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Journal articles on the topic 'Hematological study'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

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1

K, Shivani Shenoy, Raj Shekhar, Mary Mathew, and G. Arun Kumar. "A Clinico-Hematological Study of Influenza Virus Infection." Academia Journal of Medicine 2, no. 2 (July 24, 2019): 24–27. http://dx.doi.org/10.21276/ajm.2019.2.2.8.

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Makadia, Khushbu Dalasukhbhai, and Pragnesh Shah. "A Study of Hematological Changes in Neonatal Sepsis." Annals of Pathology and Laboratory Medicine 7, no. 5 (May 28, 2020): A236–240. http://dx.doi.org/10.21276/apalm.2792.

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J., Joshi Hetal. "A Study of Different Hematological Parameters in Malaria." Journal of Medical Science And clinical Research 05, no. 05 (May 6, 2017): 21503–8. http://dx.doi.org/10.18535/jmscr/v5i5.46.

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N., Gayathri B., and Kadam Satyanarayan Rao. "Pancytopenia: A Clinico Hematological Study." Journal of Laboratory Physicians 3, no. 01 (January 2011): 015–20. http://dx.doi.org/10.4103/0974-2727.78555.

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ABSTRACT Background: Pancytopenia is a relatively common hematological entity. It is a striking feature of many serious and life-threatening illnesses, ranging from simple drug-induced bone marrow hypoplasia, megaloblastic anemia to fatal bone marrow aplasias and leukemias. The severity of pancytopenia and the underlying pathology determine the management and prognosis. Thus, identification of the correct cause will help in implementing appropriate therapy. Objectives: To study the clinical presentations in pancytopenia due to various causes; and to evaluate hematological parameters, including bone marrow aspiration. Materials and Methods: It was a prospective study, and 104 pancytopenic patients were evaluated clinically, along with hematological parameters and bone marrow aspiration in Hematology Unit, Department of Pathology, JJMMC, Davanagere, during the period of September 2005 to September 2007. Results: Among 104 cases studied, age of patients ranged from 2 to 80 years with a mean age of 41 years, and male predominance. Most of the patients presented with generalized weakness and fever. The commonest physical finding was pallor, followed by splenomegaly and hepatomegaly. Dimorphic anemia was the predominant blood picture. Bone marrow aspiration was conclusive in all cases. The commonest marrow finding was hypercellularity with megaloblastic erythropoiesis. The commonest cause for pancytopenia was megaloblastic anemia (74.04%), followed by aplastic anemia (18.26%). Conclusion: The present study concludes that detailed primary hematological investigations along with bone marrow aspiration in cytopenic patients are helpful for understanding disease process and to diagnose or to rule out the causes of cytopenia. These are also helpful in planning further investigations and management.

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Manzoor, Fahim, ManjiriN Karandikar, and RavindraC Nimbargi. "Pancytopenia: A clinico-hematological study." Medical Journal of Dr. D.Y. Patil University 7, no. 1 (2014): 25. http://dx.doi.org/10.4103/0975-2870.122763.

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Gangat, Naseema, Aneel A. Ashrani, Tanya M. Petterson, Jeffery Schmoll, and John A. Heit. "Hazard of Subsequent Hematological Cancer in Patients with Incident Venous Thromboembolism (VTE): A Population-Based Cohort Study." Blood 110, no. 11 (November 16, 2007): 2154. http://dx.doi.org/10.1182/blood.v110.11.2154.2154.

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Abstract Background: While currently-diagnosable hematological cancer is a potent VTE risk factor (RR range =12–32), whether undiagnosable hematological cancer is a risk factor is uncertain. Objective: To estimate the hazard of subsequent hematological cancer among incident VTE patients with no apparent active hematological cancer within ± 3 months of the VTE event. Methods: In a population-based cohort study, we followed Olmsted County, MN residents with incident VTE over the 27-year period, 1973–1999, and previously matched Olmsted County residents without VTE, who survived with no apparent active hematological cancer within ± 3 months of the VTE event or a routine medical visit date, respectively, forward in time through their complete medical records in the community for hematological cancer. Data were abstracted on baseline demographic and clinical characteristics, type and stage of hematological cancer, and any prior solid tumor treatments. For cases and controls, hematological cancer-free survival from the event date was estimated by the Kaplan Meier method, and the homogeneity of survival curves was examined by the log-rank test. Cox proportional hazards regression was used to adjust for covariates. Results: 1860 VTE cases (56% females) and 1890 controls (53% females) were followed for 16,497 and 15,320 person-years, respectively, conditional on surviving 3-months free of hematological cancer. 43 VTE cases and 24 controls developed hematological cancer at a median of 63.5 months (range 0.7 – 334 months). The median age for cases was 63.2 years compared to 67.8 years for the controls (p<0.001). Hematological cancer types included non-Hodgkin’s lymphoma (n=19), chronic lymphocytic leukemia (n=11), acute myeloid leukemia (n=1), multiple myeloma (n=9), myeloproliferative disorders (n=10), and myelodysplastic syndromes (n=14). Case status was not univariately associated with subsequent hematologic cancer (HR=1.42; 95% CI: 0.85, 2.39; p=0.18). After adjusting for age, also associated with cancer, case status was significantly associated with hematological cancer (HR=1.90; 95% CI: 1.13, 3.20; p=0.015). Conclusions: Incident VTE patients have nearly a two-fold increased risk of subsequent hematological cancer. We hypothesize that VTE can be the initial manifestation of an occult hematological cancer clone.

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Waghmare, Tejaswini, Daksha Prabhat, and Naveen Vairamoorthy D. "A Clinico-Hematological Study of Cases of Leucoerythroblastic Reaction." Annals of Pathology and Laboratory Medicine 6, no. 2 (February 15, 2019): A103–111. http://dx.doi.org/10.21276/apalm.2410.

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Kumar Koirala, Prakash, Bidita Khandelwal, and Forhad A. Zaman. "Study of Hematological Profile and Effect of Antitubercular Medications on the Hematological Derangements in Patients Suffering from Tuberculosis." Indian Journal of Emergency Medicine 3, no. 1 (2017): 45–50. http://dx.doi.org/10.21088/ijem.2395.311x.3117.7.

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Prasanna, N., Punyashetty Kajal B., Ananthrao Anand Shankar, and Patil Tejeshwini. "Clinico-Hematological Profile in Dengue: A Tertiary Care Institutional Study." Indian Journal of Pathology: Research and Practice 6, no. 1 (2017): 75–81. http://dx.doi.org/10.21088/ijprp.2278.148x.6117.12.

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S., Arundhathi, Sunitha S., Balumahendran K., and Rajeev Gandham. "A Case- Control Study on Hematological Profile in Thyroid Dysfunction." Indian Journal of Pathology: Research and Practice 7, no. 5 (2018): 592–94. http://dx.doi.org/10.21088/ijprp.2278.148x.7518.3.

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Marisetty, Manikantaswamy, Prabhu Mural H, and Shankara Shivamurthayya Hiremath. "Clinico-Hematological Study of Megaloblastic Anemia and Associated Megakaryocytic Alterations." Indian Journal of Pathology: Research and Practice 8, no. 2 (2019): 181–88. http://dx.doi.org/10.21088/ijprp.2278.148x.8219.9.

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Angel S, Dr Evelyn, Dr Sivasankaran M, and Dr Elizabeth Chacko. "Dengue: a clinical & hematological study." Tropical Journal of Pathology and Microbiology 3, no. 3 (September 30, 2017): 340–46. http://dx.doi.org/10.17511/jopm.2017.i03.20.

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Das, Swapan. "Study of Hematological Parameters in Pregnancy." IOSR Journal of Dental and Medical Sciences 12, no. 1 (2013): 42–44. http://dx.doi.org/10.9790/0853-1214244.

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Meimandi Parizi, A., and J. Khalafizadeh. "Hematological study of lameness in cattle." Comparative Clinical Pathology 15, no. 3 (August 3, 2006): 189–90. http://dx.doi.org/10.1007/s00580-006-0626-2.

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Hanif, Umair, Mughees Ahmed, and Imran Hanif. "HEMATOLOGICAL MALIGNANCIES." Professional Medical Journal 22, no. 03 (March 10, 2015): 349–52. http://dx.doi.org/10.29309/tpmj/2015.22.03.1354.

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Infection rate of CMV in adults is approximately 60% in the developed countriesand almost 100% in the developing countries. Objectives: To evaluate the frequency ofcytomegalovirus (CMV) infection in patients with different hematological malignancies. Design:Observational study. Setting: Gulab Devi Chest Hospital & INMOL Hospital Lahore. Period: Sixmonths. Materials and methods: The blood samples were drawn from the selected patientsafter taking their written informed consent. The DNA was extracted from the whole blood andthe polymerase chain reaction was performed for CMV DNA using CMV PCR kit (CinnagenInc. Catalog # PR7836C). The 222bp fragment corresponding to the size marker and positivecontrol was considered as positive. The data was analyzed by SPSS version 16. Results: Themean age of patients was 36 years. Out of 16, 3 were presented with interstitial pneumonitis, 14with retinitis, 3 with esophagitis and 5 were presented with colitis respectively. In this study onesample was tested positive for CMV DNA. Conclusions: CMV infection may be a serious threatfor the patients with compromised immune system such as those receiving chemotherapy. Thescreening for CMV should be done before the blood transfusion to such patients.

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Rai, Shalini. "Study of Hematological Parameters in Patients of Different Subtypes of Panduroga." JOURNAL OF ADVANCED RESEARCH IN AYURVEDA, YOGA, UNANI, SIDHHA & HOMEOPATHY 05, no. 03 (December 26, 2018): 6–12. http://dx.doi.org/10.24321/2394.6547.201813.

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Chaudhari, NilimaMahendrabhai, and Shaila Shah. "Hematological Manifestation in Lung, Breast and Git Malignencies :A Discriptive Study." Annals of Pathology and Laboratory Medicine 5, no. 5 (May 29, 2018): A384–388. http://dx.doi.org/10.21276/apalm.1750.

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Montagna, M. T., G. Lovero, C. Coretti, D. Martinelli, M. Delia, O. De Giglio, M. Caira, et al. "SIMIFF study: Italian fungal registry of mold infections in hematological and non-hematological patients." Infection 42, no. 1 (October 23, 2013): 141–51. http://dx.doi.org/10.1007/s15010-013-0539-3.

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Yadav, Rakesh Kumar, and Sujit Kumar. "To study hematological profile in malaria patients." International Journal of Advances in Medicine 4, no. 3 (May 23, 2017): 707. http://dx.doi.org/10.18203/2349-3933.ijam20172132.

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Background: Malaria has been a problem in India for centuries and it is responsible for many deaths in rural areas. This study was done to observe hematological profile in malaria patients and to study the incidence of complications in different species of malaria patients and to find any relation with hematological changes.Methods: The study was conducted at MLN Medical College, Allahabad in the Department of Medicine between January 2016 to December 2016. One hundred consecutive patients aged 18 years or more with malaria fever were interviewed and examined.Results: Out of 100 patients 26 patients had Plasmodium vivax malaria and 59 patients had Plasmodium falciparum infection while 15 patients had mixed PV and PF infection. In present study thrombocytopenia was most common hematological abnormality. Thrombocytopenia was present in 87 patients, out of them 18 had very severe thrombocytopenia while 69 had mild to moderate thrombocytopenia. Frank bleeding was present in 14 of total studied population and had both PV and PF infection. Petechial rashes were present in 10 patients. Anemia was present in 80 patients.Conclusions: Thrombocytopenia is very frequent finding in patients suffering from malaria, and even in presence of thrombocytopenia bleeding manifestations are uncommon. So, platelet transfusion should not be performed routinely in all thrombocytopenia patients, rather it should be indicated only if bleeding manifestations are present. Anemia, pancytopenia and leucopenia are other frequent laboratory findings of malaria infection.

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Kumar M.D, Dr S. Siva, and Dr N. Kirubanand M.D. "A Study on Hematological Manifestations in Tuberculosis." IOSR Journal of Dental and Medical Sciences 15, no. 07 (July 2016): 08–11. http://dx.doi.org/10.9790/0853-150730811.

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Dale, David C., Audrey Anna Bolyard, Laurie A. Steele, Cornelia Zeidler, and Karl Welte. "Registries for study of nonmalignant hematological diseases." Current Opinion in Hematology 27, no. 1 (January 2020): 18–26. http://dx.doi.org/10.1097/moh.0000000000000558.

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Bjelakovic, Gordana, Tatjana Jevtovic-Stoimenov, Ivana Stojanovic, Bojko Bjelakovic, and Mira Ilic. "Biochemical study of hematological diseases in childhood." Jugoslovenska medicinska biohemija 22, no. 2 (2003): 141–49. http://dx.doi.org/10.2298/jmh0302141b.

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Hematological diseases in childhood occur frequently. Analyses of hematological status as well as standard biochemical analysis of blood, as a result of hematopoetic system function, are of great importance in detection and recognition of these diseases. All hematological diseases appear as disturbance of hematopoetic system function at the level of the production and viability in blood flow; this disturbance is reflected on the hemogram and biochemical analyses of blood plasma and serum. The basic hematological parameters of blood diseases (except disturbance of blood coagulation) are Total blood count cells (erythrocytes, leukocytes with differential leukocytes formulae, trombocytes) hemoglobin concentration, amount of hematocrit (PCV, packed cell volume), erythrocytes sedimentation rate erythrocytes osmotic fragility. Among the standard biochemical analysis the determination of total bilirubin in the calculation fraction of indirect bilirubin, the amount of serum iron and transferrine (TIBC), serum copper and ceruloplasmin are in use in these diseases. Hemoglobin electrophoresis is also use. The measurement of lactate dehydrogenase activity and other enzymological analyses are rarely performed. The basic idea of this report is the evaluation of another biochemical possibility with the aim to understand the nature of hematological disorders by the use a large spectrum of enzyme analyses, which are present in different blood cells and with direct reflection on the serum enzyme activities.

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Lopez-Jornet, Pia, Fabio Camacho-Alonso, and Nieves Martos. "Hematological study of patients with aphthous stomatitis." International Journal of Dermatology 53, no. 2 (July 24, 2013): 159–63. http://dx.doi.org/10.1111/j.1365-4632.2012.05751.x.

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Akhtar, Dr Shamim. "Hematological changes in malaria: A comparative study." IOSR Journal of Pharmacy and Biological Sciences 2, no. 4 (2012): 15–19. http://dx.doi.org/10.9790/3008-0241519.

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Kornienko, M. N., T. N. Rybalkina, N. V. Karazhas, G. Yu Nikitina, M. Yu Kalugina, L. V. Yarosh, and T. A. Semenenko. "Identification of markers of opportunistic infections and viral hepatitis in oncohematological patients." Epidemiology and Infectious Diseases 20, no. 6 (December 15, 2015): 33–38. http://dx.doi.org/10.17816/eid40888.

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The purpose of the study To estimate the prevalence of markers of herpesvirus infections and pneumocystosis in patients of the hematological department. To identify whether the contamination of hematological patients with hepatitis B and C (HBV, HCV) affects on the activation of opportunistic infections (OIs). Materials and methods There were examined 94 patients of the hematological department, including 48 patients with markers of HBV infection and 46 cases without them. Obtained results Markers of acute OIs (simple herpes virus type 1- 6,4%, EBV - 14,9%, CMV - 6,4%, and Human Herpesvirus 6- 13,8% and 33,0% of pneumocystosis) in hematological patients were determined more frequently than in donors. Comparative analysis of the data revealed the excess of the proportion of cases with markers of acute HHV-6 infection in hematological HBV patients in comparison with a group of hematologic patients without markers of HBV infection (22,9% against 4,4%, p

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Vaibhaw, Harshita, E. Girikumar, Dilip Hari Mandke, and Ravi Nandan Prasad Sinha. "Clinico-Hematological Study of Pancytopenia in Adults at a Tertiary Care Center." Asian Journal of Medical Research 8, no. 1 (March 2019): PT08—PT10. http://dx.doi.org/10.21276/ajmr.2019.8.1.pt3.

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Patel, ReenalRohit, Manisha Tambekar, and Reeta Dhar. "Clinico-hematological analysis of pancytopenia in adults – A two year prospective study." Annals of Pathology and Laboratory Medicine 5, no. 2 (2018): A122–128. http://dx.doi.org/10.21276/apalm.1519.

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Ciftciler, Rafiye, Aysel Pasayeva, Salih Aksu, Osman Ozcebe, Nilgun Sayınalp, Umit Yavuz Malkan, Yahya Buyukasık, and Ibrahim C. Haznedaroglu. "Indications and outcomes of splenectomy for hematological disorders." Open Medicine 14, no. 1 (June 17, 2019): 491–96. http://dx.doi.org/10.1515/med-2019-0054.

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AbstractBackground and AimSplenectomy is a frequent component of the diagnosis and treatment of hematological disorders. The aim of this study was to define the indications and outcomes of splenectomy for benign and malign hematological disorders.Materials and MethodsOne hundred and two patients with hematological disease who had splenectomy at Hacettepe University Hospital between the years of 2010 and 2018 were evaluated.ResultsA total of one hundred and two patients were included in this study. The median age was 52 (20-82) years at the time of splenectomy. Most of the patients were female (57.9%). The median follow up time was 11.0 (0.03-87.9) months after splenectomy. Splenectomy was performed to diagnose thirty patients (29.4%). Seventy-two patients underwent splenectomy for the treatment of hematological disease (70.6%). Twenty-seven patients (90%) were diagnosed with various lymphomas. Two patients (6.7%) were diagnosed with hairy cell leukemia and one patient (3.3%) was diagnosed with large granular lymphocytic leukemia.ConclusionIn conclusion, an improvement in medical therapy, especially with monoclonal antibodies, the indications and outcomes of splenectomy for hematologic disorders have changed extremely in last years. Nevertheless, splenectomy has an important role for diagnosis and treatment of benign and malign hematological disorders.

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Ain, Noor ul, Nusrat Bano, Anwar Ejaz Beg, Kamran Hameed, Talha Bin Fayyaz, and Rafia Sadaf. "HEMATOLOGICAL TOXICITY IN RATS;." Professional Medical Journal 24, no. 02 (February 14, 2017): 342–46. http://dx.doi.org/10.29309/tpmj/2017.24.02.525.

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Objectives: Oxaliplatin causes hematological toxicities in clinical setting whichlimits its efficacy. The aim of this study is to investigate the therapeutic effects of Andrographispaniculata against hematological toxicity caused by oxaliplatin. Study design: Experimentalanimal study. Period: Study takes 8 month from March 2015 to Oct 2015. Setting: Dow universityanimal house. Method: Wistar albino male rats, divided into 3 equals groups (n=6): GroupN* was a control group (0.9% normal saline), Group NP0 was Oxaliplatin treated group andGroup NP1 was prophylactically treated with Andrographis paniculata followed by Oxaliplatinin order to assess the protective effects of Andrographis paniculata against the hematologictoxicity caused by Oxaliplatin. Results: Prophylactic treatment with Andrographis paniculata(NP1) significantly increases the levels of platelets and neutrophile count compared with thestandard (NP0) (p<0.01) and increases the RBCs count and levels of hemoglobin comparedwith the standard (NP0). Conclusion: Prophylactic treatment with Andrographis paniculata(NP1) was effective in reducing risk of thrombocytopenia, anemia and neutropenia associatedwith Oxaliplatin.

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KHAN, SIKANDAR HAYAT, and MUHAMMAD FAROOQ. "VIVAX MALARIA; HEMATOLOGICAL CHANGES: A STUDY AT KARACHI." PROFESSIONAL MEDICAL JOURNAL 24, no. 06 (June 1, 2017): 859–64. http://dx.doi.org/10.17957/tpmj/17.3782.

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Nikethan, B., V. Chaitanya, Suresh Hanagavadi, and S. S. Hiremath. "A Clinico-Hematological Study of Congenital Bleeding Disorders." Indian Journal of Public Health Research & Development 6, no. 4 (2015): 210. http://dx.doi.org/10.5958/0976-5506.2015.00229.6.

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Arul, Dr R., and Dr P. Praveen Kumar. "Study Of Hematological Profile In Rheumatoid Arthritis Patients." IOSR Journal of Dental and Medical Sciences 15, no. 09 (September 2016): 96–100. http://dx.doi.org/10.9790/0853-15090496100.

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Sharan, Dr Anita, and Dr Sagar Shah. "Study of hematological parameters in anemia in pregnancy." Tropical Journal of Pathology and Microbiology 5, no. 10 (October 31, 2019): 762–69. http://dx.doi.org/10.17511/jopm.2019.i10.03.

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Banasode, Indrani N., and Ashraf A. Zubair. "A prospective study of hematological parameters in malaria." MedPulse - International Journal of Pathology 10, no. 2 (2019): 120–23. http://dx.doi.org/10.26611/10510212.

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Abdel-Rahman, Ali A., Yamen, M. Hegazy, Khaled Sultan, and Magdy H. Al-Gaabary. "CLINICAL, HEMATOLOGICAL AND PARASITOLOGICAL STUDY ON CANINE BABESIOSIS." Kafrelsheikh Veterinary Medical Journal 13, no. 2 (October 1, 2015): 37–47. http://dx.doi.org/10.21608/kvmj.2015.109779.

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Budihal, Dr Nischita. "Hematological parameters in fever evaluation - A prospective study." International Journal of Clinical and Diagnostic Pathology 2, no. 2 (July 1, 2019): 99–102. http://dx.doi.org/10.33545/pathol.2019.v2.i2b.87.

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Journal, Baghdad Science. "Hematological Study of Infants Amoebiasis in Duhok City." Baghdad Science Journal 14, no. 2 (June 4, 2017): 343–48. http://dx.doi.org/10.21123/bsj.14.2.343-348.

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Out of 180 children, 60 (33.3%) have Amoebiasis infection as diagnosed by direct wet smear and Saturated Salt Solution (SSS). SSS method is more significant (P=0.001) in diagnosis of the disease. Number of children infected with Amoebiasis infection is higher in infants aged 1-6 months, but without any significant difference to ages 6-12 or 12-18 months. In contrast, infants aged 18-24 months are significantly differant (P=0.01) as the infection rate is 16.6%. Gender also is seen to be reduced in significance (P= 0.001) for females aged 18-24 months. Blood profile of the involved infants has shown a significant variation (P=0. 01) for all blood profile parameters (RBC (P=0.05), WBC (P=0.001), Lymphocytes (P=0.05), Granulated WBC (P=0.05), Hb (P=0.01) and Platelets counts (P=0.001). Many medicinal regimes are dependent in the treatment of Amoebiasis, Metronidazole (Flagyl) in significant variation (P=0.01), combination of Metronidazole and Bactrim

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Szuba, Andrzej, Angelika Chachaj, Tomasz Wróbel, Justyna Dzietczenia, Grzegorz Mazur, Jolanta Antonowicz-Juchniewicz, Kazimierz Kuliczkowski, and Ryszard Andrzejak. "Asymmetric dimethylarginine in hematological malignancies: a preliminary study." Leukemia & Lymphoma 49, no. 12 (January 2008): 2316–20. http://dx.doi.org/10.1080/10428190802510323.

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Abed, R. El, V. Bourdon, L. Huiart, F. Eisinger, A. Khelif, M. Frenay, P. Gesta, et al. "Molecular study of CEPBA in familial hematological malignancies." Familial Cancer 8, no. 4 (September 3, 2009): 581–84. http://dx.doi.org/10.1007/s10689-009-9289-x.

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Xavier, Ana Carolina Galtarossa, Sheila Aparecida Coelho Siqueira, Luciano Jos� Megale Costa, Thais Mauad, and Paulo Hil�rio Nascimento Saldiva. "Missed diagnosis in hematological patients?an autopsy study." Virchows Archiv 446, no. 3 (February 15, 2005): 225–31. http://dx.doi.org/10.1007/s00428-004-1186-y.

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Mengistu Sissay, Teklay, Melatwork Tibebu, Tagesachew Wasihun, and Aster Tsegaye. "Hematological reference intervals for adult population of Dire Dawa town, East Ethiopia." PLOS ONE 16, no. 2 (February 16, 2021): e0244314. http://dx.doi.org/10.1371/journal.pone.0244314.

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Background Reference interval (RI) for hematological parameters is used to interpret laboratory test results in the diagnosis, management and monitoring of hematologic disorders. Several factors including sex, age, dietary patterns, pregnancy status, ethnicity and geographic location affect hematological RIs. However, manufacturers derived reference value is currently in use in most developing countries including Ethiopia. This study aimed to establish hematological RIs for adult population living in Dire Dawa town, East Ethiopia. Methods In this cross-sectional study, 513 apparently healthy adults of Dire Dawa town were enrolled from January to March 2019. From these, 342 (171 males and 171 non-pregnant females) were aged 18–65 years while 171 were pregnant women aged 15–49 years. After obtaining written informed consent, 5ml fresh whole blood was collected of which 2ml was used for hematologic analysis using Mindray BC-3000plus hematology analyzer and 3ml for serological tests. The 2.5th and 97.5th RI was computed by non-parametric test employing SPSS version 24. P-value <0.05 was considered statistically significant. Result Males had significantly higher reference value for most of red cell parameters (Hgb, RBC, HCT, MCH and MCHC) than females (p <0.05), while most of the WBC parameters were significantly higher in females than males. Moreover, non-pregnant women had higher values for most of red cell parameters than pregnant women. Pregnant women had higher WBC parameters than their non-pregnant counterparts. Conclusion The hematologic RIs obtained in this study shows variation between genders, between pregnant and non-pregnant women, from the clinical practice currently utilised in Dire Dawa town and from studies conducted in Ethiopia, African countries as well as the Western population. It underscores the need for utilising gender and pregnancy specific, locally derived hematologic RI for better management, diagnosis and monitoring of hematologic disorders for adults of both genders and pregnant women.

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Baiguzhekov, M. "THE STUDY OF HEMATOLOGICAL AND FUNCTIONAL INDICATORS IN STUDENTS DURING THE EXAMINATION SESSION." Journal of Educational Sciences 54, no. 1 (2018): 51–58. http://dx.doi.org/10.26577/jes-2018-1-489.

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De, Puspal, and Madhumitha J. Mukhopadhyay. "Study of the Chromosomal Abnormalities and Associated Complex Karyotypes in Hematological Cancer in the Population of West Bengal: A Prospective Observational Study." Indian Journal of Medical and Paediatric Oncology 42, no. 03 (May 2021): 261–67. http://dx.doi.org/10.1055/s-0041-1733827.

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Abstract Introduction Chromosomal instability is an important feature of hematological cancer. The pathogenesis is complex and it involves genetic and epigenetic factors. As a genetic factor, chromosomal instability may play a key role in leukemogenesis. Accumulation of genetic alteration is mainly responsible for numerical and structural chromosomal rearrangement or clonal evaluation. But disease progression is often driven by chromosomal translocation, hyper- or hypodiploidy with structural abnormalities, and complex karyotypes. Objective This research aimed to study the different types of chromosomal abnormalities in clinically suspected hematological cancer patients. Materials and Methods Cytogenetic analysis was performed based on phytohemaglutinin stimulated peripheral blood lymphocyte cultures and bone marrow culture, without mitogen, of the respective patients of West Bengal from March 2016 to February 2018. All clinically suspected hematological cancer patients referred for karyotyping to the institutional genetics department have been included without any biasness of sex and age. Karyotypes were described according to the International System for Cytogenetic Nomenclature (ISCN 2005). Results In the present study, 56 clinically suspected hematological cancer cases were observed and 41 cases of chromosomal rearrangement were found which clearly show chromosomal instability as the main driving force for hematological cancer transformation. Presence of variant Philadelphia chromosomes with classical translocation, mosaic complex karyotypes, variable numerical, and structural chromosomal abnormality, along with severe-to-moderate hypo- and hyperdiploidy, and presence of marker chromosomes were the main findings of this study. Conclusion The result shows that the detection of chromosomal instability was important for preliminary diagnosis, treatment, prognosis, and further management. So the present study provided additional information about chromosomal instability in hematological cancer at Kolkata and adjoining regions.

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Ashrani, Aneel A., John A. Heit, Jeffrey A. Schmoll, Sara A. Farmer, Tanya M. Petterson, and Lee J. Melton. "Risk Factors for Venous Thromboembolism (VTE) among Patients with Active Hematological Cancer: A Population-Based Case-Control Study." Blood 110, no. 11 (November 16, 2007): 1642. http://dx.doi.org/10.1182/blood.v110.11.1642.1642.

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Abstract Background: Hematological cancer patients are at an increased risk for VTE (RR range = 12–32). However, whether VTE risk among such patients can be further stratified is uncertain. Objective: To test hematological cancer type, stage, stage progression and chemotherapy as potential risk factors for VTE among active hematological cancer patients after controlling for other previously-identified VTE risk factors. Methods: Using the resources of the Rochester Epidemiology Project, Mayo Clinic Master Diagnostic Index and Mayo Clinic Tumor Registry, we identified all Olmsted County, MN residents with active hematological cancer over the 28-year period, 1973–2000. From this prevalence cohort, we identified 86 patients with no prior VTE (controls) who were matched on age and date of hematological cancer diagnosis to 86 hematological cancer patients with incident VTE over the same time frame (cases). For all cases and controls, we reviewed the complete medical records in the community for baseline and hematological cancer-related characteristics. Hematological cancers were re-staged at the dates of the cancer and VTE diagnosis. We tested these characteristics as potential risk factors for VTE in active hematological cancer using conditional logistic regression. Results: In an initial multivariate analysis that included body mass index (BMI), hospitalization, and any infection or central venous catheter placement within 90 days prior to the VTE event, VTE was significantly associated with hospitalization (OR=6.70; p<0.001), and marginally associated with any infection (OR=2.18; p=0.09). After adjusting for the above variables, chemotherapy administered within the preceding 90 days was significantly associated with VTE (OR=4.25; p=0.02), while stage progression was marginally associated (OR=4.79; p=0.10). Compared to all other hematological cancer types, acute leukemia (OR=5.95; p=0.01) and non-Hodgkin’s lymphoma (OR=2.61; p=0.01) were associated with VTE. However, after adjusting for BMI, hospitalization, any infection and central venous catheter, only non-Hodgkin’s lymphoma was independently associated with VTE (OR=3.79, p=0.009), while acute leukemia was not (OR=2.66, p=0.35). Conclusions: Hematological cancer type (in particular, non-Hodgkin’s lymphoma and possibly acute leukemia), recent hospitalization, recent chemotherapy, and possibly stage progression and recent infection, are risk factors for VTE among patients with active hematological cancer.

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Muhammadsalih, Mehri Mirhaj, Rezhna Adil Rashid, and Rowkhosh Ishaq Mekha. "A comparative study between normal and chronic kidney patients during Hemodialysis." Journal of University of Raparin 6, no. 1 (June 28, 2019): 184–94. http://dx.doi.org/10.26750/vol(6).no(1).paper11.

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The present study, included 71 patients (41males and 30 females), suffering from chronic renal failure, who were attending Kidney Dialysis Center of Hawler Teaching Hospital in Erbil government, and 50 healthy individuals included as a control group. The sera were separated from patients and controls blood samples subjected to hematological studies. The aim of this study was to estimate changes in various hematological parameters in chronic renal failure patients before and after hemodialysis. The study results showed that most of the hematological parameters were changed by hemodialysis in chronic kidney disease. Erythrocytes, hemoglobin, hematocrite were found to increase post-HD. The mean corpuscular volume, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration showed mild increase after hemodialysis. Leukocyte and platelet counts also showed mild increase after hemodialysis. It can be concluded that complete hematological parameters were found to increase after hemodialysis. Therefore, it is recommended that patients on hemodialysis should be investigated before and after hemodialysis to control the risk of anemia, bleeding or thrombosis.

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Atyha, Amal Hassen. "Study the effects of naturally acquired canine Dirofil Ariasis on some hematological and biochemical parameters." Iraqi Journal of Veterinary Medicine 41, no. 1 (June 5, 2017): 104–8. http://dx.doi.org/10.30539/iraqijvm.v41i1.90.

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The present study was aimed to check the amount of variation in some hematologic and biochemical parameters accompanied with natural acquired canine dirofilariasis. Blood samples were collected from sixty five stray dogs (5-10) years old belong to local breed dog in the villages of Al-Hindya area/ Karbala Governorate, The affected animal showed differences in hematological and biochemical values as compared with reference ranges. In conclusion, the disease showed no significant clinical signs although many pathological changes in some blood constituent with serum biochemical parameters were observed, before euthanasia for dogs.

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Yuniza, Filia, Eddy Mart Salim, Nova Kurniati, Harun Hudari, Erial Bahar, Agustian Dwi Putra, Sri Sulpha Siregar, and Guntur Baruara. "N-Acetylcystein has Potential Effect to Reduce Haematological Abnormalities in HIV/AIDS Patients Undergoing ARV Treatment." Journal of Drug Delivery and Therapeutics 10, no. 4-s (August 20, 2020): 197–200. http://dx.doi.org/10.22270/jddt.v10i4-s.4319.

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Aims: to determine the effect of NAC administration on hematological abnormalities in HIV/AIDS patients who are undergoing ARV treatment. Method: This was a pilot study using a double blind randomized clinical trial. A total of 32 subjects who met the inclusion and exclusion criteria were divided into 2 groups, namely placebo and NAC. Subjects in the NAC group were given NAC at a dose of 3x200 mg/day, while the placebo group was given lactose at a dose of 3x200 mg/day. Each group was given treatment for 12 weeks. Before and after treatment, subjects were examined for hematologic parameters. Results: Most of subjects had normal hematological features. NAC administration did not have a significant effect on the mean levels of Hb, Ht, number of erythrocytes, leukocytes and platelets (p> 0.05). However, NAC administration can reduce the degree of anemia and improve the condition of thrombocytopenia, leukopenia and lymphopenia. Conclusion: NAC administration can reduce hematological abnormalities HIV/AIDS patients undergoing ARV treatment. Keywords: ARV, Hematological abnormalities, HIV/AIDS, NAC.

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Zhiguleva, L. Yu. "Current structure, organization and evaluation of effectiveness of the specialized outpatient medical care for patients with blood diseases in a metropolis." Kazan medical journal 95, no. 2 (April 15, 2014): 261–67. http://dx.doi.org/10.17816/kmj2077.

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Aim. To analyze the structure, organization and effectiveness of outpatient medical care for patients with blood diseases in St. Petersburg, Russia. Methods. 83 reports submitted by the heads of hematological offices at 2000-2012 were analyzed. The effectiveness was evaluated using routine statistical tests. The prevalence of the diseases was assessed by registration forms №7, 35, the data provided by information and analytical center of the Healthcare Committee and the City cancer registry. Medical aid provided to patients at 2010-2012 was studied, for this purpose 250 outpatient files (025/y form) were randomly picked out, the data were collected using specially designed registration cards (254 parameters). Results. Municipal, federal and departmental institutions provide hematologic outpatient medical care in St. Petersburg. The major burden of providing medical care to hematologic patients lays on interdistrict hematological offices, which actively follow-up and treat patients with hematologic cancers. Every sixth patient has complications, and 75% - comorbidities. During the period of study, the attendance rate increased by 33.4% (from 64 766 in 2000 to 86 405 in 2012), the number of the newly-diagnosed patients with hematologic cancers increased by 13.9% (p 0.05), the share of patients with hematologic cancers increased from 28.0 to 50.4%. Cumulative incidence of lymphomas increased from 69.9 to 96.0 per 100 thousand of population; leukemia - from 49.7 to 79.3. Mortality due to lymphomas decreased from 8.1% in 2001 to 5.3% in 2012, and due to leukemia - from 9.2% to 3.6%. Five-year survival rate of patients with leukemia increased from 56.6% to 63.2 % over the period of 2010-2012. Conclusion. The study shows the effectiveness of outpatient hematologic care in St. Petersburg. To further improve the efficiency of outpatient hematologic care in metropolis, it is important to improve the knowledge of hematologic diseases by doctors and pediatricians of general healthcare network, to review the workload of hematological office staff, to focus on preventive component of hematologic care (quality of occupational medical examinations), to develop and implement the new organizational techniques providing costs reduction and improving quality of life.

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HANCHINAL, Vijayashri Basavaraj, Ambhuja SAMBRANI, and Vineet BALJOSHI. "A study on influence of different phases of menstrual cycle on hematological parameters." Journal of Experimental and Clinical Medicine 38, no. 3 (April 23, 2021): 308–11. http://dx.doi.org/10.52142/omujecm.38.3.19.

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Menstruation is the most common phenomenon observed in fertile women. Menstrual cycle (MC) is of 3 phases: proliferative phase, secretory phase and menstruation phase. It is controlled by endocrine system. Natural fluctuations in sex steroid hormones during MC causes changes in hematological parameters. The aim of the present study to assess the impact of different phases of MC on hematological parameters. The study was conducted in KIMS, Hubli, from 01st March 2011 to 31st March 2012. Women aged between 20-30 years with regular menstrual cycle of 27-30 days were included in the study. During each visit, the subjects’ blood was collected and analyzed using KX-21 SYSMEX for various hematological parameters. A total of 50 healthy young women were included in the study. On statistical comparing of hematological parameters, hematocrit, hemoglobin, neutrophil count and eosinophil count showed a significant difference while no statistically significant difference was observed in RBC, leucocyte count, lymphocyte count, monocyte count, erythrocyte sedimentation rate (ESR) and platelet count between different phases of MC. To conclude, the hematological parameters during the MC are highly dependent on the phasic changes in the immune response mechanism and sex steroid hormones.

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Liang, Connie, Ashley Leung, Chung-Shien Lee, Jennifer Hernandez, Kit Cheng, Dimitre C. Stefanov, and Veena S. John. "Retrospective analysis of ovarian cancer patients treated with PARP inhibitors." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e17555-e17555. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e17555.

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e17555 Background: Over the last few years, targeted therapy has become the mainstay maintenance treatment of patients with ovarian cancer including patients with BRCA1 or BRCA2 mutations. Poly ADP ribose polymerase (PARP) inhibitors are effective in the treatment of patients who are in complete or partial remission. PARP inhibitors are known to cause hematological adverse events (AEs), but have not been compared directly to each other. Methods: We conducted a single institution, IRB approved, retrospective study on patients who were treated with PARP inhibitors from December 2016 to October 2020. Patients were stratified according to which PARP inhibitor they received. Our primary objective was to assess the incidence of hematological and non-hematological adverse events associated with the use of PARP inhibitor therapy used in patients with ovarian cancer. Data from absolute neutrophil count, hemoglobin and platelet count during the first 2 cycles were graded for hematologic toxicity according to CTCAE v 5.0. Results: A total of 126 patients received a PARP inhibitor during the study time frame. 34 were excluded and 92 patients were included for analysis. Median age of patients were 64.3 (range, 33.8 to 92.3) years, 66 (71.7%) white, and 84 (91.3%) had an ECOG PS of 0/1. Thirty-one (33.7%) of patients received niraparib and 61 (66.3%) of patients received olaparib. Patients in the niraparib group experienced more hematologic AEs, with 11 (35.5%) (95% CI 19.2-54.6), 20 (64.5%) (95% CI 45.4-80.8), and 18 (58.1%) (95% CI 39.1-75.5) experiencing neutropenia, anemia, thrombocytopenia, respectively. Eight (13.1%) (95% CI 5.8-24.2), 24 (39.3%) (95% CI 27.1-52.7), 16 (26.2%) (95% CI 15.8-39.1) patients in the olaparib group experienced neutropenia, anemia, thrombocytopenia, respectively. Conclusions: This single institution retrospective study outlines the hematological toxicities observed between two PARP inhibitors. Although there are four PARP inhibitors approved by FDA, our data compared only two of the four (as they were the most commonly prescribed PARP inhibitors in our institution). Our results suggested that niraparib tended to be associated with a higher risk for hematologic toxicities than olaparib. Our data showed anemia as the most common hematologic toxicity which was consistent with what has been widely documented in the literature.

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