total E&P UK Ltd under the P1195 licence since September 2014 with Ineos E&P (UK) Ltd and SSE E&P UK Ltd as partners.
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Ballan, Michelle S., Molly Burke Freyer, Lauren Powledge, and C. Nathan Marti. "Intimate Partner Violence Among Help-Seeking Deaf Women: An Empirical Study." Violence Against Women 23, no. 13 (August 30, 2016): 1585–600. http://dx.doi.org/10.1177/1077801216664428.
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Deaf women face heightened rates of intimate partner violence (IPV) compared with hearing women, yet limited research has focused on IPV among this population. Empirical studies are warranted to examine the unique experiences and resource needs of Deaf women, along with barriers excluding Deaf participants from IPV research and service provision. Our study addresses these gaps by providing a profile of 80 Deaf women attending an IPV program serving individuals with disabilities. Demographic and psychosocial characteristics, referral channels that led women to the program, and services sought post-referral are discussed to help guide best practices with Deaf survivors of IPV.
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Lendvai, Edina. "Logistic Questions and Solutions at a Special Slaughter Company, Beck-Hús LTD." Analecta Technica Szegedinensia 11, no. 2 (August 1, 2017): 16–21. http://dx.doi.org/10.14232/analecta.2017.2.16-21.
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In our work, we analysed the most logistic problem of the meat production and distribution. To reach our aims, we made an interview with the manager of a meat small enterprise. There are 2 main activities, the cutting is in Csávoly (little village, near the Baja), and the producing is in Baja. We asked the manager about these main activities, their capacity, the most important products. We have got a lot of information about their partners, the terms of payments, and the main problems. We tried to make a proposal and give some advice to develop the factory.
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Bennett, Sally, Catherine Travers, Jacki Liddle, Sandra Smith, Lindy Clemson, Maria O’Reilly, Michelle Allen, et al. "Acceptability and willingness to participate in the Tailored Activity Program: perceptions of people living with dementia, their care partners and health professionals." Brain Impairment 21, no. 3 (October 28, 2020): 259–73. http://dx.doi.org/10.1017/brimp.2020.15.
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AbstractObjectives:The Tailored Activity Program (TAP) is an evidence-based occupational therapist-led intervention for people living with dementia and their care partners at home, developed in the USA. This study sought to understand its acceptability to people living with dementia, their care partners, and health professionals, and factors that might influence willingness to participate prior to its implementation in Australia.Methods:This study used qualitative descriptive methods. Semi-structured interviews were conducted with people living with dementia in the community (n = 4), their care partners (n = 13), and health professionals (n = 12). People living with dementia were asked about health professionals coming to their home to help them engage in activities they enjoy, whereas care partners’ and health professionals’ perspectives of TAP were sought, after it was described to them. Interviews were conducted face-to-face or via telephone. All interviews were recorded and transcribed. Framework analysis was used to identify key themes.Results:Analysis identified four key themes labelled: (i) TAP sounds like a good idea; (ii) the importance of enjoyable activities; (iii) benefits for care partners; and (iv) weighing things up. Findings suggest the broad, conditional acceptability of TAP from care partners and health professionals, who also recognised challenges to its use. People living with dementia expressed willingness to receive help to continue engaging in enjoyable activities, if offered.Discussion:While TAP appeared generally acceptable, a number of barriers were identified that must be considered prior to, and during its implementation. This study may inform implementation of non-pharmacological interventions more broadly.
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Clark, J., D. Mazzuchelli, M. Rowlands, N. Jebara, and C. Parry. "The Edradour Field, Block 206/4a, UK Atlantic Margin." Geological Society, London, Memoirs 52, no. 1 (2020): 952–57. http://dx.doi.org/10.1144/m52-2018-23.
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AbstractThe Edradour Field, located in Licence P1453 on Block 206/4a of the Faroe–Shetland Basin, was put on production in August 2017. It lies c. 50 km NW of the Shetland Islands in a water depth of c. 300 m, and consists of one subsea well that produces gas condensate from the Albian Black Sail Member of the Commodore Formation. It is part of a joint development scheme along with the Glenlivet Field that sees the commingled multiphase production transported to the Shetland Gas Plant via tieback to the pre-existing Laggan–Tormore flowlines. The Edradour single well development has reserves of 21 MMboe from a gas initially-in-place of 142 bcf. It is operated by Total E&P UK Ltd under the P1453 licence with Ineos E&P (UK) Ltd and SSE E&P UK Ltd as partners.
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Herbaux, Charles, Christoph Kornauth, Stéphanie Poulain, Olivier Tournilhac, Mary C. Collins, Rebecca Valentin, Stephen Jun Fei Chong, et al. "Characterizing the Anti-Apoptotic Dependencies of T-Cell Prolymphocytic Leukemia Identifies HDAC and JAK/STAT Pathway Inhibitors As Promising Combination Partners to Augment Bcl-2 Targeted Killing By Venetoclax." Blood 134, Supplement_1 (November 13, 2019): 807. http://dx.doi.org/10.1182/blood-2019-126773.
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Introduction: Response to conventional therapies for patients with T-cell prolymphocytic leukemia (T-PLL) is usually poor and is associated with short survival. The BCL-2 antagonist venetoclax was recently found to have some clinical activity in this disease (B Boidol et al., Blood, 2017); however, these early data suggest that this drug will not provide prolonged response when given as monotherapy. Several other drug classes have demonstrated preclinical activity in T-PLL, including HDAC inhibitors (HDACi), JAK/STAT inhibitors (JAK/STATi), and TCR pathway inhibitors (TCRi), particularly ITK inhibitors. To determine which drug(s) may be the optimal combination partner(s) for venetoclax in T-PLL, we utilized a functional approach known as BH3 profiling. This assay measures how close a cell is to the threshold of apoptosis ("priming") and identifies which anti-apoptotic proteins a cell depends on for survival. We also utilized a variant known as dynamic BH3 profiling (DBP) to measure early changes in pro-apoptotic signaling after various drug treatments. Methods: Clinically annotated primary T-PLL patient samples were obtained from the French Innovative Leukemia Organization network after informed consent. Peripheral blood mononuclear cells were isolated by Ficoll and viably frozen and later thawed for the experiments. Baseline BH3 profiling to measure cytochrome C (cyto-C) release was performed as per Ryan et al., Methods, 2013, and DBP as per Montero et al., Cell, 2015. Viability was assessed by AnnexinV/Hoechst staining. Ex vivo drug treatments included: BH3 mimetics (BCL-2i: venetoclax (VEN), MCL-1i: AZD5991, S63845), HDACi (belinostat = BEL), JAK/STATi (ruxolitinib = RUX) and TCRi (PRN694 = PRN). Protein expression was assessed by standard Western Blot. Primary CLL cells were used in some experiments as a comparator. To mimic the lymph node microenvironment, DBP and viability assays were performed in co-culture with the stromal cell line NK.tert. Tumoral DNA was also extracted, and we performed NGS on a panel of 29 genes, including ATM and TP53, as well as Sanger sequencing to assess for IL2R, JAK1, JAK3, STAT5B mutations. Statistical analyses were by unpaired and paired t-test with a two-tailed nominal p ≤ 0.05 considered as significant. Results: Samples were evaluated from 31 T-PLL patients. Baseline BH3 profiling revealed that, compared to CLL cells, T-PLL cells are less primed for apoptosis but have comparable dependency on MCL-1. BCL-2 dependency was found to be significantly lower in T-PLL than CLL (cyto-C release 48.8%; 62.7% p=0.0005), and to decrease further in the presence of stroma (Figure A, cyto-C release from 72.6% to 36.2%, p = 0.01). Consistent with our BH3 profiling results, the degree of BCL-2 dependency in T-PLL cells was strongly associated with the amount of apoptotic cell death induced by VEN (R2 -0.58, p=0.004), whereas MCL1 dependency was strongly associated with the cell death induced by the MCL1 inhibitors S63845 and AZD5991 (R2 -0.59, p=0.002 and R2 -0.68, p=0.0005 respectively, Figure B). We next performed DBP to assess the changes in apoptotic priming in T-PLL cells induced by HDACi, JAK/STATi and TCRi. To utilize doses similar to what can be achieved in patients, we assessed BEL 1mM, RUX 1mM and PRN 1mM. BEL and RUX increased overall T-PLL cell priming and BCL2 dependency (delta cyto-C release of 26.8%, p=0.004 and 14.8%, p=0.01 respectively Figure C), with no effect on MCL1 dependency. PRN had no significant effect on priming. Consistent with the DBP data, our viability assays showed that BEL and RUX induced significantly more cell death when combined with VEN compared to PRN (Figure D). Mutations in ATM, TP53, and JAK/STAT pathway genes were observed in cells from 35%, 6%, and 53% of patients, respectively, and did not impact the ex vivo activity of these drugs. Conclusion: We report the first data for BH3 profiling in T-PLL. We found that this disease is heterogeneously dependent on both BCL-2 and MCL-1, and that the lymph node microenvironment may decrease BCL-2 dependency. HDACi and JAK/STATi both enhance BCL-2 dependence, thereby sensitizing T-PLL cells to VEN. Ongoing studies will help further define the mechanism underlying these promising new combinations for T-PLL. Disclosures Herbaux: BMS: Honoraria; Gilead: Honoraria; Takeda: Honoraria; Abbvie: Honoraria; Janssen: Honoraria. Valentin:Roche: Other: Travel reimbursement; Abbvie Inc: Other: Travel reimbursement. Morschhauser:F. Hoffmann-La Roche Ltd: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Janssen: Honoraria; Bayer: Membership on an entity's Board of Directors or advisory committees; Epizyme: Membership on an entity's Board of Directors or advisory committees; Gilead: Membership on an entity's Board of Directors or advisory committees; BMS: Membership on an entity's Board of Directors or advisory committees; Celgene: Honoraria, Membership on an entity's Board of Directors or advisory committees. Staber:Roche: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Janssen: Honoraria, Speakers Bureau; Gilead: Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Celgene: Honoraria, Membership on an entity's Board of Directors or advisory committees; AbbVie: Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Takeda-Millenium: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; MSD: Honoraria, Speakers Bureau. Davids:AbbVie, Astra-Zeneca, Genentech, Janssen, MEI, Pharmacyclics, Syros Pharmaceuticals, Verastem: Consultancy; Acerta Pharma, Ascentage Pharma, Genentech, MEI pharma, Pharmacyclics, Surface Oncology, TG Therapeutics, Verastem: Research Funding; AbbVie, Acerta Pharma, Adaptive, Biotechnologies, Astra-Zeneca, Genentech, Gilead Sciences, Janssen, Pharmacyclics, TG therapeutics: Membership on an entity's Board of Directors or advisory committees; Research to Practice: Honoraria.
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Omelyanenko, V. I. "Complex integrated method of improvement of sports ballroom dance performance." Physical education of students 18, no. 6 (December 28, 2014): 49–53. http://dx.doi.org/10.15561/20755279.2014.0610.
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Purpose: to elaborate complex integrated method of psychological influence upon sport ballroom dancers for their quick response to assumed mistakes by executing other steps in training mode in place of given compositions. Material: 20 senior sport ballroom dancers: 10 - experimental group, 10 - control group. At the I stage dancers for participation in the experimental group with regard to their hypnosis ability for facilitation teaching dynamic meditation were selected. Sportsmen with the 2 nd -3 rd stage of hypnosis were enrolled to the experimental group. At the II stage the experimental group was trained in the method of dynamic meditation. For this, the static meditation was performed first, after this the test persons opened their eyes and without leaving the achieved result with help of the static state of meditation, practiced in dynamic meditation. At the III stage training in sports ballroom dances with introduction new steps changing the composition program sequence to composition was held. The coach evaluated response of the test persons in the state of the dynamic meditation. Results: at the II stage of the research on training in dynamic meditation the dancers of the experimental group needed 3-7 repetitions. At the III stage of the research 8 test persons had trained to response adequately to changes in the compositions within 10-15 repetitions. In the control group if a partner changed steps during performance of the composition it led to stop of the dancing couple. For 8 test persons in the experimental group steps replacement didn’t affect adversely the quality of the dance. The senior group of dancers studied new steps with great difficulty, their motion stereotype was formed badly, they preferred to dance compositions trained earlier. The seniors having insufficient technical background (2 persons) showed low abilities, they had bad memory, they spent 3 months for mastering new compositions. Conclusions: The methods elaborated by us providing for inclusion in the training process stand-alone dance steps in place of compensation steps, provided development of the dancers’ ability to respond quickly to assumed mistakes during dance performance. Mastering dynamic meditation depended on typological features of the nervous system: the higher hypnosis ability degree the better mastering. Women-partners of the experimental group who had high hypnosis ability degree and mastered dynamic meditation could quickly adequately response to the rapid changes in the composition performed by dance partner during dance. Consideration of possible errors trains a woman-partner’s ability to switch timely from one step to another. Using this method, improvement of professional skills of dancers accelerates greatly.
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Nystrom, Robert J., Adriana Prata, and Sarah Knipper Ramowski. "Measuring Positive Youth Development: The Development of a State Benchmark." Journal of Youth Development 3, no. 1 (June 1, 2008): 26–42. http://dx.doi.org/10.5195/jyd.2008.318.
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Public health benchmarks are indicators for well-being and health status that help inform program planning and policy development. In Oregon, recent efforts by a group of state agencies and community partners led to the adoption of a Positive Youth Development (PYD) benchmark by the Oregon Progress Board in 2006. In this paper, we describe the process of creating the state benchmark and present research evidence showing strong relationships that link high levels of PYD to reduced levels of risk behaviors and increased levels of positive, healthy behaviors among Oregon youth. The creation of this benchmark allows better planning, development and monitoring of PYD programs by state agencies, schools and community partners. In addition, results reinforce the finding that the promotion of programs that boost one or more elements of PYD may help reduce risky behaviors and improve positive, healthy behaviors among adolescents.
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Murphy, John. "Expectation Losses, Negligent Omissions and the Tortious Duty of Care." Cambridge Law Journal 55, no. 1 (March 1996): 43–55. http://dx.doi.org/10.1017/s0008197300097725.
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In English law, the recovery of pure economic loss falls mainly within the province of the law of contract. Only in very limited circumstances does the law of tort provide for the recovery of such losses. As Cardozo C.J. explained in Ultramares Corporation v. Touched, tort is concerned not to permit “liability in an indeterminate amount, for an indeterminate time to an indeterminate class”. Notwithstanding this reticence, their Lordships' speeches, though not the final decision, in the seminal case of Hedley Byrne & Co. Ltd. v. Heller and Partners Ltd. provided a notable inroad into the rigidity of this stance. Since Hedley Byrne, the question has become, instead, how far, not if, pure economic loss is and should be recoverable in the law of negligence.
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Pyle, J., G. Farquharson, J. Gibson, D. Helgeson, and J. Towart. "The Beryl Field area: increasing production in a mature asset." Geological Society, London, Petroleum Geology Conference series 8, no. 1 (August 30, 2017): 507–23. http://dx.doi.org/10.1144/pgc8.32.
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AbstractThe Beryl Field is one of the largest oil fields in the UK Continental Shelf. Mobil commenced production in 1976 via the Beryl Alpha platform. Production peaked at approximately 200 000 BOE/day in 1993 before declining to around 50 000 BOE/day in 2012.Apache assumed operatorship in 2012 and, along with partners Shell, has arrested and reversed production decline on platform production through investment in 3D seismic data, drilling, workovers and improvements to operational efficiency. Redevelopment to date by the Beryl area partnership has focused on strategic wells across multiple play types and fields. These wells have realized an 88% success rate and have led to the delineation of additional, lower risk, drill locations. Drilling flexibility, a deep target inventory and effective partner relationships help to expedite the most valuable opportunities and maintain the drilling campaign.In the future, production growth is anticipated through cost-effective developments of new and existing near-field opportunities, including the recently discovered Callater Field with first oil planned in 2017.Three case studies will illustrate: the importance of structural compartmentalization in under-developed fields; the opportunities remaining in mature fields as a result of historical field management practices; and the value of near and new field opportunities for extending field life.
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Gilbert, David. "Rethinking engagement." BJPsych Bulletin 43, no. 1 (August 29, 2018): 4–7. http://dx.doi.org/10.1192/bjb.2018.55.
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People affected by health conditions bring insights and wisdom to transform healthcare – ‘jewels from the caves of suffering'. Yet traditional patient and public engagement relies on (child–parent) feedback or (adolescent–parent) ‘representative' approaches that fail to value this expertise and buffers patients' influence. This editorial outlines the emergence of ‘patient leadership' and work in the Sussex Musculoskeletal Partnership, its patient director (the first such role in the National Health Service) and a group of patient/carer partners, who are becoming equal partners in decision-making helping to reframe problems, generate insight, shift dynamics and change practice within improvement and governance work.Declaration of interestDavid Gilbert is Director of InHealth Associates Ltd, a small consultancy organisation that supports patient and public engagement.
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Poudel, Kritika, Naomi Sumi, and Rika Yano. "Impact of Peer-Led Cancer Education Program on Knowledge, Health Beliefs, Practice, and Self-Esteem among Pairs of Nepalese High-School Students and Their Knowledge-Sharing Partners." Healthcare 9, no. 1 (January 11, 2021): 64. http://dx.doi.org/10.3390/healthcare9010064.
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Raising cancer awareness among adolescents can increase their confidence in identifying cancer symptoms and develop healthy habits. This study tested the effectiveness of cancer education based on a new model among high schoolers. A non-randomized control group pre-post-test design study was conducted among 313 pairs of adolescent students and their knowledge-sharing partners in Lalitpur, Nepal. A baseline test was conducted before the education program, and it was followed up at two weeks and three months. Results were measured using a chi-square test, binary logistic regression, and a two-way repeated-measures ANOVA. There was a significant interaction effect of intervention and time on students’ knowledge, beliefs, self-esteem, and practice, along with a change in some scores of knowledge-sharing partners. Joint assignment supported the idea of diffusion of information within the family and in the neighborhood. The peer group discussion could encourage active learning and help students to participate visibly in problem-solving and reflecting more sustainably. Time constraints, lack of human resources, and support groups, might limit this program’s usage; however, preparing guidelines, and connecting communities, organizations, hospitals, volunteer health workers, and survivors can help make it more sustainable and approachable.
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Poudel, Kritika, Naomi Sumi, and Rika Yano. "Impact of Peer-Led Cancer Education Program on Knowledge, Health Beliefs, Practice, and Self-Esteem Among Pairs of Nepalese High-School Students and Their Knowledge-Sharing Partners." Healthcare 9, no. 1 (January 11, 2021): 64. http://dx.doi.org/10.3390/healthcare9010064.
Full textAbstract:
Raising cancer awareness among adolescents can increase their confidence in identifying cancer symptoms and develop healthy habits. This study tested the effectiveness of cancer education based on a new model among high schoolers. A non-randomized control group pre-post-test design study was conducted among 313 pairs of adolescent students and their knowledge-sharing partners in Lalitpur, Nepal. A baseline test was conducted before the education program, and it was followed up at two weeks and three months. Results were measured using a chi-square test, binary logistic regression, and a two-way repeated-measures ANOVA. There was a significant interaction effect of intervention and time on students’ knowledge, beliefs, self-esteem, and practice, along with a change in some scores of knowledge-sharing partners. Joint assignment supported the idea of diffusion of information within the family and in the neighborhood. The peer group discussion could encourage active learning and help students to participate visibly in problem-solving and reflecting more sustainably. Time constraints, lack of human resources, and support groups, might limit this program’s usage; however, preparing guidelines, and connecting communities, organizations, hospitals, volunteer health workers, and survivors can help make it more sustainable and approachable.
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van der Burg, Max Post, Catherine Cullinane Thomas, Tracy Holcombe, and Richard D. Nelson. "Benefits and Limitations of Using Decision-Analytic Tools to Assess Uncertainty and Prioritize Landscape Conservation Cooperative Information Needs." Journal of Fish and Wildlife Management 7, no. 1 (March 1, 2016): 280–90. http://dx.doi.org/10.3996/032015-jfwm-023.
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Abstract The Landscape Conservation Cooperatives (LCCs) are a network of partnerships throughout North America that are tasked with integrating science and management to support more effective delivery of conservation at a landscape scale. To achieve this integration, some LCCs have adopted the approach of providing their partners with better scientific information in an effort to facilitate more efficient and coordinated conservation decisions. Taking this approach has led many LCCs to begin funding research to provide the information for improved decision making. To ensure that funding goes to research projects with the highest likelihood of leading to more integrated broad-scale conservation, some LCCs have also developed approaches for prioritizing which information needs will be of most benefit to their partnerships. We describe two case studies in which decision-analytic tools were used to quantitatively assess the relative importance of information for decisions made by partners in the Plains and Prairie Potholes LCC. The results of the case studies point toward a few valuable lessons in terms of using these tools with LCCs. Decision-analytic tools tend to help shift focus away from research-oriented discussions and toward discussions about how information is used in making better decisions. However, many technical experts do not have enough knowledge about decision-making contexts to fully inform the latter type of discussion. When assessed in the right decision context, however, decision analyses can point out where uncertainties actually affect optimal decisions and where they do not. This helps technical experts understand that not all research is valuable in improving decision making. Perhaps most important, our results suggest that decision-analytic tools may be more useful for LCCs as a way of developing integrated objectives for coordinating partner decisions across the landscape, rather than simply ranking research priorities.
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Kuschel, Katherina, and María-Teresa Lepeley. "Copreneurial women in start-ups." Academia Revista Latinoamericana de Administración 29, no. 2 (June 6, 2016): 181–97. http://dx.doi.org/10.1108/arla-08-2015-0231.
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Purpose Latin American investors are commonly suspicious of investing in copreneurial ventures (a male and female couple, integrated as a working team) and show even higher levels of uncertainty when the start-ups are led by a female founder. The purpose of this paper is to address issues related to women as leaders in copreneurial tech ventures and analyses whether these ventures are growth-oriented or conform to limited partnerships aimed primarily to meet their living standards. Design/methodology/approach A qualitative, inductive and constructive approach was required for addressing the research question. Three copreneurial women and two divorced copreneurs were interviewed. A grounded theory approach was used to analyze data and emerging themes. Findings Copreneurial teams that work in the technology industry have similar and complementary levels of education and skills development. After three years working together, each partner becomes well aware of mutual skills and strengths. This allows them to define their respective roles. Both divide work and family, and have developed a level of mutual trust and commitment that is essential to move forward. Commonly they show workaholic tendencies with a high rational underpinning. All of these factors strengthen collaboration and in many instances this business liaison can remain intact despite a breakdown in the partners’ sentimental relationship. Additional findings show that their growth orientation takes multiple structures. Practical implications This study provides information that can help investors make decisions to support copreneurial teams that optimize from the use of diverse talents of female and male partners. Originality/value Although representing an increasingly common type of start-up team, copreneurship in technology has not yet capture much attention of scholars as case study in family business research.
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Stanley, Talmage, and Stephen Fisher. "Partners, Neighbors, and Friends: The Practice of a Place-Based Education." Practicing Anthropology 23, no. 2 (April 1, 2001): 19–23. http://dx.doi.org/10.17730/praa.23.2.f2j7714442238q77.
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At Emory and Henry College, our vision for a place-based education integrating service with learning led in 1996, to the approval of the creation of a new major in Public Policy and Community Service. A rigorous and interdisciplinary service learning major, all of its courses are designed to help students better understand the impact of local, regional, national, and global structures and institutions on social change. As the curriculum evolves, we are institutionalizing in it a systematic study of several primary conceptual themes: citizenship, service, religion, public ethics, cultural diversity, public policy, place-based politics, social justice, and social change. The program aims to empower students by enabling them 110t only to understand critically the necessity and processes of social change but also to become agents of change in Southwest Virginia, Appalachia, and beyond, while they are students.
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Moss, Melissa A. "The Escambia Project: An Experiment in Community-Led Legal Design." Design Issues 36, no. 3 (June 2020): 45–60. http://dx.doi.org/10.1162/desi_a_00603.
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This article shares observations made during an experimental community-led design project undertaken to identify promising new solutions for civil justice services which low-income Escambia County residents could easily use. The Florida Bar Foundation-funded project generated three new initiatives that were prototyped, filed tested, and prepared for continuation. The Escambia Project ultimately engaged more than 100 community members and relied on the support of dozens of local volunteers and organizations. All three initiatives have been adopted by the local legal aid program partner or the community and continue in some form. The article also contains lessons learned and recommendations for how community-led participatory design could help transform the justice system.
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Luttik, Marie Louise, Tiny Jaarsma, Jan G. P. Tijssen, Dirk J. van Veldhuisen, and Robbert Sanderman. "The Objective Burden in Partners of Heart Failure Patients; Development and Initial Validation of the Dutch Objective Burden Inventory." European Journal of Cardiovascular Nursing 7, no. 1 (March 2008): 3–9. http://dx.doi.org/10.1016/j.ejcnurse.2007.02.005.
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Background: Measures on objective caregiver burden in partners of Heart Failure patients are hardly available and never include HF specific aspects. Aim: The main objective of our study was to develop an inventory that assesses the objective caregiver burden of partners of HF patients, including the full range of potential care giving demands. Methods: To develop the inventory, six domains of caregiving demands were identified. Items for the domains were generated from the literature, expert opinion and existing scales. The original 50-items self-report inventory was administered to 321 partners of HF patients. Demographic data of HF partners were collected by questionnaire. Clinical data of the HF patients were collected by chart review. Results: Component analysis led to exclusion of 12 original items and to a meaningful four-factor solution with a total explained variance of 43%. The components reflected four different kinds of care giving tasks; personal care, emotional, motivational and practical (treatment related) support. They demonstrated good internal consistency and initial validity was supported by a pattern of meaningful associations with external variables. Conclusion: The Objective Burden Inventory is a promising inventory to assess objective care giving tasks performed by HF partners, including emotional and motivational support. It provides information on the caregiver situation that may help to develop effective interventions.
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Eaton, Leslie G., and David C. Funder. "The creation and consequences of the social world: an interactional analysis of extraversion." European Journal of Personality 17, no. 5 (September 2003): 375–95. http://dx.doi.org/10.1002/per.477.
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Seventy‐six previously unacquainted, opposite‐sex pairs of undergraduate participants engaged in a 5 min videotaped interaction, then provided their mutual impressions. Research assistants coded 64 behaviours from the videotapes; these ratings were combined into behavioural factors. Participants provided self‐descriptions of personality and were described by two acquaintances. Path analyses indicated that targets extraversion was associated with their behavioural involvement, which in turn was associated with partners subsequent ratings of their personality. Targets interpersonal positive affectivity was associated with their partners extraversion. Similar patterns of behavioural associations were found in relation to self‐reported, partner‐reported, and acquaintance‐reported extraversion. These results demonstrate how extraverts may create a positive social environment through their own positivity and by creating a social press for positivity in return. Copyright © 2003 John Wiley & Sons, Ltd.
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Neyer, Franz J., and Daniel Voigt. "Personality and social network effects on romantic relationships: a dyadic approach." European Journal of Personality 18, no. 4 (June 2004): 279–99. http://dx.doi.org/10.1002/per.519.
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The quality of romantic relationships and their associations with both partners' personality traits and social networks were studied in 100 younger couples. The similarity of partners was modest with respect to personality traits, and moderate to large with respect to the perceived quality of the partner relationship and their social networks. While similarity in personality was unrelated to relationship quality, dyadic analyses showed that one's perceived quality of relationship was better predicted by one's own personality (i.e. actor effects) than by the personality of one's partner (i.e. partner effects). Moreover, relationship quality could to some extent be predicted by the quality of the social network once the personality traits of each partner were controlled. Results are discussed from a transactional view of personality and relationships. Copyright © 2004 John Wiley & Sons, Ltd.
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Yoon, Byungun, and Bomi Song. "A systematic approach of partner selection for open innovation." Industrial Management & Data Systems 114, no. 7 (August 5, 2014): 1068–93. http://dx.doi.org/10.1108/imds-03-2014-0086.
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Purpose – The purpose of this paper is to propose a systematic approach to exploring potential partners for open innovation in order to facilitate the process of technological collaboration. Design/methodology/approach – The proposed approach utilizes patent information that is considered the most effective data to investigate innovation activities by applying morphology analysis (MA) and generative topology map (GTM) to the process to identify the configurations of technologies and visualize the collected patent information. In particular, diverse informative indices can assist researchers in deriving appropriate partners for technological cooperation. Findings – The hybrid approach that combines MA, GTM, and indices is useful to discover technological opportunity, identify necessary technologies and explore potential partners. The systematic process can overcome the limitations of existing approaches that depend on the insights and strategic decisions of top management, reflect a superficial relationship among firms and mostly fail to consider both theoretical and practical approaches to retrieve potential partners. Practical implications – The results of this paper will help practitioners, academic researchers, and policy makers link a pair of partners who can maximize the synergy of collaboration in a systematic manner. The proposed approach is illustrated to show the validity of the process with a case of light emitting diode (LED) technology. In addition, the social cost for collaboration can be reduced by applying the proposed approach in open innovation. Originality/value – This paper tackles the important issue of exploring appropriate partners by applying a systematic approach that utilizes text mining, MA and GTM because existing research mostly deals with ad-hoc processes. The proposed approach utilizes multiple methodologies of data mining and technology forecasting to derive promising technology areas in a systematic manner and then employs critical indices to explore proper partners. Thus, this approach considers both quantitative and qualitative methodologies to suggest a sophisticated tool for successful open innovation. Moreover, a real case – LED case was illustrated to demonstrate that the proposed approach can be employed to implement technological cooperation.
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Poll, Jordan, Ayse Buyktur, Aalap Doshi, Linde Huang, Tricia Piechowski, Meghan Spiroff, and Erica Marsh. "4455 Advancing the Science of Community Engagement with Human-Centered Design." Journal of Clinical and Translational Science 4, s1 (June 2020): 77–78. http://dx.doi.org/10.1017/cts.2020.252.
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OBJECTIVES/GOALS: To describe how the Community Engagement (CE) Program at the Michigan Institute for Clinical & Health Research (MICHR), a Clinical & Translational Science Award (CTSA) site at the University of Michigan, is adopting human-centered design (HCD) to advance the science of community engagement in translational research and CE’s programmatic efforts. METHODS/STUDY POPULATION: The MICHR CE Program supports academic-community partnerships to transform translational research across the state of Michigan. As the team aims to better engage partners to help guide the direction of their work, CE is collaborating with MICHR’s Design and Innovation Core to incorporate human-centered design (HCD). HCD is an approach that prioritizes the needs, values, and perspectives of direct users during the creation of a new product or service. The MICHR team created interactive HCD activities for two statewide retreats to elicit feedback from community and academic members on ways to enhance community-engaged research (CEnR). Retreat participants worked on a variety of problems, such as barriers to partnering and defining impact for CEnR. These activities generated authentic, contextual, and multi-view data captured in various artifacts for systematic analysis. RESULTS/ANTICIPATED RESULTS: In the first retreat, a HCD activity had participants reflect on their own barriers to partnering in research and potential solutions. In the second retreat, an HCD activity facilitated participants interviewing each other on their views of the impact in CEnR. Results from the first activity identified a set of common barriers to CEnR, some related to partnership formation, communication, and partner equity, among others. These led the CE Program to specific programmatic efforts, such as designing a statewide partnership platform, hiring a communication program manager, and sponsoring community partners to join national conferences. The second retreat activity produced rich data to identify overlaps between different perspectives to inform how impact can be defined and measured in CEnR. DISCUSSION/SIGNIFICANCE OF IMPACT: HCD activities provide means to include community and academic members in the science of CEnR. They allow systematic ways to gather information directly from the diverse set of current or prospective partners of community engagement programs about their needs, experiences, and values, which can be translated to programmatic innovation.
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Gulbis, Ivo, and Sanda Geipele. "Social Partner Involvement in Latvia Special Economic Zones." Baltic Journal of Real Estate Economics and Construction Management 4, no. 1 (November 1, 2016): 145–52. http://dx.doi.org/10.1515/bjreecm-2016-0011.
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Abstract With increasing global competitiveness, countries must have instruments to attract and keep businesses. One way involves attracting a core of foreign investors with the help of special economic zones (SEZs) and integrating them in local economy, causing industrial clustering. The aim of this research is to lay the groundwork for a comprehensive analysis of clustering potential in Latvia via its special economic zones. The empirical research relied on survey results conducted among 27 business associations with the combined member count of over one thousand businesses, operating in 12 broad fields. Initial results gathered from the 24 organizations that responded to the interview questions show that there is a very low degree of involvement in the SEZ by various social partners. This shows that something has gone awry in the way SEZ operate in Latvia and has led to a lot of missed opportunities from both sides.
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Kurnianto, Agung Made, Tantri Yanuar Rahmat Syah, Semerdanta Pusaka, and Dadan Ramdhani. "Marketing Strategy on The Project Planning of Retail Business for Garage Shop." International Journal of Multicultural and Multireligious Understanding 6, no. 1 (February 24, 2019): 217. http://dx.doi.org/10.18415/ijmmu.v6i1.513.
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Garage Shop, Ltd is a distribution company of all types of goods for the needs of cooperatives located in Tangerang which has a mission of maintaining customer satisfaction, providing an easy shopping process for cooperatives and participating in developing the country to advance the development of cooperatives. The background of the establishment of this business is to provide convenience for cooperatives in obtaining goods, facilitate cooperatives to manage and record the amount of goods, encourage cooperatives to be more advanced and to accommodate the desires of consumers who cannot shop on credit because they do not have a Garage Shop, Ltd for credit card, which concentrate on distributing goods for the needs of cooperatives that will be at the start of the cooperative members, in the early stages the Garage Shop, Ltd Company will start up in Tangerang Regency, Banten Province. In the operational process, the Garage Shop, Ltd company will cooperate with non-banking financial institutions. Garage Shop, Ltd needs funds for this business plan of around Rp. 2.5 billion, with working capital as much as 27% of the total capital while for capital expenditure and initial capital amounting to 73% of the total capital. The plan for funding capital will be 80% from the founder and 20% from the other party. The company maintains a gross profit of around 57% of first-year sales with 270 cooperative partners, with a return on investment (payback period) in year 1 of the 10th month with a Return of Investment (ROI) of 21.28%.
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Soleimanpour, Samira, Claire Brindis, Sara Geierstanger, Spenta Kandawalla, and Tamar Kurlaender. "Incorporating Youth-Led Community Participatory Research into School Health Center Programs and Policies." Public Health Reports 123, no. 6 (November 2008): 709–16. http://dx.doi.org/10.1177/003335490812300607.
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Training adolescents as student researchers is a strategy that can improve the delivery of care at school-based health centers (SBHCs) and significantly shift school health policies impacting students. From 2003 to 2006, the University of California, San Francisco, in partnership with Youth In Focus, implemented a participatory student research project to enhance the existing evaluation of the Alameda County SBHC Coalition and its participating clinic members, and to help develop and implement school health policies. Providing opportunities and training that enabled youth to identify and research the health needs of their peers, as well as advocate for improvements in SBHCs based on their research findings, represents an exciting youth development strategy. This article describes the role the youth played, how their adult partners supported their work, and the impact that their efforts had on the SBHCs and school health programming and policies in the areas of condom accessibility and mental health services.
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Muise, Jennifer L., and Paul R. Mackey. "Projects “Journey” and “Sunset” build connections for positive community impact." Journal of Community Safety and Well-Being 2, no. 1 (March 17, 2017): 29. http://dx.doi.org/10.35502/jcswb.37.
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In 2011, the Office of the Chief Coroner for Ontario released the Death Review of the Youth Suicides at Pikangikum First Nation, 2006-2008 following an alarmingly high number of youth suicides that occurred in that community. Persistent social, health, infrastructure, economic, capacity, and governance deficits that exist contribute to vulnerability and atrisk behaviours among youth including crime, substance abuse, and suicide. The Ontario Provincial Police (OPP) sought ways and means to work to address these challenges in collaboration with communities. After securing funding support through Public Safety Canada, the OPP implemented an experiential youth development program called Project Journey, modelled after Project Venture, a program from the United States specifically designed for at-risk Indigenous youth. So promising are the results from Project Journey that a sister program, Project Sunset, came into being to help expand the proactive work with community partners. These OPP-led programs help address the root causes of youth crime, social disorder, and crisis. At the same time, they support relationship-building and community engagement, and empower individuals and community partners to take positive action for sustainable change.
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Yen, Benjamin, Ali Farhoomand, and Pauline Ng. "Constructing an E-Supply Chain at Eastman Chemical Company." Journal of Information Technology 19, no. 2 (June 2004): 93–107. http://dx.doi.org/10.1057/palgrave.jit.2000011.
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Craig Knight, Asia Pacific Digital Business and Customer Services Manager of Eastman Chemical Company, was given a mandate to sell Eastman's philosophy for an integrated electronic supply chain, otherwise known as the Integrated System Solution (ISS), to its business partners in the region, and to encourage adoption. Having invested in a state-of-the-art technical architecture that would support interconnectivity with all parties along the supply chain, Eastman was keen to realise the full benefits to be gained from an integrated e-supply chain on a global scale. Following numerous rounds of discussion with key business partners in the Asia Pacific region, some progress had been made. Nagase & Co., Ltd. of Japan had agreed to adopt ISS connections with Eastman, but had some reservations regarding the extent of integration. Although the benefits of integration were proven, suppliers, customers, distributors and other interested parties were faced with numerous limitations and considerations that would have significant implications on their established business processes and even the shaping of their corporate strategy. Adoption was not a simple choice. Craig understood these shortcomings and was making every effort to ease the adoption process by identifying the longer-term benefits to Nagase and other business partners of applying XML technology to their businesses.