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Journal articles on the topic 'Heat stimulation'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Dill, Stephen G., Robin Gleed, Nora S. Matthews, Hollis N. Erb, and Timothy K. Miller. "Cardiovascular effects of acupuncture stimulation at point Governing Vessel 26 in halothane-anesthetized ponies." American Journal of Veterinary Research 49, no. 10 (1988): 1708–12. https://doi.org/10.2460/ajvr.1988.49.10.1708.

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SUMMARY The acupuncture point Governing Vessel 26 (GV-26) is used commonly in the Orient to treat shock in human beings and other species. The cardiovascular effects of stimulation of GV-26 were studied in healthy ponies during 2 episodes of halothane anesthesia. During one anesthetic episode, electrical stimulation (electrostimulation) of GV-26 was performed, and during the other anesthetic episode, heat stimulation (moxibustion) of GV-26 was performed. The order of the stimulations was random. A nonacupuncture point was selected for comparable control stimulation during each experiment. Cont

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Frahm, Ken Steffen, Carsten Dahl Mørch, and Ole Kæseler Andersen. "Tempo-spatial discrimination to non-noxious stimuli is better than for noxious stimuli." Scandinavian Journal of Pain 16, no. 1 (2017): 171. http://dx.doi.org/10.1016/j.sjpain.2017.04.021.

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Abstract Aims The exteroceptive sensory system is responsible for sensing external stimuli in relation to time and space. The aim of the study was to investigate the tempo-spatial properties of the exteroceptive system using laser heat and mechanical touch stimulation. Methods 13 healthy subjects were stimulated in the volar forearm. Each subject was stimulated using two paradigms, a continuous stimulation along a continuous line on the skin, and a simultaneous 2-point stimulation. The line stimulations were delivered in both a distal and proximal direction with lengths of 25, 50, 75, and 100

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Kim, Hyung Sik, Mi Hyun Choi, Sang Pyo Hong, et al. "A Simple Finger Stimulator for Simultaneous Vibration and Heat Stimulation." Applied Mechanics and Materials 513-517 (February 2014): 3407–10. http://dx.doi.org/10.4028/www.scientific.net/amm.513-517.3407.

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In this study, we developed a simple finger stimulator that can simultaneously control vibration and heat stimulation. The newly developed stimulator consists of three parts, namely the control unit, drive unit, and an actuator. The control unit controls the stimulation type, frequency, intensity, and time. The drive unit amplifies the stimulation signal that drives the actuator. The actuator displays the vibration and heat stimuli quantitatively and simultaneously. Although the developed stimulator is simple, it has a wide frequency range of 0-400 Hz comprising 40 levels, and vibration stimul

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Kim, Hyung Sik, Mi Hyun Choi, In Hwa Lee, et al. "A MR-Compatible Finger Stimulator for Simultaneous Pressure and Heat Stimulation." Applied Mechanics and Materials 610 (August 2014): 182–85. http://dx.doi.org/10.4028/www.scientific.net/amm.610.182.

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In this study, a Magnetic Resonance (MR)-compatible finger stimulator was developed that can display pressure and heat stimulation simultaneously. The developed finger stimulator consists of three parts: a main controller, drive units, and tactors. The main controller controls stimulation parameters such as stimulation intensity and time. The drive units operate pressure and heat tactors in response to commands from the main controller. The tactors display various pressure and heat stimulation quantitatively and simultaneously. The developed stimulator has many advantages in overall system, st

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Zhang, Yingshuai, Yiyong Yang, Jia Cheng, and Linhong Ji. "Research on the cooling garment based on acupoints cold stimulation under a high-temperature environment." FME Transactions 52, no. 3 (2024): 411–18. http://dx.doi.org/10.5937/fme2403411z.

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When the human body experiences heat stress beyond the normal range, it may affect health and work efficiency to a certain extent. This study aimed to investigate the effectiveness of cold stimulation on Dazhui point (GV14), bilateral Xinshu points (B15), bilateral Danshu points (B19), and bilateral Quchi points (LI11) in the body to relieve heat strain in a high-temperature environment. The experiment results showed that the skin temperature (Tskin), tympanic temperature (Tty), heart rate (HR), the physiological strain index based on heart rate (PSIHR), thermal sensation (TS), and thermal com

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Cui, Jian, Cheryl Blaha, and Lawrence I. Sinoway. "Whole body heat stress attenuates the pressure response to muscle metaboreceptor stimulation in humans." Journal of Applied Physiology 121, no. 5 (2016): 1178–86. http://dx.doi.org/10.1152/japplphysiol.00212.2016.

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The effects of whole body heat stress on sympathetic and cardiovascular responses to stimulation of muscle metaboreceptors and mechanoreceptors remains unclear. We examined the muscle sympathetic nerve activity (MSNA), blood pressure, and heart rate in 14 young healthy subjects during fatiguing isometric handgrip exercise, postexercise circulatory occlusion (PECO), and passive muscle stretch during PECO. The protocol was performed under normothermic and whole body heat stress (increase internal temperature ~0.6°C via a heating suit) conditions. Heat stress increased the resting MSNA and heart

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Cui, Jian, Manabu Shibasaki, Scott L. Davis, David A. Low, David M. Keller, and Craig G. Crandall. "Whole body heat stress attenuates baroreflex control of muscle sympathetic nerve activity during postexercise muscle ischemia." Journal of Applied Physiology 106, no. 4 (2009): 1125–31. http://dx.doi.org/10.1152/japplphysiol.00135.2008.

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Both whole body heat stress and stimulation of muscle metabolic receptors activate muscle sympathetic nerve activity (MSNA) through nonbaroreflex pathways. In addition to stimulating muscle metaboreceptors, exercise has the potential to increase internal temperature. Although we and others report that passive whole body heating does not alter the gain of the arterial baroreflex, it is unknown whether increased body temperature, often accompanying exercise, affects baroreflex function when muscle metaboreceptors are stimulated. This project tested the hypothesis that whole body heating alters t

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Oh, Seongwoog, and Jungsuek Oh. "Novel Heat-Mitigating Chip-on-Probe for Brain Stimulation Behavior Experiments." Sensors 20, no. 24 (2020): 7334. http://dx.doi.org/10.3390/s20247334.

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This paper proposes a novel design for a chip-on-probe with the aim of overcoming the heat dissipation effect during brain stimulations using modulated microwave signals. The temperature of the stimulus chip during normal operation is generally 40 °C–60 °C, which is sufficient to cause unintended temperature effects during stimulation. This effect is particularly fatal in brain stimulation applications that require repeated stimulation. This paper proposes, for the first time, a topology that vertically separates the stimulus chip generating the stimulus signal and the probe delivering the sig

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Hiraoka, Nobuyuki, Yuji Arai, Kenji A. Takahashi, et al. "Mild electrical stimulation with heat stimulation increase heat shock protein 70 in articular chondrocyte." Journal of Orthopaedic Research 31, no. 6 (2013): 894–900. http://dx.doi.org/10.1002/jor.22307.

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10

Oono, Y., H. Kubo, T. Imamura, et al. "The subjective sensation induced by various thermal pulse stimulation in healthy volunteers." Scandinavian Journal of Pain 16, no. 1 (2017): 177–78. http://dx.doi.org/10.1016/j.sjpain.2017.04.039.

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AbstractAimsNovel quantitative thermal stimulator devices (QTSDs) have been developed to deliver thermal pulse stimulation with regulated constant temperatures (0–45°C) with a Peltier element probe (16 cm2). The aim of this study was to investigate subjective sensation induced by the interaction between simultaneously applied painful cold and heat stimuli in various sites.MethodsTwenty healthy subjects (12 men and 8 women, age range: 25–45 years) participated. The intensity of cold pain (CP) and heat pain (HP) stimuli were assessed by visual analogue scale (VAS) and adjusted to elicit approxim

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Jones, S. L., and G. F. Gebhart. "Quantitative characterization of ceruleospinal inhibition of nociceptive transmission in the rat." Journal of Neurophysiology 56, no. 5 (1986): 1397–410. http://dx.doi.org/10.1152/jn.1986.56.5.1397.

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A total of 51 dorsal horn units responsive to heat were isolated and their receptive fields characterized (i.e., response properties and adequate stimuli determined) in pentobarbital-anesthetized, paralyzed rats. In 39 of the 51 units, the descending inhibition of heat-evoked activity produced by focal electrical stimulation in the locus ceruleus/subceruleus (LC/SC) was examined. All units studied responded to mechanical stimulation, to electrical stimulation of the ipsilateral tibial nerve at intensities supramaximal to activate A-alpha, delta- and C-fibers, and to noxious heating (50 degrees

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Mizumura, K., J. Sato, and T. Kumazawa. "Strong heat stimulation sensitizes the heat response as well as the bradykinin response of visceral polymodal receptors." Journal of Neurophysiology 68, no. 4 (1992): 1209–15. http://dx.doi.org/10.1152/jn.1992.68.4.1209.

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1. Hyperalgesia after thermal injury is a common phenomenon, but its mechanism is poorly understood. As a step toward understanding the mechanism for heat sensitization, we searched conditions that would induce sensitization consistently and studied changes in polymodal receptors in their responses to heat (45 and 48 degrees C) and to bradykinin. Experiments were conducted in vitro, with the use of testis-superior spermatic nerve preparations excised from anesthetized dogs. 2. Stimulation at 55 degrees C for 30 s induced clear augmentation of the responses to stimulations at 45 and 48 degrees

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Myoung, Hyoun-Seok, and Kyoung-Joung Lee. "A Unique Electrical Thermal Stimulation System Comparable to Moxibustion of Subcutaneous Tissue." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/518313.

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Moxibustion strengthens immunity and it is an effective treatment modality, but, depending on the material quantity, shape, and composition, the thermal strength and intensity can be difficult to control, which may cause pain or epidermal burns. To overcome these limitations, a heat stimulating system which is able to control the thermal intensity was developed. The temperature distributions on epidermis, at 5 mm and 10 mm of depth, in rabbit femoral tissue were compared between moxibustion and the electric thermal stimulation system. The stimulation system consists of a high radio frequency d

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Koda, Hisashi, and Kazue Mizumura. "Sensitization to Mechanical Stimulation by Inflammatory Mediators and by Mild Burn in Canine Visceral Nociceptors In Vitro." Journal of Neurophysiology 87, no. 4 (2002): 2043–51. http://dx.doi.org/10.1152/jn.00593.2001.

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Hyperalgesia to mechanical stimulation and heat is commonly observed in inflamed conditions. Although sensitization to heat is well documented and its mechanism has also been well studied, it remains unclear whether and how nociceptors are sensitized to mechanical stimulation. Therefore we conducted in vitro investigation of which inflammatory mediators (bradykinin, histamine, prostaglandin E2, and protons) sensitize nociceptors to suprathreshold mechanical stimulation and at what concentrations. In addition, we studied the effects of possible second messengers for these mediators downstream o

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Petrofsky, Jerrold, Michael Laymon, and Haneul Lee. "Low Level Continuous Heat Wraps can Increase the Efficiency of Transcutaneous Electrical Nerve Stimulation for Pain Management." Physikalische Medizin, Rehabilitationsmedizin, Kurortmedizin 30, no. 05 (2020): 290–98. http://dx.doi.org/10.1055/a-1126-4436.

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AbstractBoth transcutaneous electrical nerve stimulation and superficial heat have been used for pain management. While heat has been shown to have a beneficial effect on pain, transcutaneous electrical nerve stimulation remains controversial. The purpose of the present study was to see if heat, when added to transcutaneous electrical nerve stimulation, would provide more consistent relief. A total of 180 subjects participated in this study and were randomly divided into 12 groups. Low level continuous heat was applied while electrical stimulation was applied at 2 intensities, 2 frequencies an

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Mauderli, Andre P., Charles J. Vierck, Richard L. Cannon, Anthony Rodrigues, and Chiayi Shen. "Relationships Between Skin Temperature and Temporal Summation of Heat and Cold Pain." Journal of Neurophysiology 90, no. 1 (2003): 100–109. http://dx.doi.org/10.1152/jn.01066.2002.

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Temporal summation of heat pain during repetitive stimulation is dependent on C nociceptor activation of central N-methyl-d-aspartate (NMDA) receptor mechanisms. Moderate temporal summation is produced by sequential triangular ramps of stimulation that control skin temperature between heat pulses but do not elicit distinct first and second pain sensations. Dramatic summation of second pain is produced by repeated contact of the skin with a preheated thermode, but skin temperature between taps is not controlled by this procedure. Therefore relationships between recordings of skin temperature an

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Takigawa, Mizuki, Fraidoon Rahmanzai, Rio Kita, and Shigeyuki Date. "Basic Research of Improving the Mortar Flow by Thermal Stimulation to Superplasticizer." MATEC Web of Conferences 278 (2019): 01003. http://dx.doi.org/10.1051/matecconf/201927801003.

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Polycarboxylic acid-based superplasticizers are being used for various fields of concrete work, however little has reported on changing basic performance by thermal fluctuation. In this study, heating superplasticizers itself is hereinafter as referred to as “thermal stimulation”, the effect of thermal stimulation and heat retention of superplasticizer on the fresh mortar, moreover the influence of molecular structural changed of superplasticizer by thermal stimulation were investigated. As the result, it was confirmed that improving fluidity of the mortar flow on this condition the highly hea

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Haddeland, Unni, Knut Sletten, Anne Bennick, Willem Nieuwenhuizen, and Frank Brosstad. "Aggregated, Conformationally Changed Fibrinogen Exposes the Stimulating Sites for t-PA-Catalysed Plasminogen Activation." Thrombosis and Haemostasis 75, no. 02 (1996): 326–31. http://dx.doi.org/10.1055/s-0038-1650269.

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SummaryThe present paper shows that conformationally changed fibrinogen can expose the sites Aα-(148-160) and γ-(312-324) involved in stimulation of the tissue-type plasminogen activator (t-PA)-catalysed plasminogen activation. The exposure of the stimulating sites was determined by ELISA using mABs directed to these sites, and was shown to coincide with stimulation of t-PA-catalysed plasminogen activation as assessed in an assay using a chromogenic substrate for plasmin. Gel permeation chromatography of fibrinogen conformationally changed by heat (46.5° C for 25 min) demonstrated the presence

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Jones, S. L., and G. F. Gebhart. "Spinal pathways mediating tonic, coeruleospinal, and raphe-spinal descending inhibition in the rat." Journal of Neurophysiology 58, no. 1 (1987): 138–59. http://dx.doi.org/10.1152/jn.1987.58.1.138.

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1. The contribution of midline medullary bulbospinal neurons to descending inhibition from the locus coeruleus (LC) and the funicular trajectories of coeruleo- and raphe-spinal fibers mediating inhibition of spinal nociceptive transmission were examined in different experiments. Extracellular recordings of lumbar dorsal horn neurons were made in deeply pentobarbital-anesthetized, paralyzed rats. All units studied responded to electrical stimulation of the ipsilateral tibial nerve at intensities supramaximal to activate A-alpha-delta- and C-fibers and to mechanical and heat (50 degrees C) stimu

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Manjunath, R., and T. Ramasarma. "Stimulation of liver tryptophan pyrrolase during heat exposure." Biochemical Journal 226, no. 2 (1985): 397–402. http://dx.doi.org/10.1042/bj2260397.

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Exposure of rats to heat (39 +/- 1 degree C) stimulated liver tryptophan pyrrolase 2-fold between 3 and 48 h. Plasma corticosterone increased 2-fold after 1 h of heat exposure and decreased to a low value of 50% by 16 h. The effect of heat exposure on the enzyme was obtained in adrenalectomized animals. Stimulation by cortisol and tryptophan of the enzyme was also obtained in heat exposure, and the effects seemed to be additive. The concentration of tryptophan in the liver remained unchanged, and that in the plasma decreased to about 50% at 8 h exposure to heat and reverted to normal by 46 h.

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Ho, Tseng-Fung, Hsin-Han Tsai, Chi-Chih Chuang, et al. "Thermal Comfort Model Established by Using Machine Learning Strategies Based on Physiological Parameters in Hot and Cold Environments." Indoor Air 2024 (January 19, 2024): 1–16. http://dx.doi.org/10.1155/2024/9427822.

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The air-conditioning systems have become an indispensable part of our daily life for keeping the quality of life. However, to improve the thermal comfort and reduce energy consumption is crucial to use the air conditioners effectively with rapid development of artificial intelligence technology. This study explored the correlation between the response of human physiological parameters and thermal sensation voting (TSV) to evaluate the comfort level among various cold and hot stimulations. The variations of the three physiological parameters, which were body surface temperature, skin blood flow

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Wähner, M., and M. Richter. "Influence of cycle stimulation in weaned sows on fertility depend on season." Biotehnologija u stocarstvu 27, no. 3 (2011): 521–31. http://dx.doi.org/10.2298/bah1103521w.

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In summer high temperatures are stress for sows mostly. This situation often affects the reproduction physiology in animals strongly. As a result of that the fertility and reproduction performance of sows can be reduced. High environmental temperatures and especially heat accumulation in body of the animals affect the metabolism in high performance sows. That is important in very sensitive phases in reproduction cycle of sows like heat, pregnancy and lactation. Young sows (gilts and primiparous sows) are more sensitive than older sows. This situation demands zoo- and biotechnical activities ex

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Morimoto, A., N. Murakami, T. Ono, T. Watanabe, and Y. Sakata. "Stimulation of ventromedial hypothalamus induces cold defense responses in conscious rabbits." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 250, no. 4 (1986): R560—R566. http://dx.doi.org/10.1152/ajpregu.1986.250.4.r560.

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The involvement of the ventromedial hypothalamus (VMH) in thermoregulatory responses, which include heat production and heat loss responses, was investigated by the method of electrical stimulation. Electrical stimulation of the VMH caused a rise in rectal temperature, accompanied by the enhancement of heat production: O2 consumption and shivering. In addition, a reduction in heat loss was observed, including decreases in skin temperature (Ts), respiratory rate, and body surface area resulting from a huddled posture. In this study, stimulation of the lateral hypothalamus and other regions near

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Alpizar, Yeranddy A., Brett Boonen, Maarten Gees, et al. "Allyl isothiocyanate sensitizes TRPV1 to heat stimulation." Pflügers Archiv - European Journal of Physiology 466, no. 3 (2013): 507–15. http://dx.doi.org/10.1007/s00424-013-1334-9.

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Boucher, Natalie, Johanne Harnois, and Robert Carpentier. "Heat-stress stimulation of electron flow in a photosystem I submembrane fraction." Biochemistry and Cell Biology 68, no. 7-8 (1990): 999–1004. http://dx.doi.org/10.1139/o90-147.

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Oxygen uptake using methyl viologen as the terminal electron acceptor was recorded in digitonin-derived photosystem I submembrane fractions incubated at either 25 or 50 °C. A two- to four-fold heat-stress stimulation of electron flow was detected at 50 °C when reduced 2,6-dichlorophenol-indophenol was used as the primary electron donor. However, no stimulation was seen with N,N,N′,N′ -tetramethylphenylenediamine as the donor. The stimulation was enhanced by specific cations (Mg2+, Na+, K+), but not by Mn2 or Ca2+. The enhancement obtained with Mg2+ could be eliminated by incubating for a prolo

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Miaron, J. O. O., R. J. Christopherson, and R. T. Hardin. "The effect of alpha2-adrenoceptor stimulation with guanfacin on thermogenesis in fasted and fed sheep." Canadian Journal of Animal Science 75, no. 4 (1995): 537–42. http://dx.doi.org/10.4141/cjas95-081.

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Eight sheep with an average body weight of 99 kg were divided into two groups (fasted and fed) of four and kept in individual pens. The sheep were used to examine the effects of alpha2-adrenoceptor stimulation on heat production, heart rate, rectal temperature, skin temperature and plasma parameters. On the day of the experiment, food but not water was withheld from the fasted group and the fed group received 1.0 kg of pelleted alfalfa diet. The treatments consisting of vehicle (saline) and three levels (low = 0.8 mg; medium = 1.6 mg; high = 2.4 mg per sheep) of guanfacin were administered int

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Xie, Dingyi, Zhongyong Liu, Xiaoqin Hou, et al. "Heat Sensitisation in Suspended Moxibustion: Features and Clinical Relevance." Acupuncture in Medicine 31, no. 4 (2013): 422–24. http://dx.doi.org/10.1136/acupmed-2013-010409.

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We have observed a ‘heat-sensitisation’ phenomenon in a large proportion of patients receiving suspended moxibustion treatment. Patients become thermally sensitised to moxibustion stimulation at certain locations on the body, indicated by sensations of strong warmth or heat penetrating into the body (heat penetration), warmth spreading around the stimulation site (heat expansion), warmth conducting in certain directions and reaching some body regions or even internal organs remote from stimulation sites (heat transmission), or other non-thermal sensations such as aching, heaviness, pressure et

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Riccio, Daniele, Silvia Lo Vecchio, and Lars Arendt-Nielsen. "The effect of escalating heat stimulation on top of anesthetized skin." Itch 8, no. 1 (2023): e65-e65. http://dx.doi.org/10.1097/itx.0000000000000065.

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The relationship between itch and heat pain has been vastly explored. A 70-year-old study, showed the development of paradoxical itch following heat stimulation of anesthetized skin. The aim of this study was to re-evaluate, with more modern technologies and systematic approaches, this paradoxical itch effect. Escalating heat stimuli were applied to the local anesthetized skin of 19 healthy subjects, itch, and pain intensities were continuously assessed during the stimulation. As expected, pain sensation was significantly reduced by local intradermal anesthesia, however, no paradoxical itch se

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Noll, Kyle, Priscella Asman, Katherine Connelly, et al. "NCOG-14. INTRAOPERATIVE COGNITIVE-LINGUISTIC MAPPING GUIDED BY VISUALIZATION OF GAMMA BAND MODULATION ELECTROCORTICOGRAMS: PROOF OF CONCEPT IN A PATIENT WITH LEFT TEMPORAL AND OCCIPITAL LOW-GRADE ASTROCYTOMA." Neuro-Oncology 24, Supplement_7 (2022): vii200. http://dx.doi.org/10.1093/neuonc/noac209.767.

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Abstract OBJECTIVE Determine the feasibility and preliminary utility of a novel approach to intraoperative brain mapping guided by visualization of electrocorticography (ECoG) heat maps. METHODS A 39-year-old male with a biopsy-proven left posterior temporal and occipital WHO grade II IDH-mutant astrocytoma underwent awake craniotomy with intraoperative language mapping. Language mapping utilized a dual iPad stimulus presentation system (NeuroMapper) coupled to a portable real-time neural signal processing system capable of both recording cortical activity and delivering direct cortical stimul

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Thornhill, J., A. Jugnauth, and I. Halvorson. "Brown adipose tissue thermogenesis evoked by medial preoptic stimulation is mediated via the ventromedial hypothalamic nucleus." Canadian Journal of Physiology and Pharmacology 72, no. 9 (1994): 1042–48. http://dx.doi.org/10.1139/y94-146.

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Experiments were designed to determine if a functional ventromedial hypothalamic nucleus was required for the activation of brown adipose tissue thermogenesis evoked by medial preoptic stimulation. Male, urethane-anesthetized Long–Evans rats, maintained at 37 °C, had temperatures (thermistor probes for gastrocnemius, Tm; intrascapular brown adipose tissue, 7IBAT; colonic, Tc; and tail, Tt), gastrocnemius electromyogram activity (via stainless steel recording electrodes), and systemic blood pressure and heart rate (via a femoral arterial catheter) measured before and after a series of unilatera

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Mizumura, K., J. Sato, M. Minagawa, and T. Kumazawa. "Incomplete suppressive effects of acetylsalicylic acid on the heat sensitization of canine testicular polymodal receptor activities." Journal of Neurophysiology 72, no. 6 (1994): 2729–36. http://dx.doi.org/10.1152/jn.1994.72.6.2729.

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1. Using canine testis-spermatic nerve preparations in vitro, we studied the effects of acetylsalicylic acid (ASA), an inhibitor of cyclooxygenase, on the polymodal receptor response to heat stimulation itself and on the sensitizing effects on the heat and bradykinin responses induced by strong heat stimulation (55 degrees C for 30 s). 2. Greater heat responses tended to be strongly suppressed by ASA (550 microM), with a significant correlation observed between the response magnitude and the magnitude of the suppression (r = 0.88 for the response at 45 degrees C; r = 0.83 for the response at 4

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Brink, Thaddeus S., and Peggy Mason. "Raphe Magnus Neurons Respond to Noxious Colorectal Distension." Journal of Neurophysiology 89, no. 5 (2003): 2506–15. http://dx.doi.org/10.1152/jn.00825.2002.

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First published November 13, 2002; 10.1152/jn.00825.2002. Physiological studies of neurons in raphe magnus (RM) and the adjacent nucleus reticularis magnocellularis (NRMC) have demonstrated that the response to noxious cutaneous stimulation predicts the response to opioid administration and therefore a cell's functional role in nociceptive modulation. Although visceral stimulation, like opioids, elicits antinociception, little is known about how RM and NRMC cells respond to visceral stimulation. Therefore RM and NRMC cells were tested for their responses to both colorectal distension (CRD) and

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Teng, Wang, He, and Chen. "Mathematical Modeling and Simulation on the Stimulation Interactions in Coalbed Methane Thermal Recovery." Processes 7, no. 8 (2019): 526. http://dx.doi.org/10.3390/pr7080526.

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Heat stimulation of coalbed methane (CBM) reservoirs has remarkable promotion to gas desorption that enhances gas recovery. However, coalbed deformation, methane delivery and heat transport interplay each other during the stimulation process. This paper experimentally validated the evolutions of gas sorption and coal permeability under variable temperature. Then, a completely coupled heat-gas-coal model was theoretically developed and applied to a computational simulation of CBM thermal recovery based on a finite element approach of COMSOL with MATLAB. Modeling and simulation results show that

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Hugosdottir, Rosa, Mindy Kasting, Carsten Dahl Mørch, Ole Kæseler Andersen, and Lars Arendt-Nielsen. "Priming of central and peripheral mechanisms with heat and cutaneous capsaicin facilitates secondary hyperalgesia to high-frequency electrical stimulation." Journal of Neurophysiology 127, no. 3 (2022): 651–59. http://dx.doi.org/10.1152/jn.00154.2021.

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High-frequency electrical stimulation (HFS) and heat/capsaicin sensitization are well-known models of secondary hyperalgesia. The results from the current study indicate that increased sensitivity to 128 mN pin-prick stimulation can be obtained when HFS is delivered following an already established heightened central hyperexcitability provoked by heat/capsaicin sensitization.

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Lin, Chih-Hsueh, Zhi-Hao Wang, and Gwo-Jia Jong. "A research on relevance between photoplethysmography signal and perceptual stimulation." International Journal of Modern Physics B 34, no. 22n24 (2020): 2040129. http://dx.doi.org/10.1142/s0217979220401293.

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In this paper, the Photoplethysmography (PPG) signal response of humans under different perceptual stimuli was mainly discussed. The autonomic nervous system (ANS) regulates the functioning of organs or tissues in the body to make the body adapt to the environment. When the human body is stimulated, it can obtain information about ANS from the analysis results of heart rate variability (HRV).The proposed method is used with PPG signals for time domain and frequency domain analysis to obtain HRV parameters and short-time Fourier transform (STFT) output heat map, respectively. Different environm

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Casey, Kenneth L., Thomas J. Morrow, Jürgen Lorenz, and Satoshi Minoshima. "Temporal and Spatial Dynamics of Human Forebrain Activity During Heat Pain: Analysis by Positron Emission Tomography." Journal of Neurophysiology 85, no. 2 (2001): 951–59. http://dx.doi.org/10.1152/jn.2001.85.2.951.

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To learn about the sequence of brain activation patterns during heat pain, we acquired positron emission tomographic (PET) brain scans at different times during repetitive heat stimulation (40 or 50°C; 5-s contact) of each subject's left forearm. Early scans began at the onset of 60 s of stimulation; late scans began after 40 s of stimulation, which continued throughout the 60-s scan period (total stimulus duration 100 s). Each subject (14 normal, right-handed subjects; 10 male, 4 female; ages 18–42) used a visual analog scale to rate the perceived stimulus intensity (0 = no heat, 7 = pain thr

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van Furth, A. Marceline, Els M. Verhard-Seijmonsbergen, Jan A. M. Langermans, Jaap T. van Dissel, and Ralph van Furth. "Anti-CD14 Monoclonal Antibodies Inhibit the Production of Tumor Necrosis Factor Alpha and Interleukin-10 by Human Monocytes Stimulated with Killed and Live Haemophilus influenzae or Streptococcus pneumoniaeOrganisms." Infection and Immunity 67, no. 8 (1999): 3714–18. http://dx.doi.org/10.1128/iai.67.8.3714-3718.1999.

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ABSTRACT In previous studies, we have shown that intact, heat-killed, gram-negative bacteria (GNB) and gram-positive bacteria (GPB) can stimulate the production of various proinflammatory and anti-inflammatory cytokines. The objective of the present study was to investigate whether the production of tumor necrosis factor alpha (TNF) and interleukin-10 (IL-10) by human monocytes stimulated by intact heat-killed or live Haemophilus influenzae orStreptococcus pneumoniae is mediated by CD14. Two anti-CD14 monoclonal antibodies (MAbs) were used to study the interaction between human monocytes and b

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Frahm, K. S., O. K. Andersen, L. Arendt-Nielsen, and C. D. Mørch. "Offset analgesia evoked by non-contact thermal stimulator." Scandinavian Journal of Pain 1, no. 3 (2010): 169–70. http://dx.doi.org/10.1016/j.sjpain.2010.05.009.

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AbstractObjectiveThe objective of this study was to test if offset analgesia could be evoked using a noncontact thermal stimulator. Offset analgesia [J. Neurophysiol. 87:2205–2208, 2002] is defined as an unproportionally large decrease in pain intensity following a slight decrease in stimulation intensity. The importance of differences in thermal properties between human hairy and glabrous skin was investigated.MethodsA 20W diode laser (970 nm) was used for the thermal stimulation. A fast (50 images/s) infrared camera measured the skin temperature and a temperature controlled feedback control

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Shea, V. K., and E. R. Perl. "Sensory receptors with unmyelinated (C) fibers innervating the skin of the rabbit's ear." Journal of Neurophysiology 54, no. 3 (1985): 491–501. http://dx.doi.org/10.1152/jn.1985.54.3.491.

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The cutaneous receptive properties of unmyelinated (C) fibers of the rabbit's great auricular nerve were determined by single-unit recordings. The majority of C-fiber units could be excited by cutaneous stimulation, and such sensory units fell into three major categories on the basis of responses to mechanical and thermal stimulation of their cutaneous receptive fields: low-threshold mechanoreceptors, nociceptors, or specific thermoreceptors. The majority of afferent elements were nociceptive, and all nociceptors responded to strong mechanical stimulation. Three types of nociceptors could be d

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Sagalajev, Boriss, Hanna Viisanen, Hong Wei, and Antti Pertovaara. "Descending antinociception induced by secondary somatosensory cortex stimulation in experimental neuropathy: role of the medullospinal serotonergic pathway." Journal of Neurophysiology 117, no. 3 (2017): 1200–1214. http://dx.doi.org/10.1152/jn.00836.2016.

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Stimulation of the secondary somatosensory cortex (S2) has attenuated pain in humans and inflammatory nociception in animals. Here we studied S2 stimulation-induced antinociception and its underlying mechanisms in an experimental animal model of neuropathy induced by spinal nerve ligation (SNL). Effect of S2 stimulation on heat-evoked limb withdrawal latency was assessed in lightly anesthetized rats that were divided into three groups based on prior surgery and monofilament testing before induction of anesthesia: 1) sham-operated group and 2) hypersensitive and 3) nonhypersensitive (mechanical

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Filho, Ramiro Oliveira, Gustavo Azevedo de Mello, Victor Mendonça Pereira, Jose Luiz Moraes Vasconcelos, Reinaldo F. Cooke, and Ky Pohler. "PSII-38 The effect of clitoral stimulation post fixed-time insemination in Bos indicus beef cattle." Journal of Animal Science 97, Supplement_3 (2019): 218–19. http://dx.doi.org/10.1093/jas/skz258.448.

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Abstract The objective of this experiment was to evaluate the effect of clitoral stimulation post-insemination on pregnancy rates in Bos indicus beef cattle. A total of 1186 multiparous Nelore cows were assigned to an estradiol-based estrus synchronization + timed-AI protocol (FTAI, d 0), and randomly assigned to receive either 2 to 5 seconds of clitoral stimulation or no clitoral stimulation after artificial insemination. Estrus expression prior to AI was evaluated based on patch activation (estrus, ≥ 50% activated; no estrus, &lt; 50% activated) using Estrotect Heat Detector and chute ex

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Sato, F., M. Owen, R. Matthes, K. Sato, and C. V. Gisolfi. "Functional and morphological changes in the eccrine sweat gland with heat acclimation." Journal of Applied Physiology 69, no. 1 (1990): 232–36. http://dx.doi.org/10.1152/jappl.1990.69.1.232.

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Three adult male patas monkeys (11-15 kg) were heat acclimated by continuous exposure to an ambient temperature of 33 +/- 1 degree C at 13% relative humidity for 9 mo. During the last month, they were also exposed to 45 degrees C at 10% relative humidity for 4 h/day and 5 days/wk. Before and after 3 wk of acclimation, the animals were given a heat-tolerance test in which rectal (Tre) and mean skin (Tsk) temperatures, heart rate, and sweat rate (msw) were monitored during a 90-min exposure to 45 degrees C heat with 24% relative humidity under lenperone (1.0-1.4 mg/kg im) tranquilization. Maxima

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Schoene, Mark L. "Heat and Electrical Muscle Stimulation Add Little Value." Lippincott's Bone and Joint Newsletter 9, no. 6 (2003): 61. http://dx.doi.org/10.1097/01300517-200306000-00002.

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Alexandrov, V. Ya, I. S. Gorban', and A. G. Lomagin. "On Heat-Shock Stimulation of Plant Cells Reparability." Biochemie und Physiologie der Pflanzen 188, no. 5 (1992): 333–42. http://dx.doi.org/10.1016/s0015-3796(11)80128-9.

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Nakae, Aya, Takahiro Soshi, Yumi Tsugita, Chie Kishimoto, and Kosuke Kato. "Objective evaluation of pain using experimental heat stimulation." PAIN RESEARCH 33, no. 1 (2018): 40–46. http://dx.doi.org/10.11154/pain.33.40.

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Alavi Fazel, S. A., and E. Lorzadeh. "Pool boiling heat transfer intensification by electro-stimulation." Chemical Engineering and Processing - Process Intensification 149 (March 2020): 107818. http://dx.doi.org/10.1016/j.cep.2020.107818.

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Motsnyj, M. P., N. P. Botsva, S. V. Vlasova, О. V. Elina та I. P. Matvij. "Вплив термічної стимуляції на біопотенціали листя кукурудзи". Visnyk of Dnipropetrovsk University. Biology, medicine 1, № 2 (2010): 65–70. http://dx.doi.org/10.15421/021028.

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Dynamics of maize leaves' biopotentials evoked by cold- and heat stimuli with two frequencies 0.05 and 0.1 Hz is analyzed. Potential amplitude dependence of heating rate and time interval between first and following stimuli during both heating and cooling was discovered. It is ascertained that following potentials' amplitude increases in time during heat stimulation and decreases in time during cold stimulation. Qualitative difference in the reaching of potential stabilization is established for both stimulation frequencies; and probable reasons of the difference are analyzed. Potential stabil

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Koh, Young Jun, Ju-Hee Lee, and Sung Yun Park. "Moxibustion-Simulating Bipolar Radiofrequency Suppresses Weight Gain and Induces Adipose Tissue Browning via Activation of UCP1 and FGF21 in a Mouse Model of Diet-Induced Obesity." Evidence-Based Complementary and Alternative Medicine 2018 (September 10, 2018): 1–12. http://dx.doi.org/10.1155/2018/4737515.

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Background. Obesity is a pathological condition associated with various diseases including diabetes, stroke, arthritis, infertility, and heart disease. Moxibustion is widely used to prevent and manage obesity in traditional Asian medicine. We tested our hypothesis that moxibustion-simulating bipolar radiofrequency (M-RF) can suppress total body and white adipose tissue (WAT) weight gain via induction of WAT browning in a mouse model of diet-induced obesity (DIO). Methods. We designed an M-RF device that could accurately adjust the depth and temperature at which heat stimulation was administere

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Rahmanzai, Faraidoon, Ghawsaddin Nazari, Mizuki Takigawa, and Shigeyuki Date. "Combined Effect of Thermal Stimulated Superplasticizer with BFS on Fresh and Hardened Property of Mortar." Materials Science Forum 936 (October 2018): 224–29. http://dx.doi.org/10.4028/www.scientific.net/msf.936.224.

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Usage of mineral and chemical admixtures in concrete or mortar is a usual solution to reach full compaction mainly where reinforcement blockage and the shortage of skilled labors happen. Super Plasticizers have become essential ingredients of any designed concrete mix today. Property of fresh and hardened concrete is strongly influenced by the interaction of mineral and chemical admixtures. This paper has been made to evaluate effect of heat stimulation of with two types of Polycarboxylic acid-based ether superplasticizer, pre-cast (SP2) type and ready-mix (SP1) type superplasticizer (SP) with

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Buono, Michael J., Travis R. Numan, Ryan M. Claros, Stephanie K. Brodine, and Fred W. Kolkhorst. "Is active sweating during heat acclimation required for improvements in peripheral sweat gland function?" American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 297, no. 4 (2009): R1082—R1085. http://dx.doi.org/10.1152/ajpregu.00253.2009.

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We investigated whether the eccrine sweat glands must actively produce sweat during heat acclimation if they are to adapt and increase their capacity to sweat. Eight volunteers received intradermal injections of BOTOX, to prevent neural stimulation and sweat production of the sweat glands during heat acclimation, and saline injections as a control in the contralateral forearm. Subjects performed 90 min of moderate-intensity exercise in the heat (35°C, 40% relative humidity) on 10 consecutive days. Heat acclimation decreased end-exercise heart rate (156 ± 22 vs. 138 ± 17 beats/min; P = 0.0001)

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