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Dissertations / Theses on the topic 'Heart failure'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Williams, Michael Todd. "Heart Failure Readmission Strategy via Heart Failure Script." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/4189.

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Hospital administrators strive to reduce readmission and over use of the acute care setting for chronic health conditions. Historically hospitals have focused on readmission prevention strategies to improve the transition of patients from the hospital to the community and although the causes of a hospital readmission may span multiple providers along the continuum of care, the hospital is currently the only provider being penalized. The project facility implemented a readmission reduction strategy, Re-Engineered Discharge (Project RED), as a means to reduce readmissions and yet continued to ha

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2

MacDonald, Michael Ross. "Diabetes and heart failure." Thesis, University of Aberdeen, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.540346.

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The aim of this thesis was to explore the relationship between diabetes and heart failure, particularly focusing on epidemiology, aetiology and treatment. I was granted access to a number of databases that included patients with both diabetes and heart failure. Chapter one is a systematic review of the literature and each subsequent chapter describes an analysis of the individual patient cohorts. Chapters two to five examine the association of diabetes with both short and long-term outcomes in populations with different types of heart failure: out-patients with chronic heart failure; acute hea

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3

Elborn, Joseph Stuart. "Studies in heart failure." Thesis, Queen's University Belfast, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335936.

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4

Tan, Yu Ting. "Understanding diastolic heart failure." Thesis, University of Birmingham, 2013. http://etheses.bham.ac.uk//id/eprint/4392/.

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Many patients who present with symptoms of heart failure are found to have a normal left ventricular ejection fraction and therefore were labelled as having “diastolic heart failure” implying that the underlying pathophysiology is due to diastolic dysfunction alone. However, using a combination of echocardiographical techniques, a variety of abnormalities were found including reduced longitudinal function, impaired left ventricular twist and torsional dyssynchrony in systole leading to reduced and delayed untwisting, impaired suction and reduced early diastolic left ventricular filling not ful

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5

O'Donnell, Johanna. "Predicting heart failure deterioration." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:f7e51226-128b-44eb-8f6a-557f1d0c9a53.

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Chronic heart failure (HF) is a condition that affects more than 900,000 people in the UK. Mortality rates associated with the condition are high, with nearly 20% of patients dying within one year of diagnosis. Continuous monitoring and risk stratification can help identify patients at risk of deterioration and may consequently improve patients' likelihood of survival. Current repeated-measure risk stratification techniques for HF patients often rely on subjective perception of symptoms, such as breathlessness, and markers of fluid retention in the body (e.g. weight). Despite the common use of

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6

Huiskes, Bonita Louise. "Advanced heart failure in older women with heart failure and preserved systolic function." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3390049.

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7

Khand, Aleem U. "Arterial fibrillation and heart failure." Thesis, University of Glasgow, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288911.

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8

Gwadry-Sridhar, Femida Guyatt Gordon Henry. "Educating patients with heart failure /." [Hamilton, Ont.] : McMaster University, 2005.

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9

Wrigley, Benjamin J. "Monocyte subsets in heart failure." Thesis, University of Leicester, 2013. http://hdl.handle.net/2381/28383.

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Introduction: Monocytes play important roles in inflammation, thrombosis, angiogenesis and tissue repair and may contribute to the pathophysiology of heart failure (HF). Functional diversity is likely to stem from the presence of three distinct monocyte subsets, defined by flow cytometry (FC) as CD14++CD16-CCR2+ (Mon1), CD14++CD16+CCR2+ (Mon2) and CD14+CD16++CCR2- (Mon3). The aims of this thesis were to study the following parameters in patients with ischaemic HF: 1) monocyte subset numbers, 2) monocyte subset expression of surface receptors for inflammation, angiogenesis, cell adhesion molecu

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10

Narayan, Hafid. "Guanylin peptides in heart failure." Thesis, University of Leicester, 2013. http://hdl.handle.net/2381/28515.

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This study investigated the role of prouroguanylin (ProUGN) and proguanylin (ProGN), members of a novel class of peptides with natriuretic activity in heart failure (HF), a disorder of declining cardiac output associated with disturbed sodium and water homeostasis. The hypothesis was that ProUGN and ProGN activity is dysregulated in chronic and acute HF. Plasma ProUGN and ProGN were measured in 243 patients with chronic stable HF and plasma ProUGN and cGMP, an intracellular mediator of ProUGN activity, measured in 336 patients admitted to hospital with acute HF using immunoassays. ProUGN and c

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11

Cowburn, Pete James. "Endothelin and chronic heart failure." Thesis, University of Newcastle Upon Tyne, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324790.

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12

Cannon, Jane Ann. "Cognitive impairment in heart failure." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7839/.

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The clinical syndrome of heart failure is one of the leading causes of hospitalisation and mortality in older adults. Due to ageing of the general population and improved survival from cardiac disease the prevalence of heart failure is rising. Despite the fact that the majority of patients with heart failure are aged over 65 years old, many with multiple co-morbidities, the association between cognitive impairment and heart failure has received relatively little research interest compared to other aspects of cardiac disease. The presence of concomitant cognitive impairment has implications for

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13

Khrebtiy, G. I. "Chronic heart failure (pathogenetic aspects)." Thesis, БДМУ, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/17094.

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14

Wong, Chih Mun. "Heart failure in young adults." Thesis, University of Glasgow, 2015. http://theses.gla.ac.uk/7336/.

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Heart failure (HF) is a major health concern affecting 15 million people in Europe and around 900 000 people in the U.K. HF predominantly affects the elderly, with the mean age of patients with a diagnosis of HF between 70 and 80 years. Most previous HF studies have accordingly focused on older patients. Although HF is less common in younger adults (< 65 years), 15% to 20% of patients hospitalised with HF are younger than 60 years of age. Very few studies have described the characteristics of younger adults with HF and its outcome. The aims of this thesis are to describe the clinical character

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15

Damman, Kevin. "Cardiorenal interaction in heart failure." [S.l. : [Groningen : s.n.] ; University of Groningen] [Host], 2009. http://irs.ub.rug.nl/ppn/.

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16

Yao, Mu. "Study of mammalian heart failure." Thesis, The University of Sydney, 1997. https://hdl.handle.net/2123/27637.

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Heart failure is the end-stage of heart diseases. In this state the heart is unable to pump an adequate amount of blood to meet the metabolic requirement of the peripheral tissues. Heart failure is a complex clinical syndrome that can result from any heart disease. Clinically, it is manifested by cardiomegaly, breathlessness, and fluid retention. In spite of advances in pharmacological treatment, it remains a highly disabling and lethal disorder. Until now, the mechanism underlying this syndrome remains obscure. The major focus of this study was to investigate this mechanism by analysis of bo

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17

Shen, Li. "Sudden death and pump failure death in heart failure." Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/8651/.

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Sudden death and pump failure death are two major modes of death in patients with heart failure and reduced ejection fraction (HF-REF) and in patients with heart failure and preserved ejection fraction (HF-PEF). There have been advances in evidence-based treatments in patients with HF-REF over the last two decades, along with the changing patient characteristics in both HF-REF and HF-PEF populations. It is of great interest and significance to discover if these changes have translated into temporal changes (and corresponding trends over time) in the risks of sudden death and pump failure death

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18

Pratt, Rebekah Janet. "Broken hearts and the heart broken : living with, and dying from, heart failure in Scotland." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/8273.

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Heart failure is a common and serious chronic condition, which can be as ‘malignant’ as most forms of cancer (Stewart, MacIntyre, Hole, Capewell, & McMurray, 2001). Recent estimates are that around 40,000 men and 45,000 women are living with heart failure in Scotland (Stewart, MacIntyre, Capewell, & McMurray, 2003). Heart failure is significantly influenced by socioeconomic factors, with people on lower incomes being more likely to develop, and die faster from, heart failure (McAlister et al, 2004). There is a growing body of research on the experience of living with heart failure, however, no

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19

Lee, Wing-luen. "Multidisciplinary cardiac program for patients with heart failure." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43251328.

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20

Balmain, Bryce. "Thermoregulatory function during exercise in the heat in heart failure." Thesis, Griffith University, 2018. http://hdl.handle.net/10072/381512.

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This thesis examined thermoregulatory responses in heart failure (HF) patients during exercise at a fixed relative intensity, and at an intensity that elicited a fixed rate of metabolic heat production (Hprod) in a warm environment (30°C). Additionally, the efficacy of a chronic, high-dose (5mg/d for 6wk) pharmacological intervention (folic acid supplementation) as a strategy for improving skin blood flow (SkBF) responses and thus, thermoregulatory control in these patients during exercise was assessed. The findings of three experiments conducted to achieve these aims are presented in this the

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21

Von, Lanzenauer Stephan Haehling. "Studies of immune function in chronic heart failure, inflammation in the progression of chronic heart failure." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516814.

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22

Berry, Renee A. "Learning needs of heart failure patients." Muncie, Ind. : Ball S[t]ate University, 2009. http://cardinalscholar.bsu.edu/694.

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23

Al-Nasser, Faisal. "Beta-blockers in chronic heart failure." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406219.

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24

Davidoff, Allen Warren. "Congestive heart failure in the rat." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0022/MQ31340.pdf.

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25

Weernink, Corinne M. "Heart failure and respiratory muscle strength." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0001/MQ42222.pdf.

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26

Clark, Andrew Lawrence. "Exercise limitation in chronic heart failure." Thesis, Imperial College London, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389907.

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27

Doehner, Wolfram. "Metabolic studies in chronic heart failure." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417893.

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28

Gupta, Sanjay. "Studies of diuretics in heart failure." Thesis, University of Manchester, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538503.

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29

Oxberry, Stephen Grantley. "Opioids for breathlessness in heart failure." Thesis, University of York, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.550494.

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Breathlessness is a common and problematic symptom in heart failure. Opioids have traditionally been considered as analgesics, but a potential role for their use in breathlessness is beginning to emerge. This thesis commences with a review of the existing literature in support of a possible role for opioids in the management of breathless in heart failure. A systematic review of existing human symptom control studies in this thesis suggests that opioid administration may have a small but significant benefit in chronic heart failure. However, only six studies were included in the review and mos

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30

Laoutaris, Ioannis. "Respiratory muscle training in heart failure." Thesis, University of Birmingham, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.446347.

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31

Witte, Klaus Karl August. "Exercise intolerance in chronic heart failure." Thesis, King's College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429606.

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32

Beadle, Roger. "Metabolic manipulation in chronic heart failure." Thesis, University of Aberdeen, 2013. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=201651.

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Treatments aimed at modifying cardiac substrate utilisation are designed to improve metabolic efficiency. In the fasting state, the heart mainly relies on fatty acid oxidation for its energy production. The heart can adapt to metabolise glucose, lactate and amino acids depending on the predominate milieu and demands placed upon it. A shift from fatty acid oxidation to carbohydrate oxidation leads to a lower oxygen consumption per unit of adenosine triphosphate produced. It is this concept of improving cardiac efficiency by a reduction in oxygen demand that underpins the use of metabolic manipu

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33

Kiilavuori, Kai. "Physical training in chronic heart failure." Helsinki : University of Helsinki, 2000. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/kiilavuori/.

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34

Jensen, Gwenneth Anne. "Outcomes of heart failure discharge instructions." Diss., University of Iowa, 2011. https://ir.uiowa.edu/etd/3318.

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Acute decompensation of chronic heart failure is common and results in many patients being re-hospitalized every year (Jancin 2008). One of four voluntary core measures deployed by the Joint Commission for evaluation of quality of heart failure care in hospitals is heart failure discharge instructions, also called core measure HF1. Although the core measure is a widely disseminated standardized measure related to discharge education, there is little evidence about its impact on patient or readmission outcomes. The purpose of this study was to determine the relationship between the completion o

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35

Wingham, Jennifer. "Living with heart failure : self management, informed support and the role of the heart failure specialist nurse." Thesis, Exeter and Plymouth Peninsula Medical School, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.553683.

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People with heart failure frequently experience poor quality of life, often exacerbated by co-morbidities. This demands complex self-management activities, often supported by family members in care roles, and includes input from community Heart Failure Specialist Nurses (HFSNs) that is known to reduce hospital readmissions. There is, however, a paucity of knowledge about the perceptions of people living with heart failure concerning self-management strategies. Aim This thesis is a longitudinal study exploring emergent patterns and styles of self- management of persons with heart failure, the i

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36

Mbasu, Richard Juma. "Distinguishing heart failure with preserved ejection fraction from heart failure with reduced ejection fraction using proteomics techniques." Thesis, University of Leicester, 2016. http://hdl.handle.net/2381/39013.

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Heart failure is the second leading cause of morbidity and mortality in the world after cancer. In the UK, over 500,000 people are living with heart failure of which 30-40% die within 1 year of diagnosis. Some biomarkers for diagnosis and prognosis of heart failure have been established. However, they suffer from poor levels of accuracy and efficacy and their roles in clinical use is poorly understood. Thus, new biomarkers are needed. In this research, mass spectrometry based proteomics was used to profile patients plasma for clinical biomarker discovery due to its ability to perform both quan

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37

李詠鸞 and Wing-luen Lee. "Multidisciplinary cardiac program for patients with heart failure." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43251328.

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38

Andersson, Johanna. "The Heart Companion: : Designing an empowering application for heart failure patients." Thesis, KTH, Medieteknik och interaktionsdesign, MID, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-173382.

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Healthcare practices are changing as focus shifts fromtreating acute illnesses to chronic diseases. Theresponsibility of managing the treatment has shifted fromhealthcare providers to the individual in a higher degree. Toachieve good treatment the patients need to be empoweredso that they understand their condition and can makeinformed choices throughout their self-care. A researchthrough design approach was used to investigate how todesign a personalized empowering application for heartfailure patients. Aside from information relating to thecondition, the themes of physical activity, dieting

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39

Jones, David Gareth. "Interventional electrophysiology in advanced heart disease atrial fibrillation and heart failure." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/10946.

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The optimal therapy for atrial fibrillation (AF) associated with heart failure (HF) is unclear. Drug-based rhythm control has not proved clinically beneficial. Catheter ablation-based rhythm control improves cardiac function in HF patients, but impact on physiological performance has not been formally evaluated in a randomised trial. A randomised trial was designed and conducted, comparing catheter ablation with rate control in adults with symptomatic heart failure, radionuclide left ventricular ejection fraction (EF) ≤35%, and persistent AF. The primary outcome was change in peak oxygen consu

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40

Strömberg, Anna. "Caring for patients with chronic heart failure : with focus on patient education and nurse-led heart failure clinics /." Linköping : Univ, 2001. http://www.bibl.liu.se/liupubl/disp/disp2001/med708s.pdf.

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41

Batbold, Dulguun. "Addressing the Hidden Heart Failure in Mongolia; a Proposal of Heart Failure Patient Education and Disease Management Program." Digital Archive @ GSU, 2013. http://digitalarchive.gsu.edu/iph_theses/280.

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The prevalence of heart failure became a major and growing public health problem globally, with rising mortality numbers causing a great financial burden. In Mongolia, the hospitalization for cardiovascular diseases makes up 55% of all hospitalizations, and mortality rate of circulatory diseases was the highest nationwide, accounting for 36.7% of all deaths (S.Ariuntuya et al., 2011). However, there is still no formal research addressing the prevalence of heart failure in Mongolia. Therefore, this paper is meant to bring awareness of the problem of hidden heart failure in Mongolia, which might

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42

Bosco-Lévy, Pauline. "Heart failure in France : chronic heart failure therapeutic management and risk of cardiac decompensation in real-life setting." Thesis, Bordeaux, 2019. http://www.theses.fr/2019BORD0348.

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En France, environ un million de personnes seraient touchées par l’insuffisance cardiaque (IC) ; on recense près de 70 000 décès liés à l’IC, et plus de 150 000 hospitalisations et cela, malgré une prise en charge thérapeutique bien codifiée. Ces chiffres devraient s’accroitre dans les années futures du fait notamment du vieillissement de la population.L’objectif de ce travail était d’étudier l’utilisation des traitements pharmacologiques indiqués dans le traitement de l’IC (beta bloquant, inhibiteur de l’enzyme de conversion, anti-aldostérone, antagoniste des récepteurs à l’angiotensine II, d

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43

Gusdal, Annelie K. "Family caregiving for persons with heart failure : Perspectives of family caregivers, persons with heart failure and registered nurses." Doctoral thesis, Mälardalens högskola, Hälsa och välfärd, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-35194.

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Heart failure is a growing public health problem associated with significant morbidity and mortality. Family support positively affects outcomes for the person with heart failure while also leading to caregiver burden. Registered nurses have a key role in supporting and meeting the needs of family caregivers. The overall aim was to explore the situation and needs of family caregivers to a person with heart failure, and explore requisites and ways of supporting and involving family caregivers in heart failure nursing care. Two interview studies, one web survey study and one intervention study w

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44

Smart, Neil Andrew. "Mechanisms of response to exercise training in heart failure /." [St. Lucia, Qld.], 2005. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe19281.pdf.

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45

Sörensen, Jens. "PET in Heart Failure - Methods and Applications." Doctoral thesis, Uppsala University, Clinical Physiology, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4654.

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<p>Positron Emission Tomography (PET) permits regional myocardial perfusion, fibrosis and oxidative metabolism to be non-invasively quantified with radioactive tracers such as [<sup>15</sup>O]-water and [1-<sup>11</sup>C]-acetate. PET is an established research tool in congestive heart failure (CHF), a major cause of morbidity and mortality. However, as CHF is a syndrome that eventually affects all aspects of cardiac and systemic hemodynamic function, more clinically relevant information from a single PET scan is desirable. The aim of this thesis therefore was to develop and implement some new

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46

Davies, Lewis Ceri. "Cardiovascular control mechanisms in chronic heart failure." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.397946.

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47

Hsiao, Lien-Cheng. "Cardiac stem cell therapy for heart failure." Thesis, University of Oxford, 2012. https://ora.ox.ac.uk/objects/uuid:c4fcb449-2d05-4dc6-9a8d-f7450c0b200c.

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Cardiovascular disease is a leading cause of death worldwide and becomes increasingly prevalent in the elderly population. Independent of etiopathogenesis, heart failure (HF) is the final common stage of numerous heart diseases. Cardiac stem cell (CSC) therapy has emerged as a promising cell-based strategy for treatment of HF. However, cell replacement is not able to fully restore a structurally damaged myocardium in advanced and end-stage HF. The objective of this project was to test the following hypotheses: that a bioengineered heart extracellular matrix (ECM) with preserved intact geometri

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48

Smith, Lindsay Anne. "Sleep-disordered breathing and chronic heart failure." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/29371.

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Methods: Patients with stable symptomatic chronic heart failure were screened for sleep-disordered breathing by home sleep study. Daytime sleepiness was assessed by Epworth Sleepiness Scale and heart failure severity by symptom class, left ventricular ejection fraction and serum N-terminal pro-brain natriuretic peptide concentrations. In a subset of patients, synchronous in-laboratory limited sleep studies and polysomonography, and home limited sleep studies, were performed prospectively. Patients with obstructive sleep apnoea and stable symptomatic chronic heart failure were randomised to noc

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49

Murchie, Karen J. (Karen Jo) 1973. "Arterial function in hypertension and heart failure." Monash University, Faculty of Medicine, 2000. http://arrow.monash.edu.au/hdl/1959.1/8884.

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50

Ahlers, Belinda A. "Regulated L-Arginine transport in heart failure." Monash University, Faculty of Medicine, 2003. http://arrow.monash.edu.au/hdl/1959.1/9521.

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