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Dissertations / Theses on the topic 'Heart – Differentiation'

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1

Litster, Caroline Elizabeth. "Heart rate, heart rate variability, electrodermal activity and the differentiation-of-deception /." Title page, table of contents and abstract only, 2002. http://web4.library.adelaide.edu.au/theses/09SSPS/09sspsl7769.pdf.

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2

Hinds, Heather C. "Evaluating terminal differentiation of porcine valvular interstitial cells in vitro." Link to electronic thesis, 2006. http://www.wpi.edu/Pubs/ETD/Available/etd-050506-113014/.

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3

O'Brien, Meghan M. "A pilot proteomic analysis : the study of P19 cells in cardiac differentiation /." Connect to resource online, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1229374725.

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4

Buccini, Stephanie M. "Cardiogenic differentiation of induced pluripotent stem cells for regeneration of the ischemic heart." University of Cincinnati / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1382373160.

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5

Younce, Craig. "Zinc-Finger Protein MCPIP in Cell Death and Differentiation." Doctoral diss., University of Central Florida, 2009. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2279.

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Monocyte chemotactic protein-1 (MCP-1) plays a critical role in the development of cardiovascular diseases. How MCP-1 contributes to the development of heart disease is not understood. We present evidence that MCP-1 causes death in cardiac myoblasts, H9c2 by inducing oxidative stress, ER stress and autophagy via a novel Zn-finger protein, MCP-1 induced protein (MCPIP). MCPIP expression caused cell death and knockdown of MCPIP, attenuated MCP-1 induced cell death. Expression of MCPIP resulted in induction of iNOS and production of reactive oxygen (ROS). It caused induction of NADPH oxidase subu
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6

Wei, Wenjie, and 魏闻捷. "Calcium signaling in the cardiac differentiation of mouse embryonic stem cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B49617862.

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  Intracellular Ca2+ mobilization via secondary messengers modulates multiple cell functions. Cyclic Adenosine 5’-Diphosphate-Ribose (cADPR) is one of the most well recognized endogenous Ca2+ mobilizing messengers. In mammalian, cADPR is mainly formed by CD38, a multi-functional enzyme, from nicotinamide adenine dinucleotide (NAD). It has previously been shown that the cADPR/CD38/Ca2+pathway mediates many cardiac functions, such as regulating the excitation-contraction coupling in cardiac myocytes and modulating the Ca2+ homeostasis during the ischemia injury of the heart. Thus it is reasonab
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7

Chau, Dinh Le Mary. "Role of Notch1 in Cardiac Cell Differentiation and Migration: A Dissertation." eScholarship@UMMS, 2007. https://escholarship.umassmed.edu/gsbs_diss/338.

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The cardiac conduction system is responsible for maintaining and orchestrating the rhythmic contractions of the heart. Results from lineage tracing studies indicate that precursor cells in the ventricles give rise to both cardiac muscle and conduction cells. Using chick embryonic hearts, we have found that Notch signaling plays an important role in the differentiation of cardiac muscle and conduction cell lineages in the ventricles. Notch1 expression coincides with a conduction marker at early stages of conduction system development. Mis-expression of constitutively active Notch1 (NIC) in earl
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8

Maliken, Bryan D. B. A. "Gata4-Dependent Differentiation of c-Kit+ Derived Endothelial Cells Underlies Artefactual Cardiomyocyte Regeneration in the Heart." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1535375861364685.

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9

Huang, Tianfang. "Mechanism of Arsenical Toxicity on TGFβ Signaling and Genetic Regulation During Cardiac Progenitor Cell Differentiation". Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/556428.

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Low to moderate level of chronic arsenic exposure contributes to cardiovascular ailments including heart disease and aneurysms. Current research on the etiology and progression of cardiovascular disease focuses mainly on adult which fails to capture the developmental origins of cardiovascular disease. Thus, disruption in morphogenetic events during early development may initiate and pattern the molecular programming of cardiovascular ailments in adulthood. A major contributor to ischemic heart pathologies is coronary artery disease, however the influences by environmental arsenic in this disea
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10

Momtahan, Nima. "Extracellular Matrix from Whole Porcine Heart Decellularization for Cardiac Tissue Engineering." BYU ScholarsArchive, 2016. https://scholarsarchive.byu.edu/etd/6225.

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Heart failure is one of the leading causes of death in the United States. Every year in the United States, more than 800,000 people are diagnosed with heart failure and more than 375,000 people die from heart disease. Current therapies such as heart transplants and bioartificial hearts are helpful, but not optimal. Decellularization of porcine whole hearts followed by recellularization with patient-specific human cells may provide the ultimate solution for patients with heart failure. Great progress has been made in the development of efficient processes for decellularization, and the design o
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11

Sargent, Carolyn Yeago. "Effects of hydrodynamic culture on embryonic stem cell differentiation: cardiogenic modulation." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/34710.

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Stem and progenitor cells are an attractive cell source for the treatment of degenerative diseases due to their potential to differentiate into multiple cell types and provide large cell yields. Thus far, however, clinical applications have been limited due to inefficient differentiation into desired cell types with sufficient yields for adequate tissue repair and regeneration. The ability to spontaneously aggregate in suspension makes embryonic stem cells (ESCs) amenable to large-scale culture techniques for the production of large yields of differentiating cell spheroids (termed embryoid b
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12

Maddali, Kamala Kalyani. "A mandatory requirement of PKC-[delta] in testosterone regulated coronary smooth muscle cell differentiation, proliferation and apoptosis /." Free to MU Campus, others may purchase, 2005. http://proquest.umi.com/pqdweb?did=1232392431&sid=1&Fmt=2&clientId=45247&RQT=309&VName=PQD.

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13

Henje, Blom Eva. "Anxiety and depression in adolescent females autonomic regulation and differentiation /." Stockholm, 2010. http://diss.kib.ki.se/2010/978-91-7409-807-5/.

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14

SHELTON, ELAINE L. "Thr roles of Twist1 and Tbx20 in endocardial cell proliferation, migration, and differentiation during endocardial cushion development." University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1212062811.

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15

Farouz, Yohan. "Designing biomaterials for controlled cardiac stem cell differentiation and enhanced cell therapy in the treatment of congestive heart failure." Thesis, Sorbonne Paris Cité, 2015. http://www.theses.fr/2015USPCB114/document.

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La thérapie cellulaire se positionne comme une stratégie prometteuse pour inciter le cœur infarci à se régénérer. A cet effet, des études récentes placent des espoirs considérables dans l’utilisation des cellules souches embryonnaires et notre laboratoire a déjà démontré comment les différencier en progéniteurs cardiovasculaires, un type de précurseurs cellulaires qui ne peut aboutir qu’à la formation de cardiomyocytes, de cellules endothéliales ou de cellules de muscles lisses. Cet engagement précoce réduit leur capacité de prolifération anarchique et en même temps leur permet de rester suffi
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16

Olson, Erik Ryan. "Signaling mechanisms controlling the proliferation and differentiation of cardiac fibroblasts." [Kent, Ohio] : Kent State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=kent1162230649.

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Thesis (Ph.D.)--Kent State University, 2006.<br>Title from PDF t.p. (viewed Jan. 11, 2007 ) Advisor: J Gary Meszaros. Keywords: cardiac fibroblast, angiotensin II, fibrosis, MAPK Includes bibliographical references (p. 150-168).
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17

Swinarski, Marie. "PCP-driven cardiac remodeling couples changes in actomyosin tension with myocyte differentiation." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2017. http://dx.doi.org/10.18452/17775.

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Im Zuge der frühen embryonalen Herzentwicklung entstehen ausgehend von einem einfachen Herzschlauch zwei deutlich voneinander getrennte Herzkammern. Die Kardiomyozyten des Atriums und Ventrikels weisen spezifische Eigenschaften auf, die sich morphologisch wie auch funktionell auf das Herz auswirken. Veränderungen in der Gewebsarchitektur werden hauptsächlich durch Zellinterkalation und kollektive Zellmigration erreicht. Viele Studien zeigen, dass der Wnt/PCP-Signalweg eine essentielle Rolle in der Regulation dieser Bewegungen einnimmt. Die Daten dieser Studie belegen, dass die nicht-kanonische
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18

Self, Magdalen Romany Rowen. "Repair of a wounded heart : an investigation into the effects of aggregation on the differentiation of stem cells to cardiomyocytes." Thesis, University of Nottingham, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.523583.

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19

Di, Guglielmo Claudia. "Biotechnological approaches to cardiac differentiation of human induced pluripotent stem cells." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/385921.

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The heart can be considered the most important organ of our body, as it supplies nutrients to all the cells. When affected from injuries or diseases, the heart function is hampered, as the damaged area is substituted by a fibrotic scar instead of functional tissue. Understanding the mechanisms leading to heart failure and finding a cure for cardiac diseases represents a major challenge of modern medicine, since they are the leading cause of death and disability in Western world. Being the heart a vital organ it is difficult to have access to its cells, especially in humans. In order to model i
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20

Moncada, Diaz Silvia Juliana. "Repopulation and Stimulation of Porcine Cardiac Extracellular Matrix to Create Engineered Heart Patches." BYU ScholarsArchive, 2018. https://scholarsarchive.byu.edu/etd/8806.

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Heart failure is the main cause of death for both men and women in the United States. The only proven treatment for patients with heart failure is heart transplantation. The goal of this research is to create patches of tissue that could mimic the function of the native heart to repair the damaged portions of the heart. In this study, whole porcine hearts were decellularized to create a 3D construct that was recellularized with cardiomyocytes (CM) differentiated from human induced pluripotent stem (IPS) cells. At day 4 of differentiation, IPS-derived CMs were implanted onto cardiac extracellul
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21

Zakariyah, Abeer. "The Characterization of a Human Disease-Associated Mutation Nkx2.5 R142C Using In vitro and In vivo Models." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/35817.

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Nkx2.5 is a cardiac transcription factor that plays a critical role in heart development. In humans, heterozygous mutations in the NKX2.5 gene result in congenital heart defects (CHDs), but the molecular mechanisms by which these mutations cause the defects are still unknown. NKX2.5 R142C is a mutation that is found to be associated with atrial septal defect and atrioventricular block in 13 patients from one family. The R142C mutation is located within both the DNA-binding domain and the nuclear localization sequence of NKX2.5 protein. The pathogenesis of CHDs in humans with R142C point mutati
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22

Silva, Daniela Nascimento. "Isolamento e caracterização de células-tronco obtidas de corações de camundongos adultos." reponame:Repositório Institucional da FIOCRUZ, 2014. https://www.arca.fiocruz.br/handle/icict/8001.

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Submitted by Ana Maria Fiscina Sampaio (fiscina@bahia.fiocruz.br) on 2014-07-21T17:48:02Z No. of bitstreams: 1 Daniela Nascimento Siilva, Isolamento e caracterização... 2014a.pdf: 1250843 bytes, checksum: 1e4824ac04c822156d7a910d485dbc6b (MD5)<br>Made available in DSpace on 2014-07-21T17:48:02Z (GMT). No. of bitstreams: 1 Daniela Nascimento Siilva, Isolamento e caracterização... 2014a.pdf: 1250843 bytes, checksum: 1e4824ac04c822156d7a910d485dbc6b (MD5) Previous issue date: 2014<br>Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil<br>O uso de células-tronco represe
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23

Bondue, Antoine. "Mesp1 functions in multipotent cardiovascular progenitor specification." Doctoral thesis, Universite Libre de Bruxelles, 2009. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210319.

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During embryonic development, multipotent cardiovascular progenitor cells (MCPs) are specified from early mesoderm. Although the core cardiac transcriptional machinery acting during cardiac cell differentiation is relatively well known, the molecular mechanism acting upstream of these cardiac transcriptional factors, and promoting cardiac progenitor specification from early mesoderm remains poorly understood. We used embryonic stem cell (ESC) differentiation as a model to dissect the molecular mechanisms implicated in cardiovascular progenitor specification. Using ESCs, in which gene expressio
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24

Paiva, Solenne. "Facteurs environnementaux et épigénétiques impliqués dans la différenciation cardiaque de cellules souches humaines pluripotentes induites MiRroring the Multiple Potentials of MicroRNAs in Acute Myocardial Infarction Acellular therapeutic approach for heart failure: in vitro production of extracellular vesicles from human cardiovascular progenitors." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS457.

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L’objectif de cette thèse a été d’évaluer certains paramètres physiques et épigénétiques impliqués dans la différenciation cardiaque de cellules souches humaines pluripotentes induites. Un premier paramètre physique souvent sous-évalué a été étudié, celui de la rigidité. Classiquement, les cellules souches sont cultivées et adaptées à des rigidités in vitro allant de 1-10 GPa très éloignées des valeurs physiologiques, de l’ordre du kPa. L’impact de support de culture à 3, 12 et 25 kPa a été évalué sur les cellules souches initiales. Les résultats montrent que des rigidités inférieures à 25 kPa
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25

Watson, Andrea. "Heat shock proteins in leukaemia cell differentiation and cell death." Thesis, Aston University, 1990. http://publications.aston.ac.uk/12533/.

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When HL60 cells were induced to differentiate to granulocyte-like cells with the agents N-methylformamide and tunicamycin an concentrations marginally below those which were cytotoxic, there was a decrease in the synthesis of the glucose- regulated proteins which preceded the expression of markers of a differentiated phenotype. There was a transient increase in the amount of hsp70 after 36 hours in NMF treated cells but in differentiated cells negligible amounts were detected. Inducers which were known to modulate hsp70 such as azetadine carboxylic acid did not induce differentiation suggestin
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Rao, Srinivas Venkateswarlu. "Examination of the role of porcine heat shock protein during adipocyte differentiation /." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487757723995836.

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27

Doroodian, Paymon. "Overexpression of Differentiation and Greening-Like Alters Stress Response of Arabidopsis thaliana." Ohio University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1596227767908937.

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28

Stiening, Chad Michael. "GENOMIC REGULATION OF BOVINE MAMMARY EPITHELIAL CELL GROWTH AND DIFFERENTIATION." Diss., Tucson, Arizona : University of Arizona, 2005. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu%5Fetd%5F1252%5F1%5Fm.pdf&type=application/pdf.

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29

Guyette, Jacques Paul. "Conditioning of Mesenchymal Stem Cells Initiates Cardiogenic Differentiation and Increases Function in Infarcted Hearts." Digital WPI, 2012. https://digitalcommons.wpi.edu/etd-dissertations/32.

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Current treatment options are limited for patients with myocardial infarction or heart failure. Cellular cardiomyoplasty is a promising therapeutic strategy being investigated as a potential treatment, which aims to deliver exogenous cells to the infarcted heart, for the purpose of restoring healthy myocardial mass and mechanical cardiac function. While several cell types have been studied for this application, only bone marrow cells and human mesenchymal stem cells (hMSCs) have been shown to be safe and effective for improving cardiac function in clinical trials. In both human and animal s
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30

Hosie, Andrew. "Differentiating thermal from non-thermal eccrine sweating during exercise and heat stress." Access electronically, 2002. http://www.library.uow.edu.au/adt-NWU/public/adt-NWU20041105.114628/index.html.

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31

Haddad, Nisrine. "The effects of heat-shock and differentiation on nuclear structure/functions in mammalian cellular systems." Thesis, University of Ottawa (Canada), 2002. http://hdl.handle.net/10393/6292.

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The work delineated in this research thesis aims to achieve advances in understanding nuclear structure-function interrelationships. Two natural physiological processes---heat-shock and differentiation---have been used in order to provide a clearer understanding of the "big picture" that links structure and functions together. I have performed experiments using mild or severe heat-shock on HeLa S3 cells and I differentiated L6E9 myoblasts into skeletal muscle fibers. Microscopic and biochemical analysis were used in order to assess the effects of heat-shock and differentiation on nuclear morph
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32

Rusnak, Lauren Elizabeth. "Investigating Heat Shock Protein 70 as a Binding Partner of MK-STYX, and the Role of MK-STYX in Neuronal Differentiation." W&M ScholarWorks, 2013. https://scholarworks.wm.edu/etd/1539626944.

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33

Huber, Adrian Thomas. "Multi-organ non-invasive tissue characterization of fibrosis, adipose tissue, edema and inflammation with magnetic resonance (MR) imaging : applications to myocardium, skeletal muscle and liver interactions Cardiac MR strain: a noninvasive biomarker of fibro-fatty remodeling of the left atrial myocardium Comparison of MR T1 and T2 mapping parameters to characterize myocardial and skeletal muscle involvement in systemic Idiopathic Inflammatory Myopathy (IIM) Non-invasive differentiation of acute viral myocarditis and idiopathic inflammatory myopathy with cardiac involvement using magnetic resonance imaging T1 and T2 mapping CT predicts liver fibrosis: Prospective evaluation of morphology- and attenuationbased quantitative scores in routine portal venous abdominal scans." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS135.

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Cette thèse réalise une preuve de concept pour quantifier la déformation de l’oreillette gauche (OG) en IRM, ainsi que la relaxométrie IRM dans le myocarde, dans les muscles squelettiques et dans le foie. Grâce à l’interaction entre radiologues et ingénieurs, deux logiciels différents ont été développés, appliqués et validés pour l'analyse de la déformation myocardique multi-chambre et pour la cartographie quantitative du T1 multi-organes. La première publication a montré une forte corrélation de la déformation de l’OG, avec le degré de remplacement fibro-graisseux en histologie. Ce biomarqueu
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34

Mohammed, Sara Basher Taha [Verfasser]. "The Role of Heat Shock Protein 90 (HSP90) in the Transformation of Theileria annulata- infected Cells and the Parasite Stage Differentiation / Sara Basher Taha Mohammed." Berlin : Freie Universität Berlin, 2015. http://d-nb.info/1077478321/34.

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35

Raad, Farah. "Characterization and Application of Bioengineered Heart Muscle as a New Tool to Study Human Heart Development and Disease." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-002B-7C05-A.

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36

Lopes, Floro Kylie Biotechnology &amp Biomolecular Sciences Faculty of Science UNSW. "Dissecting the requirement for Cited2 during heart development and left-right patterning of the mouse embryo." 2007. http://handle.unsw.edu.au/1959.4/40531.

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Cited2 is a member of the Cited gene family, which has no homology to any other genes. It encodes a transcriptional co-factor that is expressed during early heart formation (cardiogenesis). Embryos lacking Cited2 display a range of cardiac defects including bilaterally identical atria, aortic arch abnormalities, rotation of the aorta and pulmonary artery, and malseptation of the cardiac chambers. The latter results in communication between the aorta and pulmonary artery, the aorta and both ventricles, and the atria and ventricles (with themselves and each other). Cardiogenesis is complex, and
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37

"Gene expression profiles in neonatal heart development and functional roles of calcyclin binding protein/Siah-interacting protein in terminal differentiation of cardiomyocytes." 2004. http://library.cuhk.edu.hk/record=b6073675.

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by Au Ka Wing.<br>"June 2004."<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2004.<br>Includes bibliographical references (p. 153-162).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Mode of access: World Wide Web.<br>Abstracts in English and Chinese.
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"Purification of cardiomyocytes derived from differentiated embryonic stem cells and study of the cytokines' effect on embryonic stem cell differentiation." 2008. http://library.cuhk.edu.hk/record=b5893596.

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Leung, Sze Lee Cecilia.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2008.<br>Includes bibliographical references (leaves 144-153).<br>Abstracts in English and Chinese.<br>Abstract --- p.i<br>Abstract in Chinese (摘要) --- p.iii<br>Acknowledgements --- p.v<br>Table of Content --- p.vi<br>Abbreviations --- p.xv<br>Chapter CHAPTER 1 --- INTRODUCTION<br>Chapter 1.1 --- Stem cells --- p.1<br>Chapter 1.1.1 --- Adult stem cells --- p.2<br>Chapter 1.1.2 --- Embryonic stem cells --- p.2<br>Chapter 1.1.3 --- Pros and cons of embryonic and adult stem cells --- p.5<br>Chapter 1.1.4 --- Hu
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"Role of reactive oxygen species (ROS) in cardiomyocyte differentiation of mouse embryonic stem cells." 2009. http://library.cuhk.edu.hk/record=b5894101.

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Law, Sau Kwan.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2009.<br>Includes bibliographical references (leaves 111-117).<br>Abstract also in Chinese.<br>Thesis Committee --- p.i<br>Acknowledgements --- p.ii<br>Contents --- p.iii<br>Abstract --- p.vii<br>論文摘要 --- p.x<br>Abbreviations --- p.xi<br>List of Figures --- p.xiii<br>List of Tables --- p.xxiii<br>Chapter CHAPTER ONE --- INTRODUCTION<br>Chapter 1.1 --- Embryonic Stem (ES) Cells<br>Chapter 1.1.1 --- Characteristics of ES Cells l<br>Chapter 1.1.2 --- Therapeutic Potential of ES Cells --- p.3<br>Chapter 1.1.3 --- Myocard
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40

"Mechanisms underlying the self-renewal characteristic and cardiac differentiation of mouse embryonic stem cells." 2009. http://library.cuhk.edu.hk/record=b5896594.

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Ng, Sze Ying.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2009.<br>Includes bibliographical references (leaves 110-124).<br>Abstract also in Chinese.<br>Thesis Committee --- p.i<br>Acknowledgements --- p.ii<br>Contents --- p.iii<br>Abstract --- p.vii<br>論文摘要 --- p.x<br>Abbreviations --- p.xi<br>List of Figures --- p.xiii<br>List of Tables --- p.xvii<br>Chapter CHAPTER ONE --- INTRODUCTION --- p.1<br>Chapter 1.1 --- Embryonic Stem Cells (ESCs) --- p.1<br>Chapter 1.1.1 --- What are ESCs and the characteristics of ESCs --- p.1<br>Chapter 1.1.1.1 --- Pluripotent markers --- p
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41

Lajiness, Jacquelyn D. "Shp2 deletion in post-migratory neural crest cells results in impaired cardiac sympathetic innervation." Thesis, 2014. http://hdl.handle.net/1805/5495.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Autonomic innervation of the heart begins in utero and continues during the neonatal phase of life. A balance between the sympathetic and parasympathetic arms of the autonomic nervous system is required to regulate heart rate as well as the force of each contraction. Our lab studies the development of sympathetic innervation of the early postnatal heart in a conditional knockout (cKO) of Src homology protein tyrosine phosphatase 2 (Shp2). Shp2 is a ubiquitously expressed non-receptor phosphatase involved in a variety of cellular func
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Lankeit, Mareike Katharina. "Neue Biomarker und Multimarkerstrategien für eine optimierte Risikostratifizierung von Patienten mit Lungenembolie." Doctoral thesis, 2010. http://hdl.handle.net/11858/00-1735-0000-0006-AF7C-A.

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43

Kang, Susey H. "Characterization of gene expression profiles during differentiation, lipopolysaccharide stimulation, and heat shock repression in human U937 monocyte cells." 2004. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=95285&T=F.

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Kaiser, Diana. "Der Einfluss mechanischer Last auf das Potential multipotenter adulter Keimbahnstammzellen zur kardialen Regeneration." Doctoral thesis, 2011. http://hdl.handle.net/11858/00-1735-0000-0006-ADEB-D.

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45

Montgomery, Amy. "Combining induced pluripotent stem cells and fibrin matrices for spinal cord injury repair." Thesis, 2014. http://hdl.handle.net/1828/5272.

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Spinal cord injuries result in permanent loss of motor function, leaving those affected with long term physical and financial burdens. Strategies for spinal cord injury repair must overcome unique challenges due to scar tissue that seals off the injury site, preventing regeneration. Tissue engineering can address these challenges with scaffolds that serve as cell- and drug-delivery tools, replacing damaged tissue while simultaneously addressing the inhibitory environment on a biochemical level. To advance this approach, the choice of cells, biomaterial matrix, and drug delivery system must be
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