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Academic literature on the topic 'Heart of a dog'

Author: Grafiati

Published: 4 June 2021

Last updated: 27 April 2022

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Journal articles on the topic "Heart of a dog"

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Shapiro, Alan. "Dog Heart." Hopkins Review 7, no. 4 (2014): 463–64. http://dx.doi.org/10.1353/thr.2014.0097.

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Rouslin, W., and C. W. Broge. "Mechanisms of ATP conservation during ischemia in slow and fast heart rate hearts." American Journal of Physiology-Cell Physiology 264, no. 1 (1993): C209—C216. http://dx.doi.org/10.1152/ajpcell.1993.264.1.c209.

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In the present study we compared the quantitatively most important, Pi-activated mechanisms for conserving ATP during ischemia in dog and rat cardiac muscle. Earlier studies by ourselves showed that dog heart, like all slow heart rate mammalian hearts examined, possesses the ability to inhibit its mitochondrial ATPase by binding IF1, the ATPase inhibitor protein, during ischemia. Rat heart, like other fast heart rate mammalian hearts studied, does not. The present study demonstrated that this IF1-mediated ATPase inhibition in ischemic dog heart, as in other slow heart rate hearts, appears to depend on matrix space acidification mediated largely by Pi-H+ symport via the mitochondrial Pi carrier. The present study further confirmed that maximal glycolytic flux rates are five- to sixfold greater in ischemic rat than in ischemic dog heart. Both of these systems are activated by increasing Pi concentration ([Pi]) during ischemia, and both appear to be regulated somewhat differently in dog than in rat heart. Thus intact dog heart mitochondria exhibited a [Pi]-dependent ATPase inhibition at low external pH, whereas rat heart mitochondria did not. The [Pi] required for maximal ATPase inhibition in dog heart mitochondria was approximately 6 mM. Although both dog and rat heart phosphofructokinase were stimulated by Pi, the enzyme in dog heart was maximally activated by approximately 6 mM Pi, whereas the rat heart enzyme required only approximately 3 mM Pi for its maximal stimulation under otherwise identical conditions. The most active nonmitochondrial ATPase in ischemic dog and rat cardiac muscle, the Ca(2+)-activated actomyosin ATPase, accounted for approximately one-half of the total nonmitochondrial ATPase activity in each species.(ABSTRACT TRUNCATED AT 250 WORDS)

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Anninskii, Lev. "Heart of a Dog?" Soviet Studies in Literature 27, no. 4 (1991): 44–61. http://dx.doi.org/10.2753/rsl1061-1975270444.

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Toerien, Barend J., and Breyten Breytenbach. "Dog Heart (A Travel Memoir)." World Literature Today 73, no. 3 (1999): 583. http://dx.doi.org/10.2307/40155021.

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Balcells, Eduardo, Qing C. Meng, Walter H. Johnson, Suzanne Oparil, and Louis J. Dell’Italia. "Angiotensin II formation from ACE and chymase in human and animal hearts: methods and species considerations." American Journal of Physiology-Heart and Circulatory Physiology 273, no. 4 (1997): H1769—H1774. http://dx.doi.org/10.1152/ajpheart.1997.273.4.h1769.

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The current study examined the contributions of angiotensin-converting enzyme (ACE) vs. chymase to angiotensin II (ANG II) generation in membrane preparations from left ventricles of humans, dogs, rabbits, and rats and from total heart of mice. ACE and chymase activity were measured in membrane preparations extracted with low or high detergent (LD and HD, respectively) concentrations. We hypothesized that ACE, which is membrane bound in vivo, would be preferentially localized to the HD preparation, whereas chymase, which is localized to the cytoplasm and cardiac interstitium, would be localized to the LD preparation. In human heart, ACE activity was 16-fold higher in the HD than in the LD preparation, whereas chymase activity was 15-fold higher in the LD than in the HD preparation. Total ANG II formation was greater in human heart [15.8 ± 3.4 (SE) μmol ANG II ⋅ g−1 ⋅ min−1] than in dog, rat, rabbit, and mouse hearts (3.90 ± 0.35, 0.41 ± 0.02, 0.61 ± 0.07, and 1.16 ± 0.08 μmol ANG II ⋅ g−1 ⋅ min−1, respectively, P < 0.05, by analysis of variance). ANG II formation from ACE was higher in mouse heart (1.09 ± 0.05 μmol ANG II ⋅ g−1 ⋅ min−1, P < 0.001) than in rabbit, human, dog, and rat hearts (0.55 ± 0.06, 0.34 ± 0.01, 0.32 ± 0.06, and 0.31 ± 0.02 μmol ANG II ⋅ g−1 ⋅ min−1, respectively). In contrast, chymase activity was higher in human heart (15.3 ± 3.4 μmol ANG II ⋅ g−1 ⋅ min−1) than in dog, rat, rabbit, and mouse hearts (3.59 ± 0.29, 0.10 ± 0.01, 0.06 ± 0.01, and 0.07 ± 0.01 μmol ANG II ⋅ g−1 ⋅ min−1, respectively). Our results demonstrate important species differences in the pathways of intracardiac ANG II generation. Chymase predominated over ACE activity in human heart, accounting for extremely high total ANG II formation in human heart compared with dog, rat, rabbit, and mouse hearts.

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Griffiths, E. J., and A. P. Halestrap. "Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion." Biochemical Journal 307, no. 1 (1995): 93–98. http://dx.doi.org/10.1042/bj3070093.

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1. The yield of mitochondria isolated from perfused hearts subjected to 30 min ischaemia followed by 15 min reperfusion was significantly less than that for control hearts, and this was associated with a decrease in the rates of ADP-stimulated respiration. 2. The presence of 0.2 microM cyclosporin A (CsA) in the perfusion medium during ischaemia and reperfusion caused mitochondrial recovery to return to control values, but did not reverse the inhibition of respiration. 3. A technique has been devised to investigate whether the Ca(2+)-induced non-specific pore of the mitochondrial inner membrane opens during ischaemia and/or reperfusion of the isolated rat heart. The protocol involved loading the heart with 2-deoxy[3H]glucose ([3H]DOG), which will only enter mitochondria when the pore opens. Subsequent isolation of mitochondria demonstrated that [3H]DOG did not enter mitochondria during global isothermic ischaemia, but did enter during the reperfusion period. 4. The amount of [3H]DOG that entered mitochondria increased with the time of ischaemia, and reached a maximal value after 30-40 min of ischaemia. 5. CsA at 0.2 microM did not prevent [3H]DOG becoming associated with the mitochondria, but rather increased it; this was despite CsA having a protective effect on heart function similar to that shown previously [Griffiths and Halestrap (1993) J. Mol. Cell. Cardiol. 25, 1461-1469]. 6. The non-immunosuppressive CsA analogue [MeAla6]cyclosporin was shown to have a similar Ki to CsA on purified mitochondrial peptidyl-prolyl cis-trans-isomerase and mitochondrial pore opening, and also to have a similar protective effect against reperfusion injury. 7. Using isolated heart mitochondria, it was demonstrated that pore opening could become CsA-insensitive under conditions of adenine nucleotide depletion and high matrix [Ca2+] such as may occur during the initial phase of reperfusion. The apparent increase in mitochondrial [3H]DOG in the CsA-perfused hearts is explained by the ability of the drug to stabilize pore closure and so decrease the loss of [3H]DOG from the mitochondria during their preparation.

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Van Winkle, D. M., A. N. Swafford, and J. M. Downey. "Subendocardial coronary compression in beating dog hearts is independent of pressure in the ventricular lumen." American Journal of Physiology-Heart and Circulatory Physiology 261, no. 2 (1991): H500—H505. http://dx.doi.org/10.1152/ajpheart.1991.261.2.h500.

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Ventricular decompression has been shown to have little effect on either the magnitude or transmural distribution of the extravascular resistance in the small hearts of the cat or rabbit. This study tests whether that independence from ventricular pressure also occurs in the large heart of the dog, which should be more representative of the human. We measured regional myocardial flow in each in situ dog heart during three conditions: normally beating, vented beating, and arrest. Hearts were perfused at constant pressure and maximally dilated with 0.4-1.0 mg/min ic adenosine. Total coronary blood flow was measured with an electromagnetic flowmeter, and regional flow was assessed with radiolabeled microspheres. Although arrest resulted in more than a doubling of flow to the inner layer, greatly reducing ventricular pressure by venting had no significant effect on subendocardial flow. Subepicardial flow was minimally affected by either venting or arrest. We conclude that both the magnitude and the transmural distribution of extravascular resistance in the large heart of the dog is unrelated to the pressure in the ventricular lumen.

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Rouslin, W., C. W. Broge, and I. L. Grupp. "ATP depletion and mitochondrial functional loss during ischemia in slow and fast heart-rate hearts." American Journal of Physiology-Heart and Circulatory Physiology 259, no. 6 (1990): H1759—H1766. http://dx.doi.org/10.1152/ajpheart.1990.259.6.h1759.

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In the present study, isolated dog and rat hearts were perfused in the Langendorff mode with Krebs bicarbonate buffer in the absence and presence of 10(-5) M oligomycin. The perfusion protocols employed allowed tissue pH to drop during subsequent ischemic incubations essentially as it would in blood-perfused hearts. Tissue pH, ATP, lactate, and mitochondrial respiratory function were measured during the course of subsequent zero-flow ischemic incubations. The adenosinetriphosphatase (ATPase) activities attributable to both mitochondrial and nonmitochondrial ATPases in sonicated heart homogenates and the actomyosin ATPase in isolated cardiac myofibrils were measured in both species. Consistent with earlier results with a different model in which tissue pH was buffered during the ischemic incubations [W. Rouslin, J. L. Erickson, and R. J. Solaro. Am. J. Physiol. 250 (Heart Circ. Physiol. 19): H503-H508, 1986], the inhibition of the mitochondrial ATPase in situ by oligomycin markedly slowed both tissue ATP depletion and the loss of mitochondrial function during ischemia in the dog. However, oligomycin had only a very small and transient effect on ATP depletion and mitochondrial function in the rat. This was apparently so because of the fivefold higher rate of glycolytic ATP production as well as the nearly threefold higher total nonmitochondrial ATPase activity of ischemic rat compared with ischemic dog heart. These results suggest that although the inhibition of the mitochondrial ATPase makes a major contribution to ATP conservation in ischemic dog heart, it makes only a very small contribution in rat.

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Patterson, D. F. "CONGENITAL HEART DISEASE IN THE DOG*." Annals of the New York Academy of Sciences 127, no. 1 (2006): 541–69. http://dx.doi.org/10.1111/j.1749-6632.1965.tb49423.x.

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MATIC, S. E. "Congenital heart disease in the dog." Journal of Small Animal Practice 29, no. 12 (1988): 743–59. http://dx.doi.org/10.1111/j.1748-5827.1988.tb01900.x.

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Dissertations / Theses on the topic "Heart of a dog"

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Clapham, John Christopher. "Characterisation and structural studies on dog heart cyclic nucleotide phosphodiesterase." Thesis, Birkbeck (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267913.

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Sidhu, Ravinder. "Expression and characterisation of a novel cyclic nucleotide phosphodiesterase type 1A from dog heart." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398216.

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Grėbliauskas, Lukas. "Dažniausiai pasitaikantys šunų širdies ritmo sutrikimai, jų diagnostika ir gydymas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140305_142422-03298.

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Pagrindinis darbo tikslas buvo išsiaiškinti, kokie yra dažniausiai pasitaikantys šunų širdies ritmo sutrikimai, kokie pagrindiniai diagnostiniai metodai naudojami aritmijoms nustatyti ir diferencijuoti, bei aprašyti medikamentinius preparatus, naudojamus gydant šunis nuo aritmijų. Darbo metu buvo analizuojami LSMU VA Dr. L. Kiaučeliūno smulkiųjų gyvūnų klinikoje, nuo 2008 iki 2013 metų, surinkti gydytų šunų duomenys, kuriems pasireiškė širdies ritmo sutrikimai. Buvo analizuojami pacientų anamnezės duomenys, kuriuos pateikė gyvūnų savininkai, ieškoma aritmijų pasireiškimo priklausomybių nuo šunų lyties, veislės, amžiaus, kilmės, svorio. Širdies ritmo sutrikimai buvo nustatyti 145 šunims, iš kurių 103 buvo patinai ir 42 patelės. Širdies ritmo sutrikimai buvo diagnozuojami auskultuojant širdies darbą, atliekant echokardiografiją, rentgeninį tyrimą bei užrašant elektrokardiogramą – tai yra pagrindinis aritmijų tyrimo metodas. Buvo nustatyta, jog dažniausiai pasitaikantis širdies ritmo sutrikimas šunims yra sinusinės aritmijos, kurios pasireiškė 61 pacientui, tai sudarė 42 proc. šunų, kuriems buvo nustatytos aritmijos. Be sinusinių aritmijų, tiriamojoje šunų grupėje, buvo nustatyti dar 6 rūšių širdies ritmo sutrikimai: supraventrikulinės ekstrasistolijos buvo diagnozuotos 21 (14,5 proc.) šuniui, ventrikulinės ekstrasistolijos – 34 (23,4 proc.), Hiso pluošto kojyčių blokados – 9 (6,2 proc.), Io AV blokados – 10 (6,9 proc.), IIo AV blokados – 6 (4,1 proc.), o IIIo AV blokados - 3 (2... [toliau žr. visą tekstą]<br>The main aim of work – to determine what are the most common canine cardiac rhythm disorders, analyse diagnostic methods and describe basic medical drugs used in the treatment of arrhythmias. Data of dogs morbidity of cardiac rhythm disorders in 2008 – 2013 has been collected at Dr. L. Kriaučeliūnas Small Animal Clinic of Veterinary Academy of Lithuanian University of Health Sciences. Cardiac rhythm disorders have been diagnosed to 145 dogs: 103 of them were males, and 42 – were females. Clinical diagnosis has been approved according to results of diagnostic methods like: auscultation of heart rate and sounds, X-ray, cardioechoscopy and the main diagnostic method of cardiac arrhythmias – EKG. Sinus arrhythmia has been determined as the most common cardiac rhythm disorder of dogs. This type of arrhythmia has been diagnosed to 61 (42 %) dogs. There were more types of arrhytmias diagnosed like: premature ventricular contractions – 34 (23,4 %) cases, premature atrial contractions - 21 (14,5 %) cases, Hiss bundle branch blocks – 9 (6,2 %) cases and AV blocks – 17 (13,1 %) cases (p<0.001). Male dogs were ill with the cardiac rhythm disorders more often compared to females (71,0% vs. 29,0 %). Arrhythmias were diagnosed to 109 (75,2 %) purebred dogs and 36 (24,8 %) mixed breed dogs (p<0.01). Cardiac rhythm disorders have been diagnosed to 13 Rottweilers (11,9%) and 11 German Shepherds (10,0%), which were most common breeds (p<0.01). In addition, dogs from eight years old and older... [to full text]

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D'Ingeo, Serenella. "Laterality, heart rate and EEG as measurements of animal welfare in dogs and horses." Thesis, Rennes 1, 2019. http://www.theses.fr/2019REN1B010/document.

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Le bien-être animal est considéré un phénomène multidimensionnel basé sur les conditions et les expériences de vie de chaque individu, et lié aux fonctions organiques et à la sensibilité de l’individu même. L’étude des émotions animales est complexe mais les hypothèses sur leurs états émotifs peuvent être formulées sur la base de mesures neurophysiologiques, comportementales et cognitives. Des études récentes ont montré que la latéralité cérébrale et comportementale, la fréquence cardiaque et l'activité cérébrale (mesurée par électroencéphalographie sont des paramètres qui permettent d’évaluer la perception de la valence et du niveau stimulant des émotions chez l’animal et l'Homme. Le but principal de ce projet de thèse était d’étudier la perception que les chiens et les chevaux ont du contenu émotionnel des signaux humains et l’impact potentiel que peuvent avoir ces signaux sur l’état émotionnel de ces animaux et par conséquent sur leur bien-être. Dans ce but, nous avons présenté à ces animaux des stimuli exprimant diverses émotions. Nous avons utilisé une approche intégrée combinant l’analyse de la latéralité comportementale, de la fréquence cardiaque, de l’activité cérébrale et du comportement des sujets afin de répondre à 2 questions: 1) les chiens et les chevaux perçoivent-ils le contenu émotionnel des signaux humains? 2) Les chiens et les chevaux attribuent-ils une valence et une intensité différentes selon les émotions humaines perçues. Les résultats de ce travail de thèse montrent que les chiens et les chevaux traitent différemment les signaux émotionnels en fonction de leur valence et de leur intensité. La perception de la voix de l'homme par le cheval est modulée par la valence des interactions homme-cheval antérieures et par les conditions de vie des chevaux. En ce qui concerne les chiens, nos résultats montrent qu’ils discriminent et perçoivent les émotions contenues dans les signaux visuels, auditifs et olfactifs humains différemment, et nous fournissent de nouvelles connaissances sur le fonctionnement émotionnel du cerveau du chien. Les résultats de ce travail de thèse apportent un cadre théorique pour définir des paramètres utiles à l'évaluation du bien-être animal<br>Animal welfare is considered to be a multidimensional phenomenon based upon life experiences and conditions, characterized by how an individual feels and functions. The study of emotions in animals is difficult but assumptions of emotional states are usually derived from neurophysiological, behavioral and cognitive measurements. Recent literature shows that cerebral and behavioral laterality, cardiac activity and brain activity (measured by electroencephalography) are suitable parameters to examine animals’ and human emotional processing along the valence and arousal dimensions. The main aim of the present research project was to investigate dogs and horses perception of the emotional content of human signals that potentially affects animals’ affective state and welfare. An integrated approach combining the analysis of behavioral lateralization, cardiac and brain activity, and subjects’ behavior was applied in order to answer to the following questions: 1) Do dogs and horses perceive the different emotional content of human signals? 2) Do dogs and horses attribute a different valence and intensity to the human emotions perceived? Overall, the results of this thesis project demonstrate that dogs and horses process differently emotional signals according to their valence and intensity. In particular, horses perception of a human voice is modulated by the valence of the prior horse-human interactions and by subjects’ living conditions. As for dogs, results demonstrate that they discriminate and perceive differently the emotional content of human visual, auditory and olfactory signals, providing new insights into the emotional functioning of the canine brain. The current research offers a theoretical framework for defining useful parameters to evaluate animal welfare

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Hall, Laura E. "A practical framework for harmonising welfare and quality of data output in the laboratory-housed dog." Thesis, University of Stirling, 2014. http://hdl.handle.net/1893/21156.

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In the UK, laboratory-housed dogs are primarily used as a non-rodent species in the safety testing of new medicines and other chemical entities. The use of animals in research is governed by the Animals (Scientific Procedures) Act (1986, amended 2012) and legislation is underpinned by the principles of humane experimental technique: Replacement, Reduction and Refinement. A link between animal welfare and the quality of data produced has been shown in other species (e.g. rodents, nonhuman primates), however, no established, integrated methodology for identifying or monitoring welfare and quality of data output previously existed in the laboratory-housed dog. In order to investigate the effects of planned Refinements to various aspects of husbandry and regulated procedures, this project sought to integrate behavioural, physiological and other measures (e.g. cognitive bias, mechanical pressure threshold) and to provide a means for staff to monitor welfare whilst also establishing the relationship between welfare and quality of data output. Affective state was identified using an established method of cognitive bias testing, before measuring welfare at ‘baseline’ using measures of behaviour and physiology. Dogs then underwent ‘positive’ and ‘negative’ behavioural challenges to identify the measures most sensitive to changing welfare and most suitable for use in a framework. The resulting Welfare Assessment Framework, developed in three groups of dogs from contrasting backgrounds within the facility, found a consistent pattern of behaviour, cardiovascular function, affect and mechanical pressure threshold (MPT). Dogs with a negative affective state had higher blood pressure at baseline than those with positive affective states, and the magnitude of the effect of negative welfare suggests that welfare may act as a confound in the interpretation of cardiovascular data. The responses to restraint included increases in blood pressure and heart rate measures which approached ceiling levels, potentially reducing the sensitivity of measurement. If maintained over time this response could potentially have a negative health impact on other organ systems and affecting the data obtained from those. Dogs with a negative welfare state also had a lower mechanical pressure threshold, meaning they potentially experienced greater stimulation from unpleasant physical stimuli. Taken together with the behaviours associated with a negative welfare state (predominantly vigilant or stereotypic behaviours) the data suggest that dogs with a negative welfare state have a greater behavioural and physiological response to stimuli in their environment; as such, data obtained from their use is different from that obtained from dogs with a positive welfare state. This was confirmed by examining the effect size (Cohen’s d ) resulting from the analysis of affective state on cardiovascular data. An increase in variance, particularly in the small dog numbers typical of safety assessment studies, means a reduction in the power of the study to detect the effect under observation; a decrease in variation has the potential to reduce the number of dogs use, in line with the principle of Reduction and good scientific practice. The development of the framework also identified areas of the laboratory environment suitable for Refinement (e.g. restriction to single-housing and restraint) and other easily-implemented Refinements (e.g. feeding toy and human interaction) which could be used to improve welfare. As a result of this, a Welfare Monitoring Tool (WMT) in the form of a tick sheet was developed for technical and scientific staff to identify those dogs at risk of reduced welfare and producing poor quality data, as well as to monitor the effects of Refinements to protocols. Oral gavage is a common regulated procedure, known to be potentially aversive and was identified as an area in need of Refinement. A program of desensitisation and positive reinforcement training was implemented in a study also comparing the effects of a sham dose condition versus a control, no-training, condition. A number of the measures used, including home pen behaviour, behaviour during dosing, MPT and the WMT showed significant benefits to the dogs in the Refined condition. Conversely, dogs in the sham dose condition showed more signs of distress and took longer to dose than dogs in the control condition. The welfare of control dogs was intermediate to sham dose and Refined protocol dogs. This project identified a positive relationship between positive welfare and higher quality of data output. It developed and validated a practical and feasible means of measuring welfare in the laboratory environment in the Welfare Assessment Framework, identified areas in need of Refinement and developed practical ways to implement such Refinements to husbandry and regulated procedures. As such it should have wide implications for the pharmaceutical industry and other users of dogs in scientific research.

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da, Cunha Daise Nunes Queiroz. "Properties of flow through the ascending aorta in boxer dogs with mild aortic stenosis momentum, energy, Reynolds number, Womersley's, unsteadiness parameter, vortex shedding, and transfer function of oscillations from aorta to thoracic wall /." Columbus, Ohio : Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1243910694.

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Champion, Tatiana [UNESP]. "Avaliação da função cardíaca em cães com anemia normovolência aguda experimental." Universidade Estadual Paulista (UNESP), 2008. http://hdl.handle.net/11449/89207.

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Made available in DSpace on 2014-06-11T19:23:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-02-12Bitstream added on 2014-06-13T20:30:44Z : No. of bitstreams: 1 champion_t_me_jabo.pdf: 323780 bytes, checksum: 4f868294469f7f64bb21654ab1f98b7f (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>A anemia, condição clínica comum, está relacionada com disfunção cardiovascular, risco de insuficiência cardíaca congestiva, infarto do miocárdio e conseqüente aumento da mortalidade em seres humanos. São descritas alterações hemodinâmicas devido à ativação dos mecanismos compensatórios durante a anemia, na tentativa de minimizar ou evitar danos causados pela diminuição do aporte tecidual de oxigênio. Para o estudo de modelos experimentais de anemia em cães, têm-se utilizado a hemodiluição normovolêmica aguda. Assim, com este trabalho, objetivou-se analisar a possível influência da anemia sobre a função cardiovascular de cães. Para tanto, utilizaram-se dez cães adultos jovens, sem raça definida, com anemia normovolêmica aguda induzida experimentalmente. Este procedimento consistiu na retirada de 20% do volume sangüíneo circulante e reposição da volemia com solução colóide e cristalóide, até atingir hematócrito igual ou abaixo de 18%. Após a indução da anemia, avaliaram-se parâmetros cardiovasculares, como a troponina sérica, eletrocardiográficos, de pressão arterial e ecodopplercardiográficos. Também foram calculadas algumas variávies hemodinâmicas e hemogasométricas. Os cães anêmicos apresentaram diminuição da pressão arterial sistêmica, alteração do ritmo eletrocardiográfico de arritmia sinusal para ritmo sinusal, alterações ecocardiográficas indicando hiperfunção sistólica, porém sem indícios de disfunção diastólica, ausência de lesões na ultra-estrutura miocárdica, confirmada pelos níveis de troponina I, ausência de distúrbios acidobásicos e alterações hemodinâmicas significativas como aumento do índice cardíaco, do volume sistólico e diminuição do índice de resistência vascular periférica.<br>In humans, anemia is related to cardiovascular dysfunction, risk of congestive heart failure, and myocardial infarction, with subsequent increases in mortality. In the anemic state, activation of compensatory mechanisms results in hemodynamic changes. These changes minimize or avoid damages caused by reduced delivery of oxygen to body tissues. Studies of the effects of acute normovolemic anemia have often used the dog as a model. Thus, to better understand the canine response to anemia, further evaluation of the cardiovascular function of anemic dogs is necessary. This research aimed at evaluating the potential influence of anemia on dogs cardiovascular function. For such, acute normovolemic anemia was induced in ten adult mongrel dogs. To induce anemia, approximately 20% of the circulating blood volume was removed and replaced with equal volumes of a colloid and crystalloid solution. Under these conditions, the hematocrit was reduced to less than 18%. The serum troponin, blood pressure, electrocardiogram, and echodopplercardiogram evaluations were performed after the induction of anemia. There also were evaluated acid base and hemodynamic variables. The anemic dogs presented reduction of the arterial blood pressure and change of the cardiac rhythm from sinusal arrhythmia to sinusal rhythm, on the echocardiography, the dogs showed systolic hyperfunction, however without diastolic dysfunction, absence of myocardic ultra structure injury, confirmed by troponin I levels, absence of acid-base disturbs and significant hemodynamic modifications, like increases of cardiac indices, systolic volume and decrease of peripheral vascular resistance indices.

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Roux, Christine Ann. "South African memoirs in a decade of transition: Athol Fugard's Cousins (1994), J.M. Coetzee's Boyhood (1997), and Breyten Breytenbach's Dog Heart (1999)." Thesis, Rhodes University, 2002. http://hdl.handle.net/10962/d1002233.

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This thesis examines three South African memoirs using M. M. Bakhtin’s theories of the dialogical relationship in language and literature. By offering an alternative to a postmodern or multicultural interpretation of autobiographies, Bakhtin’s precepts, that define a dialogic, help to reframe a way of discussing memoirs and avoiding dead-ends previously arrived at by essayists in James Olney’s 1980 collection. Bakhtin’s ideas discussed here, which include the “once-occurrent moment”, “architectonic contraposition”, ”emotional-volitional tone”, “alibi”, “non-alibi”, and “centripetal” and “centrifugal” force, help to rebuild a discussion based on temporary and evolving self truth rather than fiction, the postmodern interpretation, or confession, the new-age secular spiritualism based on multicultural and politically correct standards. For this, each author’s memoir had to be examined separately and a conclusion was arrived at through inductive analysis. Rather than try to find similar characteristics, I focused on what made each memoir different and unique. Janet Varner Gunn’s Autobiography: Toward A Poetics of Experience (1982) refocused the debate over autobiography on process. The question, what steps did each author take toward writing about himself, led the discussion to an examination of the priorities each author exemplified. Beginning with Fugard who emphasized spatial, concrete, and sensory detail to help him contain his emotional life, the thesis moves on to an examination of Coetzee’s sense of justice. From the physical and intellectual world follows Breytenbach’s spiritual space-making. In each memoir, control of space is evident on different levels of experience. Articulating space inevitably leads to a discussion of boundaries. Here, Charles Taylor’s emphasis on the modern self’s need to articulate a horizon or a framework is helpful in generalizing the effect of the autobiographical process. The conclusion reached is that autobiography is inherently centrifugal: it moves away from the center of cultural thinking because its “truth” bolsters itself on dialogical process which does not depend on a fixed authority but rather on communicative exchange. As an example of exchange, autobiography’s central truth is that it returns to a “unique point of origin”, namely the self, only to reconnect to the other in a potentially eternal exchange of responsiveness moving away from the center.

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Hansson, Kerstin. "Diagnostic imaging of cardiopulmonary structures in normal dogs and dogs with mitral regurgitation /." Uppsala : Dept. of Biomedicine and Veterinary Public Health, Division of Diagnostic Imaging and Clinical Pathology, Swedish Univ. of Agricultural Sciences, 2004. http://epsilon.slu.se/v167.pdf.

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Zamora, Restan Wilmer Alejandro [UNESP]. "Determining lactate and glucose thresholds and heart rate deflection point in dogs undergoing incremental exercise testing." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/149857.

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Submitted by WILMER ALEJANDRO ZAMORA RESTAN null (alejomvz1208@gmail.com) on 2017-03-21T13:20:32Z No. of bitstreams: 1 Dissertação Final[924].pdf: 1300036 bytes, checksum: a71c43e8746de0b8643dcf3f0300ac03 (MD5)<br>Approved for entry into archive by Luiz Galeffi (luizgaleffi@gmail.com) on 2017-03-22T14:28:53Z (GMT) No. of bitstreams: 1 zamorarestan_wa_me_jabo.pdf: 1300036 bytes, checksum: a71c43e8746de0b8643dcf3f0300ac03 (MD5)<br>Made available in DSpace on 2017-03-22T14:28:53Z (GMT). No. of bitstreams: 1 zamorarestan_wa_me_jabo.pdf: 1300036 bytes, checksum: a71c43e8746de0b8643dcf3f0300ac03 (MD5) Previous issue date: 2017-02-22<br>O propósito deste estudo foi comparar métodos para determinação dos limiares relacionados com curvas de lactato plasmático e suas intensidades. Determinaram-se os limiares (1) de lactato (LTv) e (2) glicêmico (GTv) visualmente, (3) o limiar de lactato por meio do modelo polinomial (LTp), (4) limiar de glicose pelo modelo polinomial (GTp) e (5) o ponto de deflexão da frequência cardíaca (FCdp). Dezoito Beagles foram submetidos a teste de esforço incremental (IET). O IET foi realizado numa esteira, sendo concluído quando os cães mostraram sinais de fadiga. Os LTv GTv e FCdp foram determinados visualmente; LTp e GTp foram obtidos matematicamente por meio de função polinomial. Análise de variância (ANOVA), correlação de Pearson, regressão ordinária dos produtos mínimos e Bland-Altman foram utilizadas para avaliar a concordância entre as variáveis. Não houve diferença entre as velocidades relacionadas aos limiares (P >0.05). Houve correlação entre LTv e GTv (r = 0,91), LTv e LTp (r = 0,96), LT e GTp (r = 0,94) e a velocidade de corrida no ponto de deflexão da freqüência cardíaca (Vdp) e LT (r = 0,95 ) (P < 0,05). Foi observado viés constante entre LTv e LTp. Foi possível a determinação dos limiares de lactato e glicêmico em cães, sendo que a concordância entre LTv e FCdp indicou que a FC pode ser utilizada como método indireto para a obtenção do limiar de lactato.<br>The aim of this study was to compare methods to determining visually (1) lactate threshold (LTv), (2) glycemic threshold (GTv) and (3) lactate threshold by the polynomial model (LTp), (4) glucose threshold by the polynomial model (GTp), and (5) heart rate deflection point (HRdp). Eighteen Beagles underwent an incremental exercise testing (IET). IET was performed on the treadmill. The IET was completed when the dogs showed signs of fatigue. The LTv, GTv and HRdp were determined visually; LTp and GTp were obtained from the polynomial function. One-way analysis of variance, Pearson correlation, ordinary least product regressions and Bland-Altman plot were used to assess the agreement between the variables. There was no difference between the velocities corresponding to the thresholds (P >0,05). There was a correlation between LTv and GTv (r = 0.91), LTv and LTp (r = 0.96), LT and GTp (r = 0.94) and the running speed at the heart rate deflection point (Vdp) and LT (r = 0.95) (p <0.05). A constant bias was observed between LTv and LTp. It was possible to determine the lactate and glycemic thresholds in dogs, and the agreement between LTv and FCdp indicated that the HR can be used as an indirect method to obtain the lactate threshold.

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Books on the topic "Heart of a dog"

1

Dog-heart. Peepal Tree, 2010.

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Bulgakov, Mikhail Afanasʹevich. Heart of a dog. Grove Press, 1987.

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Bulgakov, Mikhail Afanasʹevich. Heart of a dog. Grove Weidenfeld, 1987.

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Galati, Frank. Heart of a dog. Dramatists Play Service, 1988.

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Breyten, Breytenbach. Dog heart: A memoir. Harcourt Brace, 1999.

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Galati, Frank. Heart of a dog. Dramatists Play Service, 1988.

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Breyten, Breytenbach. Dog heart: A memoir. Faber and Faber, 1999.

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Bulgakov, Mikhail Afanasʹevich. The heart of a dog. Pan, 1990.

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Galati, Frank. The heart of a dog. Theatre Communications Group, 1985.

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Carr, Claire. Of heritage & heart. Wynship Arts, 1994.

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Book chapters on the topic "Heart of a dog"

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Coleman, Amanda E., and Scott A. Brown. "Hypertension and the Heart and Vasculature." In Hypertension in the Dog and Cat. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-33020-0_8.

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Onoyama, Kaoru. "Volume and cardiac factors in the genesis of mineralocorticoid hypertension in the conscious dog." In The Heart in Hypertension. Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-0941-0_15.

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Gagelmann, M., K. Forssmann, A. Whalley, G. A. J. Riegger, and W. G. Forssmann. "Receptor binding of cardiac hormones to dog kidney with congestive heart failure." In Functional Morphology of the Endocrine Heart. Steinkopff, 1989. http://dx.doi.org/10.1007/978-3-642-72432-9_24.

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Barnes, K. L., D. B. Averill, J. P. Conomy, and C. M. Ferrario. "Rostral Solitary Tract Lesions Produce Vasopressin Dependent Hypertension in the Dog." In Central Nervous System Control of the Heart. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2327-3_3.

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Duwel, C. M. B., F. C. Visser, M. J. van Eenige, and J. P. Roos. "Variables of myocardial backdiffusion, determined with 17-IODO-131 heptadecanoic acid in the normal dog heart." In Lipid Metabolism in Normoxic and Ischemic Heart. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-1611-4_28.

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Davis, Christopher. "The Writing of Breyten Breytenbach, The Writing of Breyten Breytenbach: Dog Heart." In Postcolonial Traumas. Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1057/9781137526434_10.

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Westera, G., F. C. Visser, and E. E. van der Wall. "Uptake and distribution of radioiodinated free fatty acids in the dog heart." In Developments in Cardiovascular Medicine. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3287-6_4.

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Mitsumaru, Atsuhiro, Ryohei Yozu, Shinichi Taguchi, et al. "The Combined Use of Extra-Aortic Balloon Counterpulsation and a Ventricular Assist Cup for Acute Heart Failure in Dogs — Effects on Regional Blood Flow." In Heart Replacement. Springer Japan, 1998. http://dx.doi.org/10.1007/978-4-431-65921-1_67.

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Harrison, D. K., H. Günther, H. Vogel, et al. "Oxygen Supply and Microcirculation of the Beating Dog Heart after Haemodilution with Fluosol DA20%." In Advances in Experimental Medicine and Biology. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-3291-6_45.

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Burgin, Diana L. "Bulgakov’s Early Tragedy of the Scientist-Creator: An Interpretation of The Heart of a Dog." In From Symbolism to Socialist Realism, edited by Irene Masing-Delic. Academic Studies Press, 2019. http://dx.doi.org/10.1515/9781618111449-024.

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Conference papers on the topic "Heart of a dog"

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Jia, Congxian, Theodore J. Kolias, Jonathan M. Rubin, et al. "3D elasticity imaging on an open-chest dog heart." In 2009 IEEE International Ultrasonics Symposium. IEEE, 2009. http://dx.doi.org/10.1109/ultsym.2009.5441850.

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Luft, Maria Luise. "Creating Humans – Ethics of Scientific Progress: Frankenstein and Heart of a Dog." In International Conference «Responsible Research and Innovation. Cognitive-crcs, 2017. http://dx.doi.org/10.15405/epsbs.2017.07.02.73.

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Savelyeva, Tatayana. "Irony In The Novel "The Heart Of A Dog" By M. Bulgakov." In International Scientific Conference «Social and Cultural Transformations in the Context of Modern Globalism» dedicated to the 80th anniversary of Turkayev Hassan Vakhitovich. European Publisher, 2020. http://dx.doi.org/10.15405/epsbs.2020.10.05.444.

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Jia, Congxian, Ping Yan, Albert J. Sinusas, et al. "3D Elasticity imaging using principal stretches on an open-chest dog heart." In 2010 IEEE Ultrasonics Symposium (IUS). IEEE, 2010. http://dx.doi.org/10.1109/ultsym.2010.5935864.

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Sinigaglia, G., M. Nichelatti, P. Pettazzoni, F. Bersani, G. Goganyi, and G. Pallotti. "A dog and fox oscillator simulation for the coupling between heart and lungs." In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1988. http://dx.doi.org/10.1109/iembs.1988.94937.

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Lortie, Mireille, Jean DaSilva, Miran Kenk, Stephanie Thorn, Rob Beanlands, and Robert deKemp. "Kinetics of (R)-[11C] rolipram and (S)-[11C] rolipram In the Dog Heart: Investigation of Four Compartment Models." In 2006 IEEE Nuclear Science Symposium Conference Record. IEEE, 2006. http://dx.doi.org/10.1109/nssmic.2006.356431.

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Krug, Alfons, Manfred D. Kessler, Raja Khuri, Robert Lust, and Randolph Chitwood. "Investigation of local heterogeneity of hbO2 and hb in working dog heart in situ under isovolemic hemodilution and critical coronary stenosis." In BiOS Europe '96, edited by Hans-Jochen Foth, Renato Marchesini, and Halina Podbielska. SPIE, 1996. http://dx.doi.org/10.1117/12.260636.

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Arisi, G., E. Macchi, P. Passolunghi, and B. Taccardi. "Independence of ventricular breakthrough sites from pacing site in normal dog hearts." In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1988. http://dx.doi.org/10.1109/iembs.1988.94434.

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Žgank, Žiga, Alenka Nemec Svete, and Vladimira Erjavec. "Blood Lactate, Body Temperature and Heart Rate During Submaximal Exercise in Dogs with Brachycephalic Obstructive Airway Syndrome: A Preliminary Study." In Socratic lectures 6. University of Ljubljana Press, 2022. http://dx.doi.org/10.55295/psl.2021.d.002.

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The aim of the present preliminary study was to investigate how submaximal exercise affects blood lactate (BL) concentrations, body temperature (BT) and heart rate (HR) in dogs with brachycephalic obstructive airway syndrome (BOAS). Seven dogs with BOAS grade 2/3 and 3/3 were subjected to submaximal exercise on a treadmill. Each dog was subjected to training session that began with a 5-minute walk at a speed of 2.5 km/h and an incline of 0% and continued with a 5-minute walk at a speed of 2.5 km/h and at an incline of 5%. Heart rate, BT, and BL concentrations were measured before the start (T1), every 5 minutes during the test (T2, T3) and after 15 and 30 minutes of rest (T4, T5). Blood lactate concentrations at T3 and T5 were significantly lower (P < 0.05) than concentrations at T1. Heart rate and BT values at T2 and T3 were significantly higher (P < 0.05) than values at T1. Submaximal exercise resulted in a significant decrease in BL concentrations and a significant increase in BT and HR in dogs with BOAS. The results of this preliminary study can give us additional information about the severity of BOAS; however, further studies are needed to gain better insight into the physiological response of BOAS patients of individual breeds to submaximal exercise testing.

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Zannad, F., J. Butler, GS Filippatos, et al. "Cardiovascular and Kidney Outcomes with Empagliflozin in Heart Failure." In Diabetes Kongress 2021 – 55. Jahrestagung der DDG. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1727471.

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Reports on the topic "Heart of a dog"

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Chen, Wei-Chen, and Ja Young Hwang. Affect of Dog-Human Companionship to Purchase Criteria of Dog Apparel Across Dog Owner Segments in Taiwan. Iowa State University, Digital Repository, 2017. http://dx.doi.org/10.31274/itaa_proceedings-180814-1916.

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Farronato, Chiara, Jessica Fong, and Andrey Fradkin. Dog Eat Dog: Measuring Network Effects Using a Digital Platform Merger. National Bureau of Economic Research, 2020. http://dx.doi.org/10.3386/w28047.

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Danforth, Lawrence W. One Dog to Kick"". Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada442065.

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Bednarski, J. M. Surficial geology, Dog River, Alberta. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1999. http://dx.doi.org/10.4095/210477.

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Bernales, Rona P., and Ilene S. Basitan. Knowledge, Attitudes and Practices of Dog Owners Regarding Rabies and Dog Bites in Bicol Region. O.I.E (World Organisation for Animal Health), 2015. http://dx.doi.org/10.20506/standz.2790.

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This study was conducted in selected provinces of Bicol Region from April 2015 to May 2015 to describe the knowledge, attitudes and practices (KAP) of dog owners regarding rabies and dog bites. A purposive sampling was used in selecting the respondents of the study. Frequencies were tabulated for all variables. Of the 1,200 respondents, 2,193 dogs were recorded making a 2:1 ratio of dogs to householders in this particular study. Among these dogs 58% were vaccinated against rabies. The majority of the ones taking care of the dogs were female (57.3%) but the primary owner (62.9%) was the head of the family. Only 34.7% of the respondents knew that it is their duty to get their pets vaccinated against rabies. Around one-fourth (20.7%) admitted that someone in their household had been bitten by a dog but most respondents (62.5%) did nothing to the dog. The majority (57.7%) of the bite victims were youths (1-14 years old) and almost all (82.7%) of the wound bites were washed with soap and water. Television (44.9%) was the primary source of knowledge about rabies. The majority of participants (67.3%) said that humans are the main end-hosts that can be infected with rabies. Salivation or drooling (42.7%) and craziness (34.2%) were the main signs cited as behaviour of rabid dogs while craziness (40.2%) and hydrophobia or fear of water (25.4%) were cited for rabid humans. Most (33.9%) do not know the source of rabies but the majority (61.8%) believe that vaccination is the main preventive measure against rabies. The majority of participants (63%) reported that the local ordinances regarding rabies in their locality is about the Local Anti-Rabies Act and almost all (93.2%) admitted that vaccination is the most common anti-rabies program of the government.

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Zhao, Xia, Kim Glenn, Zhiqiang Du, and Max F. Rothschild. Candidate Gene Discovery for Dog Cryptorchidism. Iowa State University, 2008. http://dx.doi.org/10.31274/ans_air-180814-932.

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Pollock, Joshua. Not Coughing, Speaking Through a Dog. Portland State University Library, 2000. http://dx.doi.org/10.15760/etd.7405.

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Perez, Carla Anderson. I Heart Africa. Iowa State University, Digital Repository, 2016. http://dx.doi.org/10.31274/itaa_proceedings-180814-1625.

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Edwards, Ryan. If My Blood Pressure Is High, Do I Take It To Heart? Behavioral Impacts of Biomarker Collection in the Health and Retirement Study. National Bureau of Economic Research, 2013. http://dx.doi.org/10.3386/w19311.

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Ricketts, Stephen R., and Richard E. Miller. Operational experience at a "dog-hair" site. U.S. Department of Agriculture, Forest Service, Pacific Northwest Research Station, 1995. http://dx.doi.org/10.2737/pnw-rn-514.

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