Relevant bibliographies by topics / Hematological study

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Academic literature on the topic 'Hematological study'

Author: Grafiati
Published: 4 June 2021
Last updated: 7 February 2022

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Journal articles on the topic "Hematological study"

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K, Shivani Shenoy, Raj Shekhar, Mary Mathew, and G. Arun Kumar. "A Clinico-Hematological Study of Influenza Virus Infection." Academia Journal of Medicine 2, no. 2 (July 24, 2019): 24–27. http://dx.doi.org/10.21276/ajm.2019.2.2.8.

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Makadia, Khushbu Dalasukhbhai, and Pragnesh Shah. "A Study of Hematological Changes in Neonatal Sepsis." Annals of Pathology and Laboratory Medicine 7, no. 5 (May 28, 2020): A236–240. http://dx.doi.org/10.21276/apalm.2792.

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J., Joshi Hetal. "A Study of Different Hematological Parameters in Malaria." Journal of Medical Science And clinical Research 05, no. 05 (May 6, 2017): 21503–8. http://dx.doi.org/10.18535/jmscr/v5i5.46.

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N., Gayathri B., and Kadam Satyanarayan Rao. "Pancytopenia: A Clinico Hematological Study." Journal of Laboratory Physicians 3, no. 01 (January 2011): 015–20. http://dx.doi.org/10.4103/0974-2727.78555.

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ABSTRACT Background: Pancytopenia is a relatively common hematological entity. It is a striking feature of many serious and life-threatening illnesses, ranging from simple drug-induced bone marrow hypoplasia, megaloblastic anemia to fatal bone marrow aplasias and leukemias. The severity of pancytopenia and the underlying pathology determine the management and prognosis. Thus, identification of the correct cause will help in implementing appropriate therapy. Objectives: To study the clinical presentations in pancytopenia due to various causes; and to evaluate hematological parameters, including bone marrow aspiration. Materials and Methods: It was a prospective study, and 104 pancytopenic patients were evaluated clinically, along with hematological parameters and bone marrow aspiration in Hematology Unit, Department of Pathology, JJMMC, Davanagere, during the period of September 2005 to September 2007. Results: Among 104 cases studied, age of patients ranged from 2 to 80 years with a mean age of 41 years, and male predominance. Most of the patients presented with generalized weakness and fever. The commonest physical finding was pallor, followed by splenomegaly and hepatomegaly. Dimorphic anemia was the predominant blood picture. Bone marrow aspiration was conclusive in all cases. The commonest marrow finding was hypercellularity with megaloblastic erythropoiesis. The commonest cause for pancytopenia was megaloblastic anemia (74.04%), followed by aplastic anemia (18.26%). Conclusion: The present study concludes that detailed primary hematological investigations along with bone marrow aspiration in cytopenic patients are helpful for understanding disease process and to diagnose or to rule out the causes of cytopenia. These are also helpful in planning further investigations and management.
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Manzoor, Fahim, ManjiriN Karandikar, and RavindraC Nimbargi. "Pancytopenia: A clinico-hematological study." Medical Journal of Dr. D.Y. Patil University 7, no. 1 (2014): 25. http://dx.doi.org/10.4103/0975-2870.122763.

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Gangat, Naseema, Aneel A. Ashrani, Tanya M. Petterson, Jeffery Schmoll, and John A. Heit. "Hazard of Subsequent Hematological Cancer in Patients with Incident Venous Thromboembolism (VTE): A Population-Based Cohort Study." Blood 110, no. 11 (November 16, 2007): 2154. http://dx.doi.org/10.1182/blood.v110.11.2154.2154.

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Abstract Background: While currently-diagnosable hematological cancer is a potent VTE risk factor (RR range =12–32), whether undiagnosable hematological cancer is a risk factor is uncertain. Objective: To estimate the hazard of subsequent hematological cancer among incident VTE patients with no apparent active hematological cancer within ± 3 months of the VTE event. Methods: In a population-based cohort study, we followed Olmsted County, MN residents with incident VTE over the 27-year period, 1973–1999, and previously matched Olmsted County residents without VTE, who survived with no apparent active hematological cancer within ± 3 months of the VTE event or a routine medical visit date, respectively, forward in time through their complete medical records in the community for hematological cancer. Data were abstracted on baseline demographic and clinical characteristics, type and stage of hematological cancer, and any prior solid tumor treatments. For cases and controls, hematological cancer-free survival from the event date was estimated by the Kaplan Meier method, and the homogeneity of survival curves was examined by the log-rank test. Cox proportional hazards regression was used to adjust for covariates. Results: 1860 VTE cases (56% females) and 1890 controls (53% females) were followed for 16,497 and 15,320 person-years, respectively, conditional on surviving 3-months free of hematological cancer. 43 VTE cases and 24 controls developed hematological cancer at a median of 63.5 months (range 0.7 – 334 months). The median age for cases was 63.2 years compared to 67.8 years for the controls (p<0.001). Hematological cancer types included non-Hodgkin’s lymphoma (n=19), chronic lymphocytic leukemia (n=11), acute myeloid leukemia (n=1), multiple myeloma (n=9), myeloproliferative disorders (n=10), and myelodysplastic syndromes (n=14). Case status was not univariately associated with subsequent hematologic cancer (HR=1.42; 95% CI: 0.85, 2.39; p=0.18). After adjusting for age, also associated with cancer, case status was significantly associated with hematological cancer (HR=1.90; 95% CI: 1.13, 3.20; p=0.015). Conclusions: Incident VTE patients have nearly a two-fold increased risk of subsequent hematological cancer. We hypothesize that VTE can be the initial manifestation of an occult hematological cancer clone.
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Waghmare, Tejaswini, Daksha Prabhat, and Naveen Vairamoorthy D. "A Clinico-Hematological Study of Cases of Leucoerythroblastic Reaction." Annals of Pathology and Laboratory Medicine 6, no. 2 (February 15, 2019): A103–111. http://dx.doi.org/10.21276/apalm.2410.

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Kumar Koirala, Prakash, Bidita Khandelwal, and Forhad A. Zaman. "Study of Hematological Profile and Effect of Antitubercular Medications on the Hematological Derangements in Patients Suffering from Tuberculosis." Indian Journal of Emergency Medicine 3, no. 1 (2017): 45–50. http://dx.doi.org/10.21088/ijem.2395.311x.3117.7.

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Prasanna, N., Punyashetty Kajal B., Ananthrao Anand Shankar, and Patil Tejeshwini. "Clinico-Hematological Profile in Dengue: A Tertiary Care Institutional Study." Indian Journal of Pathology: Research and Practice 6, no. 1 (2017): 75–81. http://dx.doi.org/10.21088/ijprp.2278.148x.6117.12.

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S., Arundhathi, Sunitha S., Balumahendran K., and Rajeev Gandham. "A Case- Control Study on Hematological Profile in Thyroid Dysfunction." Indian Journal of Pathology: Research and Practice 7, no. 5 (2018): 592–94. http://dx.doi.org/10.21088/ijprp.2278.148x.7518.3.

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Dissertations / Theses on the topic "Hematological study"

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HESS, JEFFREY E. "A PILOT STUDY OF OCCUPATIONAL EXPOSURE TO 1-BROMOPROPANE LOOKING FOR NEUROLOGICAL AND HEMATOLOGICAL EFFECTS." University of Cincinnati / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1022098837.

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Karius, Tommy Verfasser], and Jörn [Akademischer Betreuer] [Walter. "Optimizing epigenetic therapies of hematological malignancies : identification of novel epigenetic biomarkers and mechanistic study of 5-aza-2'-deoxycytidine / Tommy Karius. Betreuer: Jörn Walter." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2012. http://d-nb.info/1052338844/34.

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Silva, Jandira Maciel da. "Canceres hematologicos na região sul de Minas Gerais." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309615.

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Orientador: Heleno Rodrigues Correa Filho
Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas
Made available in DSpace on 2018-08-11T19:31:13Z (GMT). No. of bitstreams: 1 Silva_JandiraMacielda_D.pdf: 4032092 bytes, checksum: baaf8a956aeb177cbfbb94ada6b0a565 (MD5) Previous issue date: 2008
Resumo: Contemporaneamente, o câncer vem sendo considerado um grave problema de saúde pública em todo o mundo, observando-se aumento na mortalidade e nas taxas de incidência. No Brasil, representa a segunda causa de mortalidade. A maioria dos estudos epidemiológicos sobre exposição ocupacional e câncer tem sido realizada nos países desenvolvidos, com características sócio-econômicas diversas daquelas observadas em países não desenvolvidos. Nos países industrializados estima-se que as exposições ocupacionais sejam responsáveis por cerca de 4% de todos os cânceres humanos. Este estudo avaliou possíveis associações entre cânceres hematológicos e exposição a cancerígenos ocupacionais em pacientes residentes na Região Sul de Minas Gerais, representada por 130 municípios e 2.167.585 habitantes. A abordagem metodológica foi a de um estudo epidemiológico observacional, do tipo caso - controle, na razão de 1:1, com base em registros públicos realizados para casos de câncer atendidos e tratados no Sistema Único de Saúde da região. Controles foram pacientes usuários dos serviços de saúde da região, não portadores de diagnósticos compatíveis com câncer. O estudo incluiu 139 casos e 160 controles não emparelhados. Coletaram-se informações sobre exposição ocupacional às substâncias químicas, com destaque, para os agrotóxicos e os solventes orgânicos. Associações positivas, com significância estatística, entre cânceres hematológicos e exposições ocupacionais foram observadas, tanto para agrotóxicos (OR=3,471; IC95%=2,009-5,998), como também, para o grupo de solventes orgânicos, lubrificantes, combustíveis e tintas (OR=2,730; IC95%=1,503-4,960). Regressão logística evidenciou associação mais forte para os agrotóxicos (OR=3,976; IC95%=2,266-6,976), diante dos solventes, combustíveis e lubrificantes (OR=2,539; IC95%=1,398-4,614) após o ajustamento para idade
Abstract: Contemporarily, the Cancer has been considered a serious problem of public health in whole world. Its standard of world-wide distribution presents important geographic variations, being observed an increase in the mortality and in the rates of incidence. In Brazil, the neoplasms represent the second more common cause of mortality. Almost the totality of the epidemiological studies searching to relate occupational exposition and cancer has been carried through in the developed countries, with diverse social and economic characteristics of those observed in countries like Brazil. In the industrialized countries it is esteemed that the occupational expositions are responsible for about 4% of all the human cancers. This study has as objective to study possible associations between hematological cancers and exposition to occupational carcinogens in resident patients in the south region of Minas Gerais, region which is composed by 130 cities and 2.167.585 inhabitants. The methodological approach is an epidemiological study of case - control type, in the rate of 1:1, based on carried through public registration for cases of cancer that entered and were treated in the Unique System of Health - SUS of the region. The study included 139 cases and 160 controls. Information had been collected on occupational and ambient exposition to chemical substances, with prominence, for the pesticides and the organic solvent. Associations between hematological cancers and exposition to occupational and ambient risks factors had been investigated, including pesticides and organic solvent. After calculating the Odds Ratio - OR of hematological cancers, with the respective intervals (IC 95%), it was concluded that the pesticides and the organic solvent can contribute to the cause of the hematological cancers
Doutorado
Saude Coletiva
Doutor em Saude Coletiva
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Costa, Renata de Oliveira. "Linfoma não Hodgkin extralinfonodal gástrico: estudo retrospectivo do Serviço de Hematologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/5/5136/tde-21062007-111521/.

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Aproximadamente 40% dos casos de Linfoma não Hodgkin (LNH) se originam fora dos linfonodos, sendo então denominados linfomas extralinfonodais. No trato gastrointestinal (TGI), o estômago é o local mais freqüentemente envolvido, representado pelo linfoma MALT e pelo linfoma difuso de grandes células B (LDGCB). No Brasil, apesar da sua freqüência e importância, existem poucos dados epidemiológicos em relação aos linfomas, especialmente no que se refere aos linfomas de origem extralinfonodal. Para avaliar as características dos linfomas primários gástricos em uma população brasileira, 60 casos foram avaliados retrospectivamente. Trinta e oito (63,3%) foram classificados como LDGCB e 22 (36,6%) como MALT. Entre os dois grupos, não houve diferenças significativas em termos de sexo, idade, sintomas dispépticos, sintomas B, presença de massa Bulky, infiltração de medula óssea, estádio, infecção por H. pylori, achados laboratoriais e endoscópicos. Foram adotados diferentes protocolos de tratamento. A taxa de remissão completa foi de 73,1% no LDGCB e de 95% no linfoma MALT. A taxa de sobrevida livre de doença em 7 anos foi de 84,8% no LDGCB e de 94,1% no linfoma MALT. A taxa de sobrevida global em 7 anos foi de 65,7% no LDGCB e de 92,9% em 5 anos no linfoma MALT. Como não conseguimos demonstrar diferenças entre os dois tipos histológicos, concluímos que o diagnóstico histológico correto é essencial para a terapêutica mais adequada.
Approximately 40% of the non-Hodgkins Lymphoma arises outside lymph node tissue, being then termed extranodal lymphoma. In the gastrointestinal tract, gastric is the commonest localization represented by MALT and diffuse large B-cell lymphoma (DLBCL). In Brazil, despite its importance and frequency there are very few epidemiological data concerning lymphomas, specially the extranodal ones. In order to study the primary gastric lymphoma features in a Brazilian population, 60 patients were retrospectively evaluated. Thirty eight cases (63.3%) were classified as DLBCL and 22 (36.6%) as MALT lymphoma. There were no significant differences between the 2 groups in terms of sex, age, gastric symptoms, B symptoms, Bulky disease, bone marrow infiltration, stage, H. pylori infection, laboratory and endoscopic findings. Different treatment methods were adopted. The complete remission rate was 73.1% for DLBCL and 95% for MALT lymphoma. The disease free survival in 7 years was 84.8 for DLBCL and 94.1% for MALT lymphoma. The 7 year overall survival (OS) rate for DLBCL was 65.7% and 5 year OS for MALT was 92.9%. Because we could not demonstrate differences between the two histological groups, we conclude that the correct histological diagnosis is essential for choosing the best therapeutic approach.
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Massawe, Siriel Nanzia. "Anaemia in women of reproductive age in Tanzania : A study in Dar es Salaam." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5308-2/.

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Gaspar, Helena Alves. "Veterinary Medicine in Exotic and Wild Species: A retrospective study of hematological parameters in Psittacus erithacus." Master's thesis, 2018. http://hdl.handle.net/10348/8446.

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Over the past decade, cage and aviary birds have dramatically increased in popularity as pets. African Grey parrot (Psittacus erithacus) is a species of parrot that belongs to the order Psittaciformes of the Class Aves. Grey parrots are very popular pets due to their intelligence and their ability to mimic human voices, both in tone and range of each person. According to “BirdLife International”, as of 2015 two species of Grey parrots are considered: the African Grey parrot (Psittacus erithacus) and the Timneh parrot (Psittacus timneh). The most commonly seen in clinical practice is the African Grey parrot (Psittacus erithacus). Despite bird species being approximately twice as more as mammal species, studies on the hematological parameters of healthy individuals are still scarce in avian species. Furthermore, hematological profiles are critical to the understanding of several disease processes, being particularly useful as diagnostic tools in clinical practice, since birds tend to hide clinical signs of disease. The objective of the present work is to evaluate the influence of variability factors such as age, sex, diet and sedation on the hematological parameters of healthy African Grey parrots and to compare those parameters with the published reference intervals (RI). Data from blood samples of African Grey parrot (Psittacus erithacus) healthy individuals was collected in Zoològic Veterinaris (Barcelona). Blood samples (n=459) were taken during March 2009 to July 2017 from animals (n=239) that were examined in first consultations or check-ups. The animals had no alterations in the clinical examination and no alterations were found in the serum biochemistry analysis, coprology testing or other tests performed. Hematological testing was performed to determine hematocrit (Hct), mean hemoglobin concentration (MHC), mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), total erythrocyte count (RBC), total leukocyte count (WBC), and differential leukogram with absolute and relative counts. All hematological testing was performed in an in-house laboratory and sampling and analysis methods remained constant throughout the whole study. Animals with 0 to 4 years of age showed higher values of Hct (p<0,001), Hgb (p=0,023) and RBC (p=0,018) and lower values of MCHC (p=0,008), WBC (p=0,012) and heterophils (p<0,001) than older animals. Monocytes exhibited significant differences (p=0,035) between different age groups. Females presented higher values of hematocrit, Hgb and RBC (p<0,001) compared to males. Sedated animals showed lower values of WBC (p<0,001), heterophils (p=0,006), lymphocytes (p=0,003) and monocytes (p=0,03) but higher values of Hgb (p=0,01), MCH (p=0,025) and MCHC (p< 0,001). Additionally, part of the hemograms displayed values outside the RI, namely MCV, WBC and monocyte values. Our results suggest that age and sex influence hematological parameters in African Grey parrots. Sedation also affects these parameters, and may help to reduce the stress associated to blood collection. These results can contribute to the creation of databases that would help to establish appropriate RI for this species.
Na última década, as aves têm sido animais de companhia cada vez mais populares. O Papagaio-cinzento (Psittacus erithacus) é uma espécie de papagaio que pertence à ordem Psittaciformes e à Classe Aves. A popularidade crescente deste animal como animal de companhia deve-se, em grande parte, à sua inteligência e à sua capacidade de imitar vozes humanas, quer no timbre, quer na amplitude de voz. De acordo com a associação “BirdLife International”, e a partir de 2015, são consideradas 2 espécies de Papagaios-cinzentos: o Papagaio-cinzento-do-Congo (Psittacus erithacus) e o Papagaio-cinzento-de-Timneh (Psittacus timneh). A mais frequente em clínica é o Papagaio-cinzento-do-Congo designado por Papagaio-cinzento (Psittacus erithacus). Os parâmetros hematológicos de aves saudáveis não têm sido alvo de estudos tão aprofundados como os de mamíferos, apesar de existirem aproximadamente o dobro de espécies de aves. Os perfis hematológicos são fundamentais para a compreensão de inúmeros processos de doença, sendo particularmente úteis como ferramentas de diagnóstico na prática clínica, uma vez que as aves tendem a ocultar sinais clínicos de doença. O objectivo do presente estudo é avaliar a influência de factores de variabilidade como a idade, sexo, dieta e sedação nos parâmetros hematológicos de Papagaios-cinzentos saudáveis e comparar os valores obtidos com os valores de referência estabelecidos. Dados de amostras de sangue pertencentes a indivíduos saudáveis da espécie Papagaio-cinzento (Psittacus erithacus) foram obtidos na Zoològic Veterinaris (Barcelona). As colheitas de sangue (n=459) foram realizadas em animais (n=239) que foram submetidos a exame do estado geral em primeiras consultas ou em consultas de rotina durante o período compreendido entre março de 2009 e julho de 2017. Os indivíduos não apresentaram alterações no exame de estado geral, bem como não demonstraram alterações nos exames bioquímicos, coprológicos e outros testes realizados. Foram realizados testes hematológicos de modo a determinar o hematócrito, concentração de hemoglobina, volume corpuscular médio, hemoglobina corpuscular média, concentração de hemoglobina corpuscular média, contagem total de eritrócitos, contagem total de leucócitos, contagem diferencial de leucócitos, tanto absoluta como relativa. Todos estes exames foram efectuados no laboratório do hospital e as metodologias de colheita e análise foram mantidas constantes ao longo do estudo. Verificou-se que os animais com idades compreendidas entre 0 e 4 anos exibiam valores mais elevados de Hct (p<0,001), Hgb (p=0,023) e RBC (p=0,018), e valores mais baixos de MCHC (p=0,008), WBC (p=0,012) e heterófilos (p<0,001) quando comparados com os animais mais velhos. Os monócitos mostraram diferenças significativas (p=0,035) entre diferentes idades. Relativamente ao sexo, as fêmeas apresentaram valores mais elevados de hematócrito, Hgb e RBC (p<0,001) quando comparadas com os machos. Animais sedados tinham valores mais baixos de WBC (p<0,001), heterófilos (p=0,006), linfócitos (p=0,003) e monócitos (p=0,03), mas valores mais elevados de Hgb (p=0,01), MCH (p=0,025) e MCHC (p< 0,001). Uma porção dos hemogramas mostrou valores fora dos valores de referência, nomeadamente MCV, WBC e valores de monócitos.
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Hsieh, Ming-Hung, and 謝明宏. "Follow-Up Study Of Hematological Effects Of Exposure To Ethylene Glycol Monoethyl Ether Acetate In A Silk-Screening Factory." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/64429747487644566355.

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碩士
高雄醫學大學
職業安全衛生研究所碩士班
93
Abstract Background: Ethylene glycol ether (including ethylene glycol ether esters) are a group of solvents with medium-high boiling points and low evaporation rates. They have been widely used in coatings and in many other industries. Recently, the low molecular weight E-series glycol ethers (including ethylene glycol monomethyl ether (EGME, 2-ME), ethylene glycol monomethyl ether acetate (EGMEA, 2-MEA), ethylene glycol monoethyl ether (EGEE, 2-EE), ethylene glycol monoethyl ether acetate (EGEEA, 2-EEA), have been found to have haematological, neurological, reproductive and teratogenic toxicity. Ethylene glycol monoethyl ether acetate(EGEEA) is a solvent with broad industrial and commercial applications. It may be absorbed through gastrointestinal tract, respiratory tract and skin. Ethoxyacetic acid (EAA) the toxic metabolite of 2-EEAc, has been reported to cause encephalopathy, haematological toxicity, and infertility and teratogenesis. So far, there’s no related long-term study of exposed to ethylene glycol ethers except for haematological effect of exposed to 2-ME in copper-clad laminate manufacturer. Objective: The objective of this study is to investigate the health effects, especially haematological effect, in the 2-EEAc exposed workers in studied silk-screening factory and to follow-up the haematological effects in a previously studied silk-screening factory workers after engineering control of 2-EEAc exposure. Methods: The longitudinal study was based on the factory. To discuss workers’ haematological effects of exposed to 2-EEAc with health examination from 1998 to 2003. The silk-screening factory is in Taichung Industry Park. 40 high exposure workers (exposed group) and 47 low exposure workers (comparison group) was selected as the study population. Exposed group was from the silk-screening department, yet comparison group was from the photosensitising room, design room, product compiling room, cutting room, and administrative workers. Information of personal characteristics and working habits was obtained by using of the interview questionnaire. Result: Of the cross-sectional survey, the haemoglobin and haematocrit in the female high 2-EEAc exposure workers were significantly lower than those of female workers in the comparison group in 1998. The haemoglobin, haematocrit, and RBC count in the study population had a significant dose-response relation with air 2-EEAc levels in 1998.There’s no difference between the female high 2-EEAc exposure workers and female comparison workers with the the haemoglobin and haematocrit in 2000 and 2003. Of the longitudinal study, the trend is on the rise with the haemoglobin, haematocrit, and RBC count of the female high 2-EEAc exposure workers, yet the trend is no difference in male workers. After adjusted for age, sex, BMI, and education level, the haemoglobin, haematocrit, and RBC count of the exposed workers were much higher 1.55 g/dl、4.39 % and 0.55 106/ul, respectively, through the 3 checkup years. Discussion: Even though air-2EEAc was raised, the haematological effects of female high 2-EEAc exposure workers did improved. Thus it could be seen the recovery from haematological effect that the workers avoid directly dermal exposure of 2-EEAc but wearing rubber gloves. Still, it needs to find out the further relationship of concentration of urinary EAA, the metabolite of 2-EEAc, to affect the haematological effect.
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Hill, Q. A., R. J. Kelly, C. Patalappa, A. M. Whittle, Andy J. Scally, J. Hughes, A. J. Ashcroft, and A. Hill. "Survival of patients with hematological malignancy admitted to the intensive care unit: prognostic factors and outcome compared to unselected medical intensive care unit admissions, a parallel group study." 2012. http://hdl.handle.net/10454/6367.

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Improved survival in patients with hematological malignancy (HM) admitted to the intensive care unit (ICU) has largely been reported in uncontrolled cohorts from single academic institutions. We compared hospital mortality between 147 patients with HM and 147 general medical admissions to five non-specialist ICUs. The proportion of patients surviving to hospital discharge was significantly worse in patients with HM (27% vs. 56%; p < 0.001). Six-month and 1-year survival in patients with HM was 21% and 18%, respectively. HM, greater age, mechanical ventilation (MV) and acute physiology and chronic health evaluation (APACHE) II score were independent predictors of poor outcome. For patients with HM, culture proven infection, age, MV and inotropes were negative predictors. Disease-specific factors including hematological diagnosis, neutropenia, remission status, prior stem cell transplant, time from diagnosis to admission and degree of prior treatment were not predictive. Overall survival of patients with HM was worse than that recently reported from specialist units.
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Li, Dian-Kun, and 李典錕. "Study of Decoy Receptor 3 in Hematologic Malignancy." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/92736707427163499703.

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碩士
國立臺灣大學
臨床醫學研究所
93
Study of Decoy Receptor 3 Expression in Hematologic Malignancies Decoy receptor 3 (DcR3), a soluble decoy receptor, belongs to the tumor necrosis factor receptor superfamily. Decoy receptor 3 binds Fas ligand, LIGHT, and TL1A, and inhibits Fas ligand- and LIGHT-mediated cell apoptosis and TL1A-medaited angiostatic reaction. DcR3 is expressed in several types of malignant tumors, and is postulated to endow tumor cells to escape immune surveillance. We investigated the bone marrow DcR3 expression in patients with acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myeloid leukemia (CML), multiple myeloma (MM), and myeloid dysplastic syndrome (MDS), and also evaluated the clinical relevance of DcR3 expression in AML patients. We examined plasma DcR3 levels of bone marrow blood with enzyme-linked immunosorbent assay (ELISA) in 23 healthy bone marrow donors, 95 AML patients, 21 ALL patients, 16 CML patients, 19 MM patients, and 18 MDS patients. Bone marrows from 23 healthy marrow transplantation donors were used as normal controls. The DcR3 protein expression in malignant cells was demonstrated by immunohistochemical staining (IHC). We also examined the DcR3 mRNA expression of leukemic cells by RT-PCR and compared with β-actin expression. The DcR3 levels (mean±S.D.) were 0.42±0.35ng/ml in healthy bone marrow donors, 5.97±18.12 ng/ml in AML patients, 21.95±82.54ng/ml in ALL patients, 0.83±1.48 in CML patients, 0.19±0.31ng/ml in MM patients, 1.40±2.06ng/ml in MDS patients. The IHC showed positive staining of DcR3 in the leukemic cells from the AML patients with elevated serum level of DcR3. The DcR3 mRNA expression of leukemic cells was also correlated with the plasma DcR3 levels. We used the DcR3 level of 1.5ng/ml as cut-off level. There is no significant correlation between DcR3 levels and clinical parameters, except the age, in AML patients. 71 AML patients received induction chemotherapy. The DcR3 levels have no significant association with overall survival in these patients. 49 AML patients achieved hematologic complete remission after induction chemptherpay. The DcR3 levels have no significant association with disease free survival in these patients. We examined the DcR3 levels before and after induction chemotherapy in 7 AML patients who had hematologic complete remission. The DcR3 levels significantly decreased after induction chemotherapy. This is the first study to investigate the DcR3 expression in AML, ALL, CML, MM, and MDS. A significant portion of AML patients showed higher levels of marrow DcR3 than normal controls. In contrast, the marrow levels of DcR3 in MM patients were not increased compared with that in normal controls. The plasma DcR3 level of bone marrow blood may be a potential marker for monitoring of treatment response of AML.
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Kuan, Yuan-Peng, and 官苑芃. "The Study in Normal Healthy Body Ratio, Hematologic and Biochemical Reference Values of Mauremys reevesii." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/31852191456986104213.

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碩士
國立臺灣大學
臨床動物醫學研究所
100
The Reeve’s turtle (Mauremys reevesii) is one of the four endemic freshwater turtle species found in Taiwan. Due to overharvesting and habitat destruction, the Reeve’s turtle is now nearly extinction in Taiwan, and the only stable population is currently restricted in Kinmen island. The status of this turtle is currently listed as endangered on the IUCN Redlist and protected under the Wildlife Conservation Law as an endangered species in Taiwan, however the related conservation medicine studies of this species are still lacking. The purpose of this study is to establish the normal healthy body ratio, hematologic and biochemical reference values of the Reeve’s turtle, which can be applied on the clinical veterinary medicine and wildlife conservation. 27 clinically healthy and mature Reeve’s turtle from Kinmen were sampled in this research, which including 12 males and 15 females. The normal healthy body ratio was assessed by Jackson’s ratio and regressive equation between logarithm body weight and logarithm carapace length. In the establishment of hematological and biochemical reference values, the blood samples were collected from the same group of Reeve’s turtle in April, July, November of 2011 and February of 2012 as the representative months of the four seasons. Complete blood count was performed including hematocrit, hemoglobin concentration, red and white blood cell count and cytological differential count. Blood biochemistry items included albumin, total protein, uric acid, blood urea nitrogen (BUN), creatinine, glucose, aspartate aminotransferase (AST), alanine aminotransferase (ALT), Alkaline phosphatase (ALKP), cholesterol, triglycerides, calcium, phosphorus, creatine kinase (CK), γ-Glutamyltransferase (GGT), Lactate dehydrogenase (LDH) and electrolytes (sodium, potassium and chloride). The normal reference interval was established by the principles of the International Federation of Clinical Chemistry (IFCC). The data was further analyzed, hoping to determine whether some variables like gender and season can affect those parameters. The results showed that there were high correlations between body weight and carapace length. With increasing carapace length, the Jackson’s ratio also increases. The regressive equation between logarithm body weight and logarithm carapace length were also established, thus we can predict the normal body weight of the turtle based on its carapace length of different seasons and gender. Significant sex differences of heterophil and basophil percentage, AST, calcium, phosphorus, cholesterol, total protein and triglyceride were observed. Seasonal variations were noted in most parameters, which representing food intake and metabolic function except white blood cell count and their percentage, AST and ALT. The differences between sex and seasons were primarily associated with female reproduction stage and lower temperature in winter (wintering). The blood cell morphology and cytochemical characteristic of the Reeve’s turtle are resemble to most reptiles, thus we can differentiate these cells directly using microscope. The most abundant leukocytes are heterophils and basophils, followed by monocytes and lymphocytes, and the eosinophils are the rare one. The results of assessment of normal healthy body ratio and hematological and biochemical reference values presented in this study can be applied on clinical veterinary medicine and wildlife conservation in this species, such as wildlife casualties, quarantine and shelter. Also, these data of the Reeve’s turtle can be integrated with former researches about other freshwater turtles in Taiwan, completing the conservation medicine database of endemic freshwater turtles in Taiwan.
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Books on the topic "Hematological study"

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Hudson, Janice L. A study guide of clinical hematology: Theory and practice. Philadelphia: F.A. Davis, 1994.

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Andrew, Amos, and Smith Alastair, eds. Clinical haematology: A postgraduate exam companion. Oxford: Butterworth-Heinemann, 1997.

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Loaiciga, Francisco, and Rony Dev. Parenteral Nutrition in Cancer Patients Undergoing Chemotherapy (DRAFT). Edited by Nathan A. Gray and Thomas W. LeBlanc. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190658618.003.0023.

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The meta-analysis by McGeer investigates the benefits of parenteral nutritional support for patients with cancer undergoing chemotherapy. The study concluded that total parenteral nutrition (TPN) has a detrimental effect (decreased survival and poorer tumor response), with an increased infection risk but no significant effect on hematologic or gastrointestinal toxicity. The authors report a net harm with the use of TPN in patients undergoing chemotherapy and recommend that such interventions should be discouraged. This chapter describes the basics of the study, briefly reviews other relevant studies and information, gives a summary and discusses implications, and concludes with a relevant clinical case.
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Association, Medical Library, and Medical Economics Research Group, eds. MLA custom research study: Coagulation/hemostasis in the lab. Montvale, NJ (Five Paragon Dr., Montvale, 07645): Medical Economics Pub., 1991.

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MCQ's for the MRCP Part 1: Infectious Disease, Haematology and Chemical Pathology (MRCP Study Guides). Bailliere Tindall, 1999.

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Smith, Alastair, Drew Provan, and Andrew Amos. Clinical Haematology: A Postgraduate Exam Companion. A Hodder Arnold Publication, 1997.

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Book chapters on the topic "Hematological study"

1

Brown, L. M., D. J. Tollerud, W. A. Blattner, and R. N. Hoover. "Racial Variations in Immune Function and Hematological Parameters: Description of Study Design and Objectives." In Epidemiology and Biology of Multiple Myeloma, 43–44. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76655-8_7.

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Gagnon, Patrick J., Celine Bicquart Ord, and Carol Marquez. "Hematologic Malignancies." In Radiation Oncology Study Guide, 325–51. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-6400-6_12.

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Blaise, D., D. Olive, M. Brandely, A. M. Stoppa, R. Gabus, P. Tiberghien, M. Attal, et al. "Use of Recombinant Interleukin-2 (RU 49637) After Autologous Bone Marrow Transplantation in Patients with Hematological Disease: Phase I–II Study." In Cytokines in Hemopoiesis, Oncology, and AIDS II, 769–74. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-48715-6_97.

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Tucci, Jonathan, and Steven D. Mittelman. "Mouse Models to Study Obesity Effects on Hematologic Malignancies." In Energy Balance and Cancer, 97–116. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-16733-6_5.

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Kaipainen, Pekka, Tuomas Westermarck, Faik Atroshi, Markus Kaski, and Maati Iivanainen. "Clinical and Hematological Profiles During Valproate Treatment of Epileptic Patients with Intellectual Disability — Case Study and Mini Review." In Pharmacology and Nutritional Intervention in the Treatment of Disease. InTech, 2014. http://dx.doi.org/10.5772/57369.

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Yacoub, Amal M., Sherifa Mostafa M. Sabra, and Mona Khaled D. Al-Kourashi. "Meat Quality and Hematological Indices of Oreochromis niloticus Fish Experimentally Exposed to Escherichia coli Toxins: A Recent Study." In Recent Research Advances in Biology Vol. 11, 97–113. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/rrab/v11/2427f.

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Udristoiu, Aurelian. "Study on New Principles of Treatments in Malignant Hematological Diseases, as Acute and Chronic Lymphocytic Leukemia or Multiple Myeloma." In New Frontiers in Medicine and Medical Research Vol. 3, 26–35. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/nfmmr/v3/3152f.

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Simakova, Inna, and Roman Perkel. "Imports and Use of Palm Oil as a Way to Increase Safety of Food Fats." In Advances in Environmental Engineering and Green Technologies, 277–95. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-1042-1.ch014.

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The authors compare the biological value and safety of hydrogenated fat containing trans-isomers of oleic acid and palm oil-based fat. The chapter assesses the potential of replacing hydrogenated fats by palm oil in the production of special fat products. Hematological and histological studies are carried out in a form of biological experiment on animals (white rats). The study reveals the explicit negative effect of trans-isomers even with a relatively low concentration of trans-isomers in a diet. Pathological changes are not observed in animals when palm-based fat is introduced into their ration. The findings suggest that palm oil along with its fractions may be considered as an alternative to hydrogenated fats in the production of margarine, cooking, baking, and deep-frying fats. The use of palm oil in the production of special fats of increased hardness (spreads. confectionery, waffles and fillings, and chocolate coating) requires the application of modern methods for modifying triglyceride composition of fats – biocatalytic interesterification and fractionation.
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Kulshekar, Maya, Shridhar C. Ghagane, Sridevi I. Puranik, Rajendra B. Nerli, and Murigendra B. Hiremath. "Therapeutic Applications of Monoclonal Antibodies in Urologic-Oncology Management - An Update." In Monoclonal Antibodies [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96911.

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The idea of utilizing immunotherapy for the treatment of cancers has been appealing to scientists and clinicians for over a several decades. Immunotherapy for cancers encompasses knowledge gained from a wide range of disciplines and has the potential to procure the ‘magic bullet’ for the treatment of cancer. Monoclonal antibody-based treatment of cancer has been recognized as one of the most successful therapeutic strategies for both hematologic malignancies and solid tumours in the last 20 years. The discovery of hybridoma technology in late 1975 and the development of chimeric, humanized, and human antibodies have increased the availability and utility of immunotherapy for the treatment of cancer. Metastatic or recurrent cancer continues to be the bane of the urological oncologist. Despite recent improvements in therapeutic management and outcomes for clinically localized disease overall survival rate in patients with the majority of metastatic and recurrent genitourinary malignancies remains relatively unchanged. By targeting tumours through specific or associated antigens, it is possible to selectively eliminate tumour cells and maintain an acceptable toxicity profile. Therapeutic antibodies that target immune cells are also being developed with the goal of breaking local tolerance and stimulating the patient’s anti-tumor immune response. As with other treatment modalities, immunotherapy is far from perfect and requires additional study to optimize clinical response and overcome therapeutic resistance. Modern advances in the field of immunotherapy hold the promise of providing the clinical urologist/oncologist with new tools to fight urological cancer. However, the literature on monoclonal antibody-based immunotherapy with a particular emphasis on target antigens, monoclonal antibody design and potential applications in the field of urology is limited. Hence, the present chapter focuses on the applications of Immunotherapy using monoclonal antibodies for urologic oncology settings such as prostate, bladder, renal, testicular and penile with a hope to highlight its clinical efficacy and also its mechanisms of action in each of these cancer types.
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Conference papers on the topic "Hematological study"

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Aly, M., T. S. Meshref, M. A. Abdelhameid, S. A. Ahmed, A. S. Shaltout, A. E. Abdel-Moniem, and D. A. Hamad. "Can Hematological Ratios Predict Outcome of COVID-19 Patients? Egyptian Multicentric Study." In ERS Lung Science Conference 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/23120541.lsc-2021.54.

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Al-fatlawi, Abeer Cheaid Yousif, and Wasan Ghazi AlSafi. "Hematological study of some blood parameters for B-thalassemia major patients and effect on their fertility." In INTERNATIONAL CONFERENCE OF NUMERICAL ANALYSIS AND APPLIED MATHEMATICS ICNAAM 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0027473.

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Jenkins, Carol A., Athanassios Argiris, Ronan Swords, Anand Karnad, Martin Goros, Bradley Pollock, Zhi-Min Yuan, et al. "Abstract P3-12-04: P53 based strategy to reduce hematological toxicity of chemotherapy: A Pilot Phase II study." In Thirty-Seventh Annual CTRC-AACR San Antonio Breast Cancer Symposium; December 9-13, 2014; San Antonio, TX. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.sabcs14-p3-12-04.

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Bencomo, Alfonso E., Andres J. Rubio, Mayra A. Gonzalez, Idaly M. Olivas, Joshua J. Lara, Kiran Ghimire, Osvaldo Padilla, et al. "Abstract 4343: Retrospective study of incidence and survival for patients with hematological malignancies residing at the U.S./Mexico border." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-4343.

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Devi, Pinki, Ganapathi Bhat, and Harish S. Ahuja. "To Predict Success of Postapheresis Yield and Post–Autologous Transplant Engraftment Based on Preapheresis Peripheral Blood CD34+ Cell Counts: An Indian Scenario–Based Study." In Annual Conference of Indian Society of Medical and Paediatric Oncology (ISMPO). Thieme Medical and Scientific Publishers Pvt. Ltd., 2021. http://dx.doi.org/10.1055/s-0041-1735370.

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Abstract Introduction The use of hematopoietic stem cells for autologous and allogeneic transplantation has increased in the recent past significantly, due to introduction of newer chemotherapeutic drugs, immunological techniques, and better stem cell technology. Among the bone marrow and peripheral blood stem cells, collection of the latter being more convenient to the patient and associated with faster granulocyte and platelet engraftment has been known as preferred method for mobilization. Peripheral blood stem cells can be extracted from the autologous or allogeneic donor. Mobilization of the stem cells for autologous stem cell transplant is traditionally done using growth factors alone or in combination with chemotherapy, with or without an additional mobilizing agent. A significant number of hematological malignancy patients are poor mobilizers, (i.e., they are unable to achieve the minimal target cell dose during their first round of mobilization).Therefore, a prediction for a successful stem cell mobilization ideally should be made before initiating any apheresis procedure to spare those with a low rate of success from the risks associated with apheresis procedure. Preapheresis CD34 cell count can predict postapheresis yield and hence, can help to reduce the collection sessions. Reduction of apheresis sessions decreases the discomfort, inconvenience, time, and monetary expenses. Objectives This study was aimed to analyze preapheresis and postapheresis CD34+ cell counts. Materials and Methods Patients of any age and gender with diagnosis of hematological malignancies admitted for autologous stem cell transplantation for hematological malignancies (including Hodgkin lymphoma, non-Hodgkin lymphoma, and multiple myeloma) and germ cell tumors in our institute from July 2008 to July 2016 were included in the study. The post-GCSF CBC, preapheresis CBC, CD34+ cell counts, and postapheresis CBC, CD34+ cell counts, mononuclear cell counts to predict the outcome of amount of yield. The effect on engraftment will be measured according to the defining criteria of achieving a sustained peripheral blood neutrophil count of >500 × 106/L (Wolff 2002) and a platelet count of more than >20 × 109/L (Teltschik et al. 2016) independent of platelet transfusion for at least 7 days. Collection of stem cells was done using apheresis machine (COBE SPECTRA). Complete peripheral blood counts using automated analyzers. Peripheral blood CD34 + cell counts and postapheresis CD34+ cell count using BD FACS CANTO II flow cytometer. To calculate postapheresis yield, the related CD34 count measured by flow cytometer was multiplied by the apheresis product volume and divided by the recipient’s body weight (kg). Number of CD34+ cells collected = (CD34 cell concentration in final product) × (final product volume). Results A total of 100 patients who underwent a total of 320 apheresis sessions were included in the study. There were 78 males and 22 females. We also found a significant correlation between preapheresis CD34 + cell count and postapheresis CD34 percentage on days 1, 2, and 3 of the apheresis sessions. In our study, to obtain more than 1.31 × 106 cells (median = 1.04, range: 0.15–4.70), an absolute count of pre apheresis CD34 + cells ≥14 cells would be necessary. A target of CD34 + cells ≥ 2 × 106/kg was obtained in majority of patients if a concentration of ≥25 CD34 + cells was present in postapheresis collection. Conclusion Compiling our results with the previous published data, we conclude that there is a strong correlation between preapheresis absolute CD34 + cell counts and postapheresis CD34 + cell count. Our study also suggests that the minimum absolute cell count of >10 cells/μL is required, to achieve a target of >2–5 × 106 cells for postapheresis yield.
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Matsumoto, T., K. Kanamaru, Y. Sugiyama, and K. Deguchi. "HEMATOLOGICAL CHARACTERISTICS OF PREGNANT BLOOD AND LOCALIZATION OF THROMBOMODULIN IN HUMAN PLACENTAL VILLOUS TISSUE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644299.

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Thrombomodulin(TM) is a cell surface protein found on endothelial cell that binds thrombin and increases thrombin's ability to activate protein C(PC). In the present study, we examined hematological characteristics and behavior of plasma PC level in pregnant women and localization of TM in the placental villous tissue. The results obtained are reported here. Cubital venous blood of 20 normal pregnants, 8 purperants and 60 non-pregnants. PC antigen(PC:Ag) was measured by the Laurell's technique using Assera plate-proteinC. Localization of TM was determined in such a way that the villous tissue was fixed in formalin, cut into paraffin sections, and stained by ABC method using anti-TM antibody. Coagulation-related factors of the pregnant blood, i.e. fibrinogen, FV, FVIII, FX, FXII and prekallikren showed statistically higher values compared with the control group, and AT-III showed almost simillar value to the control group or tended to decrease to scxne extent compared therewith. As for fibrinolysis-related factors, on the other hand, plasminogen, α1-antitripsin showed higher values with the progress of pregnancy, and α2-macro_ globulin showed slightly lower values in both 3rd trimester and puerperal stage. PC:Ag increased in the 2nd and 3rd trimester (p<0.01). Comparative examinations made of PC:Ag level between pre- and post-taking oral centraceptives revealed a significant (p<0.05) decrease frcm 131.0%( pre-taking) to 117.0%(post-taking). At the 11th week of pregnancy, TM was confirmed to be highly localized in syncytiotrophoblast in the villous tissue, especially in microvilli. At the 40th week, TM was also confirmed in the same site, but with weaker stainability. It was suggested that thrombosis and hemostasis-related factors were in a state of co-existing overproduction and consumption. Moreover we supposed that the existence of TM and the increase in PC might be just appropriate for the maintenance of anti-thrombogenesis in the uteroplacental circulation.
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Agarwal, Neeraj, Mark L. Wade, Julia Batten, Cynthia Davidson, Show-Li Sun, and Sunil Sharma. "Abstract 1172: Phase I study of histone deacetylase inhibitor belinostat in combination with warfarin in patients with solid tumors or hematological malignancies." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-1172.

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Medichelme, Chaitanya, Shagun Juneja, Anirudh Punnakal, Charu Garg, Indu Bansal, Amal Roy Chaudhoory, Anil Kumar Bansal, and Anil Kumar Anand. "Retrospective analysis of acute and late gastrointestinal and hematological toxicities with extended field radiation in gynaecological malignancies: A single institution data." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685352.

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Purpose: The aim of this study is to report a preliminary analysis of our clinical experience with extended field pelvic (conformal) radiation, with or without concurrent chemotherapy, in gynaecological malignancies. Materials and Methods: 27 women with gynaecological malignancies (17 with Carcinoma Cervix and 10 with Carcinoma Endometrium) were treated between November 2009 and October 2015 with Extended Field abdomino-pelvic radiation. All patients were treated with conformal radiation (Intensity Modulated Radiotherpy or Volumetric Modulated Arc Therapy). All patients underwent CT Simulation followed by target and OAR delineation as per RTOG guidelines. Dose prescriped was 45-50 Gy in 1.8 Gy per fraction and boost to gross node upto 54-56 Gy. Planning was done on Eclipse Planning system, and treatment was delivered on 6 MV linac. Concurrent chemotherapy was given when indicated. All toxicities were scored according to Common Terminology Criteria for Adverse Events (CTCAE v 4.03). Dosimetric parameters were correlated with toxicities. Results: Median follow up was 9.5 months (Range 0-52 months). 14 (51.8%) patients developed Grade 1 and 2 acute hematological toxicity and 1 (0.04%) developed Grade 3 toxicity. 10 (37%) patients developed Grade 1 and 2 acute gastrointestinal toxicity and 1 (0.04%) developed grade 4 toxicity. 3 (11.12%) patients had late toxicity in the form of prolonged leucopenia, SAIO, and Irritable Bowel Syndrome. 1 patient did not complete her treatment due to persistent leucopenia (Grade 3). Conclusion: Extended field Radiation in Gynaecological malignancies is a reasonably well tolerated procedure when treated with IMRT or VMAT, with acceptable toxicity profile.
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Ozoux, Marie-Laure L., Hélène Guillemin, Marie-Hélène H. Pascual, Sylvaine Cartot-Cotton, Christine Veyrat-Follet, Delphine Valente, Maxime Moulard, Christine Mauriac, Antoine Deslandes, and Dorothee Semiond. "Abstract 2908: A first-in-human phase I study of SAR650984, a humanized anti-CD38 antibody in patients with CD38+ hematological malignancies: Preliminary PK and PD results of escalation phase." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2908.

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"Study of hematologic malignancy vaccines." In International Conference on Medicine, Public Health and Biological Sciences. CASRP Publishing Company, Ltd. Uk, 2016. http://dx.doi.org/10.18869/mphbs.2016.117.

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