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Journal articles on the topic 'Helicobacter pylori etiology'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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1

Alempijevic, Tamara, Miodrag Krstic, Vesna Antonic, and Slobodan Krstic. "Frequency of Helicobacter pylori infection in patients with liver cirrhosis." Srpski arhiv za celokupno lekarstvo 135, no. 9-10 (2007): 536–40. http://dx.doi.org/10.2298/sarh0710536a.

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Introduction Ulcer disease occurrence is increased among patients with liver cirrhosis. It is widely accepted that Helicobacter pylori infection is important in etiology of ulcer disease. The role of Helicobacter pylori infection in pathogenesis of ulcer disease in patients with liver cirrhosis has not been satisfactorily explored yet. Objective The aim of this study was to determine frequencies of Helicobacter pylori infection in patients with liver cirrhosis in relation to the etiology of cirrhosis, clinical stage and concomitant ulcer disease. Method We studied 50 patients with liver cirrho

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Miljkovic-Selimovic, Biljana, Branislava Kocic, and Tatjana Babic. "Campylobacter and helicobacter in the etiology of gastrointestinal diseases." Archives of Biological Sciences 64, no. 4 (2012): 1389–404. http://dx.doi.org/10.2298/abs1204389s.

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The order Campylobacterales comprises two genera: Campylobacter and Helicobacter, with a widespread distribution in both humans and animals. They are Gram-negative, spiral, helical and microaerophilic bacteria, with an optimal growth temperature of 37?C for H. pylori and 42?C for C. jejuni strains. While Helicobacter pylori are restricted to humans, other helicobacter species can be found in different mammals and occasionally in humans. Several Campylobacter species are recognized as human pathogens, while distinct species are pathogenic only occasionally, in children, the elderly and immunoco

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Herszényi, László, Márk Juhász, Emese Mihály, and Zsolt Tulassay. "A fekélybetegség és a stressz." Orvosi Hetilap 156, no. 35 (2015): 1426–29. http://dx.doi.org/10.1556/650.2015.30249.

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The discovery that Helicobacter pylori infection is the major cause of peptic ulcer disease revolutionised our views on the etiology and treatment of the disease. This discovery has tempted many experts to conclude that psychological factors and, specifically, stress are unimportant. However, Helicobacter pylori infection alone does not explain fully the incidence and prevalence of peptic ulcer disease. It has been demonstrated that stress can cause peptic ulcer disease even in the absence of Helicobacter pylori infection, supporting a multicausal model of peptic ulcer etiology. Psychological

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Urazova, R. Z. "Treatment of inflammatory periodontal diseases in children infected with Helicobacter pylori." Kazan medical journal 82, no. 3 (2001): 208–9. http://dx.doi.org/10.17816/kazmj72140.

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Microorganisms, including Helicobacter pylori, play an important role in the etiology of inflammatory periodontal diseases. The aim of our study was to study the effectiveness of topical use of metronidazole on the mucous membranes of the oral cavity in combination with antihelicobacter therapy for Helicobacter pylori infection in childhood.

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KHADEMI, BIJAN, Negar Azar Pira, Mohammad Javad Ashraf, and Abdul Hameed Chohedri. "HELICOBACTER PYLORI IN NASAL POLYPOSIS." Professional Medical Journal 19, no. 04 (2012): 455–61. http://dx.doi.org/10.29309/tpmj/2012.19.04.2256.

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Background: Nasal polyposis is an inflammatory condition of unknown etiology. Recently concern regarding GER orHelicobacter pylori as a possible pathologic cause of nasal polyps has been increasing. The present study was planned to investigate thepresence of Helicobacter Pylor in Nassal polyps by PCR , rapid Urease test and serology. Design: Case control study. Setting: ENT ward ofShiraz, Khalilli Hospital, Iran. Period: April 2006 to March 2008. Materials and Methods: 37 patients with nasal polyps who had undergonenasal endoscopic sinus surgery and 38 control subjects who had undergone septop

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Harahap, Rini Syahrani, Delyuzar, and Jessy Chrestella. "The Presence of Helicobacter pylori in cases of Chronic Tonsillitis in Medan." Sumatera Medical Journal 3, no. 1 (2020): 1–6. http://dx.doi.org/10.32734/sumej.v3i1.2044.

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Background: Helicobacter pylori is a well known pathogen which is recognized as the most frequent infection of individuals. Helicobacter pylori plays important role in the etiology og gastritis, gastric and duodenal ulcers. We investigated the presence of Helicobacter pylori as an extragastric reservoir in the tonsilectomy specimens. Aim: To determine the presence of Helicobacter pylori in cases of chronic tonsillitis in tonsilectomy specimens. Methods: This is a descriptive study with cross sectional which the sample will be obtained using consecutive sampling method. We collect 4

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Subedi, Ram Chandra, Binit Upadhaya Regmi, Bishnu Deep Pathak, et al. "Prevalence of Helicobacter pylori infection in dyspeptic patients presenting to a tertiary care center of a developing country: a cross-sectional study." F1000Research 12 (September 25, 2023): 1195. http://dx.doi.org/10.12688/f1000research.137429.1.

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Background: Among the various causes for dyspepsia in patients presenting to the gastroenterology department, Helicobacter pylori is the most common etiological agents. Here, we explore the prevalence of Helicobacter pylori infection, particularly, in dyspeptic patients and different endoscopic findings in such patients. Methods: We conducted a simple observational study in the gastroenterology department of a tertiary care center of Nepal. The Helicobacter pylori was detected using rapid urease test and endoscopic findings were collected from gastroduodenoscopy unit. The obtained data was ana

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Ghelmici, T., Iu Lupasco, V.-T. Dumbrava, and Gh Harea. "OXIDATIVE STRESS IN PATIENTS WITH CHRONIC VIRAL HEPATITIS C WITH DUODENAL ZONE ALTERATION OF HELICOBACTER PYLORI ETIOLOGY." Biological Markers in Fundamental and Clinical Medicine (collection of abstracts) 3, no. 1 (2019): 40–42. http://dx.doi.org/10.29256/v.03.01.2019.escbm24.

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9

Hardikar, Winita, Colin Feekery, Arnold Smith, Frank Oberklaid, and Keith Grimwood. "Helicobacter pylori and Recurrent Abdominal Pain in Children." Journal of Pediatric Gastroenterology and Nutrition 22, no. 2 (1996): 148–52. http://dx.doi.org/10.1002/j.1536-4801.1996.tb00063.x.

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SummaryRecurrent abdominal pain is one of the most common presentations to pediatricians; yet an organic etiology can be found in only 10% of cases. Because infection with Helicobacter pylori in adults and children results in gastritis, a causative role for the organism has been postulated. To investigate this theory, we conducted a prospective case‐control study in children with recurrent abdominal pain using serum H. pylori IgG antibodies measured by an enzyme immunoabsorbent assay. Age, sex, ethnicity, and socioeconomic status were adjusted in the statistical model. Five subjects (5.1%) and

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Zelickson, Marc S., Cathy M. Bronder, Brent L. Johnson, et al. "Helicobacter Pylori Is Not the Predominant Etiology for Peptic Ulcers Requiring Operation." American Surgeon 77, no. 8 (2011): 1054–60. http://dx.doi.org/10.1177/000313481107700827.

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As the number of patients requiring operation for peptic ulcer disease (PUD) declines, presumed contemporary ulcer etiology has largely been derived from medically treated patients not subjected to surgery. The purpose of this study was to examine the specific causes of PUD in patients requiring surgery. Our Acute Care Surgical Service registry was reviewed for patients operated on for complications of PUD from 2004 to 2009. Emphasis was placed on individual etiologic factors for PUD. There were 128 patients (52% male, 81% white) who underwent emergency operation including: simple patch closur

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Min Dong, Simon Xin. "Painting a Complete Picture of the Pathogenesis of Peptic Ulcers." Journal of Mental Health & Clinical Psychology 6, no. 3 (2022): 32–43. http://dx.doi.org/10.29245/2578-2959/2022/3.1261.

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Peptic ulcers, including duodenal and gastric ulcers, were currently considered an infectious disease caused by Helicobacter pylori. However, this etiology cannot explain the major characteristics and observations/phenomena of the disease. To address the challenge, a Complex Causal Relationship with its accompanying methodologies was applied to analyze the existing data. Peptic ulcers were identified as a psychosomatic disease triggered by psychological stress, whereas Helicobacter pylori plays a secondary role in the late phase of peptic ulceration. This etiology addresses all the characteris

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Kazantseva, E. P., A. M. Frolov, M. A. Frolov, A. V. Volkova, and A. Fadlih. "The role of systemic diseases in the etiology of chronic blepharitis." POINT OF VIEW. EAST – WEST, no. 2 (May 12, 2023): 62–65. http://dx.doi.org/10.25276/2410-1257-2023-2-62-65.

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Blepharitis is one of the most common eye diseases. Chronic blepharitis is a multifactorial disease of inflammatory, hormonal and infectious nature. In particular, chronic blepharitis is associated with helicobacter pylori infection, skin disorders (psoriasis, atopic and seborrheic dermatitis, rosacea, etc.), endocrine pathology (hypothyroidism, prostatic hypertrophy, osteoporosis), dyslipidemia and other topical (chalazion) and systemic inflammatory diseases. It is assumed that even some cardiovascular conditions (e.g. carotid artery disease) due to reduced blood supply to eyelids can cause m

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Harper, Claudia M. G., Charles A. Dangler, Shilu Xu, et al. "Isolation and Characterization of a Helicobacter sp. from the Gastric Mucosa of Dolphins, Lagenorhynchus acutusand Delphinus delphis." Applied and Environmental Microbiology 66, no. 11 (2000): 4751–57. http://dx.doi.org/10.1128/aem.66.11.4751-4757.2000.

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ABSTRACT Gastric ulcerations in dolphins have been reported for decades. Some of these lesions were associated with parasitic infections. However, cases of nonparasitic gastric ulcers with no clearly defined etiology also have been reported in wild and captive dolphins. Considerable speculation exists as to whether dolphins haveHelicobacter-associated gastritis and peptic ulcer disease. The stomachs of seven stranded Atlantic white-sided dolphins,Lagenorhynchus acutus, and 1 common dolphin,Delphinus delphis, were assessed for the presence ofHelicobacter species. Novel Helicobacterspecies were

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Nesina, I. M., T. O. Kryuchko, O. A. Poda, L. M. Bubyr, O. Ya Tkachenko, and S. I. Lytus. "Helicobacter pylori in children: modern aspects of diagnosis and treatment in the light of the latest international recommendations." CHILD`S HEALTH 19, no. 8 (2025): 510–19. https://doi.org/10.22141/2224-0551.19.8.2024.1776.

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Despite the development of modern medical science, the problem of Helicobacter pylori and Helicobacter pylori-associated diseases has remained relevant in recent decades. Current research is focused on studying the role of Helicobacter pylori in the etiology and pathogenesis of various diseases and the search for optimal schemes of eradication therapy. The issues of diagnosis and treatment of Helicobacter pylori infection in childhood are the most controversial at the present stage. Therefore, the purpose of our work was to review and evaluate new approaches to the diagnosis and treatment of H

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Al-Sadat, Mosbeh. "Role of Helicobacter Pylori in Chronic Urticaria among Egyptian Patients with Dyspepsia: A case–control study." International Journal of Dermatology and Clinical Research 3, no. 1 (2017): 026–31. https://doi.org/10.17352/2455-8605.000023.

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<strong>Background/Objective:</strong> Chronic urticaria is one of the most frequent skin diseases and still its etiology is recognized only in a minority of cases. Some recent studies point out to infections due to Helicobacter Pylori as being of major importance in the pathogenesis of chronic urticaria. This study aimed to fi nd out the association of chronic urticaria with H. pylori.

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Do, Hoang Long, Thanh Nam Nguyen, Duc Trinh Hoang, Thi Hong Cua Trinh, Thi Huong Truc Dinh, and Chi Dung Le. "RESEARCH ON THE DETECTION OF HELICOBACTER PYLORI IN SALIVA OF GASTRITIS AND DUODENITIS PATIENTS BY REAL-TIME PCR TECHNIQUE." Tạp chí Y Dược học Cần Thơ, no. 6 (October 20, 2023): 29–34. http://dx.doi.org/10.58490/ctump.2023i6.2156.

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Background: Helicobacter pylori plays an important role in the etiology and pathogenesis of gastritis and duodenitis. There are two groups of test methods to detect Helicobacter pylori infection: invasive methods and non-invasive methods. Testing for Helicobacter pylori in saliva by real-time PCR technique belongs to group of non-invasive test methods. Objectives: To determine the detection rate of Helicobacter pylori in saliva by real-time PCR technique in gastritis and duodenitis patients and to investigate some factors related to Helicobacter pylori infection detected in saliva using real-t

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17

Živković-Perišić, Snežana. "Helicobacter pylori and gastric cancer." Hospital Pharmacology - International Multidisciplinary Journal 7, no. 3 (2020): 954–65. http://dx.doi.org/10.5937/hpimj2003954z.

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Introduction: According to GLOBOCAN estimates for 2018, gastric cancer was the fifth most common cancer and the third most common cause of death from malignant diseases in the world. Although the etiology of this cancer is multiple, Helicobacter pylori infection is strongly associated with the development of gastric cancer. Methodology: A review of professional international journals and public health publications related to the association of Helicobacter pylori infection and gastric cancer Topic: As early as 1994, the International Agency for Research on Cancer and the World Health Organizat

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Kusters, Johannes G., Arnoud H. M. van Vliet, and Ernst J. Kuipers. "Pathogenesis of Helicobacter pylori Infection." Clinical Microbiology Reviews 19, no. 3 (2006): 449–90. http://dx.doi.org/10.1128/cmr.00054-05.

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SUMMARY Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the most successful human pathogens, as over half of the world's population is colonized with this gram-negative bacterium. Unless treated, colonization usually persists lifelong. H. pylori infection represents a key factor in the etiology of various gastrointestinal diseases, ranging from chronic active gastritis without clinical symptoms to peptic ulceration, gastric adenocarcinoma, and gastric mucosa-associated lymphoid tissue lymphoma. Disease outcome is the result of the complex interplay betwe

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Radhakrishnan, S., B. Al Nakib, M. Kalaoui, and J. Patric. "Helicobacter pylori‐Associated Gastritis in Kuwait." Journal of Pediatric Gastroenterology and Nutrition 16, no. 2 (1993): 126–29. http://dx.doi.org/10.1002/j.1536-4801.1993.tb10822.x.

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SummaryInformation is limited concerning the prevalence of Helicobacter pylori infection in asymptomatic children. Since January 1989, we have endoscoped 60 children for recurrent abdominal pain or for obtaining small‐intestinal biopsy (their ages were a mean of 6.6 (range 9 months‐13 years); there were 37 boys and 23 girls. Antral biopsies were obtained from all subjects and these were studied for the presence of gastritis and stained for H. pylori using modified Gram's stain. All biopsies were cultured for H. pylori. Children endoscoped for small‐intestinal biopsy (n = 18) were used for comp

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Min Dong, Simon Xin. "The Hyperplasia and Hypertrophy of Gastrin and Parietal Cells Induced by Chronic Stress Explain the Pathogenesis of Duodenal Ulcers." Journal of Mental Health & Clinical Psychology 6, no. 3 (2022): 1–12. http://dx.doi.org/10.29245/2578-2959/2022/3.1257.

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Peptic ulcers, including duodenal and gastric ulcers, are currently studied as an infectious disease caused by Helicobacter pylori. However, this etiology cannot elucidate the major characteristics and observations/phenomena of the disease, as well as the roles of gastric acid and NSAIDs. Additionally, many patients with severe ulcer symptoms have no infection, suggesting bacterial eradication cannot prevent relapses in all ulcer patients. To address these challenges, a recently published Complex Causal Relationship with its accompanying methodologies was applied to analyze the existing data.

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Tel’nykh, Yuri V., E. Z. Abgadzhava, and M. Yu Kon’kov. "Biliary reflux-gastritis: etiology, pathogenesis and modern principles of treatment." Clinical Medicine (Russian Journal) 94, no. 6 (2016): 454–57. http://dx.doi.org/10.18821/0023-2149-2016-94-6-454-457.

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Objective. To study etiopathogenetic aspects of biliary reflux-gastritis (RG) and develop modern principles of its therapy depending on acidity of stomach contents, atrophy ofgastric mucosa, and Helicobacter pylori infection. Different pathogenetic mechanisms of RG are discussed with special reference to bile flow into the antrum as a result of duodenogastric reflux. It is shown that the use of de-nol and probiotic ProBiotic Complex for the treatment of biliary reflux-gastritis increases effectiveness of H. pylori eradicationby 18.2% and prevents the development of bowel dysbiosis.

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Jayaprakash, S., C. Suganya, and Thirumalaisami. "Evaluation of Helicobacter Pylori in Patients Undergoing Upper GI Endoscopy." International Journal of Pharmaceutical and Clinical Research 14, no. 12 (2022): 799–807. https://doi.org/10.5281/zenodo.13221128.

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<strong>Background: </strong>Helicobacter pylori (i.e. H. pylori), previously known as Campylobacter, is a gram-negative, helically shaped, microaerophilic bacterium usually found in the stomach. Its helical shape (from which the genus name, helicobacter, derives) is thought to have evolved in order to penetrate the mucosal lining of the stomach and thereby establish infection. <strong>Aim:</strong> To evaluate the prevalence of helicobacter pylori in patients undergoing upper gastrointestinal endoscopy. <strong>Material and Method: </strong>The present prospective stu

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Ray, Amitabha, Thomas F. Moore, Rajashree Pandit, Adam D. Burke, and Daniel M. Borsch. "An Overview of Selected Bacterial Infections in Cancer, Their Virulence Factors, and Some Aspects of Infection Management." Biology 12, no. 7 (2023): 963. http://dx.doi.org/10.3390/biology12070963.

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In cancer development and its clinical course, bacteria can be involved in etiology and secondary infection. Regarding etiology, various epidemiological studies have revealed that Helicobacter pylori can directly impact gastric carcinogenesis. The Helicobacter pylori-associated virulence factor cytotoxin-associated gene A perhaps plays an important role through different mechanisms such as aberrant DNA methylation, activation of nuclear factor kappa B, and modulation of the Wnt/β-catenin signaling pathway. Many other bacteria, including Salmonella and Pseudomonas, can also affect Wnt/β-catenin

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Muharemovic, Arma, Sanja Hadzic, Enes Pasic, et al. "Clinical Evaluation and Microbiological Identification of Helicobacter Pylori in Patients with Oral Ulcerations Using the Polymerase Chain Reaction (PCR) Method." Materia Socio Medica 37, no. 1 (2025): 48. https://doi.org/10.5455/msm.2025.37.48-53.

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Background: The etiology of oral ulceration is multicausal with numerous predisposing factors. Studies by various authors cite Helicobacter pylori infection as a possible cause of certain oral ulcerations. Objective: The aim of the study is to prove the presence of Helicobacter pylori in the oral cavity of patients with oral ulcerations, as well as to examine the relationship between the presence of Helicobacter pylori in the oral cavity and the development of oral ulcerations. Methods: The study included regular patients at the Department and Clinic of Oral Medicine and Periodontology, Facult

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W�ndisch, T., T. D. Kim, C. Thiede, et al. "Etiology and therapy of Helicobacter pylori -associated gastric lymphomas." Annals of Hematology 82, no. 9 (2003): 535–45. http://dx.doi.org/10.1007/s00277-003-0677-2.

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Dekhnich, Natalya N., Pavel Р. Kirsov, Inna A. Sysoeva, and Anastasiia S. Gaidaichuk. "Clinical case of autoimmune atrophic gastritis." Clinical review for general practice 5, no. 6 (2024): 6–11. http://dx.doi.org/10.47407/kr2024.5.6.00427.

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The article presents a clinical case of a 62-year-old female patient with a diagnosis of autoimmune atrophic gastritis, who has been troubled by symptoms of dyspepsia for 5 years. In October 2019, she was diagnosed non-atrophic gastritis associated with Helicobacter pylori, anti-Helicobacter pylori therapy was performed, but the symptoms of the disease continued to bother. This article presents key studies that identify autoimmune atrophic gastritis. The characteristic endoscopic signs of this disease and the current treatment tactics are described. Autoimmune gastritis is a chronic autoimmune

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Yusuf, Sulaiman, and Intan Chaharunia Mulya. "Pediatric Erosive Gastritis: A Case Report." Budapest International Research in Exact Sciences (BirEx) Journal 2, no. 2 (2020): 268–71. http://dx.doi.org/10.33258/birex.v2i2.1045.

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Dyspepsia is a common gastrointestinal disorder which needs diagnostic examination test using endoscopy. Pediatric erosive gastritis, the case presented, is one of the diagnosis confirmed after endoscopy examination test which is mostly associated with Helicobacter pylori infection. A 10-year-old boy was presented to emergency department complaining cyclic vomiting, heartburn and constipation. Further inquiry revealed that similar progressive condition was also complained one year ago prompting endoscopy examination test to find out the underlying etiology. Erosive gastritis and Gastroesophage

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Filip, Ana-Maria, Sabrina-Nicoleta Munteanu, Simona Mocan, Dragoș Huțanu, Monica Pantea, and Anca Negovan. "Helicobacter pylori and autoimmunity in atrophic gastritis - comparison of clinical, endoscopic and histopathological features." Acta Marisiensis - Seria Medica 70, no. 3 (2024): 149–56. http://dx.doi.org/10.2478/amma-2024-0028.

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Abstract Objective This study aims to investigate the clinical, endoscopic, biologic and histopathological differences between Helicobacter pylori-associated and autoimmune gastric atrophy. Methods A retrospective analysis was conducted on 95 patients diagnosed with either H. pylori-related corporal and antral atrophy (43 patients) or autoimmune corporal atrophic gastritis (52 patients). Results A significant male predisposition for H. pylori-associated atrophic changes in both the antrum and corpus regions (p=0.007, OR=3.24) was observed in comparison with autoimmune etiology of atrophy. Whil

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KHASANOV, ANVAR GINIYATOVICH, ILDAR FANUSOVICH SUFIYAROV, RADIK RADIFOVICH FAYAZOV, AZAMAT FUATOVICH BADRETDINOV, and YULIA RIYAZOVNA SAGADATOVA. "ETIOPATHOGENETIC BASES OF THE DEVELOPMENT OF PEPTIC ULCER DISEASE (LITERATURE REVIEW)." Archivarius 7, no. 6(60) (2021): 16–18. http://dx.doi.org/10.52013/2524-0935-60-6-3.

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This article provides basic information about the etiology and pathophysiological mechanisms of the development of peptic ulcer of the stomach and duodenum. A brief review of the literature is conducted, the main causes of peptic ulcer disease are considered: acid-peptic factor, infection with Helicobacter pylori, etc.

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Omran Milad, Abdulhameed. "Peptic Ulcer Disease: Etiology, Epidemiology, and the Evolving Role of Helicobacter Pylori and NSAIDs." Journal of Research in Pharmaceutical Science 11, no. 2 (2025): 01–08. https://doi.org/10.35629/2995-11020108.

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Peptic ulcer disease (PUD) is a common gastrointestinal condition characterized by a break in the lining of the stomach or duodenum, often associated with Helicobacter pylori (H. pylori) infection and nonsteroidal antiinflammatory drug (NSAID) use. Focusing on the declining prevalence of H. pylori in Western countries and the rising importance of NSAIDs as a contributing factor. Despite improved hygiene and medical interventions, PUD remains a significant health concern due to widespread NSAID use, especially among older populations. The etiology of PUD is multifactorial, involving an imbalanc

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Gaevskaya, Yeuheniya, Bihara Rasanjalee Mathotaarachchi, and Dilmi Raveena Yahathugoda. "Retrospective case study of risk factors, clinical features and laboratory parameters of peptic ulcer disease in pediatric patients." International Journal of Contemporary Pediatrics 12, no. 6 (2025): 884–89. https://doi.org/10.18203/2349-3291.ijcp20251464.

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Background: Peptic ulcer disease (PUD) is uncommon in children, yet recognizing risk factors like age, gender and acute illness is crucial. While often in the duodenum, ulcers can also occur in the stomach. Helicobacter pylori is a primary cause of childhood PUD. Complications include bleeding, perforation and penetration. Chronic disease can alter laboratory parameters. Treatment involves H. pylori eradication and sometimes surgery. Methods: This observational retrospective study analyzed electronic medical data from 74 pediatric patients with gastric and/or duodenal ulcers at Health Care Ins

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Park, Su Bee. "Etiology and Therapeutic Strategies for Refractory Peptic Ulcers: A Comprehensive Review." Korean Journal of Helicobacter and Upper Gastrointestinal Research 25, no. 1 (2025): 17–22. https://doi.org/10.7704/kjhugr.2024.0072.

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The leading causes of refractory peptic ulcers are <i>Helicobacter pylori</i> infection and nonsteroidal anti-inflammatory drugs. Additionally, insufficient treatment for the suppression of gastric acid, smoking, alcohol consumption, and concomitant diseases can hinder recovery. Treatment includes the eradication of <i>H. pylori</i>, discontinuation of the causative agent, and appropriate suppression of gastric acid. Even after improvement of symptoms, sufficient proton pump inhibitor maintenance is necessary for 8 to 12 weeks. To increase the success rate of <i>H

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Sokolova, Olga, and Michael Naumann. "Matrix Metalloproteinases in Helicobacter pylori–Associated Gastritis and Gastric Cancer." International Journal of Molecular Sciences 23, no. 3 (2022): 1883. http://dx.doi.org/10.3390/ijms23031883.

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Gastric cancer is one of the leading causes of the cancer-related mortality worldwide. The etiology of this disease is complex and involves genetic predisposition and environmental factors, including Helicobacter pylori. Infection of the stomach with H. pylori leads to gastritis and gastric atrophy, which can progress stepwise to gastric cancer. Matrix metalloproteinases (MMPs) actively participate in the pathology development. The further progression of gastric cancer seems to be less dependent on bacteria but of intra-tumor cell dynamics. Bioinformatics data confirmed an important role of th

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Eissa, Adil, and Saad Mirza. "The Relevance of Helicobacter pylori Infection to Iron Deficiency Anemia in Duhok City." Iraqi Journal of Medical Sciences 19, no. 1 (2021): 33–38. http://dx.doi.org/10.22578/ijms.19.1.5.

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Background:Helicobacter pylori (H. pylori) infection had been criticized for many deleterious effects and had been amalgamated to iron deficiency by many authors, frequently based on correlative rather than direct relationship studies and often opposed by others. Objective: To evaluate the role of H. pylori infection in the etiology of iron deficiency anemia and to study the impact of the bacterial eradication on the response to iron therapy. Methods:The current study represents an interventional prospective study and involved 52 non-pregnant females with iron deficiency anemia. All patients w

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Katoh, Hiroto, and Shumpei Ishikawa. "Lifestyles, genetics, and future perspectives on gastric cancer in east Asian populations." Journal of Human Genetics 66, no. 9 (2021): 887–99. http://dx.doi.org/10.1038/s10038-021-00960-8.

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AbstractThe prevalence of gastric cancer (GC) differs among regions worldwide, with the highest occurrence in east Asia. Thus, its etiology, with respect to ethnic background, environmental factors, and lifestyles, is also thought to differ essentially. In addition, etiology of GC is speculated to be changing due to the recent decrease in the Helicobacter pylori (H. pylori) infection in Japan. State-of-the-art somatic/germline cancer genomics has clarified the etiologies of gastric carcinogenesis. In this review article, we summarize past and present milestones in our understanding of GC achie

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Lupu, Ancuta, Ingrith Crenguta Miron, Andrei Tudor Cernomaz, et al. "Epidemiological Characteristics of Helicobacter pylori Infection in Children in Northeast Romania." Diagnostics 13, no. 3 (2023): 408. http://dx.doi.org/10.3390/diagnostics13030408.

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(1) Background: Although gastritis has been associated with multiple etiologies, in pediatrics the main etiology is idiopathic. Many studies have reported mild-to-severe gastritis Helicobacter pylori (H. pylori) as an etiological factor. We evaluated the distribution of the infection with H. pylori by age, gender and place of living; (2) Methods: A retrospective study was conducted over a period of 3 years, over a cohort of 1757 patients of both sexes, aged between 1 and 18 years, admitted to a regional gastroenterology center in Iasi, Romania, with clinical signs of gastritis which underwent

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Ghosh, Uzzal Kumar, Md Imrul Kaes, Satabdi Ghosh, Mosammat Afroza Jinnat, Chandan Kumar Saha, and Md Zulfikar Ali. "Frequency of Helicobacter Pylori Infection in Children presented with Recurrent Abdominal Pain in Northern part of Bangladesh." KYAMC Journal 14, no. 01 (2023): 04–06. http://dx.doi.org/10.3329/kyamcj.v14i01.65305.

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Background: Abdominal pain is one of the common symptoms in hospital attended children. Recurrent abdominal pain also is a challenge to diagnosis. Although the most common etiology of recurrent abdominal pain is functional, organic treatable cause exclusion is justified. Peptic ulcer disease is one of the causes of recurrent abdominal pain; whereas association of Helicobacter Pylori is not so uncommon.Objective: To find out the frequency of H Pylori infection in children presented with recurrent abdominal pain.Materials and methods: A cross sectional was study done in Khwaja Yunus Ali Medical

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Crooker, A. R., W. G. Kraft, T. L. Beard, and M. C. Myers. "The rod-to-coccoid body transformation in cultures of Helicobacter pylori." Proceedings, annual meeting, Electron Microscopy Society of America 48, no. 3 (1990): 626–27. http://dx.doi.org/10.1017/s0424820100160686.

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Helicobacter pylori is a microaerophilic, gram-negative bacterium found in the upper gastrointestinal tract of humans. There is strong evidence that H. pylori is important in the etiology of gastritis; the bacterium may also be a major predisposing cause of peptic ulceration. On the gastric mucosa, the organism exists as a spiral form with one to seven sheathed flagella at one (usually) or both poles. Short spirals were seen in the first successful culture of the organism in 1983. In 1984, Marshall and Warren reported a coccoid form in older cultures. Since that time, other workers have observ

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Band, Fatima Ahmed, Mostafa Mohammed Rashed, Mslim ALI ABD, Saif Salam Hashim, and Rawnaq Mahdi Hussein. "HELICOBACTER PYLORI: FROM DISCOVERY TO MODERN-DAY TREATMENTS." European Journal of Medical Genetics and Clinical Biology 1, no. 7 (2024): 314–30. http://dx.doi.org/10.61796/jmgcb.v1i7.796.

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Helicobacter pylori, a Gram-negative bacterium, was first identified in the early 1980s as a major cause of chronic gastritis and peptic ulcer disease. Its discovery revolutionized the understanding of gastric pathology, shifting the paradigm from a solely acid-related etiology to one involving bacterial infection. This abstract provides a comprehensive overview of H. pylori, tracing its discovery, pathogenesis, and the evolution of treatment strategies. The initial identification of H. pylori by Barry Marshall and Robin Warren marked a pivotal moment in medical history, leading to widespread

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Özcan, Cengiz, Ayşe Polat, Feza Otağ, and Kemal Görür. "Does Helicobacter pylori play a role in etiology of nasal polyposis?" Auris Nasus Larynx 36, no. 4 (2009): 427–30. http://dx.doi.org/10.1016/j.anl.2008.09.007.

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Dincă, Andreea Ligia, Lorena Elena Meliț, Simona Gurzu, Simona Mocan, Dana Valentina Ghiga, and Cristina Oana Mărginean. "Helicobacter pylori—The Bridge between Local and Systemic Inflammation in Children." Applied Sciences 13, no. 4 (2023): 2162. http://dx.doi.org/10.3390/app13042162.

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Helicobacter pylori (H. pylori)-associated inflammatory status is no longer a debatable topic in children. The aim of our study was to to compare the inflammatory status in pediatric patients with H. pylori gastritis and non-H. pylori gastritis versus control group. We performed a prospective study on 68 children with dyspeptic symptoms which were divided into 3 groups: 14 children with H. pylori gastritis (group 1), 26 children with non-H. pylori gastritis (group 2) and 28 children with no pathological findings—control group (group 3). Several laboratory parameters, histopathological and immu

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Goodman, Karen J. "Implications of Helicobacter pylori infection for stomach cancer prevention." Cadernos de Saúde Pública 13, suppl 1 (1997): S15—S25. http://dx.doi.org/10.1590/s0102-311x1997000500003.

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Accumulating evidence has implicated Helicobacter pylori, an established cause of chronic gastritis and peptic ulcer, in the etiology of gastric cancer. Control of this infection would reduce the occurrence of chronic gastritis and peptic ulcer and might substantially lower the risk of stomach cancer as well. The public health impact of this infectious agent warrants efforts to identify preventive measures. This paper reviews the evidence linking H. pylori infection to gastric cancer and evaluates the potential for control in high-risk populations. Current obstacles to H. pylori control are di

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Hamid, Zainab A. "The Possible Role of Helicobacter pylori Infection in Hashimoto’s Thyroiditis." Journal of the Faculty of Medicine Baghdad 59, no. 1 (2017): 79–82. http://dx.doi.org/10.32007/jfacmedbagdad.591171.

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Background: Autoimmune thyroiditis is one of autoimmune thyroid diseases. The cause of Hashimoto’s thyroiditis is not clearly identified; however, both genetic and environmental are suggested to play a role in pathogenesis of the disease. Helicobacter pylori (H pylori) is one of the possible causative agents.Objectives: The aim of this study is to look for the association of H. pylori infection with Hashimoto’s thyroiditis.Patients and Methods: a case-control study involved patients with Hashimoto’s thyroiditis (n=100) and control group (hyperthyroidism n=50, healthy persons n=50), the study g

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Aryani, Fransisca Theresia, Agus Firmansyah, and Abdul Latief. "Comparison of combination of probiotic and standard therapy compared to standard therapy on eradication of Helicobacter pylori infection in children." Paediatrica Indonesiana 50, no. 1 (2016): 38. http://dx.doi.org/10.14238/pi50.1.2010.38-41.

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Background Helicobacter pylori (H. pylori) infection is thought to be the etiology of chronic gastritis, peptic ulcer, and risk factor for gastric cancer. Management of H. pylori infection in children is associated with several problems such as compliance to therapy, untolerated side effects, and antibiotic resistance. Probiotic is reported to give beneficial effect in the management of H. pylori infection and there is no study yet on the effect of probiotic in eradication of H. pylori infection in Indonesian children.Objectives To study the effect of additional probiotic in the standard thera

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Tsimmerman, Ya S. "Response to article of K. I. Grigoriev et al. “Peptic ulcer disease — historical dynamics: views on etiopathogenesis and treatment”, In Experimental and Clinical Gastroenterology. 2019;161(1): 155–165. (In Russ.) DOI: 10.31146/1682–8658-ecg-161–1–155–165." Experimental and Clinical Gastroenterology, no. 9 (March 24, 2020): 85–89. http://dx.doi.org/10.31146/1682-8658-ecg-169-9-85-89.

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In this article is discussed the historical facts of the study of peptic ulcer during 190 years after its self-selection in an independent nosological form. The scientific facts and arguments refuting the leading role of Helicobacter pylori infection in its etiology and pathogenesis are given; the conclusion of the authors of this article about the inevitability of a new paradigm of peptic ulcer in the near future is supported.

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Begovic, Goran, and Redzep Selmani. "Etiological Factors in Urgent Gastroduodenal Ulcer." PRILOZI 36, no. 2 (2015): 203–10. http://dx.doi.org/10.1515/prilozi-2015-0068.

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Abstract Aim: The goal of the study is to assess the impact of the etiological and risk factors in the cases of urgent gastroduodenal ulcer. Methods: This is a prospective study which included 67 patients selected randomly, all with urgent, life-threatening complications of the gastroduodenal ulcer, treated at the University Clinic for Digestive Surgery and the University Clinic for Gastroenterohepatology. For the purpose of the study the titer of IgG antibodies to Helicobacter pylori in serum is examined, as well as the use of NSAID and aspirin. We also tested the use of nicotine and alcohol.

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Iwu, Chidozie Declan, and Chinwe Juliana Iwu-Jaja. "Gastric Cancer Epidemiology: Current Trend and Future Direction." Hygiene 3, no. 3 (2023): 256–68. http://dx.doi.org/10.3390/hygiene3030019.

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Gastric cancer (GC) is a significant global public health problem. It is the third leading cause of cancer-related mortality despite its decline in incidence since the past five decades. The incidence of GC varies between regions, and this heterogeneity is attributed to multi-factors, including infectious, environmental, and genetic traits. Most of the GC cases are linked to Helicobacter pylori (H. pylori) infection. Understanding the etiology, epidemiology, and risk factors of GC is necessary for the prevention and targeted treatment of the disease. In this study, we synthesized published stu

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Chaudhary, Minal, Madhuri Gawande, and Preethi Sharma. "Evaluation of Prevalence of Bacteria Helicobacter pylori in Potentially Malignant Disorders and Oral Squamous Cell Carcinoma." World Journal of Dentistry 6, no. 2 (2015): 82–86. http://dx.doi.org/10.5005/jp-journals-10015-1319.

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ABSTRACT Cancer is a complex disease that is variable in its presentation, development and outcome. The same heterogeneity and variability exist at the cellular and molecular level. Cancer is a multistep process during which cells undergo intense metabolic and behavioral changes, leading them to proliferate in an extreme and early way to escape supervision by the immune system and ultimately invades distant tissues to form metastases. Globally, almost 20% of cancers are related to infectious agents. Several viruses with oncogenic potential stimulate cell proliferation leading to cancer in anim

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Omarov, Nail, and Omer Gezdur. "Exploring the potential link between Helicobacter Pylori and Rosacea: A retrospective matched cohort study." Medical Science and Discovery 12, no. 6 (2025): 207–12. https://doi.org/10.36472/msd.v12i6.1292.

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Objective: Rosacea is a chronic skin disorder of unknown etiology that primarily affects the central face. This study aimed to determine the prevalence of Helicobacter pylori (H. pylori) infection in patients with rosacea and to assess whether Helicobacter testing is warranted in this population. Methods: This single-center retrospective study evaluated the prevalence of gastric H. pylori infection, confirmed via the rapid urease Campylobacter-like organism (CLO) test and the 13C-urea breath test, in patients with rosacea. Upper gastrointestinal endoscopy (UGIE) was performed in rosacea patien

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Abbas, Mohammed, Faiza A. Sharif, Shamselfalah M. Osman, et al. "Prevalence and Associated Symptoms of Helicobacter pylori Infection among Schoolchildren in Kassala State, East of Sudan." Interdisciplinary Perspectives on Infectious Diseases 2018 (2018): 1–5. http://dx.doi.org/10.1155/2018/4325752.

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This study aimed to determine the prevalence of H. pylori infections among schoolchildren and investigate the associations between H. pylori seropositivity and existence of gastrointestinal symptoms. Methods. A prospective cross-sectional study was conducted during a period from January to December 2012 at Kassala state, east of Sudan. Schoolchildren from different primary schools were enrolled in the study. Sociodemographic characteristics and gastrointestinal symptoms were recorded from each child. A rapid immunochromatographic test was performed for the detection of H. pylori IgG antibodies

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