Academic literature on the topic 'HeLa cancer Cell'

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Journal articles on the topic "HeLa cancer Cell"

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Zhang, Junhua, Xingbo Tian, Huifang Yin, et al. "TXNIP induced by MondoA, rather than ChREBP, suppresses cervical cancer cell proliferation, migration and invasion." Journal of Biochemistry 167, no. 4 (2019): 371–77. http://dx.doi.org/10.1093/jb/mvz105.

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Abstract Evidence has indicated the associations between thioredoxin-interacting protein (TXNIP) and cancers. However, the role of TXNIP in cervical cancer remains unclear. Hence, this study aims to investigate the role of TXNIP in regulating cervical cancer cell proliferation, migration and invasion. TXNIP expression can be regulated by either MondoA or ChREBP in a cell- or tissue- dependent manner. Thus, we also explored whether TXNIP expression in cervical cancer can be regulated by MondoA or ChREBP. Our results showed that TXNIP expression was decreased in cervical cancer cells (HeLa, SiHa
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Rahmaddiansyah, Refa, Suci Hasani, Azizah Amatu Zikrah, and Dessy Arisanty. "The Effect of Gambier Catechin Isolate on Cervical Cancer Cell Death (HeLa Cell Lines)." Open Access Macedonian Journal of Medical Sciences 10, B (2022): 1293–97. http://dx.doi.org/10.3889/oamjms.2022.8779.

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BACKGROUND: Cervical cancer is the second most common type of cancer in women worldwide. Human Papilloma Virus infection on the surface of the cervix is the most common cause which can cause abnormal growth of cervical cells.
 AIM: This research was conducted in vitro which aims to determine whether catechin compounds can inhibit the growth and regulation of cervical cancer cells (HeLa cell line).
 METHODS: This is experimental research using the colourimetric assay method and qualitative observation of cervical cancer cell morphology (HeLa cell line) under a fluorescence microscope.
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Rajan, Teena, Benluvankar V, and Vincent S. "SACCHAROMYCES CEREVISIAE-INDUCED APOPTOSIS OF MONOLAYER CERVICAL CANCER CELLS." Asian Journal of Pharmaceutical and Clinical Research 10, no. 8 (2017): 63. http://dx.doi.org/10.22159/ajpcr.2017.v10i8.18818.

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Objective: The present study was undertaken to examine the effect of phagocytosis of killed yeast on the induction of apoptosis in monolayer of HeLa cells.Methods: HeLa cell line was incubated with different doses (1000-7.8 μg/ml) of heat-killed Saccharomyces cerevisiae for 24, 48, and 72 hrs. The cytotoxicity against HeLa cell line during different exposure hours was screened by 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-tetrazolium bromide assay. Induction of apoptosis was further confirmed by morphological and biochemical examination. Antiproliferative effect of yeast was examined under in
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Yadav, Sunny, Devashree Jahagirdar, Mamta Shekhawat, and Nilesh Kumar Sharma. "Induction of S-phase Cell Cycle Arrest and Apoptosis in HeLa Cells by Small RNAs Fraction ofSolanum tuberosumL." MicroRNA 8, no. 3 (2019): 180–88. http://dx.doi.org/10.2174/2211536608666181218114254.

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Background:In cancer therapeutics, several new classes of small molecules based targeted drug options are reported including peptide mimetic and small RNAs therapeutics.Objective:Small RNAs represent a class of short non-coding endogenous RNAs that play an important role in transcriptional and post transcriptional gene regulation among varied types of species including plants and animals.Methods:To address the role of small RNAs from plant sources upon cancer cells, authors report on the effects of small RNAs fraction of potato in in-vitro model of human derived HeLa cancer cells. This paper r
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Yang, Fan, Juan Zhang, Biao Xian, et al. "Effect of trichostatin A on biological characteristics of side population cells of cervical cancer cell line (HeLa)." Tropical Journal of Pharmaceutical Research 22, no. 8 (2023): 1613–17. http://dx.doi.org/10.4314/tjpr.v22i8.12.

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Purpose: To investigate the effect of trichostatin A (TSA) on biological characteristics of side population (SP) cells of cervical cancer cell line (HeLa)Methods: Side population (SP) and NSP cells were obtained from 6th generation of primary cervical cancer cells and cervical cancer cell line (HeLa). Cell surface markers (ATP-binding membrane transporter superfamily G member 2 (ABCG2), CD133, CD43, p63, Ki67, multidrug resistance (MDR) as well as cell cycle phase distribution and apoptosis, were determined. SP cells in HeLa were divided into 3 groups that received TSA at doses of 0.01, 0.05,
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Wang, Xiufen, Yucui Xie, and Jing Wang. "[ARTICLE WITHDRAWN] Overexpression of MicroRNA-34a-5p Inhibits Proliferation and Promotes Apoptosis of Human Cervical Cancer Cells by Downregulation of Bcl-2." Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 26, no. 6 (2018): 977–85. http://dx.doi.org/10.3727/096504017x15037506066252.

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Aberrant expressions of microRNAs (miRNAs) are involved in the development and progression of various types of cancers. In this study, we investigated the roles of miR-34a-5p in the proliferation, migration, invasion, and apoptosis of cervical cancer cells (HeLa cells). We found that overexpression of miR-34a-5p significantly inhibited the viability, migration, and invasion of HeLa cells, but promoted cell apoptosis. Suppression of miR-34a-5p showed opposite effects. The mRNA and protein expression levels of Bcl-2 in HeLa cells were increased by miR-34a-5p suppression but decreased by miR-34a-
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Lucey, Brendan P., Walter A. Nelson-Rees, and Grover M. Hutchins. "Henrietta Lacks, HeLa Cells, and Cell Culture Contamination." Archives of Pathology & Laboratory Medicine 133, no. 9 (2009): 1463–67. http://dx.doi.org/10.5858/133.9.1463.

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Abstract Henrietta Lacks died in 1951 of an aggressive adenocarcinoma of the cervix. A tissue biopsy obtained for diagnostic evaluation yielded additional tissue for Dr George O. Gey's tissue culture laboratory at Johns Hopkins (Baltimore, Maryland). The cancer cells, now called HeLa cells, grew rapidly in cell culture and became the first human cell line. HeLa cells were used by researchers around the world. However, 20 years after Henrietta Lacks' death, mounting evidence suggested that HeLa cells contaminated and overgrew other cell lines. Cultures, supposedly of tissues such as breast canc
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S, Shifa. "In Vitro Anticancer and Cytotoxic Activity of Ethanolic Extract of Phyllanthus reticulatus Poir. Against Hela Cell Line and Vero Cell Line." Bioequivalence & Bioavailability International Journal 8, no. 1 (2024): 1–8. http://dx.doi.org/10.23880/beba-16000223.

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The present study was designed to investigate the anticancer activity of Phyllanthus reticulatus Poir. against HeLa cell line and to predict the therapeutic potential by investigating the cytotoxicity of the extract against Vero cell line and determining the selectivity index (SI). Phytochemical screening of the ethanolic extract of Phyllanthus reticulatus Poir. was employed by using standard methods. Anticancer and cytotoxic activities were investigated from Centre for Advanced Research in Science using their commercial services. MTT assay was employed for the evaluation of the activities. Th
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Dabous, Emad, Adel, A. Guirgis, and Hany Khalil. "Studying the Role of miR-141 in Supporting Cervical Cancer Cell Proliferation." Scholars International Journal of Biochemistry 6, no. 10 (2023): 122–28. http://dx.doi.org/10.36348/sijb.2023.v06i10.001.

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MicroRNAs (miRNAs) are small noncoding RNA, approximately 18-23 nucleotides that can post-transcriptionally regulate the expression of complementary mRNAs. MiRNAs have been found to play a critical role in a broad spectrum of biological processes, such as developmental timing, cell death, cell proliferation, hematopoiesis, and nervous system patterning. Here, we aimed to investigate the possible upregulation of miR-141 in cervical cancer cells and to confirm the influential role of miR-141 in cervical cancer cell proliferation. The level of miR-141 in HeLa cells has been assessed using quantit
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Mendoza-Almanza, Gretel, Leticia Rocha-Zavaleta, Cecilia Aguilar-Zacarías, Jorge Ayala-Luján, and Jorge Olmos. "Cry1A Proteins are Cytotoxic to HeLa but not to SiHa Cervical Cancer Cells." Current Pharmaceutical Biotechnology 20, no. 12 (2019): 1018–27. http://dx.doi.org/10.2174/1389201020666190802114739.

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Background: Bacillus thuringiensis toxins are effective against multiple biological targets such as insects, nematodes, mites, protozoa, and importantly, human cancer cells. One of the main mechanisms by which Cry toxins to trigger cell death is the specific recognition of cadherin-like membrane cell receptors. Objective: This work aimed to assess the cytotoxicity of the Cry1Ab and Cry1Ac toxins from Bacillus thuringiensis in HeLa, cervical cancer cell line, as well as their antitumor activity in mouse models. Methods: We analyzed several biological targets of Cry1Ab and Cry1Ac including eryth
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Dissertations / Theses on the topic "HeLa cancer Cell"

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Flynn, Patrick G. "Activation of Non-Muscle Myosin IIB Helps Mediate TNF-Alpha Cell Death Signaling." Scholarly Repository, 2010. http://scholarlyrepository.miami.edu/oa_dissertations/369.

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TNF-alpha can stimulate a variety of kinases with the ability to activate non-muscle myosin II. As a result, increases in actin filament formation and actomyosin contractility (AMC) have been reported in response to TNF-alpha. These events are thought to play an important role in mediating TNF-alpha induced apoptosis but how they do so is unclear. In this study we prevented non-muscle myosin II activation in response to TNF-alpha by treating cells with the myosin light chain kinase (MLCK) inhibitor ML-7 or through isoform specific siRNA knockdown of myosin IIA and IIB. We found that treatme
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Tabbaa, Mahmmoud M. "Pyrithione Zinc effect on Cancer Cell Proliferation and Viability." Ohio University Art and Sciences Honors Theses / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1509614945218889.

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Robeson, Kalen Z. "Development of a Fast and Accurate Mutation Assay in Human Cell Lines." Ohio University Honors Tutorial College / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ouhonors149270391894463.

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Wortmann, Andreas. "In vitro and in vivo examination of the cell surface glycoprotein CDCP1." Thesis, Queensland University of Technology, 2010. https://eprints.qut.edu.au/40975/1/Andreas_Wortmann_Thesis.pdf.

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A number of reports have demonstrated the importance of the CUB domaincontaining protein 1 (CDCP1) in facilitating cancer progression in animal models and the potential of this protein as a prognostic marker in several malignancies. CDCP1 facilitates metastasis formation in animal models by negatively regulating anoikis, a type of apoptosis triggered by the loss of attachment signalling from cell-cell contacts or cell-extra cellular matrix (ECM) contacts. Due to the important role CDCP1 plays in cancer progression in model systems, it is considered a potential drug target to prevent the metast
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Viglianti, L. "THE HETEROARYLETHENES: SYNTHESIS, ELECTROCHEMISTRY AND INVESTIGATION ON THE AGGREGATION-INDUCED EMISSION OF A PROMISING CLASS OF MOLECULES WITH LUMINESCENT PROPERTIES." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/338784.

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The present research has been aimed on the synthesis and to the electrochemical and photophysical investigation of the HeteroArylEthene class constituted by the DiThienylEthene DTE, TriThienylEthene TrTE, TetraThienylEthene TTE, DiFurylEthene DFE, TriFurylEthene TrFE and TetraFurylEthene TFE. The study includes as a benchmark the analogous phenyl-based series which was already well known concerning the synthesis the photophysical properties and the applications. A very limited knowledge was so far available concerning the heteroaryl-based ethenes. Among the investigated systems, TFE and TrTE
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Lewis, Tyler E. "Investigation of Parameters Affecting the Nanoinjection of HeLa 229 Cancer Cells." BYU ScholarsArchive, 2015. https://scholarsarchive.byu.edu/etd/5526.

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The ability to deliver sequences of DNA and other molecular loads across the membrane of a cell and into its nucleus is an area of interest in the medical community. One of its many applications is that of gene therapy. In contrast to other forms of treatment, gene therapy seeks to treat diseases at the cellular level. The success of these treatments depends on the technologies for cell transfection that are available. Physical methods are sometimes able to overcome poor efficiencies of chemical methods and the safety concerns of viral methods, but are usually impractical due to the limited nu
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Hayes, Mark Thomas. "Investigation of the mechanisms of the genotoxicity and cytotoxicity of selected anticancer agents in human cells." Thesis, Queensland University of Technology, 1999.

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Feni, Lucia [Verfasser], Ines [Gutachter] Neundorf, and Norbert [Gutachter] Sewald. "Improving cargo delivery in cancer therapy with the help of cell-penetrating peptides / Lucia Feni ; Gutachter: Ines Neundorf, Norbert Sewald." Köln : Universitäts- und Stadtbibliothek Köln, 2019. http://d-nb.info/1191365670/34.

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Castro, Arce Johanna de. "RAR beta trans-repression of AP-1 transcription factor in HeLa cervical cancer cells consequences on transcription of viral and cellular AP-1 controlled genes /." [S.l. : s.n.], 2003. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB10806332.

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Ryan, Joseph Anthony. "Quantification via Inductively-Coupled Plasma Optical Emission Spectroscopy (ICP-OES) of the Cellular Internalization and Nuclear Localization of Gold Nanoparticles Passivated with BSA-SV40 Large T NLS Conjugates after Incubation with Human Cervical Cancer (HeLa) Cells." NCSU, 2009. http://www.lib.ncsu.edu/theses/available/etd-06132009-145408/.

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Rhodamine-labeled, cysteine-modified SV40 large T NLS peptide sequences were conjugated in varying amounts (~ 3 to 15 molar ratio) with bovine serum albuin (BSA) via the heterobifunctional linker succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC). These conjugates were then used to passivate nanomolar aliquots of citrate-coated gold nanoparticles of varying diameter (5, 10, 15, and 20 nm), and the stability of these nanoparticle complexes were evaluated with respect to: 1) amount of large T-BSA per nanoparticle (found to be stable under the following BSA:nanoparticle ratios: 5
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Books on the topic "HeLa cancer Cell"

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Skloot, Rebecca. The immortal life of Henrietta Lacks. Broadway Paperbacks, 2011.

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Skloot, Rebecca. The Immortal Life of Henrietta Lacks. Crown Publishers, 2009.

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Skloot, Rebecca. The immortal life of Henrietta Lacks. Crown Publishers, 2009.

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Skloot, Rebecca. The immortal life of Henrietta Lacks. Large Print Press/Gale Cengage Learning, 2011.

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Skloot, Rebecca. The immortal life of Henriette Lacks. Thorndike Press, 2010.

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Skloot, Rebecca. The Immortal life of Henrietta Lacks. Crown Publishers, 2010.

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Skloot, Rebecca. The immortal life of Henriette Lacks. Thorndike Press, 2010.

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Skloot, Rebecca. The immortal life of Henrietta Lacks. Broadway Paperbacks, 2011.

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Ackerman, S. J. Modern diagnostics help detect cancer early. Dept. of Health and Human Services, Public Health Service, Food and Drug Administration, Office of Public Affairs, 1991.

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1936-, Melchers F., and Potter Michael, eds. Mechanisms of B cell neoplasia 1998: Proceedings of the workshop held at the Basel Institute for Immunology, 4th-6th October 1998. Springer, 1999.

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Book chapters on the topic "HeLa cancer Cell"

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Ganeson, Suhassni, Muhammad Mahadi bin Abdul Jamil, and Radzi bin Ambar. "Breadfruit Peel Extract Impact on HeLa Cancer Cell Viability and Proliferation." In 10th International Conference on Robotics, Vision, Signal Processing and Power Applications. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6447-1_11.

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Shaik, Ilahi, A. Shameem, and P. Sasi Bhushana Rao. "Anti-cancer Activity of Selected Seaweeds Against HeLa, K-562 and MDA-MB Cell Lines." In SpringerBriefs in Applied Sciences and Technology. Springer Singapore, 2014. http://dx.doi.org/10.1007/978-981-287-050-6_4.

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Kamala Priya, M. R., and Priya R. Iyer. "Apoptotic Activity in Cervical Cancer HeLa Cell Lines Treated with Chitosan Nanoconjugated Drug Doxorubicin – as Nanocarrier for Drug Delivery." In Proceedings of the International Conference on Nanomedicine (ICON-2019). Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-25135-2_5.

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Raja Nandhini, R., H. Joy Prabu, Ebenezer Thaninayagam, R. R. Gopi, I. Johnson, and Arockiasamy Felix Sahayaraj. "Green Synthesis of Silver/Iron(Ag/Fe) and Copper/Iron(Cu/Fe) Nanoparticles for Cytotoxic Investigation on Henrietta Lacks(HeLa) Cancer Cell." In Springer Proceedings in Materials. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-5567-1_7.

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Arvas, Hayati, and Zuhat Urakci. "Gene Therapy in Oncology." In Gene Therapy. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053358824.5.

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Gene therapy refers to any method aimed at treating or alleviating a disease by genetically modifying a patien’s cells. Gene therapy for cancer is carried out by the integration of a genetic substance in a host cell by means of viral or non-viral vectors. Delivery of therapeutic nucleic acids such as genes, oligonucleotides, microRNAs (miRNA) or small combatant RNAs (siRNA) to cancer cells allows fighting cancer by inactivating oncogenes or reestablishing the production of cancer suppressor genes. Cancer remains a prevalent cause of death worldwide because of high recurrence rates after tradit
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Brix, Nikko, and Kirsten Lauber. "Immune Checkpoint Inhibition and Radiotherapy in Head and Neck Squamous Cell Carcinoma: Synergisms and Resistance Mechanisms." In Critical Issues in Head and Neck Oncology. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-23175-9_2.

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AbstractImmune checkpoint inhibition has emerged as an integral part of the standard-of-care for head and neck squamous cell carcinoma (HNSCC) in recurrent and/or metastatic stages. Clinical responses are impressive but remain limited to a minority of patients. Primary resistance of never-responders is considered to derive from host- and tumor-specific characteristics, the latter comprising tumor immune checkpoint activity, immune contexture, tumor mutational burden, neo-antigen load, and others. Secondary resistance of initially responding patients in addition, appears to be driven predominan
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Lu, Yilu, and Yongxin Ma. "Identification of piRNAs in HeLa Cells by Massive Parallel Sequencing." In Next Generation Sequencing in Cancer Research. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7645-0_11.

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Ozgokce, Mesut. "Interventional Radiological Treatments in Lung Cancer." In The Radiology of Cancer. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359364.33.

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Lung cancer (LC) is the leading cause of cancer-related deaths globally, with about 1.76 million deaths in 2018. Smoking is the main risk factor, along with genetic predisposition and asbestos exposure. Primary LC starts in the lung tissue, while secondary LC spreads from other body parts to the lungs. LC is often classified into small cell and non-small cell types, which affects treatment plans. For non-small cell LC, surgical removal is the first option. Advanced cases might be treated with chemotherapy, radiotherapy, or combinations, but complete remission is rare. Minimally invasive treatm
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Bilgic, Erdi. "The Future Role of Nanoparticles in Radiation Therapy." In The Latest Innovative Approaches in Radiation Therapy. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359425.7.

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Radiation therapy, a widely used method in cancer treatment, employs high-energy radiation to destroy cancer cells or inhibit their growth. However, traditional radiation therapy has some limitations, particularly the potential to damage healthy tissues and the issue of tumor cells developing resistance to radiation. At this point, nanoparticles emerge as a significant innovation and hold great potential in providing targeted treatment in cancer research. According to recent studies, nanoparticles can enhance the effectiveness of therapy by making tumor cells more sensitive to radiation (radio
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Montoro, Alegría, Elena Obrador, Dhruti Mistry, et al. "Radioprotectors, Radiomitigators, and Radiosensitizers." In Radiobiology Textbook. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-18810-7_11.

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AbstractThis chapter gives an overview of molecules and mechanisms able to intervene with the biological effects of ionizing radiation (IR), either related to their clinical use in radiotherapy or in the field of radiation protection in case of an accidental exposure to radiation and/or nuclear emergencies. According to the National Cancer Institute, “radiomodifiers” can be classified into (a) radioprotectors (protect molecules and tissues from direct and indirect damage induced by IR) or (b) radiomitigators (reduce and help to repair damage), depending on whether they are administered pre- or
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Conference papers on the topic "HeLa cancer Cell"

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Sarkar, Sayoni, Rohit Srivastava, and Ajit R. Kulkarni. "Defect-mediated band engineering of PEG-coated CeO2 nanostructures for amplified non-invasive photothermal treatment of cervical cancer." In Frontiers in Optics. Optica Publishing Group, 2024. https://doi.org/10.1364/fio.2024.jw5a.15.

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We demonstrate VO•-driven photothermal response of PEG-CeO2 nanostructures for cervical cancer theranostics. Under laser irradiation, an unprecedented 86.8% reduction in HeLa cells within 48 hours is achieved, with no adverse effects on adjacent healthy cells.
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Das, Dr Debashree. "A Fluorescent Heterobimetallic IrIII-PdII Complex (HBMC) Selectively Images Cancer Cells." In 8th World Conference on Chemistry and Chemical Engineering and 8th World Conference on Advanced Materials, Nanoscience and Nanotechnology. Eurasia Conferences, 2025. https://doi.org/10.62422/978-81-981865-7-7-018.

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Early detection and treatment of cancer cell is the only way to eradicate cancer in patients and this can be efficiently achieved via fluorescence imaging technique. Henceforth, we present a fluorescent heterobimetallic complex (HBMC) of Ir(III)/Pd(II) which selectively images the nucleus of the cancer cells over normal cells at a very low concentration (12 μM), established by confocal laser scanning microscopy. HBMC has a unique property by virtue of which it is selectively taken up by cancer cells (HeLa) and hence allows selective imaging of cancer cells over normal cells (HaCat). However, t
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Keta, Otilija, Jelena Bošković, Vladana Petković, et al. "Synthesis and cytotoxic activity of selected dual COX-2 and 5-LOX inhibitors in HeLa and MIA PaCa-2 human cancer cell lines." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.503k.

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Among novel cancer chemotherapy approaches, the use of cyclooxygenases (COXs) and lipoxygenases (LOXs) inhibitors represents a promising mean for cancer treatment showing lesser toxicity comparing to the currently used cytotoxic drugs. This study detailed the synthesis of three novel compounds: 1ME, BHTK-AA, and IBU-Ac, each with the capability to concurrently inhibit both COX-2 and 5-LOX. Subsequently, we assessed their effectiveness in inhibiting the proliferation of HeLa cervical and MIA PaCa-2 pancreatic cancer cells. The IC50 values for both examined cell lines were approximately 40 μM, i
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Khalilia, Walid, and Gül Özcan. "Gamma Radiation Induces Apoptosis by Over Expression of PERP Effector of p53-dependent Cell Death in HeLa Cells." In The 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response. MDPI, 2021. http://dx.doi.org/10.3390/iecc2021-09222.

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Dalimunthe, Aminah, Poppy Anjelisa Zaitun Hasibuan, and Denny Satria. "Cell Cycle Arrest Activity of Alkaloid Fraction of Litsea cubeba Lour. Heartwoods Towards HeLa Cancer Cell." In Bromo Conference, Symposium on Natural Products and Biodiversity. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0008359401740177.

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Lindstrom, Zachary K., Steven J. Brewer, Melanie A. Easter, Brian D. Jensen, and Sandra H. Burnett. "Injections of Propidium Iodide Into HeLa Culture Cells Using a Nanoinjection Lance Array." In ASME 2013 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/detc2013-13281.

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Nanoinjection lance arrays have been used to inject propidium iodide, a dye, into living cells. The lance arrays consist of approximately four million needle-like structures on a 2 × 2 cm silicon chip, fabricated using standard methods for silicon wafers. A culture of HeLa cancer cells, commonly used in genetic research, has been employed for testing the nanoinjection process. Propidium iodide at several concentrations has been used as the dye for cell injection. The dye binds to nucleic acids after injection, and does not fluoresce when not bound, allowing accurate flow cytometry measurement
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Zhang, Ganggui, Ruirui Ji, and Meng Zhao. "Fractional order transcriptional regulation model for Hela cell BPI gene of cervical cancer." In 2021 China Automation Congress (CAC). IEEE, 2021. http://dx.doi.org/10.1109/cac53003.2021.9728536.

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Čolović, Mirjana B., Lela B. Korićanac, Jelena J. Žakula, Nada Savić, Tatjana Parac-Vogt, and Danijela Z. Krstić. "The influence of Fe(III) incorporation on anti-cancer potential of a Wells- Dawson nanocluster." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.419c.

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The objective of this study was to evaluate in vitro the antitumor properties of Fe(III)-substituted monolacunary Wells-Dawson polyoxotungstate, K7[FeIII(α2-P2W17O61)(H2O)] (FeWD) using cervical carcinoma HeLa cells as a model system. HeLa cells were exposed in vitro to FeWD within the concentration range from 0.001 to 1 mM, for 24, 48, and 72 hours. The studied Fe(III)- substituted polyoxotungstate affected HeLa cell viability in a concentration- and time-dependent manner. The obtained IC50 values (μM), as an indicator of the cytotoxic potential of FeWD, were: 16.64 ± 0.49, 10.75 ± 0.97, and
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Sun, Chao, Viktor Chesnokov, and Keiichi Itakura. "Abstract 2495: Glucosamine enhances TRAIL-induces apoptosis in DU145 and Hela cancer cell lines." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-2495.

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Sun, Chao, Viktor Chesnokov, and Keiichi Itakura. "Abstract 2495: Glucosamine enhances TRAIL-induces apoptosis in DU145 and Hela cancer cell lines." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-2495.

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Reports on the topic "HeLa cancer Cell"

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Venedicto, Melissa, and Cheng-Yu Lai. Facilitated Release of Doxorubicin from Biodegradable Mesoporous Silica Nanoparticles. Florida International University, 2021. http://dx.doi.org/10.25148/mmeurs.009774.

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Cervical cancer is one of the most common causes of cancer death for women in the United States. The current treatment with chemotherapy drugs has significant side effects and may cause harm to healthy cells rather than cancer cells. In order to combat the potential side effects, nanoparticles composed of mesoporous silica were created to house the chemotherapy drug doxorubicin (DOX). The silica network contains the drug, and a pH study was conducted to determine the conditions for the nanoparticle to disperse the drug. The introduction of disulfide bonds within the nanoparticle created a fram
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99mTc SPECT-CT, Consensus QIBA Profile. Chair Yuni Dewaraja and Robert Miyaoka. Radiological Society of North America (RSNA)/Quantitative Imaging Biomarkers Alliance (QIBA), 2019. https://doi.org/10.1148/qiba/20191021.

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The quantification of 99mTc labeled biomarkers can add unique value in many different settings, ranging from clinical trials of investigation new drugs to the treatment of individual patients with marketed therapeutics. For example, goals of precision medicine include using companion radiopharmaceutical diagnostics as just-in-time, predictive biomarkers for selecting patients to receive targeted treatments, customizing doses of internally administered radiotherapeutics, and assessing responses to treatment. This Profile describes quantitative outcome measures that represent proxies of target c
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Incidence of Lung Cancer Types. National Center for Chronic Disease Prevention and Health Promotion (U.S.). Division of Cancer Prevention and Control., 2024. https://doi.org/10.15620/cdc/174572.

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More lung cancers, including small cell carcinomas, adenocarcinomas, and squamous cell carcinomas, are being found at an early stage when they are more treatable. Screening can help find lung cancers of all types before they start spreading. Lung cancer begins in the airways of the lungs. These include the bronchi (the tubes leading to the lungs), the bronchioles (tiny branches of air tubes in the lungs), and the alveoli (the tiny air sacs at the end of the bronchioles). Types of lung cancer are named after the cells found in the cancer. Doctors use special tests to determine what type of cell
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